|
Name |
Accession |
Description |
Interval |
E-value |
| CEP209_CC5 |
pfam16574 |
Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry ... |
1289-1416 |
8.43e-44 |
|
Coiled-coil region of centrosome protein CE290; CEP290 and similar centrosomal proteins carry a number of coiled-coil regions, and this is the fifth along the length of the protein. It is thought that the proteins are involved in cilia biosynthesis.
Pssm-ID: 465184 [Multi-domain] Cd Length: 128 Bit Score: 156.01 E-value: 8.43e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1289 TMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDTKGAQKVINWHMKIEELRLQELKLNRELVKD 1368
Cdd:pfam16574 1 TMIQLQEDKAKLQEELKHAEEERRRAEDRAQELELKLKGLEELISTLKDGKGAQKVTEWHKKMEEIRLQELKLQRELSKQ 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 2462534488 1369 KEEIKYLNNIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLER 1416
Cdd:pfam16574 81 KEEIKYLENLIREQERTISSLEEEIVQQTKLHEERQLAWDQREVELER 128
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1082-1889 |
8.63e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 77.79 E-value: 8.63e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1082 HLRTSLKQMEERNFELETKFAELTKinldaqkvEQMLRDELADSVSKAVSDADRqriLELEKNEMELKVEV------SKL 1155
Cdd:TIGR02168 226 ELALLVLRLEELREELEELQEELKE--------AEEELEELTAELQELEEKLEE---LRLEVSELEEEIEElqkelyALA 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1156 REISDIaRRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKSLIAKlhqhnvSLQLSEATALGKLESITSKLQKMEAYN 1235
Cdd:TIGR02168 295 NEISRL-EQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA------ELEEKLEELKEELESLEAELEELEAEL 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1236 LRLEQKLDEKEQALYYARlegrNRAKHLRQTIQSLRRQFsgalplaQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNME 1315
Cdd:TIGR02168 368 EELESRLEELEEQLETLR----SKVAQLELQIASLNNEI-------ERLEARLERLEDRRERLQQEIEELLKKLEEAELK 436
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1316 NKTLEMELKLKGLEELISTLKDTkgAQKVINWHMKIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIVQ 1395
Cdd:TIGR02168 437 ELQAELEELEEELEELQEELERL--EEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKN 514
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1396 QNKFHEERQMAWDQREVDLERQLDIF----DRQQNEILNAAQKFEEATGSIPDPSLPLPNQLE---IALRKIKENIRIIL 1468
Cdd:TIGR02168 515 QSGLSGILGVLSELISVDEGYEAAIEaalgGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPldsIKGTEIQGNDREIL 594
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1469 ETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELR--LRLPATAEREKLIAELGRKEMEPKSHHTLKIAhQTIANMQ 1546
Cdd:TIGR02168 595 KNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDnaLELAKKLRPGYRIVTLDGDLVRPGGVITGGSA-KTNSSIL 673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1547 ARLNQKEEVLKKYQRLLEKAREEQREIVkkheedlhilhhRLELQADSSLNKFKQTAWDLMKQSPTPVPTNKHFIRLAEM 1626
Cdd:TIGR02168 674 ERRREIEELEEKIEELEEKIAELEKALA------------ELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAE 741
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1627 EQTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEfeniklqlqenHEDEVKKVKAEVEDLKYLLDQSQKESQCLKS 1706
Cdd:TIGR02168 742 VEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAE-----------AEAEIEELEAQIEQLKEELKALREALDELRA 810
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1707 ELQAQKEANSRAptttmRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDrhtre 1786
Cdd:TIGR02168 811 ELTLLNEEAANL-----RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLN----- 880
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1787 lktQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQG--K 1864
Cdd:TIGR02168 881 ---ERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEeaE 957
|
810 820
....*....|....*....|....*
gi 2462534488 1865 PLTDNKQSLIEELQRKVKKLENQLE 1889
Cdd:TIGR02168 958 ALENKIEDDEEEARRRLKRLENKIK 982
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1462-2338 |
4.01e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 75.48 E-value: 4.01e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1462 ENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPaTAEREKLIAELGRKEMEPKSHHTLKIAHQT 1541
Cdd:TIGR02168 155 EERRAIFEEAAGISKYKERRKETERKLERTRENLDRLEDILNELERQLK-SLERQAEKAERYKELKAELRELELALLVLR 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1542 IANMQARLNQKEEVLKKYQRLLEKAREEQREIVKKHEEdlhilhHRLELQADSSLNKFKQTAWDLMKQsptpvptnkhfi 1621
Cdd:TIGR02168 234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEE------LRLEVSELEEEIEELQKELYALAN------------ 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1622 RLAEMEQTVAEQDDSLSSLLVKLKKVS---QDLERQREITELKVKEFENIKLQLQENHE---DEVKKVKAEVEDLKYLLD 1695
Cdd:TIGR02168 296 EISRLEQQKQILRERLANLERQLEELEaqlEELESKLDELAEELAELEEKLEELKEELEsleAELEELEAELEELESRLE 375
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1696 QSQKESQCLKSEL-QAQKEANSraptttMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHL 1774
Cdd:TIGR02168 376 ELEEQLETLRSKVaQLELQIAS------LNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEL 449
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1775 -NVQQIVDRHTRELKTQVEDLNENLLKLKEAlKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQ 1853
Cdd:TIGR02168 450 eELQEELERLEEALEELREELEEAEQALDAA-ERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSEL 528
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1854 IK-----------RLTSGLQgKPLTDNKQSLIEElqrkVKKLENQLEGKVE--EVDLKPMKEKNAKEELIRweegkkwqA 1920
Cdd:TIGR02168 529 ISvdegyeaaieaALGGRLQ-AVVVENLNAAKKA----IAFLKQNELGRVTflPLDSIKGTEIQGNDREIL--------K 595
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1921 KIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADkekltlqrklkttgmTVDQVLGIRalesekELEELKKRNLDLENDI 2000
Cdd:TIGR02168 596 NIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVD---------------DLDNALELA------KKLRPGYRIVTLDGDL 654
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2001 LY----------MRAHQALPRDSVVEDLHLQNRYLQEKLHALEKQFskdtyskpsisgiesDDHCQREQELQKENLKLSS 2070
Cdd:TIGR02168 655 VRpggvitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKAL---------------AELRKELEELEEELEQLRK 719
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2071 ENIELKFQLEQANKDLPRLKNQVRDLKEMCEFLKKEKAEVQRKLGHVRgAELEKLKAHLgHQLSMHYESKTKGTEKIIAE 2150
Cdd:TIGR02168 720 ELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE-ERLEEAEEEL-AEAEAEIEELEAQIEQLKEE 797
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2151 NERLRKELKKETDAAEKLRIAKNNLEILNEKMTVQLEETGKRLQFAESRGPQLEGADSKSWKSIvvtRMYETKLKELETD 2230
Cdd:TIGR02168 798 LKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEI---EELEELIEELESE 874
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2231 IAKKNQSITDLKQLVKEATEREQKVNKYNEDLEQQIKILKHVPEGAETEQG-LKRELQVLRLANHQLDKEKAELiHQIEA 2309
Cdd:TIGR02168 875 LEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAqLELRLEGLEVRIDNLQERLSEE-YSLTL 953
|
890 900
....*....|....*....|....*....
gi 2462534488 2310 NKDQSGAESTIPDADQLKEKIKDLETQLK 2338
Cdd:TIGR02168 954 EEAEALENKIEDDEEEARRRLKRLENKIK 982
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
524-1275 |
1.90e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 66.62 E-value: 1.90e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 524 KHLKQQQYRAENQILLKEIESLEEERLDLKKKIRQMAQERgkRSATSGLTTEDLNLTENISQGDRISERKLD----LLSL 599
Cdd:TIGR02168 216 KELKAELRELELALLVLRLEELREELEELQEELKEAEEEL--EELTAELQELEEKLEELRLEVSELEEEIEElqkeLYAL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 600 KN-MSEAQSKNEFLSRELIEKERDLERSRTVIAKFQNKLKELVEENKQLEEGMKEILQAIKEMQKDpdvkggetsliIPS 678
Cdd:TIGR02168 294 ANeISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAE-----------LEE 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 679 LERLVNAIESKNAEgifdaslhLKAQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKETSLLRQSEGSNV 758
Cdd:TIGR02168 363 LEAELEELESRLEE--------LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 759 VFK---GIDLPDGIAPSSASIINSQNEYLIHLLQELENKEKKLKNLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKETWKt 835
Cdd:TIGR02168 435 LKElqaELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLK- 513
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 836 esktiKEEKRKLEDQVQQDAIKV-KEYNNLLNALqmdsdemkkiLAENSRKITVLQVNEKSLIRQYTTLVELER------ 908
Cdd:TIGR02168 514 -----NQSGLSGILGVLSELISVdEGYEAAIEAA----------LGGRLQAVVVENLNAAKKAIAFLKQNELGRvtflpl 578
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 909 QLRKENEKQKNELLSMEAEVCEKIGCLQRFKEMAIFKIAaLQKVVDNSVSLSELELANKQYNELTAKYRDI--------- 979
Cdd:TIGR02168 579 DSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA-LSYLLGGVLVVDDLDNALELAKKLRPGYRIVtldgdlvrp 657
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 980 --------LQKDNMLVQRTSNLEHLECENISLKEQVESINKELEITKEKLHTIEQAWEQETKLGNEssmdkakksitnsd 1051
Cdd:TIGR02168 658 ggvitggsAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE-------------- 723
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1052 ivsISKKITMLEMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELETKFAELTKiNLDAQKVEQMLRDELADSVSKAVS 1131
Cdd:TIGR02168 724 ---LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE-ELAEAEAEIEELEAQIEQLKEELK 799
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1132 dADRQRILELEKNEMELKVEVSKLRE-----ISDIARRQVEILNAQQQSRDK--EVESLRMQLLDYQAQSDEKSLIAKLH 1204
Cdd:TIGR02168 800 -ALREALDELRAELTLLNEEAANLRErleslERRIAATERRLEDLEEQIEELseDIESLAAEIEELEELIEELESELEAL 878
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462534488 1205 QHNV-SLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQAL--YYARLEGrnrakhLRQTIQSLRRQFS 1275
Cdd:TIGR02168 879 LNERaSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLaqLELRLEG------LEVRIDNLQERLS 946
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
93-868 |
3.86e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 65.85 E-value: 3.86e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 93 KLENELEMAQQSAGGRDTRFLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKK 172
Cdd:TIGR02168 217 ELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 173 NEQLCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEK 252
Cdd:TIGR02168 297 ISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEE 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 253 MTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELTD-LLKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEIIEYQQML 331
Cdd:TIGR02168 377 LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDrRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEEL 456
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 332 HNLREKLKNA--QLDADKSNVMALQQGIQERDSQIKMLTEQVEQYTKEMEKntcIIEDLKNELQRNKGASTLSQQthMKI 409
Cdd:TIGR02168 457 ERLEEALEELreELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEG---VKALLKNQSGLSGILGVLSEL--ISV 531
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 410 QSTLDILKEKTKEAERTAELAEADarEKDKELVEALKRLKDYESGVYGLEDA-----VVEIKNCKNQIKIRDREIEILTK 484
Cdd:TIGR02168 532 DEGYEAAIEAALGGRLQAVVVENL--NAAKKAIAFLKQNELGRVTFLPLDSIkgteiQGNDREILKNIEGFLGVAKDLVK 609
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 485 EINKLELKISDFL-------DENEALRERVGLEPKTMI---DLTEFRNSKHLKQQQYRAENQILL--KEIESLEEERLDL 552
Cdd:TIGR02168 610 FDPKLRKALSYLLggvlvvdDLDNALELAKKLRPGYRIvtlDGDLVRPGGVITGGSAKTNSSILErrREIEELEEKIEEL 689
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 553 KKKIR--QMAQERGKRSATSGLTTEDLNLTENISQGDRISERKLDLLSLKNMSE-AQSKNEFLSRELIEKERDLERSRTV 629
Cdd:TIGR02168 690 EEKIAelEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEqLEERIAQLSKELTELEAEIEELEER 769
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 630 IAKFQNKLKELVEENKQLEEGMKEILQAIKEMQKDPDVKGGETSLIIPSLERLVNAIESknaegifdaslhLKAQVDQLT 709
Cdd:TIGR02168 770 LEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLES------------LERRIAATE 837
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 710 GRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKE-TSLLRQSEGSNVvfkgidlpdgiapsSASIINSQNEYLIHLL 788
Cdd:TIGR02168 838 RRLEDLEEQIEELSEDIESLAAEIEELEELIEELESElEALLNERASLEE--------------ALALLRSELEELSEEL 903
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 789 QELENK----EKKLKNLEDSLEDYNRKFAVIRhQQSLLYKEYLSEKetWKTESKTIKEEKRKLEDQVQQDAIKVKEYNNL 864
Cdd:TIGR02168 904 RELESKrselRRELEELREKLAQLELRLEGLE-VRIDNLQERLSEE--YSLTLEEAEALENKIEDDEEEARRRLKRLENK 980
|
....
