|
Name |
Accession |
Description |
Interval |
E-value |
| TMF_TATA_bd |
pfam12325 |
TATA element modulatory factor 1 TATA binding; This is the C-terminal conserved coiled coil ... |
974-1085 |
7.92e-32 |
|
TATA element modulatory factor 1 TATA binding; This is the C-terminal conserved coiled coil region of a family of TATA element modulatory factor 1 proteins conserved in eukaryotes. The proteins bind to the TATA element of some RNA polymerase II promoters and repress their activity. by competing with the binding of TATA binding protein. TMF1_TATA_bd is the most conserved part of the TMFs. TMFs are evolutionarily conserved golgins that bind Rab6, a ubiquitous ras-like GTP-binding Golgi protein, and contribute to Golgi organization in animal and plant cells. The Rab6-binding domain appears to be the same region as this C-terminal family.
Pssm-ID: 432481 [Multi-domain] Cd Length: 115 Bit Score: 120.34 E-value: 7.92e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 974 AVRMGAGSSIIENLQSQLKLREGEISHLQLEISNLEKTRSIMSEELVKLTNQNDELEEKVKEIPKLRVQLRDLDQRYNTI 1053
Cdd:pfam12325 4 TSGAGPSVQLVERLSSTIRRLEGELASLKEELARLEAQRDEARQEIVKLMKENEELKELKKELEELEKELKELEQRYETT 83
|
90 100 110
....*....|....*....|....*....|..
gi 124487429 1054 LQMYGEKAEEAEELRLDLEDVKNMYKTQIDEL 1085
Cdd:pfam12325 84 LELLGEKSEEVEELKADVEDLKEMYREQVQQL 115
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
450-1085 |
8.43e-18 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 89.35 E-value: 8.43e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 450 EFLNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEMKTI 529
Cdd:TIGR02168 242 EELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEEL 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 530 KEELATRLNSSQ-TADLLKEKDEQIQGLMEEgeklskqqlhnsniIKKLRAKDKDNENVIAKLNRKAKELEEELQHLRQV 608
Cdd:TIGR02168 322 EAQLEELESKLDeLAEELAELEEKLEELKEE--------------LESLEAELEELEAELEELESRLEELEEQLETLRSK 387
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 609 LDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKANAAKDSEVQEAALRREM 688
Cdd:TIGR02168 388 VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELR 467
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 689 KAKEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKEDylRHEISELQQRLQEAENRNQELSQSVS----- 763
Cdd:TIGR02168 468 EELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKN--QSGLSGILGVLSELISVDEGYEAAIEaalgg 545
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 764 ------------------------------------------STARPLLRQIENLQATLGSQTSSWETLEKSLSDRLG-- 799
Cdd:TIGR02168 546 rlqavvvenlnaakkaiaflkqnelgrvtflpldsikgteiqGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGgv 625
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 800 -------ESQTLLAAAVERERAATEE-LLANK---IQMSSVESQNTLL--RQENSRLQAQLESEKNKLRKLEDENSRYQV 866
Cdd:TIGR02168 626 lvvddldNALELAKKLRPGYRIVTLDgDLVRPggvITGGSAKTNSSILerRREIEELEEKIEELEEKIAELEKALAELRK 705
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 867 ELENLKDEYV---RTLEESRKEKTLLSSQLEMERMKVEQERKKTIFTQEALKEKDHKLFSVCSTPTMSRSSSISGVD--- 940
Cdd:TIGR02168 706 ELEELEEELEqlrKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAeie 785
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 941 -----AAGLQASFLSQDESHDHSFGPMS-TSASGSNLYEAV-----RMGAGSSIIENLQSQLKLREGEISHLQLEISNLE 1009
Cdd:TIGR02168 786 eleaqIEQLKEELKALREALDELRAELTlLNEEAANLRERLeslerRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 1010 KTRSIMSEELVKLTNQNDELEEKVKEI----PKLRVQLRDLDQRYNTILQMYGEKAEEAEELRLDLEDVKNMYKTQIDEL 1085
Cdd:TIGR02168 866 ELIEELESELEALLNERASLEEALALLrselEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
452-918 |
3.67e-16 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 83.83 E-value: 3.67e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 452 LNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEMKTIKE 531
Cdd:COG1196 244 LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEE 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 532 ELATRLN---------SSQTADLLKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLNRKA------K 596
Cdd:COG1196 324 ELAELEEeleeleeelEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAelaaqlE 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 597 ELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKANAAKD 676
Cdd:COG1196 404 ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELL 483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 677 SEVQEAALRREMK--AKEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAA-------------RKEDYLRHEI 741
Cdd:COG1196 484 EELAEAAARLLLLleAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALeaalaaalqnivvEDDEVAAAAI 563
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 742 SELQQRLQEAENRNQELSQSVSSTARPLLRQIENLQATLGSQTSS------WETLEKSLSDRLGESQTLLAAAVERERAA 815
Cdd:COG1196 564 EYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLreadarYYVLGDTLLGRTLVAARLEAALRRAVTLA 643
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 816 TEELLANKIQMSSVESQNTLLRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEYVRTLEESRKEKTLLSSQLEM 895
Cdd:COG1196 644 GRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEE 723
|
490 500
....*....|....*....|...
gi 124487429 896 ERMKVEQERKKTIFTQEALKEKD 918
Cdd:COG1196 724 EALEEQLEAEREELLEELLEEEE 746
|
|
| TMF_DNA_bd |
pfam12329 |
TATA element modulatory factor 1 DNA binding; This is the middle region of a family of TATA ... |
540-613 |
1.13e-15 |
|
TATA element modulatory factor 1 DNA binding; This is the middle region of a family of TATA element modulatory factor 1 proteins conserved in eukaryotes that contains at its N-terminal section a number of leucine zippers that could potentially form coiled coil structures.. The whole proteins bind to the TATA element of some RNA polymerase II promoters and repress their activity. by competing with the binding of TATA binding protein. TMFs are evolutionarily conserved golgins that bind Rab6, a ubiquitous ras-like GTP-binding Golgi protein, and contribute to Golgi organization in animal and plant cells.
Pssm-ID: 372049 [Multi-domain] Cd Length: 74 Bit Score: 72.72 E-value: 1.13e-15
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 124487429 540 SQTADLLKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLNRKAKELEEELQHLRQVLDGKE 613
Cdd:pfam12329 1 SSLEKLLKEKDEQIAQLMEEGEKLSKKELKLNNTIKKLRAKNKELEKEIAELKKKLEKLEKELENLEERLKRAE 74
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
460-1089 |
1.27e-15 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 82.29 E-value: 1.27e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 460 ETQLLSLSKEKALLEEaYDNLKDEMFRVKEESSSISslKDEFTQRIAEAEKKVQLACKERDAAKKEMKTIKEELAT-RLN 538
Cdd:COG1196 199 ERQLEPLERQAEKAER-YRELKEELKELEAELLLLK--LRELEAELEELEAELEELEAELEELEAELAELEAELEElRLE 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 539 SSQTADLLKEKDEQIQGLMEEGEKLSKQQLHNsniikKLRAKDkdnenviakLNRKAKELEEELQHLRQVLDGKEEVEKQ 618
Cdd:COG1196 276 LEELELELEEAQAEEYELLAELARLEQDIARL-----EERRRE---------LEERLEELEEELAELEEELEELEEELEE 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 619 HRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELtdLHKANAAKDSEVQEAALRREMKAKEELSGAL 698
Cdd:COG1196 342 LEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL--LEALRAAAELAAQLEELEEAEEALLERLERL 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 699 EKAQEEARQQQEALVLQVGDLRLALQRAEQAAAR---KEDYLRHEISELQQRLQEAENRNQELSQSVSSTARPLLRQIEN 775
Cdd:COG1196 420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAEleeEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 776 LQATLGSQTSSWETLEKSLSDRLGESQTLLAAAVERERAATEELLAnkiqmssVESQNTLLRQENSRLQAQLESEKNKLR 855
Cdd:COG1196 500 EADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALA-------AALQNIVVEDDEVAAAAIEYLKAAKAG 572
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 856 KLEdensryqvELENLKDEYVRTLEESRKEKTLLSSQLEMERMKVEQERKKTIFTQEALKEkdhklfsvcstptmsrsss 935
Cdd:COG1196 573 RAT--------FLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR------------------- 625
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 936 isgVDAAGLQASFLSQDESHDHSFGPMSTSASGSNLYEAVRMGAGSSIIENLQSQLKLREGEISHLQLEISNLEKTRSIM 1015
Cdd:COG1196 626 ---TLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAE 702
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 124487429 1016 SEELVKLTNQNDELEEKVKEIPKLRVQLRDLDQRYNTILQMYGEKAEEAEELRLDLEDVKNMYKTQIDELLRQR 1089
Cdd:COG1196 703 EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
519-1090 |
3.75e-15 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 80.75 E-value: 3.75e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 519 RDAAKKEMKTIKEELaTRLNssqtaDLLKEKDEQI-------------QGLMEEGEKLSKQQLHNSniIKKLRAKDKDNE 585
Cdd:COG1196 174 KEEAERKLEATEENL-ERLE-----DILGELERQLeplerqaekaeryRELKEELKELEAELLLLK--LRELEAELEELE 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 586 NVIAKLNRKAKELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYREL 665
Cdd:COG1196 246 AELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEEL 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 666 TDLHKANAAKDSEVQEAALRREMKAKE-ELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKEDYLRHEISEL 744
Cdd:COG1196 326 AELEEELEELEEELEELEEELEEAEEElEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEEL 405
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 745 QQRLQEAENRNQELSQSVSSTARPLLRQIENLQATLGSQTSSWETLEKSLSDRLgESQTLLAAAVERERAATEELLANKI 824
Cdd:COG1196 406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE-ALLELLAELLEEAALLEAALAELLE 484
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 825 QMSSVESQNTLLRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEYVRTLEEsrkekTLLSSQLEMERMKVEQER 904
Cdd:COG1196 485 ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE-----AALAAALQNIVVEDDEVA 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 905 KKTIftqEALKEKDHKLFSVCSTPTMSRSSSISGVDAAGLQASFLSQDESHDHSFGPMSTSASGSNL---YEAVRMGAGS 981
Cdd:COG1196 560 AAAI---EYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLgrtLVAARLEAAL 636
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 982 SIIENLQSQLKLREGEISHLQLEISNLE-KTRSIMSEELVKLTNQNDELEEKVKEIPKLRVQLRDLDQRyntilqmyGEK 1060
Cdd:COG1196 637 RRAVTLAGRLREVTLEGEGGSAGGSLTGgSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEE--------ERE 708
|
570 580 590
....*....|....*....|....*....|
gi 124487429 1061 AEEAEELRLDLEDVKNMYKTQIDELLRQRL 1090
Cdd:COG1196 709 LAEAEEERLEEELEEEALEEQLEAEREELL 738
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
447-906 |
3.58e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 77.28 E-value: 3.58e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 447 KTVEFLNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEM 526
Cdd:COG1196 302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 527 KTIKEELATRLNS-SQTADLLKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLNRKAKELEEELQHL 605
Cdd:COG1196 382 EELAEELLEALRAaAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 606 RQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSA-----YRELTDLHKANAAKDSEVQ 680
Cdd:COG1196 462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAglrglAGAVAVLIGVEAAYEAALE 541
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 681 EAALRREMKAKEELSGALEKAQEEARQQQEALV--LQVGDLRLALQRAEQAAARKEDYLRHEISELQQRLQEAENRNQEL 758
Cdd:COG1196 542 AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAtfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 759 SQSVSSTARPLL---RQIENLQATLGSQTSSWETLEKSLSDRLGESQTLLAAAVERERAATEELLANKIQMSSVESQNTL 835
Cdd:COG1196 622 LLGRTLVAARLEaalRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 124487429 836 LRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEYVRTLEESRKEkTLLSSQLEMERMKVEQERKK 906
Cdd:COG1196 702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE-ALEELPEPPDLEELERELER 771
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
453-903 |
6.29e-14 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 76.21 E-value: 6.29e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 453 NEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEMKTIKEE 532
Cdd:TIGR04523 116 KEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNK 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 533 LAT---------------RLNSSQTADL----------LKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDNENV 587
Cdd:TIGR04523 196 LLKlelllsnlkkkiqknKSLESQISELkkqnnqlkdnIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKE 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 588 IAKLNRKAKELEEELQHLRQVLdgkEEVEKQHRENI-KKLNSVVERQEKDLGRLQVDMDELEEKsrstqaaLDSAYRELT 666
Cdd:TIGR04523 276 LEQNNKKIKELEKQLNQLKSEI---SDLNNQKEQDWnKELKSELKNQEKKLEEIQNQISQNNKI-------ISQLNEQIS 345
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 667 DLHKANAAKDSEVQEaaLRREMKAKEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKEDylrhEISELQQ 746
Cdd:TIGR04523 346 QLKKELTNSESENSE--KQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDE----QIKKLQQ 419
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 747 RLQEAENRNQELSQSVS---STARPLLRQIENLQATLGSQTSSWETLEKSLSDRLGESQTLlaaaVERERAATEELLANK 823
Cdd:TIGR04523 420 EKELLEKEIERLKETIIknnSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKI----KQNLEQKQKELKSKE 495
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 824 IQMSSVESQNTLLRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEYVR---TLEESRKEKTLLSSQLEMERMKV 900
Cdd:TIGR04523 496 KELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKddfELKKENLEKEIDEKNKEIEELKQ 575
|
...
gi 124487429 901 EQE 903
Cdd:TIGR04523 576 TQK 578
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
452-750 |
1.32e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 75.48 E-value: 1.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 452 LNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEMKTI-- 529
Cdd:TIGR02168 682 LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELea 761
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 530 -KEELATRLNSSQTAdlLKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLNRKAKELEEELQHLRQV 608
Cdd:TIGR02168 762 eIEELEERLEEAEEE--LAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERR 839
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 609 LDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKANAAKDSEVQEA--ALRR 686
Cdd:TIGR02168 840 LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELrrELEE 919
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 124487429 687 EMKAKEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKEDYLRHEISELQQRLQE 750
Cdd:TIGR02168 920 LREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
588-884 |
1.61e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 72.01 E-value: 1.61e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 588 IAKLNRKAKELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTD 667
Cdd:TIGR02168 679 IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE 758
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 668 LHKANAAKDSEVQEAalRREMKAKEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARkedyLRHEISELQQR 747
Cdd:TIGR02168 759 LEAEIEELEERLEEA--EEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAAN----LRERLESLERR 832
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 748 LQEAENRNQELSQsvssTARPLLRQIENLQATLGSQTSSWETLE---KSLSDRLGESQTLLAAAVERERAATEELLANKI 824
Cdd:TIGR02168 833 IAATERRLEDLEE----QIEELSEDIESLAAEIEELEELIEELEselEALLNERASLEEALALLRSELEELSEELRELES 908
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 124487429 825 QMSSVESQNTLLRQENSRLQAQLESEKNKLRKLEDE-NSRYQVELENLKDEYVRTLEESRK 884
Cdd:TIGR02168 909 KRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlSEEYSLTLEEAEALENKIEDDEEE 969
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
524-1085 |
1.84e-12 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 71.59 E-value: 1.84e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 524 KEMKTIKEELATRLNSSQTAD-LLKEKDEQIQGLMEEGEKLSKQqlhnsniIKKLRAKDKDNENVIAKLNRKAKELEEEL 602
Cdd:TIGR04523 40 KKLKTIKNELKNKEKELKNLDkNLNKDEEKINNSNNKIKILEQQ-------IKDLNDKLKKNKDKINKLNSDLSKINSEI 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 603 QHLRQVLDGKE----EVEKQHREN---IKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDlhKANAAK 675
Cdd:TIGR04523 113 KNDKEQKNKLEvelnKLEKQKKENkknIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLN--IQKNID 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 676 DSEVQEAALRREM---KAKEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKEDYLRHEISELQQRLQEAE 752
Cdd:TIGR04523 191 KIKNKLLKLELLLsnlKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLS 270
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 753 NRNQELSQSVS--STARPLLRQIENLQATLGSQTSswETLEKSLSDRLGESQTLLAAAVERERAATEELLANKIQMSSVE 830
Cdd:TIGR04523 271 EKQKELEQNNKkiKELEKQLNQLKSEISDLNNQKE--QDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLK 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 831 SQNTLLRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEyVRTLEESRKEKTLLSSQLEMERMKVEQERKKtift 910
Cdd:TIGR04523 349 KELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQ-INDLESKIQNQEKLNQQKDEQIKKLQQEKEL---- 423
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 911 qealKEKDHKLFSVCSTptmsrsssisgvdaagLQASFLSQDESHDHSFgpmstsasgSNLYEAVRmgagsSIIENLQSQ 990
Cdd:TIGR04523 424 ----LEKEIERLKETII----------------KNNSEIKDLTNQDSVK---------ELIIKNLD-----NTRESLETQ 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 991 LKLREGEISHLQLEISNLEKTRSIMSEELVKLTNQNDELEEKVK----EIPKLRVQLRDLDQRYNTILQMYGEKAEEAEE 1066
Cdd:TIGR04523 470 LKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKdltkKISSLKEKIEKLESEKKEKESKISDLEDELNK 549
|
570
....*....|....*....
