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Conserved domains on  [gi|196259772|ref|NP_001124496|]
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peroxisomal biogenesis factor 5 isoform c [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 332-549 1.46e-18

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 89.67  E-value: 1.46e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 332 MEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAG 411
Cdd:COG3914    1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 412 GAGLGPSKRILGsllsdsLFLEVKELFLAAVRLDPTSidPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKL 491
Cdd:COG3914   81 LELAALLLQALG------RYEEALALYRRALALNPDN--AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNL 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 196259772 492 GATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQ 549
Cdd:COG3914  153 GEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELD 210
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 249-397 4.85e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


:

Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 46.88  E-value: 4.85e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 249 DFWDKLQAELEEMAKRDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLqeGDLPNAVLLFEAAVQQD 328
Cdd:COG5010    7 FDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKL--GDFEESLALLEQALQLD 84

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 196259772 329 PKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTP 397
Cdd:COG5010   85 PNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 332-549 1.46e-18

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 89.67  E-value: 1.46e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 332 MEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAG 411
Cdd:COG3914    1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 412 GAGLGPSKRILGsllsdsLFLEVKELFLAAVRLDPTSidPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKL 491
Cdd:COG3914   81 LELAALLLQALG------RYEEALALYRRALALNPDN--AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNL 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 196259772 492 GATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQ 549
Cdd:COG3914  153 GEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELD 210
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 309-546 4.17e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 69.34  E-value: 4.17e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772  309 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFtneSLQRQACET 388
Cdd:TIGR02917  33 LQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAY---LLQGKFQQV 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772  389 LRdwlrYTPAYAHLVTPAEEGAGGAglgpskRILGSLLSDSLfLEVKELFLAAVRLDPTSidPDVQCGLGVLFNLSGEYD 468
Cdd:TIGR02917 110 LD----ELPGKTLLDDEGAAELLAL------RGLAYLGLGQL-ELAQKSYEQALAIDPRS--LYAKLGLAQLALAENRFD 176

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 196259772  469 KAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHfLEAL 546
Cdd:TIGR02917 177 EARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKH-ADAL 253
TPR_12 pfam13424
Tetratricopeptide repeat;
487-551 3.35e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 45.07  E-value: 3.35e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 196259772  487 LWNKLGATLANGNQSEEAVAAYRRALELQ--------PGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRK 551
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 249-397 4.85e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 46.88  E-value: 4.85e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 249 DFWDKLQAELEEMAKRDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLqeGDLPNAVLLFEAAVQQD 328
Cdd:COG5010    7 FDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKL--GDFEESLALLEQALQLD 84

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 196259772 329 PKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTP 397
Cdd:COG5010   85 PNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 309-540 1.48e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 44.16  E-value: 1.48e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 309 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQ-TALMALA-VSFTNESLQ--RQ 384
Cdd:cd24142   11 LDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGyEKYLYLGqLSGGEEALQyyEK 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 385 ACETLRDWLRytpayahlVTPAEEGAGGAGLGPSKRILGS--------LLSDSLFLE-----VKELFLAAVRLDPTSidP 451
Cdd:cd24142   91 GIEILEEELQ--------ALQAASAEAEEEAEELKRKLSSalcalaeiYMTDLCDEPdaeqrCEELITKALELDPTN--P 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 452 DVQCGLGVLFNLSGEYDKAVDCFTAALSvrpndylLWNKLGATLANGNQSEEAvaayrrALELQPGYiRSRYNLGISCIN 531
Cdd:cd24142  161 EALQTLASLRISQQRPDEAKEALRRSLE-------LWKDLKEEDEEEAEEDEA------EEEDVPSY-EFRISLAKLLIE 226


                 ....*....
gi 196259772 532 LGAHREAVE 540
Cdd:cd24142  227 LEMYEEALE 235
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 451-484 6.65e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.43  E-value: 6.65e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 196259772   451 PDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPND 484
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
PRY smart00589
associated with SPRY domains;
268-303 3.16e-03

associated with SPRY domains;


