|
Name |
Accession |
Description |
Interval |
E-value |
| myxo_dep_M36 super family |
cl45606 |
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ... |
440-825 |
3.63e-35 |
|
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes. The actual alignment was detected with superfamily member NF038112:
Pssm-ID: 468355 [Multi-domain] Cd Length: 1597 Bit Score: 145.96 E-value: 3.63e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 440 NQPPVAVVSPQTQELsvPLTSALIDGSQSTD-DTEIVSYHWEEVDGP-------------FLGEEFPADTpilrlsnlvp 505
Cdd:NF038112 1185 NRRPVANAGPDQTVL--ERTTVTLNGSGSFDpDGDPLTYAWTQVSGPavtltgadtatpsFTAPEVTADT---------- 1252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 506 gNYTFRLTITDSDGATNSTTASLVIRDaVDYPPVANAGPNQTITlPQNTIILNGNQSSDDHQIVLYEWF--AGPggeskE 583
Cdd:NF038112 1253 -VLTFQLVVSDGTKTSAPDTVTVLVRN-VNRAPVAVAGAPATVD-ERSTVTLDGSGTDADGDALTYAWTqtSGP-----A 1324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 584 MVMQGAQT-------PYLHLSElqegEYTFQLMVTDSSgQQSTALVAVTVQaENNQAPVAVAGPDKElVFPVQSATLDGS 656
Cdd:NF038112 1325 VTLTGATTatatftaPEVTADT----QLTFTLTVSDGT-ASATDTVTVTVR-NVNRAPVANAGADQT-VDERSTVTLSGS 1397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 657 RSSDDHGIVCYHWEHIRGPsAVEMENVDKAIATVTGLQVG---IYHFRLTVRDQQGLSSTSTLTVAVKKENNSPpRAQAG 733
Cdd:NF038112 1398 ATDPDGDALTYAWTQTAGP-TVTLTGADTATASFTAPEVAadtELTFQLTVSADGQASADVTVTVTVRNVNRAP-VAHAG 1475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 734 GRhVLILPNNSITLDGSRSTDDRGIVSYLWIRDGQSP-------AAGDVIGGSDHRAALQLTnlvegvytFHLLVTDSQG 806
Cdd:NF038112 1476 ES-ITVDEGSTVTLDASATDPDGDTLTYAWTQVAGPSvtltgadSAKLTFTAPEVSADTTLT--------FSLTVTDGSG 1546
|
410
....*....|....*....
gi 124486676 807 ASDSDAATVEVLPDPKKDG 825
Cdd:NF038112 1547 SSGPVVVTVTVKNVNRAPD 1565
|
|
| MANEC super family |
cl06508 |
MANEC domain; This region of similarity, comprising 8 conserved cysteines, is found in the ... |
23-102 |
1.15e-12 |
|
MANEC domain; This region of similarity, comprising 8 conserved cysteines, is found in the N-terminal region of several membrane-associated and extracellular proteins. Although formerly called MANSC (for motif at N terminus with seven cysteines) it has now been renamed by MANEC (motif at N terminus with eight cysteines) by Richard Mitter and Stephen Fitzgerald after the discovery of an eighth conserved cysteine. It is postulated that this domain may play a role in the formation of protein complexes involving various protease activators and inhibitors. The actual alignment was detected with superfamily member smart00765:
Pssm-ID: 471454 Cd Length: 93 Bit Score: 64.78 E-value: 1.15e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 23 QQCSEG-RTYSDAIISPNPETIRIMRV----SQTFSVGDCTAACCDLLTCDLAWWF------EGSCYLVKCMRS--ENCE 89
Cdd:smart00765 4 EDCLGRfRVLENAIIRTEESLSAGARFlkspIAVNTWEDCVRACCSTPNCNLAVFElrredaEGNCYLFNCTYPgkEVCK 83
|
90
....*....|...
gi 124486676 90 prtTGPIRSYLTF 102
Cdd:smart00765 84 ---FKPHEGYTSY 93
|
|
| REJ super family |
cl28747 |
REJ domain; The REJ (Receptor for Egg Jelly) domain is found in PKD1, and the sperm receptor ... |
284-571 |
2.90e-03 |
|
REJ domain; The REJ (Receptor for Egg Jelly) domain is found in PKD1, and the sperm receptor for egg jelly Swiss:Q26627. The function of this domain is unknown. The domain is 600 amino acids long so is probably composed of multiple structural domains. There are six completely conserved cysteine residues that may form disulphide bridges. This region contains tandem PKD-like domains. The actual alignment was detected with superfamily member pfam02010:
Pssm-ID: 366875 [Multi-domain] Cd Length: 448 Bit Score: 41.33 E-value: 2.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 284 NPSPASLESSPATTEKNSNFTVTPRSRKHSTPTFPTS-TVLTGLTPPPwplsptasrTVKALAVSAgDNLVLTLPDREAe 362
Cdd:pfam02010 156 QSTSSSLTIPASTLQANVTYTFKLTVSKGSRNSASTTqTILVVDGNPP---------IIILSCISN-CNRKNNPVDRLV- 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 363 LKASVEPAPPADT-TYSYEWSLMSHPVDFQGKIKQENKPTLHLSQ---------LSVGL-YAFRVAVSSENAFGEGYVNV 431
Cdd:pfam02010 225 LLASTCLNCSSDLsDVTYRWLSLGSENTSLVLDQLNSQTSTGRSGpylvikagvLQSGVsYRFTLIVTVYPGLVSGLASI 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 432 TVmpaaRVNQPP------------VAVVSPQTQ------ELSVPLTSALIDGSQSTDDTE--IVSYHWEEVDGPFLgeeF 491
Cdd:pfam02010 305 SF----ITNAPPtggtcsvtptegTALETKFTVtcqgwtDDDLPLTYQFGDISFREASEEwfLLYEGSSQISISTF---L 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 492 PadtpilrlSNLVPGNYTFRL--TITDSDGATNSTTASLVIRdavdyPPVANAGPNQTITLPQNTiiLNGNQSSDDHQIV 569
Cdd:pfam02010 378 P--------PGLPANDYQVTVvvVVYDSLGAATSVSLTITVT-----PPSSSDELLYFLLGTTSD--LSALLQSGDPQQA 442
|
..
