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Conserved domains on  [gi|575403062|ref|NP_001020530|]
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kinesin light chain 1 isoform 1C [Mus musculus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11419012)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

Gene Ontology:  GO:0005515
PubMed:  10517866|30708253

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
210-435 1.20e-27

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 111.64  E-value: 1.20e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 210 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKDAANLLNDALAIrektl 289
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL--------DPDDAEALYNLGLAYLRLGRYEEALADYEQALEL----- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 290 grdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkdhPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIy 369
Cdd:COG0457   72 ---DPDDAEALNNLGLALQALGRYEEALEDYDKALELD--------PDDAEALYNLGLALLELGRYDEAIEAYERALEL- 139

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 575403062 370 qtklgpdDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREE 435
Cdd:COG0457  140 -------DPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLA 198
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 35-149 1.61e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.66  E-value: 1.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062    35 LEALKNEHNSILQSLLET-LKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQ-VMMALSNHLNAVESEKQKLRAQVRR 112
Cdd:TIGR02168  234 LEELREELEELQEELKEAeEELEELTAELQELEEKLEELRLEVSELEEEIEELQkELYALANEISRLEQQKQILRERLAN 313

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 575403062   113 LCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLE 149
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELK 350
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
210-435 1.20e-27

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 111.64  E-value: 1.20e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 210 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKDAANLLNDALAIrektl 289
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL--------DPDDAEALYNLGLAYLRLGRYEEALADYEQALEL----- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 290 grdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkdhPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIy 369
Cdd:COG0457   72 ---DPDDAEALNNLGLALQALGRYEEALEDYDKALELD--------PDDAEALYNLGLALLELGRYDEAIEAYERALEL- 139

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 575403062 370 qtklgpdDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREE 435
Cdd:COG0457  140 -------DPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLA 198
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 212-417 1.14e-20

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 96.14  E-value: 1.14e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 212 RLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD--HPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTL 289
Cdd:NF040586 433 TLRLRFHLANALRSLGRYEEARELDEDTLERQRRVLGLGedHPHTLMTAGGLGADLRALGRFREALELDEETLERHRRVF 512

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 290 GRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIY 369
Cdd:NF040586 513 GEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLLSANNLARDLRELGRYAEALDLLEEALERY 592

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 575403062 370 QTKL-GPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRaHEREFG 417
Cdd:NF040586 593 REVLgGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYER-YRRRFG 640
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 226-421 3.17e-20

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 94.99  E-value: 3.17e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 226 QGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAI--REKTLGRDHPAVAATLNNL 303
Cdd:NF040586 405 RGDYESARDLAERALERWRERLGPDDRQTLRLRFHLANALRSLGRYEEARELDEDTLERqrRVLGLGEDHPHTLMTAGGL 484

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 304 AVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIYQTKLGPDDPNVAKT 383
Cdd:NF040586 485 GADLRALGRFREALELDEETLERHRRVFGEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLLS 564

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 575403062 384 KNNLASCYLKQGKFKQAETLYKEILTRaHEREFGSVDD 421
Cdd:NF040586 565 ANNLARDLRELGRYAEALDLLEEALER-YREVLGGPDH 601
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 227-417 7.96e-19

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 90.36  E-value: 7.96e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 227 GRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVL 306
Cdd:NF040586 492 GRFREALELDEETLERHRRVFGEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLLSANNLARD 571

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 307 YGKRGKYKEAEPLCKRALEIREKVL-GKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIYQTKLGPDDPNVAKTKN 385
Cdd:NF040586 572 LRELGRYAEALDLLEEALERYREVLgGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRRRFGPDHPDTLAAAL 651

                        170       180       190
                 ....*....|....*....|....*....|..
gi 575403062 386 NLASCYLKQGKFKQAETLYKEILTRaHEREFG 417
Cdd:NF040586 652 SLANDLRALGDADEARELAREVLDR-YRRVLG 682
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 205-414 2.49e-18

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 88.82  E-value: 2.49e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 205 GGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKT-SGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALA 283
Cdd:NF040586 554 LGPDHPRTLLSANNLARDLRELGRYAEALDLLEEALERYREVlGGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYE 633

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 284 IREKTLGRDHP-AVAATLNnLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYY 362
Cdd:NF040586 634 RYRRRFGPDHPdTLAAALS-LANDLRALGDADEARELAREVLDRYRRVLGEDHPFTLACRNNLAVLLRALGDPEEARELA 712

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 575403062 363 QRALGIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQA--ETLYKEILTRAHER 414
Cdd:NF040586 713 EAALEGLRERLGPDHPYTLAAAVNLANDLAALGDLDAAlgEEALERLRRLLGED 766
TPR_12 pfam13424
Tetratricopeptide repeat;
296-370 5.26e-18

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 78.58  E-value: 5.26e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 575403062  296 VAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIYQ 370
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAE 76
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 205-380 1.22e-16

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 83.43  E-value: 1.22e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 205 GGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD-VATMLNiLALVYRDQNKYKDAANLLNDALA 283
Cdd:NF040586 597 GGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRRRFGPDHPDtLAAALS-LANDLRALGDADEARELAREVLD 675