Pssm-ID: 128857  Cd Length: 52  Bit Score: 36.01  E-value: 3.16e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 196259772   268 AHPWLSDYDDLTSATYDKGYQfeeenPLRDHPQPFE 303
Cdd:smart00589  11 AHPYLLLSEDRRSVRYGDLKQ-----SLPDNPERFD 41
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 332-549 1.46e-18

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 89.67  E-value: 1.46e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 332 MEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAG 411
Cdd:COG3914    1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 412 GAGLGPSKRILGsllsdsLFLEVKELFLAAVRLDPTSidPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKL 491
Cdd:COG3914   81 LELAALLLQALG------RYEEALALYRRALALNPDN--AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNL 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 196259772 492 GATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQ 549
Cdd:COG3914  153 GEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELD 210
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 302-549 6.34e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 84.01  E-value: 6.34e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 302 FEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESL 381
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 382 QRQACETLRDWLRYTPAYAHLVTpaeegaggaglgpskRILGSLLSDSLFLEVKELFLAAVRLDPTsiDPDVQCGLGVLF 461
Cdd:COG2956   92 LDRAEELLEKLLELDPDDAEALR---------------LLAEIYEQEGDWEKAIEVLERLLKLGPE--NAHAYCELAELY 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 462 NLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEH 541
Cdd:COG2956  155 LEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALEL 234


                 ....*...
gi 196259772 542 FLEALNMQ 549
Cdd:COG2956  235 LRKALELD 242
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
436-549 1.35e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 82.75  E-value: 1.35e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 436 ELFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQ 515
Cdd:COG0457   29 EDYEKALELDPD--DAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELD 106

                         90       100       110
                 ....*....|....*....|....*....|....
gi 196259772 516 PGYIRSRYNLGISCINLGAHREAVEHFLEALNMQ 549
Cdd:COG0457  107 PDDAEALYNLGLALLELGRYDEAIEAYERALELD 140
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
325-547 4.18e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 81.21  E-value: 4.18e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 325 VQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACEtlrdwlrytpayahlvt 404
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALA----------------- 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 405 paeegaggaglgpskrilgsllsdslflevkeLFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPND 484
Cdd:COG0457   64 --------------------------------DYEQALELDPD--DAEALNNLGLALQALGRYEEALEDYDKALELDPDD 109

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 196259772 485 YLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALN 547
Cdd:COG0457  110 AEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEA 172
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
442-549 1.10e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 76.97  E-value: 1.10e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 442 VRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRS 521
Cdd:COG0457    1 LELDPD--DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEA 78

                         90       100
                 ....*....|....*....|....*...
gi 196259772 522 RYNLGISCINLGAHREAVEHFLEALNMQ 549
Cdd:COG0457   79 LNNLGLALQALGRYEEALEDYDKALELD 106
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 433-546 2.31e-14

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 70.22  E-value: 2.31e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 433 EVKELFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRAL 512
Cdd:COG4783   22 EAEALLEKALELDPD--NPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKAL 99

                         90       100       110
                 ....*....|....*....|....*....|....
gi 196259772 513 ELQPGYIRSRYNLGISCINLGAHREAVEHFLEAL 546
Cdd:COG4783  100 KLDPEHPEAYLRLARAYRALGRPDEAIAALEKAL 133
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 304-525 3.46e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 75.80  E-value: 3.46e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 304 EGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQEL---------LAISALRRCLELKPDNQTALMALAV 374
Cdd:COG3914    7 LALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAeaaaaallaLAAGEAAAAAAALLLLAALLELAAL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 375 SFTNESLQRQACETLRDWLRYTPAYAhlvtpaeegaggaglgPSKRILGSLLSDS-LFLEVKELFLAAVRLDPTsiDPDV 453
Cdd:COG3914   87 LLQALGRYEEALALYRRALALNPDNA----------------EALFNLGNLLLALgRLEEALAALRRALALNPD--FAEA 148

