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Full Results
solute carrier family 12 member 4 isoform c [Homo sapiens]
Protein Classification
solute carrier family 12 protein ( domain architecture ID 11489985 )
solute carrier family 12 protein similar to Arabidopsis thaliana cation-chloride cotransporter 1, which mediates both potassium-chloride and sodium-chloride cotransports and is involved in plant development and Cl(-) homeostasis, or human kidney-specific Na-K-Cl symporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation
List of domain hits
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
70-1087
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1320.87
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 70 TRT E EL D IRP KV S SLLG K L VS YTN LT QG A KEHEEAE SG EGT RRRA - A E A PSM G TL MGV YL PCL Q NI F GVILFLRL T W M VG 148
Cdd:TIGR00930 27 SLE E LH D LLD KV V SLLG P L AD YTN NG QG M KEHEEAE DA EGT KEKP p A G A VKF G WV MGV LV PCL L NI W GVILFLRL S W I VG 106
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 149 T AG VLQA LLI V L I CCC C T LL T AI SMSAIATNGVV PA GG S Y FM ISRSLGPEFGG AV GL C F YLGTTF A A AMY IL G AI E IL L T 228
Cdd:TIGR00930 107 Q AG IGLS LLI I L L CCC V T TI T GL SMSAIATNGVV KG GG A Y YL ISRSLGPEFGG SI GL I F AFANAV A V AMY VV G FA E TV L D 186
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 229 yiappaa IFYPS G a HDTSNATL N NM R V YGT IFLTFMTLVV F V G VKYV NK FAS LFL AC V II SIL S I YA G G I KSI FD P P VFP 308
Cdd:TIGR00930 187 ------- LLREN G - SKIMVDPI N DI R I YGT VTVVVLLGIS F A G MEWE NK AQV LFL VI V LL SIL N I FV G T I IPA FD K P AKG 258
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 309 VCM LGN RTL S RD qfdicaktavvdnetvatqlwsffchspnlttdscdpyfmlnnvt E IPGIPG AAA G vlqenlwsayle 388
Cdd:TIGR00930 259 FFG LGN EIF S EN --------------------------------------------- F IPGIPG PEG G ------------ 281
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 389 kgdivekhglpsadapslkeslplyvvadiats F TV L V GIFFPSVTGI M AG S N R SGDL R D A QK S IP V GT I LAI I TT SL VY 468
Cdd:TIGR00930 282 --------------------------------- F FS L F GIFFPSVTGI L AG A N I SGDL K D P QK A IP K GT L LAI L TT TV VY 328
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 469 FS SVVLFGAC IEGVVLR DK YGDG V S --------------------- R NL V V GT L AW P S P WV I VI G S F FS T CGAG L Q SL TG 527
Cdd:TIGR00930 329 LG SVVLFGAC VVRDATG DK NDTL V T nctsaacfsecahntcsyglm N NL Q V MS L VS P F P PL I TA G I F SA T LSSA L A SL VS 408
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 528 APRL L QA IA KDNI I PFL RV FG H G K - V NGEP TW A L LLTA L IAE LG ILIA S L DMV API L S M FFL MC Y LFV N LA C AVQT LLR T 606
Cdd:TIGR00930 409 APRL F QA LC KDNI Y PFL QF FG K G Y g K NGEP LR A Y LLTA F IAE GF ILIA E L NTI API I S N FFL AS Y ALI N FS C FHAS LLR S 488
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 607 P N WRPRFKYYHW A LS F LG M SLC L A L MF VS SW YY ALVAM L IA GMI YKY IE Y QGAEKE WG DGIRG LS L S A A R Y A LLRLEE GP 686
