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glutathione hydrolase 5 proenzyme isoform X11 [Homo sapiens]
Protein Classification
gamma-glutamyltransferase family protein ( domain architecture ID 10470232 )
gamma-glutamyltransferase family protein exhibits gamma-glutamyltranspeptidase and/or cephalosporin acylase and/or glutathione hydrolase activity, all involving the hydrolytic splitting of a peptide-like C-N bond
List of domain hits
Name
Accession
Description
Interval
E-value
G_glu_transpept
pfam01019 Gamma-glutamyltranspeptidase;
58-544
0e+00
Gamma-glutamyltranspeptidase;
Pssm-ID: 425991
Cd Length: 499
Bit Score: 541.80
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 58 RA IL QQQ G SP VDA TI AA LV C TS VV N P Q S M G L GGG VIFT IY NVT TGKV E VI N ARET V PA SHAPSLL D QCAQALPLG TG AQW 137
Cdd:pfam01019 1 LD IL RKG G NA VDA AV AA AL C LG VV E P H S S G I GGG GFML IY DAK TGKV L VI D ARET A PA AATKDMF D GKGDSKLSL TG GLA 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 138 I GVPGE LR G Y AEAH R R H GRLPWA Q L FQ P T I A L L R G G HV V A P V L S R F L HNSIL R P s LQAST LR QL F FNGTEP L RPQDP L PW 217
Cdd:pfam01019 81 V GVPGE VA G L AEAH K R Y GRLPWA D L LE P A I K L A R D G FP V S P A L A R A L ARAEE R L - RADPG LR KI F LPTGRV L KAGEL L KQ 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 218 PALA T TLE TV A T EG VEV FY T G R L G Q M LV E D IAKE G SQL T LQ DLA KFQPEVVDA L EVPL G D YT L YSPPP PA GG AI L SF ILN 297
Cdd:pfam01019 160 PALA K TLE LI A E EG PDA FY R G E L A Q Q LV A D LQAN G GII T AE DLA NYRVKIREP L SADY G G YT V YSPPP SS GG IA L LQ ILN 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 298 V L R GF NF S TES marpe GRVNVY H H L V E TL K F A KGQ R W R - LGDP RSH P KLQ nas RD LL GETL A QLIRQQ I DGRGDHQL S H y 376
Cdd:pfam01019 240 I L E GF DL S SLL ----- NSAEYL H L L I E AM K L A YAD R T R y LGDP DFV P VPV --- EN LL SPEY A KERAKL I NPNAAFPS S Y - 310
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 377 slaea WGHGT GT S H V SV LGE DG S AV AA TSTIN TP FG AM V YS P R TGI I LNNE LL D LCERCPRGS G TT PSP DA vcsavsgdr 456
Cdd:pfam01019 311 ----- APEDG GT T H F SV VDR DG N AV SF TSTIN LG FG SG V VV P G TGI L LNNE MD D FSTPPGNAF G LD PSP AN --------- 376
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 457 vggapgrcw PPV PG E R SP SSM V P S I LINK a QGSK LV I G GA GG EL IISAV A Q A I MSK L W LG F DL RA A IA AP IL H VNSKGCV 536
Cdd:pfam01019 377 --------- AIA PG K R PL SSM A P T I VLDD - GKPV LV V G AP GG SR IISAV L Q V I VNV L D LG L DL QQ A VD AP RI H HQLPDVL 446
....*...