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 284 IREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALE-------------------------------------- 325
Cdd:NF040586 676 RYRRVLGEDHPFTLACRNNLAVLLRALGDPEEARELAEAALEglrerlgpdhpytlaaavnlandlaalgdldaalgeea 755

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 575403062 326 --------IREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIYQTKLGPDDPNV 380
Cdd:NF040586 756 lerlrrllGEDLRAGPDHPDTLACAANLALDLRATGRTEEAEELRADTLARLRRVLGPDHPDT 818
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 211-405 3.30e-10

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 60.43  E-value: 3.30e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062  211 ARLRTlhNLVIQYASQGRYEvavplckQALEDLEKTSGHDhPDVATMLNILALVYRDQNKYKDAANLLNDALAIrektlg 290
Cdd:TIGR02521  31 AKIRV--QLALGYLEQGDLE-------VAKENLDKALEHD-PDDYLAYLALALYYQQLGELEKAEDSFRRALTL------ 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062  291 rdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEirekvlGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIyq 370
Cdd:TIGR02521  95 --NPNNGDVLNNYGTFLCQQGKYEQAMQQFEQAIE------DPLYPQPARSLENAGLCALKAGDFDKAEKYLTRALQI-- 164

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 575403062  371 tklgpdDPNVAKTKNNLASCYLKQGKFKQAETLYK 405
Cdd:TIGR02521 165 ------DPQRPESLLELAELYYLRGQYKDARAYLE 193
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 306-420 1.29e-06

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 51.46  E-value: 1.29e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 306 LYgKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEV---------------------EY---- 360
Cdd:NF040586 402 LY-LRGDYESARDLAERALERWRERLGPDDRQTLRLRFHLANALRSLGRYEEAreldedtlerqrrvlglgedhPHtlmt 480

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 575403062 361 ------------YYQRAL-------GIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRaHEREFGSVD 420
Cdd:NF040586 481 agglgadlralgRFREALeldeetlERHRRVFGEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRR-RRRVLGPDH 558
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 218-298 1.31e-04

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 44.91  E-value: 1.31e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 218 NLVIQYASQGRYEVAvpLCKQALEDLE------KTSGHDHPDV-ATMLNiLALVYRDQNKYKDAANLLNDALAIREKTLG 290
Cdd:NF040586 736 NLANDLAALGDLDAA--LGEEALERLRrllgedLRAGPDHPDTlACAAN-LALDLRATGRTEEAEELRADTLARLRRVLG 812


                 ....*...
gi 575403062 291 RDHPAVAA 298
Cdd:NF040586 813 PDHPDTVA 820
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 35-149 1.61e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.66  E-value: 1.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062    35 LEALKNEHNSILQSLLET-LKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQ-VMMALSNHLNAVESEKQKLRAQVRR 112
Cdd:TIGR02168  234 LEELREELEELQEELKEAeEELEELTAELQELEEKLEELRLEVSELEEEIEELQkELYALANEISRLEQQKQILRERLAN 313

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 575403062   113 LCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLE 149
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELK 350
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 297-329 7.39e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.04  E-value: 7.39e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 575403062   297 AATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 329
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 29-161 1.05e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 41.54  E-value: 1.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062    29 KQVIQGLEALKNEHNSILQSLLETLkclkkDDESNLVEEKSSMIRKSLEMLElglSEAQVMMALSNHLNAV-ESEKQKLR 107
Cdd:smart00787 139 MKLLEGLKEGLDENLEGLKEDYKLL-----MKELELLNSIKPKLRDRKDALE---EELRQLKQLEDELEDCdPTELDRAK 210

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 575403062   108 AQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKkhLEFMNQLKKYDDDI 161
Cdd:smart00787 211 EKLKKLLQEIMIKVKKLEELEEELQELESKIEDLTNKK--SELNTEIAEAEKKL 262
Macoilin pfam09726
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ...
 62-147 6.60e-03

Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.


Pssm-ID: 462859 [Multi-domain]  Cd Length: 670  Bit Score: 39.45  E-value: 6.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062   62 SNLVEEKSSMIR--KSLEMLELGLSEA-QVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSV 138
Cdd:pfam09726 388 NNQLSKPDALVRleQDIKKLKAELQASrQTEQELRSQISSLTSLERSLKSELGQLRQENDLLQTKLHNAVSAKQKDKQTV 467

                          90
                  ....*....|...
gi 575403062  139 AQLE----EEKKH 147
Cdd:pfam09726 468 QQLEkrlkAEQEA 480
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
210-435 1.20e-27

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 111.64  E-value: 1.20e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 210 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKDAANLLNDALAIrektl 289
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL--------DPDDAEALYNLGLAYLRLGRYEEALADYEQALEL----- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 290 grdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkdhPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIy 369
Cdd:COG0457   72 ---DPDDAEALNNLGLALQALGRYEEALEDYDKALELD--------PDDAEALYNLGLALLELGRYDEAIEAYERALEL- 139

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 575403062 370 qtklgpdDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREE 435
Cdd:COG0457  140 -------DPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLA 198
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 212-417 1.14e-20