gi 124486676 570 LY 571
Cdd:pfam02010 443 AQ 444
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| myxo_dep_M36 |
NF038112 |
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ... |
440-825 |
3.63e-35 |
|
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.
Pssm-ID: 468355 [Multi-domain] Cd Length: 1597 Bit Score: 145.96 E-value: 3.63e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 440 NQPPVAVVSPQTQELsvPLTSALIDGSQSTD-DTEIVSYHWEEVDGP-------------FLGEEFPADTpilrlsnlvp 505
Cdd:NF038112 1185 NRRPVANAGPDQTVL--ERTTVTLNGSGSFDpDGDPLTYAWTQVSGPavtltgadtatpsFTAPEVTADT---------- 1252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 506 gNYTFRLTITDSDGATNSTTASLVIRDaVDYPPVANAGPNQTITlPQNTIILNGNQSSDDHQIVLYEWF--AGPggeskE 583
Cdd:NF038112 1253 -VLTFQLVVSDGTKTSAPDTVTVLVRN-VNRAPVAVAGAPATVD-ERSTVTLDGSGTDADGDALTYAWTqtSGP-----A 1324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 584 MVMQGAQT-------PYLHLSElqegEYTFQLMVTDSSgQQSTALVAVTVQaENNQAPVAVAGPDKElVFPVQSATLDGS 656
Cdd:NF038112 1325 VTLTGATTatatftaPEVTADT----QLTFTLTVSDGT-ASATDTVTVTVR-NVNRAPVANAGADQT-VDERSTVTLSGS 1397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 657 RSSDDHGIVCYHWEHIRGPsAVEMENVDKAIATVTGLQVG---IYHFRLTVRDQQGLSSTSTLTVAVKKENNSPpRAQAG 733
Cdd:NF038112 1398 ATDPDGDALTYAWTQTAGP-TVTLTGADTATASFTAPEVAadtELTFQLTVSADGQASADVTVTVTVRNVNRAP-VAHAG 1475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 734 GRhVLILPNNSITLDGSRSTDDRGIVSYLWIRDGQSP-------AAGDVIGGSDHRAALQLTnlvegvytFHLLVTDSQG 806
Cdd:NF038112 1476 ES-ITVDEGSTVTLDASATDPDGDTLTYAWTQVAGPSvtltgadSAKLTFTAPEVSADTTLT--------FSLTVTDGSG 1546
|
410
....*....|....*....
gi 124486676 807 ASDSDAATVEVLPDPKKDG 825
Cdd:NF038112 1547 SSGPVVVTVTVKNVNRAPD 1565
|
|
| myxo_dep_M36 |
NF038112 |
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ... |
429-741 |
2.71e-32 |
|
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.
Pssm-ID: 468355 [Multi-domain] Cd Length: 1597 Bit Score: 136.71 E-value: 2.71e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 429 VNVTVmpaARVNQPPVAVVS-PQTQELSVPLTsalIDGSQSTDDTEIVSYHWEEVDGP-------------FLGEEFPAD 494
Cdd:NF038112 1272 VTVLV---RNVNRAPVAVAGaPATVDERSTVT---LDGSGTDADGDALTYAWTQTSGPavtltgattatatFTAPEVTAD 1345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 495 TPIlrlsnlvpgnyTFRLTITDSdGATNSTTASLVIRDaVDYPPVANAGPNQTITlPQNTIILNGNQSSDDHQIVLYEWF 574
Cdd:NF038112 1346 TQL-----------TFTLTVSDG-TASATDTVTVTVRN-VNRAPVANAGADQTVD-ERSTVTLSGSATDPDGDALTYAWT 1411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 575 --AGPGGEskemvMQGAQTPYLHL---SELQEGEYTFQLMVTdsSGQQSTALVAVTVQAEN-NQAPVAVAGPDKElVFPV 648
Cdd:NF038112 1412 qtAGPTVT-----LTGADTATASFtapEVAADTELTFQLTVS--ADGQASADVTVTVTVRNvNRAPVAHAGESIT-VDEG 1483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 649 QSATLDGSRSSDDHGIVCYHWEHIRGPSaVEMENVDKAIATVTGLQVG---IYHFRLTVRDQQGLSSTSTLTVAVKKENN 725
Cdd:NF038112 1484 STVTLDASATDPDGDTLTYAWTQVAGPS-VTLTGADSAKLTFTAPEVSadtTLTFSLTVTDGSGSSGPVVVTVTVKNVNR 1562
|
330
....*....|....*....