gi 2462534488 865 LNAL 868
Cdd:TIGR02168 981 IKEL 984
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
162-981 |
2.60e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.15 E-value: 2.60e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 162 LRRENKRLKKKNEQlCQDIIDYQKQIDSQKETLL-----SRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQN 236
Cdd:TIGR02168 198 LERQLKSLERQAEK-AERYKELKAELRELELALLvlrleELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEV 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 237 QEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELtdllKSKNEEDDPIMVAVNAKVEEWKLI 316
Cdd:TIGR02168 277 SELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEEL----ESKLDELAEELAELEEKLEELKEE 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 317 LSSKDDEIIEYQQMLHNLREKLK--NAQLDADKSNVMALQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQR 394
Cdd:TIGR02168 353 LESLEAELEELEAELEELESRLEelEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEE 432
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 395 NKGASTlsQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLED----------AVVE 464
Cdd:TIGR02168 433 AELKEL--QAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERlqenlegfseGVKA 510
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 465 IKNCKNQIK-IRDREIEILTKEiNKLELKISDFLDEN----------------EALRE----RVGLEPKTMIDLTEFRNS 523
Cdd:TIGR02168 511 LLKNQSGLSgILGVLSELISVD-EGYEAAIEAALGGRlqavvvenlnaakkaiAFLKQnelgRVTFLPLDSIKGTEIQGN 589
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 524 KHLKQQQYRAENQILLKEIESLEEERLDLKKKIRQMAQERGKRSATSGLTTEDLNLTENISQGDRISERKLdllSLKNMS 603
Cdd:TIGR02168 590 DREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGV---ITGGSA 666
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 604 EAQSKNEFLSRELIEKERDLERSRTVIAKFQNKLKELVEENKQLEEGMKEILQAIKEMQKDpdvkggetsliiPSLERLV 683
Cdd:TIGR02168 667 KTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQ------------ISALRKD 734
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 684 NAIESKNAEGIFDASLHLKAQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKETSLLRQsegsnvvfkgi 763
Cdd:TIGR02168 735 LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE----------- 803
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 764 dlpdgIAPSSASIINSQNEYLIHLLQELENKEKKLKNLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKET----------W 833
Cdd:TIGR02168 804 -----ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELieeleseleaL 878
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 834 KTESKTIKEEKRKLEDQVQQDAIKVKEYNNLLNALQMDSDEMKKILAENSRKITVLQVNEKSLIRQYTTLVELERQLRKE 913
Cdd:TIGR02168 879 LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEA 958
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462534488 914 NEkqkNELLSMEAEVCEKIGCLQRfkemaifKIAALQKVvdNSVSLSELELANKQYNELTAKYRDILQ 981
Cdd:TIGR02168 959 LE---NKIEDDEEEARRRLKRLEN-------KIKELGPV--NLAAIEEYEELKERYDFLTAQKEDLTE 1014
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
963-1888 |
3.92e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 62.47 E-value: 3.92e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 963 ELANKQYNELTAKYRDI--LQKDNM---LVQRTSNLEHLECENISLKE---QVESINKELEITKEKLHTIEQAWEQET-K 1033
Cdd:PTZ00121 1031 ELTEYGNNDDVLKEKDIidEDIDGNhegKAEAKAHVGQDEGLKPSYKDfdfDAKEDNRADEATEEAFGKAEEAKKTETgK 1110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1034 LGNESSMDKAKKSItnSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLRTS-LKQMEERNFELETKFAELTKINLDAQ 1112
Cdd:PTZ00121 1111 AEEARKAEEAKKKA--EDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEdARKAEEARKAEDAKKAEAARKAEEVR 1188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1113 KVEQMLRDELADSVSKAVSDADRQRILELEKNEMELKVEvsKLREISDIARRQVEilnAQQQSRDKEVESLRMQLLDYQA 1192
Cdd:PTZ00121 1189 KAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAE--AVKKAEEAKKDAEE---AKKAEEERNNEEIRKFEEARMA 1263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1193 QSDEKSLIAKLHQHNVSLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHLRQTIQSLRR 1272
Cdd:PTZ00121 1264 HFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKK 1343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1273 --QFSGALPLAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDTKGA---QKVINW 1347
Cdd:PTZ00121 1344 aaEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAaakKKADEA 1423
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1348 HMKIEELR-LQELKLNRELVKDKEEIKYLnniiSEYERTISSLEEEIVQQNKFHEERQMAWDQREVD-LERQLDIFDRQQ 1425
Cdd:PTZ00121 1424 KKKAEEKKkADEAKKKAEEAKKADEAKKK----AEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADeAKKKAEEAKKKA 1499
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1426 NEilnaAQKFEEATGSIPDPSLPLPNQLEIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINEL 1505
Cdd:PTZ00121 1500 DE----AKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEED 1575
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1506 RLRLPATAE-----REKLIAELGRKEMEPKSHHTLKIAHQTIANMQA-RLNQKEEVLKKYQRLLEKAREEQR--EIVKKH 1577
Cdd:PTZ00121 1576 KNMALRKAEeakkaEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAeELKKAEEEKKKVEQLKKKEAEEKKkaEELKKA 1655
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1578 EEDLHILHHRLELQADSSLNKFKQtawdlmkqsptpvptnkhfIRLAEMEQTVAEQddslssllvklkKVSQDLERQREI 1657
Cdd:PTZ00121 1656 EEENKIKAAEEAKKAEEDKKKAEE-------------------AKKAEEDEKKAAE------------ALKKEAEEAKKA 1704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1658 TELKVKEFENIKLQLQENHEDEVKKVKaeVEDLKYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRNLVERLKSQLALK 1737
Cdd:PTZ00121 1705 EELKKKEAEEKKKAEELKKAEEENKIK--AEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE 1782
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1738 E--KQQKALSRALLELRAEMTAAAEERIISATSQKEAHLN-VQQIVDRHTRELkTQVEDLNENLLKLKEALKTSKNRENS 1814
Cdd:PTZ00121 1783 EelDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINdSKEMEDSAIKEV-ADSKNMQLEEADAFEKHKFNKNNENG 1861
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2462534488 1815 LTDNLN-DLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQRKVKKLENQL 1888
Cdd:PTZ00121 1862 EDGNKEaDFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDKDEYIKRDAEETREEI 1936
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
27-743 |
5.14e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 62.00 E-value: 5.14e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 27 NLLISLSKVEVNELKSEKQEN------VIHLFRITQSLMKMK----AQEVELALEEVEKAGEEQAKFeNQLKTKVMKLEN 96
Cdd:TIGR02168 224 ELELALLVLRLEELREELEELqeelkeAEEELEELTAELQELeeklEELRLEVSELEEEIEELQKEL-YALANEISRLEQ 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 97 ELEMAQQSAggrdtRFLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQL 176
Cdd:TIGR02168 303 QKQILRERL-----ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEEL 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 177 CQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEanEKIEVQNQEMRKNLEESVQEMEKMTDE 256
Cdd:TIGR02168 378 EEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK--KLEEAELKELQAELEELEEELEELQEE 455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 257 YNRMKAIVHQTDNVIDQLKKENDHYQLQVQELT---DLLKSKNEEDDPIMVAVNAkVEEWKLILSSKDDEIIEyqqmLHN 333
Cdd:TIGR02168 456 LERLEEALEELREELEEAEQALDAAERELAQLQarlDSLERLQENLEGFSEGVKA-LLKNQSGLSGILGVLSE----LIS 530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 334 LREKLKNAQLDADKSNvmaLQQGIQERDSQIKMLTEQVEQytKEMEKNTCIIEDLKNElQRNKGASTLSQQTHMKIQSTL 413
Cdd:TIGR02168 531 VDEGYEAAIEAALGGR---LQAVVVENLNAAKKAIAFLKQ--NELGRVTFLPLDSIKG-TEIQGNDREILKNIEGFLGVA 604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 414 DILKEKTKEAER-----------TAELAEADAREKDKELVEALKRLKDY------------ESGVYGLEDAVVEIKNCKN 470
Cdd:TIGR02168 605 KDLVKFDPKLRKalsyllggvlvVDDLDNALELAKKLRPGYRIVTLDGDlvrpggvitggsAKTNSSILERRREIEELEE 684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 471 QIKIRDREIEILTKEINKLELKISDFLDENEALRERvGLEPKTMIDLTEFRNSKHL-KQQQYRAENQILLKEIESLEEER 549
Cdd:TIGR02168 685 KIEELEEKIAELEKALAELRKELEELEEELEQLRKE-LEELSRQISALRKDLARLEaEVEQLEERIAQLSKELTELEAEI 763
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 550 LDLKKKIRQMAQERGKRSATSGLTTEDLN-LTENISQGDRISerkldllslknmSEAQSKNEFLSRELIEKERDLERSRT 628
Cdd:TIGR02168 764 EELEERLEEAEEELAEAEAEIEELEAQIEqLKEELKALREAL------------DELRAELTLLNEEAANLRERLESLER 831
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 629 VIAKFQNKLKELVEENKQLEEGMKEILQAIKEMQKDPDVkggetslIIPSLERLVNAIESKNA--EGIFDASLHLKAQVD 706
Cdd:TIGR02168 832 RIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE-------LESELEALLNERASLEEalALLRSELEELSEELR 904
|
730 740 750
....*....|....*....|....*....|....*..
gi 2462534488 707 QLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHL 743
Cdd:TIGR02168 905 ELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
114-853 |
1.33e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 60.47 E-value: 1.33e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 114 RNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQL----ALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQK---Q 186
Cdd:TIGR02169 176 LEELEEVEENIERLDLIIDEKRQQLERLRREREKAeryqALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEeleK 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 187 IDSQKETLLSRRGEDSDYRSQLSKKNYELIQylDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQ 266
Cdd:TIGR02169 256 LTEEISELEKRLEEIEQLLEELNKKIKDLGE--EEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDK 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 267 TDNVIDQLKKENDHYQLQVQELTDLLKSKNEEDDPIMV---AVNAKVEEWKlilsskdDEIIEYQQMLHNLREKLKNAQL 343
Cdd:TIGR02169 334 LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAeleEVDKEFAETR-------DELKDYREKLEKLKREINELKR 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 344 DADKSNVMALQQGIQERD--SQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQRNKGASTLSQQTHMKIQSTLDILKEKTK 421
Cdd:TIGR02169 407 ELDRLQEELQRLSEELADlnAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELS 486
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 422 EAERTAELAEADAR---EKDKELVEALKRLKDYESGVYGLEDAVVEIK------------NCKNQIKIRDREIEILTKEI 486
Cdd:TIGR02169 487 KLQRELAEAEAQARaseERVRGGRAVEEVLKASIQGVHGTVAQLGSVGeryataievaagNRLNNVVVEDDAVAKEAIEL 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 487 NKlELKIS--DFLDENEALRERVGLEPKTM-------IDLTEFrnskhlkQQQYRAENQILLKE---IESLEEERlDLKK 554
Cdd:TIGR02169 567 LK-RRKAGraTFLPLNKMRDERRDLSILSEdgvigfaVDLVEF-------DPKYEPAFKYVFGDtlvVEDIEAAR-RLMG 637
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 555 KIRQMAQER-----------GKRSATSGLTTEDLNLTENISQGDRISERKLDLLSLKN--------MSEAQSKNEFLSRE 615
Cdd:TIGR02169 638 KYRMVTLEGelfeksgamtgGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSelrrienrLDELSQELSDASRK 717
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 616 LIEKERDLERSRTVIAKFQNKLKELVEENKQLEEGmkeiLQAIKEMQKDPDVKGGETSLIIPSLERLVNAIESKNAEgif 695
Cdd:TIGR02169 718 IGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQE----IENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH--- 790
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 696 daslhlkAQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKETSllrqsegsNVVFKGIDLPDGIAPSSAS 775
Cdd:TIGR02169 791 -------SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQ--------ELQEQRIDLKEQIKSIEKE 855
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462534488 776 IINSQNEyLIHLLQELENKEKKLKNLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKETWKTESKTIKEEKRKLEDQVQQ 853
Cdd:TIGR02169 856 IENLNGK-KEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE 932
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1640-1933 |
2.61e-08 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 59.57 E-value: 2.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1640 LLVKLKKVSQDLERQREITELKVKEFENIKLQLQEnHEDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQaqKEANSRAP 1719
Cdd:COG1196 230 LLLKLRELEAELEELEAELEELEAELEELEAELAE-LEAELEELRLELEELELELEEAQAEEYELLAELA--RLEQDIAR 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1720 TTTMRN----LVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRhTRELKTQVEDLN 1795
Cdd:COG1196 307 LEERRReleeRLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE-LAEAEEELEELA 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1796 ENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQgkpltdNKQSLIE 1875
Cdd:COG1196 386 EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA------ELEEEEE 459
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 2462534488 1876 ELQRKVKKLENQLEGKVEEV-DLKPMKEKNAKEELIRWEEGKKWQAKIEGIRNKLKEKE 1933
Cdd:COG1196 460 ALLELLAELLEEAALLEAALaELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1350-1944 |
1.36e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.37 E-value: 1.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1350 KIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQLDIFDRQQNEIL 1429
Cdd:TIGR02168 268 KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1430 NAAQKFEEATGSIPDPSLPLPN----------QLEIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRD 1499
Cdd:TIGR02168 348 ELKEELESLEAELEELEAELEElesrleeleeQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELL 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1500 KVINELRLRLPATAEREKLIAELGRKEMEPKSHHTLKIAHQTIANMQARLNQKEEVLKKY-------QRLLEKAREEQRE 1572
Cdd:TIGR02168 428 KKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLqarldslERLQENLEGFSEG 507
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1573 I--VKKHEEDLHILHHRL--------------------ELQA--DSSLNKFKQtAWDLMKQSPT------PVPTNKHFIR 1622
Cdd:TIGR02168 508 VkaLLKNQSGLSGILGVLselisvdegyeaaieaalggRLQAvvVENLNAAKK-AIAFLKQNELgrvtflPLDSIKGTEI 586
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1623 LAEMEQTVAEQDDSLSSLL------VKLKKVSQDL--------------ERQREITE----------------LKVKEFE 1666
Cdd:TIGR02168 587 QGNDREILKNIEGFLGVAKdlvkfdPKLRKALSYLlggvlvvddldnalELAKKLRPgyrivtldgdlvrpggVITGGSA 666
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1667 NIKLQLQENhEDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQA--QKEANSRAPTTTMRNLVERLKSQLALKEKQQKAL 1744
Cdd:TIGR02168 667 KTNSSILER-RREIEELEEKIEELEEKIAELEKALAELRKELEEleEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1745 SRALLELRAEMTAAAEERIISATSQKEAHLNVQqivdrhtrELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNN 1824
Cdd:TIGR02168 746 EERIAQLSKELTELEAEIEELEERLEEAEEELA--------EAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNE 817
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1825 ELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQG-KPLTDNKQSLIEELQRKVKKLENQLEGKVEEVDLKPMKEK 1903
Cdd:TIGR02168 818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESlAAEIEELEELIEELESELEALLNERASLEEALALLRSELE 897
|
650 660 670 680
....*....|....*....|....*....|....*....|....*....
gi 2462534488 1904 NAKEELIRWEEGKK--------WQAKIEGIRNKLKEKEGEVFTLTKQLN 1944
Cdd:TIGR02168 898 ELSEELRELESKRSelrreleeLREKLAQLELRLEGLEVRIDNLQERLS 946
|
|
| DUF1633 |
pfam07794 |
Protein of unknown function (DUF1633); This family contains sequences derived from a group of ... |
1765-1941 |
2.37e-07 |
|
Protein of unknown function (DUF1633); This family contains sequences derived from a group of hypothetical proteins expressed by Arabidopsis thaliana. These sequences are highly similar and the region concerned is about 100 residues long.
Pssm-ID: 116408 [Multi-domain] Cd Length: 698 Bit Score: 56.43 E-value: 2.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1765 SATSQKEAHLNVQQivdrhTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQ----KKQKAYNKILRek 1840
Cdd:pfam07794 458 RAIREEDPHLGADQ-----DREVRFGAEGIVPGIERLKIELSTSKDLEKGYAEKIGFMEMEFGgleaDKQMARNQIHR-- 530
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1841 eeIDQENDELKRQIKRLTSGLQG--KPLTDNK-------QSLIEELQRK--VKKLENQLEGKVEEVDLK-PMKEKNAKEE 1908
Cdd:pfam07794 531 --LEEKKDELSKKVLDLTSIAQGakKAVHDAKvelaaayLKLLAGIKDKwvAKKEFTVLEGQAAEVESNlALIDQITKAA 608
|
170 180 190
....*....|....*....|....*....|...
gi 2462534488 1909 LIRWEEGKKWQAKIEGIRNKLKEKEGEVFTLTK 1941
Cdd:pfam07794 609 IDLTLEKPRFQAEIDDLEARCKLKEVSDFTLSK 641
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
789-1371 |
3.52e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 56.30 E-value: 3.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 789 QELENKEKKLKNLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKETWKTESKTIKEEKRKLED--QVQQDAIKVKEYNNLLN 866
Cdd:PTZ00121 1246 EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEakKKAEEAKKADEAKKKAE 1325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 867 ALQMDSDEMKKILAENSRKITVLQVNEKSLIRQYTTLVELER--QLRKENEKQKNELLSMEAEVCEKIGCLQRFKEMAIF 944
Cdd:PTZ00121 1326 EAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEaaEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKK 1405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 945 KIAALQKVvdnsvslselELANKQYNELTAKYRDILQKDnmlvqrtsnlehleceniSLKEQVESINKELEItKEKLHTI 1024
Cdd:PTZ00121 1406 KADELKKA----------AAAKKKADEAKKKAEEKKKAD------------------EAKKKAEEAKKADEA-KKKAEEA 1456
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1025 EQAWEQETKLGNESSMDKAKKSITNSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLRTSlkqmEERNFELETKFAEL 1104
Cdd:PTZ00121 1457 KKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKA----EEAKKADEAKKAEE 1532
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1105 TKINLDAQKVEQMLRdelADSVSKAVsdadrqrilELEKNEMELKVE-VSKLREISDIARRQVEILNAQQQSRDKEVESL 1183
Cdd:PTZ00121 1533 AKKADEAKKAEEKKK---ADELKKAE---------ELKKAEEKKKAEeAKKAEEDKNMALRKAEEAKKAEEARIEEVMKL 1600
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1184 RMQLLDYQAQSDEKSLIAKLHQHNVSLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHL 1263
Cdd:PTZ00121 1601 YEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEA 1680
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1264 RQTIQSLRRQFSGALPLAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNM--ENKTLEMELKLKGLEELISTLKDTKGA 1341
Cdd:PTZ00121 1681 KKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKaeEAKKEAEEDKKKAEEAKKDEEEKKKIA 1760
|
570 580 590
....*....|....*....|....*....|
gi 2462534488 1342 QKVINWHMKIEELRLQELKLNRELVKDKEE 1371
Cdd:PTZ00121 1761 HLKKEEEKKAEEIRKEKEAVIEEELDEEDE 1790
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1236-1857 |
4.42e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 55.71 E-value: 4.42e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1236 LRLEQKLDEKEQALYYARLEG-RNRAKHLRQTIQSLRRQFSGALplAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNM 1314
Cdd:COG1196 216 RELKEELKELEAELLLLKLRElEAELEELEAELEELEAELEELE--AELAELEAELEELRLELEELELELEEAQAEEYEL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1315 ENKTLEMELKLKGLEELISTLKDTKGAQKVinwhmKIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIV 1394
Cdd:COG1196 294 LAELARLEQDIARLEERRRELEERLEELEE-----ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1395 QQNKFHEERQMAWDQREVDLERQLDIFDRQQNEILNAAQKFEEATgsipdpslplpNQLEIALRKIKENIRIILETRATC 1474
Cdd:COG1196 369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL-----------ERLERLEEELEELEEALAELEEEE 437
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1475 KSLEEKLKEKESALRLAEQNILSRDKVINELRLRLpatAEREKLIAELGRKEMEPKSHHTLKIAHQtiANMQARLNQ-KE 1553
Cdd:COG1196 438 EEEEEALEEAAEEEAELEEEEEALLELLAELLEEA---ALLEAALAELLEELAEAAARLLLLLEAE--ADYEGFLEGvKA 512
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1554 EVLKKYQRLLEKAREEQREIVKKHEEDLHILHHRLELQADSSLNKFKQTAWDLMKQSPTPVPTnkhFIRLAEMEQTVAEQ 1633
Cdd:COG1196 513 ALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAT---FLPLDKIRARAALA 589
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1634 DDSLSSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQSQKESQcLKSELQAQKE 1713
Cdd:COG1196 590 AALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA-GGSLTGGSRR 668
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1714 ANSRAptttmRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRHTRELKTQVED 1793
Cdd:COG1196 669 ELLAA-----LLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE 743
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462534488 1794 LNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQK-------AYNKILREKEEIDQENDELKRQIKRL 1857
Cdd:COG1196 744 EEELLEEEALEELPEPPDLEELERELERLEREIEALGPvnllaieEYEELEERYDFLSEQREDLEEARETL 814
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
243-563 |
8.57e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 54.69 E-value: 8.57e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 243 LEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELTDLLKSKNEEDDpimvAVNAKVEEWKLILSSKDD 322
Cdd:TIGR02169 676 LQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEE----KLKERLEELEEDLSSLEQ 751
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 323 EIIEYQQMLHNLREKLknAQLDADKSNVMALQQGIQ--ERDSQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQRNKGAST 400
Cdd:TIGR02169 752 EIENVKSELKELEARI--EELEEDLHKLEEALNDLEarLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE 829
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 401 LSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVVEIKNCKNQIKIRDRE-- 478
Cdd:TIGR02169 830 YLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEEle 909
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 479 --IEILTKEINKLELKISDFLDENEALRERVGL---EPKTMIDLTEFRNSKHLKQQQYRAENQILLKEIESLEEE---RL 550
Cdd:TIGR02169 910 aqIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVlkrLD 989
|
330
....*....|...