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 196259772 454 QCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNL 525
Cdd:COG3914  149 YLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 440-548 7.95e-14

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 68.49  E-value: 7.95e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 440 AAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYI 519
Cdd:COG4235    8 QALAANPN--DAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85

                         90       100
                 ....*....|....*....|....*....
gi 196259772 520 RSRYNLGISCINLGAHREAVEHFLEALNM 548
Cdd:COG4235   86 EALYLLGLAAFQQGDYAEAIAAWQKLLAL 114
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
457-546 1.56e-13

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 70.33  E-value: 1.56e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 457 LGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHR 536
Cdd:COG4785   79 RGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYE 158

                         90
                 ....*....|
gi 196259772 537 EAVEHFLEAL 546
Cdd:COG4785  159 LAIADLEKAL 168
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 309-546 4.17e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 69.34  E-value: 4.17e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772  309 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFtneSLQRQACET 388
Cdd:TIGR02917  33 LQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAY---LLQGKFQQV 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772  389 LRdwlrYTPAYAHLVTPAEEGAGGAglgpskRILGSLLSDSLfLEVKELFLAAVRLDPTSidPDVQCGLGVLFNLSGEYD 468
Cdd:TIGR02917 110 LD----ELPGKTLLDDEGAAELLAL------RGLAYLGLGQL-ELAQKSYEQALAIDPRS--LYAKLGLAQLALAENRFD 176

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 196259772  469 KAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHfLEAL 546
Cdd:TIGR02917 177 EARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKH-ADAL 253
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 309-549 5.09e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 66.68  E-value: 5.09e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 309 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGttQAENEQELL--AISALRRCLELKPDNQTALMALAVSFTNESLQRQAC 386
Cdd:COG2956   53 RRRGEYDRAIRIHQKLLERDPDRAEALLELA--QDYLKAGLLdrAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAI 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 387 ETLRDWLRYTPAYAHLVTpaeegaggaglgpskrILGSLLSD-SLFLEVKELFLAAVRLDPTSIDpdVQCGLGVLFNLSG 465
Cdd:COG2956  131 EVLERLLKLGPENAHAYC----------------ELAELYLEqGDYDEAIEALEKALKLDPDCAR--ALLLLAELYLEQG 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 466 EYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGyIRSRYNLGISCINLGAHREAVEHFLEA 545
Cdd:COG2956  193 DYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS-DDLLLALADLLERKEGLEAALALLERQ 271


                 ....
gi 196259772 546 LNMQ 549
Cdd:COG2956  272 LRRH 275
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 457-549 5.12e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 60.59  E-value: 5.12e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 457 LGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHR 536
Cdd:COG4783   10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD 89

                         90
                 ....*....|...
gi 196259772 537 EAVEHFLEALNMQ 549
Cdd:COG4783   90 EALALLEKALKLD 102
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
465-553 7.25e-11

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 59.03  E-value: 7.25e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 465 GEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVaAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLE 544
Cdd:COG3063    6 GDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLER 84


                 ....*....
gi 196259772 545 ALNMQRKSR 553
Cdd:COG3063   85 ALELDPSAL 93
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 296-525 1.84e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 63.95  E-value: 1.84e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772  296 RDHPQP-FEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAV 374
Cdd:TIGR02917 258 PNSPLAhYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLAS 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772  375 SFTNESLQRQACETLRDWLRYTPAYAHLVTpaeegaggaglgpskrILGS-LLSDSLFLEVKELFLAAVRLDPTSIDPDV 453
Cdd:TIGR02917 338 IQLRLGRVDEAIATLSPALGLDPDDPAALS----------------LLGEaYLALGDFEKAAEYLAKATELDPENAAART 401

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772  454 QcgLGVLFNLSGEYDKAVDCFTAALSV----------------------------------RPNDYLLWNKLGATLANGN 499
Cdd:TIGR02917 402 Q--LGISKLSQGDPSEAIADLETAAQLdpelgradlllilsylrsgqfdkalaaakklekkQPDNASLHNLLGAIYLGKG 479