gi 124487429 1067 LRLDLEdvKNMYKTQIDEL 1085
Cdd:TIGR04523 550 DDFELK--KENLEKEIDEK 566
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
425-920 |
1.91e-11 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 68.63 E-value: 1.91e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 425 ATEQCEAVENQPKAppekEDVCKTVEFLNEKLEKRetqllslsKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQR 504
Cdd:PTZ00121 1311 AEEAKKADEAKKKA----EEAKKKADAAKKKAEEA--------KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKK 1378
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 505 IAEAEKKVQLACKERDAAKK---EMKTIKEELATRLNSSQTADLLKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKD 581
Cdd:PTZ00121 1379 KADAAKKKAEEKKKADEAKKkaeEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKK 1458
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 582 KDNENVIAKLNRKAKELEEELQHLRQVLDGK---EEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDEL---EEKSRSTQ 655
Cdd:PTZ00121 1459 AEEAKKKAEEAKKADEAKKKAEEAKKADEAKkkaEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAkkaEEAKKADE 1538
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 656 AALDSAYRELTDLHKANAAKDSEVQEAAlRREMKAKEELSGALEKAqEEARQQQEALVLQVGDLRLALQRAEQAAARKED 735
Cdd:PTZ00121 1539 AKKAEEKKKADELKKAEELKKAEEKKKA-EEAKKAEEDKNMALRKA-EEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAE 1616
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 736 YLRHEISELQQRLQEAENRNQELSQSVSSTARP-LLRQIENLQATLGSQTSSWETLEKSLSDRLGESQTLLAAAVERERA 814
Cdd:PTZ00121 1617 EAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAeELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKK 1696
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 815 ATEEllankiqmssvesqntllRQENSRLQAQLESEKNK---LRKLEDENSRYQVELENLKDEYVRTLEESRKEktllss 891
Cdd:PTZ00121 1697 EAEE------------------AKKAEELKKKEAEEKKKaeeLKKAEEENKIKAEEAKKEAEEDKKKAEEAKKD------ 1752
|
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 124487429 892 qlEMERMKVEQERK------------KTIFTQEALKEKDHK 920
Cdd:PTZ00121 1753 --EEEKKKIAHLKKeeekkaeeirkeKEAVIEEELDEEDEK 1791
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
198-920 |
1.98e-11 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 68.63 E-value: 1.98e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 198 VNVNTTEDVSTTSTQSLTAETKDMALEPKEQKHEDR-------QSNTPSPPVSSFSSGTSTTSDIEVLDHESVISESSAS 270
Cdd:PTZ00121 1024 FNIEKIEELTEYGNNDDVLKEKDIIDEDIDGNHEGKaeakahvGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEA 1103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 271 SRQETSDAKSSLHLMQTSFQLLSASACPEYSRLDDFQKLNESCCSSDAfeRIDSFSVQSLDSRSVSEINSDDELPGKGYA 350
Cdd:PTZ00121 1104 KKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDA--KRVEIARKAEDARKAEEARKAEDAKKAEAA 1181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 351 LVPIIVSPSTPKTKVVESTEENAEEEEGNETLVAPSEEAELEESGRSATPVNCDQPDILASPTAGSGGHSASGPATEQCE 430
Cdd:PTZ00121 1182 RKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEAR 1261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 431 AVENQPKAPPEKEDVCKTVEFLNEKLEKRETQLLSLSKEKALLEEAYDNL--KDEMFRVKEESSSISSLKDEFTQRIAEA 508
Cdd:PTZ00121 1262 MAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAeeAKKADEAKKKAEEAKKKADAAKKKAEEA 1341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 509 EKKVQLACKERDAAKKEMKTIKEEL-ATRLNSSQT---ADLLKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDN 584
Cdd:PTZ00121 1342 KKAAEAAKAEAEAAADEAEAAEEKAeAAEKKKEEAkkkADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKAD 1421
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 585 E-NVIAKLNRKAKELEEELQHLRQVLDGKEEVEKQHR-ENIKKLNSVVERQE--KDLGRLQVDMDELEEKSRSTQAALDS 660
Cdd:PTZ00121 1422 EaKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKaEEAKKKAEEAKKADeaKKKAEEAKKADEAKKKAEEAKKKADE 1501
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 661 AYRELTDLHKANAAKDSEvqEAALRREMKAKEELSGALE-KAQEEARQQQEalVLQVGDLRLALQRAEQAAARKEDYLRH 739
Cdd:PTZ00121 1502 AKKAAEAKKKADEAKKAE--EAKKADEAKKAEEAKKADEaKKAEEKKKADE--LKKAEELKKAEEKKKAEEAKKAEEDKN 1577
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 740 EISELQQRLQEAENRNQELSQSVSSTARPL----LRQIEnlQATLGSQTSSWETLEKSLSDRLGESQTLLAAAVERERAA 815
Cdd:PTZ00121 1578 MALRKAEEAKKAEEARIEEVMKLYEEEKKMkaeeAKKAE--EAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKA 1655
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 816 TEELLANKIQMSSVESQNTlLRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEYVRTLEESRKEKTLLSSQLEM 895
Cdd:PTZ00121 1656 EEENKIKAAEEAKKAEEDK-KKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEE 1734
|
730 740
....*....|....*....|....*
gi 124487429 896 ERMKVEQERKKtifTQEALKEKDHK 920
Cdd:PTZ00121 1735 AKKEAEEDKKK---AEEAKKDEEEK 1756
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
447-886 |
1.68e-10 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 65.17 E-value: 1.68e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 447 KTVEFLNEKLEKRETQLlslsKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQL--ACKERDAAKK 524
Cdd:COG4717 64 RKPELNLKELKELEEEL----KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLlpLYQELEALEA 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 525 EMKTIKEELatrlnssqtaDLLKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDK-DNENVIAKLNRKAKELEEELQ 603
Cdd:COG4717 140 ELAELPERL----------EELEERLEELRELEEELEELEAELAELQEELEELLEQLSlATEEELQDLAEELEELQQRLA 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 604 HLRQVLDGKEEVEKQHRENIKKLNSVVERQEKD---------------LGRLQVDMDELEEKSRS------TQAALDSAY 662
Cdd:COG4717 210 ELEEELEEAQEELEELEEELEQLENELEAAALEerlkearlllliaaaLLALLGLGGSLLSLILTiagvlfLVLGLLALL 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 663 RELTDLHKANAAKDSEVQEAALRREMKAKEELSGALEK---AQEEARQQQEALVLQVGDLRLALQRAEQAAAR-KEDYLR 738
Cdd:COG4717 290 FLLLAREKASLGKEAEELQALPALEELEEEELEELLAAlglPPDLSPEELLELLDRIEELQELLREAEELEEElQLEELE 369
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 739 HEISELQQRLQeAENRNQ-ELSQSVSSTARPLLRQIENLQATLGSQTSSWETL-----EKSLSDRLGESQTLLAAAVERE 812
Cdd:COG4717 370 QEIAALLAEAG-VEDEEElRAALEQAEEYQELKEELEELEEQLEELLGELEELlealdEEELEEELEELEEELEELEEEL 448
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 124487429 813 RAATEELLANKIQMSSVESQNTLlrqenSRLQAQLESEKNKLRKLEDENSRYQVELENLKdeyvRTLEESRKEK 886
Cdd:COG4717 449 EELREELAELEAELEQLEEDGEL-----AELLQELEELKAELRELAEEWAALKLALELLE----EAREEYREER 513
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
591-922 |
3.45e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 64.32 E-value: 3.45e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 591 LNRKAKELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQvdmdELEEKSRSTQAALDSAYRELTDLhk 670
Cdd:TIGR02169 690 LSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLE----ELEEDLSSLEQEIENVKSELKEL-- 763
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 671 anaAKDSEVQEAALRREMKAKEELSGALEKAQ-EEARQQQEALVLQVGDLRLALQRAEQAAAR---KEDYLRHEISELQQ 746
Cdd:TIGR02169 764 ---EARIEELEEDLHKLEEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEARLREIEQKLNRltlEKEYLEKEIQELQE 840
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 747 RLQEAENRNQELSQsvsstarpllrQIENLQATLGSQTSSWETLEKSLSDRLGEsqtlLAAAVERERAATEELLANKIQM 826
Cdd:TIGR02169 841 QRIDLKEQIKSIEK-----------EIENLNGKKEELEEELEELEAALRDLESR----LGDLKKERDELEAQLRELERKI 905
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 827 SSVESQNTLLRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEyvRTLEESRKEKTLLSSQLEMERMKVEQERKK 906
Cdd:TIGR02169 906 EELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSL--EDVQAELQRVEEEIRALEPVNMLAIQEYEE 983
|
330
....*....|....*.
gi 124487429 907 TIFTQEALKEKDHKLF 922
Cdd:TIGR02169 984 VLKRLDELKEKRAKLE 999
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
671-907 |
4.95e-10 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 62.86 E-value: 4.95e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 671 ANAAKDSEVQEAALRREMKAKEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKEDylrhEISELQQRLQE 750
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEA----ELAELEKEIAE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 751 AENRNQELSQSVSSTARPLLRQIENLQATLGSQTSSWETLEKSLsdrlgesqTLLAAAVERERAATEELLANKIQMSSVE 830
Cdd:COG4942 95 LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRL--------QYLKYLAPARREQAEELRADLAELAALR 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 124487429 831 SQNTLLRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEYVRTLEESRKEKTLLSSQLEMERMKVEQERKKT 907
Cdd:COG4942 167 AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
612-921 |
9.48e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.15 E-value: 9.48e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 612 KEEVEKQ---HRENIKKLNSVVERQEKDLGRL--QVDMDE--LEEKSRSTQAALDSAYRELTDLHKA-----NAAKDSEV 679
Cdd:TIGR02168 174 RKETERKlerTRENLDRLEDILNELERQLKSLerQAEKAEryKELKAELRELELALLVLRLEELREEleelqEELKEAEE 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 680 QEAALRREMKAKEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQaaarkedylrhEISELQQRLQEAENRNQELS 759
Cdd:TIGR02168 254 ELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQ-----------QKQILRERLANLERQLEELE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 760 QSVSSTARPLLRQIENLqATLGSQTSSWETLEKSLSDRLGESQTLLAAAVERERAATEELLANKIQMSSVESQNTLLRQE 839
Cdd:TIGR02168 323 AQLEELESKLDELAEEL-AELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNE 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 840 NSRLQAQLESEKNKLRKLEDENSRYQVELENL-KDEYVRTLEESRKEKTLLSSQLEMERMKVEQERKKTIFTQEALKEKD 918
Cdd:TIGR02168 402 IERLEARLERLEDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAE 481
|
...
gi 124487429 919 HKL 921
Cdd:TIGR02168 482 REL 484
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
447-923 |
1.26e-09 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 62.39 E-value: 1.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 447 KTVEFLNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLAcKERDAAKKEM 526
Cdd:PRK03918 231 KELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLS-EFYEEYLDEL 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 527 KTIKEELAtrlNSSQTADLLKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLNR----KAKELEEEL 602
Cdd:PRK03918 310 REIEKRLS---RLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEElerlKKRLTGLTP 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 603 QHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAaldsAYRELTDLHKANAAKDSEVQEA 682
Cdd:PRK03918 387 EKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPV----CGRELTEEHRKELLEEYTAELK 462
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 683 ALRREMKakeELSGALEKAQEEARQQQEALVLQVGDLRLaLQRAEQAAARKEDYLRHEISELQQRLQEAENRNQELSQsV 762
Cdd:PRK03918 463 RIEKELK---EIEEKERKLRKELRELEKVLKKESELIKL-KELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIK-L 537
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 763 SSTARPLLRQIENLQATlgsqTSSWETLEKSLSDRLGESQTLLAAAVERERAATEELlankiqmssvesqntllrqeNSR 842
Cdd:PRK03918 538 KGEIKSLKKELEKLEEL----KKKLAELEKKLDELEEELAELLKELEELGFESVEEL--------------------EER 593
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 843 LQaQLESEKNKLRKLEDENSRYQVELENLKDEYvRTLEESRKEKTLLSSQLEMERMKVEQERKKtiFTQEALKEKDHKLF 922
Cdd:PRK03918 594 LK-ELEPFYNEYLELKDAEKELEREEKELKKLE-EELDKAFEELAETEKRLEELRKELEELEKK--YSEEEYEELREEYL 669
|
.
gi 124487429 923 S 923
Cdd:PRK03918 670 E 670
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
468-796 |
1.28e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 62.77 E-value: 1.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 468 KEKAL--LEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEMKTIKEELATRLNS-SQTAD 544
Cdd:TIGR02168 174 RKETErkLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEElKEAEE 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 545 LLKEKDEQIQglmEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLNRkakeLEEELQHLRQVLDGKEEVEKQHRENIK 624
Cdd:TIGR02168 254 ELEELTAELQ---ELEEKLEELRLEVSELEEEIEELQKELYALANEISR----LEQQKQILRERLANLERQLEELEAQLE 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 625 KLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKANAAKDSEVQE-----AALRREMKAKEELSGALE 699
Cdd:TIGR02168 327 ELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETlrskvAQLELQIASLNNEIERLE 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 700 KAQEEARQQQEALVLQVGDLRLALQRAE-QAAARKEDYLRHEISELQQRLQEAENRNQELSQSVsSTARPLLRQIENLQA 778
Cdd:TIGR02168 407 ARLERLEDRRERLQQEIEELLKKLEEAElKELQAELEELEEELEELQEELERLEEALEELREEL-EEAEQALDAAERELA 485
|
330
....*....|....*...
gi 124487429 779 TLGSQTSSWETLEKSLSD 796
Cdd:TIGR02168 486 QLQARLDSLERLQENLEG 503
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
530-872 |
2.13e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 62.01 E-value: 2.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 530 KEELAT-RLNSSQTADLLKEKDEQIQGLMEEGEKLSKQQlhnsniikKLRAKDKDNEnVIAKLNRKaKELEEELQHLRQV 608
Cdd:TIGR02169 176 LEELEEvEENIERLDLIIDEKRQQLERLRREREKAERYQ--------ALLKEKREYE-GYELLKEK-EALERQKEAIERQ 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 609 LDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDEL-EEKSRSTQAALDSAYRELTDLHKANAAKDSEVQEAAlRRE 687
Cdd:TIGR02169 246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAE-ERL 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 688 MKAKEELSGALEKAQEEARQQQEalvlqvgdlrLALQRAEQAAARKEdyLRHEISELQQRLQEAENRNQELSQSVSSTAR 767
Cdd:TIGR02169 325 AKLEAEIDKLLAEIEELEREIEE----------ERKRRDKLTEEYAE--LKEELEDLRAELEEVDKEFAETRDELKDYRE 392
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 768 PLLRQIENLQATLGSQTSSWETLEKsLSDRLGESQTLLAAAVERERAATEELLANKIQMSSVESQNTLLRQENSRLQAQL 847
Cdd:TIGR02169 393 KLEKLKREINELKRELDRLQEELQR-LSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL 471
|
330 340
....*....|....*....|....*
gi 124487429 848 ESEKNKLRKLEDENSRYQVELENLK 872
Cdd:TIGR02169 472 YDLKEEYDRVEKELSKLQRELAEAE 496
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
441-873 |
3.00e-09 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 61.19 E-value: 3.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 441 EKEDVCKTVEFLNEKLEKRETQLLSLSKekalLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERD 520
Cdd:TIGR04523 181 EKLNIQKNIDKIKNKLLKLELLLSNLKK----KIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLN 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 521 AAKKEMKTIKEELATRLNSSQTAD-LLKEKDEQIQGLMEEGEKLS--KQQLHNSNIIKKLRAKDKD----------NENV 587
Cdd:TIGR04523 257 QLKDEQNKIKKQLSEKQKELEQNNkKIKELEKQLNQLKSEISDLNnqKEQDWNKELKSELKNQEKKleeiqnqisqNNKI 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 588 IAKLNRKAKELEEELQHL--------RQVLDGKEEVEKQHREN------IKKLNSVVERQEKDLGRLQVDMDELEEKSRS 653
Cdd:TIGR04523 337 ISQLNEQISQLKKELTNSesensekqRELEEKQNEIEKLKKENqsykqeIKNLESQINDLESKIQNQEKLNQQKDEQIKK 416
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 654 TQAALDSAYRELTDLHKANAAKDSEVQEaaLRREMKAKEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARK 733
Cdd:TIGR04523 417 LQQEKELLEKEIERLKETIIKNNSEIKD--LTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK 494
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 734 EDylrhEISELQQRLQEAENRNQELSQSVSSTARPLlRQIENLQATLGSQTSS-------------WETLEK-------- 792
Cdd:TIGR04523 495 EK----ELKKLNEEKKELEEKVKDLTKKISSLKEKI-EKLESEKKEKESKISDledelnkddfelkKENLEKeideknke 569
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 793 ---------SLSDRLGESQTLLAAAVERERAATEELLANKIQMSSVESQNTLLRQENSRLQAQLESEKNKLRKLEDENSR 863
Cdd:TIGR04523 570 ieelkqtqkSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQ 649
|
490
....*....|
gi 124487429 864 YQVELENLKD 873
Cdd:TIGR04523 650 IKETIKEIRN 659
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
441-798 |
3.06e-09 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 61.21 E-value: 3.06e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 441 EKEDVCKTVEFLNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERD 520
Cdd:PRK02224 364 EAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVE 443
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 521 AAKKEMKTIK-EELATRLNSSQTADLLKEKDEQIQGLMEEGEKLSKQQlhnsniikklrakdkdnENVIAKLNR--KAKE 597
Cdd:PRK02224 444 EAEALLEAGKcPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEV-----------------EEVEERLERaeDLVE 506
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 598 LEEELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKANAAKDS 677
Cdd:PRK02224 507 AEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKE 586
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 678 EVQE-AALRREMKAKEELSGALEKAQEEARQQQEalvlqvgdlrLALQRAEQAAARKE--DYLRHE-----ISELQQRLQ 749
Cdd:PRK02224 587 RIESlERIRTLLAAIADAEDEIERLREKREALAE----------LNDERRERLAEKRErkRELEAEfdearIEEAREDKE 656
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 124487429 750 EAEnrnqELSQSVSSTARPLLRQIENLQATLGSQTSSWETLEkSLSDRL 798
Cdd:PRK02224 657 RAE----EYLEQVEEKLDELREERDDLQAEIGAVENELEELE-ELRERR 700
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
437-767 |
4.39e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 60.85 E-value: 4.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 437 KAPPEKEDVCKTVEFLNEKLEKRETQLLSLSKEKALLEEaYDNLKDEM--FRVKEESSSISSL---KDEFTQRIAEAEKK 511
Cdd:TIGR02169 174 KALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER-YQALLKEKreYEGYELLKEKEALerqKEAIERQLASLEEE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 512 VQLACKERDAAKKEMKTIK---EELATRLN--SSQTADLLKEKDEQIQG-----------LMEEGEKLSKQQLHNSNIIK 575
Cdd:TIGR02169 253 LEKLTEEISELEKRLEEIEqllEELNKKIKdlGEEEQLRVKEKIGELEAeiaslersiaeKERELEDAEERLAKLEAEID 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 576 KLRAKDKDNENVIAKLNRKAKELEEELQHLRQVLDGK----EEVEKQHRENIKKLNSVVERQEKdlgrLQVDMDELEEKS 651
Cdd:TIGR02169 333 KLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLraelEEVDKEFAETRDELKDYREKLEK----LKREINELKREL 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 652 RSTQAALDSAYRELTDLHKANAAKDSEVQEAALRREMKAKEelsgalekaQEEARQQQEALVLQVGDLRLALQRAEQAAA 731
Cdd:TIGR02169 409 DRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALE---------IKKQEWKLEQLAADLSKYEQELYDLKEEYD 479
|
330 340 350
....*....|....*....|....*....|....*.
gi 124487429 732 RKEDylrhEISELQQRLQEAENRNQELSQSVSSTAR 767
Cdd:TIGR02169 480 RVEK----ELSKLQRELAEAEAQARASEERVRGGRA 511
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
452-676 |
5.38e-09 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 59.39 E-value: 5.38e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 452 LNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEMKTIKE 531
Cdd:COG4942 25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 532 ELATRL-----NSSQTADLLKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKdkdnenvIAKLNRKAKELEEELQHLR 606
Cdd:COG4942 105 ELAELLralyrLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRAD-------LAELAALRAELEAERAELE 177
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 607 QVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKANAAKD 676
Cdd:COG4942 178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
454-1089 |
9.40e-09 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 59.85 E-value: 9.40e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 454 EKLEKRETQLLSLSKEKALLEEAYdnlKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQlacKERDAAKKEMKTIKEEL 533
Cdd:pfam12128 244 TKLQQEFNTLESAELRLSHLHFGY---KSDETLIASRQEERQETSAELNQLLRTLDDQWK---EKRDELNGELSAADAAV 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 534 AtrlNSSQTADLLKEKDEQIQGLMEEGEKLSKQQLHNsniikkLRAKDKDNENVIAKLNRKAKELEEELQHLRQVLDgke 613
Cdd:pfam12128 318 A---KDRSELEALEDQHGAFLDADIETAAADQEQLPS------WQSELENLEERLKALTGKHQDVTAKYNRRRSKIK--- 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 614 evekqhreniKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKANAAKDSEVQEAALRRE------ 687
Cdd:pfam12128 386 ----------EQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELklrlnq 455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 688 MKAKEELSGALEKAQEEARQQQEALVlQVGDLRLALQRAEQAAARKEDYLRHEISELQQRLQEAENRNQELSQSVSSTAR 767
Cdd:pfam12128 456 ATATPELLLQLENFDERIERAREEQE-AANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAG 534
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 768 PLLrqienlqATLGSQTSSWETLEKSLSDRLGESQTLLAAAVERERAATE------ELLANKIQMSSVESQNTLLRQENS 841
Cdd:pfam12128 535 TLL-------HFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGElnlygvKLDLKRIDVPEWAASEEELRERLD 607
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 842 RLQAQLESEKNKLRKLEDENSRYQVELENLKdeyvrtLEESRKEKTLLSSQLEMERMKVEQERKKtIFTQEALKEkdHKL 921
Cdd:pfam12128 608 KAEEALQSAREKQAAAEEQLVQANGELEKAS------REETFARTALKNARLDLRRLFDEKQSEK-DKKNKALAE--RKD 678
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 922 FSVCSTPTMSRSSSISGVDAAGLQASFlsQDESHDHSfgpMSTSASGSNLYEA--VRMGAGSSIIENLQSQLKlreGEIS 999
Cdd:pfam12128 679 SANERLNSLEAQLKQLDKKHQAWLEEQ--KEQKREAR---TEKQAYWQVVEGAldAQLALLKAAIAARRSGAK---AELK 750
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 1000 HLQLEISNLEKTRSIMSEELVKLTNQNDELEEKVKEIPKLRVQLRDLDQRYN-TILQMYGEKAEEAEELRLDLEDVKNMY 1078
Cdd:pfam12128 751 ALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQeTWLQRRPRLATQLSNIERAISELQQQL 830
|
650
....*....|.