gi 2462584680 537 E Y EP N F SQ 544
Cdd:pfam01019 447 E V EP G F PE 454
Name
Accession
Description
Interval
E-value
G_glu_transpept
pfam01019 Gamma-glutamyltranspeptidase;
58-544
0e+00
Gamma-glutamyltranspeptidase;
Pssm-ID: 425991
Cd Length: 499
Bit Score: 541.80
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 58 RA IL QQQ G SP VDA TI AA LV C TS VV N P Q S M G L GGG VIFT IY NVT TGKV E VI N ARET V PA SHAPSLL D QCAQALPLG TG AQW 137
Cdd:pfam01019 1 LD IL RKG G NA VDA AV AA AL C LG VV E P H S S G I GGG GFML IY DAK TGKV L VI D ARET A PA AATKDMF D GKGDSKLSL TG GLA 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 138 I GVPGE LR G Y AEAH R R H GRLPWA Q L FQ P T I A L L R G G HV V A P V L S R F L HNSIL R P s LQAST LR QL F FNGTEP L RPQDP L PW 217
Cdd:pfam01019 81 V GVPGE VA G L AEAH K R Y GRLPWA D L LE P A I K L A R D G FP V S P A L A R A L ARAEE R L - RADPG LR KI F LPTGRV L KAGEL L KQ 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 218 PALA T TLE TV A T EG VEV FY T G R L G Q M LV E D IAKE G SQL T LQ DLA KFQPEVVDA L EVPL G D YT L YSPPP PA GG AI L SF ILN 297
Cdd:pfam01019 160 PALA K TLE LI A E EG PDA FY R G E L A Q Q LV A D LQAN G GII T AE DLA NYRVKIREP L SADY G G YT V YSPPP SS GG IA L LQ ILN 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 298 V L R GF NF S TES marpe GRVNVY H H L V E TL K F A KGQ R W R - LGDP RSH P KLQ nas RD LL GETL A QLIRQQ I DGRGDHQL S H y 376
Cdd:pfam01019 240 I L E GF DL S SLL ----- NSAEYL H L L I E AM K L A YAD R T R y LGDP DFV P VPV --- EN LL SPEY A KERAKL I NPNAAFPS S Y - 310
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 377 slaea WGHGT GT S H V SV LGE DG S AV AA TSTIN TP FG AM V YS P R TGI I LNNE LL D LCERCPRGS G TT PSP DA vcsavsgdr 456
Cdd:pfam01019 311 ----- APEDG GT T H F SV VDR DG N AV SF TSTIN LG FG SG V VV P G TGI L LNNE MD D FSTPPGNAF G LD PSP AN --------- 376
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 457 vggapgrcw PPV PG E R SP SSM V P S I LINK a QGSK LV I G GA GG EL IISAV A Q A I MSK L W LG F DL RA A IA AP IL H VNSKGCV 536
Cdd:pfam01019 377 --------- AIA PG K R PL SSM A P T I VLDD - GKPV LV V G AP GG SR IISAV L Q V I VNV L D LG L DL QQ A VD AP RI H HQLPDVL 446
....*...
gi 2462584680 537 E Y EP N F SQ 544
Cdd:pfam01019 447 E V EP G F PE 454
Ggt
COG0405 Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
54-544
6.56e-100
Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
Pssm-ID: 440174
Cd Length: 507
Bit Score: 311.60
E-value: 6.56e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 54 S DI G RA IL QQQ G SP VDA TI AA LVCTS VV N P Q S M G L GGG VIFT IY NVTT GKV EVINA R E T V PA SHA P SLLDQCAQAL P l GT 133
Cdd:COG0405 10 S QA G LE IL RAG G NA VDA AV AA AAALA VV E P H S S G I GGG GFAL IY DAKD GKV TALDG R G T A PA AAT P DMYLDAGDEI P - VR 88
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 134 G AQWI GVPG ELR G YAE AH R R H G R LP W A Q L FQ P T I A L LRG G HV V A P V L SRF L HNS il RPS L QAS - TLRQL F FNGTE P LRPQ 212
Cdd:COG0405 89 G PLAV GVPG TVA G WEA AH E R Y G T LP L A E L LA P A I R L AED G FP V S P R L AAL L AAA -- AER L ARD p GAAAI F LPDGR P PKAG 166
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 213 D P L PW P A LA T TL ETV A T EG VEV FY T G RLGQML V EDIAKE G SQ LTL Q DLA KFQP E VVDA L EVPLGD YT L YS P PPP AG G AI L 292
Cdd:COG0405 167 D I L RQ P D LA A TL RRI A E EG ADA FY R G EIAEAI V AAVQAA G GL LTL E DLA AYRA E WREP L SGTYRG YT V YS M PPP SQ G IA L 246
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 293 SF ILN V L R GF NFSTESMARP E G rvnv Y H H L V E TL K -- FA KGQ R W r LGDP RSHP klq NASRD LL GETL A QLIRQQ ID GRGD 370
Cdd:COG0405 247 LQ ILN I L E GF DLAALGPDSA E Y ---- V H L L A E AM K la FA DRD R Y - LGDP DFVD --- VPVEG LL SPAY A AERAAL ID PDRA 318
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 371 HQLSHYSLAEAWGH G t G T S H V SV LGE DG S AV AA T ST I NTP FG AM V YS P R TG II LNN elldlcercp RG SGTTPS P davcs 450
Cdd:COG0405 319 TPSPRPGDPTGPES G - D T T H L SV VDR DG N AV SL T QS I YGG FG SG V VV P G TG FL LNN ---------- RG DDFSLD P ----- 382
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 451 avsgdrvg G A P GR cwp PV PG E R SP S S M V P S I LI n K AQGSK LV I G GA GG EL I ISA V A Q AIMSK L WL G FDLRA A IA AP - IL H 529
Cdd:COG0405 383 -------- G H P NA --- LA PG K R PR S T M S P T I VL - K DGKPV LV F G SP GG SR I PQT V L Q VLLNV L DF G MNPQE A VD AP r WH H 450
490
....*....|....*
gi 2462584680 530 VNSKGCV E Y EP N F SQ 544
Cdd:COG0405 451 QGLPDTL E L EP R F PP 465
g_glut_trans
TIGR00066 gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of ...
