|
Name |
Accession |
Description |
Interval |
E-value |
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
80-436 |
3.29e-12 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 70.48 E-value: 3.29e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 80 ELSALIEEKCKLLDKVSIVQK---EYEGLESSLKEASFEKESTEAQSLEATYENLEQSKSKLEDEILLLEEKLEEERAKH 156
Cdd:TIGR02169 188 RLDLIIDEKRQQLERLRREREkaeRYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRL 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 157 SEQDELMADISKRIQSL-EDESKSLKSQVAEakttfriFEINEERLKGAIKDALNENSQLQESQKQLLQETEMMKEQVND 235
Cdd:TIGR02169 268 EEIEQLLEELNKKIKDLgEEEQLRVKEKIGE-------LEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEE 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 236 LDKQKVALEESRAQAEQALSEKESQIETLVtsllkmkdwaAVLGEADdgnldldmksglENTAALDNQPKGALKKLiyaA 315
Cdd:TIGR02169 341 LEREIEEERKRRDKLTEEYAELKEELEDLR----------AELEEVD------------KEFAETRDELKDYREKL---E 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 316 KLNASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASLQSEKTEFESESQKLQQKLKVITELYQENEMKLHRkl 395
Cdd:TIGR02169 396 KLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYD-- 473
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 1720372421 396 tveenyrleKEEKLSKVDEKISHATEELETCRQRAKDLEEE 436
Cdd:TIGR02169 474 ---------LKEEYDRVEKELSKLQRELAEAEAQARASEER 505
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
161-437 |
3.47e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 70.47 E-value: 3.47e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 161 ELMADISKRIQSLEDESKSLKSQVAEAKTTfrifeinEERLKGAIKDALNENSQLQESQKQLLQETEMMKEQVNDLDKQK 240
Cdd:TIGR02168 691 EKIAELEKALAELRKELEELEEELEQLRKE-------LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 241 VALEESRAQAEQALSEKESQIETLVTSLLKMKDWAAVLGEADDgnlDLDMKSGLENTAALDNQPKgalkkliyaaklnas 320
Cdd:TIGR02168 764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALD---ELRAELTLLNEEAANLRER--------------- 825
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 321 LKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASLQSEKTEFESESQKLQQKLKVITE---LYQENEMKLHRKLTV 397
Cdd:TIGR02168 826 LESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEalaLLRSELEELSEELRE 905
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 1720372421 398 EENYRLEKEEKLSKVDEKISHATEELETCRQRAKDLEEEL 437
Cdd:TIGR02168 906 LESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
63-426 |
8.72e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 68.93 E-value: 8.72e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 63 RSIRSRFYVGREKKLALELSAL-IEEKcklldkvsivQKEYEGLESSLKEASFEKESTEAQsLEATYENLEQsksklede 141
Cdd:TIGR02168 211 KAERYKELKAELRELELALLVLrLEEL----------REELEELQEELKEAEEELEELTAE-LQELEEKLEE-------- 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 142 illleekleeERAKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKTTFRIFEINEERLKGAIKDALNENSQLQESQKQ 221
Cdd:TIGR02168 272 ----------LRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAE 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 222 LLQETEMMKEQVNDLDKQKVALEESRAQAEQALSEKESQIETLVTSLLKMKDWAAVLgEADDGNLDLDMKSGLENTAALD 301
Cdd:TIGR02168 342 LEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL-NNEIERLEARLERLEDRRERLQ 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 302 NQPKGALKKLiyaakLNASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASLQSEKTEFESESQKLQQKLKVIT 381
Cdd:TIGR02168 421 QEIEELLKKL-----EEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE 495
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 1720372421 382 ELyQENEMKLHRKLTVEENYRLEKEEKLSKVDEKIShATEELETC 426
Cdd:TIGR02168 496 RL-QENLEGFSEGVKALLKNQSGLSGILGVLSELIS-VDEGYEAA 538
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
75-441 |
1.34e-11 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 68.12 E-value: 1.34e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 75 KKLALELSALIEEKCKLLDK-----VSIVQKEYEGLESSLK--EASFEKESTEAQSLEATYENLEQSKSKledeilllee 147