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 96.14  E-value: 1.14e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 212 RLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD--HPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTL 289
Cdd:NF040586 433 TLRLRFHLANALRSLGRYEEARELDEDTLERQRRVLGLGedHPHTLMTAGGLGADLRALGRFREALELDEETLERHRRVF 512

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 290 GRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIY 369
Cdd:NF040586 513 GEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLLSANNLARDLRELGRYAEALDLLEEALERY 592

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 575403062 370 QTKL-GPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRaHEREFG 417
Cdd:NF040586 593 REVLgGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYER-YRRRFG 640
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 226-421 3.17e-20

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 94.99  E-value: 3.17e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 226 QGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAI--REKTLGRDHPAVAATLNNL 303
Cdd:NF040586 405 RGDYESARDLAERALERWRERLGPDDRQTLRLRFHLANALRSLGRYEEARELDEDTLERqrRVLGLGEDHPHTLMTAGGL 484

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 304 AVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIYQTKLGPDDPNVAKT 383
Cdd:NF040586 485 GADLRALGRFREALELDEETLERHRRVFGEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLLS 564

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 575403062 384 KNNLASCYLKQGKFKQAETLYKEILTRaHEREFGSVDD 421
Cdd:NF040586 565 ANNLARDLRELGRYAEALDLLEEALER-YREVLGGPDH 601
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 208-411 1.22e-19

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 92.75  E-value: 1.22e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 208 EIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKtsGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIrek 287
Cdd:COG3914   33 EAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAA--AAALLLLAALLELAALLLQALGRYEEALALYRRALAL--- 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 288 tlgrdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkdHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALG 367
Cdd:COG3914  108 -----NPDNAEALFNLGNLLLALGRLEEALAALRRALAL--------NPDFAEAYLNLGEALRRLGRLEEAIAALRRALE 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 575403062 368 IyqtklgpdDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRA 411
Cdd:COG3914  175 L--------DPDNAEALNNLGNALQDLGRLEEAIAAYRRALELD 210
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 227-417 7.96e-19

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 90.36  E-value: 7.96e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 227 GRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVL 306
Cdd:NF040586 492 GRFREALELDEETLERHRRVFGEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLLSANNLARD 571

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 307 YGKRGKYKEAEPLCKRALEIREKVL-GKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIYQTKLGPDDPNVAKTKN 385
Cdd:NF040586 572 LRELGRYAEALDLLEEALERYREVLgGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRRRFGPDHPDTLAAAL 651

                        170       180       190
                 ....*....|....*....|....*....|..
gi 575403062 386 NLASCYLKQGKFKQAETLYKEILTRaHEREFG 417
Cdd:NF040586 652 SLANDLRALGDADEARELAREVLDR-YRRVLG 682
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 205-414 2.49e-18

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 88.82  E-value: 2.49e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 205 GGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKT-SGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALA 283
Cdd:NF040586 554 LGPDHPRTLLSANNLARDLRELGRYAEALDLLEEALERYREVlGGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYE 633

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 284 IREKTLGRDHP-AVAATLNnLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYY 362
Cdd:NF040586 634 RYRRRFGPDHPdTLAAALS-LANDLRALGDADEARELAREVLDRYRRVLGEDHPFTLACRNNLAVLLRALGDPEEARELA 712

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 575403062 363 QRALGIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQA--ETLYKEILTRAHER 414
Cdd:NF040586 713 EAALEGLRERLGPDHPYTLAAAVNLANDLAALGDLDAAlgEEALERLRRLLGED 766
TPR_12 pfam13424
Tetratricopeptide repeat;
296-370 5.26e-18

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 78.58  E-value: 5.26e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 575403062  296 VAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIYQ 370
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAE 76
TPR_12 pfam13424
Tetratricopeptide repeat;
253-329 5.05e-17

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 75.89  E-value: 5.05e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 575403062  253 DVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 329
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 205-380 1.22e-16

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 83.43  E-value: 1.22e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 205 GGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD-VATMLNiLALVYRDQNKYKDAANLLNDALA 283
Cdd:NF040586 597 GGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRRRFGPDHPDtLAAALS-LANDLRALGDADEARELAREVLD 675

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 284 IREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALE-------------------------------------- 325
Cdd:NF040586 676 RYRRVLGEDHPFTLACRNNLAVLLRALGDPEEARELAEAALEglrerlgpdhpytlaaavnlandlaalgdldaalgeea 755

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 575403062 326 --------IREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIYQTKLGPDDPNV 380
Cdd:NF040586 756 lerlrrllGEDLRAGPDHPDTLACAANLALDLRATGRTEEAEELRADTLARLRRVLGPDHPDT 818
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 210-413 2.01e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 76.69  E-value: 2.01e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 210 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEdlektsghDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIrektl 289
Cdd:COG2956   73 PDRAEALLELAQDYLKAGLLDRAEELLEKLLE--------LDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKL----- 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 290 grdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkdHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIy 369
Cdd:COG2956  140 ---GPENAHAYCELAELYLEQGDYDEAIEALEKALKL--------DPDCARALLLLAELYLEQGDYEEAIAALERALEQ- 207