Cdd:TIGR00930 489 P G WRPRFKYYHW W LS L LG A SLC C A I MF LI SW WA ALVAM V IA LFL YKY VT Y KKPDVN WG SSTQA LS Y S L A L Y S LLRLEE VE 568
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 687 P H T KNWRPQ L LVL LKLD edlh V KY P R LL T FASQ LKA GKGL T I V GSVIQG SF LE SYG EAQAAE QT I KNMM E IE KVK G F CQ V 766
Cdd:TIGR00930 569 D H V KNWRPQ C LVL TGPP ---- V CR P A LL D FASQ FTK GKGL M I C GSVIQG PR LE CVK EAQAAE AK I QTWL E KN KVK A F YA V 644
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 767 VVA SKV REG LA HLIQ SC GLG G M RH N SV V L G WPYG WRQ S E d PRAW K T F I DTVRCTTA AHLA LL V PK N IAFY P SNH ------ 840
Cdd:TIGR00930 645 VVA DDL REG VR HLIQ AS GLG R M KP N TL V M G YKKD WRQ A E - PRAW E T Y I GIIHDAFD AHLA VV V VR N SEGL P ISV lqvqee 723
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 841 -------------------------------- ERYLE G H IDVWW I V H DGG MLM LLP F LL RQH KVW R KC RM RIF TV AQ M DD 888
Cdd:TIGR00930 724 lendcsedsielndgkistqpdmhleastqfq KKQGK G T IDVWW L V D DGG LTL LLP Y LL TTK KVW K KC KI RIF VG AQ K DD 803
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 889 N S I Q M KKD L A VF LY HL R LE AEV E VV E M hns DI S A yt YER T LM ME QRSQ M L R QM RL T KTE RE REA qlv KD RH salrlesly 968
Cdd:TIGR00930 804 R S E Q E KKD M A TL LY KF R ID AEV I VV L M --- DI N A -- KPQ T ES ME AFEE M I R PF RL H KTE KD REA --- KD PK --------- 866
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 969 sdeedesavgadkiq MTWT RDKYM T E twdpshapdnfrelvhi KPD QSNVR RMHTA V K LNE VIVTR S H DA R LV L L NM P G P 1048
Cdd:TIGR00930 867 --------------- MTWT KPWKI T D ----------------- AEL QSNVR KSYRQ V R LNE LLLEY S R DA A LV V L SL P V P 914
1050 1060 1070
....*....|....*....|....*....|....*....
gi 225579063 1049 PRN S EG DE N YM EF LEVL T E G L ER VLLVRG GG R E V I T I YS 1087
Cdd:TIGR00930 915 RKG S IP DE L YM AW LEVL S E D L PP VLLVRG NH R N V L T F YS 953
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
70-1087
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1320.87
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 70 TRT E EL D IRP KV S SLLG K L VS YTN LT QG A KEHEEAE SG EGT RRRA - A E A PSM G TL MGV YL PCL Q NI F GVILFLRL T W M VG 148
Cdd:TIGR00930 27 SLE E LH D LLD KV V SLLG P L AD YTN NG QG M KEHEEAE DA EGT KEKP p A G A VKF G WV MGV LV PCL L NI W GVILFLRL S W I VG 106
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 149 T AG VLQA LLI V L I CCC C T LL T AI SMSAIATNGVV PA GG S Y FM ISRSLGPEFGG AV GL C F YLGTTF A A AMY IL G AI E IL L T 228
Cdd:TIGR00930 107 Q AG IGLS LLI I L L CCC V T TI T GL SMSAIATNGVV KG GG A Y YL ISRSLGPEFGG SI GL I F AFANAV A V AMY VV G FA E TV L D 186
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 229 yiappaa IFYPS G a HDTSNATL N NM R V YGT IFLTFMTLVV F V G VKYV NK FAS LFL AC V II SIL S I YA G G I KSI FD P P VFP 308
Cdd:TIGR00930 187 ------- LLREN G - SKIMVDPI N DI R I YGT VTVVVLLGIS F A G MEWE NK AQV LFL VI V LL SIL N I FV G T I IPA FD K P AKG 258
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 309 VCM LGN RTL S RD qfdicaktavvdnetvatqlwsffchspnlttdscdpyfmlnnvt E IPGIPG AAA G vlqenlwsayle 388