Cdd:TIGR04523 291 NQLKSEISDLNNQKEQDWNKelkseLKNQEKKLEEIQNQISqnNKIISQLNEQISQLKKELTNSESENSE---------- 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 148 KLEEERAKHSEqdelMADISKRIQSLEDESKSLKSQVAEAKTTFRIFEINEERLKGAIKDALNENSQLQESQKQLLQETE 227
Cdd:TIGR04523 361 KQRELEEKQNE----IEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETII 436
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 228 MMKEQVNDLDKQKVALEESRAQAEQALSEKESQIETLVTSLLKMK-DWAAVLGEADDGNLDLDMKSglENTAALDNQPKg 306
Cdd:TIGR04523 437 KNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKqNLEQKQKELKSKEKELKKLN--EEKKELEEKVK- 513
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 307 ALKKLIyaAKLNASLKALEGERNQVYTQLS----EVDQVKEDLT------------EHIKSLESKQASLQSEKTEFEses 370
Cdd:TIGR04523 514 DLTKKI--SSLKEKIEKLESEKKEKESKISdledELNKDDFELKkenlekeideknKEIEELKQTQKSLKKKQEEKQ--- 588
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720372421 371 QKLQQKLKVITELYQENEMKLHRKLTVEENYRLEKEE--KLSKVDEKISHATEELEtcrQRAKDLEEELERTI 441
Cdd:TIGR04523 589 ELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKEneKLSSIIKNIKSKKNKLK---QEVKQIKETIKEIR 658
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
70-495 |
6.67e-11 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 65.81 E-value: 6.67e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 70 YVGREKKLALELSALIEEKCKLLDKVSIVQKEYEGLESSLKEASFEKESTEAQS------LEATYENLEQSKSKLEDEIL 143
Cdd:TIGR04523 209 KIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQnkikkqLSEKQKELEQNNKKIKELEK 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 144 LLEEKLEEERA-KHSEQDELMADISKRIQSLEDESKSLKSQVAEAKTTfrIFEINEE--RLKGAIKDALNENS----QLQ 216
Cdd:TIGR04523 289 QLNQLKSEISDlNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKI--ISQLNEQisQLKKELTNSESENSekqrELE 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 217 ESQKQL----------LQETEMMKEQVNDL-------DKQKVALEESRAQAEQALSEKESQIETLVTSLLKMKDWAAVLg 279
Cdd:TIGR04523 367 EKQNEIeklkkenqsyKQEIKNLESQINDLeskiqnqEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDL- 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 280 EADDGNLDLDMKSgLENTAALDNQPKGALKKLIYAAKLNasLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASL 359
Cdd:TIGR04523 446 TNQDSVKELIIKN-LDNTRESLETQLKVLSRSINKIKQN--LEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSL 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 360 QSEKTEFESESQKLQQKLKVItelyqENEMKlhrKLTVEENYRLEKEEKLSKvDEKIS---HATEELETCRQRAKDLEEE 436
Cdd:TIGR04523 523 KEKIEKLESEKKEKESKISDL-----EDELN---KDDFELKKENLEKEIDEK-NKEIEelkQTQKSLKKKQEEKQELIDQ 593
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 1720372421 437 LERTIHSYQGQVISHEKKAhdnwlaaRTLERNLNDLRKENAHNRQKLTETEFKFELLEK 495
Cdd:TIGR04523 594 KEKEKKDLIKEIEEKEKKI-------SSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQ 645
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
165-495 |
6.73e-11 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 65.81 E-value: 6.73e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 165 DISKRIQSLEDESKSLKSQVAEAKTTfrIFEINEERLKGAIKdaLNENSQLQESQKQLLQETEMMKEQVNDLDKQKVALE 244
Cdd:TIGR04523 163 DLKKQKEELENELNLLEKEKLNIQKN--IDKIKNKLLKLELL--LSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQ 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 245 ESRAQAEQALSEKESQIETLVTSLLKMKDwaavlgEADDGNLDLDMKSG-LENTAALDNQPKGALKKL------IYAAKL 317
Cdd:TIGR04523 239 QEINEKTTEISNTQTQLNQLKDEQNKIKK------QLSEKQKELEQNNKkIKELEKQLNQLKSEISDLnnqkeqDWNKEL 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 318 NASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASLQSEKTEFESESQKLQQKLKVITElyqENEMKLhrkltv 397
Cdd:TIGR04523 313 KSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKK---ENQSYK------ 383
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 398 EENYRLEKEeklskvdekishaTEELETCRQRAKDLEEELERTIHSYQGQVISHEKKaHDNWLAARTLERN-LNDLRKEN 476
Cdd:TIGR04523 384 QEIKNLESQ-------------INDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKE-IERLKETIIKNNSeIKDLTNQD 449
|
330
....*....|....*....