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 575403062 370 qtklgpdDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHE 413
Cdd:COG2956  208 -------DPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS 244
TPR_12 pfam13424
Tetratricopeptide repeat;
212-287 1.16e-14

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 68.95  E-value: 1.16e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 575403062  212 RLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREK 287
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 223-413 2.64e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 73.22  E-value: 2.64e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 223 YASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTlgrdhpavAATLNN 302
Cdd:COG2956   52 YRRRGEYDRAIRIHQKLLER--------DPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDD--------AEALRL 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 303 LAVLYGKRGKYKEAEPLCKRALEIrekvlgkdHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIyqtklgpdDPNVAK 382
Cdd:COG2956  116 LAEIYEQEGDWEKAIEVLERLLKL--------GPENAHAYCELAELYLEQGDYDEAIEALEKALKL--------DPDCAR 179

                        170       180       190
                 ....*....|....*....|....*....|.
gi 575403062 383 TKNNLASCYLKQGKFKQAETLYKEILTRAHE 413
Cdd:COG2956  180 ALLLLAELYLEQGDYEEAIAALERALEQDPD 210
TPR_10 pfam13374
Tetratricopeptide repeat;
296-337 3.75e-14

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 66.37  E-value: 3.75e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 575403062  296 VAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPD 337
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHPD 42
TPR_12 pfam13424
Tetratricopeptide repeat;
337-411 1.01e-13

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 66.26  E-value: 1.01e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 575403062  337 DVAKQLNNLALLCQNQGKYEEVEYYYQRALGIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRA 411
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALA 75
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 261-413 2.92e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 67.14  E-value: 2.92e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 261 LALVYRDQNKYKDAANLLNDALAIrektlgrdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkdHPDVAK 340
Cdd:COG4783   10 LAQALLLAGDYDEAEALLEKALEL--------DPDNPEAFALLGEILLQLGDLDEAIVLLHEALEL--------DPDEPE 73

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 575403062 341 QLNNLALLCQNQGKYEEVEYYYQRALgiyqtKLGPDDPNVAktkNNLASCYLKQGKFKQAETLYKEILTRAHE 413
Cdd:COG4783   74 ARLNLGLALLKAGDYDEALALLEKAL-----KLDPEHPEAY---LRLARAYRALGRPDEAIAALEKALELDPD 138
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 211-369 4.42e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 66.75  E-value: 4.42e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 211 ARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKDAANLLNDALAIrektlg 290
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALEL--------DPDNPEAFALLGEILLQLGDLDEAIVLLHEALEL------ 67

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 575403062 291 rdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEirekvLGKDHPDVakqLNNLALLCQNQGKYEEVEYYYQRALGIY 369
Cdd:COG4783   68 --DPDEPEARLNLGLALLKAGDYDEALALLEKALK-----LDPEHPEA---YLRLARAYRALGRPDEAIAALEKALELD 136
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 222-414 1.11e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 70.79  E-value: 1.11e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 222 QYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKY-KDAANLLNDALAIREKTLGRDHPAVAATL 300
Cdd:COG3914    2 AAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALaEAAAAALLALAAGEAAAAAAALLLLAALL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 301 NNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkdHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALgiyqtKLGPDDPNV 380
Cdd:COG3914   82 ELAALLLQALGRYEEALALYRRALAL--------NPDNAEALFNLGNLLLALGRLEEALAALRRAL-----ALNPDFAEA 148

                        170       180       190
                 ....*....|....*....|....*....|....
gi 575403062 381 AktkNNLASCYLKQGKFKQAETLYKEILTRAHER 414
Cdd:COG3914  149 Y---LNLGEALRRLGRLEEAIAALRRALELDPDN 179
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 249-411 5.62e-12

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 63.83  E-value: 5.62e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 249 HDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIre 328
Cdd:COG5010    6 GFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQL-- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 329 kvlgkdHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALgiyqtKLGPDDPNVAktkNNLASCYLKQGKFKQAETLYKEIL 408
Cdd:COG5010   84 ------DPNNPELYYNLALLYSRSGDKDEAKEYYEKAL-----ALSPDNPNAY---SNLAALLLSLGQDDEAKAALQRAL 149


                 ...
gi 575403062 409 TRA 411
Cdd:COG5010  150 GTS 152
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
218-405 1.01e-11

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 64.94  E-value: 1.01e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 218 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIRektlgrdhPAVA 297
Cdd:COG4785   36 ALAIALADLALALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELD--------PDLA 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 298 ATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkdhPDVAKQLNNLALLCQNQGKYEEVEYYYQRALgiyqtKLGPDD 377
Cdd:COG4785  108 EAYNNRGLAYLLLGDYDAALEDFDRALELD--------PDYAYAYLNRGIALYYLGRYELAIADLEKAL-----ELDPND 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 575403062 378 P-------------NVAKTKNNL----ASCYLKQGKFKQAETLYK 405
Cdd:COG4785  175 PeralwlylaerklDPEKALALLledwATAYLLQGDTEEARELFK 219
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
306-408 6.64e-11