54-543
6.63e-83
gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of this family have antibiotic synthesis or resistance activities. In the case of a cephalosporin acylase from Pseudomonas sp., the enzyme was shown to retain some gamma-glutamyltranspeptidase activity. Other, more distantly related proteins have ggt-related activities and score below the trusted cutoff. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs]
Pssm-ID: 129176
Cd Length: 516
Bit Score: 267.79
E-value: 6.63e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 54 S D IG RA IL QQQ G SPV DA TI A ALVCTS VV N P QSM GLGGG VIFT I YNVT T GKVEV I NA RE TV PA - SHAPSL LD QCAQA LP LG 132
Cdd:TIGR00066 11 S E IG ED IL KEG G NAF DA AV A VGLALA VV E P FMT GLGGG GFML I SGKK T KDTTA I DF RE RA PA k ATRDMF LD KSGNP LP GK 90
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 133 -- TG AQW IGVPG ELR G YAE A HRRH G R LP WAQ L FQ P T I A L L R G G HVVAPV L SRF L HNSILRPSLQASTLRQL F FNGTE PL R 210
Cdd:TIGR00066 91 sl TG GLA IGVPG TVA G LEA A LKKY G T LP LKD L IE P A I K L A R N G FPINEA L ADT L ELYEEVLLTTKEDSKDI F NPTGK PL K 170
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 211 PQ D P L PWPA LA TT LE TV A TE G VEV FY T G RLGQMLVEDIA K E G SQL T LQ DLA KFQP E V vdal EV PL - GDY TL Y S ---- PPP 285
Cdd:TIGR00066 171 EG D T L VQKD LA KS LE LI A EN G PDA FY K G DIAESIIDTLQ K N G GIM T KK DLA AYDV E I ---- RK PL s GDY RG Y Q vytt PPP 246
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 286 PA GG AI L SFI LN V L RG F NF S tesm ARPE G RVNV Y HH L V E TL K FAKGQ R W R - LGDP RSHPK lqn ASRD LL GETL A QLIR Q Q 364
Cdd:TIGR00066 247 SS GG IH L LQA LN I L EN F DL S ---- QYGD G SAET Y QL L A E AM K LSYAD R S R y LGDP EFVDV --- PLEE LL DKRY A KELA Q S 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 365 I D - GRG D HQLSH Y SL A EAWGH G TG T S H V SV LGE DG S AV AA T S TIN TP FG AM V YS P R TGI I LNNE LL D LCER cprgsgttp 443
Cdd:TIGR00066 320 I K i NKV D PKSTI Y PG A YQPNE G SQ T T H F SV VDR DG N AV SL T T TIN LE FG SG V HA P D TGI L LNNE MD D FSLK --------- 390
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 444 spdavcsavsgdrvgga PG RCWPPV P GE R SP SSM V P S I LINKAQ g SK LV I G GA GG EL II SA V A Q A I MSKLWL G FD L RA A I 523
Cdd:TIGR00066 391 ----------------- PG GANAVE P NK R PL SSM A P T I VLKDGK - PD LV V G SP GG SR II TT V L Q T I VRHIDY G MP L AE A V 452
490 500
....*....|....*....|.