gi 2462534488 551 DLKKKIRQMAQER 563
Cdd:TIGR02169 990 ELKEKRAKLEEER 1002
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1219-1992 |
8.89e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 54.68 E-value: 8.89e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1219 GKLESITSKLQKMEAYnLRLEQKLDEKEQALYYARLEGRNraKHLRQTIQSLRRQfsgalplaqQEKFSKTMIQLQNDKL 1298
Cdd:TIGR02168 200 RQLKSLERQAEKAERY-KELKAELRELELALLVLRLEELR--EELEELQEELKEA---------EEELEELTAELQELEE 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1299 KIMQEMKnsqqEHRNMENKTLEMELKLKGLEELISTLKDTKGAQKV--INWHMKIEELRLQELKLNRELVKDKEEIKYLN 1376
Cdd:TIGR02168 268 KLEELRL----EVSELEEEIEELQKELYALANEISRLEQQKQILRErlANLERQLEELEAQLEELESKLDELAEELAELE 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1377 NIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQLDIFDRQQNEILNAAQKFEEATGSIPD------------ 1444
Cdd:TIGR02168 344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERledrrerlqqei 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1445 ---PSLPLPNQLEIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAEREkliae 1521
Cdd:TIGR02168 424 eelLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQ----- 498
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1522 lGRKEMEPKSHHTLKIAHQTIANMQARLNQKEEVLKKYQRLLEKAREEQRE-IVKKHEEDLhilhhRLELQADSSLNKFK 1600
Cdd:TIGR02168 499 -ENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQaVVVENLNAA-----KKAIAFLKQNELGR 572
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1601 QTAWDLMKQSPTPVPTNKHFIR---------LAEMEQTVAEQDDSLSSLLVKL--------------------------- 1644
Cdd:TIGR02168 573 VTFLPLDSIKGTEIQGNDREILkniegflgvAKDLVKFDPKLRKALSYLLGGVlvvddldnalelakklrpgyrivtldg 652
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1645 --------------KKVSQDLERQREITELKvkefENIKLQLQENHE--DEVKKVKAEVEDLKYLLDQSQKESQCLKSEL 1708
Cdd:TIGR02168 653 dlvrpggvitggsaKTNSSILERRREIEELE----EKIEELEEKIAEleKALAELRKELEELEEELEQLRKELEELSRQI 728
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1709 QAQKEansraptttmrnLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAhlnvqqivdrhtrelK 1788
Cdd:TIGR02168 729 SALRK------------DLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA---------------E 781
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1789 TQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQG-KPLT 1867
Cdd:TIGR02168 782 AEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESlAAEI 861
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1868 DNKQSLIEELQRKVKKLENQLEGKVEEVDLKPMKEKNAKEELIRWEEGKK--------WQAKIEGIRNKLKEKEGEVFTL 1939
Cdd:TIGR02168 862 EELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSelrreleeLREKLAQLELRLEGLEVRIDNL 941
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462534488 1940 TKQLN--------TLKDLFAKADKEKLTLQRKLKTTGMTVDQvLGIRALESEKELEELKKR 1992
Cdd:TIGR02168 942 QERLSeeysltleEAEALENKIEDDEEEARRRLKRLENKIKE-LGPVNLAAIEEYEELKER 1001
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
206-559 |
9.43e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 54.68 E-value: 9.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 206 SQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQV 285
Cdd:TIGR02168 691 EKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERL 770
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 286 QELTDLLKSKNEEddpiMVAVNAKVEEWKLILSSKDDEIIEYQQMLHNLREKLKNAQLDADKS--NVMALQQGIQERDSQ 363
Cdd:TIGR02168 771 EEAEEELAEAEAE----IEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLerRIAATERRLEDLEEQ 846
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 364 IKMLTEQVEQYTKEMEKNTCIIEDLKNELQRNKGASTLSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELVE 443
Cdd:TIGR02168 847 IEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQ 926
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 444 ALKRLKDYESGVYGLEDAVVEikncknQIKIRDREIEILTKEINKLELKISDFLDENEALRERVGlePKTMIDLTEFrns 523
Cdd:TIGR02168 927 LELRLEGLEVRIDNLQERLSE------EYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELG--PVNLAAIEEY--- 995
|
330 340 350
....*....|....*....|....*....|....*.
gi 2462534488 524 khlkqQQYRAENQILLKEIESLEEERLDLKKKIRQM 559
Cdd:TIGR02168 996 -----EELKERYDFLTAQKEDLTEAKETLEEAIEEI 1026
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
21-661 |
1.07e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 54.17 E-value: 1.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 21 QEELADNLLISLSKVEVNELKSEKQENVIHLFRITQSLMKMKAQEVELALEEVEKAGEEQAKFEnQLKTKVMKLENELEM 100
Cdd:COG1196 221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE-EAQAEEYELLAELAR 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 101 AQQsaggrDTRFLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDI 180
Cdd:COG1196 300 LEQ-----DIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 181 IDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRM 260
Cdd:COG1196 375 AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 261 KAIVHQTDNVIDQLKKENDHYQLQVQELTDLL---KSKNEEDDPIMVAVNAKVEEWKLILSSKDDEIIEyqQMLHNLREK 337
Cdd:COG1196 455 EEEEEALLELLAELLEEAALLEAALAELLEELaeaAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA--GAVAVLIGV 532
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 338 LKNAQLDADKSNVMALQQGIQERDSQIKMLteqveqytkemekntciIEDLKnelQRNKGASTLSQQTHMKIQSTLDILK 417
Cdd:COG1196 533 EAAYEAALEAALAAALQNIVVEDDEVAAAA-----------------IEYLK---AAKAGRATFLPLDKIRARAALAAAL 592
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 418 EKTKEAERTAELAEadarekdkELVEALKRLKDYESGVYGLEDAVVEIKNCKNQIKIRDREIEILTKEINKLELKISDFL 497
Cdd:COG1196 593 ARGAIGAAVDLVAS--------DLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTG 664
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 498 DENEALRERVGLEPKTMIDLTEFRNSKHLKQQQYRAENQILLKEIESLEEERLDLKKKIRQMAQErgkrsatsgLTTEDL 577
Cdd:COG1196 665 GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQ---------LEAERE 735
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 578 NLTENISQGDRISERKLDLLSLKNMSEAQsknefLSRELIEKERDLERSRTV----IAKF---QNKLKELVEENKQLEEG 650
Cdd:COG1196 736 ELLEELLEEEELLEEEALEELPEPPDLEE-----LERELERLEREIEALGPVnllaIEEYeelEERYDFLSEQREDLEEA 810
|
650
....*....|.
gi 2462534488 651 MKEILQAIKEM 661
Cdd:COG1196 811 RETLEEAIEEI 821
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
963-1272 |
2.69e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.02 E-value: 2.69e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 963 ELANKQYNELTAKYRDILQKdnmLVQRTSNLEHLECENISLKEQVESINKELEITKEKLHTIEQAWEQEtklgnessmdK 1042
Cdd:COG1196 221 ELKELEAELLLLKLRELEAE---LEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEA----------Q 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1043 AKKSITNSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELETKFAELTKINLDAQKVEQMLRDEL 1122
Cdd:COG1196 288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1123 ADSVSKAVS-----DADRQRILELEKNEMELKVEVSKL-REISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDE 1196
Cdd:COG1196 368 LEAEAELAEaeeelEELAEELLEALRAAAELAAQLEELeEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462534488 1197 KSLIAKLHQHNVSLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQALyyARLEGRNRAKHLRQTIQSLRR 1272
Cdd:COG1196 448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE--ADYEGFLEGVKAALLLAGLRG 521
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
269-1092 |
5.05e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.37 E-value: 5.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 269 NVIDQLKKENDHYQLQVQELTDLLKSKNEEddpiMVAVNAKVEEWKLILSSKDDEIIEYQQMLHNLREKlknaqldadks 348
Cdd:TIGR02168 232 LRLEELREELEELQEELKEAEEELEELTAE----LQELEEKLEELRLEVSELEEEIEELQKELYALANE----------- 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 349 nvmalqqgIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQRNKGAstlsqqthmkiqstLDILKEKTKEAERTAE 428
Cdd:TIGR02168 297 --------ISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEE--------------LAELEEKLEELKEELE 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 429 LAEADAREKDKELVEALKRLKDYESGVYGLEDAVVEIKNCKNQIKIrdrEIEILTKEINKLELKISDFLDENEALRERVG 508
Cdd:TIGR02168 355 SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN---EIERLEARLERLEDRRERLQQEIEELLKKLE 431
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 509 LEPKTMI--DLTEFRNSKHLKQQQYRAENQILLKEIESLEEERLDLKKKIRQMAQERGKRSAT-------SGLTTEDLNL 579
Cdd:TIGR02168 432 EAELKELqaELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLerlqenlEGFSEGVKAL 511
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 580 TENISQGDRISERKLDLLSLKNMSEAQ-------------SKNEFLSRELIE--KERDLERsRTVIAKFQNKLKELVEEN 644
Cdd:TIGR02168 512 LKNQSGLSGILGVLSELISVDEGYEAAieaalggrlqavvVENLNAAKKAIAflKQNELGR-VTFLPLDSIKGTEIQGND 590
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 645 KQLEEGMKEILQAIKEMQK-DPDVKGG-----ETSLIIPSLERLVNAIESKNAEG-IFDASLHLKAQVDQLTGRNEELRQ 717
Cdd:TIGR02168 591 REILKNIEGFLGVAKDLVKfDPKLRKAlsyllGGVLVVDDLDNALELAKKLRPGYrIVTLDGDLVRPGGVITGGSAKTNS 670
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 718 ELRESRKEAINYSQQLAKANLKIDHLEKETSLLRQsEGSNVVFKGIDLPDGIAPSSASIiNSQNEYLIHLLQELENKEKK 797
Cdd:TIGR02168 671 SILERRREIEELEEKIEELEEKIAELEKALAELRK-ELEELEEELEQLRKELEELSRQI-SALRKDLARLEAEVEQLEER 748
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 798 LKNLEDSLEDYNRKFAvirhqqsllykEYLSEKETWKTESKTIKEEKRKLEDQVQQDAIKVKEYNNLLNALQMDSDEMKK 877
Cdd:TIGR02168 749 IAQLSKELTELEAEIE-----------ELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNE 817
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 878 ILAENSRKitvLQVNEKSLIRQYTTLVELERQLRKENEkqknELLSMEAEVCEkigcLQRFKEMAIFKIAALQKVVDnsV 957
Cdd:TIGR02168 818 EAANLRER---LESLERRIAATERRLEDLEEQIEELSE----DIESLAAEIEE----LEELIEELESELEALLNERA--S 884
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 958 SLSELELANKQYNELTAKYRDILQKdnmlvqrtsnLEHLECENISLKEQVESINKELEITKEKL-HTIEQAWEQ------ 1030
Cdd:TIGR02168 885 LEEALALLRSELEELSEELRELESK----------RSELRRELEELREKLAQLELRLEGLEVRIdNLQERLSEEysltle 954
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462534488 1031 ---ETKLGNESSMDKAKKSITnsdivSISKKITML---------EMKELNERQraEHCQKMYEHLRTSLKQMEE 1092
Cdd:TIGR02168 955 eaeALENKIEDDEEEARRRLK-----RLENKIKELgpvnlaaieEYEELKERY--DFLTAQKEDLTEAKETLEE 1021
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1584-1856 |
6.15e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.84 E-value: 6.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1584 LHHRLELQADSSLNKFKQTawdlmkQSPTPVPTNKHFIRlAEM--EQTVAEQDDSLSSLLVKLKKVSQDLERQREitelK 1661
Cdd:COG4913 182 LRRRLGIGSEKALRLLHKT------QSFKPIGDLDDFVR-EYMleEPDTFEAADALVEHFDDLERAHEALEDARE----Q 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1662 VKEFEniklQLQENHEdEVKKVKAEVEDLKYLLDQSQKESQCLKSELQAQKEANSRAptttmrnLVERLKSQLALKEKQQ 1741
Cdd:COG4913 251 IELLE----PIRELAE-RYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRA-------ELARLEAELERLEARL 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1742 KALSRALLELRAEMT-------AAAEERIISATSQKEAHLNVQQIVDRHTRELKTQV----EDLNENLLKLKEALKTSKN 1810
Cdd:COG4913 319 DALREELDELEAQIRgnggdrlEQLEREIERLERELEERERRRARLEALLAALGLPLpasaEEFAALRAEAAALLEALEE 398
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 2462534488 1811 RENSLTDNLNDLNNELQKKQKAYNKILREKEE-------IDQENDELKRQIKR 1856
Cdd:COG4913 399 ELEALEEALAEAEAALRDLRRELRELEAEIASlerrksnIPARLLALRDALAE 451
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
87-739 |
8.35e-06 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 51.27 E-value: 8.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 87 LKTKVMKLENELEMAQQSAGGRDTRFLRNEICQLEKQLEQKDREL----EDMEKELEKEKKVNEQLALRNEEAENENSKL 162
Cdd:pfam15921 236 LKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEItgltEKASSARSQANSIQSQLEIIQEQARNQNSMY 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 163 RRENKRLKKKNEQLCQDIIDYQKQIDSQKETLlsrrgedsdyRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKN 242
Cdd:pfam15921 316 MRQLSDLESTVSQLRSELREAKRMYEDKIEEL----------EKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLAD 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 243 LEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELTDLLKSKNEEDDPIMvavnakveewklilsskdd 322
Cdd:pfam15921 386 LHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQM------------------- 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 323 eiiEYQqmlhnlreklknaqldadksnvMALQQGIQERDSQIKMLTEQVEQyTKEMEKNtcIIEDLknelqrnkgasTLS 402
Cdd:pfam15921 447 ---ERQ----------------------MAAIQGKNESLEKVSSLTAQLES-TKEMLRK--VVEEL-----------TAK 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 403 QQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVVEIKNCKNQIKIRDREIEIL 482
Cdd:pfam15921 488 KMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEIL 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 483 TKEI-NKLELKISDFLDENEALRERVGLEPKTMIDLTEFRNSKHLKQQQyRAENQILLKEIESLEEERLDLK-------K 554
Cdd:pfam15921 568 RQQIeNMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKK-DAKIRELEARVSDLELEKVKLVnagserlR 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 555 KIRQMAQERGKRSATSGLTTEDLNlteNISQGDRISERkldllSLKNMSEA-QSKNEFLSRELIEKERDLERSRTVIakf 633
Cdd:pfam15921 647 AVKDIKQERDQLLNEVKTSRNELN---SLSEDYEVLKR-----NFRNKSEEmETTTNKLKMQLKSAQSELEQTRNTL--- 715
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 634 qnklkelveenKQLEEGMKEILQAIKEMQKDPDVKGGETSLIIPSLERLVNAIESKNAEGIFDASLHLK---------AQ 704
Cdd:pfam15921 716 -----------KSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKlsqelstvaTE 784
|
650 660 670
....*....|....*....|....*....|....*
gi 2462534488 705 VDQLTGRNEELRQELRESRKEAINYSQQLAKANLK 739
Cdd:pfam15921 785 KNKMAGELEVLRSQERRLKEKVANMEVALDKASLQ 819
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
230-975 |
9.01e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.22 E-value: 9.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 230 EKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKEndhYQLQVQELTDLLKSKNEEDDPIMVAVNAK 309
Cdd:TIGR02169 219 EKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKR---LEEIEQLLEELNKKIKDLGEEEQLRVKEK 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 310 VEEWKLILSSKDDEIIEYQQMLHNLREKLKNAQLDADKsnvmaLQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLK 389
Cdd:TIGR02169 296 IGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDK-----LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLR 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 390 NELQRNKGASTLSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLEDavveiknck 469
Cdd:TIGR02169 371 AELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEE--------- 441
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 470 nqikirdrEIEILTKEINKLELKISDFLDENEALRERVglepktmidltefrnskhlkqQQYRAENQILLKEIESLEEER 549
Cdd:TIGR02169 442 --------EKEDKALEIKKQEWKLEQLAADLSKYEQEL---------------------YDLKEEYDRVEKELSKLQREL 492
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 550 LDLKKKIRQMAQERGKRSATSGLTTEDLN-LTENISQGDRISER-----------KLDLLSLKNMSEAQSKNEFLSRELI 617
Cdd:TIGR02169 493 AEAEAQARASEERVRGGRAVEEVLKASIQgVHGTVAQLGSVGERyataievaagnRLNNVVVEDDAVAKEAIELLKRRKA 572
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 618 --------EKERDLERSRTVIAK--FQNKLKELVEENKQLEEGMKEILQ---AIKEMQKDPDVKGG------ETSLIIPS 678
Cdd:TIGR02169 573 gratflplNKMRDERRDLSILSEdgVIGFAVDLVEFDPKYEPAFKYVFGdtlVVEDIEAARRLMGKyrmvtlEGELFEKS 652
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 679 LERLVNAIESKNAEGI----FDASLHLKAQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKETSLLRQSE 754
Cdd:TIGR02169 653 GAMTGGSRAPRGGILFsrsePAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEE 732
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 755 GSNvvfkgidlpdgiapssASIINSQNEYLIHLLQELENKEKKLKNLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKetwk 834
Cdd:TIGR02169 733 EKL----------------KERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSR---- 792
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 835 teSKTIKEEKRKLEDQVQQDAIKVKEYNNLLNALQMDSDEMKKILAENSRKITVLQVNEKSLIRQYTTLVELERQLRKEN 914
Cdd:TIGR02169 793 --IPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEEL 870
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462534488 915 EKQKNELLSMEaevcEKIGCLQRFKEMAIFKIAALQKVVDNSVslSELELANKQYNELTAK 975
Cdd:TIGR02169 871 EELEAALRDLE----SRLGDLKKERDELEAQLRELERKIEELE--AQIEKKRKRLSELKAK 925
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1554-1863 |
9.56e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 51.09 E-value: 9.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1554 EVLKKYQRLLEKAREEQREIVKKHEEDLHILHHRLELQADSSLNKFKQTAWDLMKQSptpvptnkhfIRLAEMEQTVAEQ 1633
Cdd:COG1196 210 EKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELE----------AELEELRLELEEL 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1634 DDSLSSLLVKLKKVSQD---LERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQA 1710
Cdd:COG1196 280 ELELEEAQAEEYELLAElarLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1711 QKEANSRAPTTTmRNLVERLKSQLALKEKQQKALSRALLELRAEmtAAAEERIISATSQKEAHLNVQQIVDRHTRELKTQ 1790
Cdd:COG1196 360 LAEAEEALLEAE-AELAEAEEELEELAEELLEALRAAAELAAQL--EELEEAEEALLERLERLEEELEELEEALAELEEE 436
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462534488 1791 VEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQG 1863
Cdd:COG1196 437 EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEG 509
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
608-927 |
1.16e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 51.09 E-value: 1.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 608 KNEFLSRELIEKERDLERSRTVIAKFQNKLKELVEENKQLEEGMKEILQAIKEMQKDPDVKGGETSLIIPSLERLVNAIE 687
Cdd:COG1196 226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 688 sknaegifdaslHLKAQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKETSLLRQSegsnvvfkgidlpd 767
Cdd:COG1196 306 ------------RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE-------------- 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 768 giapssasiinsqneyLIHLLQELENKEKKLKNLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKEtwktESKTIKEEKRKL 847
Cdd:COG1196 360 ----------------LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE----AEEALLERLERL 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 848 EDQVQQDAIKVKEYNNLLNALQMDSDEMKKILAENSRKITVLQVNEKSLIRQYTTLVELERQLRKENEKQKNELLSMEAE 927
Cdd:COG1196 420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
1065-1895 |
2.22e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 50.12 E-value: 2.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1065 KELNERQRAEHCQKMYehLRTSLkqmeernFELETKFAELtkinldaqkveQMLRDELADsVSKAVSDADRQRILELEKN 1144
Cdd:pfam15921 92 RRLNESNELHEKQKFY--LRQSV-------IDLQTKLQEM-----------QMERDAMAD-IRRRESQSQEDLRNQLQNT 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1145 EMELKVEVSKLREISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKsliakLHQHNvSLQLSEATALGKleSI 1224
Cdd:pfam15921 151 VHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKK-----IYEHD-SMSTMHFRSLGS--AI 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1225 TSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHLRQTIQSLRRQFSGALPL---AQQEKFSKTMIQLQNdklkIM 1301
Cdd:pfam15921 223 SKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVeitGLTEKASSARSQANS----IQ 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1302 QEMKNSQQEHRNMENKTLEmelKLKGLEELISTLKDTKGAQKVInWHMKIEELRLQELKLNRELVKDKEEIKYLN----N 1377
Cdd:pfam15921 299 SQLEIIQEQARNQNSMYMR---QLSDLESTVSQLRSELREAKRM-YEDKIEELEKQLVLANSELTEARTERDQFSqesgN 374
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1378 IISEYERTISSLEEEIVQQNKFHEERQMAWDqREVDLERQLDIFDRQQNEILNAAQKFEEATGSIPDPSLPLPNQLEIAL 1457
Cdd:pfam15921 375 LDDQLQKLLADLHKREKELSLEKEQNKRLWD-RDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAI 453
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1458 RKIKENIRIILETRATCKSLEEKLKekesalrlaeqnilsrdkvinelrlrlpataereKLIAELGRKEMepkshhTLKI 1537
Cdd:pfam15921 454 QGKNESLEKVSSLTAQLESTKEMLR----------------------------------KVVEELTAKKM------TLES 493
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1538 AHQTIANMQARLNQKEEVLKKYQRLLEKARE----EQREIVKKHEEDLHILHHRLELQADSSLNKFKQTAWDLMKQsptp 1613
Cdd:pfam15921 494 SERTVSDLTASLQEKERAIEATNAEITKLRSrvdlKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQ---- 569
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1614 vptnkhfiRLAEMEQTVAEQDDSLSSLLVKLKKVSQDL-ERQREITELKV------KEFENIKLQLQENHEDEVKKVKAE 1686
Cdd:pfam15921 570 --------QIENMTQLVGQHGRTAGAMQVEKAQLEKEInDRRLELQEFKIlkdkkdAKIRELEARVSDLELEKVKLVNAG 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1687 VEDLKYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRNLVERLKSqlalkEKQQKALSRALLELRAEMTAAAEER-IIS 1765
Cdd:pfam15921 642 SERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKS-----EEMETTTNKLKMQLKSAQSELEQTRnTLK 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1766 ATSQKEAH-LNVQQIVDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEID 1844
Cdd:pfam15921 717 SMEGSDGHaMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLR 796
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|..