gi 1720372421 477 AHNRQKLTETEFKFELLEK 495
Cdd:TIGR04523 450 SVKELIIKNLDNTRESLET 468
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
199-441 |
3.65e-10 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 62.47 E-value: 3.65e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 199 ERLKGAIKDALNENSQLQESQKQLLQETEMMKEQVNDLDKQKVALEESRAQAEQALSEKESQIETLVTSLLKMKDWAAVL 278
Cdd:COG4942 30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEL 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 279 geaddgnLDLDMKSGLENTAAL---DNQPKGALKKLIYAAKLNASLKAlegernqvytQLSEVDQVKEDLTEHIKSLESK 355
Cdd:COG4942 110 -------LRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARRE----------QAEELRADLAELAALRAELEAE 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 356 QASLQSEKTEFESESQKLQQKLKvitelyqenemklhrkltveenyrlEKEEKLSKVDEKISHATEELETCRQRAKDLEE 435
Cdd:COG4942 173 RAELEALLAELEEERAALEALKA-------------------------ERQKLLARLEKELAELAAELAELQQEAEELEA 227
|
....*.
gi 1720372421 436 ELERTI 441
Cdd:COG4942 228 LIARLE 233
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
67-439 |
3.93e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.54 E-value: 3.93e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 67 SRFYVGRE-KKLALELSALIEEKCKLLDKVSIVQKEYEGLESSLKEASFEKESTEAQS--LEATYENLEQSKSKLEDEIL 143
Cdd:TIGR02168 671 SILERRREiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQIsaLRKDLARLEAEVEQLEERIA 750
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 144 LLEEKLEEERAKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKTTFrifEINEERLkgaikDALN-ENSQLQESQKQL 222
Cdd:TIGR02168 751 QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEEL---KALREAL-----DELRaELTLLNEEAANL 822
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 223 LQETEMMKEQVNDLDKQKVALEESRAQAEQALSEKESQIETLVTSLlkmkdwaavlgeaddgnldldmksglentaaldn 302
Cdd:TIGR02168 823 RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELI---------------------------------- 868
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 303 qpkgalkkliyaAKLNASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKqaslqseKTEFESESQKLQQKLKVITE 382
Cdd:TIGR02168 869 ------------EELESELEALLNERASLEEALALLRSELEELSEELRELESK-------RSELRRELEELREKLAQLEL 929
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 1720372421 383 LYQENEMKLHRKL-TVEENYRLEKEEklskVDEKISHATEELETCRQRAKDLEEELER 439
Cdd:TIGR02168 930 RLEGLEVRIDNLQeRLSEEYSLTLEE----AEALENKIEDDEEEARRRLKRLENKIKE 983
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
153-483 |
6.07e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.15 E-value: 6.07e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 153 RAKHSEQDELMADIS-KRIQSLEDESKSLKSQVAEAKTTFRIFEINEERLKGAIKDALNENSQLQESQKQLLQETEMMKE 231
Cdd:TIGR02168 216 KELKAELRELELALLvLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 232 QVNDLDKQKVALEESRAQAEQALSEKESQIETLVTSLLKMKdwaavlgeaddgnldldmksglENTAALDNQPKGALKKL 311
Cdd:TIGR02168 296 EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELA----------------------EELAELEEKLEELKEEL 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 312 iyaAKLNASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASLQSEKTEFESESQKLQQKLKVITELYQENEMKL 391
Cdd:TIGR02168 354 ---ESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKL 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 392 hrkltvEENYRLEKEEKLSKVDEKISHATEELETCRQRAKDLE---EELERTIHSYQGQVISHEKKAHdnwlAARTLERN 468
Cdd:TIGR02168 431 ------EEAELKELQAELEELEEELEELQEELERLEEALEELReelEEAEQALDAAERELAQLQARLD----SLERLQEN 500
|
330
....*....|....*...