gi 2462584680 524 AA P IL H VNS - KGCVEY E PN F S 543
Cdd:TIGR00066 453 SE P RI H HQW l PDELRL E KG F P 473
PLN02180
PLN02180 gamma-glutamyl transpeptidase 4
49-543
1.65e-73
gamma-glutamyl transpeptidase 4
Pssm-ID: 177836
Cd Length: 639
Bit Score: 246.51
E-value: 1.65e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 49 D SKV CS D IG RAI L QQQ G SP VDA TI A ALV C TS VVNP Q S M G L GGG VIFTIYNVTTG K V E VINA RET V P ASHAPSLLDQC A Q A 128
Cdd:PLN02180 88 D DAR CS E IG ASV L RRG G HA VDA AV A ITL C IG VVNP M S S G I GGG SFLIVSSQKDS K A E AFDM RET A P LAASKDMYKND A S A 167
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 129 LP LG tg A QWI GVPGE LR G YA EA HR R H GRLPW AQ LF Q P T I A L L R G G H VV A P V L SRFLHNSILR p S L QAST LR QL F FNGTEP 208
Cdd:PLN02180 168 KS LG -- A LSM GVPGE IA G LY EA WK R Y GRLPW KP LF E P A I E L A R D G F VV H P Y L GKAISSHAAM - I L KDPG LR SV F SRNGQV 244
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 209 L R P QDPLPW P A LA TT LET VATE G VEV FY T G RL G QM LV E D IA K E G SQL T LQ DL AKFQPE V V DA LE V PLGD YT LYSP PPP A G 288
Cdd:PLN02180 245 L K P GETCYN P E LA QS LET ISEQ G PGA FY N G TI G EK LV K D VK K A G GII T MD DL RSYEVL V T DA MS V DVMG YT IHGM PPP S G 324
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 289 G AI - L S FILNV L RGF - N FS T E S marpe GR VNVY H H L V E TL K FAKGQ R WR LGDP r SHPKLQ NA SRDL L GETL A QL I RQQ I D 366
Cdd:PLN02180 325 G TL g F S MVIDI L DSY s N LY T A S ----- GR ELGL H R L I E AM K HMFAA R MD LGDP - EFVNIT NA MNQM L SKAH A EE I QKR I F 398
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 367 GRGDHQLSH Y SLAEAWGHGT GTSH VSVLGE D GSA V AA TST I N TP FGA M V Y SP R TGI I LNNE LL D L cercprgsg T TP spd 446
Cdd:PLN02180 399 DNTTFPPEY Y LNRWSQLRDQ GTSH FCIVDA D RNS V SM TST V N YG FGA G V L SP S TGI V LNNE MD D F --------- S TP --- 466
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 447 avc SAVSG D RVGG AP GRCWP pv P GE R SP SSM V P s IL I N K AQGSKLVI GGAGG EL II S AV A Q AIMSKLW L GFDLRA A I - A A 525
Cdd:PLN02180 467 --- AEITP D MLPP AP TNFIE -- P NK R PL SSM T P - LV I T K DGEFVAAL GGAGG MH II P AV L Q VFLNCFV L NMKPKE A V e S A 540
490
....*....|....*...
gi 2462584680 526 P I L H VNSKGC V E YE p NF S 543
Cdd:PLN02180 541 R I Y H RLIPNV V S YE - NF T 557
Name
Accession
Description
Interval
E-value
G_glu_transpept
pfam01019 Gamma-glutamyltranspeptidase;
58-544
0e+00
Gamma-glutamyltranspeptidase;
Pssm-ID: 425991
Cd Length: 499
Bit Score: 541.80
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 58 RA IL QQQ G SP VDA TI AA LV C TS VV N P Q S M G L GGG VIFT IY NVT TGKV E VI N ARET V PA SHAPSLL D QCAQALPLG TG AQW 137
Cdd:pfam01019 1 LD IL RKG G NA VDA AV AA AL C LG VV E P H S S G I GGG GFML IY DAK TGKV L VI D ARET A PA AATKDMF D GKGDSKLSL TG GLA 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 138 I GVPGE LR G Y AEAH R R H GRLPWA Q L FQ P T I A L L R G G HV V A P V L S R F L HNSIL R P s LQAST LR QL F FNGTEP L RPQDP L PW 217
Cdd:pfam01019 81 V GVPGE VA G L AEAH K R Y GRLPWA D L LE P A I K L A R D G FP V S P A L A R A L ARAEE R L - RADPG LR KI F LPTGRV L KAGEL L KQ 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 218 PALA T TLE TV A T EG VEV FY T G R L G Q M LV E D IAKE G SQL T LQ DLA KFQPEVVDA L EVPL G D YT L YSPPP PA GG AI L SF ILN 297