gi 2462534488 1845 QENDELKRQIKRLTSGLQGKPLTDNK-QSLIEELQRKVKKLENQLEGKVEEV 1895
Cdd:pfam15921 797 SQERRLKEKVANMEVALDKASLQFAEcQDIIQRQEQESVRLKLQHTLDVKEL 848
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
356-752 |
3.65e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 49.30 E-value: 3.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 356 GIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQRnkgastlsqqthmkiqstldiLKEKTKEAERTAELAEadaR 435
Cdd:TIGR02169 164 GVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLER---------------------LRREREKAERYQALLK---E 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 436 EKDKELVEALKRLKDYESgvygledavveikncknQIKIRDREIEILTKEINKLELKISDFLDENEALRERVGLEPKTMI 515
Cdd:TIGR02169 220 KREYEGYELLKEKEALER-----------------QKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIK 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 516 DLTEfrnskhlkqqqyrAENQILLKEIESLEEERLDLKKKIRQMAQERGKRSATSGLTTEDLnltenisqgDRISERKLD 595
Cdd:TIGR02169 283 DLGE-------------EEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEI---------DKLLAEIEE 340
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 596 LlsLKNMSEAQSKNEFLSRELIEKERDLERSRTVIAKFQNKLKELVEENKQLEEGMKEILQAIKEMQKDPDVKGGETSLI 675
Cdd:TIGR02169 341 L--EREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRL 418
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2462534488 676 IPSLERLVNAIesknaEGIFDASLHLKAQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKETSLLRQ 752
Cdd:TIGR02169 419 SEELADLNAAI-----AGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQR 490
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1736-2333 |
4.09e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 49.16 E-value: 4.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1736 LKEKQQKALSRALLELRAEMTAAAEEriISATSQKEAHLNVQQivdrhtRELKTQVEDLNENLLKLKEALKTSKNRENSL 1815
Cdd:COG1196 222 LKELEAELLLLKLRELEAELEELEAE--LEELEAELEELEAEL------AELEAELEELRLELEELELELEEAQAEEYEL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1816 TDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLtsglqgkpltdnkQSLIEELQRKVKKLENQLEGKVEEV 1895
Cdd:COG1196 294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL-------------EEELEELEEELEEAEEELEEAEAEL 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1896 DLKPMKEKNAKEELIRWEEG-KKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKEKLTLQRKLKTTGMTVDQV 1974
Cdd:COG1196 361 AEAEEALLEAEAELAEAEEElEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE 440
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1975 LgIRALESEKELEELKKRNLDLENDILYMRAHQALPRDSVVEDLHLQNRYLQEKLHALEKQFSKDTYSKPSISGIESDDH 2054
Cdd:COG1196 441 E-EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGL 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2055 CQREQELQKENLKlsseniELKFQLEQANKDLPRLKNQVR----DLKEMCEFLKkekaevQRKLGHVRGAELEKLKAHLG 2130
Cdd:COG1196 520 RGLAGAVAVLIGV------EAAYEAALEAALAAALQNIVVeddeVAAAAIEYLK------AAKAGRATFLPLDKIRARAA 587
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2131 HQLSMHYESKTKGTEKIIAENERLRKELKKETDAAEKLRIAKNNLEILNEKMTVQLEETGKRLQFAESRGPQLegadsks 2210
Cdd:COG1196 588 LAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG------- 660
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2211 wksivvtRMYETKLKELETDIAKKNQSITDLKQLVKEAtEREQKVNKYNEDLEQQIKILKHVPEGAETEQGLKRELQVLR 2290
Cdd:COG1196 661 -------SLTGGSRRELLAALLEAEAELEELAERLAEE-ELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA 732
|
570 580 590 600
....*....|....*....|....*....|....*....|...
gi 2462534488 2291 LANHQLDKEKAELIHQIEANKDqsgAESTIPDADQLKEKIKDL 2333
Cdd:COG1196 733 EREELLEELLEEEELLEEEALE---ELPEPPDLEELERELERL 772
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
75-486 |
4.56e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.90 E-value: 4.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 75 KAGEEQAKFENQLKTKVMKLENELEMaqqsaggrdtrfLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEE 154
Cdd:TIGR02168 684 EKIEELEEKIAELEKALAELRKELEE------------LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 155 AENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEV 234
Cdd:TIGR02168 752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLER 831
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 235 QNQEMRKNLEESVQEMEKMTDEynrMKAIVHQtdnvIDQLKKENDHYQLQVQELTDLLKSKNEEddpiMVAVNAKVEEWK 314
Cdd:TIGR02168 832 RIAATERRLEDLEEQIEELSED---IESLAAE----IEELEELIEELESELEALLNERASLEEA----LALLRSELEELS 900
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 315 LILSSKDDEIIEYQQMLHNLREKLKNAQLDadksnvmaLQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQR 394
Cdd:TIGR02168 901 EELRELESKRSELRRELEELREKLAQLELR--------LEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARR 972
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 395 NkgastlsqqthmkiqstLDILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVVEIkncknqiki 474
Cdd:TIGR02168 973 R-----------------LKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEI--------- 1026
|
410
....*....|..
gi 2462534488 475 rDREIEILTKEI 486
Cdd:TIGR02168 1027 -DREARERFKDT 1037
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1640-2411 |
9.57e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 48.04 E-value: 9.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1640 LLVKLKKVSQDLERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVEdlkylLDQSQKESQCLKSELQAQKEANSRAP 1719
Cdd:pfam02463 227 LYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENK-----EEEKEKKLQEEELKLLAKEEEELKSE 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1720 TTTMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRHTRELktqvEDLNENLL 1799
Cdd:pfam02463 302 LLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLE----QLEEELLA 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1800 KLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQR 1879
Cdd:pfam02463 378 KKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQE 457
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1880 KvKKLENQLEGKVEEVDLKPMKEKNAKEELIRWEEGKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKEKLT 1959
Cdd:pfam02463 458 L-KLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGV 536
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1960 LQRKLKTTGMTVDQVLGIRALESEKELEELKKRNLDLENDILYMRAHQALPRDSVVEDLHLQNRYLQEKLHALEKQFSKD 2039
Cdd:pfam02463 537 AVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEAD 616
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2040 TYSK--PSISGIESDDHCQREQELQKENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKEMCEFLKKEKAEVQRKLGHV 2117
Cdd:pfam02463 617 EDDKraKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILR 696
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2118 RGAELEKLKAHLGHQLSMHYESKTKGtekiiaENERLRKELKKETDAAEKLRIAKNNLEILNEKMTVQLEETGKRLQFAE 2197
Cdd:pfam02463 697 RQLEIKKKEQREKEELKKLKLEAEEL------LADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELS 770
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2198 SRGPQLEGADSKSWKSIVVTRMYETKLKELETDIAKKNQSITDLKQLVKEATEREQKVNKYNEDLEQQIKILKHVPEGAE 2277
Cdd:pfam02463 771 LKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEK 850
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2278 TEQGLKRELQVLRLANHQLDKEKAELIHQIEANKDQSGAESTipDADQLKEKIKDLETQLKMSDLEKQHLKEEIKKLKKE 2357
Cdd:pfam02463 851 LAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKE--EKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAE 928
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*
gi 2462534488 2358 LENFDPSFFEEIEDLKYNYKEEVKKNILLEEKVKKLSEQLGVELTSPVA-ASEEF 2411
Cdd:pfam02463 929 ILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLmAIEEF 983
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
34-428 |
1.11e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.83 E-value: 1.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 34 KVEVNELKSEKQENVIHLFRITQSLMKMKAQEVELALEEVEKAGEEQAKFENQLKTKVMKLENELEMaqqsaggrdtrfl 113
Cdd:PTZ00121 1565 KAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEE------------- 1631
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 114 RNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKqidsqKET 193
Cdd:PTZ00121 1632 KKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK-----AEE 1706
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 194 LLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKievQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQ 273
Cdd:PTZ00121 1707 LKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKK---KAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE 1783
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 274 -LKKENDHYQLQVQELTDLLKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEIIEYQQMlhnLREKLKNAQLDADKSNVMA 352
Cdd:PTZ00121 1784 eLDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNM---QLEEADAFEKHKFNKNNEN 1860
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2462534488 353 LQQGIQERDSQIKmlTEQVEQYTKEMEKNTCIIEDLKNELQRNKGASTLSQQTHMKIQSTLDILKEKTKEAERTAE 428
Cdd:PTZ00121 1861 GEDGNKEADFNKE--KDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDKDEYIKRDAEETRE 1934
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
967-1696 |
1.22e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 47.74 E-value: 1.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 967 KQYNELTAKYRDiLQKDNMLVQRTSNLEHLEceniSLKEQVESINKELEITKEKLHTIEQAWEQetkLGNESSMDKAKKS 1046
Cdd:TIGR02168 213 ERYKELKAELRE-LELALLVLRLEELREELE----ELQEELKEAEEELEELTAELQELEEKLEE---LRLEVSELEEEIE 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1047 ITNSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELETKFAELTKINLDAQKVEQMLRDELADSV 1126
Cdd:TIGR02168 285 ELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELE 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1127 SKAV-----SDADRQRILELEKNEMELKVEVSKLREISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQ------SD 1195
Cdd:TIGR02168 365 AELEelesrLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKelqaelEE 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1196 EKSLIAKLHQHNVSLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQALyyARLEGRNRAkhLRQTIQSlRRQFS 1275
Cdd:TIGR02168 445 LEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQ--ENLEGFSEG--VKALLKN-QSGLS 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1276 GALPLAQQ-----EKFSKTM------------IQLQNDKLKIMQEMKN-----------SQQEHRNMENKTLEMELKLKG 1327
Cdd:TIGR02168 520 GILGVLSElisvdEGYEAAIeaalggrlqavvVENLNAAKKAIAFLKQnelgrvtflplDSIKGTEIQGNDREILKNIEG 599
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1328 LEELISTL-KDTKGAQKVIN---WHMKI-------EELRLQELKLNRELVKD------------------------KEEI 1372
Cdd:TIGR02168 600 FLGVAKDLvKFDPKLRKALSyllGGVLVvddldnaLELAKKLRPGYRIVTLDgdlvrpggvitggsaktnssilerRREI 679
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1373 KYLNNIISEYERTISSLEEEIVQQNKFHEERQMAWDQ---REVDLERQLDIFDRQQNEILNAAQKFEEATGSIPDPSLPL 1449
Cdd:TIGR02168 680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQlrkELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEL 759
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1450 PNQLEIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAER-EKLIAELGRKEME 1528
Cdd:TIGR02168 760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERlESLERRIAATERR 839
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1529 pkshhtLKIAHQTIANMQARLNQKEEVLKKYQRLLEKAREEQREIVK---KHEEDLHILHHRLElQADSSLNKFKQtawd 1605
Cdd:TIGR02168 840 ------LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNeraSLEEALALLRSELE-ELSEELRELES---- 908
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1606 lmkqsptpvptnkhfiRLAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQRE-ITELKVKEFENIkLQLQENHEDEVKKVK 1684
Cdd:TIGR02168 909 ----------------KRSELRRELEELREKLAQLELRLEGLEVRIDNLQErLSEEYSLTLEEA-EALENKIEDDEEEAR 971
|
810
....*....|..