gi 1720372421 469 LNDLR---KENAHNRQKL 483
Cdd:TIGR02168 501 LEGFSegvKALLKNQSGL 518
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
199-388 |
3.70e-09 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 59.46 E-value: 3.70e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 199 ERLKGAIKDALNENSQLQESQKQLLQETEMMKEQVNDLDKQKVALEESRAQAEQALSEKESQIETLVTsllKMKDWAAVL 278
Cdd:COG3883 19 QAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERRE---ELGERARAL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 279 GEADDGNLDLDMKSGLENTA-ALDNQpkGALKKLiyAAKLNASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQA 357
Cdd:COG3883 96 YRSGGSVSYLDVLLGSESFSdFLDRL--SALSKI--ADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKA 171
|
170 180 190
....*....|....*....|....*....|.
gi 1720372421 358 SLQSEKTEFESESQKLQQKLKVITELYQENE 388
Cdd:COG3883 172 ELEAQQAEQEALLAQLSAEEAAAEAQLAELE 202
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
66-474 |
5.85e-09 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 59.99 E-value: 5.85e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 66 RSRFYVGREKKLAlelsALIEEKCKLLDKVSIVQKEYEGLESSLKEASFEKESTEAQSLEATYENLEQSKSKLEDEILLL 145
Cdd:pfam02463 164 GSRLKRKKKEALK----KLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERI 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 146 EEKLEEERAKHSEQDELMADISKRIQSLED-------ESKSLKSQVAEAKTTFRIFEINEERLKGAIKDALNENSQLQES 218
Cdd:pfam02463 240 DLLQELLRDEQEEIESSKQEIEKEEEKLAQvlkenkeEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKES 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 219 QKQLLQETEMMKEQVNDLDKQKVALEESRAQAEQALSEKESQIETLVTSLLKMKDWAAVLGEADDGNLDLDmkSGLENTA 298
Cdd:pfam02463 320 EKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAA--KLKEEEL 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 299 ALDNQPKGALKKLIYAAKLNASLkaLEGERNQVYTQLSEVDQVKEDLTEHI---KSLESKQASLQSEKTEFESESQKLQQ 375
Cdd:pfam02463 398 ELKSEEEKEAQLLLELARQLEDL--LKEEKKEELEILEEEEESIELKQGKLteeKEELEKQELKLLKDELELKKSEDLLK 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 376 KLKVITELYQENEMKLHRKLTVEENYRLEKEEKLSKVD-EKISHATEELETCRQRAKDLEEELERTIHSYQGQVISHEKK 454
Cdd:pfam02463 476 ETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLaLIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSA 555
|
410 420
....*....|....*....|
gi 1720372421 455 AHDNWLAARTLERNLNDLRK 474
Cdd:pfam02463 556 TADEVEERQKLVRALTELPL 575
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
73-354 |
8.64e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 59.30 E-value: 8.64e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 73 REKKLALELSALIEEKCKLLDKVSIVQKEYEGLESSLKEASFEKESTEAQsLEATYENLEQSKSKLEDEILLLEEKLEEE 152
Cdd:TIGR02168 741 EVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ-IEQLKEELKALREALDELRAELTLLNEEA 819
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 153 RAKHSEQDEL---MADISKRIQSLEDESKSLKSQVAEAKTTFRIFEINEERLKGAIKDALNENSQLQESQKQLLQETEMM 229
Cdd:TIGR02168 820 ANLRERLESLerrIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEEL 899
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 230 KEQVNDLDKQKVALE-------ESRAQAEQALSEKESQIETLVTSLlkmkdwaavlgeADDGNLDLDMKsgLENTAALDN 302
Cdd:TIGR02168 900 SEELRELESKRSELRreleelrEKLAQLELRLEGLEVRIDNLQERL------------SEEYSLTLEEA--EALENKIED 965
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 303 QPKGALKKLIyaaKLNASLKALeGERN--------QVYTQLSEVDQVKEDLTEHIKSLES 354
Cdd:TIGR02168 966 DEEEARRRLK---RLENKIKEL-GPVNlaaieeyeELKERYDFLTAQKEDLTEAKETLEE 1021
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
74-496 |
3.11e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 57.84 E-value: 3.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 74 EKKLALELSALIEEKCKLLDKVSIVQKEYEGLESSLKEASFEKESTEAQSLEATYENLEQSKSKLEDEILLLEEKLEEER 153
Cdd:PTZ00121 1389 EKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEE 1468