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 59.03  E-value: 6.64e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 306 LYGKRGKYKEAEPLCKRALEIrekvlgkdHPDVAKQLNNLALLCQNQGKYEEVEYYyQRALGIyqtklgpdDPNVAKTKN 385
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALEL--------DPDNADALNNLGLLLLEQGRYDEAIAL-EKALKL--------DPNNAEALL 63

                         90       100
                 ....*....|....*....|...
gi 575403062 386 NLASCYLKQGKFKQAETLYKEIL 408
Cdd:COG3063   64 NLAELLLELGDYDEALAYLERAL 86
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
210-370 7.47e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 62.72  E-value: 7.47e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 210 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKDAANLLNDALAIRektl 289
Cdd:COG0457   73 PDDAEALNNLGLALQALGRYEEALEDYDKALEL--------DPDDAEALYNLGLALLELGRYDEAIEAYERALELD---- 140

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 290 grdhPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIY 369
Cdd:COG0457  141 ----PDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTL 216


                 .
gi 575403062 370 Q 370
Cdd:COG0457  217 A 217
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 260-415 1.14e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 62.44  E-value: 1.14e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 260 ILALVYRDQNKYKDAANLLNDALAIrektlgrdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkdHPDVA 339
Cdd:COG2956   13 FKGLNYLLNGQPDKAIDLLEEALEL--------DPETVEAHLALGNLYRRRGEYDRAIRIHQKLLER--------DPDRA 76

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 575403062 340 KQLNNLALLCQNQGKYEEVEYYYQRALGIyqtklgpdDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRAHERE 415
Cdd:COG2956   77 EALLELAQDYLKAGLLDRAEELLEKLLEL--------DPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENA 144
TPR_10 pfam13374
Tetratricopeptide repeat;
254-294 1.93e-10

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 55.97  E-value: 1.93e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 575403062  254 VATMLNILALVYRDQNKYKDAANLLNDALAIREKTLGRDHP 294
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHP 41
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 295-411 2.86e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 58.66  E-value: 2.86e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 295 AVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkdHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALgiyqtKLG 374
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALEL--------DPDNPEAFALLGEILLQLGDLDEAIVLLHEAL-----ELD 68

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 575403062 375 PDDPNVAktkNNLASCYLKQGKFKQAETLYKEILTRA 411
Cdd:COG4783   69 PDEPEAR---LNLGLALLKAGDYDEALALLEKALKLD 102
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
264-366 2.92e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 57.10  E-value: 2.92e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 264 VYRDQNKYKDAANLLNDALAIrektlgrdHPAVAATLNNLAVLYGKRGKYKEAEPLcKRALEIrekvlgkdHPDVAKQLN 343
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALEL--------DPDNADALNNLGLLLLEQGRYDEAIAL-EKALKL--------DPNNAEALL 63

                         90       100
                 ....*....|....*....|...
gi 575403062 344 NLALLCQNQGKYEEVEYYYQRAL 366
Cdd:COG3063   64 NLAELLLELGDYDEALAYLERAL 86
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 211-405 3.30e-10

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 60.43  E-value: 3.30e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062  211 ARLRTlhNLVIQYASQGRYEvavplckQALEDLEKTSGHDhPDVATMLNILALVYRDQNKYKDAANLLNDALAIrektlg 290
Cdd:TIGR02521  31 AKIRV--QLALGYLEQGDLE-------VAKENLDKALEHD-PDDYLAYLALALYYQQLGELEKAEDSFRRALTL------ 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062  291 rdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEirekvlGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIyq 370
Cdd:TIGR02521  95 --NPNNGDVLNNYGTFLCQQGKYEQAMQQFEQAIE------DPLYPQPARSLENAGLCALKAGDFDKAEKYLTRALQI-- 164

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 575403062  371 tklgpdDPNVAKTKNNLASCYLKQGKFKQAETLYK 405
Cdd:TIGR02521 165 ------DPQRPESLLELAELYYLRGQYKDARAYLE 193
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 210-368 4.46e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 58.43  E-value: 4.46e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 210 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIrektl 289
Cdd:COG5010    9 RLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQL----- 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 575403062 290 grdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkdHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGI 368
Cdd:COG5010   84 ---DPNNPELYYNLALLYSRSGDKDEAKEYYEKALAL--------SPDNPNAYSNLAALLLSLGQDDEAKAALQRALGT 151
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 238-388 9.01e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 56.94  E-value: 9.01e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 238 QALEDLEKTSGHDHPDVATMLNiLALVYRDQNKYKDAANLLNDALAIRektlgrdhPAVAATLNNLAVLYGKRGKYKEAE 317
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLL-LGRAYLRLGRYDEALAAYEKALRLD--------PDNADALLDLAEALLAAGDTEEAE 71

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 575403062 318 PLCKRALEIrekvlgkdHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALgiyqtKLGPDDPNVAKTKNNLA 388
Cdd:COG4235   72 ELLERALAL--------DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLL-----ALLPADAPARLLEASIA 129
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
223-331 2.75e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 54.41  E-value: 2.75e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 223 YASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKDAANLlNDALAIrektlgrdHPAVAATLNN 302
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALEL--------DPDNADALNNLGLLLLEQGRYDEAIAL-EKALKL--------DPNNAEALLN 64