gi 124487429 1079 KTQIDELLRQR 1089
Cdd:pfam12128 831 ARLIADTKLRR 841
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
441-708 |
2.15e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 58.53 E-value: 2.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 441 EKEDVCKTVEFLNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERD 520
Cdd:TIGR02168 755 ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIA 834
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 521 AAKKEMKTIKEELAtrlnssQTADLLKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLNRKAKELEE 600
Cdd:TIGR02168 835 ATERRLEDLEEQIE------ELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELES 908
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 601 ELQHLRQVLDGKEEVEKQHRENIKKLNSVVER-QEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKA-------N 672
Cdd:TIGR02168 909 KRSELRRELEELREKLAQLELRLEGLEVRIDNlQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKikelgpvN 988
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 124487429 673 AAKDSEVQEAALRRE---------MKAKEELSGALEKAQEEARQQ 708
Cdd:TIGR02168 989 LAAIEEYEELKERYDfltaqkedlTEAKETLEEAIEEIDREARER 1033
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
537-771 |
3.10e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 57.08 E-value: 3.10e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 537 LNSSQTADLLKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLNRKAKELEEELQHLRQVLDGKEEVE 616
Cdd:COG4942 13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 617 KQHRENIKKLNSVVERQEKDLGRL-QVDMDELEEKSRSTQAALDSA--YRELTDLHKANAAKDSEVQE--AALRREMKAK 691
Cdd:COG4942 93 AELRAELEAQKEELAELLRALYRLgRQPPLALLLSPEDFLDAVRRLqyLKYLAPARREQAEELRADLAelAALRAELEAE 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 692 EELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKEDYLRHEISELQQRLQEAENRNQELSQSVSSTARPLLR 771
Cdd:COG4942 173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALK 252
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
427-1077 |
3.78e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 57.77 E-value: 3.78e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 427 EQCEAVENQ-PKAPPEKEDVCKTVEFLNEKLEKRETQLLSLSKE-KALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQR 504
Cdd:TIGR02169 237 RQKEAIERQlASLEEELEKLTEEISELEKRLEEIEQLLEELNKKiKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERE 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 505 IAEAEKKVQLACKERDAAKKEMKTIKEELAT-RLNSSQTADLLKEKDEQIQGLMEEGEKLSKQqlhnsniIKKLRAKDKD 583
Cdd:TIGR02169 317 LEDAEERLAKLEAEIDKLLAEIEELEREIEEeRKRRDKLTEEYAELKEELEDLRAELEEVDKE-------FAETRDELKD 389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 584 NENVIAKLNRKAKELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYR 663
Cdd:TIGR02169 390 YREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQ 469
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 664 ELTDLHKANAAKDSEVQEaaLRREMKAKEELSGALEKAQEEARQQQEAL----------VLQVGDLRLALQRAEQAAA-- 731
Cdd:TIGR02169 470 ELYDLKEEYDRVEKELSK--LQRELAEAEAQARASEERVRGGRAVEEVLkasiqgvhgtVAQLGSVGERYATAIEVAAgn 547
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 732 -------RKEDYLRHEISELQQR-------LQEAENRNQELSQSVSSTA----------------RPLLRQI-------E 774
Cdd:TIGR02169 548 rlnnvvvEDDAVAKEAIELLKRRkagratfLPLNKMRDERRDLSILSEDgvigfavdlvefdpkyEPAFKYVfgdtlvvE 627
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 775 NLQA------------------------TLGSQTSSWETL--------EKSLSDRLGESQTLLAAAVERERAATEELLAN 822
Cdd:TIGR02169 628 DIEAarrlmgkyrmvtlegelfeksgamTGGSRAPRGGILfsrsepaeLQRLRERLEGLKRELSSLQSELRRIENRLDEL 707
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 823 KIQMSSVESQNTLLRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEyVRTLEESRKEKTLLSSQLEMERMKVEQ 902
Cdd:TIGR02169 708 SQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSE-LKELEARIEELEEDLHKLEEALNDLEA 786
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 903 ERKKTIFTQ-EALKEKDHKLFSVCSTPTMSRSSSISGVDAAGLQASFLSQDESHDHSFGPMSTSASGSNLYEA-VRMGAG 980
Cdd:TIGR02169 787 RLSHSRIPEiQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLnGKKEEL 866
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 981 SSIIENLQSQLKLREGEISHLQLEISNLEKTRSIMSEELVKLTNQNDELEEKVKEipkLRVQLRDLDQRYNTILQMYGEK 1060
Cdd:TIGR02169 867 EEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSE---LKAKLEALEEELSEIEDPKGED 943
|
730
....*....|....*..
gi 124487429 1061 AEEAEELrLDLEDVKNM 1077
Cdd:TIGR02169 944 EEIPEEE-LSLEDVQAE 959
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
574-939 |
4.33e-08 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 57.67 E-value: 4.33e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 574 IKKLRAKDKDNENVIAKLNRKAKELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRS 653
Cdd:pfam02463 169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 654 TQAALDSAYRELTDLHKANAAKDSEVQEAAlrREMKAKEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARK 733
Cdd:pfam02463 249 EQEEIESSKQEIEKEEEKLAQVLKENKEEE--KEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKA 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 734 EDYL---RHEISELQQRLQEAENRNQELSQSVSSTARPLLRQIENLQATLGSQTSSWETLEKSLSDRlgesqtllaaave 810
Cdd:pfam02463 327 EKELkkeKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLK------------- 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 811 reraaTEELLANKIQMSSVESQNTLLRQE---NSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEYVRTLEESRKEKT 887
Cdd:pfam02463 394 -----EEELELKSEEEKEAQLLLELARQLedlLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELK 468
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 124487429 888 LLSSQLEMERMKVEQERKKTIFTQEALKEKDHKLFSVCSTPTMSRSSSISGV 939
Cdd:pfam02463 469 KSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGV 520
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
452-912 |
4.99e-08 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 57.49 E-value: 4.99e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 452 LNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEMKTIKE 531
Cdd:pfam01576 136 LEEDILLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEG 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 532 ELATRlnSSQTADL----------LKEKDEQIQGLMeegEKLSKQQLHNSNIIKKLRakdkdnenviaKLNRKAKELEEE 601
Cdd:pfam01576 216 ESTDL--QEQIAELqaqiaelraqLAKKEEELQAAL---ARLEEETAQKNNALKKIR-----------ELEAQISELQED 279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 602 LqhlrqvldgkeEVEKQHRENikklnsvVERQEKDLG-RLQVDMDELEEKSRSTQAALD---SAYRELTDLHKA--NAAK 675
Cdd:pfam01576 280 L-----------ESERAARNK-------AEKQRRDLGeELEALKTELEDTLDTTAAQQElrsKREQEVTELKKAleEETR 341
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 676 DSEVQEAALR-REMKAKEELSGALEKAQ------EEARQQQEALVLQVGDLRLALQRAEQAAARKEDYLRHEISELQQRL 748
Cdd:pfam01576 342 SHEAQLQEMRqKHTQALEELTEQLEQAKrnkanlEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARL 421
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 749 QEAENRNQELSQSVSStarpLLRQIENLQATLGSQTSSWETLEK---SLSDRLGESQTLLaaavereraatEELLANKIQ 825
Cdd:pfam01576 422 SESERQRAELAEKLSK----LQSELESVSSLLNEAEGKNIKLSKdvsSLESQLQDTQELL-----------QEETRQKLN 486
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 826 MSSVESQntlLRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEY------VRTLEESRK----EKTLLSSQLEM 895
Cdd:pfam01576 487 LSTRLRQ---LEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLeedagtLEALEEGKKrlqrELEALTQQLEE 563
|
490
....*....|....*...
gi 124487429 896 ERMKVEQ-ERKKTIFTQE 912
Cdd:pfam01576 564 KAAAYDKlEKTKNRLQQE 581
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
572-718 |
6.26e-08 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 56.76 E-value: 6.26e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 572 NIIKKLRA---KDKDN-ENVIAKLNRKAKELEEELQHLRQVLdgkEEVEKQHRENIKKLNSVVERQEKDLGRLQVdmdEL 647
Cdd:PRK00409 502 NIIEEAKKligEDKEKlNELIASLEELERELEQKAEEAEALL---KEAEKLKEELEEKKEKLQEEEDKLLEEAEK---EA 575
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 124487429 648 EEKSRSTQAALDSAYRELTDLHKANAA--KDSEVQEAalRREMKAKEELsgaLEKAQEEARQQQEAlvLQVGD 718
Cdd:PRK00409 576 QQAIKEAKKEADEIIKELRQLQKGGYAsvKAHELIEA--RKRLNKANEK---KEKKKKKQKEKQEE--LKVGD 641
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
472-915 |
7.38e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 57.05 E-value: 7.38e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 472 LLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDA-------AKKEMKTIKEELATRLNSSQTAD 544
Cdd:pfam15921 79 VLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAmadirrrESQSQEDLRNQLQNTVHELEAAK 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 545 LLKEkdEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAK-------------------LNRKAKELEEELQHL 605
Cdd:pfam15921 159 CLKE--DMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKkiyehdsmstmhfrslgsaISKILRELDTEISYL 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 606 R-QVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRL----QVDMDELEEKSRSTQAALDSAYRELTDLHkanaaKDSEVQ 680
Cdd:pfam15921 237 KgRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLisehEVEITGLTEKASSARSQANSIQSQLEIIQ-----EQARNQ 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 681 EAALRREMKAKEELSGALEKAQEEARQQQEALVLQVgDLRLALQRAEQAAARKE-DYLRHEI----SELQQRLQEAENRN 755
Cdd:pfam15921 312 NSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEEL-EKQLVLANSELTEARTErDQFSQESgnldDQLQKLLADLHKRE 390
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 756 QELSQSVSSTARPLLRQIENlqatlgsqTSSWETLEKSLSDRLGESQTLLAAAVERERAATEELlanKIQMSSVESQNTL 835
Cdd:pfam15921 391 KELSLEKEQNKRLWDRDTGN--------SITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQM---ERQMAAIQGKNES 459
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 836 LRQENSrLQAQLESEKNKLRKLEDENSRYQVELENLK----------DEYVRTLEESRKEKTLLSSQL-----EMERMKV 900
Cdd:pfam15921 460 LEKVSS-LTAQLESTKEMLRKVVEELTAKKMTLESSErtvsdltaslQEKERAIEATNAEITKLRSRVdlklqELQHLKN 538
|
490
....*....|....*.
gi 124487429 901 EQERKKTIFTQ-EALK 915
Cdd:pfam15921 539 EGDHLRNVQTEcEALK 554
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
647-872 |
9.47e-08 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 56.46 E-value: 9.47e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 647 LEEksRSTQAALDSAYRELTDLHKA-NAAKDSEVQEAALRREMKAKEELSGALEKAqEEARQQQEALVLQVGDLRLALQR 725
Cdd:COG4913 218 LEE--PDTFEAADALVEHFDDLERAhEALEDAREQIELLEPIRELAERYAAARERL-AELEYLRAALRLWFAQRRLELLE 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 726 AEQAAARKE-DYLRHEISELQQRLQEAENRNQELSQSVSS----TARPLLRQIENLQATLGSQTSSWETLEKSLsDRLGE 800
Cdd:COG4913 295 AELEELRAElARLEAELERLEARLDALREELDELEAQIRGnggdRLEQLEREIERLERELEERERRRARLEALL-AALGL 373
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 124487429 801 SQTLlaaavereraATEELLANKIQmssVESQNTLLRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLK 872
Cdd:COG4913 374 PLPA----------SAEEFAALRAE---AAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLE 432
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
463-702 |
3.07e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 54.00 E-value: 3.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 463 LLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEMKTIKEELATrlNSSQT 542
Cdd:COG4942 15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE--LEKEI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 543 ADLLKEKDEQIQGLMEEGEKLSKQQLHNSNIIKkLRAKD-KDNENVIAKLNRKAKELEEELQHLRQVLDGKEEVEKQHRE 621
Cdd:COG4942 93 AELRAELEAQKEELAELLRALYRLGRQPPLALL-LSPEDfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEA 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 622 NIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKANAAKDSEVQEAALRREMKAKEELSGALEKA 701
Cdd:COG4942 172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAAL 251
|
.
gi 124487429 702 Q 702
Cdd:COG4942 252 K 252
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
517-1048 |
7.85e-07 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 53.51 E-value: 7.85e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 517 KERDAAKKEMKTIKEELATRLNSSQTADLLKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLNRKAK 596
Cdd:TIGR00606 193 QVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIK 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 597 EL---EEELQHLRQVLDGK------------EEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSA 661
Cdd:TIGR00606 273 ALksrKKQMEKDNSELELKmekvfqgtdeqlNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRL 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 662 YRELTDLHKANAAKDSEVQEAALRREMKAKEE---LSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKEDYLR 738
Cdd:TIGR00606 353 QLQADRHQEHIRARDSLIQSLATRLELDGFERgpfSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIR 432
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 739 HEISELQQRLQeaeNRNQELSQSVSSTaRPLLRQIENLQATLGSQTSSWETLEKSLSD--RLGESQTLLAAAVERERAAT 816
Cdd:TIGR00606 433 DEKKGLGRTIE---LKKEILEKKQEEL-KFVIKELQQLEGSSDRILELDQELRKAERElsKAEKNSLTETLKKEVKSLQN 508
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 817 EELLANKIQMSSVESQNTLLRQENSRLQAQLESEK--NKLRKLEDENSRYQVELENL------KDEYVRTLEESRKEKTL 888
Cdd:TIGR00606 509 EKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDkmDKDEQIRKIKSRHSDELTSLlgyfpnKKQLEDWLHSKSKEINQ 588
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 889 LSSQL---EMERMKVEQERKKTIFTQEALKEK----DHKLFSVCSTPTM-------------SRSSSISGVDAAGLQASF 948
Cdd:TIGR00606 589 TRDRLaklNKELASLEQNKNHINNELESKEEQlssyEDKLFDVCGSQDEesdlerlkeeiekSSKQRAMLAGATAVYSQF 668
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 949 LSQDESHDHSFGPMSTSASGSNlyeavrmGAGSSIIENLQSQLKLREGEISHLQLEISNLEKTRSIMseeLVKLTNQNDE 1028
Cdd:TIGR00606 669 ITQLTDENQSCCPVCQRVFQTE-------AELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEM---LGLAPGRQSI 738
|
570 580
....*....|....*....|
gi 124487429 1029 LEEKVKEIPKLRVQLRDLDQ 1048
Cdd:TIGR00606 739 IDLKEKEIPELRNKLQKVNR 758
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
588-780 |
8.69e-07 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 53.10 E-value: 8.69e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 588 IAKLNRKAKELEEELQHLRQ---VLDGKEEvEKQHRENIKKLNSvverqekDLGRLQVDMDELEEKSRSTQAALDSAYRE 664
Cdd:COG3206 184 LPELRKELEEAEAALEEFRQkngLVDLSEE-AKLLLQQLSELES-------QLAEARAELAEAEARLAALRAQLGSGPDA 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 665 LTDLHKANAAKDSEVQEAALRREMKAKEELSG----ALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKEDYLRHE 740
Cdd:COG3206 256 LPELLQSPVIQQLRAQLAELEAELAELSARYTpnhpDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQ 335
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 124487429 741 ISELQQRLQEAENRNQELSQsvsstarpLLRQIENLQATL 780
Cdd:COG3206 336 LAQLEARLAELPELEAELRR--------LEREVEVARELY 367
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
441-1090 |
9.97e-07 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 53.05 E-value: 9.97e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 441 EKEDVCKTVEFLNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERD 520
Cdd:pfam02463 333 EKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLE 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 521 AAKKEMKTIKEELATRLnsSQTADLLKEKDEQIQGLMEEGEKLSKQQLHNsniiKKLRAKDKDNENVIAKLNRKAKELEE 600
Cdd:pfam02463 413 LARQLEDLLKEEKKEEL--EILEEEEESIELKQGKLTEEKEELEKQELKL----LKDELELKKSEDLLKETQLVKLQEQL 486
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 601 ELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKANAAKDSEVQ 680
Cdd:pfam02463 487 ELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKL 566
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 681 EAALRREMKAKEELSGALEKAQEEAR--------------QQQEALVLQVGDLRLALQRAEQAAARKEDYLRHEISELQQ 746
Cdd:pfam02463 567 VRALTELPLGARKLRLLIPKLKLPLKsiavleidpilnlaQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKES 646
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 747 RLQEAENRNQELSQSVSSTARPLLRQIENLQATLGSQTSSWETLEKSLSDRLGESQTLLAAAVERERAATEE---LLANK 823
Cdd:pfam02463 647 GLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEaeeLLADR 726
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 824 IQMSSVESQNTLLRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEYVRTLEESRK----EKTLLSSQLEMERMK 899
Cdd:pfam02463 727 VQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKveeeKEEKLKAQEEELRAL 806
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 900 VEQERKKTIFTQEALKEKDHKLfsvcstptmSRSSSISGVDAAGLQASFLSQDEShdhsfgpmSTSASGSNLYEAVRMGA 979
Cdd:pfam02463 807 EEELKEEAELLEEEQLLIEQEE---------KIKEEELEELALELKEEQKLEKLA--------EEELERLEEEITKEELL 869
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 980 GSSIIENLQSQLKLREGEISHLQLEISNLEKTRSIMSEELVKLTNQNDELEEKVKEIPKLRVQLRDLDQRY--------- 1050
Cdd:pfam02463 870 QELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELlleeadeke 949
|
650 660 670 680
....*....|....*....|....*....|....*....|..