gi 2462534488 1685 AEVEDLKYLLDQ 1696
Cdd:TIGR02168 972 RRLKRLENKIKE 983
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1147-1957 |
1.27e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 47.76 E-value: 1.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1147 ELKVEVSKLREISDIARRQVEILNAQQQSRDKEVESL---RMQLLDYQAQSDEKS------LIAKLHQHNVSLQLSEATA 1217
Cdd:TIGR02169 167 EFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLrreREKAERYQALLKEKReyegyeLLKEKEALERQKEAIERQL 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1218 LGKLESITSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHLRQTIQSLRRQFSGALplAQQEKFSKTMIQLQNDK 1297
Cdd:TIGR02169 247 ASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLE--RSIAEKERELEDAEERL 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1298 LKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDTKGAQKVinwhmKIEELRLQELKLNRELVKDKEEIKYLNN 1377
Cdd:TIGR02169 325 AKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRA-----ELEEVDKEFAETRDELKDYREKLEKLKR 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1378 IISEYERTISSLEEEIVQqnkfheeRQMAWDQREVDLERQLDIFDRQQNEILNAAQKFEEATGSIPDPSLPLpNQLEIAL 1457
Cdd:TIGR02169 400 EINELKRELDRLQEELQR-------LSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADL-SKYEQEL 471
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1458 RKIKENIRIILETRatcKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAereKLIAELGRKEMEpkshHTLKI 1537
Cdd:TIGR02169 472 YDLKEEYDRVEKEL---SKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVH---GTVAQLGSVGER----YATAI 541
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1538 AHQTIANMQARLNQKEEVLKKYQRLLeKAREEQREI------VKKHEEDLHILHhrlelqadssLNKFKQTAWDLMKQSP 1611
Cdd:TIGR02169 542 EVAAGNRLNNVVVEDDAVAKEAIELL-KRRKAGRATflplnkMRDERRDLSILS----------EDGVIGFAVDLVEFDP 610
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1612 TPVPTNKHFIRlaemEQTVAEQDDSLSSLLVKLKKVSQD---LERQREITELKVKEFENIKLQLQEnhEDEVKKVKAEVE 1688
Cdd:TIGR02169 611 KYEPAFKYVFG----DTLVVEDIEAARRLMGKYRMVTLEgelFEKSGAMTGGSRAPRGGILFSRSE--PAELQRLRERLE 684
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1689 DLKYLLDQSQKESQCLKSELQAQKEANSRAP--TTTMRNLVERL-------KSQLALKEKQQKALSRALLELRAEMTAAA 1759
Cdd:TIGR02169 685 GLKRELSSLQSELRRIENRLDELSQELSDASrkIGEIEKEIEQLeqeeeklKERLEELEEDLSSLEQEIENVKSELKELE 764
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1760 EERiisATSQKEAHLNVQQIVDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILRE 1839
Cdd:TIGR02169 765 ARI---EELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQ 841
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1840 KEEIDQENDELKRQIkrltsglqgkpltDNKQSLIEELQRKVKKLENQLEgkveevDLKPMKEKNAKEELIRWEEGKKWQ 1919
Cdd:TIGR02169 842 RIDLKEQIKSIEKEI-------------ENLNGKKEELEEELEELEAALR------DLESRLGDLKKERDELEAQLRELE 902
|
810 820 830
....*....|....*....|....*....|....*...
gi 2462534488 1920 AKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKEK 1957
Cdd:TIGR02169 903 RKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPK 940
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
788-1525 |
1.64e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 47.36 E-value: 1.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 788 LQELENKEKKLKNLEDSLEDYNRKFAVIRHQ--QSLLYKEYLSEKET-----WKTESKTIKEEKRKLEDQVQQDAIKVKE 860
Cdd:TIGR02168 178 ERKLERTRENLDRLEDILNELERQLKSLERQaeKAERYKELKAELRElelalLVLRLEELREELEELQEELKEAEEELEE 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 861 YNNLLNALQMDSDEMKKILAENSRKITVLQvneKSLIRQYTTLVELERQLRKENEKQKNeLLSMEAEVCEKIGCLQRFKE 940
Cdd:TIGR02168 258 LTAELQELEEKLEELRLEVSELEEEIEELQ---KELYALANEISRLEQQKQILRERLAN-LERQLEELEAQLEELESKLD 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 941 MAIFKIAALQKVVDnsVSLSELELANKQYNELTAKYRDILQKdnmLVQRTSNLEHLECENISLKEQVESINKELEITKEK 1020
Cdd:TIGR02168 334 ELAEELAELEEKLE--ELKEELESLEAELEELEAELEELESR---LEELEEQLETLRSKVAQLELQIASLNNEIERLEAR 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1021 LHTIEQAWE--QETKLGNESSMDKAKKSITNSDIVSISKKITMLEMKELNERQRAEHCQKMYEHLRTSLKQME------- 1091
Cdd:TIGR02168 409 LERLEDRRErlQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAErelaqlq 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1092 ------ERNFELETKFAELTKINLDAQKVEQMLRDELADSVS------KAVSDADRQRILELE-KNEMELKVEVSKLRE- 1157
Cdd:TIGR02168 489 arldslERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISvdegyeAAIEAALGGRLQAVVvENLNAAKKAIAFLKQn 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1158 ---------ISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSdEKSLIAKLHQHNVSLQLSEATALGK-------- 1220
Cdd:TIGR02168 569 elgrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKL-RKALSYLLGGVLVVDDLDNALELAKklrpgyri 647
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1221 -------------------------------LESITSKLQKMEAYNLRLEQKLDEKEQALYyarlEGRNRAKHLRQTIQS 1269
Cdd:TIGR02168 648 vtldgdlvrpggvitggsaktnssilerrreIEELEEKIEELEEKIAELEKALAELRKELE----ELEEELEQLRKELEE 723
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1270 LRRQFSGALP-----LAQQEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDTKGAQKV 1344
Cdd:TIGR02168 724 LSRQISALRKdlarlEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1345 I--NWHMKIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQLDIFD 1422
Cdd:TIGR02168 804 AldELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1423 RQQNEILNAAQKFEEATGSIpdpslplpNQLEIALRKIKENIRIILETRATCKSLEEKLKEKESAL--RLAEQNILSRDK 1500
Cdd:TIGR02168 884 SLEEALALLRSELEELSEEL--------RELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLqeRLSEEYSLTLEE 955
|
810 820
....*....|....*....|....*
gi 2462534488 1501 VINELRLRLPATAEREKLIAELGRK 1525
Cdd:TIGR02168 956 AEALENKIEDDEEEARRRLKRLENK 980
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1453-1958 |
1.84e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 46.98 E-value: 1.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1453 LEIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPAT-AEREKLIAELGRKEMEPKS 1531
Cdd:PRK03918 160 YENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELrEELEKLEKEVKELEELKEE 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1532 HHTLKIAHQTIANMQARLNQKEEVLKKYQRLLEKAREEQREIVKKHEEdlhilhHRLELQADSSLNKFKqtawdlmkqsp 1611
Cdd:PRK03918 240 IEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKE------LKEKAEEYIKLSEFY----------- 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1612 tpvptNKHFIRLAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREITElKVKEFENIKLQLQENHE--DEVKKVKAEVED 1689
Cdd:PRK03918 303 -----EEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKK-KLKELEKRLEELEERHElyEEAKAKKEELER 376
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1690 LKYLLDQSQKESqcLKSELQAQKEANsraptTTMRNLVERLKSQLALKEKQQKALSRALLELR-AEMTAAAEERIISATS 1768
Cdd:PRK03918 377 LKKRLTGLTPEK--LEKELEELEKAK-----EEIEEEISKITARIGELKKEIKELKKAIEELKkAKGKCPVCGRELTEEH 449
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1769 QKEahlnvqqIVDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDN--------LNDLNNELQKKQKAYN-----K 1835
Cdd:PRK03918 450 RKE-------LLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKEseliklkeLAEQLKELEEKLKKYNleeleK 522
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1836 ILREKEEIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQRKVKKLENQLEGKVEEVDLKPMKE------------- 1902
Cdd:PRK03918 523 KAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEEleerlkelepfyn 602
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2462534488 1903 -----KNAKEEL-IRWEEGKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKEKL 1958
Cdd:PRK03918 603 eylelKDAEKELeREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEEL 664
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1622-1947 |
1.86e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 46.98 E-value: 1.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1622 RLAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQENHEDEvKKVKAEVEDLKYLLDQSQKES 1701
Cdd:TIGR02169 675 ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEE-EKLKERLEELEEDLSSLEQEI 753
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1702 QCLKSELQ--AQKEANSRAPTTTMRNLVERLKSQLALKEKQQK-ALSRALLELRAEMTAAAE--ERIISATSQKEAHLN- 1775
Cdd:TIGR02169 754 ENVKSELKelEARIEELEEDLHKLEEALNDLEARLSHSRIPEIqAELSKLEEEVSRIEARLReiEQKLNRLTLEKEYLEk 833
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1776 -----VQQIVDRHTR--ELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQEND 1848
Cdd:TIGR02169 834 eiqelQEQRIDLKEQikSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIE 913
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1849 ELKRQIKRLTSGLQG-----KPLTDNKQSLIEE---------LQRKVKKLENQLEgKVEEVDLKPMKEknakeelirWEE 1914
Cdd:TIGR02169 914 KKRKRLSELKAKLEAleeelSEIEDPKGEDEEIpeeelsledVQAELQRVEEEIR-ALEPVNMLAIQE---------YEE 983
|
330 340 350
....*....|....*....|....*....|...
gi 2462534488 1915 GKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLK 1947
Cdd:TIGR02169 984 VLKRLDELKEKRAKLEEERKAILERIEEYEKKK 1016
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1063-1854 |
2.03e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 46.89 E-value: 2.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1063 EMKELNERQRAEHCQKMYEHLRTSLKQMEERNFELETKFAELTKINLDAQKVEQMLRDELADSVSKAVSDADRQRILELE 1142
Cdd:pfam02463 202 LKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEK 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1143 KNEMELKVEVSKLREIS----DIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKSLIAKLHQHNVSLQLSEATAL 1218
Cdd:pfam02463 282 KLQEEELKLLAKEEEELkselLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEEL 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1219 GKLESITSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAKHLRQTIQSLRRQFSGALPLAQQEKFSKTMIQL--QND 1296
Cdd:pfam02463 362 EKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEesIEL 441
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1297 KLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDTKGAQKVINWHMKIEELRLQELKLNRELVKDKEEIKYLN 1376
Cdd:pfam02463 442 KQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVG 521
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1377 NIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQLDIFDRQQNEILNAAQKFEEATGSIPDPSLPL-PNQLEI 1455
Cdd:pfam02463 522 GRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIaVLEIDP 601
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1456 ALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAEREKLIAELGRKEMEPKSHHTL 1535
Cdd:pfam02463 602 ILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQEL 681
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1536 KIAHQTIANMQARLNQKEEVLKKYQRLLEKAREEQREIVKKHEEDLHILHHRLELQADSSLNKFKQTAWDLMKQSPTPVP 1615
Cdd:pfam02463 682 QEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEE 761
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1616 TNKHFIRLAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVEDLKYLLD 1695
Cdd:pfam02463 762 KEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALE 841
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1696 QSQKESQCLKSELQAQKEANSRAPTTTMRNLVERLKSQLALKEKQQKALSRA-------LLELRAEMTAAAEERIISATS 1768
Cdd:pfam02463 842 LKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEkekeekkELEEESQKLNLLEEKENEIEE 921
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1769 QKEAHLNVQQIVDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNN----ELQKKQKAYNKILREKEEID 1844
Cdd:pfam02463 922 RIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLmaieEFEEKEERYNKDELEKERLE 1001
|
810
....*....|
gi 2462534488 1845 QENDELKRQI 1854
Cdd:pfam02463 1002 EEKKKLIRAI 1011
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
1678-1887 |
2.29e-04 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 46.83 E-value: 2.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1678 DEVKKVKAEVEDLKYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRNL-VERLKSQLALKEKQQKALSRALLELRAEMT 1756
Cdd:PRK11281 73 DKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLsLRQLESRLAQTLDQLQNAQNDLAEYNSQLV 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1757 AA--AEERIISATSQkeahlNVQQivdrhTRELKTQVEDLNENLLKLKEALKTSKNRENSLTdnlnDLNNELQKKQKAYN 1834
Cdd:PRK11281 153 SLqtQPERAQAALYA-----NSQR-----LQQIRNLLKGGKVGGKALRPSQRVLLQAEQALL----NAQNDLQRKSLEGN 218
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2462534488 1835 KILREKEEidQENDELKRQIKRLTSGLQgkpltdNKQSLI-----EELQRKVKKLENQ 1887
Cdd:PRK11281 219 TQLQDLLQ--KQRDYLTARIQRLEHQLQ------LLQEAInskrlTLSEKTVQEAQSQ 268
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
153-734 |
2.35e-04 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 46.74 E-value: 2.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 153 EEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLLSRRgedsdyrsqlskknyeliqylDEIQTLTEAneki 232
Cdd:pfam10174 112 ELTEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQKQTLGARD---------------------ESIKKLLEM---- 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 233 eVQNQEMRKNLEESVQEMEKMTDEYnrmKAIVHQTDNVIDQLKKENDHyqlqvqeLTDLLKSKNEeddpiMVAVNAKVEE 312
Cdd:pfam10174 167 -LQSKGLPKKSGEEDWERTRRIAEA---EMQLGHLEVLLDQKEKENIH-------LREELHRRNQ-----LQPDPAKTKA 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 313 WKLILSSKDDEIIEYQQMLHNLREklknaQLDADKSNVMAlqqGIQERDSQIKMLtEQVEQYTKEMEKNtciIEDLKNEL 392
Cdd:pfam10174 231 LQTVIEMKDTKISSLERNIRDLED-----EVQMLKTNGLL---HTEDREEEIKQM-EVYKSHSKFMKNK---IDQLKQEL 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 393 QRnKGASTLSQQTHMKIQST--------LDILKEKTKEAERTAEL--AEADA-----REKDKELVEALKRLKDYESGVYG 457
Cdd:pfam10174 299 SK-KESELLALQTKLETLTNqnsdckqhIEVLKESLTAKEQRAAIlqTEVDAlrlrlEEKESFLNKKTKQLQDLTEEKST 377
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 458 LEDavvEIKNCKNQIKIRDREIEILTKEINKLELKISDFLDENEALRERV-GLEPKTMIDLTEF-----------RNSKH 525
Cdd:pfam10174 378 LAG---EIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVkSLQTDSSNTDTALttleealsekeRIIER 454
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 526 LKQQQYRaENQILLKEIESLEEERLDLKKKIRQMAQERGKRSA--------TSGLTTEDLNLTENISQGDRISERKLD-- 595
Cdd:pfam10174 455 LKEQRER-EDRERLEELESLKKENKDLKEKVSALQPELTEKESslidlkehASSLASSGLKKDSKLKSLEIAVEQKKEec 533
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 596 ------LLSLKNMSEAQSKNEFLSRELIEKERDLERSRTVIAKFQNKLKELVEENKQLEEGMKEILQAIKEMQKDPDVKG 669
Cdd:pfam10174 534 sklenqLKKAHNAEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELESLTLRQM 613
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462534488 670 GETSLIIPSLERLVNAIESKNAEGIFDASL--------HLKAQVDQLTGRNEELRQELRESRKEAINYSQQLA 734
Cdd:pfam10174 614 KEQNKKVANIKHGQQEMKKKGAQLLEEARRrednladnSQQLQLEELMGALEKTRQELDATKARLSSTQQSLA 686
|
|
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
1645-1961 |
3.33e-04 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 45.90 E-value: 3.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1645 KKVSQDLERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQS----QKESQCLKSELQAQKEANSRAPT 1720
Cdd:pfam09731 121 KSEQEKEKALEEVLKEAISKAESATAVAKEAKDDAIQAVKAHTDSLKEASDTAeisrEKATDSALQKAEALAEKLKEVIN 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1721 TTMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVdrhtRELKTQVEDLNENLlk 1800
Cdd:pfam09731 201 LAKQSEEEAAPPLLDAAPETPPKLPEHLDNVEEKVEKAQSLAKLVDQYKELVASERIVFQ----QELVSIFPDIIPVL-- 274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1801 lKEALKTSKNRENSLTD----NLNDLNNELQKKQKAYNKilREKEEIDQENDELKRQIKRLTSGLQGKPLTDNKQsLIEE 1876
Cdd:pfam09731 275 -KEDNLLSNDDLNSLIAhahrEIDQLSKKLAELKKREEK--HIERALEKQKEELDKLAEELSARLEEVRAADEAQ-LRLE 350
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1877 LQRKV--------KKLENQLEGKVEEVDLKPMKEKNAKEELIRWEEGKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLKD 1948
Cdd:pfam09731 351 FEREReeiresyeEKLRTELERQAEAHEEHLKDVLVEQEIELQREFLQDIKEKVEEERAGRLLKLNELLANLKGLEKATS 430
|
330
....*....|...
gi 2462534488 1949 LFAKADKEKLTLQ 1961
Cdd:pfam09731 431 SHSEVEDENRKAQ 443
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1623-1979 |
3.38e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 46.21 E-value: 3.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1623 LAEMEQTVAEQD---DSLSSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQSQK 1699
Cdd:TIGR02169 179 LEEVEENIERLDliiDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTE 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1700 ESQCLKSELQAQKEansrapttTMRNLVERLKsqlALKEKQQKALSRALLELRAEMtAAAEERIISATSQKEAHLNVQQI 1779
Cdd:TIGR02169 259 EISELEKRLEEIEQ--------LLEELNKKIK---DLGEEEQLRVKEKIGELEAEI-ASLERSIAEKERELEDAEERLAK 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1780 VDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIkrlts 1859
Cdd:TIGR02169 327 LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI----- 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1860 glqgKPLTDNKQSLIEELQRKVKKLEnQLEGKVEEVDLKPMKEKNAKEELIrwEEGKKWQAKIEGIRNKLKEKEGEVFTL 1939
Cdd:TIGR02169 402 ----NELKRELDRLQEELQRLSEELA-DLNAAIAGIEAKINELEEEKEDKA--LEIKKQEWKLEQLAADLSKYEQELYDL 474
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 2462534488 1940 TKQLNTLKDLFAKADKEkltLQRKLKTTGMTVDQVLGIRA 1979
Cdd:TIGR02169 475 KEEYDRVEKELSKLQRE---LAEAEAQARASEERVRGGRA 511
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
36-277 |
4.94e-04 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 45.44 E-value: 4.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 36 EVNELKSEKQENVIHLFRITQSLMKMKAQEVELALEEVEKAGEEQAKFENQLKTKVMKLENELEMAQQSAGGR-----DT 110
Cdd:TIGR02169 252 ELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLakleaEI 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 111 RFLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQ 190
Cdd:TIGR02169 332 DKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRL 411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 191 KETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNV 270
Cdd:TIGR02169 412 QEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRE 491
|
....*..