gi 124486676 726 SPPR---AQAGGRHVLILP 741
Cdd:NF038112 1563 APDGggcSSTGGSPGGMLP 1581
|
|
| MANEC |
smart00765 |
The MANEC domain, formerly called MANSC; This domain, comprising 8 conserved cysteines, is ... |
23-102 |
1.15e-12 |
|
The MANEC domain, formerly called MANSC; This domain, comprising 8 conserved cysteines, is found in the N terminus of higher multicellular animal membrane and extracellular proteins. It is postulated that this domain may play a role in the formation of protein complexes involving various protease activators and inhibitors. It is possible that some of the cysteine residues in the MANSC domain form structurally important disulfide bridges. All of the MANSC-containing proteins contain predicted transmembrane regions and signal peptides. It has been proposed that the MANSC domain in HAI-1 might function through binding with hepatocyte growth factor activator and matriptase.
Pssm-ID: 129004 Cd Length: 93 Bit Score: 64.78 E-value: 1.15e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 23 QQCSEG-RTYSDAIISPNPETIRIMRV----SQTFSVGDCTAACCDLLTCDLAWWF------EGSCYLVKCMRS--ENCE 89
Cdd:smart00765 4 EDCLGRfRVLENAIIRTEESLSAGARFlkspIAVNTWEDCVRACCSTPNCNLAVFElrredaEGNCYLFNCTYPgkEVCK 83
|
90
....*....|...
gi 124486676 90 prtTGPIRSYLTF 102
Cdd:smart00765 84 ---FKPHEGYTSY 93
|
|
| REJ |
pfam02010 |
REJ domain; The REJ (Receptor for Egg Jelly) domain is found in PKD1, and the sperm receptor ... |
379-618 |
4.10e-08 |
|
REJ domain; The REJ (Receptor for Egg Jelly) domain is found in PKD1, and the sperm receptor for egg jelly Swiss:Q26627. The function of this domain is unknown. The domain is 600 amino acids long so is probably composed of multiple structural domains. There are six completely conserved cysteine residues that may form disulphide bridges. This region contains tandem PKD-like domains.
Pssm-ID: 366875 [Multi-domain] Cd Length: 448 Bit Score: 57.13 E-value: 4.10e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 379 YEWSLMSHPVDFqGKIKQENKPTLHLSQ-------LSVGLYAFRVAVSSE---NAFGEGYVNVTVMPAarvnqPPVAVVS 448
Cdd:pfam02010 16 YLWSVFTVSSNL-NLQTISSPKDLVLPQltipsgtLPYGTYVFTLTVSLSstpSLAGTDIITVTVQPS-----PLVAVID 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 449 PQTqELSVPLTSALI-DGSQSTD------DTEIVSYHWEEVDGPFL--------GEEFPADTPILRL-----------SN 502
Cdd:pfam02010 90 GGS-SRVVGYNQDLTlDGSESYDpdvdpgSSSGLTYLWSCRRSSSGdnpllnndPVCFSDQNEGTLLqstsssltipaST 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 503 LVPG-NYTFRLTITDSDGATNSTTASLVIRDavDYPP------VANAgpNQTITLPQNTIILNG--NQSSDDHQIVLYEW 573
Cdd:pfam02010 169 LQANvTYTFKLTVSKGSRNSASTTQTILVVD--GNPPiiilscISNC--NRKNNPVDRLVLLAStcLNCSSDLSDVTYRW 244
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 124486676 574 FAGPGGESKEM-------VMQGAQTPYLHLSE--LQEG-EYTFQLMVTDSSGQQS 618
Cdd:pfam02010 245 LSLGSENTSLVldqlnsqTSTGRSGPYLVIKAgvLQSGvSYRFTLIVTVYPGLVS 299
|
|
| PKD |
smart00089 |
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 ... |
444-530 |
1.34e-07 |
|
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 protein contains 14 repeats, present elsewhere such as in microbial collagenases.
Pssm-ID: 214510 [Multi-domain] Cd Length: 79 Bit Score: 49.76 E-value: 1.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 444 VAVVSPQTQELSVPLTSALIDgsQSTDDTEIVSYHWEEVDGPFLGEefpadtPILRLSNLVPGNYTFRLTITDSDGaTNS 523
Cdd:smart00089 1 VADVSASPTVGVAGESVTFTA--TSSDDGSIVSYTWDFGDGTSSTG------PTVTHTYTKPGTYTVTLTVTNAVG-SAS 71
|
....*..
gi 124486676 524 TTASLVI 530
Cdd:smart00089 72 ATVTVVV 78
|
|
| PKD |
cd00146 |
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an ... |
635-720 |
9.95e-07 |
|
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is presented here. The domain is also found in microbial collagenases and chitinases.
