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Conserved domains on  [gi|2462497696|ref|XP_054188451|]
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src substrate cortactin isoform X3 [Homo sapiens]

Protein Classification

HS1_rep domain-containing protein( domain architecture ID 11129676)

HS1_rep domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HS1_rep pfam02218
Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in ...
 157-192 2.32e-15

Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in cortactin and four copies are found in HS1. The repeats are always found amino terminal to an SH3 domain pfam00018.


:

Pssm-ID: 460497 [Multi-domain]  Cd Length: 36  Bit Score: 68.35  E-value: 2.32e-15
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2462497696 157 GFGGKYGVQADRVDKSAVGFDYQGKTEKHESQRDYS 192
Cdd:pfam02218   1 GFGGKFGVQKDRQDKSAVGWDYKEKVEKHASQKDYS 36
HS1_rep pfam02218
Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in ...
 120-155 7.25e-15

Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in cortactin and four copies are found in HS1. The repeats are always found amino terminal to an SH3 domain pfam00018.


:

Pssm-ID: 460497 [Multi-domain]  Cd Length: 36  Bit Score: 66.81  E-value: 7.25e-15
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2462497696 120 GFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYS 155
Cdd:pfam02218   1 GFGGKFGVQKDRQDKSAVGWDYKEKVEKHASQKDYS 36
HS1_rep pfam02218
Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in ...
 194-228 1.14e-13

Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in cortactin and four copies are found in HS1. The repeats are always found amino terminal to an SH3 domain pfam00018.


:

Pssm-ID: 460497 [Multi-domain]  Cd Length: 36  Bit Score: 63.73  E-value: 1.14e-13
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2462497696 194 GFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDY 228
Cdd:pfam02218   1 GFGGKFGVQKDRQDKSAVGWDYKEKVEKHASQKDY 35
HS1_rep pfam02218
Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in ...
 231-263 2.83e-13

Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in cortactin and four copies are found in HS1. The repeats are always found amino terminal to an SH3 domain pfam00018.


:

Pssm-ID: 460497 [Multi-domain]  Cd Length: 36  Bit Score: 62.57  E-value: 2.83e-13
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2462497696 231 GFGGKFGVQTDRQDKCALGWDHQEKLQLHESQK 263
Cdd:pfam02218   1 GFGGKFGVQKDRQDKSAVGWDYKEKVEKHASQK 33
HS1_rep pfam02218
Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in ...
 83-116 2.87e-12

Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in cortactin and four copies are found in HS1. The repeats are always found amino terminal to an SH3 domain pfam00018.


:

Pssm-ID: 460497 [Multi-domain]  Cd Length: 36  Bit Score: 59.88  E-value: 2.87e-12
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2462497696  83 GYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVD 116
Cdd:pfam02218   1 GFGGKFGVQKDRQDKSAVGWDYKEKVEKHASQKD 34
 
Name Accession Description Interval E-value
HS1_rep pfam02218
Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in ...
 157-192 2.32e-15

Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in cortactin and four copies are found in HS1. The repeats are always found amino terminal to an SH3 domain pfam00018.


Pssm-ID: 460497 [Multi-domain]  Cd Length: 36  Bit Score: 68.35  E-value: 2.32e-15
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2462497696 157 GFGGKYGVQADRVDKSAVGFDYQGKTEKHESQRDYS 192
Cdd:pfam02218   1 GFGGKFGVQKDRQDKSAVGWDYKEKVEKHASQKDYS 36
HS1_rep pfam02218
Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in ...
 120-155 7.25e-15

Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in cortactin and four copies are found in HS1. The repeats are always found amino terminal to an SH3 domain pfam00018.


Pssm-ID: 460497 [Multi-domain]  Cd Length: 36  Bit Score: 66.81  E-value: 7.25e-15
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2462497696 120 GFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYS 155
Cdd:pfam02218   1 GFGGKFGVQKDRQDKSAVGWDYKEKVEKHASQKDYS 36
HS1_rep pfam02218
Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in ...
 194-228 1.14e-13

Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in cortactin and four copies are found in HS1. The repeats are always found amino terminal to an SH3 domain pfam00018.