gi 124487429 1051 --NTILQMYGEKAEEAEELRLDLEDVKNMYKTQIDELLRQRL 1090
Cdd:pfam02463 950 keENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYN 991
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
447-721 |
1.24e-06 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 52.71 E-value: 1.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 447 KTVEFLNEKLEKRETQLlslskekallEEAYDNLKDemFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEM 526
Cdd:COG3206 175 KALEFLEEQLPELRKEL----------EEAEAALEE--FRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARL 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 527 KTIKEELATRLNSSQTAdllkEKDEQIQGLMEEGEKLSKQqlhnsniIKKLRAKDKDNENVIAKLNRKAKELEEELQhlr 606
Cdd:COG3206 243 AALRAQLGSGPDALPEL----LQSPVIQQLRAQLAELEAE-------LAELSARYTPNHPDVIALRAQIAALRAQLQ--- 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 607 qvldgkeevekqhrenikklnsvvERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKAnaakdsEVQEAALRR 686
Cdd:COG3206 309 ------------------------QEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPEL------EAELRRLER 358
|
250 260 270
....*....|....*....|....*....|....*
gi 124487429 687 EMKAKEELSGALEKAQEEARQQQEalvLQVGDLRL 721
Cdd:COG3206 359 EVEVARELYESLLQRLEEARLAEA---LTVGNVRV 390
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
454-921 |
1.48e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 52.37 E-value: 1.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 454 EKLEKRETQLLSLSKekalLEEAYDNLKDemfRVKEESSSISSLKDeFTQRIAEAEKKVQLACKERDAAKKEMKTIKEEL 533
Cdd:PRK03918 145 ESREKVVRQILGLDD----YENAYKNLGE---VIKEIKRRIERLEK-FIKRTENIEELIKEKEKELEEVLREINEISSEL 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 534 atrlnssqtadllKEKDEQIQGLMEEGEKLskqqlhnsniiKKLRAKDKDNENVIAKLNRKAKELEEELQHLRQVLDGKE 613
Cdd:PRK03918 217 -------------PELREELEKLEKEVKEL-----------EELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELK 272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 614 EVEKQHRENIKKLNSVVERQEKDLgRLQVDMDELEEKSRSTQAALDSAYRELTDLHKanAAKDSEVQEAALRREMKAKEE 693
Cdd:PRK03918 273 KEIEELEEKVKELKELKEKAEEYI-KLSEFYEEYLDELREIEKRLSRLEEEINGIEE--RIKELEEKEERLEELKKKLKE 349
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 694 LSGALEKAQEEARQQQEALVLQVgdlrlalqRAEQAAARKEDYlrhEISELQQRLQEAENRNQELSQSVSStarpLLRQI 773
Cdd:PRK03918 350 LEKRLEELEERHELYEEAKAKKE--------ELERLKKRLTGL---TPEKLEKELEELEKAKEEIEEEISK----ITARI 414
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 774 ENLQATLGSQTSSWETLEKS----------LSD----RLGESQTLLAAAVERERAATEELLaNKIQMSSVESQNTLLRQE 839
Cdd:PRK03918 415 GELKKEIKELKKAIEELKKAkgkcpvcgreLTEehrkELLEEYTAELKRIEKELKEIEEKE-RKLRKELRELEKVLKKES 493
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 840 ----NSRLQAQLESEKNKLRKLEDEnsryqvELENLKDEYVRTLEESRKEKTLLSSqLEMERMKVEQERKKTIFTQEALK 915
Cdd:PRK03918 494 elikLKELAEQLKELEEKLKKYNLE------ELEKKAEEYEKLKEKLIKLKGEIKS-LKKELEKLEELKKKLAELEKKLD 566
|
....*.
gi 124487429 916 EKDHKL 921
Cdd:PRK03918 567 ELEEEL 572
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
697-916 |
1.62e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 51.69 E-value: 1.62e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 697 ALEKAQEEARQQQEALVLQVGDLRLALQRAEQaaarKEDYLRHEISELQQRLQEAENRNQELSQsvsstarpllrQIENL 776
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKK----EEKALLKQLAALERRIAALARRIRALEQ-----------ELAAL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 777 QATLGSQTSSWETLEKSLSDRLGESQTLLAAAVERERAATEELLANKIQMSSVESQNTLLRQENSRLQAQ---LESEKNK 853
Cdd:COG4942 82 EAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQaeeLRADLAE 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 124487429 854 LRKLEDENSRYQVELENLKDEYV---RTLEESRKEKTLLSSQLEMERMKVEQERKKTIFTQEALKE 916
Cdd:COG4942 162 LAALRAELEAERAELEALLAELEeerAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEA 227
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
596-1067 |
2.52e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 51.69 E-value: 2.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 596 KELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKANAAK 675
Cdd:COG4717 49 ERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 676 DSEVQEAALRREMKAKEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKEDYLRHEISELQQRLQEAENRN 755
Cdd:COG4717 129 PLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRL 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 756 QELSQSVSSTAR---PLLRQIENLQATLGSQTSSwETLEKSLSDRLGESQTLLAAAVERERAATEELLANKIQMssVESQ 832
Cdd:COG4717 209 AELEEELEEAQEeleELEEELEQLENELEAAALE-ERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFL--VLGL 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 833 NTLLRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEYVRTLEESRKEKTLLSSQLE--MERMKVEQERKKTIFT 910
Cdd:COG4717 286 LALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEelQELLREAEELEEELQL 365
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 911 QEALKEKDHKLfsvcstpTMSRSSSISGVDAAGLQASFLSQDESHdhsfgpmstsasgsnlyeavrmgagssiIENLQSQ 990
Cdd:COG4717 366 EELEQEIAALL-------AEAGVEDEEELRAALEQAEEYQELKEE----------------------------LEELEEQ 410
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 124487429 991 LKLREGEISHLqLEISNLEKTRSIMSEELVKLTNQNDELEEKVKEIPKLRVQLRDL--DQRYNTILQMYGEKAEEAEEL 1067
Cdd:COG4717 411 LEELLGELEEL-LEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLeeDGELAELLQELEELKAELREL 488
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
409-918 |
2.75e-06 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 51.75 E-value: 2.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 409 LASPTAGSGGHSASGPATEQCEAVENQPKAPPEKEDVCKTVEFLNEKLEKRETQLLSlskEKALLEEAYDNLKD--EMFR 486
Cdd:pfam10174 92 LLQQDFTTSPVDGEDKFSTPELTEENFRRLQSEHERQAKELFLLRKTLEEMELRIET---QKQTLGARDESIKKllEMLQ 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 487 VKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEMKTIKEELATRL----NSSQTADL----------------- 545
Cdd:pfam10174 169 SKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLREELHRRNqlqpDPAKTKALqtviemkdtkisslern 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 546 LKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLNRKAKELEEELQHLRQVLDGKEEVEKQHRENIKK 625
Cdd:pfam10174 249 IRDLEDEVQMLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKLETLTNQNSDCKQHIEV 328
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 626 LNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKANAAKDSEVQEaaLRREMKAKEELSGALEKAQEEA 705
Cdd:pfam10174 329 LKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRD--LKDMLDVKERKINVLQKKIENL 406
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 706 RQQQEALVLQVGDLR--------------LALQRAEQAAARKE---DYLRHEIS-ELQQRLQEAEN---RNQELSQSVSS 764
Cdd:pfam10174 407 QEQLRDKDKQLAGLKervkslqtdssntdTALTTLEEALSEKEriiERLKEQRErEDRERLEELESlkkENKDLKEKVSA 486
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 765 TARPLLRQ---IENLQATLGSQTSSWE-----------TLEKSLSDRLGESQTLLAAAVERERAATEELLANKIQmsSVE 830
Cdd:pfam10174 487 LQPELTEKessLIDLKEHASSLASSGLkkdsklksleiAVEQKKEECSKLENQLKKAHNAEEAVRTNPEINDRIR--LLE 564
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 831 SQNTLLRQENSRLQAQLESEKNKLRKLEDEnsryqvelENLKDEYVRTLEE--SRKEKTLLSSQLEMERMKVEQERKKTI 908
Cdd:pfam10174 565 QEVARYKEESGKAQAEVERLLGILREVENE--------KNDKDKKIAELESltLRQMKEQNKKVANIKHGQQEMKKKGAQ 636
|
570
....*....|
gi 124487429 909 FTQEALKEKD 918
Cdd:pfam10174 637 LLEEARRRED 646
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
588-763 |
3.61e-06 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 49.54 E-value: 3.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 588 IAKLNRKAKELEEELQHLRQVLDGKEEVEKQHRENIKKLnsvverqEKDLGRLQVDMDELEEKSRSTQAALDSA--YREL 665
Cdd:COG1579 19 LDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDL-------EKEIKRLELEIEEVEARIKKYEEQLGNVrnNKEY 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 666 TdlhkanaakdsevqeaALRREMKAKEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKEDYLRHEISELQ 745
Cdd:COG1579 92 E----------------ALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELE 155
|
170
....*....|....*...
gi 124487429 746 QRLQEAENRNQELSQSVS 763
Cdd:COG1579 156 AELEELEAEREELAAKIP 173
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
517-915 |
4.39e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 50.92 E-value: 4.39e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 517 KERDAAKKEMKTIKEELATRLNSSQTAD-LLKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAkdkdnENVIAKLNRKA 595
Cdd:COG4717 74 KELEEELKEAEEKEEEYAELQEELEELEeELEELEAELEELREELEKLEKLLQLLPLYQELEAL-----EAELAELPERL 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 596 KELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVVER----QEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKA 671
Cdd:COG4717 149 EELEERLEELRELEEELEELEAELAELQEELEELLEQlslaTEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 672 NAAKDSEVQEAALRREMKAKE----------ELSGALEKAQEEARQQQEALVLQVG-----DLRLALQRAEQAAARKEDY 736
Cdd:COG4717 229 LEQLENELEAAALEERLKEARlllliaaallALLGLGGSLLSLILTIAGVLFLVLGllallFLLLAREKASLGKEAEELQ 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 737 LRHEISELQQRLQEAENRNQELSQSVS-STARPLLRQIENLQATLgsqtSSWETLEKSLsdRLGESQTLLAAAVERERAA 815
Cdd:COG4717 309 ALPALEELEEEELEELLAALGLPPDLSpEELLELLDRIEELQELL----REAEELEEEL--QLEELEQEIAALLAEAGVE 382
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 816 TEELLANKIQMSSVESQntlLRQENSRLQAQLESEKNKLRKLEDENSRYQV--ELENLK---DEYVRTLEESRKEKTLLS 890
Cdd:COG4717 383 DEEELRAALEQAEEYQE---LKEELEELEEQLEELLGELEELLEALDEEELeeELEELEeelEELEEELEELREELAELE 459
|
410 420 430
....*....|....*....|....*....|..
gi 124487429 891 SQLEM-------ERMKVEQERKKTIFTQEALK 915
Cdd:COG4717 460 AELEQleedgelAELLQELEELKAELRELAEE 491
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
580-916 |
5.28e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 50.81 E-value: 5.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 580 KDKDNENVIAKLNRKAKELEEELQHLrqvldgkEEVEKQHRENIKKLNSVVERQEKDLGRLqvdmDELEEKSRSTQAALD 659
Cdd:PRK02224 200 EEKDLHERLNGLESELAELDEEIERY-------EEQREQARETRDEADEVLEEHEERREEL----ETLEAEIEDLRETIA 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 660 SAYRELTDLHKANAAKDSEVQE-AALRREMKAKEELSGALEKAQEEARQQQEALVLQVGDlRLALQRAEQAAARKE-DYL 737
Cdd:PRK02224 269 ETEREREELAEEVRDLRERLEElEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRD-RLEECRVAAQAHNEEaESL 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 738 RHEISELQQRLQEAENRNQELSQSVSSTArpllRQIENLQATLGSQTSSWETLEKSLSD---RLGESQTLLaaaverera 814
Cdd:PRK02224 348 REDADDLEERAEELREEAAELESELEEAR----EAVEDRREEIEELEEEIEELRERFGDapvDLGNAEDFL--------- 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 815 atEELLANKIQmssvesqntlLRQENSRLQAQLESEKNKLRK---LEDENSRYQVELENLKDEYVRTLEESRKEKTLLSS 891
Cdd:PRK02224 415 --EELREERDE----------LREREAELEATLRTARERVEEaeaLLEAGKCPECGQPVEGSPHVETIEEDRERVEELEA 482
|
330 340
....*....|....*....|....*
gi 124487429 892 QLEMERMKVEqERKKTIFTQEALKE 916
Cdd:PRK02224 483 ELEDLEEEVE-EVEERLERAEDLVE 506
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
544-911 |
5.89e-06 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 50.82 E-value: 5.89e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 544 DLLKEKDEQIQGLMEEGEKLSKQqlhNSNIIKKLRAKDKDNENVIAKL--NRKAKELEEELQHLRQVLDGKEEVekqhRE 621
Cdd:TIGR01612 1118 DDIKNLDQKIDHHIKALEEIKKK---SENYIDEIKAQINDLEDVADKAisNDDPEEIEKKIENIVTKIDKKKNI----YD 1190
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 622 NIKKLNSVVERQEKD-----------------LGRLQVD-MDELEEKSRSTQAALDSAYRELTDLHKANAAKDSEVQ-EA 682
Cdd:TIGR01612 1191 EIKKLLNEIAEIEKDktsleevkginlsygknLGKLFLEkIDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIENEMGiEM 1270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 683 ALRREMKAKeELSGALEKAQEEARQQQEAlvlQVGDLRLALQRAEQAAARKEDyLRHEISELQQRLQEAENRNQELSQSV 762
Cdd:TIGR01612 1271 DIKAEMETF-NISHDDDKDHHIISKKHDE---NISDIREKSLKIIEDFSEESD-INDIKKELQKNLLDAQKHNSDINLYL 1345
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 763 SSTARPL----LRQIENLQATLGSQTSSWETLEKSLSDRLGESQTLLAAAVERERAAT-----EELLANK-----IQmSS 828
Cdd:TIGR01612 1346 NEIANIYnilkLNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLEEckskiESTLDDKdidecIK-KI 1424
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 829 VESQNTLLRQE---NSRLQAQLESEKNKL---RKLEDENSRYQVELENLKD-----------EYVRTLEESRKEKTllss 891
Cdd:TIGR01612 1425 KELKNHILSEEsniDTYFKNADENNENVLllfKNIEMADNKSQHILKIKKDnatndhdfninELKEHIDKSKGCKD---- 1500
|
410 420
....*....|....*....|
gi 124487429 892 qlEMERMKVEQERKKTIFTQ 911
Cdd:TIGR01612 1501 --EADKNAKAIEKNKELFEQ 1518
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
456-925 |
8.07e-06 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 50.12 E-value: 8.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 456 LEKRETQLLS-LSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEMKTIKE--- 531
Cdd:pfam15921 322 LESTVSQLRSeLREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEqnk 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 532 ------------------ELATRLNSSQTAD-LLKEKDEQIQGLME------EGEKLSKQQLhnSNIIKKLRAKDKDNEN 586
Cdd:pfam15921 402 rlwdrdtgnsitidhlrrELDDRNMEVQRLEaLLKAMKSECQGQMErqmaaiQGKNESLEKV--SSLTAQLESTKEMLRK 479
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 587 VIAKLNRKAKELEEE---LQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELeeksRSTQAALDSAYR 663
Cdd:pfam15921 480 VVEELTAKKMTLESSertVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHL----RNVQTECEALKL 555
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 664 ELTDlhkanaaKDSEVQeaALRREMKAKEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKEDYLRheisE 743
Cdd:pfam15921 556 QMAE-------KDKVIE--ILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIR----E 622
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 744 LQQRLQEAENRNQELSQSVSSTARP----------LLRQIENLQATLGSQTSSWETLEKSLSDRLGESQTLLAAAVERER 813
Cdd:pfam15921 623 LEARVSDLELEKVKLVNAGSERLRAvkdikqerdqLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLK 702
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 814 AATEELLANKIQMSSVESQN-------TLLRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEYVRTLEE---SR 883
Cdd:pfam15921 703 SAQSELEQTRNTLKSMEGSDghamkvaMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQElstVA 782
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 124487429 884 KEKTLLSSQLEMERMKvEQERKKTIFTQEALKEKDHKLFSVC 925
Cdd:pfam15921 783 TEKNKMAGELEVLRSQ-ERRLKEKVANMEVALDKASLQFAEC 823
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
685-921 |
8.20e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 50.07 E-value: 8.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 685 RREMKAKEELsgalekaqEEARQQQEALVLQVGDLRLALQRAEQAAARKEDYLrheisELQQRLQEAENrnQELSQSVSS 764
Cdd:TIGR02169 170 RKKEKALEEL--------EEVEENIERLDLIIDEKRQQLERLRREREKAERYQ-----ALLKEKREYEG--YELLKEKEA 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 765 tarpLLRQIENLQATLGSQTSSWETLEKSLSDRLGES----QTLLAAAVERERAATEELLANKIQMSSVESQNTLLRQEN 840
Cdd:TIGR02169 235 ----LERQKEAIERQLASLEEELEKLTEEISELEKRLeeieQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSI 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 841 SRLQAQLESEKNKLRKLEDENSRYQVELENLKdeyvRTLEESRKEKTLLSSQ-------LEMERMKVEQERKKTIFTQEA 913
Cdd:TIGR02169 311 AEKERELEDAEERLAKLEAEIDKLLAEIEELE----REIEEERKRRDKLTEEyaelkeeLEDLRAELEEVDKEFAETRDE 386
|
....*...
gi 124487429 914 LKEKDHKL 921
Cdd:TIGR02169 387 LKDYREKL 394
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
447-635 |
8.38e-06 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 50.02 E-value: 8.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 447 KTVEFLNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKV---------QLACK 517
Cdd:TIGR04523 482 QNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELnkddfelkkENLEK 561
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 518 ERDAAKKEMKTIKEELATRLNS-SQTADLLKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLNRKAK 596
Cdd:TIGR04523 562 EIDEKNKEIEELKQTQKSLKKKqEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKN 641
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 124487429 597 ELEEELQHLRQVLDG----KEEVEKQHRENIKKLNSVVERQEK 635
Cdd:TIGR04523 642 KLKQEVKQIKETIKEirnkWPEIIKKIKESKTKIDDIIELMKD 684
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
460-711 |
1.05e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 49.06 E-value: 1.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 460 ETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEMKTIKEELATRLNS 539
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 540 SQTAD--------LLKEKDeqIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLNRKAKELEEELQHLRQVLDG 611
Cdd:COG3883 95 LYRSGgsvsyldvLLGSES--FSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAE 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 612 KEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKANAAKDSEVQEAALRREMKAK 691
Cdd:COG3883 173 LEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAA 252
|
250 260
....*....|....*....|
gi 124487429 692 EELSGALEKAQEEARQQQEA 711
Cdd:COG3883 253 GAAGAAAGSAGAAGAAAGAA 272
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
431-915 |
1.48e-05 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 49.33 E-value: 1.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 431 AVENQPKAPPEKEDVCKTVEFLNEKLEKRETQLLSLSKEKalleeayDNLKDEM-FRVKEESSSISSLKDEFTQRIAEAE 509
Cdd:pfam05483 167 SAEKTKKYEYEREETRQVYMDLNNNIEKMILAFEELRVQA-------ENARLEMhFKLKEDHEKIQHLEEEYKKEINDKE 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 510 KKVQLACKERDAAKKEMKTIKEELA-TRLNSSQTADLLKEKDEQIQGLMEEGEKLSKQ----QLHNSNIIKKLRAKDKDN 584
Cdd:pfam05483 240 KQVSLLLIQITEKENKMKDLTFLLEeSRDKANQLEEKTKLQDENLKELIEKKDHLTKElediKMSLQRSMSTQKALEEDL 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 585 ENVIAKLNRKAKELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVV----ERQEKDLGRLQVDMDELEEKSRSTQAAL-- 658
Cdd:pfam05483 320 QIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLrteqQRLEKNEDQLKIITMELQKKSSELEEMTkf 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 659 -DSAYRELTDLHKANAAK----DSEVQEAALRREMKAKE-ELSGALEKAQEE----------ARQQQEALVLQVGDLRLA 722
Cdd:pfam05483 400 kNNKEVELEELKKILAEDekllDEKKQFEKIAEELKGKEqELIFLLQAREKEihdleiqltaIKTSEEHYLKEVEDLKTE 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 723 LQRAEQAAARKEDYLRHEISELQQRLQEAEN------RNQELSQSVSSTARPLLRQIENLQATLGSQTSSWETLEKSLSD 796
Cdd:pfam05483 480 LEKEKLKNIELTAHCDKLLLENKELTQEASDmtlelkKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQ 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 797 RLGESQTLLAAAVERERAATEELLANKIQMSSVESQNTLLR--------------QENSRLQAQLESEKNKLRKLEDENS 862
Cdd:pfam05483 560 KGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKkqienknknieelhQENKALKKKGSAENKQLNAYEIKVN 639
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|...