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 154 AKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKTTFRIFEINEERLKGAIKDALNENSQLQESQKqllQETEMMKEQV 233
Cdd:PTZ00121 1469 AKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKK---ADEAKKAEEK 1545
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 234 NDLDKQKVALEESRAQAEQALSEKESQIETLVTSLLKmkdwAAVLGEADDGNLDLDMKSGLENTAALDNQPKGALKKLIY 313
Cdd:PTZ00121 1546 KKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRK----AEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIK 1621
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 314 AAKlnasLKALEGERNQvytqlseVDQVKEDLTEHIKSLESKQASLQSEKTEFESESQKLQQKLKVITELYQENEMKlhR 393
Cdd:PTZ00121 1622 AEE----LKKAEEEKKK-------VEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE--K 1688
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 394 KltVEENYRLEKEEKlSKVDEKISHATEELETCRQRAKdleEELERTIHSYQGQVISHEKKAHDNWLAARTLERN----L 469
Cdd:PTZ00121 1689 K--AAEALKKEAEEA-KKAEELKKKEAEEKKKAEELKK---AEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKkiahL 1762
|
410 420
....*....|....*....|....*..
gi 1720372421 470 NDLRKENAHNRQKLTETEFKFELLEKD 496
Cdd:PTZ00121 1763 KKEEEKKAEEIRKEKEAVIEEELDEED 1789
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
89-475 |
3.57e-08 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 57.04 E-value: 3.57e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 89 CKLLDKVSIVQKEYEGLESSLKEASFE--KESTEAQSLEATYENLEQSKSKLEDEILLLEEKLEEERAKHSEQDELMA-- 164
Cdd:pfam05483 359 CSLEELLRTEQQRLEKNEDQLKIITMElqKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGke 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 165 -DISKRIQSLEDESKSLKSQVAEAKTTFRIFEINEERLKGAIKDALNENSQLQESQKQLLQETEMMKEQVND----LDKQ 239
Cdd:pfam05483 439 qELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDmtleLKKH 518
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 240 KVALEESRAQAEQALSekesQIETLVTSLLKMKDwaavlgEADDGNLDLDMKsGLENTAALDNQPKGALKKLIYAAKLNA 319
Cdd:pfam05483 519 QEDIINCKKQEERMLK----QIENLEEKEMNLRD------ELESVREEFIQK-GDEVKCKLDKSEENARSIEYEVLKKEK 587
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 320 SLKALEGERNQVYTQLSEVDQVKEDLTEHIKSL------ESKQAS---LQSEKTEFESESQKlqQKLKVITELYQEnemK 390
Cdd:pfam05483 588 QMKILENKCNNLKKQIENKNKNIEELHQENKALkkkgsaENKQLNayeIKVNKLELELASAK--QKFEEIIDNYQK---E 662
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 391 LHRKLTVEENYRLEKEEKLSKVDEKISHATEELETCRQRAKDLEEELERTIHSY-------QGQVISHEKKAHDNWLAAR 463
Cdd:pfam05483 663 IEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYdkiieerDSELGLYKNKEQEQSSAKA 742
|
410
....*....|..
gi 1720372421 464 TLERNLNDLRKE 475
Cdd:pfam05483 743 ALEIELSNIKAE 754
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
63-382 |
4.17e-08 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 57.37 E-value: 4.17e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 63 RSIRSRFYVGREKKLALELSALI--------EEKCKLLDKVSIVQKEYEGLESslkeasfekesTEAQSLEATYENLEQS 134
Cdd:TIGR01612 662 KSELSKIYEDDIDALYNELSSIVkenaidntEDKAKLDDLKSKIDKEYDKIQN-----------METATVELHLSNIENK 730
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 135 KSKLEdeillleekleeerakhseqdELMADISKRIQSleDESKSLKSQVAEakttfriFEINEERLKGAIKDALNENSQ 214
Cdd:TIGR01612 731 KNELL---------------------DIIVEIKKHIHG--EINKDLNKILED-------FKNKEKELSNKINDYAKEKDE 780
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 215 LQESQKQLLQETEMMKEQVNdLDKQKValEESRAQAEQA------LSEKESQIETLVTSLLKMKDwaAVLGEAD-----D 283
Cdd:TIGR01612 781 LNKYKSKISEIKNHYNDQIN-IDNIKD--EDAKQNYDKSkeyiktISIKEDEIFKIINEMKFMKD--DFLNKVDkfinfE 855
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 284 GNLDLDMKSGLENTAALDNQPKGAL--KKL-IYAAKLNAS-------LKALEGERNQVYTqLSEVD---QVKEDLTEHIK 350
Cdd:TIGR01612 856 NNCKEKIDSEHEQFAELTNKIKAEIsdDKLnDYEKKFNDSkslineiNKSIEEEYQNINT-LKKVDeyiKICENTKESIE 934
|
330 340 350
....*....|....*....|....*....|..