Cdd:TIGR00930 259 FFG LGN EIF S EN --------------------------------------------- F IPGIPG PEG G ------------ 281
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 389 kgdivekhglpsadapslkeslplyvvadiats F TV L V GIFFPSVTGI M AG S N R SGDL R D A QK S IP V GT I LAI I TT SL VY 468
Cdd:TIGR00930 282 --------------------------------- F FS L F GIFFPSVTGI L AG A N I SGDL K D P QK A IP K GT L LAI L TT TV VY 328
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 469 FS SVVLFGAC IEGVVLR DK YGDG V S --------------------- R NL V V GT L AW P S P WV I VI G S F FS T CGAG L Q SL TG 527
Cdd:TIGR00930 329 LG SVVLFGAC VVRDATG DK NDTL V T nctsaacfsecahntcsyglm N NL Q V MS L VS P F P PL I TA G I F SA T LSSA L A SL VS 408
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 528 APRL L QA IA KDNI I PFL RV FG H G K - V NGEP TW A L LLTA L IAE LG ILIA S L DMV API L S M FFL MC Y LFV N LA C AVQT LLR T 606
Cdd:TIGR00930 409 APRL F QA LC KDNI Y PFL QF FG K G Y g K NGEP LR A Y LLTA F IAE GF ILIA E L NTI API I S N FFL AS Y ALI N FS C FHAS LLR S 488
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 607 P N WRPRFKYYHW A LS F LG M SLC L A L MF VS SW YY ALVAM L IA GMI YKY IE Y QGAEKE WG DGIRG LS L S A A R Y A LLRLEE GP 686
Cdd:TIGR00930 489 P G WRPRFKYYHW W LS L LG A SLC C A I MF LI SW WA ALVAM V IA LFL YKY VT Y KKPDVN WG SSTQA LS Y S L A L Y S LLRLEE VE 568
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 687 P H T KNWRPQ L LVL LKLD edlh V KY P R LL T FASQ LKA GKGL T I V GSVIQG SF LE SYG EAQAAE QT I KNMM E IE KVK G F CQ V 766
Cdd:TIGR00930 569 D H V KNWRPQ C LVL TGPP ---- V CR P A LL D FASQ FTK GKGL M I C GSVIQG PR LE CVK EAQAAE AK I QTWL E KN KVK A F YA V 644
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 767 VVA SKV REG LA HLIQ SC GLG G M RH N SV V L G WPYG WRQ S E d PRAW K T F I DTVRCTTA AHLA LL V PK N IAFY P SNH ------ 840
Cdd:TIGR00930 645 VVA DDL REG VR HLIQ AS GLG R M KP N TL V M G YKKD WRQ A E - PRAW E T Y I GIIHDAFD AHLA VV V VR N SEGL P ISV lqvqee 723
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 841 -------------------------------- ERYLE G H IDVWW I V H DGG MLM LLP F LL RQH KVW R KC RM RIF TV AQ M DD 888
Cdd:TIGR00930 724 lendcsedsielndgkistqpdmhleastqfq KKQGK G T IDVWW L V D DGG LTL LLP Y LL TTK KVW K KC KI RIF VG AQ K DD 803
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 889 N S I Q M KKD L A VF LY HL R LE AEV E VV E M hns DI S A yt YER T LM ME QRSQ M L R QM RL T KTE RE REA qlv KD RH salrlesly 968
Cdd:TIGR00930 804 R S E Q E KKD M A TL LY KF R ID AEV I VV L M --- DI N A -- KPQ T ES ME AFEE M I R PF RL H KTE KD REA --- KD PK --------- 866
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 969 sdeedesavgadkiq MTWT RDKYM T E twdpshapdnfrelvhi KPD QSNVR RMHTA V K LNE VIVTR S H DA R LV L L NM P G P 1048
Cdd:TIGR00930 867 --------------- MTWT KPWKI T D ----------------- AEL QSNVR KSYRQ V R LNE LLLEY S R DA A LV V L SL P V P 914
1050 1060 1070
....*....|....*....|....*....|....*....