gi 124487429 863 RYQVELENLKDEYVRTLEESRKEktLLSSQLEMERMKVEQERKKTIfTQEALK 915
Cdd:pfam05483 640 KLELELASAKQKFEEIIDNYQKE--IEDKKISEEKLLEEVEKAKAI-ADEAVK 689
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
531-757 |
1.49e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.14 E-value: 1.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 531 EELATRLNssQTADLLKEKDEQIQGLMEEGEKLSKQQLHNSNIiKKLRAKDKDNENVIAKLNRKAKELEE------ELQH 604
Cdd:COG4913 613 AALEAELA--ELEEELAEAEERLEALEAELDALQERREALQRL-AEYSWDEIDVASAEREIAELEAELERldassdDLAA 689
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 605 LRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKANAAKDsevqeaal 684
Cdd:COG4913 690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGD-------- 761
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 685 RREMKAKEELSGALEKAQEEARQQQEALVLQ-----------VGDLRLALQRAEQAAARKEDYLRHEISELQQRLQEAEN 753
Cdd:COG4913 762 AVERELRENLEERIDALRARLNRAEEELERAmrafnrewpaeTADLDADLESLPEYLALLDRLEEDGLPEYEERFKELLN 841
|
....
gi 124487429 754 RNQE 757
Cdd:COG4913 842 ENSI 845
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
447-1089 |
1.51e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 49.20 E-value: 1.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 447 KTVEFLNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEM 526
Cdd:pfam02463 265 EKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKEL 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 527 KTIKEELATRLNSSQTADLLKEKDEQIQGLMEEGEKLSKQQLHNSNIIK-KLRAKDKDNENVIAKLNRKAKELEEELQHL 605
Cdd:pfam02463 345 KELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKeEELELKSEEEKEAQLLLELARQLEDLLKEE 424
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 606 RQVLDGKEEVE------KQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKS------RSTQAALDSAYRELTDLHKANA 673
Cdd:pfam02463 425 KKEELEILEEEeesielKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKEtqlvklQEQLELLLSRQKLEERSQKESK 504
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 674 AKDSEVQEAALRREMKAKE--ELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKEDYLRHEISELQQRLQEA 751
Cdd:pfam02463 505 ARSGLKVLLALIKDGVGGRiiSAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLI 584
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 752 ENRNQELSQSVSSTARPLLRQIENLQATLGSQTSSWETLEKSLSDRLGESQTLLAAAVERERAATEELLANKIQMSSVES 831
Cdd:pfam02463 585 PKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEV 664
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 832 QNTLLRQENSRLQAQLESEKNKLRKLEDENSRYQVELEnlkdeyvrtLEESRKEKTLLSSQLEMERMK-VEQERKKTIFT 910
Cdd:pfam02463 665 KASLSELTKELLEIQELQEKAESELAKEEILRRQLEIK---------KKEQREKEELKKLKLEAEELLaDRVQEAQDKIN 735
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 911 QEALKEKDHKLFSVCSTPTMSRSSSISGVDAAGLQASFLSQDESHDHSFgpmsTSASGSNLYEAVRmgAGSSIIENLQSQ 990
Cdd:pfam02463 736 EELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTE----KLKVEEEKEEKLK--AQEEELRALEEE 809
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 991 LKLREGEISHLQLEISNLEKTRS-------IMSEELVKLTNQNDELEEKVKEIPKLRVQLRDLDQRYNTILQMYGEKAEE 1063
Cdd:pfam02463 810 LKEEAELLEEEQLLIEQEEKIKEeeleelaLELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELE 889
|
650 660
....*....|....*....|....*.
gi 124487429 1064 AEELRLDLEDVKNMYKTQIDELLRQR 1089
Cdd:pfam02463 890 SKEEKEKEEKKELEEESQKLNLLEEK 915
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
452-777 |
1.58e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 49.20 E-value: 1.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 452 LNEKLEKRETQLLSLSKEKALLEEAYDNLKDEmfRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEMKTIKE 531
Cdd:pfam02463 188 LIIDLEELKLQELKLKEQAKKALEYYQLKEKL--ELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEE 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 532 ELATRLNS-SQTADLLKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLNRKAKELEEELQHLRQVLD 610
Cdd:pfam02463 266 KLAQVLKEnKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELK 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 611 GKEEVEKQHRENIKKLNsvvERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHK-----ANAAKDSEVQEAALR 685
Cdd:pfam02463 346 ELEIKREAEEEEEEELE---KLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEeekeaQLLLELARQLEDLLK 422
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 686 REMKAKEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKED--YLRHEISELQQRLQEAENRNQELSQSVS 763
Cdd:pfam02463 423 EEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDllKETQLVKLQEQLELLLSRQKLEERSQKE 502
|
330
....*....|....
gi 124487429 764 STARPLLRQIENLQ 777
Cdd:pfam02463 503 SKARSGLKVLLALI 516
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
427-906 |
1.62e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 49.29 E-value: 1.62e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 427 EQCEAVENQPKAPPEKEDVCKTVEFLNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMfrvkEESSSISSLKDEFTQRIA 506
Cdd:PRK03918 273 KEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERI----KELEEKEERLEELKKKLK 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 507 EAEKKVQlACKERDAAKKEMKTIKEELaTRLNSsqtadllKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKdkdnen 586
Cdd:PRK03918 349 ELEKRLE-ELEERHELYEEAKAKKEEL-ERLKK-------RLTGLTPEKLEKELEELEKAKEEIEEEISKITAR------ 413
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 587 vIAKLNRKAKELEEELQHLRQVlDGK-----EEVEKQHRENIKklnsvvERQEKDLGRLQVDMDELEEKSRSTQAALDSA 661
Cdd:PRK03918 414 -IGELKKEIKELKKAIEELKKA-KGKcpvcgRELTEEHRKELL------EEYTAELKRIEKELKEIEEKERKLRKELREL 485
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 662 YRELTDLHKANAAKDSEVQEAALRREMKA--KEElsgaLEKAQEEARQQQEALVLQVGDLRLALQRAEQAAArkedyLRH 739
Cdd:PRK03918 486 EKVLKKESELIKLKELAEQLKELEEKLKKynLEE----LEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE-----LKK 556
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 740 EISELQQRLQEAENRNQELSQSVSSTARPLLRQIENLQATLGSQTSSWETLeKSLSDRLGESQTLLAAAVERERAATEEL 819
Cdd:PRK03918 557 KLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLEL-KDAEKELEREEKELKKLEEELDKAFEEL 635
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 820 LANKIQMSSVESQNTLLRQENSrlQAQLESEKNKLRKLEDENSRYQVELENLK---DEYVRTLE------ESRKEKTLLS 890
Cdd:PRK03918 636 AETEKRLEELRKELEELEKKYS--EEEYEELREEYLELSRELAGLRAELEELEkrrEEIKKTLEklkeelEEREKAKKEL 713
|
490
....*....|....*.
gi 124487429 891 SQLEMERMKVEQERKK 906
Cdd:PRK03918 714 EKLEKALERVEELREK 729
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
452-1049 |
1.92e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 48.96 E-value: 1.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 452 LNEKLEKRETQLLSLSKEKALLEEAYDNLKDE-MFRVKEESSSISSLKDE-------FTQRIAEAEKKVQLACKERDAAK 523
Cdd:pfam15921 283 LTEKASSARSQANSIQSQLEIIQEQARNQNSMyMRQLSDLESTVSQLRSElreakrmYEDKIEELEKQLVLANSELTEAR 362
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 524 KEMKTIKEELATRlnssqtadllkekDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLNRKAKELEEELQ 603
Cdd:pfam15921 363 TERDQFSQESGNL-------------DDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQ 429
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 604 HLRQVLDG-KEEVEKQHRENIKKLNSVVERQEKdlgrlqvdMDELEEKSRSTQAALDSAYRELTdlHKANAAKDSEVQEA 682
Cdd:pfam15921 430 RLEALLKAmKSECQGQMERQMAAIQGKNESLEK--------VSSLTAQLESTKEMLRKVVEELT--AKKMTLESSERTVS 499
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 683 ALRREMKAKEElsgALEKAQEEARQQQEALVLQVGDLrlalqraeQAAARKEDYLRHEISELQQ-RLQEAENrnqelsqs 761
Cdd:pfam15921 500 DLTASLQEKER---AIEATNAEITKLRSRVDLKLQEL--------QHLKNEGDHLRNVQTECEAlKLQMAEK-------- 560
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 762 vSSTARPLLRQIENLQA-------TLGSQTSSWETLEKSLSDRLGESQTLlaaavereraateELLANKiqmssvesQNT 834
Cdd:pfam15921 561 -DKVIEILRQQIENMTQlvgqhgrTAGAMQVEKAQLEKEINDRRLELQEF-------------KILKDK--------KDA 618
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 835 LLRQENSRLqAQLESEKNKLRKLEDENSRYQVELENLKDEYVRTLEESRKEKTLLSSQLEMERMKVEQERKKTIFTQEAL 914
Cdd:pfam15921 619 KIRELEARV-SDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKL 697
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 915 KekdHKLFSVCSTPTMSRSS--SISGVDAAGLQasflsqdeshdhsfgpmstsasgsnlyeaVRMGagssiienLQSQLK 992
Cdd:pfam15921 698 K---MQLKSAQSELEQTRNTlkSMEGSDGHAMK-----------------------------VAMG--------MQKQIT 737
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 124487429 993 LREGEISHLQLEISNLE-------KTRSIMSEELVKLTNQ----NDELEEKVKEIPKLRVQLRDLDQR 1049
Cdd:pfam15921 738 AKRGQIDALQSKIQFLEeamtnanKEKHFLKEEKNKLSQElstvATEKNKMAGELEVLRSQERRLKEK 805
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
523-894 |
2.14e-05 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 48.42 E-value: 2.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 523 KKEMKTIKEELATRLNSSQTADLLKEKDEQIQGLMEE--GEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLNRKAKELEE 600
Cdd:COG5185 178 KLEIFGLTLGLLKGISELKKAEPSGTVNSIKESETGNlgSESTLLEKAKEIINIEEALKGFQDPESELEDLAQTSDKLEK 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 601 ELQhlrQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALD-SAYRELTDLHKANAAKDSEV 679
Cdd:COG5185 258 LVE---QNTDLRLEKLGENAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESlEEQLAAAEAEQELEESKRET 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 680 QEAALRREMKAKEELSGALEKaQEEARQQQEALVLQVgDLRLALQRAEQAaarkEDYLRHEISELQQRLQEAENRNQELS 759
Cdd:COG5185 335 ETGIQNLTAEIEQGQESLTEN-LEAIKEEIENIVGEV-ELSKSSEELDSF----KDTIESTKESLDEIPQNQRGYAQEIL 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 760 QSVSSTARPLLRQIENLQATLGSQTSSWETLEKSLSDRLGESQTLLAAAVERERAATEEllANKIQMSSVESQNTLLRQE 839
Cdd:COG5185 409 ATLEDTLKAADRQIEELQRQIEQATSSNEEVSKLLNELISELNKVMREADEESQSRLEE--AYDEINRSVRSKKEDLNEE 486
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 124487429 840 NSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEYVRTLEESRKEKTLLSSQLE 894
Cdd:COG5185 487 LTQIESRVSTLKATLEKLRAKLERQLEGVRSKLDQVAESLKDFMRARGYAHILAL 541
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
620-804 |
2.15e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 48.76 E-value: 2.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 620 RENIKKLNSV------VERQEKDLGRLQvdmdELEEKSRSTQAALDSAYRELTDLHKANAAKDSEVQEAALRREMKAKEE 693
Cdd:COG4913 231 VEHFDDLERAhealedAREQIELLEPIR----ELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELAR 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 694 LSGALEKAQEEARQQQEALvlqvgdLRLALQRAEQAAARKEDyLRHEISELQQRLQEAENRNQELSQ-------SVSSTA 766
Cdd:COG4913 307 LEAELERLEARLDALREEL------DELEAQIRGNGGDRLEQ-LEREIERLERELEERERRRARLEAllaalglPLPASA 379
|
170 180 190
....*....|....*....|....*....|....*...
gi 124487429 767 RPLLRQIENLQATLGSQTSSWETLEKSLSDRLGESQTL 804
Cdd:COG4913 380 EEFAALRAEAAALLEALEEELEALEEALAEAEAALRDL 417
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
593-921 |
2.59e-05 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 48.41 E-value: 2.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 593 RKAKELEEE-LQHLRQVLDGKEEVEK----QHRENIKKLNSVVE--RQEKDLGRLQVDMDELEEKSRSTQAALDSAYREL 665
Cdd:PRK04863 299 RRQLAAEQYrLVEMARELAELNEAESdleqDYQAASDHLNLVQTalRQQEKIERYQADLEELEERLEEQNEVVEEADEQQ 378
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 666 TDlhkaNAAKDSEVQEAALRremkAKEELSG---ALEKAQEEARQQQEAL--------VLQVGDLRL--ALQRAEQAAAr 732
Cdd:PRK04863 379 EE----NEARAEAAEEEVDE----LKSQLADyqqALDVQQTRAIQYQQAVqalerakqLCGLPDLTAdnAEDWLEEFQA- 449
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 733 KEDYLRHEISELQQRLQEAENRNQELSQSVSS---------------TARPLLRQIENLQAtLGSQTSSWETLEKSLSDR 797
Cdd:PRK04863 450 KEQEATEELLSLEQKLSVAQAAHSQFEQAYQLvrkiagevsrseawdVARELLRRLREQRH-LAEQLQQLRMRLSELEQR 528
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 798 LGESQTLL-----------------AAAVERERAATEELLANKIQMSSVESQNTLLRQEnsrlQAQLESEKNKLRKLEDE 860
Cdd:PRK04863 529 LRQQQRAErllaefckrlgknlddeDELEQLQEELEARLESLSESVSEARERRMALRQQ----LEQLQARIQRLAARAPA 604
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 124487429 861 NSRYQVELENLKDEYVRTLEESRKEKTLLSSQLEMERmKVEQERKKTIFTQEALKEKDHKL 921
Cdd:PRK04863 605 WLAAQDALARLREQSGEEFEDSQDVTEYMQQLLERER-ELTVERDELAARKQALDEEIERL 664
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
546-733 |
3.45e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 47.85 E-value: 3.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 546 LKEKDEQIQGLMEEGEKLSKQQLHNsniiKKLRAKDKdNENVIAKLNRKAKELEEELQHLRQVLDGKEEVEKQHRENIKK 625
Cdd:PRK12704 33 IKEAEEEAKRILEEAKKEAEAIKKE----ALLEAKEE-IHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEK 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 626 LNSVVERQEKDLGRLQVDMDELEEksrstqaaldsayrELTDLHKANAAKDSEVqeAALRREmKAKEELsgaLEKAQEEA 705
Cdd:PRK12704 108 REEELEKKEKELEQKQQELEKKEE--------------ELEELIEEQLQELERI--SGLTAE-EAKEIL---LEKVEEEA 167
|
170 180
....*....|....*....|....*...
gi 124487429 706 RQQQEALVlqvgdlRLALQRAEQAAARK 733
Cdd:PRK12704 168 RHEAAVLI------KEIEEEAKEEADKK 189
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
480-706 |
4.34e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.60 E-value: 4.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 480 LKDEMFRVKEESSSISSLKDEFT------QRIAEAEKKVQL------ACKERDAAKKEMKTIKEELATR--LNSSQTADL 545
Cdd:COG4913 213 VREYMLEEPDTFEAADALVEHFDdlerahEALEDAREQIELlepireLAERYAAARERLAELEYLRAALrlWFAQRRLEL 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 546 LKEK----DEQIQGLMEEGEKLSKQqlhnsniIKKLRAKDKDNENVIAKL-NRKAKELEEELQHLRQVLDGKEEVEKQHR 620
Cdd:COG4913 293 LEAEleelRAELARLEAELERLEAR-------LDALREELDELEAQIRGNgGDRLEQLEREIERLERELEERERRRARLE 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 621 ENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYREL-TDLHKANAAKDSEVQE-AALRR--------EMKA 690
Cdd:COG4913 366 ALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAeAALRDLRRELRELEAEiASLERrksniparLLAL 445
|
250
....*....|....*.
gi 124487429 691 KEELSGALEKAQEEAR 706
Cdd:COG4913 446 RDALAEALGLDEAELP 461
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
548-910 |
5.94e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 47.04 E-value: 5.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 548 EKDEQIQGLMEEGEKLS----KQQLHNSniiKKLRAKDKDNENVI-AKLNRKAKELEEELQHLRQVlDGKEEVEKQHREN 622
Cdd:pfam17380 294 EKMEQERLRQEKEEKAReverRRKLEEA---EKARQAEMDRQAAIyAEQERMAMERERELERIRQE-ERKRELERIRQEE 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 623 IkklnSVVERQEKDLGRLQVDMDELEEKSRstqaaldsayreltdlHKANAAKDSEVQEAALRREMKAKEELSGALEKAQ 702
Cdd:pfam17380 370 I----AMEISRMRELERLQMERQQKNERVR----------------QELEAARKVKILEEERQRKIQQQKVEMEQIRAEQ 429
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 703 EEARQQQealvlqvgdlrlaLQRAEQAAARKEDYLRHEISELQQ-----RLQEAENRNQELSQSVSSTARPLLRQIENlq 777
Cdd:pfam17380 430 EEARQRE-------------VRRLEEERAREMERVRLEEQERQQqverlRQQEEERKRKKLELEKEKRDRKRAEEQRR-- 494
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 778 atlgsqtsswETLEKSLSDRlgesqtllaaaverERAATEELLANKIQMSSVESQNTLLRQENSRLQAqlESEKNKLRKL 857
Cdd:pfam17380 495 ----------KILEKELEER--------------KQAMIEEERKRKLLEKEMEERQKAIYEEERRREA--EEERRKQQEM 548
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 124487429 858 EdENSRYQVELENLKDEYVRtLEESRKEKTLLSSQLEMERMKVEQERKKTIFT 910
Cdd:pfam17380 549 E-ERRRIQEQMRKATEERSR-LEAMEREREMMRQIVESEKARAEYEATTPITT 599
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
448-878 |
6.47e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.22 E-value: 6.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 448 TVEFLNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEF-TQRIAEAEKKVQLACKERDAAKKEM 526
Cdd:COG4913 282 RLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNgGDRLEQLEREIERLERELEERERRR 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 527 KTIKEELAT-RLNSSQTADLLKEKDEQIQGLMEEGEKLSKQqlhnsniikkLRAKDKDNENVIAKLNRKAKELEEELQHL 605
Cdd:COG4913 362 ARLEALLAAlGLPLPASAEEFAALRAEAAALLEALEEELEA----------LEEALAEAEAALRDLRRELRELEAEIASL 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 606 R-----------------------------------QVLDGKEE-----------------VEKQHrenIKKLNSVVERq 633
Cdd:COG4913 432 ErrksniparllalrdalaealgldeaelpfvgeliEVRPEEERwrgaiervlggfaltllVPPEH---YAAALRWVNR- 507
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 634 EKDLGRLQVD-MDELEEKSRSTQAALDSAYRELT------------------DLHKANAAK------------------- 675
Cdd:COG4913 508 LHLRGRLVYErVRTGLPDPERPRLDPDSLAGKLDfkphpfrawleaelgrrfDYVCVDSPEelrrhpraitragqvkgng 587
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 676 -------------------DSEVQEAALRREMKAKEELSGALEKAQEEARQQQEALVlqvgDLRLALQRAEQAAARKED- 735
Cdd:COG4913 588 trhekddrrrirsryvlgfDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQ----ERREALQRLAEYSWDEIDv 663
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 736 -YLRHEISELQQRLQEAENRNQELSQsvsstarpLLRQIENLQATLGSQTSSWETLE----------KSLSDRLGESQTL 804
Cdd:COG4913 664 aSAEREIAELEAELERLDASSDDLAA--------LEEQLEELEAELEELEEELDELKgeigrlekelEQAEEELDELQDR 735
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 124487429 805 LAAAVERERAATEELLANKIqmssvesQNTLLRQENSRLQAQLESEknkLRKLEDENSRYQVELENLKDEYVRT 878
Cdd:COG4913 736 LEAAEDLARLELRALLEERF-------AAALGDAVERELRENLEER---IDALRARLNRAEEELERAMRAFNRE 799
|
|
| Tropomyosin |
pfam00261 |
Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 ... |
600-800 |
6.61e-05 |
|
Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 parallel helices containing 2 sets of 7 alternating actin binding sites. The protein is best known for its role in regulating the interaction between actin and myosin in muscle contraction, but is also involved in the organization and dynamics of the cytoskeleton in non-muscle cells. There are multiple cell-specific isoforms, expressed by alternative promoters and alternative RNA processing of at least four genes. Muscle isoforms of tropomyosin are characterized by having 284 amino acid residues and a highly conserved N-terminal region, whereas non-muscle forms are generally smaller and are heterogeneous in their N-terminal region.