Cdd:pfam01019 160 PALA K TLE LI A E EG PDA FY R G E L A Q Q LV A D LQAN G GII T AE DLA NYRVKIREP L SADY G G YT V YSPPP SS GG IA L LQ ILN 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 298 V L R GF NF S TES marpe GRVNVY H H L V E TL K F A KGQ R W R - LGDP RSH P KLQ nas RD LL GETL A QLIRQQ I DGRGDHQL S H y 376
Cdd:pfam01019 240 I L E GF DL S SLL ----- NSAEYL H L L I E AM K L A YAD R T R y LGDP DFV P VPV --- EN LL SPEY A KERAKL I NPNAAFPS S Y - 310
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 377 slaea WGHGT GT S H V SV LGE DG S AV AA TSTIN TP FG AM V YS P R TGI I LNNE LL D LCERCPRGS G TT PSP DA vcsavsgdr 456
Cdd:pfam01019 311 ----- APEDG GT T H F SV VDR DG N AV SF TSTIN LG FG SG V VV P G TGI L LNNE MD D FSTPPGNAF G LD PSP AN --------- 376
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 457 vggapgrcw PPV PG E R SP SSM V P S I LINK a QGSK LV I G GA GG EL IISAV A Q A I MSK L W LG F DL RA A IA AP IL H VNSKGCV 536
Cdd:pfam01019 377 --------- AIA PG K R PL SSM A P T I VLDD - GKPV LV V G AP GG SR IISAV L Q V I VNV L D LG L DL QQ A VD AP RI H HQLPDVL 446
....*...
gi 2462584680 537 E Y EP N F SQ 544
Cdd:pfam01019 447 E V EP G F PE 454
Ggt
COG0405 Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
54-544
6.56e-100
Gamma-glutamyltranspeptidase [Amino acid transport and metabolism];
Pssm-ID: 440174
Cd Length: 507
Bit Score: 311.60
E-value: 6.56e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 54 S DI G RA IL QQQ G SP VDA TI AA LVCTS VV N P Q S M G L GGG VIFT IY NVTT GKV EVINA R E T V PA SHA P SLLDQCAQAL P l GT 133
Cdd:COG0405 10 S QA G LE IL RAG G NA VDA AV AA AAALA VV E P H S S G I GGG GFAL IY DAKD GKV TALDG R G T A PA AAT P DMYLDAGDEI P - VR 88
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 134 G AQWI GVPG ELR G YAE AH R R H G R LP W A Q L FQ P T I A L LRG G HV V A P V L SRF L HNS il RPS L QAS - TLRQL F FNGTE P LRPQ 212
Cdd:COG0405 89 G PLAV GVPG TVA G WEA AH E R Y G T LP L A E L LA P A I R L AED G FP V S P R L AAL L AAA -- AER L ARD p GAAAI F LPDGR P PKAG 166
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 213 D P L PW P A LA T TL ETV A T EG VEV FY T G RLGQML V EDIAKE G SQ LTL Q DLA KFQP E VVDA L EVPLGD YT L YS P PPP AG G AI L 292
Cdd:COG0405 167 D I L RQ P D LA A TL RRI A E EG ADA FY R G EIAEAI V AAVQAA G GL LTL E DLA AYRA E WREP L SGTYRG YT V YS M PPP SQ G IA L 246
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 293 SF ILN V L R GF NFSTESMARP E G rvnv Y H H L V E TL K -- FA KGQ R W r LGDP RSHP klq NASRD LL GETL A QLIRQQ ID GRGD 370
Cdd:COG0405 247 LQ ILN I L E GF DLAALGPDSA E Y ---- V H L L A E AM K la FA DRD R Y - LGDP DFVD --- VPVEG LL SPAY A AERAAL ID PDRA 318
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 371 HQLSHYSLAEAWGH G t G T S H V SV LGE DG S AV AA T ST I NTP FG AM V YS P R TG II LNN elldlcercp RG SGTTPS P davcs 450
Cdd:COG0405 319 TPSPRPGDPTGPES G - D T T H L SV VDR DG N AV SL T QS I YGG FG SG V VV P G TG FL LNN ---------- RG DDFSLD P ----- 382
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 451 avsgdrvg G A P GR cwp PV PG E R SP S S M V P S I LI n K AQGSK LV I G GA GG EL I ISA V A Q AIMSK L WL G FDLRA A IA AP - IL H 529
Cdd:COG0405 383 -------- G H P NA --- LA PG K R PR S T M S P T I VL - K DGKPV LV F G SP GG SR I PQT V L Q VLLNV L DF G MNPQE A VD AP r WH H 450
490
....*....|....*
gi 2462584680 530 VNSKGCV E Y EP N F SQ 544
Cdd:COG0405 451 QGLPDTL E L EP R F PP 465
g_glut_trans
TIGR00066 gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of ...