gi 225579063 1049 PRN S EG DE N YM EF LEVL T E G L ER VLLVRG GG R E V I T I YS 1087
Cdd:TIGR00930 915 RKG S IP DE L YM AW LEVL S E D L PP VLLVRG NH R N V L T F YS 953
AA_permease
pfam00324 Amino acid permease;
125-697
2.48e-50
Amino acid permease;
Pssm-ID: 366028 [Multi-domain]
Cd Length: 467
Bit Score: 185.22
E-value: 2.48e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 125 G V YLPC L QNIF G VI LF LRLTWMV G T AG VLQ ALL IV LI CCCCTL L TAI S MSA I A TNG V V p A GG S Y FMI SR S LGP EF G G A V G 204
Cdd:pfam00324 1 H V QMIA L GGVI G TG LF VGSGSVL G Q AG PAG ALL GY LI SGVVIF L VML S LGE I S TNG P V - S GG F Y TYA SR F LGP SL G F A T G 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 205 L -- CFYLG T TF A AA myi L G A IE IL LTYIAPPAA I F Y psgahdtsnatlnn MR V Y G TI FL TFM T LVVF VGVK YVNKFASL F 282
Cdd:pfam00324 80 W ny WLSWI T VL A LE --- L T A AS IL IQFWELVPD I P Y -------------- LW V W G AV FL VLL T IINL VGVK WYGEAEFW F 142
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 283 LACV II S I LSIYAG GI KSIFDP pvfpvcmlgnrtlsrdqfdicaktavvdnetvatqlwsffchspnlttdscdpyfmln 362
Cdd:pfam00324 143 ALIK II A I IGFIIV GI ILLSGG ---------------------------------------------------------- 164
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 363 nvteipgip GAAA G VLQEN L WSAYLEK gdivekhglpsadapslkeslpl YVVADIATS F TVLVG I F F PSV TGI MAGSNR 442
Cdd:pfam00324 165 --------- NPND G AIFRY L GDNGGKN ----------------------- NFPPGFGKG F ISVFV I A F FAF TGI ELVGIA 212
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 443 S G DLRDAQ KSIP VGTILA I ITTSLV Y FS S VVLF G ACIEGVVLRDKYGDGVSRNLV V ------ G TLAWPS pw V I VIGSFFS 516
Cdd:pfam00324 213 A G EVKNPE KSIP KAILQV I WRITIF Y IL S LLAI G LLVPWNDPGLLNDSASAASPF V iffkfl G ISGLAP -- L I NAVILTA 290
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 517 TCG A GLQ SL TGAP R L L QAI A K D NII P F lr VFGHGKVN G E P TW A L L LTAL I AE L GI L I ASL dm VAP I LSM F F L MCYLFVN L 596
Cdd:pfam00324 291 ALS A ANS SL YSGS R M L YSL A R D GLA P K -- FLKKVDKR G V P LR A I L VSMV I SL L AL L L ASL -- NPA I VFN F L L AISGLSG L 366
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 597 ACAVQTL L RTPNW R PR FKY YHWALSF L GMSLC L ALMF V SSWYY A LVAM LI AGMI Y KYIEYQ G AE K E WG D G IRGLSLSAAR 676
Cdd:pfam00324 367 IVWGLIS L SHLRF R KA FKY QGRSIDE L PFKAP L GPLG V ILGLA A IIII LI IQFL Y AFLPVP G GP K N WG A G SFAAAYLIVL 446
570 580
....*....|....*....|.
gi 225579063 677 YA L LR L EEGPP H T KNW R PQLL 697
Cdd:pfam00324 447 LF L II L IGVKL H V KNW K PQLL 467
PotE
COG0531 Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
133-657
1.54e-32
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain]
Cd Length: 438
Bit Score: 131.94
E-value: 1.54e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 133 N I F G VIL F LRLTWMV G T AG v LQ A L L IV LI CCCCT LL T A I S MSAI A TN gv V P - AGG S Y FMIS R S LGP EF G GAV G LCFY L GT 211
Cdd:COG0531 25 A I I G AGI F VLPGLAA G L AG - PA A I L AW LI AGLLA LL V A L S YAEL A SA -- F P r AGG A Y TYAR R A LGP LL G FLA G WALL L SY 101
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 212 TF A A A MYILGAIEI L ltyiappa AIFY P S G AHD tsnatlnnmr VYGTIFLTFM TL VVFV GVK YVN K FASLFLACVIISI L 291
Cdd:COG0531 102 VL A V A AVAVAFGGY L -------- SSLF P A G GSV ---------- LIALVLILLL TL LNLR GVK ESA K VNNILTVLKLLVL L 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 292 SIYAG G I ksifdppvfpvcmlgnrtlsrdqfdicaktavvdnetvatqlwsffchspnlttdscd PY F MLN N V T EIPGIP 371
Cdd:COG0531 164 LFIVV G L ---------------------------------------------------------- FA F DPA N F T PFLPAG 185
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 372 G AAA GV lqenlwsaylekgdivekhglpsadapslkeslplyvvadiats FTV L VGI FF p SV TG IM A GS N RSGDLRDAQK 451
Cdd:COG0531 186 G GLS GV -------------------------------------------- LAA L ALA FF - AF TG FE A IA N LAEEAKNPKR 220
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 452 S IP VGT IL AIITTSLV Y FSSVVLFG acie GVV LR D KYGDGVSRNLVVGTLAWPSP -- WV I VI G SFF S TC GA GLQ S LT GA P 529
Cdd:COG0531 221 N IP RAI IL SLLIVGVL Y ILVSLALT ---- GVV PY D ELAASGAPLADAAEAVFGPW ga IL I AL G ALL S LL GA LNA S IL GA S 296
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 530 RLL Q A I A K D NII P fl R VF GH - GKVN G E P TW A L LLT AL IA E L GI L I -- AS LDMV A PIL S MFF L MC YL F V N LA CA V Q t LL R T 606
Cdd:COG0531 297 RLL Y A M A R D GLL P -- K VF AK v HPRF G T P VN A I LLT GV IA L L LL L L ga AS FTAL A SLA S VGV L LA YL L V A LA VI V L - RR R R 373
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....