Pssm-ID: 460497 [Multi-domain]  Cd Length: 36  Bit Score: 63.73  E-value: 1.14e-13
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2462497696 194 GFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDY 228
Cdd:pfam02218   1 GFGGKFGVQKDRQDKSAVGWDYKEKVEKHASQKDY 35
HS1_rep pfam02218
Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in ...
 231-263 2.83e-13

Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in cortactin and four copies are found in HS1. The repeats are always found amino terminal to an SH3 domain pfam00018.


Pssm-ID: 460497 [Multi-domain]  Cd Length: 36  Bit Score: 62.57  E-value: 2.83e-13
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2462497696 231 GFGGKFGVQTDRQDKCALGWDHQEKLQLHESQK 263
Cdd:pfam02218   1 GFGGKFGVQKDRQDKSAVGWDYKEKVEKHASQK 33
HS1_rep pfam02218
Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in ...
 83-116 2.87e-12

Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in cortactin and four copies are found in HS1. The repeats are always found amino terminal to an SH3 domain pfam00018.


Pssm-ID: 460497 [Multi-domain]  Cd Length: 36  Bit Score: 59.88  E-value: 2.87e-12
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2462497696  83 GYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVD 116
Cdd:pfam02218   1 GFGGKFGVQKDRQDKSAVGWDYKEKVEKHASQKD 34
 
Name Accession Description Interval E-value
HS1_rep pfam02218
Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in ...
 157-192 2.32e-15

Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in cortactin and four copies are found in HS1. The repeats are always found amino terminal to an SH3 domain pfam00018.


Pssm-ID: 460497 [Multi-domain]  Cd Length: 36  Bit Score: 68.35  E-value: 2.32e-15
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2462497696 157 GFGGKYGVQADRVDKSAVGFDYQGKTEKHESQRDYS 192
Cdd:pfam02218   1 GFGGKFGVQKDRQDKSAVGWDYKEKVEKHASQKDYS 36
HS1_rep pfam02218
Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in ...
 120-155 7.25e-15

Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in cortactin and four copies are found in HS1. The repeats are always found amino terminal to an SH3 domain pfam00018.


Pssm-ID: 460497 [Multi-domain]  Cd Length: 36  Bit Score: 66.81  E-value: 7.25e-15
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2462497696 120 GFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYS 155
Cdd:pfam02218   1 GFGGKFGVQKDRQDKSAVGWDYKEKVEKHASQKDYS 36
HS1_rep pfam02218
Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in ...
 194-228 1.14e-13

Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in cortactin and four copies are found in HS1. The repeats are always found amino terminal to an SH3 domain pfam00018.


Pssm-ID: 460497 [Multi-domain]  Cd Length: 36  Bit Score: 63.73  E-value: 1.14e-13
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2462497696 194 GFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDY 228
Cdd:pfam02218   1 GFGGKFGVQKDRQDKSAVGWDYKEKVEKHASQKDY 35
HS1_rep pfam02218
Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in ...
 231-263 2.83e-13

Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in cortactin and four copies are found in HS1. The repeats are always found amino terminal to an SH3 domain pfam00018.


Pssm-ID: 460497 [Multi-domain]  Cd Length: 36  Bit Score: 62.57  E-value: 2.83e-13
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2462497696 231 GFGGKFGVQTDRQDKCALGWDHQEKLQLHESQK 263
Cdd:pfam02218   1 GFGGKFGVQKDRQDKSAVGWDYKEKVEKHASQK 33
HS1_rep pfam02218
Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in ...
 83-116 2.87e-12

Repeat in HS1/Cortactin; The function of this repeat is unknown. Seven copies are found in cortactin and four copies are found in HS1. The repeats are always found amino terminal to an SH3 domain pfam00018.


Pssm-ID: 460497 [Multi-domain]  Cd Length: 36  Bit Score: 59.88  E-value: 2.87e-12
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2462497696  83 GYGGKFGVEQDRMDKSAVGHEYQSKLSKHCSQVD 116
Cdd:pfam02218   1 GFGGKFGVQKDRQDKSAVGWDYKEKVEKHASQKD 34
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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