Pssm-ID: 238084 [Multi-domain] Cd Length: 81 Bit Score: 47.49 E-value: 9.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 635 VAVAGPDKELVFPVQSATLDGSrSSDDHGIVCYHWehIRGPSAVEMENVdkAIATVTGLQVGIYHFRLTVRDQQGLSSTS 714
Cdd:cd00146 1 PTASVSAPPVAELGASVTFSAS-DSSGGSIVSYKW--DFGDGEVSSSGE--PTVTHTYTKPGTYTVTLTVTNAVGSSSTK 75
|
....*.
gi 124486676 715 TLTVAV 720
Cdd:cd00146 76 TTTVVV 81
|
|
| REJ |
pfam02010 |
REJ domain; The REJ (Receptor for Egg Jelly) domain is found in PKD1, and the sperm receptor ... |
284-571 |
2.90e-03 |
|
REJ domain; The REJ (Receptor for Egg Jelly) domain is found in PKD1, and the sperm receptor for egg jelly Swiss:Q26627. The function of this domain is unknown. The domain is 600 amino acids long so is probably composed of multiple structural domains. There are six completely conserved cysteine residues that may form disulphide bridges. This region contains tandem PKD-like domains.
Pssm-ID: 366875 [Multi-domain] Cd Length: 448 Bit Score: 41.33 E-value: 2.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 284 NPSPASLESSPATTEKNSNFTVTPRSRKHSTPTFPTS-TVLTGLTPPPwplsptasrTVKALAVSAgDNLVLTLPDREAe 362
Cdd:pfam02010 156 QSTSSSLTIPASTLQANVTYTFKLTVSKGSRNSASTTqTILVVDGNPP---------IIILSCISN-CNRKNNPVDRLV- 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 363 LKASVEPAPPADT-TYSYEWSLMSHPVDFQGKIKQENKPTLHLSQ---------LSVGL-YAFRVAVSSENAFGEGYVNV 431
Cdd:pfam02010 225 LLASTCLNCSSDLsDVTYRWLSLGSENTSLVLDQLNSQTSTGRSGpylvikagvLQSGVsYRFTLIVTVYPGLVSGLASI 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 432 TVmpaaRVNQPP------------VAVVSPQTQ------ELSVPLTSALIDGSQSTDDTE--IVSYHWEEVDGPFLgeeF 491
Cdd:pfam02010 305 SF----ITNAPPtggtcsvtptegTALETKFTVtcqgwtDDDLPLTYQFGDISFREASEEwfLLYEGSSQISISTF---L 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 492 PadtpilrlSNLVPGNYTFRL--TITDSDGATNSTTASLVIRdavdyPPVANAGPNQTITLPQNTiiLNGNQSSDDHQIV 569
Cdd:pfam02010 378 P--------PGLPANDYQVTVvvVVYDSLGAATSVSLTITVT-----PPSSSDELLYFLLGTTSD--LSALLQSGDPQQA 442
|
..
gi 124486676 570 LY 571
Cdd:pfam02010 443 AQ 444
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| myxo_dep_M36 |
NF038112 |
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ... |
440-825 |
3.63e-35 |
|
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.
Pssm-ID: 468355 [Multi-domain] Cd Length: 1597 Bit Score: 145.96 E-value: 3.63e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 440 NQPPVAVVSPQTQELsvPLTSALIDGSQSTD-DTEIVSYHWEEVDGP-------------FLGEEFPADTpilrlsnlvp 505
Cdd:NF038112 1185 NRRPVANAGPDQTVL--ERTTVTLNGSGSFDpDGDPLTYAWTQVSGPavtltgadtatpsFTAPEVTADT---------- 1252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 506 gNYTFRLTITDSDGATNSTTASLVIRDaVDYPPVANAGPNQTITlPQNTIILNGNQSSDDHQIVLYEWF--AGPggeskE 583
Cdd:NF038112 1253 -VLTFQLVVSDGTKTSAPDTVTVLVRN-VNRAPVAVAGAPATVD-ERSTVTLDGSGTDADGDALTYAWTqtSGP-----A 1324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 584 MVMQGAQT-------PYLHLSElqegEYTFQLMVTDSSgQQSTALVAVTVQaENNQAPVAVAGPDKElVFPVQSATLDGS 656
Cdd:NF038112 1325 VTLTGATTatatftaPEVTADT----QLTFTLTVSDGT-ASATDTVTVTVR-NVNRAPVANAGADQT-VDERSTVTLSGS 1397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 657 RSSDDHGIVCYHWEHIRGPsAVEMENVDKAIATVTGLQVG---IYHFRLTVRDQQGLSSTSTLTVAVKKENNSPpRAQAG 733
Cdd:NF038112 1398 ATDPDGDALTYAWTQTAGP-TVTLTGADTATASFTAPEVAadtELTFQLTVSADGQASADVTVTVTVRNVNRAP-VAHAG 1475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 734 GRhVLILPNNSITLDGSRSTDDRGIVSYLWIRDGQSP-------AAGDVIGGSDHRAALQLTnlvegvytFHLLVTDSQG 806
Cdd:NF038112 1476 ES-ITVDEGSTVTLDASATDPDGDTLTYAWTQVAGPSvtltgadSAKLTFTAPEVSADTTLT--------FSLTVTDGSG 1546
|
410
....*....|....*....
gi 124486676 807 ASDSDAATVEVLPDPKKDG 825
Cdd:NF038112 1547 SSGPVVVTVTVKNVNRAPD 1565
|
|
| myxo_dep_M36 |
NF038112 |
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ... |
429-741 |
2.71e-32 |
|
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.