gi 2462534488 271 IDQLKKE 277
Cdd:TIGR02169 492 LAEAEAQ 498
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
1373-1891 |
5.21e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 45.49 E-value: 5.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1373 KYLNNIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQLDIFDRQQNEILNAAQKfeeatgsipdpslplPNQ 1452
Cdd:pfam15921 74 EHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRR---------------ESQ 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1453 LEIALRKIKENIRIILETRATCKslEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAE-------REKLIAELGRK 1525
Cdd:pfam15921 139 SQEDLRNQLQNTVHELEAAKCLK--EDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEasgkkiyEHDSMSTMHFR 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1526 EMEPKSHHTLKIAHQTIANMQARLNQKEEVLK--------KYQRLLEKAREEQREIVKKHEEDLHILHHRLElQADSSLN 1597
Cdd:pfam15921 217 SLGSAISKILRELDTEISYLKGRIFPVEDQLEalksesqnKIELLLQQHQDRIEQLISEHEVEITGLTEKAS-SARSQAN 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1598 KFKQTAWDLMKQSPTpvpTNKHFIR-LAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQE-- 1674
Cdd:pfam15921 296 SIQSQLEIIQEQARN---QNSMYMRqLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQes 372
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1675 -NHEDEVKKVkaevedlkyLLDQSQKEsqclkSELQAQKEANSRAPTTTMRN--LVERLKSQLALKEKQQKALSRALLEL 1751
Cdd:pfam15921 373 gNLDDQLQKL---------LADLHKRE-----KELSLEKEQNKRLWDRDTGNsiTIDHLRRELDDRNMEVQRLEALLKAM 438
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1752 RAEMTAAAEERIISATSQKEAHLNVQQivdrhtreLKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQK 1831
Cdd:pfam15921 439 KSECQGQMERQMAAIQGKNESLEKVSS--------LTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKER 510
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1832 AynkilrekeeIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQRKVKKLENQLEGK 1891
Cdd:pfam15921 511 A----------IEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEK 560
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
415-1255 |
5.43e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 45.35 E-value: 5.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 415 ILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESgvygLEDAVVEIKNCKNQIKIRDREIEILTKEINKLELKIS 494
Cdd:pfam02463 164 GSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKL----KEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERI 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 495 DFLDENEALRERVGL----EPKTMIDLTEFRNSKHLKQQQYRAENQILLKEIESLEEERLDLKKKIRQMAQERGKRSATS 570
Cdd:pfam02463 240 DLLQELLRDEQEEIEsskqEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKES 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 571 GLTTEDLNLTENISQGDRISERKLDLLSLKNMSEAQSKNEFLSRELIEKERDLERSRTVIAKFQNKLKELVEENKQLEEG 650
Cdd:pfam02463 320 EKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELEL 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 651 MKEILQAIKEMQKDPDVKGGETSLIIPSLERLVNAIESKNAEGIFDASLHLKAQVDQLTGRNEELRQELRESRKEAINYS 730
Cdd:pfam02463 400 KSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQL 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 731 QQLAKANLKIDHLEKETSLLRQSEGSNVVFKGIDLPDGIAPSSASIINSQNEYLIHLLQELEnkekKLKNLEDSLEDYNR 810
Cdd:pfam02463 480 VKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENY----KVAISTAVIVEVSA 555
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 811 KFAVIRHQQSLLYKEYLSEKETWKTESKTIKEEKRKLEDQVQQDAIKVKEYNNLLNALQMDSDEMKKILAENSRKITVLQ 890
Cdd:pfam02463 556 TADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELT 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 891 VNEKSLIRQYTTLVELERQLRKENEKQK-NELLSMEAEVCEKIGCLQRFKEMAIFKIAALQKVVDNSVSLSELELANKQY 969
Cdd:pfam02463 636 KLKESAKAKESGLRKGVSLEEGLAEKSEvKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKL 715
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 970 NELTAKYRDILQKDNMLVQRTSNLEHLECENISLKEQVESINKELEITKEKLHTIEQAWEQETKLGNESSMDKAKKSITN 1049
Cdd:pfam02463 716 KLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEK 795
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1050 SDIVSISKKITMLEMKELNERQRA-----EHCQKMYEHLRTSLKQMEERNFELETKFAELTKINLDAQKVEQMLRDELAD 1124
Cdd:pfam02463 796 LKAQEEELRALEEELKEEAELLEEeqlliEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLK 875
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1125 SVSKAVSDADRQRILELEKNEMELKVEVSKLREISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKSLIAKLH 1204
Cdd:pfam02463 876 EEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNK 955
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|.
gi 2462534488 1205 QHNVSLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQALYYARLE 1255
Cdd:pfam02463 956 EEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKK 1006
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1671-1863 |
5.63e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.75 E-value: 5.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1671 QLQENHEDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQAQKEANSRApTTTMRNL---VERLKSQLALKEKQQKALSRA 1747
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAL-ARRIRALeqeLAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1748 LLELR---AEMTAAAEER--------IISATSQKEAhLNVQQIVDRHTRELKTQVEDLNEN---LLKLKEALKTSKNREN 1813
Cdd:COG4942 99 LEAQKeelAELLRALYRLgrqpplalLLSPEDFLDA-VRRLQYLKYLAPARREQAEELRADlaeLAALRAELEAERAELE 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2462534488 1814 SLTDNLNDLNNELQKKQKAYNKIL----REKEEIDQENDELKRQIKRLTSGLQG 1863
Cdd:COG4942 178 ALLAELEEERAALEALKAERQKLLarleKELAELAAELAELQQEAEELEALIAR 231
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
970-1310 |
6.07e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 45.11 E-value: 6.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 970 NELTAKYRDILQKDNMLVQRTSNLEHLECENISLKEQVESINKELEiTKEKLHTIEQAWEQEtklgnessMDKakksitN 1049
Cdd:pfam17380 268 NEFLNQLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVE-RRRKLEEAEKARQAE--------MDR------Q 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1050 SDIVSISKKITMLEMKELnERQRAEHCQKMYEHLRtslkqMEERNFELEtKFAELTKINLDAQKVEQMLRDELADSVSKA 1129
Cdd:pfam17380 333 AAIYAEQERMAMEREREL-ERIRQEERKRELERIR-----QEEIAMEIS-RMRELERLQMERQQKNERVRQELEAARKVK 405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1130 VSDADRQRILELEKNEMEL------KVEVSKLREISDIARRQVEILNAQQQSRDKEVESLRMQlldyQAQSDEKSLIAKL 1203
Cdd:pfam17380 406 ILEEERQRKIQQQKVEMEQiraeqeEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQ----EEERKRKKLELEK 481
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1204 HQHNVSLQLSEATALGKLESITSKLQKMEAYNLR--LEQKLDEKEQALYYArlEGRNRAKHLRQTIQSL--RRQFSGALP 1279
Cdd:pfam17380 482 EKRDRKRAEEQRRKILEKELEERKQAMIEEERKRklLEKEMEERQKAIYEE--ERRREAEEERRKQQEMeeRRRIQEQMR 559
|
330 340 350
....*....|....*....|....*....|.
gi 2462534488 1280 LAQQEKFSKTMIQLQNDKLKIMQEMKNSQQE 1310
Cdd:pfam17380 560 KATEERSRLEAMEREREMMRQIVESEKARAE 590
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
106-373 |
1.18e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 44.29 E-value: 1.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 106 GGRDTRFLRNEICQLEKQLEQKDRELEDMEKELEK-EKKVNEQLALRNE------EAENENSKLRRENKRLKKKNEQLCQ 178
Cdd:TIGR02169 658 GSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSlQSELRRIENRLDElsqelsDASRKIGEIEKEIEQLEQEEEKLKE 737
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 179 DIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTL--TEANEKIEVQNQEMRKnLEESVQEMEKMTDE 256
Cdd:TIGR02169 738 RLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLeaRLSHSRIPEIQAELSK-LEEEVSRIEARLRE 816
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 257 YNRMKAIVHQTDNVIDQLKKEndhyqlqVQELTDLLKSKNEEddpimvaVNAKVEEWKLILSSKDDEIIEYQQMLHNLRE 336
Cdd:TIGR02169 817 IEQKLNRLTLEKEYLEKEIQE-------LQEQRIDLKEQIKS-------IEKEIENLNGKKEELEEELEELEAALRDLES 882
|
250 260 270
....*....|....*....|....*....|....*....
gi 2462534488 337 KLKNAQLDAD--KSNVMALQQGIQERDSQIKMLTEQVEQ 373
Cdd:TIGR02169 883 RLGDLKKERDelEAQLRELERKIEELEAQIEKKRKRLSE 921
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1662-2396 |
1.50e-03 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 43.98 E-value: 1.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1662 VKEFENIKLQLQENHEDEVKKVKAE--VEDLKYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRNLVERLKSQLALKEK 1739
Cdd:PTZ00121 1199 ARKAEAARKAEEERKAEEARKAEDAkkAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEAR 1278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1740 QQKALSRALLELRAEMTAAAEERIISATSQKEAHLNvqqivdRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNL 1819
Cdd:PTZ00121 1279 KADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEA------KKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEA 1352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1820 NDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQRK--VKKLENQLEGKVEEVDl 1897
Cdd:PTZ00121 1353 EAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAaaAKKKADEAKKKAEEKK- 1431
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1898 KPMKEKNAKEELIRWEEGKK---WQAKIEGIRNKLKE--KEGEVFTLTKQLNTLKDLFAKAD---------KEKLTLQRK 1963
Cdd:PTZ00121 1432 KADEAKKKAEEAKKADEAKKkaeEAKKAEEAKKKAEEakKADEAKKKAEEAKKADEAKKKAEeakkkadeaKKAAEAKKK 1511
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1964 LKTTGMTVDQVLGIRALESEKELEELKKRNLDLENDILYMRAHQALPRDSVVEDLHLQNRYLQEKLHALEKQFSKDTYSK 2043
Cdd:PTZ00121 1512 ADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEE 1591
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2044 PSISGI----ESDDHCQREQELQKENLKLSSENIElkfQLEQANKDLPRLKNQVRDLKEMCEFLKKEKAEVQ-RKLGHVR 2118
Cdd:PTZ00121 1592 ARIEEVmklyEEEKKMKAEEAKKAEEAKIKAEELK---KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKiKAAEEAK 1668
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2119 GAELEKLKAhlgHQLSMHYESKTKGTEKIIAEN------ERLRKELKKETDAAEKLRIAKNNLEILNEKMTVQLEETGKR 2192
Cdd:PTZ00121 1669 KAEEDKKKA---EEAKKAEEDEKKAAEALKKEAeeakkaEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKK 1745
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2193 LQfaESRGPQLEGADSKSWKSIVVTRMYETKlKELETDIAKKNQSITDLKQLVKEATEREQKVNKYNeDLEQQIKILKHV 2272
Cdd:PTZ00121 1746 AE--EAKKDEEEKKKIAHLKKEEEKKAEEIR-KEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFAN-IIEGGKEGNLVI 1821
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2273 PEGAETEQGLKRElqVLRLANHQLDKEKAELIHQIEANKDQSGAESTIPDADQLKEKIKDLETQLKMSDLEKQhLKEEIK 2352
Cdd:PTZ00121 1822 NDSKEMEDSAIKE--VADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEK-IDKDDI 1898
|
730 740 750 760
....*....|....*....|....*....|....*....|....*
gi 2462534488 2353 KLKKELENFDPSFFEEIEDlKYNYKEEVKKNI-LLEEKVKKLSEQ 2396
Cdd:PTZ00121 1899 EREIPNNNMAGKNNDIIDD-KLDKDEYIKRDAeETREEIIKISKK 1942
|
|
| PRK03992 |
PRK03992 |
proteasome-activating nucleotidase; Provisional |
130-176 |
1.66e-03 |
|
proteasome-activating nucleotidase; Provisional
Pssm-ID: 179699 [Multi-domain] Cd Length: 389 Bit Score: 43.28 E-value: 1.66e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 2462534488 130 ELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQL 176
Cdd:PRK03992 2 RLEALEERNSELEEQIRQLELKLRDLEAENEKLERELERLKSELEKL 48
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1626-1846 |
1.71e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.85 E-value: 1.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1626 MEQTVAEQDDSLSSLLVKLKKVSQDLER-QREITELKVK-------EFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQS 1697
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEaEAALEEFRQKnglvdlsEEAKLLLQQLSELESQLAEARAELAEAEARLAAL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1698 QKEsqcLKSELQAQKEANSRAPTTTMRNLVERLKSQLALKEKQQKALSRALLELRAEMtAAAEERIISATSQKEAHLNVQ 1777
Cdd:COG3206 246 RAQ---LGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQI-AALRAQLQQEAQRILASLEAE 321
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2462534488 1778 QivdrhtRELKTQVEDLNENLLKLKEALKTSKNREnsltDNLNDLNNELQKKQKAYNKILREKEEIDQE 1846
Cdd:COG3206 322 L------EALQAREASLQAQLAQLEARLAELPELE----AELRRLEREVEVARELYESLLQRLEEARLA 380
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
1645-2345 |
1.84e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 43.80 E-value: 1.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1645 KKVSQDLERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQAQKEANSRaptttmr 1724
Cdd:TIGR00618 186 FAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKK------- 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1725 nlvERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNvQQIVDRHTrELKTQVEDLNENLLKLKEA 1804
Cdd:TIGR00618 259 ---QQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIE-QQAQRIHT-ELQSKMRSRAKLLMKRAAH 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1805 LKTSKNRENSlTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQRKVKKL 1884
Cdd:TIGR00618 334 VKQQSSIEEQ-RRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATI 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1885 ENQLEgkvEEVDLKPMKEKNAKEELIRWEEGKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKEKLTLQRKL 1964
Cdd:TIGR00618 413 DTRTS---AFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKK 489
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1965 KTTGMTVDQVLGIRALESEKELEELKKRNLDLENDILYMRAHQALPR----DSVVEDLHLQNRYLQEKLHALEKQFS--K 2038
Cdd:TIGR00618 490 AVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTyaqlETSEEDVYHQLTSERKQRASLKEQMQeiQ 569
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2039 DTYSKPSISGIESDDHCQREQELQKENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKEMCEFLKKEKAEVQRKLGHVR 2118
Cdd:TIGR00618 570 QSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALH 649
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2119 GAELEKLKAHLGHQLSMHYESKTKGTEKIIAENERLRKELKKETDAAEKLRIAKNNLEILNEKMTVQLEETGKRLQFAES 2198
Cdd:TIGR00618 650 ALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSS 729
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2199 RGPQLEGADSKSWKSI-VVTRMYETKLKELETDIAKKNQSITDLKQLVKEATEREQKVNKYNEDLEQQIKILKHVPegAE 2277
Cdd:TIGR00618 730 LGSDLAAREDALNQSLkELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLE--AE 807
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2278 TEQGLKRELQVLRLANHQLDKEKAELIHQIEANKDQSGAESTI--PDADQLKEKIKDLETQLKMSDLEKQ 2345
Cdd:TIGR00618 808 IGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQllKYEECSKQLAQLTQEQAKIIQLSDK 877
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
703-1581 |
2.30e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 43.51 E-value: 2.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 703 AQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKETSLLRqsegsnvvfkgidlpdgiapssaSIINSQNE 782
Cdd:TIGR02168 225 LELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELR-----------------------LEVSELEE 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 783 YLIHLLQELENKEKKLKNLEDSLEDYNRKFAVIRHQQsllyKEYLSEKETWKTESKTIKEEKRKLEDQVQQDAIKVKEYN 862
Cdd:TIGR02168 282 EIEELQKELYALANEISRLEQQKQILRERLANLERQL----EELEAQLEELESKLDELAEELAELEEKLEELKEELESLE 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 863 NLLNALQMDSDEMKKILAEnsrkitvlqvneksLIRQYTTLVELERQLRKENEKQKNELLSMEAEvcekigclqrfkema 942
Cdd:TIGR02168 358 AELEELEAELEELESRLEE--------------LEEQLETLRSKVAQLELQIASLNNEIERLEAR--------------- 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 943 ifkIAALQKVVDNSVSLSELELANKQYNELTAKYRDILQKDNMLVQRTSNLEHLECENISLKEQVESINKELEITKEKLH 1022
Cdd:TIGR02168 409 ---LERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA 485
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1023 TIEQAWEQ-ETKLGNESSMDKAKKSITN------------SDIVSISKK------------ITMLEMKELNERQRAEHCQ 1077
Cdd:TIGR02168 486 QLQARLDSlERLQENLEGFSEGVKALLKnqsglsgilgvlSELISVDEGyeaaieaalggrLQAVVVENLNAAKKAIAFL 565
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1078 KMYEHLRTSlkqmeernfeletkFAELTKINLDAQKVEQMLRDELADSVskavsdadRQRILELEKNEMELKVEVSKLRE 1157
Cdd:TIGR02168 566 KQNELGRVT--------------FLPLDSIKGTEIQGNDREILKNIEGF--------LGVAKDLVKFDPKLRKALSYLLG 623
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1158 ISDIARRqveILNAQQQSRDKEVESLRMQLLDYQAQSDekSLIAKLHQHNVSLQLSEATALGKLEsitSKLQKMEAYNLR 1237
Cdd:TIGR02168 624 GVLVVDD---LDNALELAKKLRPGYRIVTLDGDLVRPG--GVITGGSAKTNSSILERRREIEELE---EKIEELEEKIAE 695
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1238 LEQKLDEKEQALYyarlEGRNRAKHLRQTIQSLRRQFSGALplaqqekfsktmIQLQNDKLKIMQEMKNSQQEHRNMENK 1317
Cdd:TIGR02168 696 LEKALAELRKELE----ELEEELEQLRKELEELSRQISALR------------KDLARLEAEVEQLEERIAQLSKELTEL 759
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1318 TLEMELKLKGLEELISTLKDTKGaqkvinwhmKIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIVQqn 1397
Cdd:TIGR02168 760 EAEIEELEERLEEAEEELAEAEA---------EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLES-- 828
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1398 kfHEERQMAWDQREVDLERQLDifdrqqneilNAAQKFEEATGSIpdpslplpNQLEIALRKIKENIRIILETRAtckSL 1477
Cdd:TIGR02168 829 --LERRIAATERRLEDLEEQIE----------ELSEDIESLAAEI--------EELEELIEELESELEALLNERA---SL 885
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1478 EEKLKEKESALRLAEQNILSRDKVINELRlrlpatAEREKLIAELGRKEMEpkshhtLKIAHQTIANMQARLNQK----E 1553
Cdd:TIGR02168 886 EEALALLRSELEELSEELRELESKRSELR------RELEELREKLAQLELR------LEGLEVRIDNLQERLSEEysltL 953
|
890 900
....*....|....*....|....*...