                         250       260
                  ....*....|....*....|....*.
gi 196259772  500 QSEEAVAAYRRALELQPGYIRSRYNL 525
Cdd:TIGR02917 480 DLAKAREAFEKALSIEPDFFPAAANL 505
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 459-547 4.01e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 58.82  E-value: 4.01e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 459 VLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREA 538
Cdd:COG5010   62 NLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEA 141


                 ....*....
gi 196259772 539 VEHFLEALN 547
Cdd:COG5010  142 KAALQRALG 150
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 436-552 3.84e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.82  E-value: 3.84e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 436 ELFLAAVRLDPTSIDpdVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQ 515
Cdd:COG2956   29 DLLEEALELDPETVE--AHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELD 106

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 196259772 516 PGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKS 552
Cdd:COG2956  107 PDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPEN 143
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 469-546 4.08e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 52.32  E-value: 4.08e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 196259772 469 KAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEAL 546
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERAL 78
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 317-484 8.50e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.16  E-value: 8.50e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 317 AVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQAcetlrdwlryt 396
Cdd:COG4235    2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEA----------- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 397 payahlvtpaeegaggaglgpskrilgsllsdslflevKELFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTA 476
Cdd:COG4235   71 --------------------------------------EELLERALALDPD--NPEALYLLGLAAFQQGDYAEAIAAWQK 110


                 ....*...
gi 196259772 477 ALSVRPND 484
Cdd:COG4235  111 LLALLPAD 118
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 457-552 9.78e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 53.58  E-value: 9.78e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 457 LGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHR 536
Cdd:COG2956   14 KGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLD 93

                         90
                 ....*....|....*.
gi 196259772 537 EAVEHFLEALNMQRKS 552
Cdd:COG2956   94 RAEELLEKLLELDPDD 109
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 436-552 1.15e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 53.58  E-value: 1.15e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 436 ELFLAAVRLDPTSidPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQ 515
Cdd:COG2956   63 RIHQKLLERDPDR--AEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLG 140

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 196259772 516 PGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKS 552
Cdd:COG2956  141 PENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDC 177
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
438-558 1.64e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 52.22  E-value: 1.64e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 438 FLAAVRLDPTSidPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPG 517
Cdd:COG4785   96 FDQALELDPDL--AEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPN 173

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 196259772 518 YIRSRYNLGISCINLGAHrEAVEHFLEALNMQRKSRGPRGE 558
Cdd:COG4785  174 DPERALWLYLAERKLDPE-KALALLLEDWATAYLLQGDTEE 213
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 431-516 2.79e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 50.34  E-value: 2.79e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 431 FLEVKELFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRR 510
Cdd:COG5010   70 FEESLALLEQALQLDPN--NPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQR 147


                 ....*.
gi 196259772 511 ALELQP 516
Cdd:COG5010  148 ALGTSP 153
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 436-518 2.81e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 50.19  E-value: 2.81e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 436 ELFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQ 515
Cdd:COG4783   59 VLLHEALELDPD--EPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136


                 ...
gi 196259772 516 PGY 518
Cdd:COG4783  137 PDD 139
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 296-516 7.46e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.39  E-value: 7.46e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772  296 RDHPQPFE-EGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAV 374
Cdd:TIGR02917 598 PDSPEAWLmLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQ 677

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772  375 SFTNESLQRQACETLRDWLRYTPAYAhlvtpaeegaggaglgpskriLGSLLSDSLFLEVKEL------FLAAVRLDPTS 448
Cdd:TIGR02917 678 LLLAAKRTESAKKIAKSLQKQHPKAA---------------------LGFELEGDLYLRQKDYpaaiqaYRKALKRAPSS 736