                         90       100
                 ....*....|....*....|....*....
gi 575403062 303 LAVLYGKRGKYKEAEPLCKRALEIREKVL 331
Cdd:COG3063   65 LAELLLELGDYDEALAYLERALELDPSAL 93
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 261-480 1.08e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.08  E-value: 1.08e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 261 LALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKdHPDVAK 340
Cdd:COG3914    1 AAAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAA-LLLLAA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 341 QLNNLALLCQNQGKYEEVEYYYQRALGIyqtklgpdDPNVAKTKNNLASCYLKQGKFKQAETLYKEILtraherefgSVD 420
Cdd:COG3914   80 LLELAALLLQALGRYEEALALYRRALAL--------NPDNAEALFNLGNLLLALGRLEEALAALRRAL---------ALN 142

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 575403062 421 DENKPIWM---HAEEREeckGKQKDGSAFgeyggWYKACKVDsPTVTTTLKNLGALYRRQGKF 480
Cdd:COG3914  143 PDFAEAYLnlgEALRRL---GRLEEAIAA-----LRRALELD-PDNAEALNNLGNALQDLGRL 196
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 291-411 1.38e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 53.47  E-value: 1.38e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 291 RDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkdhPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIyq 370
Cdd:COG4235   11 AANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLD--------PDNADALLDLAEALLAAGDTEEAEELLERALAL-- 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 575403062 371 tklgpdDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRA 411
Cdd:COG4235   81 ------DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALL 115
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 210-366 4.55e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 54.74  E-value: 4.55e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 210 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEdlektsghDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIrektl 289
Cdd:COG2956  141 PENAHAYCELAELYLEQGDYDEAIEALEKALK--------LDPDCARALLLLAELYLEQGDYEEAIAALERALEQ----- 207

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 575403062 290 grdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkdHPDVAkQLNNLALLCQNQGKYEEVEYYYQRAL 366
Cdd:COG2956  208 ---DPDYLPALPRLAELYEKLGDPEEALELLRKALEL--------DPSDD-LLLALADLLERKEGLEAALALLERQL 272
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
261-434 2.06e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 51.84  E-value: 2.06e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 261 LALVYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkdhPDVAK 340
Cdd:COG4785   37 LAIALADLALALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELD--------PDLAE 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 341 QLNNLALLCQNQGKYEEVEYYYQRALgiyqtKLGPDDPNVaktKNNLASCYLKQGKFKQAEtlykEILTRAHerEFGSVD 420
Cdd:COG4785  109 AYNNRGLAYLLLGDYDAALEDFDRAL-----ELDPDYAYA---YLNRGIALYYLGRYELAI----ADLEKAL--ELDPND 174

                        170
                 ....*....|....
gi 575403062 421 DENkPIWMHAEERE 434
Cdd:COG4785  175 PER-ALWLYLAERK 187
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 309-410 2.35e-07

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 49.22  E-value: 2.35e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 309 KRGKYKEAEPLCKRALEirekvLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIYqtklgPDDPNVAKTKNNLA 388
Cdd:COG1729    5 KAGDYDEAIAAFKAFLK-----RYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRY-----PDSPKAPDALLKLG 74

                         90       100
                 ....*....|....*....|..
gi 575403062 389 SCYLKQGKFKQAETLYKEILTR 410
Cdd:COG1729   75 LSYLELGDYDKARATLEELIKK 96
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 250-409 3.75e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 53.16  E-value: 3.75e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062  250 DHPDVATMLNILALVYRDQNKYKDAANLLNDALAIrektlgrdHPAVAATLNNLAVLYGKRgKYKEAEPLCKRALEIRek 329
Cdd:TIGR02917 765 THPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKK--------APDNAVVLNNLAWLYLEL-KDPRALEYAERALKLA-- 833

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062  330 vlgkdhPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIyqtklGPDDPNVaktKNNLASCYLKQGKFKQAETLYKEILT 409
Cdd:TIGR02917 834 ------PNIPAILDTLGWLLVEKGEADRALPLLRKAVNI-----APEAAAI---RYHLALALLATGRKAEARKELDKLLN 899
TPR_10 pfam13374
Tetratricopeptide repeat;
213-253 5.70e-07

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 45.96  E-value: 5.70e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 575403062  213 LRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD 253
Cdd:pfam13374   2 ASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHPD 42
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
210-366 7.01e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 50.30  E-value: 7.01e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 210 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKDAANLLNDALAIRektl 289
Cdd:COG4785   70 PDLAQLYYERGVAYDSLGDYDLAIADFDQALEL--------DPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELD---- 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 290 grdhPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREK----------VLGKDHPDVAKQL--NNLALLCQNQGKYEE 357
Cdd:COG4785  138 ----PDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNdperalwlylAERKLDPEKALALllEDWATAYLLQGDTEE 213


                 ....*....
gi 575403062 358 VEYYYQRAL 366
Cdd:COG4785  214 ARELFKLAL 222
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 306-420 1.29e-06