Pssm-ID: 459736 [Multi-domain] Cd Length: 235 Bit Score: 45.79 E-value: 6.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 600 EELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKAN------- 672
Cdd:pfam00261 1 KKMQQIKEELDEAEERLKEAMKKLEEAEKRAEKAEAEVAALNRRIQLLEEELERTEERLAEALEKLEEAEKAAdesergr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 673 ------AAKDSE--------------VQEAALRREMKAKEEL---SGALEKAQEEARQQQEALVLQVGDLRLA------L 723
Cdd:pfam00261 81 kvlenrALKDEEkmeileaqlkeakeIAEEADRKYEEVARKLvvvEGDLERAEERAELAESKIVELEEELKVVgnnlksL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 124487429 724 QRAEQAAARKEDYLRHEISELQQRLQEAENRNQELSQSVSstarPLLRQIENLQATLGSQTSSWETLEKSLSDRLGE 800
Cdd:pfam00261 161 EASEEKASEREDKYEEQIRFLTEKLKEAETRAEFAERSVQ----KLEKEVDRLEDELEAEKEKYKAISEELDQTLAE 233
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
450-881 |
6.69e-05 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 46.96 E-value: 6.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 450 EFLNEKLEKRETQLLSLSKEK--ALLEEAYDNLKDEmfRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEMK 527
Cdd:PRK02224 275 EELAEEVRDLRERLEELEEERddLLAEAGLDDADAE--AVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDAD 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 528 TIKE------ELATRLNS--SQTADLLKEKDEQIQGLMEEGEKLSKQ------QLHNSNIIKKLRAKDKDN-ENVIAKLN 592
Cdd:PRK02224 353 DLEEraeelrEEAAELESelEEAREAVEDRREEIEELEEEIEELRERfgdapvDLGNAEDFLEELREERDElREREAELE 432
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 593 RKAKELEEELQHLRQVLD-------GKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKsrstqaaldsayrel 665
Cdd:PRK02224 433 ATLRTARERVEEAEALLEagkcpecGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEER--------------- 497
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 666 tdLHKANAAKDSEVQEAALRREMKAKEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKE---DYLRHEIS 742
Cdd:PRK02224 498 --LERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEeeaEEAREEVA 575
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 743 ELQQRLQEAENRNQELSqsvssTARPLLRQIENLQATLGS---QTSSWETLEKSLSDRLGESQTLLAA-AVERERAATEE 818
Cdd:PRK02224 576 ELNSKLAELKERIESLE-----RIRTLLAAIADAEDEIERlreKREALAELNDERRERLAEKRERKRElEAEFDEARIEE 650
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 124487429 819 LLANKIQMSS----VESQNTLLRQENSRLQAQLESEKNKLRKLED-ENSRYQVE-----LENLKDEyVRTLEE 881
Cdd:PRK02224 651 AREDKERAEEyleqVEEKLDELREERDDLQAEIGAVENELEELEElRERREALEnrveaLEALYDE-AEELES 722
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
589-906 |
7.10e-05 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 47.25 E-value: 7.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 589 AKLNRKAKELEEELQ----HLRQVLDGKEEVEK--QHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAY 662
Cdd:COG3096 316 EELSARESDLEQDYQaasdHLNLVQTALRQQEKieRYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLK 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 663 RELTDLHKAnaakdSEVQEaalRREMKAKEELSgALEKAQEearqqqealVLQVGDLRLALQRAEQAAAR-KEDYLRHEI 741
Cdd:COG3096 396 SQLADYQQA-----LDVQQ---TRAIQYQQAVQ-ALEKARA---------LCGLPDLTPENAEDYLAAFRaKEQQATEEV 457
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 742 SELQQRLQEAE-NRNQ-----ELSQSVS---------STARPLLRQIENLQATLGSQtsswETLEKSLSDrlgesqtlla 806
Cdd:COG3096 458 LELEQKLSVADaARRQfekayELVCKIAgeversqawQTARELLRRYRSQQALAQRL----QQLRAQLAE---------- 523
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 807 aavereraaTEELLANkiqmssvesqntllRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEYVRTLEESRKEK 886
Cdd:COG3096 524 ---------LEQRLRQ--------------QQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQR 580
|
330 340
....*....|....*....|
gi 124487429 887 TLLSSQLEMERMKVEQERKK 906
Cdd:COG3096 581 SELRQQLEQLRARIKELAAR 600
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
441-908 |
1.03e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 46.57 E-value: 1.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 441 EKEDVCKTVEFLNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLK---DEFTQRIAEAEKkvqlack 517
Cdd:PRK02224 200 EEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEaeiEDLRETIAETER------- 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 518 ERDAAKKEMKTIKEELATRlnssqtadllkekDEQIQGLMEEGEKLSkqqlhnsniikklrAKDKDNENVIAKLNRKAKE 597
Cdd:PRK02224 273 EREELAEEVRDLRERLEEL-------------EEERDDLLAEAGLDD--------------ADAEAVEARREELEDRDEE 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 598 LEEELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKANAAKDS 677
Cdd:PRK02224 326 LRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPV 405
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 678 EVQEAALRREMKAKE---------ELSGALEKAQEEARQQQEalVLQVGDLRLALQRAEQA--AARKEDYlRHEISELQQ 746
Cdd:PRK02224 406 DLGNAEDFLEELREErdelrereaELEATLRTARERVEEAEA--LLEAGKCPECGQPVEGSphVETIEED-RERVEELEA 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 747 RLQEAENRNQELSQSVSS--TARPLLRQIENLQATLGSQTSSWETLEKSLSDRLGESQTLLAAAVERERAATEELLANKI 824
Cdd:PRK02224 483 ELEDLEEEVEEVEERLERaeDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAE 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 825 QMSSVESQNTLLRQENSRLqAQLESEKNKLRKLEDEnsryQVELENLKDEYVRtLEESRKEKTLLSSQlEMERMKVEQER 904
Cdd:PRK02224 563 AEEEAEEAREEVAELNSKL-AELKERIESLERIRTL----LAAIADAEDEIER-LREKREALAELNDE-RRERLAEKRER 635
|
....
gi 124487429 905 KKTI 908
Cdd:PRK02224 636 KREL 639
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
449-906 |
1.14e-04 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 46.43 E-value: 1.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 449 VEFLNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDE---FTQRIAEAEKKVQLACKERDaakkE 525
Cdd:PRK01156 199 LENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMknrYESEIKTAESDLSMELEKNN----Y 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 526 MKTIKEELATRLNSSQTA------DLLKEKDeQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLNRKakele 599
Cdd:PRK01156 275 YKELEERHMKIINDPVYKnrnyinDYFKYKN-DIENKKQILSNIDAEINKYHAIIKKLSVLQKDYNDYIKKKSRY----- 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 600 EELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYREL--------TDLHKA 671
Cdd:PRK01156 349 DDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEInvklqdisSKVSSL 428
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 672 NAAKDSEVQ-EAALRREMkakEELSG-------ALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKEDYLRHEISe 743
Cdd:PRK01156 429 NQRIRALREnLDELSRNM---EMLNGqsvcpvcGTTLGEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKK- 504
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 744 LQQRLQEAENRNQELSQSVSSTARPLLRQIENLQATLGSQTSSWETLEKSLSdrlgesqtllaaavereRAATEELLANK 823
Cdd:PRK01156 505 RKEYLESEEINKSINEYNKIESARADLEDIKIKINELKDKHDKYEEIKNRYK-----------------SLKLEDLDSKR 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 824 IQMSSVESQNTLLRQENsrLQAQLESEKNKLRKLEDENSRYQVELENLK----------DEYVRTLEESRKEKTLLSSQL 893
Cdd:PRK01156 568 TSWLNALAVISLIDIET--NRSRSNEIKKQLNDLESRLQEIEIGFPDDKsyidksireiENEANNLNNKYNEIQENKILI 645
|
490
....*....|...
gi 124487429 894 EMERMKVEQERKK 906
Cdd:PRK01156 646 EKLRGKIDNYKKQ 658
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
441-710 |
1.25e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 46.19 E-value: 1.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 441 EKEDVCkTVEFLNEKLEKRETQLLSLSKEKALLEEAYDNLKD------EMFRVKEESSSISSLKDEFTQRIAEAEKKVQL 514
Cdd:PRK02224 463 GSPHVE-TIEEDRERVEELEAELEDLEEEVEEVEERLERAEDlveaedRIERLEERREDLEELIAERRETIEEKRERAEE 541
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 515 ACKERDAAKKEMKTIKEELAT-RLNSSQTADLLKEKDEQIQGLMEEGEKLSKqqlhnsniIKKLRAKDKDNENVIAKLNR 593
Cdd:PRK02224 542 LRERAAELEAEAEEKREAAAEaEEEAEEAREEVAELNSKLAELKERIESLER--------IRTLLAAIADAEDEIERLRE 613
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 594 KAKEL----EEELQHLRQVLDGKEEVEKQHREN-IKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDL 668
Cdd:PRK02224 614 KREALaelnDERRERLAEKRERKRELEAEFDEArIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEEL 693
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 124487429 669 hkanaakdsevqeAALRREMKAKEELSGALEKAQEEARQQQE 710
Cdd:PRK02224 694 -------------EELRERREALENRVEALEALYDEAEELES 722
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
544-789 |
1.99e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.21 E-value: 1.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 544 DLLKEKDEQIQGLMEEGEKLSKQqlhnsniIKKLRAKDKDNENVIAKLNRKAKELEEELQHLRQVLDGKEEVEKQHRENI 623
Cdd:COG3883 16 PQIQAKQKELSELQAELEAAQAE-------LDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREEL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 624 KKLNSVVERQEKDLGRLQV-----DMDELEEKSRSTQAALDSAYRELTDLHKANAAKdsEVQEAALRREMKAKEELSGAL 698
Cdd:COG3883 89 GERARALYRSGGSVSYLDVllgseSFSDFLDRLSALSKIADADADLLEELKADKAEL--EAKKAELEAKLAELEALKAEL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 699 EKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKEDYLRHEISELQQRLQEAENRNQELSQSVSSTARPLLRQIENLQA 778
Cdd:COG3883 167 EAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASA 246
|
250
....*....|.
gi 124487429 779 TLGSQTSSWET 789
Cdd:COG3883 247 AGAGAAGAAGA 257
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
719-911 |
2.16e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.39 E-value: 2.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 719 LRLALQRAEQAAARKEDYLRHEISELQQRLQEAEN-----RNQELSQSVSSTARPLLRQIENL-------QATLGSQTSS 786
Cdd:COG3206 162 LEQNLELRREEARKALEFLEEQLPELRKELEEAEAaleefRQKNGLVDLSEEAKLLLQQLSELesqlaeaRAELAEAEAR 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 787 WETLEKSLSDRLGESQTLLAAAVERERAatEELLANKIQMSSVESQNT-------LLRQENSRLQAQLESEKNK-LRKLE 858
Cdd:COG3206 242 LAALRAQLGSGPDALPELLQSPVIQQLR--AQLAELEAELAELSARYTpnhpdviALRAQIAALRAQLQQEAQRiLASLE 319
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 124487429 859 DENSRYQVELENLKDEYVRTLEESrkeKTLLSSQLEMERMKVEQERKKTIFTQ 911
Cdd:COG3206 320 AELEALQAREASLQAQLAQLEARL---AELPELEAELRRLEREVEVARELYES 369
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
441-916 |
2.91e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 45.04 E-value: 2.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 441 EKEDVCKTVEFLNEKLEKRETQLLSLSKEKALLEEAYDNL--KDEMFR-------VKEESSSISSLKDEFTQRIAEAEKK 511
Cdd:TIGR00606 434 EKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRIleLDQELRkaerelsKAEKNSLTETLKKEVKSLQNEKADL 513
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 512 VQLACKErdaaKKEMKTIKEELATRLNSSQTADLLKEKDEQIQGLMEEGEKLSKQQLHN-------SNIIKKLRAKDKDN 584
Cdd:TIGR00606 514 DRKLRKL----DQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYfpnkkqlEDWLHSKSKEINQT 589
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 585 ENVIAKLNRKAKELEEELQHLRQVLDGKEEVEKQHRENIKKLNSvVERQEKDLGRLQVDMdeleEKSRSTQAALdSAYRE 664
Cdd:TIGR00606 590 RDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCG-SQDEESDLERLKEEI----EKSSKQRAML-AGATA 663
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 665 LTDLHKANAAKDSEVQEAALRREMKAKEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKEDYlRHEISEL 744
Cdd:TIGR00606 664 VYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGR-QSIIDLK 742
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 745 QQRLQEAENRNQELSQSVSStarpLLRQIENLQATLGSQTSSWETLEKSLSDrLGESQTLLAAAVERERAAteELLANKI 824
Cdd:TIGR00606 743 EKEIPELRNKLQKVNRDIQR----LKNDIEEQETLLGTIMPEEESAKVCLTD-VTIMERFQMELKDVERKI--AQQAAKL 815
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 825 QMSSVESQNTLLRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDeyvrTLEESRKEKTLLSSQLEMERMKVEQER 904
Cdd:TIGR00606 816 QGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKS----KTNELKSEKLQIGTNLQRRQQFEEQLV 891
|
490
....*....|..
gi 124487429 905 KKTIFTQEALKE 916
Cdd:TIGR00606 892 ELSTEVQSLIRE 903
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
827-1070 |
3.51e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 44.62 E-value: 3.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 827 SSVESQNTLLRQENSRLQAQLESEKNKLRKLEDENSRYQ-----VELENLKDEYVRTLEESRKEKTLLSSQLEMERMKVE 901
Cdd:COG3206 164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRqknglVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLA 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 902 QERKKTIFTQEALkekdhklfsvcstPTMSRSSSISGVDAAGLQASFLSQDEShdhsfgpmstsasgsnlyeaVRMGAGS 981
Cdd:COG3206 244 ALRAQLGSGPDAL-------------PELLQSPVIQQLRAQLAELEAELAELS--------------------ARYTPNH 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 982 SIIENLQSQLKLREGEISH-LQLEISNLEKTRSIMSEELVKLTNQNDELEEKVKEIPKLRVQLRDLDQRYNTILQMYGEK 1060
Cdd:COG3206 291 PDVIALRAQIAALRAQLQQeAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESL 370
|
250
....*....|
gi 124487429 1061 AEEAEELRLD 1070
Cdd:COG3206 371 LQRLEEARLA 380
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
437-566 |
4.33e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 42.99 E-value: 4.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 437 KAPPEKEDVCKTVEFLNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLK---------DEFTQRIAE 507
Cdd:COG1579 28 ELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKeyealqkeiESLKRRISD 107
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 124487429 508 AEKKVQLACKERDAAKKEMKTIKEELATRlnSSQTADLLKEKDEQIQGLMEEGEKLSKQ 566
Cdd:COG1579 108 LEDEILELMERIEELEEELAELEAELAEL--EAELEEKKAELDEELAELEAELEELEAE 164
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
454-799 |
4.59e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 44.56 E-value: 4.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 454 EKLEKRETQLLSLSKE-------KALLEEAYDNLKDEMFRVKE-------ESSSISSLkDEFTQRIAEAEKKVQLACKER 519
Cdd:PRK04863 300 RQLAAEQYRLVEMARElaelneaESDLEQDYQAASDHLNLVQTalrqqekIERYQADL-EELEERLEEQNEVVEEADEQQ 378
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 520 DAAKKEMKTIKEE---LATRLNSSQTA-DLLKEKDEQIQGlmeegeklSKQQLHNSNIIKKLRAKDKDN-ENVIAKLNRK 594
Cdd:PRK04863 379 EENEARAEAAEEEvdeLKSQLADYQQAlDVQQTRAIQYQQ--------AVQALERAKQLCGLPDLTADNaEDWLEEFQAK 450
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 595 AKELEEELQHLRQVLDGKEEVEKQHR---ENIKKLNSVVERQE-------------------KDLGRLQVDMDELEEKSR 652
Cdd:PRK04863 451 EQEATEELLSLEQKLSVAQAAHSQFEqayQLVRKIAGEVSRSEawdvarellrrlreqrhlaEQLQQLRMRLSELEQRLR 530
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 653 StQAALDSAYRELTDLHKANAAKDSEVQEAALRREMkAKEELSGALEKAQE---EARQQQEALVLQVGDLR------LAL 723
Cdd:PRK04863 531 Q-QQRAERLLAEFCKRLGKNLDDEDELEQLQEELEA-RLESLSESVSEARErrmALRQQLEQLQARIQRLAarapawLAA 608
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 724 QRA-----EQAAARKEDylRHEISELQQRLQEAENRNQELSQSVSSTARPLLRQIENLQATLGsqtSSWETLeKSLSDRL 798
Cdd:PRK04863 609 QDAlarlrEQSGEEFED--SQDVTEYMQQLLERERELTVERDELAARKQALDEEIERLSQPGG---SEDPRL-NALAERF 682
|
.