Pssm-ID: 468355 [Multi-domain] Cd Length: 1597 Bit Score: 136.71 E-value: 2.71e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 429 VNVTVmpaARVNQPPVAVVS-PQTQELSVPLTsalIDGSQSTDDTEIVSYHWEEVDGP-------------FLGEEFPAD 494
Cdd:NF038112 1272 VTVLV---RNVNRAPVAVAGaPATVDERSTVT---LDGSGTDADGDALTYAWTQTSGPavtltgattatatFTAPEVTAD 1345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 495 TPIlrlsnlvpgnyTFRLTITDSdGATNSTTASLVIRDaVDYPPVANAGPNQTITlPQNTIILNGNQSSDDHQIVLYEWF 574
Cdd:NF038112 1346 TQL-----------TFTLTVSDG-TASATDTVTVTVRN-VNRAPVANAGADQTVD-ERSTVTLSGSATDPDGDALTYAWT 1411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 575 --AGPGGEskemvMQGAQTPYLHL---SELQEGEYTFQLMVTdsSGQQSTALVAVTVQAEN-NQAPVAVAGPDKElVFPV 648
Cdd:NF038112 1412 qtAGPTVT-----LTGADTATASFtapEVAADTELTFQLTVS--ADGQASADVTVTVTVRNvNRAPVAHAGESIT-VDEG 1483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 649 QSATLDGSRSSDDHGIVCYHWEHIRGPSaVEMENVDKAIATVTGLQVG---IYHFRLTVRDQQGLSSTSTLTVAVKKENN 725
Cdd:NF038112 1484 STVTLDASATDPDGDTLTYAWTQVAGPS-VTLTGADSAKLTFTAPEVSadtTLTFSLTVTDGSGSSGPVVVTVTVKNVNR 1562
|
330
....*....|....*....
gi 124486676 726 SPPR---AQAGGRHVLILP 741
Cdd:NF038112 1563 APDGggcSSTGGSPGGMLP 1581
|
|
| MANEC |
smart00765 |
The MANEC domain, formerly called MANSC; This domain, comprising 8 conserved cysteines, is ... |
23-102 |
1.15e-12 |
|
The MANEC domain, formerly called MANSC; This domain, comprising 8 conserved cysteines, is found in the N terminus of higher multicellular animal membrane and extracellular proteins. It is postulated that this domain may play a role in the formation of protein complexes involving various protease activators and inhibitors. It is possible that some of the cysteine residues in the MANSC domain form structurally important disulfide bridges. All of the MANSC-containing proteins contain predicted transmembrane regions and signal peptides. It has been proposed that the MANSC domain in HAI-1 might function through binding with hepatocyte growth factor activator and matriptase.
Pssm-ID: 129004 Cd Length: 93 Bit Score: 64.78 E-value: 1.15e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 23 QQCSEG-RTYSDAIISPNPETIRIMRV----SQTFSVGDCTAACCDLLTCDLAWWF------EGSCYLVKCMRS--ENCE 89
Cdd:smart00765 4 EDCLGRfRVLENAIIRTEESLSAGARFlkspIAVNTWEDCVRACCSTPNCNLAVFElrredaEGNCYLFNCTYPgkEVCK 83
|
90
....*....|...
gi 124486676 90 prtTGPIRSYLTF 102
Cdd:smart00765 84 ---FKPHEGYTSY 93
|
|
| REJ |
pfam02010 |
REJ domain; The REJ (Receptor for Egg Jelly) domain is found in PKD1, and the sperm receptor ... |
379-618 |
4.10e-08 |
|
REJ domain; The REJ (Receptor for Egg Jelly) domain is found in PKD1, and the sperm receptor for egg jelly Swiss:Q26627. The function of this domain is unknown. The domain is 600 amino acids long so is probably composed of multiple structural domains. There are six completely conserved cysteine residues that may form disulphide bridges. This region contains tandem PKD-like domains.
Pssm-ID: 366875 [Multi-domain] Cd Length: 448 Bit Score: 57.13 E-value: 4.10e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 379 YEWSLMSHPVDFqGKIKQENKPTLHLSQ-------LSVGLYAFRVAVSSE---NAFGEGYVNVTVMPAarvnqPPVAVVS 448
Cdd:pfam02010 16 YLWSVFTVSSNL-NLQTISSPKDLVLPQltipsgtLPYGTYVFTLTVSLSstpSLAGTDIITVTVQPS-----PLVAVID 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 449 PQTqELSVPLTSALI-DGSQSTD------DTEIVSYHWEEVDGPFL--------GEEFPADTPILRL-----------SN 502
Cdd:pfam02010 90 GGS-SRVVGYNQDLTlDGSESYDpdvdpgSSSGLTYLWSCRRSSSGdnpllnndPVCFSDQNEGTLLqstsssltipaST 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 503 LVPG-NYTFRLTITDSDGATNSTTASLVIRDavDYPP------VANAgpNQTITLPQNTIILNG--NQSSDDHQIVLYEW 573
Cdd:pfam02010 169 LQANvTYTFKLTVSKGSRNSASTTQTILVVD--GNPPiiilscISNC--NRKNNPVDRLVLLAStcLNCSSDLSDVTYRW 244
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 124486676 574 FAGPGGESKEM-------VMQGAQTPYLHLSE--LQEG-EYTFQLMVTDSSGQQS 618
Cdd:pfam02010 245 LSLGSENTSLVldqlnsqTSTGRSGPYLVIKAgvLQSGvSYRFTLIVTVYPGLVS 299
|
|
| PKD_4 |
pfam18911 |
PKD domain; This entry is composed of PKD domains found in bacterial surface proteins. |
631-720 |
4.84e-08 |
|
PKD domain; This entry is composed of PKD domains found in bacterial surface proteins.