gi 1720372421 351 SLESKQASLQsektefesesQKLQQKLKVITE 382
Cdd:TIGR01612 935 KFHNKQNILK----------EILNKNIDTIKE 956
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
75-495 |
7.74e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 56.23 E-value: 7.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 75 KKLALELSALIEEKCKLL-------DKVSIVQKEYEGLESSLKEASFEKESTEAQ--SLEATYENLEQSKSKLEDEILLL 145
Cdd:PRK03918 168 GEVIKEIKRRIERLEKFIkrtenieELIKEKEKELEEVLREINEISSELPELREEleKLEKEVKELEELKEEIEELEKEL 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 146 EEKLEEER---AKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKTTFRIFEINEERLKGA--IKDALNENSQLQESQK 220
Cdd:PRK03918 248 ESLEGSKRkleEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELreIEKRLSRLEEEINGIE 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 221 QLLQETEMMKEQVNDLDKQKVALE------ESRAQAEQALSEKESQIETLVTSL--LKMKDWAAVLGEADdgnldldmKS 292
Cdd:PRK03918 328 ERIKELEEKEERLEELKKKLKELEkrleelEERHELYEEAKAKKEELERLKKRLtgLTPEKLEKELEELE--------KA 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 293 GLENTAALDN--QPKGALKKLIyaAKLNASLKALEGERNQVYTQLSEVDQvkEDLTEHIKSLESKQASLQSEKTEFESES 370
Cdd:PRK03918 400 KEEIEEEISKitARIGELKKEI--KELKKAIEELKKAKGKCPVCGRELTE--EHRKELLEEYTAELKRIEKELKEIEEKE 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 371 QKLQQKLKVItELYQENEMKLHRKLTVEENYRlEKEEKLSKVD-EKISHATEELETCRQRAKDLEEELERtihsyqgqVI 449
Cdd:PRK03918 476 RKLRKELREL-EKVLKKESELIKLKELAEQLK-ELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKGEIKS--------LK 545
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 1720372421 450 SHEKKAHDNWLAARTLERNLNDLRKENAHNRQKLTETEFK-FELLEK 495
Cdd:PRK03918 546 KELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFEsVEELEE 592
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
80-438 |
8.57e-08 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 55.82 E-value: 8.57e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 80 ELSALIEEKCKLLDKVSIVQKEYEGLESSLKEASFEKE--STEAQSLEATYENLEQSKSkledeillleekleeERAKHS 157
Cdd:PRK02224 238 EADEVLEEHEERREELETLEAEIEDLRETIAETEREREelAEEVRDLRERLEELEEERD---------------DLLAEA 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 158 EQDELMAD-ISKRIQSLEDESKSLKSQVAEAKTtfrifeineerlkgAIKDALNENSQLQESQKQLLQETEMMKEQVNDL 236
Cdd:PRK02224 303 GLDDADAEaVEARREELEDRDEELRDRLEECRV--------------AAQAHNEEAESLREDADDLEERAEELREEAAEL 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 237 DKQKVALEESRAQAEQALSEKESQIETLVTSLlkmKDWAAVLGEADDGNLDLdmksgLENTAALDNQpkgalkkliyAAK 316
Cdd:PRK02224 369 ESELEEAREAVEDRREEIEELEEEIEELRERF---GDAPVDLGNAEDFLEEL-----REERDELRER----------EAE 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 317 LNASLKALEGERNQVYT---------------------QLSEVDQVKEDLTEHIKSLESKQASLQS------EKTEFESE 369
Cdd:PRK02224 431 LEATLRTARERVEEAEAlleagkcpecgqpvegsphveTIEEDRERVEELEAELEDLEEEVEEVEErleraeDLVEAEDR 510
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720372421 370 SQKLQQKLKVITELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHAT---EELETCRQRAKDLEEELE 438
Cdd:PRK02224 511 IERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAeaeEEAEEAREEVAELNSKLA 582
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
78-377 |