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 196259772  449 idpDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQP 516
Cdd:TIGR02917 737 ---QNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAP 801
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 309-551 1.11e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 51.62  E-value: 1.11e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772  309 LQEGDLPNAVLLFEAAVQQDPKHMEAWQ-----------------YLGTTQAENEQEL-----------------LAISA 354
Cdd:TIGR02917 510 IQEGNPDDAIQRFEKVLTIDPKNLRAILalaglylrtgneeeavaWLEKAAELNPQEIepalalaqyylgkgqlkKALAI 589

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772  355 LRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTP--AYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFL 432
Cdd:TIGR02917 590 LNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPdsALALLLLADAYAVMKNYAKAITSLKRALELKPDNT 669

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772  433 EVK----ELFLAAVRLDPT-----------SIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLAN 497
Cdd:TIGR02917 670 EAQiglaQLLLAAKRTESAkkiakslqkqhPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIKLHRALLAS 749

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 196259772  498 GNQSeEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRK 551
Cdd:TIGR02917 750 GNTA-EAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPD 802
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 296-400 1.60e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.88  E-value: 1.60e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 296 RDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVS 375
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                         90       100
                 ....*....|....*....|....*
gi 196259772 376 FTNESLQRQACETLRDWLRYTPAYA 400
Cdd:COG4783   82 LLKAGDYDEALALLEKALKLDPEHP 106
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
435-516 2.07e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 46.32  E-value: 2.07e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 435 KELFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDcFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALEL 514
Cdd:COG3063   12 EEYYEKALELDPD--NADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALEL 88


                 ..
gi 196259772 515 QP 516
Cdd:COG3063   89 DP 90
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 436-516 2.69e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.92  E-value: 2.69e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 436 ELFLAAVRLDPTsiDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQ 515
Cdd:COG4235   38 AAYEKALRLDPD--NADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALL 115


                 .
gi 196259772 516 P 516
Cdd:COG4235  116 P 116
TPR_12 pfam13424
Tetratricopeptide repeat;
487-551 3.35e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 45.07  E-value: 3.35e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 196259772  487 LWNKLGATLANGNQSEEAVAAYRRALELQ--------PGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRK 551
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 309-400 3.36e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.54  E-value: 3.36e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 309 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACET 388
Cdd:COG4235   28 LRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAA 107

                         90
                 ....*....|..
gi 196259772 389 LRDWLRYTPAYA 400
Cdd:COG4235  108 WQKLLALLPADA 119
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
302-376 3.44e-06

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 48.37  E-value: 3.44e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 196259772 302 FEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSF 376
Cdd:COG4785   77 YERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIAL 151
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 288-397 4.34e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.57  E-value: 4.34e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 288 QFEEENPLRDHPQpFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQT 367
Cdd:COG2956  135 RLLKLGPENAHAY-CELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLP 213

                         90       100       110
                 ....*....|....*....|....*....|
gi 196259772 368 ALMALAVSFTNESLQRQACETLRDWLRYTP 397
Cdd:COG2956  214 ALPRLAELYEKLGDPEEALELLRKALELDP 243
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 249-397 4.85e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 46.88  E-value: 4.85e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 249 DFWDKLQAELEEMAKRDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLqeGDLPNAVLLFEAAVQQD 328
Cdd:COG5010    7 FDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKL--GDFEESLALLEQALQLD 84

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 196259772 329 PKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTP 397
Cdd:COG5010   85 PNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 309-399 6.09e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 46.34  E-value: 6.09e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 309 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACET 388
Cdd:COG4783   49 LQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAA 128

                         90
                 ....*....|.
gi 196259772 389 LRDWLRYTPAY 399
Cdd:COG4783  129 LEKALELDPDD 139
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
309-398 1.18e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 44.01  E-value: 1.18e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 309 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAIsALRRCLELKPDNQTALMALAVSFTNESLQRQACET 388
Cdd:COG3063    3 LKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEALAY 81