54-543
6.63e-83
gamma-glutamyltranspeptidase; Also called gamma-glutamyltranspeptidase (ggt). Some members of this family have antibiotic synthesis or resistance activities. In the case of a cephalosporin acylase from Pseudomonas sp., the enzyme was shown to retain some gamma-glutamyltranspeptidase activity. Other, more distantly related proteins have ggt-related activities and score below the trusted cutoff. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs]
Pssm-ID: 129176
Cd Length: 516
Bit Score: 267.79
E-value: 6.63e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 54 S D IG RA IL QQQ G SPV DA TI A ALVCTS VV N P QSM GLGGG VIFT I YNVT T GKVEV I NA RE TV PA - SHAPSL LD QCAQA LP LG 132
Cdd:TIGR00066 11 S E IG ED IL KEG G NAF DA AV A VGLALA VV E P FMT GLGGG GFML I SGKK T KDTTA I DF RE RA PA k ATRDMF LD KSGNP LP GK 90
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 133 -- TG AQW IGVPG ELR G YAE A HRRH G R LP WAQ L FQ P T I A L L R G G HVVAPV L SRF L HNSILRPSLQASTLRQL F FNGTE PL R 210
Cdd:TIGR00066 91 sl TG GLA IGVPG TVA G LEA A LKKY G T LP LKD L IE P A I K L A R N G FPINEA L ADT L ELYEEVLLTTKEDSKDI F NPTGK PL K 170
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 211 PQ D P L PWPA LA TT LE TV A TE G VEV FY T G RLGQMLVEDIA K E G SQL T LQ DLA KFQP E V vdal EV PL - GDY TL Y S ---- PPP 285
Cdd:TIGR00066 171 EG D T L VQKD LA KS LE LI A EN G PDA FY K G DIAESIIDTLQ K N G GIM T KK DLA AYDV E I ---- RK PL s GDY RG Y Q vytt PPP 246
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 286 PA GG AI L SFI LN V L RG F NF S tesm ARPE G RVNV Y HH L V E TL K FAKGQ R W R - LGDP RSHPK lqn ASRD LL GETL A QLIR Q Q 364
Cdd:TIGR00066 247 SS GG IH L LQA LN I L EN F DL S ---- QYGD G SAET Y QL L A E AM K LSYAD R S R y LGDP EFVDV --- PLEE LL DKRY A KELA Q S 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 365 I D - GRG D HQLSH Y SL A EAWGH G TG T S H V SV LGE DG S AV AA T S TIN TP FG AM V YS P R TGI I LNNE LL D LCER cprgsgttp 443
Cdd:TIGR00066 320 I K i NKV D PKSTI Y PG A YQPNE G SQ T T H F SV VDR DG N AV SL T T TIN LE FG SG V HA P D TGI L LNNE MD D FSLK --------- 390
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 444 spdavcsavsgdrvgga PG RCWPPV P GE R SP SSM V P S I LINKAQ g SK LV I G GA GG EL II SA V A Q A I MSKLWL G FD L RA A I 523
Cdd:TIGR00066 391 ----------------- PG GANAVE P NK R PL SSM A P T I VLKDGK - PD LV V G SP GG SR II TT V L Q T I VRHIDY G MP L AE A V 452
490 500
....*....|....*....|.