gi 124487429 799 G 799
Cdd:PRK04863 683 G 683
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
579-889 |
4.92e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 44.56 E-value: 4.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 579 AKDKDNENVIAKLNRKAKELEEELQHLRqvldgkeEVEKQHRENIKKLNSVVERQEKDLGRLQV-DMDELEEKSRSTQAA 657
Cdd:COG3096 829 AFAPDPEAELAALRQRRSELERELAQHR-------AQEQQLRQQLDQLKEQLQLLNKLLPQANLlADETLADRLEELREE 901
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 658 LDSAY--RELTDLHKANAAKdSEVQEAALRREMKAKEELSGALEKA---QEEARQQQEALVlQVGDLRLALQRAEQAAAR 732
Cdd:COG3096 902 LDAAQeaQAFIQQHGKALAQ-LEPLVAVLQSDPEQFEQLQADYLQAkeqQRRLKQQIFALS-EVVQRRPHFSYEDAVGLL 979
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 733 KEDylrHEISE-LQQRLQEAEnrnQELSQsvsstARPLLRQIenlQATLGSQTSSWETLEKSLSDRLGESQTLLaaaver 811
Cdd:COG3096 980 GEN---SDLNEkLRARLEQAE---EARRE-----AREQLRQA---QAQYSQYNQVLASLKSSRDAKQQTLQELE------ 1039
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 124487429 812 eraatEELLANKIQMSSvESQNTLlRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEYVRTLEESRKEKTLL 889
Cdd:COG3096 1040 -----QELEELGVQADA-EAEERA-RIRRDELHEELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQV 1110
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
486-799 |
5.00e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 44.56 E-value: 5.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 486 RVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEMKTIKeelatrlnsSQTADLLKEKDEQ----------IQG 555
Cdd:COG3096 351 RYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLK---------SQLADYQQALDVQqtraiqyqqaVQA 421
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 556 LMEEGEKLSKQQLHNSNIikklrakdkdnENVIAKLNRKAKELEEELQHLRQVLDGKEEVEKQHR---ENIKKLNSVVER 632
Cdd:COG3096 422 LEKARALCGLPDLTPENA-----------EDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEkayELVCKIAGEVER 490
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 633 ----------------QEKDLGRLQV---DMDELEEKSRSTQaaldSAYRELTDLHKA-----NAAKDSEVQEAALRREm 688
Cdd:COG3096 491 sqawqtarellrryrsQQALAQRLQQlraQLAELEQRLRQQQ----NAERLLEEFCQRigqqlDAAEELEELLAELEAQ- 565
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 689 kaKEELSGALEKAQEEA---RQQQEALVLQVGDLR------LALQRA-----EQAAARKEDylRHEISELQQRLQEAENR 754
Cdd:COG3096 566 --LEELEEQAAEAVEQRselRQQLEQLRARIKELAarapawLAAQDAlerlrEQSGEALAD--SQEVTAAMQQLLERERE 641
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 124487429 755 NQELSQSVSSTARPLLRQIENLQATLGSQtsswETLEKSLSDRLG 799
Cdd:COG3096 642 ATVERDELAARKQALESQIERLSQPGGAE----DPRLLALAERLG 682
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
698-900 |
5.20e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 44.24 E-value: 5.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 698 LEKAQEEARQQQEALVLQVGDLRLALQRAEQAAAR-KEDY------------------LRHEISELQQRLQEAENRNQEL 758
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEfRQKNglvdlseeaklllqqlseLESQLAEARAELAEAEARLAAL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 759 SQSVSSTARPLLRQIEN-LQATLGSQTSSWETLEKSLSDRLGES----QTLlaaavERERAATEELLANKIQ--MSSVES 831
Cdd:COG3206 246 RAQLGSGPDALPELLQSpVIQQLRAQLAELEAELAELSARYTPNhpdvIAL-----RAQIAALRAQLQQEAQriLASLEA 320
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 124487429 832 QNTLLRQENSRLQAQLESEKNKLRKL---EDENSRYQVELENLKDEYVRTLEesRKEKTLLSSQLEMERMKV 900
Cdd:COG3206 321 ELEALQAREASLQAQLAQLEARLAELpelEAELRRLEREVEVARELYESLLQ--RLEEARLAEALTVGNVRV 390
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
590-912 |
6.61e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.96 E-value: 6.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 590 KLNRKAKELEEELQHLRQVLDGKEEV-EKQHRENIKKLNSVVERQEKD-LGRLQVDMDELEEKSRSTQAALDSayreltd 667
Cdd:pfam17380 259 RYNGQTMTENEFLNQLLHIVQHQKAVsERQQQEKFEKMEQERLRQEKEeKAREVERRRKLEEAEKARQAEMDR------- 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 668 lhkaNAAKDSEVQEAALRREMKAkeELSGALEKAQEEARQQQEALVLQVGDLRlALQRAEQAAARKEDYLRHEI-SELQQ 746
Cdd:pfam17380 332 ----QAAIYAEQERMAMEREREL--ERIRQEERKRELERIRQEEIAMEISRMR-ELERLQMERQQKNERVRQELeAARKV 404
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 747 RLQEAENRnqelsqsvsstaRPLLRQIENLQATLGSQTSSwetlekslsdRLGESQTLLAAAVERERAATEELLANKIQM 826
Cdd:pfam17380 405 KILEEERQ------------RKIQQQKVEMEQIRAEQEEA----------RQREVRRLEEERAREMERVRLEEQERQQQV 462
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 827 SsvesqnTLLRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEYVRTLEESRKEKTLLSSQL--------EMERM 898
Cdd:pfam17380 463 E------RLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEerqkaiyeEERRR 536
|
330
....*....|....
gi 124487429 899 KVEQERKKTIFTQE 912
Cdd:pfam17380 537 EAEEERRKQQEMEE 550
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
450-1088 |
8.30e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 43.42 E-value: 8.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 450 EFLNEKLEKRE---TQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEM 526
Cdd:TIGR00618 156 QFLKAKSKEKKellMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREAL 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 527 KTIKEELA--TRLNSSQTA-----DLLKEKDEQIQGLMEEGEKLSKQQ---------LHNSNIIKKLRAKDKDNENVIAK 590
Cdd:TIGR00618 236 QQTQQSHAylTQKREAQEEqlkkqQLLKQLRARIEELRAQEAVLEETQerinrarkaAPLAAHIKAVTQIEQQAQRIHTE 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 591 LNRKAKELEEELQHLRQVLDGKEEVEKQHR----------------ENIKKLNSVVERQEKDLGRL---QVDMDELEEKS 651
Cdd:TIGR00618 316 LQSKMRSRAKLLMKRAAHVKQQSSIEEQRRllqtlhsqeihirdahEVATSIREISCQQHTLTQHIhtlQQQKTTLTQKL 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 652 RSTQAALDSAYREL-TDLHKANAAKDSEVQEAALRREMKAKEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAA 730
Cdd:TIGR00618 396 QSLCKELDILQREQaTIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQL 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 731 ARKEDYLRHEI---SELQQRLQEAENRNQELSQSVS--STARPLLRQIENLQATLGSQTSSWETLEKSLSDRLGESQTLL 805
Cdd:TIGR00618 476 QTKEQIHLQETrkkAVVLARLLELQEEPCPLCGSCIhpNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSER 555
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 806 AAAVERERAATE---ELLANKIQMSSVESQNTLLRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEYVRTLEES 882
Cdd:TIGR00618 556 KQRASLKEQMQEiqqSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQ 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 883 RKEKTLLSSQLEMERMKV---------------EQERKKTIFTQEALKEKDHKLFSVCST-PTMSRSSSisgvdaagLQA 946
Cdd:TIGR00618 636 QCSQELALKLTALHALQLtltqervrehalsirVLPKELLASRQLALQKMQSEKEQLTYWkEMLAQCQT--------LLR 707
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 947 SFLSQDESHDHSFGPMSTSASGSNLYEAVRMGAGSSIIENLQSQ----LKLREGEISHLQLEISNLEKTRSIMSEELVKL 1022
Cdd:TIGR00618 708 ELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQartvLKARTEAHFNNNEEVTAALQTGAELSHLAAEI 787
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 124487429 1023 TNQNDELEEKVKEIPKLRVQLRDLDQRYNTILQMYGEKAEEAEELRLDLEDVKNMYKTQIDELLRQ 1088
Cdd:TIGR00618 788 QFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLK 853
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
597-868 |
1.13e-03 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 42.81 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 597 ELEEELQHLRQVLDGKEEVEKQHRENIKKLnsvverqEKDLGRLQVDMDELEEKSRSTQAALdSAYRELtdLHKANAAKD 676
Cdd:pfam05557 3 ELIESKARLSQLQNEKKQMELEHKRARIEL-------EKKASALKRQLDRESDRNQELQKRI-RLLEKR--EAEAEEALR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 677 SEVQEAalRREMKAKEELSGAL---EKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKedylRHEISELQQRL----- 748
Cdd:pfam05557 73 EQAELN--RLKKKYLEALNKKLnekESQLADAREVISCLKNELSELRRQIQRAELELQST----NSELEELQERLdllka 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 749 --QEAENRNQELSQSVSSTARPLLRqIENLQATLGSQTSSWETLEKSLSD--RLGESQTLLaaavereraatEELLANKI 824
Cdd:pfam05557 147 kaSEAEQLRQNLEKQQSSLAEAEQR-IKELEFEIQSQEQDSEIVKNSKSElaRIPELEKEL-----------ERLREHNK 214
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 124487429 825 QMSSVESQNTLLRQENSRLQAQLESE---KNKLRKLEDENSRYQVEL 868
Cdd:pfam05557 215 HLNENIENKLLLKEEVEDLKRKLEREekyREEAATLELEKEKLEQEL 261
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
549-902 |
1.13e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 42.96 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 549 KDEQIQGLMEEgeklSKQQLHNsnIIKKLRAKDKDNENVIAKLNRKAKELEEELQHLRQVLDGKEEVEKQHRENIKKLns 628
Cdd:pfam07888 28 RAELLQNRLEE----CLQERAE--LLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEEL-- 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 629 vvERQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKANAAKDSEvQEAALRREMKAKEELSGALEKAQEEARQQ 708
Cdd:pfam07888 100 --EEKYKELSASSEELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLE-RETELERMKERAKKAGAQRKEEEAERKQL 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 709 QEALVLQVGDLR---LALQRAEQAAARKEDY---LRHEISELQQRLQEAENRNQELsqsvsstaRPLLRQIENLQATLGS 782
Cdd:pfam07888 177 QAKLQQTEEELRslsKEFQELRNSLAQRDTQvlqLQDTITTLTQKLTTAHRKEAEN--------EALLEELRSLQERLNA 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 783 QTSSWETLEKSLSDRLGE---SQTLLAAAVERERAATEELLANKIQMSSVESQntlLRQENSRLQAQLESEKNKLRKLED 859
Cdd:pfam07888 249 SERKVEGLGEELSSMAAQrdrTQAELHQARLQAAQLTLQLADASLALREGRAR---WAQERETLQQSAEADKDRIEKLSA 325
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 124487429 860 E--------------NSRYQVELENLKDEYVRTLEESRKEKTLLSSQLEMERMKVEQ 902
Cdd:pfam07888 326 ElqrleerlqeermeREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQ 382
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
452-758 |
1.13e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 43.00 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 452 LNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEMKTIKE 531
Cdd:COG1196 398 LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 532 ELATRLNSSQTADLLKEKDEQIQGLME---EGEKLSKQQLHNSNIIKKL--------------------------RAKDK 582
Cdd:COG1196 478 ALAELLEELAEAAARLLLLLEAEADYEgflEGVKAALLLAGLRGLAGAVavligveaayeaaleaalaaalqnivVEDDE 557
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 583 DNENVIAKLNRKAKELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAY 662
Cdd:COG1196 558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 663 RELTDLH--------------------------KANAAKDSEVQEAALRREMKAKEELSGALEKAQEEARQQQEALVLQV 716
Cdd:COG1196 638 RAVTLAGrlrevtlegeggsaggsltggsrrelLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 124487429 717 GDLRLALQRAEQAAARKEDYLRHE--------------------ISELQQRLQEAENRNQEL 758
Cdd:COG1196 718 EEELEEEALEEQLEAEREELLEELleeeelleeealeelpeppdLEELERELERLEREIEAL 779
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
427-767 |
1.37e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 42.82 E-value: 1.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 427 EQCEAVENQPKAPPEKEDVCKTVEFLNEKLEKRETQLLSLSKEKalleeayDNLKDEMFRVKEESSsissLKDEFTQRIA 506
Cdd:PTZ00121 1561 EEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEE-------KKMKAEEAKKAEEAK----IKAEELKKAE 1629
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 507 EAEKKV-QLACKERDAAKKEMKTIKEELATRLNSSQtadlLKEKDEQIQGLMEEgeklskqqlhnsniIKKLRAKDKDNE 585
Cdd:PTZ00121 1630 EEKKKVeQLKKKEAEEKKKAEELKKAEEENKIKAAE----EAKKAEEDKKKAEE--------------AKKAEEDEKKAA 1691
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 586 NVIAKLNRKAKELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYREL 665
Cdd:PTZ00121 1692 EALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAE 1771
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 666 TDLHKANAAKDSEVQEAALRREMKAKEELSGALEKAQEEARQQQEAlVLQVGDLRLALQRAEQAAARKEDYLRHEISELQ 745
Cdd:PTZ00121 1772 EIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEG-NLVINDSKEMEDSAIKEVADSKNMQLEEADAFE 1850
|
330 340
....*....|....*....|..
gi 124487429 746 QRLQEAENRNQELSQSVSSTAR 767
Cdd:PTZ00121 1851 KHKFNKNNENGEDGNKEADFNK 1872
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
519-796 |
1.61e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 42.58 E-value: 1.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 519 RDAAKKEMKTIKEELATRLNSSQTADLLKEKDEQIQGLMEEGEKLSKQQLhnSNIIKKLRAKDKDnenvIAKLNrkaKEL 598
Cdd:PLN02939 81 RTVMELPQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSKDGEQLSDFQL--EDLVGMIQNAEKN----ILLLN---QAR 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 599 EEELQHLRQVLDGKEEVEK----------QHRENIK---KLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALdsaYREL 665
Cdd:PLN02939 152 LQALEDLEKILTEKEALQGkinilemrlsETDARIKlaaQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSL---SKEL 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 666 TDLHKANA----------AKDSEVQEAALRREMKAKE---------ELSGALEKAQEEARQ----QQEALVLQVGDLRLA 722
Cdd:PLN02939 229 DVLKEENMllkddiqflkAELIEVAETEERVFKLEKErslldaslrELESKFIVAQEDVSKlsplQYDCWWEKVENLQDL 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 723 LQRA----EQAAA---------RKEDYLRHEISE-------------LQQRLQEAENRNQELSQSVSSTARPLLRQIENL 776
Cdd:PLN02939 309 LDRAtnqvEKAALvldqnqdlrDKVDKLEASLKEanvskfssykvelLQQKLKLLEERLQASDHEIHSYIQLYQESIKEF 388
|
330 340
....*....|....*....|..
gi 124487429 777 QATLGS--QTSSWETLEKSLSD 796
Cdd:PLN02939 389 QDTLSKlkEESKKRSLEHPADD 410
|
|
| ATG17_like |
pfam04108 |
Autophagy protein ATG17-like domain; This domain is found in the autophagy-related proteins ... |
534-805 |
1.66e-03 |
|
Autophagy protein ATG17-like domain; This domain is found in the autophagy-related proteins ATG17 and ATG11, conserved across eukaryotes. ATG17 forms a complex with ATG29 and ATG31, critical for both PAS (preautophagosomal structure) formation and autophagy. Together with ATG13, it is required for ATG1 kinase activation. ATG11 is a scaffold protein required for the cytoplasm-to-vacuole targeting (Cvt) pathway during starvation and to recruit ATG proteins to the pre-autophagosome. It is also required for ATG1 kinase activation. In many eukaryotes, ATG11 (the orthologue in mammals is RB1-inducible coiled-coil protein 1 (RB1CC1) and in S. pombe is Taz1-interacting factor 1 (taf1)) is essential for bulk autophagy, except in S.cerevisiae. ATG17 and ATG11 are large similar proteins, both predicted to be almost entirely helical, containing conserved coiled-coil regions and lack obvious functional motifs.