1.51e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 55.33 E-value: 1.51e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 78 ALELSALIEEK--CKLLDKVSIVQKEYEGLESSLKEASFEKESTEAQ--SLEATYENLEQSkskledeillleekLEEER 153
Cdd:COG1196 215 YRELKEELKELeaELLLLKLRELEAELEELEAELEELEAELEELEAElaELEAELEELRLE--------------LEELE 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 154 AKHSEQDELMADISKRIQSLEDESKSLKSQVAEAkttfrifEINEERLKGAIKDALNENSQLQESQKQLLQETEMMKEQV 233
Cdd:COG1196 281 LELEEAQAEEYELLAELARLEQDIARLEERRREL-------EERLEELEEELAELEEELEELEEELEELEEELEEAEEEL 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 234 NDLDKQKVALEESRAQAEQALSEKESQIETLVTSLLKMKDwAAVLGEADDGNLDLDMKSGLENTAALDNQpkgalkkliy 313
Cdd:COG1196 354 EEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR-AAAELAAQLEELEEAEEALLERLERLEEE---------- 422
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720372421 314 AAKLNASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASLQSEKTEFESESQKLQQKL 377
Cdd:COG1196 423 LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
77-378 |
1.65e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 55.07 E-value: 1.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 77 LALELSALIEEKCKLLDKVSIVQKEYEGLESSLKEASFEKESTEAQ--SLEATYENLEQSKSklEDEILLLEEKLEEERA 154
Cdd:TIGR02169 728 LEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDlhKLEEALNDLEARLS--HSRIPEIQAELSKLEE 805
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 155 KHSEQDELMADISKRIQS-------LEDESKSLKSQVAEAKTTFRIFEINEERLKGAIKDALNENSQLQESQKQLLQETE 227
Cdd:TIGR02169 806 EVSRIEARLREIEQKLNRltlekeyLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLG 885
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 228 MMKEQVNDLDKQKVALEESRAQAEQALSEKESQIETLVTSLlkmkdwAAVLGEADDgnLDLDMKSGLENTAALDNQPKGA 307
Cdd:TIGR02169 886 DLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKL------EALEEELSE--IEDPKGEDEEIPEEELSLEDVQ 957
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720372421 308 LKKLiyaaKLNASLKALEGERNQVytqLSEVDQVKEDLTEhiksLESKQASLQSEKTEFESESQKLQQKLK 378
Cdd:TIGR02169 958 AELQ----RVEEEIRALEPVNMLA---IQEYEEVLKRLDE----LKEKRAKLEEERKAILERIEEYEKKKR 1017
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
77-496 |
3.03e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 54.00 E-value: 3.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 77 LALELSALIEEKCKLL----DKVSIVQKEYEGLESSLKEA-----SFEKESTEAQSLEATYENLEQSKSKLEDEILLLEE 147
Cdd:COG4717 44 RAMLLERLEKEADELFkpqgRKPELNLKELKELEEELKEAeekeeEYAELQEELEELEEELEELEAELEELREELEKLEK 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 148 KLeeeraKHSEQDELMADISKRIQSLEDESKSLKSQVAEakttfrifeinEERLKGAIKDALNENSQLQESQKQLLQET- 226
Cdd:COG4717 124 LL-----QLLPLYQELEALEAELAELPERLEELEERLEE-----------LRELEEELEELEAELAELQEELEELLEQLs 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 227 EMMKEQVNDLDKQKVALEESRAQAEQALSEKESQIETL---VTSLLKMKDWAAVLGEADDGNLDLDMKSGLENTAALDNQ 303
Cdd:COG4717 188 LATEEELQDLAEELEELQQRLAELEEELEEAQEELEELeeeLEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGS 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 304 PKGALKKLIYAAKLNASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASLQSEKTEFESESQK--LQQKLKVIT 381
Cdd:COG4717 268 LLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPeeLLELLDRIE 347