gi 2462534488 1554 EVLKKYQRLLEKAREEQREIVKKHEEDL 1581
Cdd:TIGR02168 954 EEAEALENKIEDDEEEARRRLKRLENKI 981
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
35-200 |
2.91e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 42.92 E-value: 2.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 35 VEVNELKSEkqenVIHLFRITQSLMKMKAQEVELALEEVEKAGEEQAKFENQLKTKVMKLENELEMaqqsaggrdtrfLR 114
Cdd:COG2433 363 VDRDEVKAR----VIRGLSIEEALEELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVER------------LE 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 115 NEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLALRNEEAenenSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETL 194
Cdd:COG2433 427 AEVEELEAELEEKDERIERLERELSEARSEERREIRKDREI----SRLDREIERLERELEEERERIEELKRKLERLKELW 502
|
....*..
gi 2462534488 195 -LSRRGE 200
Cdd:COG2433 503 kLEHSGE 509
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1756-1964 |
3.32e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 42.51 E-value: 3.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1756 TAAAEERIISATSQKEAHLNVQQIVDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNK 1835
Cdd:COG3883 11 PAFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGE 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1836 ILREKEEIDQENDELK-----RQIKRLTSGLQG-KPLTDNKQSLIEELQRKVKKLENQLEGKVEEVDlkpmKEKNAKEEL 1909
Cdd:COG3883 91 RARALYRSGGSVSYLDvllgsESFSDFLDRLSAlSKIADADADLLEELKADKAELEAKKAELEAKLA----ELEALKAEL 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2462534488 1910 irweegkkwQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKEKLTLQRKL 1964
Cdd:COG3883 167 ---------EAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAA 212
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
1446-1895 |
3.33e-03 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 42.73 E-value: 3.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1446 SLPLPNQLEIALRKIKEN-----IRIILETRATCKSLEEKlkekesalRLAEQNILSRDKVINELrlrlpataerEKLIA 1520
Cdd:PRK10929 21 TAPDEKQITQELEQAKAAktpaqAEIVEALQSALNWLEER--------KGSLERAKQYQQVIDNF----------PKLSA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1521 ELgRKEMEPKSHHTLKI-AHQTIANmqarLNQkeEVLKKYQRLLEKAREEQreivkkHEEDlhilhhRLELQADsSLNKF 1599
Cdd:PRK10929 83 EL-RQQLNNERDEPRSVpPNMSTDA----LEQ--EILQVSSQLLEKSRQAQ------QEQD------RAREISD-SLSQL 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1600 KQTAWDLMKQsptpvptnkhfirLAEMEQTVAEQDDSLSSLlvklkKVSQDLERQREITELKVKEFENIKLQLQENHEDE 1679
Cdd:PRK10929 143 PQQQTEARRQ-------------LNEIERRLQTLGTPNTPL-----AQAQLTALQAESAALKALVDELELAQLSANNRQE 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1680 VKKVKAEVEDLKYllDQSQKESQCLKSEL--QAQKEANSRAPTTTM-----RNLVERLKSQLalkeKQQKALSRALLELR 1752
Cdd:PRK10929 205 LARLRSELAKKRS--QQLDAYLQALRNQLnsQRQREAERALESTELlaeqsGDLPKSIVAQF----KINRELSQALNQQA 278
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1753 AEMTA-AAEERiiSATSQKeahLNVQQIVDRhTRE--------------LKTQVEDLNE---------NLLKLK-EALKT 1807
Cdd:PRK10929 279 QRMDLiASQQR--QAASQT---LQVRQALNT-LREqsqwlgvsnalgeaLRAQVARLPEmpkpqqldtEMAQLRvQRLRY 352
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1808 SK--NRENSLTDNLNDLNNELQKKQkayNKILrekeeidqeNDELKRQIKRLTSGLQGkpltdnKQSLIEELQrKVKKLE 1885
Cdd:PRK10929 353 EDllNKQPQLRQIRQADGQPLTAEQ---NRIL---------DAQLRTQRELLNSLLSG------GDTLILELT-KLKVAN 413
|
490
....*....|
gi 2462534488 1886 NQLEGKVEEV 1895
Cdd:PRK10929 414 SQLEDALKEV 423
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
416-640 |
3.33e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.70 E-value: 3.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 416 LKEKTKEAERTAELAEADAREKDKELVEALKRLKDY--ESGVYGLEDavveikncknQIKIRDREIEILTKEINKLELKI 493
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEFrqKNGLVDLSE----------EAKLLLQQLSELESQLAEARAEL 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 494 SDFLDENEALRERVGLEPKTMIDLTEFRNSKHLKQQQYRAENQI--LLK-------EIESLEEERLDLKKKIRQMAQE-- 562
Cdd:COG3206 236 AEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELaeLSArytpnhpDVIALRAQIAALRAQLQQEAQRil 315
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462534488 563 RGKRSATSGLTTEDLNLTENISQgdrISERkldllsLKNMSEAQskneflsRELIEKERDLERSRTVIAKFQNKLKEL 640
Cdd:COG3206 316 ASLEAELEALQAREASLQAQLAQ---LEAR------LAELPELE-------AELRRLEREVEVARELYESLLQRLEEA 377
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
1628-1896 |
3.37e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 42.69 E-value: 3.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1628 QTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKefeniklqLQENHEDEVKKV-KAEVEDLKYLLDQSQKESQCLKS 1706
Cdd:PHA02562 163 SVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIK--------TYNKNIEEQRKKnGENIARKQNKYDELVEEAKTIKA 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1707 ELqaqkeansraptttmrnlvERLKSQLALKEKQQKALSRALLELRAEMTAAAEERiisATSQKEAHLN---------VQ 1777
Cdd:PHA02562 235 EI-------------------EELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKI---EQFQKVIKMYekggvcptcTQ 292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1778 QIVDrhTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRL 1857
Cdd:PHA02562 293 QISE--GPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEEL 370
|
250 260 270
....*....|....*....|....*....|....*....
gi 2462534488 1858 TSGlqgkplTDNKQSLIEELQRKVKKLENQLEGKVEEVD 1896
Cdd:PHA02562 371 QAE------FVDNAEELAKLQDELDKIVKTKSELVKEKY 403
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
149-394 |
4.19e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.06 E-value: 4.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 149 ALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNyeliqylDEIQTLTEA 228
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALE-------AELAELEKE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 229 NEKIEVQNQEMRKNLEESVQEMEKMtDEYNRMKAIVHQTDnvidqlkkendhyQLQVQELTDLLKSKNEEDDPIMVAVNA 308
Cdd:COG4942 92 IAELRAELEAQKEELAELLRALYRL-GRQPPLALLLSPED-------------FLDAVRRLQYLKYLAPARREQAEELRA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 309 KVEEwkliLSSKDDEIIEYQQMLHNLREKLKNAQLdadksnvmALQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDL 388
Cdd:COG4942 158 DLAE----LAALRAELEAERAELEALLAELEEERA--------ALEALKAERQKLLARLEKELAELAAELAELQQEAEEL 225
|
....*.
gi 2462534488 389 KNELQR 394
Cdd:COG4942 226 EALIAR 231
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1292-1762 |
4.35e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 42.36 E-value: 4.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1292 QLQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKdtkgaqkvinwhmKIEELRLQELKLNRELVKDKEE 1371
Cdd:PRK03918 242 ELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK-------------ELKEKAEEYIKLSEFYEEYLDE 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1372 IKYLNNIISEYERTISSLEEEIVQQNKfHEERQMAWDQREVDLERQLDIFDRQQNEILNAAQKFEEATGSipdpslplpn 1451
Cdd:PRK03918 309 LREIEKRLSRLEEEINGIEERIKELEE-KEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERL---------- 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1452 QLEIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAEREKLIAELGRKEMEPKS 1531
Cdd:PRK03918 378 KKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEY 457
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1532 HHTLKiahqTIANMQARLNQKEEVLKKYQRLLEKAREEQREIVKKHE--EDLHILHHRLElqaDSSLNKFKQTAWDLMKQ 1609
Cdd:PRK03918 458 TAELK----RIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKElaEQLKELEEKLK---KYNLEELEKKAEEYEKL 530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1610 SPTPVPTNKHFIRLAEMEQTVAEQDDSLSSLLVKLKKVSQDL-ERQREITELKVKEFENIKLQLQE------------NH 1676
Cdd:PRK03918 531 KEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELaELLKELEELGFESVEELEERLKElepfyneylelkDA 610
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1677 EDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQAQKE--------------ANSRAPTTTMRNLVERLKSQLALKEKQQK 1742
Cdd:PRK03918 611 EKELEREEKELKKLEEELDKAFEELAETEKRLEELRKeleelekkyseeeyEELREEYLELSRELAGLRAELEELEKRRE 690
|
490 500
....*....|....*....|
gi 2462534488 1743 ALSRALLELRAEMTAAAEER 1762
Cdd:PRK03918 691 EIKKTLEKLKEELEEREKAK 710
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1622-1865 |
4.47e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.59 E-value: 4.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1622 RLAEMEQTVAEQDDSLSSLLVKLKKVSQDL----ERQREITELKVKEFENIKLQLQENHEDEVKKVKAEVEDLKYLLDQS 1697
Cdd:COG4913 611 KLAALEAELAELEEELAEAEERLEALEAELdalqERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAAL 690
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1698 QKESQCLKSELQAQKEANSRApTTTMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIiSATSQKEAHLNVQ 1777
Cdd:COG4913 691 EEQLEELEAELEELEEELDEL-KGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERF-AAALGDAVERELR 768
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1778 QIVDRHTRELKTQVEDLNENLLKL-KEALKTSKNRENSLTDNLNDL-----------NNELQKKQKAYNKILREKE---- 1841
Cdd:COG4913 769 ENLEERIDALRARLNRAEEELERAmRAFNREWPAETADLDADLESLpeylalldrleEDGLPEYEERFKELLNENSiefv 848
|
250 260
....*....|....*....|....*....
gi 2462534488 1842 -----EIDQENDELKRQIKRLTSGLQGKP 1865
Cdd:COG4913 849 adllsKLRRAIREIKERIDPLNDSLKRIP 877
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1002-1569 |
4.70e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 42.23 E-value: 4.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1002 SLKEQVE------SINKELEITK--EKLHTIEQAWEQETKLGNESSMDKAKKSITNSDIVSISKKITMLEMKELNERQRA 1073
Cdd:COG1196 204 PLERQAEkaeryrELKEELKELEaeLLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELEL 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1074 EHCQKMYEHLRTSLKQMEERNFELETKFAELTKINLDAQKVEQMLRDELADsvskavsdaDRQRILELEKNEMELKVEVS 1153
Cdd:COG1196 284 EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEE---------LEEELEELEEELEEAEEELE 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1154 KLRE-ISDIARRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKSLIAKLHQHNVSLQLSEATALGKLESITSKLQKME 1232
Cdd:COG1196 355 EAEAeLAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELE 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1233 AYNLRLEQKLDE-KEqalyyARLEGRNRAKHLRQTIQSLRRQFSGALPLAQQEKFSKTMIQLQNDKLKIMQEmknsQQEH 1311
Cdd:COG1196 435 EEEEEEEEALEEaAE-----EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEA----DYEG 505
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1312 RNMENKTLEMELKLKGLEELISTL------------------------KDTKGAQKVINWHMKIEELRLQELKLNRElvk 1367
Cdd:COG1196 506 FLEGVKAALLLAGLRGLAGAVAVLigveaayeaaleaalaaalqnivvEDDEVAAAAIEYLKAAKAGRATFLPLDKI--- 582
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1368 DKEEIKYLNNIISEYERTISSLEEEIVQQNKFHEERQMAWDQREVDLERQLDIFDRQQNEILNAAQKFEEATGSIPDPSl 1447
Cdd:COG1196 583 RARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGS- 661
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1448 plpnqleIALRKIKENIRIILETRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAEREKLIAELGRKEM 1527
Cdd:COG1196 662 -------LTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAER 734
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 2462534488 1528 EPKSHHTLKIAHQTIANMQARL--NQKEEVLKKYQRLLEKAREE 1569
Cdd:COG1196 735 EELLEELLEEEELLEEEALEELpePPDLEELERELERLEREIEA 778
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
1838-1979 |
4.76e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 42.15 E-value: 4.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1838 REKEEIDQENDELKRQIKRLtsglqgkpltdnkQSLIEELQRKVKKLENQLEGKVEEVD-----LKPMKeKNAKEELIRW 1912
Cdd:COG2433 399 REKEHEERELTEEEEEIRRL-------------EEQVERLEAEVEELEAELEEKDERIErlereLSEAR-SEERREIRKD 464
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2462534488 1913 EEGKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLFAKADKEKLTLQRKL----KTTGMTVDQVLGIRA 1979
Cdd:COG2433 465 REISRLDREIERLERELEEERERIEELKRKLERLKELWKLEHSGELVPVKVVekftKEAIRRLEEEYGLKE 535
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1720-2290 |
5.33e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 41.97 E-value: 5.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1720 TTTMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERiisatSQKEAHLNVQQIVDRHTRELKTQVEDLNENLL 1799
Cdd:PRK03918 188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEV-----KELEELKEEIEELEKELESLEGSKRKLEEKIR 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1800 KLKEALKTSKNRENSLTDNLNDLNnELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSglqgkpltdnkqsLIEELQR 1879
Cdd:PRK03918 263 ELEERIEELKKEIEELEEKVKELK-ELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEE-------------EINGIEE 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1880 KVKKLENqlegKVEEVDLKPMKEKNAKEELirwEEGKKWQAKIEGIRNKLKEKEGEVFTLT-KQLNTLKDLFAKADKEKL 1958
Cdd:PRK03918 329 RIKELEE----KEERLEELKKKLKELEKRL---EELEERHELYEEAKAKKEELERLKKRLTgLTPEKLEKELEELEKAKE 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1959 TLQRKLKTTGMTVDQVLGIRALESEKELEELKK--------RNLDLENDILYMRAHQALPRDSVVEDLHLQNRylQEKLH 2030
Cdd:PRK03918 402 EIEEEISKITARIGELKKEIKELKKAIEELKKAkgkcpvcgRELTEEHRKELLEEYTAELKRIEKELKEIEEK--ERKLR 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2031 ALEKQFSKDTYSKPSISGIES--DDHCQREQELQKENL-KLSSENIELKFQLEQANKDLPRLKNQVRDLKEMCEfLKKEK 2107
Cdd:PRK03918 480 KELRELEKVLKKESELIKLKElaEQLKELEEKLKKYNLeELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE-LKKKL 558
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2108 AEVQRKLGhvrgaELEKLKAHLGHQLSMHYESKTKGTEKIIAENERLRKELKKETDAAEKLRIAKNNLEILNEKMTVQLE 2187
Cdd:PRK03918 559 AELEKKLD-----ELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFE 633
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2188 ETGKRLQFAESRGPQLEGADSKswksivvtrMYETKLKELETDIAKKNQSITDLKQLVKEATEREQKVNKYNEDLEQQIK 2267
Cdd:PRK03918 634 ELAETEKRLEELRKELEELEKK---------YSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELE 704
|
570 580
....*....|....*....|...