gi 225579063 607 P NWRPR F KYYHWALSF LG MS LCL A L MFVS --- SWYYA LV AML I AGMI Y KYIEYQ 657
Cdd:COG0531 374 P DLPRP F RVPLPLIPI LG IL LCL F L LYLL gpg ALLIG LV LLA I GLLL Y LLYRRR 427
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
70-1087
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1320.87
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 70 TRT E EL D IRP KV S SLLG K L VS YTN LT QG A KEHEEAE SG EGT RRRA - A E A PSM G TL MGV YL PCL Q NI F GVILFLRL T W M VG 148
Cdd:TIGR00930 27 SLE E LH D LLD KV V SLLG P L AD YTN NG QG M KEHEEAE DA EGT KEKP p A G A VKF G WV MGV LV PCL L NI W GVILFLRL S W I VG 106
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 149 T AG VLQA LLI V L I CCC C T LL T AI SMSAIATNGVV PA GG S Y FM ISRSLGPEFGG AV GL C F YLGTTF A A AMY IL G AI E IL L T 228
Cdd:TIGR00930 107 Q AG IGLS LLI I L L CCC V T TI T GL SMSAIATNGVV KG GG A Y YL ISRSLGPEFGG SI GL I F AFANAV A V AMY VV G FA E TV L D 186
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 229 yiappaa IFYPS G a HDTSNATL N NM R V YGT IFLTFMTLVV F V G VKYV NK FAS LFL AC V II SIL S I YA G G I KSI FD P P VFP 308
Cdd:TIGR00930 187 ------- LLREN G - SKIMVDPI N DI R I YGT VTVVVLLGIS F A G MEWE NK AQV LFL VI V LL SIL N I FV G T I IPA FD K P AKG 258
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 309 VCM LGN RTL S RD qfdicaktavvdnetvatqlwsffchspnlttdscdpyfmlnnvt E IPGIPG AAA G vlqenlwsayle 388
Cdd:TIGR00930 259 FFG LGN EIF S EN --------------------------------------------- F IPGIPG PEG G ------------ 281
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 389 kgdivekhglpsadapslkeslplyvvadiats F TV L V GIFFPSVTGI M AG S N R SGDL R D A QK S IP V GT I LAI I TT SL VY 468
Cdd:TIGR00930 282 --------------------------------- F FS L F GIFFPSVTGI L AG A N I SGDL K D P QK A IP K GT L LAI L TT TV VY 328
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 469 FS SVVLFGAC IEGVVLR DK YGDG V S --------------------- R NL V V GT L AW P S P WV I VI G S F FS T CGAG L Q SL TG 527
Cdd:TIGR00930 329 LG SVVLFGAC VVRDATG DK NDTL V T nctsaacfsecahntcsyglm N NL Q V MS L VS P F P PL I TA G I F SA T LSSA L A SL VS 408
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 528 APRL L QA IA KDNI I PFL RV FG H G K - V NGEP TW A L LLTA L IAE LG ILIA S L DMV API L S M FFL MC Y LFV N LA C AVQT LLR T 606
Cdd:TIGR00930 409 APRL F QA LC KDNI Y PFL QF FG K G Y g K NGEP LR A Y LLTA F IAE GF ILIA E L NTI API I S N FFL AS Y ALI N FS C FHAS LLR S 488
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 607 P N WRPRFKYYHW A LS F LG M SLC L A L MF VS SW YY ALVAM L IA GMI YKY IE Y QGAEKE WG DGIRG LS L S A A R Y A LLRLEE GP 686
Cdd:TIGR00930 489 P G WRPRFKYYHW W LS L LG A SLC C A I MF LI SW WA ALVAM V IA LFL YKY VT Y KKPDVN WG SSTQA LS Y S L A L Y S LLRLEE VE 568
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 687 P H T KNWRPQ L LVL LKLD edlh V KY P R LL T FASQ LKA GKGL T I V GSVIQG SF LE SYG EAQAAE QT I KNMM E IE KVK G F CQ V 766
Cdd:TIGR00930 569 D H V KNWRPQ C LVL TGPP ---- V CR P A LL D FASQ FTK GKGL M I C GSVIQG PR LE CVK EAQAAE AK I QTWL E KN KVK A F YA V 644
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 767 VVA SKV REG LA HLIQ SC GLG G M RH N SV V L G WPYG WRQ S E d PRAW K T F I DTVRCTTA AHLA LL V PK N IAFY P SNH ------ 840
Cdd:TIGR00930 645 VVA DDL REG VR HLIQ AS GLG R M KP N TL V M G YKKD WRQ A E - PRAW E T Y I GIIHDAFD AHLA VV V VR N SEGL P ISV lqvqee 723