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 51.46  E-value: 1.29e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 306 LYgKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEV---------------------EY---- 360
Cdd:NF040586 402 LY-LRGDYESARDLAERALERWRERLGPDDRQTLRLRFHLANALRSLGRYEEAreldedtlerqrrvlglgedhPHtlmt 480

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 575403062 361 ------------YYQRAL-------GIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEILTRaHEREFGSVD 420
Cdd:NF040586 481 agglgadlralgRFREALeldeetlERHRRVFGEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRR-RRRVLGPDH 558
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 237-411 1.85e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.85  E-value: 1.85e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062  237 KQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTLgrdhPAVAAtlnnLAVLYGKRGKYKEA 316
Cdd:TIGR02917 107 QQVLDELPGKTLLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSL----YAKLG----LAQLALAENRFDEA 178

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062  317 EPLCKRALEIrekvlgkdHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALgiyqtKLGPDDPNVaktKNNLASCYLKQGK 396
Cdd:TIGR02917 179 RALIDEVLTA--------DPGNVDALLLKGDLLLSLGNIELALAAYRKAI-----ALRPNNIAV---LLALATILIEAGE 242

                         170
                  ....*....|....*
gi 575403062  397 FKQAETLYKEILTRA 411
Cdd:TIGR02917 243 FEEAEKHADALLKKA 257
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 210-326 2.48e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.11  E-value: 2.48e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 210 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEdlektsghDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREktl 289
Cdd:COG4783   35 PDNPEAFALLGEILLQLGDLDEAIVLLHEALE--------LDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDP--- 103

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 575403062 290 grDHPAVaatLNNLAVLYGKRGKYKEAEPLCKRALEI 326
Cdd:COG4783  104 --EHPEA---YLRLARAYRALGRPDEAIAALEKALEL 135
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 261-326 3.34e-06

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 44.63  E-value: 3.34e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 575403062  261 LALVYRDQNKYKDAANLLNDALAirektLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEI 326
Cdd:pfam13432   3 LARAALRAGDYDDAAAALEAALA-----RFPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRA 63
TPR_10 pfam13374
Tetratricopeptide repeat;
338-379 3.82e-06

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 43.64  E-value: 3.82e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 575403062  338 VAKQLNNLALLCQNQGKYEEVEYYYQRALGIYQTKLGPDDPN 379
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHPD 42
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 210-326 4.46e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.15  E-value: 4.46e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 210 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEdLEktsghdhPDVATMLNILALVYRDQNKYKDAANLLNDALAIrektl 289
Cdd:COG4235   14 PNDAEGWLLLGRAYLRLGRYDEALAAYEKALR-LD-------PDNADALLDLAEALLAAGDTEEAEELLERALAL----- 80

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 575403062 290 grdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEI 326
Cdd:COG4235   81 ---DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLAL 114
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 210-428 2.01e-05

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 46.92  E-value: 2.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062  210 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKtsgHDHPDVATM-LNILALVYRDQNKYKDAANLLNDALAIREKT 288
Cdd:pfam17874  37 LARGLATFVLGEAYLCLGDLDAALQAMREAEALARR---ADSPHVTLWaLLQQGEILRAQGRLHQALETYQQALQLARDH 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062  289 LGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVlgkdHPDVAKQLN-NLALLCQNQGKYEEVEYYYQRALG 367
Cdd:pfam17874 114 GLQHLPLHGFLLVGLADLLYEWNDLEEAEQHAQQGIQLGRQW----EPDAAVDAYvLLARIALAQGELEEALTLLRRAEL 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062  368 IYQTK----------------------------------LGPDDPN---VAKTKNNLASCYLKQGKFKQAETLYKEILTR 410
Cdd:pfam17874 190 LARQSffhvdwlanaervrvrlwlargdlraavrwlraaEPPSDADnhfLERELRNLARVLLALGRFDDALSLLERLQNL 269

                         250
                  ....*....|....*...
gi 575403062  411 AheREFGSVDDENKpIWM 428
Cdd:pfam17874 270 A--EQLGRVRSLIE-NLI 284
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 321-413 2.29e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 44.23  E-value: 2.29e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 321 KRALEIREKVlgKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALgiyqtKLGPDDPNVaktKNNLASCYLKQGKFKQA 400
Cdd:COG4235    1 EAIARLRQAL--AANPNDAEGWLLLGRAYLRLGRYDEALAAYEKAL-----RLDPDNADA---LLDLAEALLAAGDTEEA 70

                         90
                 ....*....|...
gi 575403062 401 ETLYKEILTRAHE 413
Cdd:COG4235   71 EELLERALALDPD 83
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 265-389 9.19e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 41.90  E-value: 9.19e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 265 YRDQNKYKDAANLLNDALAirektLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEirekvLGKDHPDVAKQLNN 344
Cdd:COG1729    3 LLKAGDYDEAIAAFKAFLK-----RYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLK-----RYPDSPKAPDALLK 72

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 575403062 345 LALLCQNQGKYEEVEYYYQRALGIYqtklgPDDPNVAKTKNNLAS 389
Cdd:COG1729   73 LGLSYLELGDYDKARATLEELIKKY-----PDSEAAKEARARLAR 112
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 218-298 1.31e-04