gi 2462584680 524 AA P IL H VNS - KGCVEY E PN F S 543
Cdd:TIGR00066 453 SE P RI H HQW l PDELRL E KG F P 473
PLN02180
PLN02180 gamma-glutamyl transpeptidase 4
49-543
1.65e-73
gamma-glutamyl transpeptidase 4
Pssm-ID: 177836
Cd Length: 639
Bit Score: 246.51
E-value: 1.65e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 49 D SKV CS D IG RAI L QQQ G SP VDA TI A ALV C TS VVNP Q S M G L GGG VIFTIYNVTTG K V E VINA RET V P ASHAPSLLDQC A Q A 128
Cdd:PLN02180 88 D DAR CS E IG ASV L RRG G HA VDA AV A ITL C IG VVNP M S S G I GGG SFLIVSSQKDS K A E AFDM RET A P LAASKDMYKND A S A 167
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 129 LP LG tg A QWI GVPGE LR G YA EA HR R H GRLPW AQ LF Q P T I A L L R G G H VV A P V L SRFLHNSILR p S L QAST LR QL F FNGTEP 208
Cdd:PLN02180 168 KS LG -- A LSM GVPGE IA G LY EA WK R Y GRLPW KP LF E P A I E L A R D G F VV H P Y L GKAISSHAAM - I L KDPG LR SV F SRNGQV 244
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 209 L R P QDPLPW P A LA TT LET VATE G VEV FY T G RL G QM LV E D IA K E G SQL T LQ DL AKFQPE V V DA LE V PLGD YT LYSP PPP A G 288
Cdd:PLN02180 245 L K P GETCYN P E LA QS LET ISEQ G PGA FY N G TI G EK LV K D VK K A G GII T MD DL RSYEVL V T DA MS V DVMG YT IHGM PPP S G 324
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 289 G AI - L S FILNV L RGF - N FS T E S marpe GR VNVY H H L V E TL K FAKGQ R WR LGDP r SHPKLQ NA SRDL L GETL A QL I RQQ I D 366
Cdd:PLN02180 325 G TL g F S MVIDI L DSY s N LY T A S ----- GR ELGL H R L I E AM K HMFAA R MD LGDP - EFVNIT NA MNQM L SKAH A EE I QKR I F 398
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 367 GRGDHQLSH Y SLAEAWGHGT GTSH VSVLGE D GSA V AA TST I N TP FGA M V Y SP R TGI I LNNE LL D L cercprgsg T TP spd 446
Cdd:PLN02180 399 DNTTFPPEY Y LNRWSQLRDQ GTSH FCIVDA D RNS V SM TST V N YG FGA G V L SP S TGI V LNNE MD D F --------- S TP --- 466
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 447 avc SAVSG D RVGG AP GRCWP pv P GE R SP SSM V P s IL I N K AQGSKLVI GGAGG EL II S AV A Q AIMSKLW L GFDLRA A I - A A 525
Cdd:PLN02180 467 --- AEITP D MLPP AP TNFIE -- P NK R PL SSM T P - LV I T K DGEFVAAL GGAGG MH II P AV L Q VFLNCFV L NMKPKE A V e S A 540
490
....*....|....*...
gi 2462584680 526 P I L H VNSKGC V E YE p NF S 543
Cdd:PLN02180 541 R I Y H RLIPNV V S YE - NF T 557
PLN02198
PLN02198 glutathione gamma-glutamylcysteinyltransferase
49-539
1.61e-71
glutathione gamma-glutamylcysteinyltransferase
Pssm-ID: 177849
Cd Length: 573
Bit Score: 239.59
E-value: 1.61e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 49 D SKV CS D IG RAI L QQQ G SPV DA TI AA LV C TS VV N P Q S M G L GGG V i FT IYNVTT G KVEVINA RET V P A S HAPSLLD qc AQA 128
Cdd:PLN02198 39 D DGR CS V IG MNV L REG G NAI DA SV AA AL C LG VV S P A S S G I GGG A - FT LIKLAN G EEIAYDS RET A P L S ATENMYG -- GNV 115
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 129 LPLGT GA QWI GVPGE LR G YAE A HRR HG R LPW AQ L FQ P TIA L LRG G HVVAPV L s RFLH N SILRPS L QAST L RQ LF FNGT E P 208
Cdd:PLN02198 116 ELKKK GA LSV GVPGE VA G LFT A WKQ HG K LPW KR L VR P AEK L AAE G FKISKY L - YMQM N ATRSDI L ADKG L SD LF VSNG E L 194
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 209 LR P QDPLPW P A LA T TL ETVATE G VEV FY T G RL G QM LV E DI A K E G SQL TL Q DL AKFQPE V VDA L EVP - LG DYT L YS PPP PA 287