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 841 -------------------------------- ERYLE G H IDVWW I V H DGG MLM LLP F LL RQH KVW R KC RM RIF TV AQ M DD 888
Cdd:TIGR00930 724 lendcsedsielndgkistqpdmhleastqfq KKQGK G T IDVWW L V D DGG LTL LLP Y LL TTK KVW K KC KI RIF VG AQ K DD 803
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 889 N S I Q M KKD L A VF LY HL R LE AEV E VV E M hns DI S A yt YER T LM ME QRSQ M L R QM RL T KTE RE REA qlv KD RH salrlesly 968
Cdd:TIGR00930 804 R S E Q E KKD M A TL LY KF R ID AEV I VV L M --- DI N A -- KPQ T ES ME AFEE M I R PF RL H KTE KD REA --- KD PK --------- 866
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 969 sdeedesavgadkiq MTWT RDKYM T E twdpshapdnfrelvhi KPD QSNVR RMHTA V K LNE VIVTR S H DA R LV L L NM P G P 1048
Cdd:TIGR00930 867 --------------- MTWT KPWKI T D ----------------- AEL QSNVR KSYRQ V R LNE LLLEY S R DA A LV V L SL P V P 914
1050 1060 1070
....*....|....*....|....*....|....*....
gi 225579063 1049 PRN S EG DE N YM EF LEVL T E G L ER VLLVRG GG R E V I T I YS 1087
Cdd:TIGR00930 915 RKG S IP DE L YM AW LEVL S E D L PP VLLVRG NH R N V L T F YS 953
AA_permease
pfam00324 Amino acid permease;
125-697
2.48e-50
Amino acid permease;
Pssm-ID: 366028 [Multi-domain]
Cd Length: 467
Bit Score: 185.22
E-value: 2.48e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 125 G V YLPC L QNIF G VI LF LRLTWMV G T AG VLQ ALL IV LI CCCCTL L TAI S MSA I A TNG V V p A GG S Y FMI SR S LGP EF G G A V G 204
Cdd:pfam00324 1 H V QMIA L GGVI G TG LF VGSGSVL G Q AG PAG ALL GY LI SGVVIF L VML S LGE I S TNG P V - S GG F Y TYA SR F LGP SL G F A T G 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 205 L -- CFYLG T TF A AA myi L G A IE IL LTYIAPPAA I F Y psgahdtsnatlnn MR V Y G TI FL TFM T LVVF VGVK YVNKFASL F 282
Cdd:pfam00324 80 W ny WLSWI T VL A LE --- L T A AS IL IQFWELVPD I P Y -------------- LW V W G AV FL VLL T IINL VGVK WYGEAEFW F 142
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 283 LACV II S I LSIYAG GI KSIFDP pvfpvcmlgnrtlsrdqfdicaktavvdnetvatqlwsffchspnlttdscdpyfmln 362
Cdd:pfam00324 143 ALIK II A I IGFIIV GI ILLSGG ---------------------------------------------------------- 164
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 363 nvteipgip GAAA G VLQEN L WSAYLEK gdivekhglpsadapslkeslpl YVVADIATS F TVLVG I F F PSV TGI MAGSNR 442
Cdd:pfam00324 165 --------- NPND G AIFRY L GDNGGKN ----------------------- NFPPGFGKG F ISVFV I A F FAF TGI ELVGIA 212
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 443 S G DLRDAQ KSIP VGTILA I ITTSLV Y FS S VVLF G ACIEGVVLRDKYGDGVSRNLV V ------ G TLAWPS pw V I VIGSFFS 516
Cdd:pfam00324 213 A G EVKNPE KSIP KAILQV I WRITIF Y IL S LLAI G LLVPWNDPGLLNDSASAASPF V iffkfl G ISGLAP -- L I NAVILTA 290
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 517 TCG A GLQ SL TGAP R L L QAI A K D NII P F lr VFGHGKVN G E P TW A L L LTAL I AE L GI L I ASL dm VAP I LSM F F L MCYLFVN L 596
Cdd:pfam00324 291 ALS A ANS SL YSGS R M L YSL A R D GLA P K -- FLKKVDKR G V P LR A I L VSMV I SL L AL L L ASL -- NPA I VFN F L L AISGLSG L 366
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 597 ACAVQTL L RTPNW R PR FKY YHWALSF L GMSLC L ALMF V SSWYY A LVAM LI AGMI Y KYIEYQ G AE K E WG D G IRGLSLSAAR 676
Cdd:pfam00324 367 IVWGLIS L SHLRF R KA FKY QGRSIDE L PFKAP L GPLG V ILGLA A IIII LI IQFL Y AFLPVP G GP K N WG A G SFAAAYLIVL 446
570 580
....*....|....*....|.