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 44.91  E-value: 1.31e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 218 NLVIQYASQGRYEVAvpLCKQALEDLE------KTSGHDHPDV-ATMLNiLALVYRDQNKYKDAANLLNDALAIREKTLG 290
Cdd:NF040586 736 NLANDLAALGDLDAA--LGEEALERLRrllgedLRAGPDHPDTlACAAN-LALDLRATGRTEEAEELRADTLARLRRVLG 812


                 ....*...
gi 575403062 291 RDHPAVAA 298
Cdd:NF040586 813 PDHPDTVA 820
TPR_1 pfam00515
Tetratricopeptide repeat;
297-329 1.44e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.94  E-value: 1.44e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 575403062  297 AATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 329
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 35-149 1.61e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.66  E-value: 1.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062    35 LEALKNEHNSILQSLLET-LKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQ-VMMALSNHLNAVESEKQKLRAQVRR 112
Cdd:TIGR02168  234 LEELREELEELQEELKEAeEELEELTAELQELEEKLEELRLEVSELEEEIEELQkELYALANEISRLEQQKQILRERLAN 313

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 575403062   113 LCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLE 149
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELK 350
TPR_7 pfam13176
Tetratricopeptide repeat;
299-334 2.37e-04

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 38.68  E-value: 2.37e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 575403062  299 TLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKD 334
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYDRE 36
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 302-378 4.71e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 38.86  E-value: 4.71e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 575403062  302 NLAVLYGKRGKYKEAEPLCKRALEirekvLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIYqtklgPDDP 378
Cdd:pfam13432   2 ALARAALRAGDYDDAAAALEAALA-----RFPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAA-----PGDP 68
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 223-284 5.51e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 38.47  E-value: 5.51e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 575403062  223 YASQGRYEVAVPLCKQALEdlektSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDALAI 284
Cdd:pfam13432   7 ALRAGDYDDAAAALEAALA-----RFPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRA 63
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 297-329 7.39e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.04  E-value: 7.39e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 575403062   297 AATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 329
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 29-161 1.05e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 41.54  E-value: 1.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062    29 KQVIQGLEALKNEHNSILQSLLETLkclkkDDESNLVEEKSSMIRKSLEMLElglSEAQVMMALSNHLNAV-ESEKQKLR 107
Cdd:smart00787 139 MKLLEGLKEGLDENLEGLKEDYKLL-----MKELELLNSIKPKLRDRKDALE---EELRQLKQLEDELEDCdPTELDRAK 210

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 575403062   108 AQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKkhLEFMNQLKKYDDDI 161
Cdd:smart00787 211 EKLKKLLQEIMIKVKKLEELEEELQELESKIEDLTNKK--SELNTEIAEAEKKL 262
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
210-289 1.38e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.23  E-value: 1.38e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062 210 PARLRTLHNLVIQYASQGRYEVAVPLcKQALEdlektsghDHPDVATMLNILALVYRDQNKYKDAANLLNDALAIREKTL 289
Cdd:COG3063   23 PDNADALNNLGLLLLEQGRYDEAIAL-EKALK--------LDPNNAEALLNLAELLLELGDYDEALAYLERALELDPSAL 93
TPR_1 pfam00515
Tetratricopeptide repeat;
339-366 3.49e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.09  E-value: 3.49e-03
                          10        20
                  ....*....|....*....|....*...
gi 575403062  339 AKQLNNLALLCQNQGKYEEVEYYYQRAL 366
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKAL 28
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 10-149 4.13e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 40.05  E-value: 4.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062    10 YIKEEKLEKLT-QDEIISKTKQVIQGLEALKNEHNSILQSLLETlKCLKKDDESNLVEEKSSMIRKSLEMLELGLSEAQV 88
Cdd:TIGR02169  748 SLEQEIENVKSeLKELEARIEELEEDLHKLEEALNDLEARLSHS-RIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTL 826

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 575403062    89 MMA-LSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSVAQLEEEKKHLE 149
Cdd:TIGR02169  827 EKEyLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLK 888
TPR_10 pfam13374
Tetratricopeptide repeat;
380-417 5.16e-03

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 34.79  E-value: 5.16e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 575403062  380 VAKTKNNLASCYLKQGKFKQAETLYKEILTRaHEREFG 417
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALAI-RERVLG 37
Macoilin pfam09726
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ...
 62-147 6.60e-03

Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.


Pssm-ID: 462859 [Multi-domain]  Cd Length: 670  Bit Score: 39.45  E-value: 6.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 575403062   62 SNLVEEKSSMIR--KSLEMLELGLSEA-QVMMALSNHLNAVESEKQKLRAQVRRLCQENQWLRDELANTQQKLQKSEQSV 138
Cdd:pfam09726 388 NNQLSKPDALVRleQDIKKLKAELQASrQTEQELRSQISSLTSLERSLKSELGQLRQENDLLQTKLHNAVSAKQKDKQTV 467

                          90
                  ....*....|...
gi 575403062  139 AQLE----EEKKH 147
Cdd:pfam09726 468 QQLEkrlkAEQEA 480
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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