Pssm-ID: 436824 [Multi-domain] Cd Length: 85 Bit Score: 51.50 E-value: 4.84e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 631 NQAPVAVAGPDKElVFPVQSATLDGSRSSD-DHGIVCYHWEHIRGpSAVEMENVDKAIATvtglqVGIYHFRLTVRDQQG 709
Cdd:pfam18911 1 NAAPVADAGGDRI-VAEGETVTFDASASDDpDGDILSYRWDFGDG-TTATGANVSHTYAA-----PGTYTVTLTVTDDSG 73
|
90
....*....|..
gi 124486676 710 LS-STSTLTVAV 720
Cdd:pfam18911 74 ASnSTATDTVTV 85
|
|
| PKD |
smart00089 |
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 ... |
444-530 |
1.34e-07 |
|
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 protein contains 14 repeats, present elsewhere such as in microbial collagenases.
Pssm-ID: 214510 [Multi-domain] Cd Length: 79 Bit Score: 49.76 E-value: 1.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 444 VAVVSPQTQELSVPLTSALIDgsQSTDDTEIVSYHWEEVDGPFLGEefpadtPILRLSNLVPGNYTFRLTITDSDGaTNS 523
Cdd:smart00089 1 VADVSASPTVGVAGESVTFTA--TSSDDGSIVSYTWDFGDGTSSTG------PTVTHTYTKPGTYTVTLTVTNAVG-SAS 71
|
....*..
gi 124486676 524 TTASLVI 530
Cdd:smart00089 72 ATVTVVV 78
|
|
| PKD |
smart00089 |
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 ... |
635-721 |
1.49e-07 |
|
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 protein contains 14 repeats, present elsewhere such as in microbial collagenases.
Pssm-ID: 214510 [Multi-domain] Cd Length: 79 Bit Score: 49.76 E-value: 1.49e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 635 VAVAGPDKELVFPVQSATLDGSrSSDDHGIVCYHWEHIRGPSAVEmenvdkAIATVTGLQVGIYHFRLTVRDQQGlSSTS 714
Cdd:smart00089 1 VADVSASPTVGVAGESVTFTAT-SSDDGSIVSYTWDFGDGTSSTG------PTVTHTYTKPGTYTVTLTVTNAVG-SASA 72
|
....*..
gi 124486676 715 TLTVAVK 721
Cdd:smart00089 73 TVTVVVQ 79
|
|
| PKD |
cd00146 |
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an ... |
635-720 |
9.95e-07 |
|
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is presented here. The domain is also found in microbial collagenases and chitinases.
Pssm-ID: 238084 [Multi-domain] Cd Length: 81 Bit Score: 47.49 E-value: 9.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 635 VAVAGPDKELVFPVQSATLDGSrSSDDHGIVCYHWehIRGPSAVEMENVdkAIATVTGLQVGIYHFRLTVRDQQGLSSTS 714
Cdd:cd00146 1 PTASVSAPPVAELGASVTFSAS-DSSGGSIVSYKW--DFGDGEVSSSGE--PTVTHTYTKPGTYTVTLTVTNAVGSSSTK 75
|
....*.
gi 124486676 715 TLTVAV 720
Cdd:cd00146 76 TTTVVV 81
|
|
| PKD_4 |
pfam18911 |
PKD domain; This entry is composed of PKD domains found in bacterial surface proteins. |
537-626 |
3.02e-06 |
|
PKD domain; This entry is composed of PKD domains found in bacterial surface proteins.
Pssm-ID: 436824 [Multi-domain] Cd Length: 85 Bit Score: 46.11 E-value: 3.02e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 537 PPVANAGPNQTITLPQnTIILNGNQSSD-DHQIVLYEWFAGPGGESkemvmQGAQTPYLHlseLQEGEYTFQLMVTDSSG 615
Cdd:pfam18911 3 APVADAGGDRIVAEGE-TVTFDASASDDpDGDILSYRWDFGDGTTA-----TGANVSHTY---AAPGTYTVTLTVTDDSG 73
|
90
....*....|..
gi 124486676 616 -QQSTALVAVTV 626
Cdd:pfam18911 74 aSNSTATDTVTV 85
|
|
| REJ |
pfam02010 |
REJ domain; The REJ (Receptor for Egg Jelly) domain is found in PKD1, and the sperm receptor ... |
590-812 |
5.60e-06 |
|
REJ domain; The REJ (Receptor for Egg Jelly) domain is found in PKD1, and the sperm receptor for egg jelly Swiss:Q26627. The function of this domain is unknown. The domain is 600 amino acids long so is probably composed of multiple structural domains. There are six completely conserved cysteine residues that may form disulphide bridges. This region contains tandem PKD-like domains.