Pssm-ID: 427715 [Multi-domain] Cd Length: 360 Bit Score: 41.99 E-value: 1.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 534 ATRLNSSQTADLLKEKDEQIQGLMEEGEKLSKqqlHNSNIIKKLRAKDKDNENVIAKLNRKAKELEEELQHLRQVLDgkE 613
Cdd:pfam04108 18 DARSLLEELVVLLAKIAFLRRGLSVQLANLEK---VREGLEKVLNELKKDFKQLLKDLDAALERLEETLDKLRNTPV--E 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 614 EVEKQHRENIKKLNSVVERQ--EKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKANAAK----DSEVQEAALRRE 687
Cdd:pfam04108 93 PALPPGEEKQKTLLDFIDEDsvEILRDALKELIDELQAAQESLDSDLKRFDDDLRDLQKELESLsspsESISLIPTLLKE 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 688 MKA-KEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKEDYLRheisELQQRLQEAENRNQELSQSVSS-- 764
Cdd:pfam04108 173 LESlEEEMASLLESLTNHYDQCVTAVKLTEGGRAEMLEVLENDARELDDVVP----ELQDRLDEMENNYERLQKLLEQkn 248
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 124487429 765 ----TARPLLRQIENLQATLGSQTSSWETLEKSLSDRLGESQTLL 805
Cdd:pfam04108 249 slidELLSALQLIAEIQSRLPEYLAALKEFEERWEEEKETIEDYL 293
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
590-878 |
1.75e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 42.31 E-value: 1.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 590 KLNR-KAKELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVverQEKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDL 668
Cdd:PHA02562 170 KLNKdKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKK---NGENIARKQNKYDELVEEAKTIKAEIEELTDELLNL 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 669 hkanaAKDSEVQEAALRREMKAKEELSGALEKAQEEARQQQEAlvlqvGDLRLALQRAEQAAARKEDyLRHEISELQQRL 748
Cdd:PHA02562 247 -----VMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKG-----GVCPTCTQQISEGPDRITK-IKDKLKELQHSL 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 749 QEAENRNQELSQSV------SSTARPLLRQIENLQATLGSQTSSWETLEKslsdrlgesqtllaaavereraateellan 822
Cdd:PHA02562 316 EKLDTAIDELEEIMdefneqSKKLLELKNKISTNKQSLITLVDKAKKVKA------------------------------ 365
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 124487429 823 kiQMSSVESQNTLLRQENSRLQAQLESEKNKLRKLEDENSRYQVELENLKDEYVRT 878
Cdd:PHA02562 366 --AIEELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKYHRGIVTDLLKDSGIKA 419
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
668-851 |
1.88e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.07 E-value: 1.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 668 LHKANAAKDSEVQEAalRREMKAKEELsgALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAARKEDYLRHEISELQQR 747
Cdd:PRK12704 33 IKEAEEEAKRILEEA--KKEAEAIKKE--ALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKR 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 748 LQEAENRNQELSQsvsstarpLLRQIENLQATLgsqtsswETLEKSLSDRLGESQTLlaaavereraATEEllANKIQMS 827
Cdd:PRK12704 109 EEELEKKEKELEQ--------KQQELEKKEEEL-------EELIEEQLQELERISGL----------TAEE--AKEILLE 161
|
170 180 190
....*....|....*....|....*....|
gi 124487429 828 SVESQntlLRQENSRL------QAQLESEK 851
Cdd:PRK12704 162 KVEEE---ARHEAAVLikeieeEAKEEADK 188
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
509-784 |
2.00e-03 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 42.35 E-value: 2.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 509 EKKVQLACKERDAAKKEMKT-IKEELATRLNSSQTADLLKEKDEQIQGLMEEGEKLSKqqlhnsniikKLRAK--DKDNE 585
Cdd:PRK10929 25 EKQITQELEQAKAAKTPAQAeIVEALQSALNWLEERKGSLERAKQYQQVIDNFPKLSA----------ELRQQlnNERDE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 586 NVIAKLNRKAKELEEE-LQHLRQVLDgkeevekQHREnikklnsvvERQEKDLGRLQVD-MDELEEKSRSTQAALDSAYR 663
Cdd:PRK10929 95 PRSVPPNMSTDALEQEiLQVSSQLLE-------KSRQ---------AQQEQDRAREISDsLSQLPQQQTEARRQLNEIER 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 664 ELTDLHKANAAKdSEVQEAALRREMKAKEELSGALEKAQ--------------EEARQQQEALVLQVGDLR--LALQR-- 725
Cdd:PRK10929 159 RLQTLGTPNTPL-AQAQLTALQAESAALKALVDELELAQlsannrqelarlrsELAKKRSQQLDAYLQALRnqLNSQRqr 237
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 726 -AEQAAARKEdYLRHEISELQQRLQEAENRNQELSQSVSSTARPlLRQIENLQATLGSQT 784
Cdd:PRK10929 238 eAERALESTE-LLAEQSGDLPKSIVAQFKINRELSQALNQQAQR-MDLIASQQRQAASQT 295
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
485-708 |
2.11e-03 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 41.94 E-value: 2.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 485 FRVKEESSSISSLKDEFTQRIAEA-----------EKKVQLACKERDAAKKEMKTIKEELATRLNSSQTADLLKEkdeQI 553
Cdd:pfam05667 268 SGASRSAQDLAELLSSFSGSSTTDtgltkgsrfthTEKLQFTNEAPAATSSPPTKVETEEELQQQREEELEELQE---QL 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 554 QGLMEEGEKLSKQqlhnsniIKKLRAKDKDNENVIAKLNRKAKELEEELQHLRQVLDGKEEVEkqhrENIKKLNSVVERQ 633
Cdd:pfam05667 345 EDLESSIQELEKE-------IKKLESSIKQVEEELEELKEQNEELEKQYKVKKKTLDLLPDAE----ENIAKLQALVDAS 413
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 634 EKDLgrlqVDMDELEEKSRstqAALDSAYRELTDLhKANAAKDSEVQEA---ALRREMK-------AKEELSGALEKAQE 703
Cdd:pfam05667 414 AQRL----VELAGQWEKHR---VPLIEEYRALKEA-KSNKEDESQRKLEeikELREKIKevaeeakQKEELYKQLVAEYE 485
|
....*
gi 124487429 704 EARQQ 708
Cdd:pfam05667 486 RLPKD 490
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
498-918 |
2.17e-03 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 41.98 E-value: 2.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 498 KDEFTQRIAEAEKKVQLACKERDAAKKEMKTIKEELATRLNSSQTADLLKEKDEQIQGLMEEgekLSKQQLHNSNIIKKL 577
Cdd:pfam05622 9 KDELAQRCHELDQQVSLLQEEKNSLQQENKKLQERLDQLESGDDSGTPGGKKYLLLQKQLEQ---LQEENFRLETARDDY 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 578 RAKDKDNENVIAKLNRKAKELE---EELQHLRQVLDgkeeVEKQHRENIKKLNSVVERQEK---DLGRLQVDMDELEEKS 651
Cdd:pfam05622 86 RIKCEELEKEVLELQHRNEELTslaEEAQALKDEMD----ILRESSDKVKKLEATVETYKKkleDLGDLRRQVKLLEERN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 652 rstqaaldSAYRELT-----DLHKANAAKDS-EVQEAALRREMKAKEELSGALEKAQEEARQQQEALvlqvgdlrLALQR 725
Cdd:pfam05622 162 --------AEYMQRTlqleeELKKANALRGQlETYKRQVQELHGKLSEESKKADKLEFEYKKLEEKL--------EALQK 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 726 AEQAAARKEDYLRHEISEL------QQRLQEAENRNQELSQSVSSTARPLL-----RQIENLQAtlgSQTSSWETLEKSL 794
Cdd:pfam05622 226 EKERLIIERDTLRETNEELrcaqlqQAELSQADALLSPSSDPGDNLAAEIMpaeirEKLIRLQH---ENKMLRLGQEGSY 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 795 SDRLGESQTLLAAavereraateellANKiQMSSVESQNTLLRQENSRLQAQLEsEKNKLRKLEDENSRYQVELENLKDE 874
Cdd:pfam05622 303 RERLTELQQLLED-------------ANR-RKNELETQNRLANQRILELQQQVE-ELQKALQEQGSKAEDSSLLKQKLEE 367
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 124487429 875 YVRTLEESRKEKTLLSSQLEMERMKVEQERKKTIFT-QEALKEKD 918
Cdd:pfam05622 368 HLEKLHEAQSELQKKKEQIEELEPKQDSNLAQKIDElQEALRKKD 412
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
452-859 |
2.43e-03 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 42.04 E-value: 2.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 452 LNEKLEKRETQLLSLSKEKALLEEAYDNLK---DEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLacKERDAAkkEMKT 528
Cdd:pfam05557 116 LRRQIQRAELELQSTNSELEELQERLDLLKakaSEAEQLRQNLEKQQSSLAEAEQRIKELEFEIQS--QEQDSE--IVKN 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 529 IKEELA----------------TRLNSSQ-TADLLKEKDEQIQGLMEEGEK----LSKQQLHNSNIIKKLRAKDK----- 582
Cdd:pfam05557 192 SKSELAripelekelerlrehnKHLNENIeNKLLLKEEVEDLKRKLEREEKyreeAATLELEKEKLEQELQSWVKlaqdt 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 583 -DNENVIAKLNRKAKEL--------------EEELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDEL 647
Cdd:pfam05557 272 gLNLRSPEDLSRRIEQLqqreivlkeensslTSSARQLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLL 351
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 648 EEKSRSTQAALDSAYRELTdLHKANAAKDSEVQEAA-LRREMKAK-EELSGALEKAQEEA---RQQQEALVLQVGDLRLA 722
Cdd:pfam05557 352 TKERDGYRAILESYDKELT-MSNYSPQLLERIEEAEdMTQKMQAHnEEMEAQLSVAEEELggyKQQAQTLERELQALRQQ 430
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 723 LQRAEQAAARKE-DYLRHEISELQQRLQEAENRNQELSqsvSSTARPLLRQIENLQATLGSQTSSWETLEKslSDRLGES 801
Cdd:pfam05557 431 ESLADPSYSKEEvDSLRRKLETLELERQRLREQKNELE---MELERRCLQGDYDPKKTKVLHLSMNPAAEA--YQQRKNQ 505
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 124487429 802 QTLLAAAVERERAATEELLANKIQMSSV-ESQNTLLRQENSRLQAQLESEKNKLRKLED 859
Cdd:pfam05557 506 LEKLQAEIERLKRLLKKLEDDLEQVLRLpETTSTMNFKEVLDLRKELESAELKNQRLKE 564
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
457-665 |
2.68e-03 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 41.99 E-value: 2.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 457 EKRETQLLSLSKEKALLEEAY--DNLKDEMFRVKEESSSISSLKDEFTQRIAEA-EKKVQLACKERdaAKKEMKTikEEL 533
Cdd:COG5022 855 LKAKKRFSLLKKETIYLQSAQrvELAERQLQELKIDVKSISSLKLVNLELESEIiELKKSLSSDLI--ENLEFKT--ELI 930
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 534 AT--RLNSSQTADLLKEKD----EQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLNRKAKELEEELQHLRQ 607
Cdd:COG5022 931 ARlkKLLNNIDLEEGPSIEyvklPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGA 1010
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 608 VLDGKEEVEKQHREN--IKKLNSVVERQEKDLGRLQvDMDELEEKSRSTQAALDSAYREL 665
Cdd:COG5022 1011 LQESTKQLKELPVEVaeLQSASKIISSESTELSILK-PLQKLKGLLLLENNQLQARYKAL 1069
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
585-754 |
2.81e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.77 E-value: 2.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 585 ENVIAKLnrKAKELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSayre 664
Cdd:COG2433 379 EEALEEL--IEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSE---- 452
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 665 ltdlhkanaAKDSEVQEAALRREMKAKEELSGALEKAQEEARQQQEAL---VLQVGDLRLALQRAEQAAARK-EDYLRHE 740
Cdd:COG2433 453 ---------ARSEERREIRKDREISRLDREIERLERELEEERERIEELkrkLERLKELWKLEHSGELVPVKVvEKFTKEA 523
|
170
....*....|....
gi 124487429 741 ISELQQRLQEAENR 754
Cdd:COG2433 524 IRRLEEEYGLKEGD 537
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
457-872 |
2.89e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 41.75 E-value: 2.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 457 EKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKdEFTQRIAEAEKKVQLACKERDAAKKEM---KTIKEEL 533
Cdd:pfam12128 426 EQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLE-NFDERIERAREEQEAANAEVERLQSELrqaRKRRDQA 504
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 534 ATRLN-SSQTADLLKEKDEQIQ------------------GLMEE--GEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLN 592
Cdd:pfam12128 505 SEALRqASRRLEERQSALDELElqlfpqagtllhflrkeaPDWEQsiGKVISPELLHRTDLDPEVWDGSVGGELNLYGVK 584
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 593 RKAK------------ELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEK--------------DLGRLQVDMDE 646
Cdd:pfam12128 585 LDLKridvpewaaseeELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASReetfartalknarlDLRRLFDEKQS 664
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 647 LEEK-SRSTQAALDSAYRELTDLhkanaakdsEVQEAALRREMKAkeelsgALEKAQEEAR----QQQEALVLQVGDLRL 721
Cdd:pfam12128 665 EKDKkNKALAERKDSANERLNSL---------EAQLKQLDKKHQA------WLEEQKEQKReartEKQAYWQVVEGALDA 729
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 722 ALQRAEQAAARKEDYLRHEISELQQrlqeaENRNQELSQSVSS-TARPLLRQIEnlqatlgsqtssweTLEKSLSDRLGE 800
Cdd:pfam12128 730 QLALLKAAIAARRSGAKAELKALET-----WYKRDLASLGVDPdVIAKLKREIR--------------TLERKIERIAVR 790
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 124487429 801 SQTLLAAAVERERAATEELLANKIQMSSVESQNTLLRQENSRLQAQLESEKNKLRKLEDENSRYQVEL-ENLK 872
Cdd:pfam12128 791 RQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLsENLR 863
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
454-582 |
3.08e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 41.74 E-value: 3.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 454 EKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEEsssissLKDEFTQRIAEAEKKVQlacKERDAAKKEMKTIKEEL 533
Cdd:PRK00409 523 ASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEK------LQEEEDKLLEEAEKEAQ---QAIKEAKKEADEIIKEL 593
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 124487429 534 ATRLNSSQTADLLKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDK 582
Cdd:PRK00409 594 RQLQKGGYASVKAHELIEARKRLNKANEKKEKKKKKQKEKQEELKVGDE 642
|
|
| PRK05431 |
PRK05431 |
seryl-tRNA synthetase; Provisional |
529-610 |
4.03e-03 |
|
seryl-tRNA synthetase; Provisional
Pssm-ID: 235461 [Multi-domain] Cd Length: 425 Bit Score: 40.82 E-value: 4.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 529 IKEELATRlNSSQTADLLKEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAK---LNRKAKELEEELQHL 605
Cdd:PRK05431 14 VKEALAKR-GFPLDVDELLELDEERRELQTELEELQAERNALSKEIGQAKRKGEDAEALIAEvkeLKEEIKALEAELDEL 92
|
....*
gi 124487429 606 RQVLD 610
Cdd:PRK05431 93 EAELE 97
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
452-625 |
5.48e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.91 E-value: 5.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 452 LNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLAC--KERDAAKKEMKTI 529
Cdd:COG1579 22 LEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRnnKEYEALQKEIESL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 530 KEELAtrlnssqtadllkEKDEQIQGLMEEGEKLSKQQLHNSNIIKKLRAKdkdnenviakLNRKAKELEEELQHLRQVL 609
Cdd:COG1579 102 KRRIS-------------DLEDEILELMERIEELEEELAELEAELAELEAE----------LEEKKAELDEELAELEAEL 158
|
170
....*....|....*.
gi 124487429 610 DGKEEVEKQHRENIKK 625
Cdd:COG1579 159 EELEAEREELAAKIPP 174
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
536-658 |
6.11e-03 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 40.84 E-value: 6.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 536 RLNSSQTADLLKEKDEQIQGLMEEGEKLSKQQlhnsniikklrakDKDNENVIAKLNRKAKELEEELQHLRQvldgKEEV 615
Cdd:COG0542 403 RMEIDSKPEELDELERRLEQLEIEKEALKKEQ-------------DEASFERLAELRDELAELEEELEALKA----RWEA 465
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 124487429 616 EKQHRENIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAAL 658
Cdd:COG0542 466 EKELIEEIQELKEELEQRYGKIPELEKELAELEEELAELAPLL 508
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
455-607 |
6.32e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.52 E-value: 6.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 455 KLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEMKTIK--EE 532
Cdd:COG1579 11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRnnKE 90
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 124487429 533 LATRLNSSQTADLLKEK-DEQIQGLMEEGEKLSKQQlhnSNIIKKLRAKDKDNENVIAKLNRKAKELEEELQHLRQ 607
Cdd:COG1579 91 YEALQKEIESLKRRISDlEDEILELMERIEELEEEL---AELEAELAELEAELEEKKAELDEELAELEAELEELEA 163
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
634-798 |
6.67e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.52 E-value: 6.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 634 EKDLGRLQVDMDELEEKSRSTQAALDSAYRELTDLHKANAAKDSEVQEAALRREmKAKEELSGAleKAQEEArqqqEALV 713
Cdd:COG1579 23 EHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIK-KYEEQLGNV--RNNKEY----EALQ 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 714 LQVGDLRLALQRAEQAAARKEDylrhEISELQQRLQEAENRNQELSQSVSSTARPLLRQIENLQATLGSQTSSWETLEKS 793
Cdd:COG1579 96 KEIESLKRRISDLEDEILELME----RIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAK 171
|
....*
gi 124487429 794 LSDRL 798
Cdd:COG1579 172 IPPEL 176
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
505-731 |
7.09e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 40.20 E-value: 7.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 505 IAEAEKKVQLACKERDAAKKEMKTIKEELATRLNS-SQTADLLKEKDEQIQGLMEEGEKLSKQqlhnsniIKKLRAKDKD 583
Cdd:COG3883 11 PAFADPQIQAKQKELSELQAELEAAQAELDALQAElEELNEEYNELQAELEALQAEIDKLQAE-------IAEAEAEIEE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 584 NENVIAKLNRKAKELEEELQHLRQVLDGKEEVEKQHRenIKKLNSVVERQEKDLGRLQVDMDELEEKSRSTQAALDSAYR 663
Cdd:COG3883 84 RREELGERARALYRSGGSVSYLDVLLGSESFSDFLDR--LSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEA 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 664 ELTDL--HKANAAKDSEVQEAALRREMKAKEELSGALEKAQEEARQQQEALVLQVGDLRLALQRAEQAAA 731
Cdd:COG3883 162 LKAELeaAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAA 231
|
|
| PTZ00399 |
PTZ00399 |
cysteinyl-tRNA-synthetase; Provisional |
458-591 |
7.38e-03 |
|
cysteinyl-tRNA-synthetase; Provisional
Pssm-ID: 240402 [Multi-domain] Cd Length: 651 Bit Score: 40.40 E-value: 7.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 458 KRETQLLSLSKEKALLEEAYDNLKDEM-----FRV--KEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEMKTiK 530
Cdd:PTZ00399 501 KAEMKLISLDKKKKQLLQLCDKLRDEWlpnlgIRIedKPDGPSVWKLDDKEELQREKEEKEALKEQKRLRKLKKQEEK-K 579
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 124487429 531 EELATRLNSSQT--ADLLKEK-------DEQIQGLM-EEGEKLSKQQLhnSNIIKKLRAKDKDNENVIAKL 591
Cdd:PTZ00399 580 KKELEKLEKAKIppAEFFKRQedkysafDETGLPTHdADGEEISKKER--KKLSKEYDKQAKLHEEYLAKG 648
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
446-920 |
8.17e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 40.34 E-value: 8.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 446 CKTVEFLNEKLEKRETQLLSLSKEKALLEEAYDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQlACKERDAAKKE 525
Cdd:TIGR00618 399 CKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQ-SLKEREQQLQT 477
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 526 MKTI-KEELATRLNSSQTADLLKEKDEQIQG----------LMEEGEKLSKQQLHNSNIIKKLRAKDKDNENVIAKLNRK 594
Cdd:TIGR00618 478 KEQIhLQETRKKAVVLARLLELQEEPCPLCGscihpnparqDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQ 557
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 595 AKELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVVERQEKDLGRLqvdmDELEEKSRSTQAALDSAYRELTDLHKANAA 674
Cdd:TIGR00618 558 RASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKL----SEAEDMLACEQHALLRKLQPEQDLQDVRLH 633
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 675 KDSEVQEAALRREMKAKEELSGALEKAQEEARQQQEaLVLQVGDLRLALQRAEQAAARKEDYLRHEISELQQRLQEAENR 754
Cdd:TIGR00618 634 LQQCSQELALKLTALHALQLTLTQERVREHALSIRV-LPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETH 712
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 755 NQELSQSVSSTARPLLRQIENLQATLgsqtsswETLEKSLSDRLGESQTLLAAAVERERAATEELLANkIQMSSVESQnt 834
Cdd:TIGR00618 713 IEEYDREFNEIENASSSLGSDLAARE-------DALNQSLKELMHQARTVLKARTEAHFNNNEEVTAA-LQTGAELSH-- 782
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 835 lLRQENSRLQAQLESEKNKLRKLEDEnsrYQVELENLKDEYVRTLEESRKEKTLLSSQLEMERMKVEQERKKTIFTQEAL 914
Cdd:TIGR00618 783 -LAAEIQFFNRLREEDTHLLKTLEAE---IGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECS 858
|
....*.
gi 124487429 915 KEKDHK 920
Cdd:TIGR00618 859 KQLAQL 864
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
441-914 |
8.86e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 40.42 E-value: 8.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 441 EKEDVCKTVEFLNEKLEKRE------TQLLSLSKEKAlleEAYDNLKDEMFRvkeESSSISSLKDEFTQRiAEAEKKVQL 514
Cdd:TIGR00606 509 EKADLDRKLRKLDQEMEQLNhhtttrTQMEMLTKDKM---DKDEQIRKIKSR---HSDELTSLLGYFPNK-KQLEDWLHS 581
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 515 ACKERDAAKKEMKTIKEELAT-RLNSSQTADLLKEKDEQIQGLMEEGEKLSKQQLHNS---NIIKKLRAKDKDNENVIAK 590
Cdd:TIGR00606 582 KSKEINQTRDRLAKLNKELASlEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESdleRLKEEIEKSSKQRAMLAGA 661
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 591 LNRKAK---ELEEELQHLRQVLDGKEEVEKQHRENIKKLNSVV-------ERQEKDLGRLQVDMDELEEKSRSTQAALDS 660
Cdd:TIGR00606 662 TAVYSQfitQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLrlapdklKSTESELKKKEKRRDEMLGLAPGRQSIIDL 741
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 661 AYRELTDLHKANAAKDSEVQE--------AALRREMKAKEELS-------GALEKAQE-----EARQQQEALVLQVGDLR 720
Cdd:TIGR00606 742 KEKEIPELRNKLQKVNRDIQRlkndieeqETLLGTIMPEEESAkvcltdvTIMERFQMelkdvERKIAQQAAKLQGSDLD 821
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 721 LALQRAEQAAARKEDYLR---HEISELQQRLQEAENRNQELSQSVSSTARPLLRQIENLQATlGSQTSSWETLEKSLSDR 797
Cdd:TIGR00606 822 RTVQQVNQEKQEKQHELDtvvSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRR-QQFEEQLVELSTEVQSL 900
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 798 LGESQTLLAAAVERERAATEELLANKIQMSSVESQNTLLRQENSRLQAQLESE----KNKLRKLEDENSRYQVELENLKD 873
Cdd:TIGR00606 901 IREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIhgymKDIENKIQDGKDDYLKQKETELN 980
|
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 124487429 874 EYVRTLEESRKEKTLLSSQLEMERMKVEQERKKTIFTQEAL 914
Cdd:TIGR00606 981 TVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNL 1021
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
655-757 |
9.18e-03 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 39.56 E-value: 9.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124487429 655 QAALDSAYRELTDLHKA-----NAAKDSEVQEAALRREMKAKEELSGALEKAQEEARQQQEALVLQVGDLRLAL----QR 725
Cdd:PRK09039 52 DSALDRLNSQIAELADLlslerQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQELdsekQV 131
|
90 100 110
....*....|....*....|....*....|....*...
gi 124487429 726 AEQAAARKEDY------LRHEISELQQRLQEAENRNQE 757
Cdd:PRK09039 132 SARALAQVELLnqqiaaLRRQLAALEAALDASEKRDRE 169
|
|
| |