                         90
                 ....*....|
gi 196259772 389 LRDWLRYTPA 398
Cdd:COG3063   82 LERALELDPS 91
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 308-370 1.85e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 44.61  E-value: 1.85e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 196259772 308 RLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALM 370
Cdd:COG4235   61 LLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARL 123
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 464-547 2.56e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 43.83  E-value: 2.56e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 464 SGEYDKAVDCFTAALSVRPNDYLLWN---KLGATLANGNQSEEAVAAYRRALELQPGYIR---SRYNLGISCINLGAHRE 537
Cdd:COG1729    6 AGDYDEAIAAFKAFLKRYPNSPLAPDalyWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELGDYDK 85

                         90
                 ....*....|
gi 196259772 538 AVEHFLEALN 547
Cdd:COG1729   86 ARATLEELIK 95
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
305-445 3.22e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 45.77  E-value: 3.22e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 305 GLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQ 384
Cdd:COG0457   83 GLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEE 162

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 196259772 385 ACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLD 445
Cdd:COG0457  163 ALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELL 223
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 476-582 3.55e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.18  E-value: 3.55e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 476 AALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKsrgp 555
Cdd:COG5010   45 AGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPD---- 120

                         90       100
                 ....*....|....*....|....*..
gi 196259772 556 rgeggamSENIWSTLRLALSMLGQSDA 582
Cdd:COG5010  121 -------NPNAYSNLAALLLSLGQDDE 140
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 309-547 3.80e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.00  E-value: 3.80e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772  309 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTA-LMALAVSFTNEslQRQACE 387
Cdd:TIGR02917 680 LAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAiKLHRALLASGN--TAEAVK 757

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772  388 TLRDWLRYTPAYAHLVTpaeegaggaglgpskrilgsLLSDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEY 467
Cdd:TIGR02917 758 TLEAWLKTHPNDAVLRT--------------------ALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLEL 817

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772  468 D--KAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEA 545
Cdd:TIGR02917 818 KdpRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAEARKELDKL 897


                  ..
gi 196259772  546 LN 547
Cdd:TIGR02917 898 LN 899
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
481-546 4.09e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 45.29  E-value: 4.09e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 196259772 481 RPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEAL 546
Cdd:COG4785   69 LPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRAL 134
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
305-400 4.97e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 45.00  E-value: 4.97e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 305 GLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQ 384
Cdd:COG0457   49 GLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDE 128

                         90
                 ....*....|....*.
gi 196259772 385 ACETLRDWLRYTPAYA 400
Cdd:COG0457  129 AIEAYERALELDPDDA 144
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 309-540 1.48e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 44.16  E-value: 1.48e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 309 LQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQ-TALMALA-VSFTNESLQ--RQ 384
Cdd:cd24142   11 LDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGyEKYLYLGqLSGGEEALQyyEK 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 385 ACETLRDWLRytpayahlVTPAEEGAGGAGLGPSKRILGS--------LLSDSLFLE-----VKELFLAAVRLDPTSidP 451
Cdd:cd24142   91 GIEILEEELQ--------ALQAASAEAEEEAEELKRKLSSalcalaeiYMTDLCDEPdaeqrCEELITKALELDPTN--P 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 452 DVQCGLGVLFNLSGEYDKAVDCFTAALSvrpndylLWNKLGATLANGNQSEEAvaayrrALELQPGYiRSRYNLGISCIN 531
Cdd:cd24142  161 EALQTLASLRISQQRPDEAKEALRRSLE-------LWKDLKEEDEEEAEEDEA------EEEDVPSY-EFRISLAKLLIE 226


                 ....*....
gi 196259772 532 LGAHREAVE 540
Cdd:cd24142  227 LEMYEEALE 235
TPR_1 pfam00515
Tetratricopeptide repeat;
451-484 3.57e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.17  E-value: 3.57e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 196259772  451 PDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPND 484
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 451-484 6.65e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.43  E-value: 6.65e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 196259772   451 PDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPND 484
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
LcrH_SycD TIGR02552
type III secretion low calcium response chaperone LcrH/SycD; Genes in this family are found in ...
 464-572 7.53e-04

type III secretion low calcium response chaperone LcrH/SycD; Genes in this family are found in type III secretion operons. LcrH, from Yersinia is believed to have a regulatory function in the low-calcium response of the secretion system. The same protein is also known as SycD (SYC = Specific Yop Chaperone) for its chaperone role. In Pseudomonas, where the homolog is known as PcrH, the chaperone role has been demonstrated and the regulatory role appears to be absent. ScyD/LcrH contains three central tetratricopeptide-like repeats that are predicted to fold into an all-alpha-helical array.