Cdd:PLN02198 195 KK P GTICHN P K LA L TL RLIGEY G PKA FY N G TV G VN LV R DI Q K S G GII TL K DL QSYRVK V KEP L SAD i LG YRV L GM PPP SS 274
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 288 GGA ILSF ILN V L RGFNFS t ESMAR P E G rvnv Y H H L V E T LK F A KGQ R WR LGDP r SHPKLQNASR D L L GETL AQ LIRQQ I DG 367
Cdd:PLN02198 275 GGA AMML ILN I L AQYGIP - SGVSG P L G ---- V H R L I E A LK H A FAV R MN LGDP - DFVDVTKVVS D M L SPKF AQ DLKSK I ND 348
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 368 RGDHQLS HY sl AEA W G -- HGT GTSH V S VLGEDGS AV AA TSTIN TP FGA MVY SP R TGI I LNNE LL D LCERCPR G SGTTPS P 445
Cdd:PLN02198 349 NKTFDPK HY -- GGR W N qi DDH GTSH L S IIDSERN AV SM TSTIN GY FGA LML SP S TGI V LNNE MD D FSIPMKS G GNLDVP P 426
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 446 D A VCSAVS gdrvggapgrcwppv PG E R SP SSM V P S I LI n K AQGS K LVI G GA GG EL II SAVAQAIMSKLW L GF D LRAAIA A 525
Cdd:PLN02198 427 P A PANFIR --------------- PG K R PL SSM T P T I VL - K DGKV K AAV G AS GG AN II AGTTEVYLNHFF L KM D PLSSVL A 490
490
....*....|....*
gi 2462584680 526 P - I L H VNSKGCVE YE 539
Cdd:PLN02198 491 P r I Y H QLIPNRAS YE 505
ggt
PRK09615 gamma-glutamyltranspeptidase; Reviewed
56-529
1.05e-50
gamma-glutamyltranspeptidase; Reviewed
Pssm-ID: 181992
Cd Length: 581
Bit Score: 183.57
E-value: 1.05e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 56 I G RA IL Q Q Q G SP VDA TI A ALVCTS V VN PQ SMG LGGG V i F TIYNVTT G KVEV I NA RE TV PA SHAPSL - LD qc A Q AL P LG -- 132
Cdd:PRK09615 62 V G VD IL K Q G G NA VDA AV A VGYALA V TH PQ AGN LGGG G - F MLLRTKN G NTTA I DF RE MA PA KATRDM f LD -- D Q GN P DS kk 138
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 133 -- T GAQWI G V PG ELR G YAE A HRRH G RL P WAQLF QP TIA L L R G G HV V APV L SRF L HNSILRPSLQASTLRQL F FNGT EPL R 210
Cdd:PRK09615 139 sl T SHLAS G T PG TVA G FSL A LDKY G TM P LNKVV QP AFK L A R D G FI V NDA L ADD L KTYGSEVLPNHENSKAI F WKEG EPL K 218
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 211 PQ D P L PWPA LA TT LE TV A TE G VEV FY T G RLGQMLVEDIA K E G SQL T LQ DLA KFQ pevvd A L E - V P LG ---- D Y TL YS P PP 285
Cdd:PRK09615 219 KG D K L VQAN LA KS LE MI A EN G PDA FY K G TIADQIAQEMQ K N G GLI T KE DLA AYK ----- A V E r T P IS gdyr G Y QV YS M PP 293
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 286 P AG G A I - LSF ILN V L RG F NFSTESM arpe G RVNVYHHLV E TL K F A KGQ R WR - LGDP RS hpk LQNASRD L LGETL A QL I RQ 363
Cdd:PRK09615 294 P SS G G I h IVQ ILN I L EN F DMKKYGF ---- G SADAMQIMA E AE K Y A YAD R SE y LGDP DF --- VKVPWQA L TNKAY A KS I AD 366
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 364 QID --- GRGDHQLSHYS LA EA wg HGTG T S H V SV LGE DG S AVA A T S T I NT P FG AMVYSPRT GI I LNN ELL D LCER cprgsg 440
Cdd:PRK09615 367 QID ink AKPSSEIRPGK LA PY -- ESNQ T T H F SV VDK DG N AVA V T Y T L NT T FG TGIVAGNS GI L LNN QMD D FSAK ------ 438
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2462584680 441 tt P SPDA V CSA V S GD rv GG A P G rcwppv P GE R SP SSM V P S I LI n K AQGSK LV I G GA GG EL II SA V A Q AIMSKLWL G FDLR 520
Cdd:PRK09615 439 -- P GVPN V YGL V G GD -- AN A V G ------ P NK R PL SSM S P T I VV - K DGKTW LV T G SP GG SR II TT V L Q MVVNSIDY G MNVA 507
....*....
gi 2462584680 521 A A IA AP IL H 529
Cdd:PRK09615 508 E A TN AP RF H 516
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