Pssm-ID: 366875 [Multi-domain] Cd Length: 448 Bit Score: 50.19 E-value: 5.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 590 QTPYLHLSE--LQEGEYTFQLMVT--DSSGQQSTALVAVTVQAennqAP-VAVAGPDKELVFPVQSA-TLDGSRSSD--- 660
Cdd:pfam02010 39 VLPQLTIPSgtLPYGTYVFTLTVSlsSTPSLAGTDIITVTVQP----SPlVAVIDGGSSRVVGYNQDlTLDGSESYDpdv 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 661 ---DHGIVCYHWEHIRGPSAVE-MENVD----------------KAIATVTG--LQVG-IYHFRLTVRDQQGLSSTSTLT 717
Cdd:pfam02010 115 dpgSSSGLTYLWSCRRSSSGDNpLLNNDpvcfsdqnegtllqstSSSLTIPAstLQANvTYTFKLTVSKGSRNSASTTQT 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 718 VAVKKENnsPPRAqaggrHVLILPNNSITLD--------GSRSTDDRG---IVSYLWIRDG------------QSPAAGD 774
Cdd:pfam02010 195 ILVVDGN--PPII-----ILSCISNCNRKNNpvdrlvllASTCLNCSSdlsDVTYRWLSLGsentslvldqlnSQTSTGR 267
|
250 260 270
....*....|....*....|....*....|....*....
gi 124486676 775 viggSDHRAALQLTNLVEGV-YTFHLLVTDSQGASDSDA 812
Cdd:pfam02010 268 ----SGPYLVIKAGVLQSGVsYRFTLIVTVYPGLVSGLA 302
|
|
| PKD_4 |
pfam18911 |
PKD domain; This entry is composed of PKD domains found in bacterial surface proteins. |
440-524 |
6.11e-06 |
|
PKD domain; This entry is composed of PKD domains found in bacterial surface proteins.
Pssm-ID: 436824 [Multi-domain] Cd Length: 85 Bit Score: 45.34 E-value: 6.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 440 NQPPVAVVSPqTQELSVPLTSALiDGSQSTD-DTEIVSYHWEEVDGPFLGEE-----FPAdtpilrlsnlvPGNYTFRLT 513
Cdd:pfam18911 1 NAAPVADAGG-DRIVAEGETVTF-DASASDDpDGDILSYRWDFGDGTTATGAnvshtYAA-----------PGTYTVTLT 67
|
90
....*....|.
gi 124486676 514 ITDSDGATNST 524
Cdd:pfam18911 68 VTDDSGASNST 78
|
|
| PKD |
cd00146 |
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an ... |
728-817 |
1.36e-05 |
|
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is presented here. The domain is also found in microbial collagenases and chitinases.
Pssm-ID: 238084 [Multi-domain] Cd Length: 81 Bit Score: 44.41 E-value: 1.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 728 PRAQAGGRHVLILpNNSITLDGSRSTDDRgIVSYLWIRDGqspaaGDVIGGSDHRAalQLTNLVEGVYTFHLLVTDSQGA 807
Cdd:cd00146 1 PTASVSAPPVAEL-GASVTFSASDSSGGS-IVSYKWDFGD-----GEVSSSGEPTV--THTYTKPGTYTVTLTVTNAVGS 71
|
90
....*....|
gi 124486676 808 SDSDAATVEV 817
Cdd:cd00146 72 SSTKTTTVVV 81
|
|
| PKD |
cd00146 |
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an ... |
442-530 |
2.51e-05 |
|
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is presented here. The domain is also found in microbial collagenases and chitinases.
Pssm-ID: 238084 [Multi-domain] Cd Length: 81 Bit Score: 43.64 E-value: 2.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 442 PPVAVVSPQTQELSVPLT-SAlidgsQSTDDTEIVSYHWEEVDGPFLGEEfpadTPILRLSNLVPGNYTFRLTITDSDGA 520
Cdd:cd00146 1 PTASVSAPPVAELGASVTfSA-----SDSSGGSIVSYKWDFGDGEVSSSG----EPTVTHTYTKPGTYTVTLTVTNAVGS 71
|
90
....*....|
gi 124486676 521 TNSTTASLVI 530
Cdd:cd00146 72 SSTKTTTVVV 81
|
|
| PKD |
smart00089 |
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 ... |
729-817 |
2.91e-05 |
|
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 protein contains 14 repeats, present elsewhere such as in microbial collagenases.
Pssm-ID: 214510 [Multi-domain] Cd Length: 79 Bit Score: 43.21 E-value: 2.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 729 RAQAGGRHVLILPNNSITLDGSrSTDDRGIVSYLWirdgqspaagDVIGGSDHRAA-LQLTNLVEGVYTFHLLVTDSQGa 807
Cdd:smart00089 1 VADVSASPTVGVAGESVTFTAT-SSDDGSIVSYTW----------DFGDGTSSTGPtVTHTYTKPGTYTVTLTVTNAVG- 68
|
90
....*....|
gi 124486676 808 SDSDAATVEV 817
Cdd:smart00089 69 SASATVTVVV 78
|
|
| PKD_4 |
pfam18911 |
PKD domain; This entry is composed of PKD domains found in bacterial surface proteins. |
725-817 |
1.41e-04 |
|
PKD domain; This entry is composed of PKD domains found in bacterial surface proteins.