gi 2462534488 2268 ILKHVPEGAETEQGLKRELQVLR 2290
Cdd:PRK03918 705 EREKAKKELEKLEKALERVEELR 727
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1630-2397 |
5.37e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 42.36 E-value: 5.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1630 VAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEFEniKLQLQENHEDEVKKVKAEVEDLKYLLDQSQKEsqclksELQ 1709
Cdd:TIGR02169 165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLE--RLRREREKAERYQALLKEKREYEGYELLKEKE------ALE 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1710 AQKEAnSRAPTTTMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRHTRELKT 1789
Cdd:TIGR02169 237 RQKEA-IERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKER 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1790 QVEDLNENLLKLKEALKTSKNRENSLTDNLND-------LNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLtsglq 1862
Cdd:TIGR02169 316 ELEDAEERLAKLEAEIDKLLAEIEELEREIEEerkrrdkLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDY----- 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1863 gkpltdnkQSLIEELQRKVKKLENQLEGKVEEVDLKPMKEKNAKEELIRWEEG-KKWQAKIEGIRNKLKEKEGEvftltk 1941
Cdd:TIGR02169 391 --------REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKiNELEEEKEDKALEIKKQEWK------ 456
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1942 qLNTLKDLFAKADKEKLTLQRKLkttgmtvdQVLGIRALESEKELEELKKRNLDLENDILYMRAHQALPRDSV------V 2015
Cdd:TIGR02169 457 -LEQLAADLSKYEQELYDLKEEY--------DRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIqgvhgtV 527
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2016 EDLhlqNRYLQEKLHALEKQFSkdtySKPSISGIESDDHCQREQELQKENLKLSSENIEL-KFQLEQANKDLPRLKNQVR 2094
Cdd:TIGR02169 528 AQL---GSVGERYATAIEVAAG----NRLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLnKMRDERRDLSILSEDGVIG 600
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2095 DLKEMCEFLKKEKAEV----------------QRKLGHVR-----GAELEKLKAHLGHQLSMHYESKTKGTEKiiAENER 2153
Cdd:TIGR02169 601 FAVDLVEFDPKYEPAFkyvfgdtlvvedieaaRRLMGKYRmvtleGELFEKSGAMTGGSRAPRGGILFSRSEP--AELQR 678
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2154 LRKELKKETDAAEKLRIAKNNLEILNEKMTVQLEETGKRLQFAESRGPQLEGADSKSwksivvtrmyETKLKELETDIAK 2233
Cdd:TIGR02169 679 LRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKL----------KERLEELEEDLSS 748
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2234 KNQSITDLKQ----LVKEATEREQKVNKYNEDLE-----------QQI-----KILKHVPEGAETEQGLKRELQVLRLAN 2293
Cdd:TIGR02169 749 LEQEIENVKSelkeLEARIEELEEDLHKLEEALNdlearlshsriPEIqaelsKLEEEVSRIEARLREIEQKLNRLTLEK 828
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2294 HQLDKEKAELIHQIEANKDQSGA-----ESTIPDADQLKEKIKdlETQLKMSDLEKQHLKEEikklkkelenfdpsffEE 2368
Cdd:TIGR02169 829 EYLEKEIQELQEQRIDLKEQIKSiekeiENLNGKKEELEEELE--ELEAALRDLESRLGDLK----------------KE 890
|
810 820
....*....|....*....|....*....
gi 2462534488 2369 IEDLKYNYKEevkknilLEEKVKKLSEQL 2397
Cdd:TIGR02169 891 RDELEAQLRE-------LERKIEELEAQI 912
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
2056-2257 |
5.71e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.67 E-value: 5.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2056 QREQELQKENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKEMCEFLKKEKAEVQRKLGHVRgAELEKLKAHLGHQLSM 2135
Cdd:COG4942 34 QEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR-AELEAQKEELAELLRA 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2136 HYESKTKGTEKIIAENE----------RLRKELKKETDAAEKLRIAKNNLEILNEKMTVQLEETGKRLQFAESRGPQLEG 2205
Cdd:COG4942 113 LYRLGRQPPLALLLSPEdfldavrrlqYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEA 192
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2462534488 2206 AdsKSWKSIVVTRMyETKLKELETDIAKKNQSITDLKQLVKEATEREQKVNK 2257
Cdd:COG4942 193 L--KAERQKLLARL-EKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
1470-2262 |
6.36e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 41.96 E-value: 6.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1470 TRATCKSLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAEREKLIAELGRKEMEPkSHHTLKIAHQTIANMQARL 1549
Cdd:TIGR00606 236 SREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKV-FQGTDEQLNDLYHNHQRTV 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1550 NQKEEVLKKYQRLLEKAREEQREIVKKHEEdLHILHHRLELQADssLNKFKQTAWDLMKQSPTPVPTNKHFIRLAEME-- 1627
Cdd:TIGR00606 315 REKERELVDCQRELEKLNKERRLLNQEKTE-LLVEQGRLQLQAD--RHQEHIRARDSLIQSLATRLELDGFERGPFSErq 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1628 -----QTVAEQDDSLSSLLVKLKKVSQDLER--QREITELKVKEFE-----NIKLQLQENHEDEVKKVKAEVEDLKYLLD 1695
Cdd:TIGR00606 392 iknfhTLVIERQEDEAKTAAQLCADLQSKERlkQEQADEIRDEKKGlgrtiELKKEILEKKQEELKFVIKELQQLEGSSD 471
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1696 QSQKESQCLKSELQAQKEANSRAPTTTMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIIsATSQKEAHLN 1775
Cdd:TIGR00606 472 RILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEML-TKDKMDKDEQ 550
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1776 VQQIVDRHTRELKTQVEDLnENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIK 1855
Cdd:TIGR00606 551 IRKIKSRHSDELTSLLGYF-PNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLF 629
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1856 RLTSglqgkplTDNKQSLIEELQRKVKKLENQL---------------EGKVEEVDLKPMKEKNAKEELIRWEEGKKWQA 1920
Cdd:TIGR00606 630 DVCG-------SQDEESDLERLKEEIEKSSKQRamlagatavysqfitQLTDENQSCCPVCQRVFQTEAELQEFISDLQS 702
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1921 KIEGIRNKLKEKEGEVFTLTKQLNtlkDLFAKADKEKLTLQRKLKttgmtvdQVLGIRALESEKELEELKKRNLDLENDI 2000
Cdd:TIGR00606 703 KLRLAPDKLKSTESELKKKEKRRD---EMLGLAPGRQSIIDLKEK-------EIPELRNKLQKVNRDIQRLKNDIEEQET 772
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2001 LYMRAHQALPRDSVVEDLHLQNRYLQEKLHALEKQFSKDTYSKPSISGIESDDHCQREQELQKENLKLSSENIELKFQLE 2080
Cdd:TIGR00606 773 LLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLI 852
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2081 QANKDlprlknQVRDLKEMCEFLKKEKAEVQRKLGHvRGAELEKlkahlghqlsmhyesktkgTEKIIAENERLRKELKK 2160
Cdd:TIGR00606 853 QDQQE------QIQHLKSKTNELKSEKLQIGTNLQR-RQQFEEQ-------------------LVELSTEVQSLIREIKD 906
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2161 ETDAAEKLRIAKNNLEILNEKMTVQLEETGKRLQFaesrgpQLEGADSKSWKSIVVTRMYETKLKELETDiaKKNQSITD 2240
Cdd:TIGR00606 907 AKEQDSPLETFLEKDQQEKEELISSKETSNKKAQD------KVNDIKEKVKNIHGYMKDIENKIQDGKDD--YLKQKETE 978
|
810 820
....*....|....*....|..
gi 2462534488 2241 LKQLVKEATEREQKVNKYNEDL 2262
Cdd:TIGR00606 979 LNTVNAQLEECEKHQEKINEDM 1000
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1293-1700 |
6.52e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.98 E-value: 6.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1293 LQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDtkgaqkvinwhmKIEELRLQELKLNRELVKDKEEI 1372
Cdd:TIGR02169 693 LQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKE------------RLEELEEDLSSLEQEIENVKSEL 760
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1373 KYLNNIISEYERTISSLEEEIvqqnkfheerqmawdqreVDLERQLDifDRQQNEILNAAQKFEEATGSIpdpslplpnq 1452
Cdd:TIGR02169 761 KELEARIEELEEDLHKLEEAL------------------NDLEARLS--HSRIPEIQAELSKLEEEVSRI---------- 810
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1453 leialRKIKENIRIILETRATCK-SLEEKLKEKESALRLAEQNILSRDKVINELRLRLPATAERekliaelgrkemepks 1531
Cdd:TIGR02169 811 -----EARLREIEQKLNRLTLEKeYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEE---------------- 869
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1532 hhtlkiahqtIANMQARLNQKEEVLKKYQRLLEKAREEQREIVKKHEEdlhilhhrlelqADSSLNKFKQTAWDLMKQSP 1611
Cdd:TIGR02169 870 ----------LEELEAALRDLESRLGDLKKERDELEAQLRELERKIEE------------LEAQIEKKRKRLSELKAKLE 927
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1612 TPVPTNKHFIRLAEMEQTVAEQDDSLSSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQEnHEDEVKKVKAEVEDLK 1691
Cdd:TIGR02169 928 ALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDE-LKEKRAKLEEERKAIL 1006
|
....*....
gi 2462534488 1692 YLLDQSQKE 1700
Cdd:TIGR02169 1007 ERIEEYEKK 1015
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
874-1402 |
6.75e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 41.97 E-value: 6.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 874 EMKKILAENSRKITVLQVNEKSLIRQYTTLVELERQLRK------ENEKQKNELLSMEAEVCEKIGCLQRFKEMAIFKIA 947
Cdd:PRK03918 197 EKEKELEEVLREINEISSELPELREELEKLEKEVKELEElkeeieELEKELESLEGSKRKLEEKIRELEERIEELKKEIE 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 948 ALQKVVDNsvsLSELELANKQYNELTAKYRDILQKDNMLVQRTSNLEHLECENISLKEQVESINKELEITKEKLHTIEQA 1027
Cdd:PRK03918 277 ELEEKVKE---LKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKR 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1028 WEQETKLGNESSMDKAKKsitnSDIVSISKKITMLEMKELNE-----RQRAEHCQKMYEHLRTSLKQMEERNFELETKFA 1102
Cdd:PRK03918 354 LEELEERHELYEEAKAKK----EELERLKKRLTGLTPEKLEKeleelEKAKEEIEEEISKITARIGELKKEIKELKKAIE 429
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1103 ELTKIN----LDAQKVEQMLRDELADSVSKAVSDAdRQRILELEKNEMELKVEVSKLREISDIARRQVEILNAQQQSRDK 1178
Cdd:PRK03918 430 ELKKAKgkcpVCGRELTEEHRKELLEEYTAELKRI-EKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKEL 508
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1179 EVESLRMQLLDYQAQSDEKSLIAKLHQHNVSLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQALyyaRLEGRN 1258
Cdd:PRK03918 509 EEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKEL---EELGFE 585
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1259 RAKHLRQTIQSLrrqfsgalplaqqEKFSKTMIQLQNDKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDT 1338
Cdd:PRK03918 586 SVEELEERLKEL-------------EPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEEL 652
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2462534488 1339 kgaqKVINWHMKIEELRLQELKLNRELVKDKEEIKYLNNIISEYERTISSLEEEIVQQNKFHEE 1402
Cdd:PRK03918 653 ----EKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKE 712
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1817-2290 |
7.28e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 41.59 E-value: 7.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1817 DNLNDLNNELQKKQKAYNKILREKEEIDqenDELKRQIKRLTSGLQgkpLTDNKQSLIEELQRKVKKLENQLEgKVEEvd 1896
Cdd:PRK03918 165 KNLGEVIKEIKRRIERLEKFIKRTENIE---ELIKEKEKELEEVLR---EINEISSELPELREELEKLEKEVK-ELEE-- 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1897 LKPMKEKNAKEELIRWEEGKKWQAKIEGIRNKLKEKEGEVFTLTKQLNTLKDLfaKADKEKLTLQRKLKTTGMTVDQVLG 1976
Cdd:PRK03918 236 LKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL--KEKAEEYIKLSEFYEEYLDELREIE 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1977 IRALESEKELEELKKRNLDLENDilymrahqalprDSVVEDLHLQNRYLQEKLHALE---KQFSKDTYSKPSISGIESDD 2053
Cdd:PRK03918 314 KRLSRLEEEINGIEERIKELEEK------------EERLEELKKKLKELEKRLEELEerhELYEEAKAKKEELERLKKRL 381
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2054 HCQREQELQKENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKEMCEFLKKEKAEVQrklghVRGAELEKlkahlghql 2133
Cdd:PRK03918 382 TGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCP-----VCGRELTE--------- 447
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2134 smhyESKTKGTEKIIAENERLRKELKKETDAAEKLRIAKNNLE--ILNEKMTVQLEETGKRLQFAESRgpqLEGADSKSW 2211
Cdd:PRK03918 448 ----EHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEkvLKKESELIKLKELAEQLKELEEK---LKKYNLEEL 520
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 2212 KSivVTRMYET---KLKELETDIAKKNQSITDLKQLVKEATEREQKVNKYNEDLEQQIKILKHvpEGAETEQGLKRELQV 2288
Cdd:PRK03918 521 EK--KAEEYEKlkeKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEE--LGFESVEELEERLKE 596
|
..
gi 2462534488 2289 LR 2290
Cdd:PRK03918 597 LE 598
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
1782-1933 |
7.93e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 41.74 E-value: 7.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1782 RHTRELKTQVEDLNENLLKLKEALKtskNRENSLtdnlndlnneLQKKQKAYNKILRE-KEEIDQENDELKRQIKRLTSG 1860
Cdd:PRK00409 537 EEAEALLKEAEKLKEELEEKKEKLQ---EEEDKL----------LEEAEKEAQQAIKEaKKEADEIIKELRQLQKGGYAS 603
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2462534488 1861 LQGKPLTDNKQSLIEELQRKVKKL----ENQLEGKV-EEVDLKPMkekNAKEELIRWEEGKKWQAKIEGIRNKLKEKE 1933
Cdd:PRK00409 604 VKAHELIEARKRLNKANEKKEKKKkkqkEKQEELKVgDEVKYLSL---GQKGEVLSIPDDKEAIVQAGIMKMKVPLSD 678
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
1096-1192 |
8.91e-03 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 40.72 E-value: 8.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1096 ELETKFAELT-KINLDAQKVEQmLRDELAD-SVSKAVSDADRQRIL-----------ELEKNEMELKVEVSKLREISDIA 1162
Cdd:PRK09039 57 RLNSQIAELAdLLSLERQGNQD-LQDSVANlRASLSAAEAERSRLQallaelagagaAAEGRAGELAQELDSEKQVSARA 135
|
90 100 110
....*....|....*....|....*....|
gi 2462534488 1163 RRQVEILNAQqqsrdkeVESLRMQLLDYQA 1192
Cdd:PRK09039 136 LAQVELLNQQ-------IAALRRQLAALEA 158
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
129-989 |
9.07e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 41.50 E-value: 9.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 129 RELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQidsQKETLLSRRGEDSDYRSQL 208
Cdd:pfam02463 166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEE---EYLLYLDYLKLNEERIDLL 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 209 SKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVhQTDNVIDQLKKENDHYQLQVQEL 288
Cdd:pfam02463 243 QELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEEL-KSELLKLERRKVDDEEKLKESEK 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 289 TDLLKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEIIEYQQMLHNLREKLKNAQLDADKSNVMALQQGIQERDSQIKMLT 368
Cdd:pfam02463 322 EKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKS 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 369 EQVEQYTKEMEKNTCIIEDLKNELQR------NKGASTLSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELV 442
Cdd:pfam02463 402 EEEKEAQLLLELARQLEDLLKEEKKEeleileEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVK 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 443 EALKRLK----DYESGVYGLEDAVVEIKNCKNQIKIRDREIEILTKEINKLELKISDFLDENEALRERVGLEPKTMIDLT 518
Cdd:pfam02463 482 LQEQLELllsrQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVE 561
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 519 EFRNSKHLKQQQYRAENQILLKEIESLEEERLDLKKKIRQMAQERGKRSATSGLTTEDLNLTENISQGDRISERKLDLLS 598
Cdd:pfam02463 562 ERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESA 641
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 599 LKNMSEAQSKNEFLSRELIEKERDlerSRTVIAKFQNKLKELVEENKQLEEGMKEILQAIKEMQKDPDVKGGETSLIIPS 678
Cdd:pfam02463 642 KAKESGLRKGVSLEEGLAEKSEVK---ASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLE 718
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 679 LERLVNAIESKNAEGIFDASLHLKAQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKETSLLRQSEGSNV 758
Cdd:pfam02463 719 AEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKA 798
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 759 VFKgidlpdgiapsSASIINSQNEYLIHLLQELENKEKKLKNLEDSLEDYNRK--FAVIRHQQSLLYKEYLSEKETWKTE 836
Cdd:pfam02463 799 QEE-----------ELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALelKEEQKLEKLAEEELERLEEEITKEE 867
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 837 SKTIKEEKRKLEDQVQQDAIKVKEYNNLLNALQMDSDEMKKILAENSRKITVLQVNEKSLIRQYTTLVELERQLRKENEK 916
Cdd:pfam02463 868 LLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADE 947
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2462534488 917 QKNELLSMEAEVCEKIGCLQRFKEMAIFKIAALQKVVDNSVSLSELELankQYNELTAKYRDILQKDNMLVQR 989
Cdd:pfam02463 948 KEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDEL---EKERLEEEKKKLIRAIIEETCQ 1017
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1731-1894 |
9.39e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.44 E-value: 9.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1731 KSQLALKEKQQKALSRALLELRAEMTAAAEERIiSATSQKEAHLNVQQI---------VDRHTRELKTQVEDLNENLLKL 1801
Cdd:COG4913 609 RAKLAALEAELAELEEELAEAEERLEALEAELD-ALQERREALQRLAEYswdeidvasAEREIAELEAELERLDASSDDL 687
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462534488 1802 KEalktsknrensLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQGKP---------------- 1865
Cdd:COG4913 688 AA-----------LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEdlarlelralleerfa 756
|
170 180 190
....*....|....*....|....*....|....*....
gi 2462534488 1866 ----------LTDNKQSLIEELQRKVKKLENQLEGKVEE 1894
Cdd:COG4913 757 aalgdavereLRENLEERIDALRARLNRAEEELERAMRA 795
|
|
| |