gi 225579063 677 YA L LR L EEGPP H T KNW R PQLL 697
Cdd:pfam00324 447 LF L II L IGVKL H V KNW K PQLL 467
PotE
COG0531 Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
133-657
1.54e-32
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain]
Cd Length: 438
Bit Score: 131.94
E-value: 1.54e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 133 N I F G VIL F LRLTWMV G T AG v LQ A L L IV LI CCCCT LL T A I S MSAI A TN gv V P - AGG S Y FMIS R S LGP EF G GAV G LCFY L GT 211
Cdd:COG0531 25 A I I G AGI F VLPGLAA G L AG - PA A I L AW LI AGLLA LL V A L S YAEL A SA -- F P r AGG A Y TYAR R A LGP LL G FLA G WALL L SY 101
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 212 TF A A A MYILGAIEI L ltyiappa AIFY P S G AHD tsnatlnnmr VYGTIFLTFM TL VVFV GVK YVN K FASLFLACVIISI L 291
Cdd:COG0531 102 VL A V A AVAVAFGGY L -------- SSLF P A G GSV ---------- LIALVLILLL TL LNLR GVK ESA K VNNILTVLKLLVL L 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 292 SIYAG G I ksifdppvfpvcmlgnrtlsrdqfdicaktavvdnetvatqlwsffchspnlttdscd PY F MLN N V T EIPGIP 371
Cdd:COG0531 164 LFIVV G L ---------------------------------------------------------- FA F DPA N F T PFLPAG 185
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 372 G AAA GV lqenlwsaylekgdivekhglpsadapslkeslplyvvadiats FTV L VGI FF p SV TG IM A GS N RSGDLRDAQK 451
Cdd:COG0531 186 G GLS GV -------------------------------------------- LAA L ALA FF - AF TG FE A IA N LAEEAKNPKR 220
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 452 S IP VGT IL AIITTSLV Y FSSVVLFG acie GVV LR D KYGDGVSRNLVVGTLAWPSP -- WV I VI G SFF S TC GA GLQ S LT GA P 529
Cdd:COG0531 221 N IP RAI IL SLLIVGVL Y ILVSLALT ---- GVV PY D ELAASGAPLADAAEAVFGPW ga IL I AL G ALL S LL GA LNA S IL GA S 296
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 530 RLL Q A I A K D NII P fl R VF GH - GKVN G E P TW A L LLT AL IA E L GI L I -- AS LDMV A PIL S MFF L MC YL F V N LA CA V Q t LL R T 606
Cdd:COG0531 297 RLL Y A M A R D GLL P -- K VF AK v HPRF G T P VN A I LLT GV IA L L LL L L ga AS FTAL A SLA S VGV L LA YL L V A LA VI V L - RR R R 373
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....