Pssm-ID: 274197 [Multi-domain]  Cd Length: 135  Bit Score: 39.97  E-value: 7.53e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772  464 SGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFL 543
Cdd:TIGR02552  30 QGRYDEALKLFQLLAAYDPYNSRYWLGLAACCQMLKEYEEAIDAYALAAALDPDDPRPYFHAAECLLALGEPESALKALD 109

                          90       100
                  ....*....|....*....|....*....
gi 196259772  544 EALNMQRKSRgprgEGGAMSENIWSTLRL 572
Cdd:TIGR02552 110 LAIEICGENP----EYSELKERAEAMLES 134
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 450-517 1.40e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 41.05  E-value: 1.40e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 450 DPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPN--DYLLwnkLGATLANGNQSEEAVAAYRRALELQPG 517
Cdd:COG3071  257 DPDLLLALGRLCLRNQLWGKAREYLEAALALRPSaeAYAE---LARLLEQLGDPEEAAEHYRKALALALG 323
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 309-390 1.87e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 38.43  E-value: 1.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 309 LQEGDLPNAVLLFEAAVQQDPKHM---EAWQYLGTTQAENEQELLAISALRRCLELKPDNQT---ALMALAVSFTNESLQ 382
Cdd:COG1729    4 LKAGDYDEAIAAFKAFLKRYPNSPlapDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELGDY 83


                 ....*...
gi 196259772 383 RQACETLR 390
Cdd:COG1729   84 DKARATLE 91
TPR_12 pfam13424
Tetratricopeptide repeat;
453-514 2.56e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 36.98  E-value: 2.56e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772  453 VQCGLGVLFNLSGEYDKAVDCFTAALSV--------RPNDYLLWNKLGATLANGNQSEEAVAAYRRALEL 514
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIarrllgpdHPLTATTLLNLGRLYLELGRYEEALELLERALAL 74
PRY smart00589
associated with SPRY domains;
268-303 3.16e-03

associated with SPRY domains;


Pssm-ID: 128857  Cd Length: 52  Bit Score: 36.01  E-value: 3.16e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 196259772   268 AHPWLSDYDDLTSATYDKGYQfeeenPLRDHPQPFE 303
Cdd:smart00589  11 AHPYLLLSEDRRSVRYGDLKQ-----SLPDNPERFD 41
TPR_11 pfam13414
TPR repeat;
499-526 3.46e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 35.53  E-value: 3.46e-03
                          10        20
                  ....*....|....*....|....*...
gi 196259772  499 NQSEEAVAAYRRALELQPGYIRSRYNLG 526
Cdd:pfam13414   8 GKYEEAIEAYKKALKLDPDNPEAYYNLG 35
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 488-553 3.90e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.86  E-value: 3.90e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 196259772 488 WNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSR 553
Cdd:COG4783    7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEP 72
TPR_1 pfam00515
Tetratricopeptide repeat;
488-518 4.61e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.09  E-value: 4.61e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 196259772  488 WNKLGATLANGNQSEEAVAAYRRALELQPGY 518
Cdd:pfam00515   4 LYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 433-517 6.34e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 36.89  E-value: 6.34e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 196259772 433 EVKELFLAAVRLDPTS-IDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPN-----DYLLwnKLGATLANGNQSEEAVA 506
Cdd:COG1729   11 EAIAAFKAFLKRYPNSpLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkapDALL--KLGLSYLELGDYDKARA 88

                         90
                 ....*....|.
gi 196259772 507 AYRRALELQPG 517
Cdd:COG1729   89 TLEELIKKYPD 99
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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