Pssm-ID: 436824 [Multi-domain] Cd Length: 85 Bit Score: 41.49 E-value: 1.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 725 NSPPRAQAGGRhVLILPNNSITLDGSRSTD-DRGIVSYLW-IRDGQSPAAGDViggsDHRAAlqltnlVEGVYTFHLLVT 802
Cdd:pfam18911 1 NAAPVADAGGD-RIVAEGETVTFDASASDDpDGDILSYRWdFGDGTTATGANV----SHTYA------APGTYTVTLTVT 69
|
90
....*....|....*.
gi 124486676 803 DSQGASDS-DAATVEV 817
Cdd:pfam18911 70 DDSGASNStATDTVTV 85
|
|
| PKD |
smart00089 |
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 ... |
539-627 |
7.25e-04 |
|
Repeats in polycystic kidney disease 1 (PKD1) and other proteins; Polycystic kidney disease 1 protein contains 14 repeats, present elsewhere such as in microbial collagenases.
Pssm-ID: 214510 [Multi-domain] Cd Length: 79 Bit Score: 39.36 E-value: 7.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 539 VANAGPNQTITLPQNTIILNGnQSSDDHQIVLYEWFAGPGGESKEmvmqgaqtPYLHLSELQEGEYTFQLMVTDSSGqQS 618
Cdd:smart00089 1 VADVSASPTVGVAGESVTFTA-TSSDDGSIVSYTWDFGDGTSSTG--------PTVTHTYTKPGTYTVTLTVTNAVG-SA 70
|
....*....
gi 124486676 619 TALVAVTVQ 627
Cdd:smart00089 71 SATVTVVVQ 79
|
|
| PKD |
cd00146 |
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an ... |
538-626 |
1.32e-03 |
|
polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is presented here. The domain is also found in microbial collagenases and chitinases.
Pssm-ID: 238084 [Multi-domain] Cd Length: 81 Bit Score: 38.63 E-value: 1.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 538 PVANAGPNQTITLPQNtIILNGNqSSDDHQIVLYEWFAGPGGESkemvMQGAQTPylHLSELQEGEYTFQLMVTDSSGQQ 617
Cdd:cd00146 1 PTASVSAPPVAELGAS-VTFSAS-DSSGGSIVSYKWDFGDGEVS----SSGEPTV--THTYTKPGTYTVTLTVTNAVGSS 72
|
....*....
gi 124486676 618 STALVAVTV 626
Cdd:cd00146 73 STKTTTVVV 81
|
|
| REJ |
pfam02010 |
REJ domain; The REJ (Receptor for Egg Jelly) domain is found in PKD1, and the sperm receptor ... |
284-571 |
2.90e-03 |
|
REJ domain; The REJ (Receptor for Egg Jelly) domain is found in PKD1, and the sperm receptor for egg jelly Swiss:Q26627. The function of this domain is unknown. The domain is 600 amino acids long so is probably composed of multiple structural domains. There are six completely conserved cysteine residues that may form disulphide bridges. This region contains tandem PKD-like domains.
Pssm-ID: 366875 [Multi-domain] Cd Length: 448 Bit Score: 41.33 E-value: 2.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 284 NPSPASLESSPATTEKNSNFTVTPRSRKHSTPTFPTS-TVLTGLTPPPwplsptasrTVKALAVSAgDNLVLTLPDREAe 362
Cdd:pfam02010 156 QSTSSSLTIPASTLQANVTYTFKLTVSKGSRNSASTTqTILVVDGNPP---------IIILSCISN-CNRKNNPVDRLV- 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 363 LKASVEPAPPADT-TYSYEWSLMSHPVDFQGKIKQENKPTLHLSQ---------LSVGL-YAFRVAVSSENAFGEGYVNV 431
Cdd:pfam02010 225 LLASTCLNCSSDLsDVTYRWLSLGSENTSLVLDQLNSQTSTGRSGpylvikagvLQSGVsYRFTLIVTVYPGLVSGLASI 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 432 TVmpaaRVNQPP------------VAVVSPQTQ------ELSVPLTSALIDGSQSTDDTE--IVSYHWEEVDGPFLgeeF 491
Cdd:pfam02010 305 SF----ITNAPPtggtcsvtptegTALETKFTVtcqgwtDDDLPLTYQFGDISFREASEEwfLLYEGSSQISISTF---L 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 124486676 492 PadtpilrlSNLVPGNYTFRL--TITDSDGATNSTTASLVIRdavdyPPVANAGPNQTITLPQNTiiLNGNQSSDDHQIV 569
Cdd:pfam02010 378 P--------PGLPANDYQVTVvvVVYDSLGAATSVSLTITVT-----PPSSSDELLYFLLGTTSD--LSALLQSGDPQQA 442
|
..
gi 124486676 570 LY 571
Cdd:pfam02010 443 AQ 444
|
|
|