gi 225579063 607 P NWRPR F KYYHWALSF LG MS LCL A L MFVS --- SWYYA LV AML I AGMI Y KYIEYQ 657
Cdd:COG0531 374 P DLPRP F RVPLPLIPI LG IL LCL F L LYLL gpg ALLIG LV LLA I GLLL Y LLYRRR 427
SLC12
pfam03522 Solute carrier family 12;
711-1087
1.87e-23
Solute carrier family 12;
Pssm-ID: 460955
Cd Length: 414
Bit Score: 104.24
E-value: 1.87e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 711 P R L LT FA SQLKAGKG L T I V G S V IQ G SF le S YGEAQAAEQTIKNMMEIE K V K G F CQV V VASKV REG LAH L I Q SC GLG GMRH 790
Cdd:pfam03522 2 P A L VD FA HLITKNVS L M I C G H V VK G RL -- S QKLRSELQKKAYRWLRKR K I K A F YAL V DGDNL REG AQA L L Q AS GLG KLKP 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 791 N SVVL G WPYG WR QSE ----------------------------------------------------------------- 805
Cdd:pfam03522 80 N ILLM G YKSD WR TCD keeleeyfnvihdafdlqyavailrlpegldvshllqdqdteelglgdetnssyaeqsseeqsts 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 806 DPRAWKTFIDTVRCTTAAH L ALLV -------------------- P KN I AFYP SN HERY L E ----------- G H IDVWW IV 854
Cdd:pfam03522 160 NSKQDDDKSKLSKKDSNLS L SPDK stknpsgkdssksdklkkks P SI I LRTA SN EKEI L N nitqfqkkqkk G T IDVWW LY 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 855 H DGG MLM LLP FL L RQHKV W RK C RM R I F TVAQMD D NSIQMKKDL A VF L YHL R LE - AEVE V V emhn S DI SAYTYER T L mmeq 933
Cdd:pfam03522 240 D DGG LTL LLP YI L STRSK W SD C KL R V F ALGNRK D ELEEEQRNM A SL L SKF R ID y SDLT V I ---- P DI TKKPKKE T K ---- 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 934 rs QMLRQM rltkterereaqlvkdrhsalr L E SLYSD E E D ESAVG A D KI qmtwtrdkym T ET wdpshapdnfr EL VHI K p 1013
Cdd:pfam03522 312 -- KFFDEL ---------------------- I E PFRLH E D D KEEES A E KI ---------- T DS ----------- EL EAL K - 345
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 225579063 1014 DQS N vr R M hta VK L N E VIVTR S H DA R L VLLNM P G P PRNSEGDEN YM EF LE V LT EG L ERV LLVRG GGRE V I T I YS 1087
Cdd:pfam03522 346 EKT N -- R Q --- LR L R E LLLEH S S DA N L IVMTL P M P RKGTVSAPL YM AW LE T LT KD L PPF LLVRG NQTS V L T F YS 414
AA_permease_2
pfam13520 Amino acid permease;
397-654
4.95e-13
Amino acid permease;
Pssm-ID: 404414 [Multi-domain]
Cd Length: 427
Bit Score: 72.34
E-value: 4.95e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 397 GLPSADAPS L KESLPLYVVA D IATSFTVLVGIFFP S V TG IMAGS N R S GDLR da QKSI P VGTILAI I TTSLV Y FSSVVL F G 476
Cdd:pfam13520 165 VTADGGGFN L LSGEWHTFFP D GWPGVFAGFLGVLW S F TG FESAA N V S EEVK -- KRNV P KAIFIGV I IVGVL Y ILVNIA F F 242
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 477 ACI -- EGVV L RDKY G DGVS --- RNLVVGTL A W pspw VI VI GSFF S TC GA GLQSLT GA P RLL Q A I A K D NII PF L R V F GHGK 551
Cdd:pfam13520 243 GVV pd DEIA L SSGL G QVAA llf QAVGGKWG A I ---- IV VI LLAL S LL GA VNTAIV GA S RLL Y A L A R D GVL PF S R F F AKVN 318
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225579063 552 VN G E P TW A LL LTA LIAELGI L IAS L DMV A PI ---- LS MFFLMCYLFVNLACAV qt L LR TPNWRPRFKYYH W ALSFL G M s L 627
Cdd:pfam13520 319 KF G S P IR A II LTA ILSLILL L LFL L SPA A YN alls LS AYGYLLSYLLPIIGLL -- I LR KKRPDLGRIPGR W PVAIF G I - L 395
250 260
....*....|....*....|....*..
gi 225579063 628 CLALMF V SSWYYALVAMLIAGMI Y KY I 654
Cdd:pfam13520 396 FSLFLI V ALFFPPVGPATGSSLN Y AI I 422
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