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 382 ELYQENE--MKLHRKLTVEEnYRLEKEEKLSKVDekishaTEELETCRQRAKDLEE--ELERTIHSYQGQVISHEKKAHD 457
Cdd:COG4717 348 ELQELLReaEELEEELQLEE-LEQEIAALLAEAG------VEDEEELRAALEQAEEyqELKEELEELEEQLEELLGELEE 420
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 1720372421 458 NWLAA---------RTLERNLNDLRKENAHNRQKLTETEFKFELLEKD 496
Cdd:COG4717 421 LLEALdeeeleeelEELEEELEELEEELEELREELAELEAELEQLEED 468
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
73-499 |
3.72e-07 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 53.96 E-value: 3.72e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 73 REKKLALELSALIEEKCKLLDKVSIvqkeyegLESSLKEASFEKESTEAQSleatyENLEQSKSKLEDEILLLEEKLEEE 152
Cdd:pfam05483 238 KEKQVSLLLIQITEKENKMKDLTFL-------LEESRDKANQLEEKTKLQD-----ENLKELIEKKDHLTKELEDIKMSL 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 153 RAKHSEQDELMADI---SKRIQSLEDESKSLKSQVAEAKTTFRIFEINEERLKGAIKDALNENSQLQESQKQLLQETEMm 229
Cdd:pfam05483 306 QRSMSTQKALEEDLqiaTKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITM- 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 230 keqvnDLDKQKVALEEsraqAEQALSEKESQIETLVTSLlkmkdwaavlgeADDGNLdLDMKSGLENTAaldNQPKGALK 309
Cdd:pfam05483 385 -----ELQKKSSELEE----MTKFKNNKEVELEELKKIL------------AEDEKL-LDEKKQFEKIA---EELKGKEQ 439
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 310 KLIYAaklnasLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASLQSEKTEFESESQKLQQKLKVITElyQENEM 389
Cdd:pfam05483 440 ELIFL------LQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQ--EASDM 511
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 390 KLHRKLTVEENYRLEKEE-----KLSKVDEKISHATEELETCRQRAKDLEEELERTIHSYQGQVISHEKKAHDNWLAART 464
Cdd:pfam05483 512 TLELKKHQEDIINCKKQEermlkQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKI 591
|
410 420 430
....*....|....*....|....*....|....*
gi 1720372421 465 LERNLNDLRKENAHNRQKLTETEFKFELLEKDPYA 499
Cdd:pfam05483 592 LENKCNNLKKQIENKNKNIEELHQENKALKKKGSA 626
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
76-495 |
5.56e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 53.14 E-value: 5.56e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 76 KLALELSALIEEKCKLLDKVSIVQKEYEGLESSLKE-ASFEKESTEAQSLEATYENLEQSKSKLEDEILLLEEKLEEERA 154
Cdd:PRK03918 242 ELEKELESLEGSKRKLEEKIRELEERIEELKKEIEElEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEE 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 155 KHSEQDELMADISK---RIQSLEDESKSLKSQVAEAKTTFRIFEineerlkgaikDALNENSQLQESQKQLLQET-EMMK 230
Cdd:PRK03918 322 EINGIEERIKELEEkeeRLEELKKKLKELEKRLEELEERHELYE-----------EAKAKKEELERLKKRLTGLTpEKLE 390
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 231 EQVNDLDKQKVALEESRAQAEQALSEKESQIETLVTSLLKMKDWAAV-------LGEADDGNL----DLDMKSGLENTAA 299
Cdd:PRK03918 391 KELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcgreLTEEHRKELleeyTAELKRIEKELKE 470
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 300 LDNQPKgalkkliyaaKLNASLKALEGERNQVYTQLSEvdqvkEDLTEHIKSLESKQASLQSEK-----TEFE---SESQ 371
Cdd:PRK03918 471 IEEKER----------KLRKELRELEKVLKKESELIKL-----KELAEQLKELEEKLKKYNLEElekkaEEYEklkEKLI 535
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 372 KLQQKLKVI-TELYQENEMKlhRKLTVEENYRLEKEEKLSKVDEKIshateeletcRQRAKDLEEELERTIHSYqgqvis 450
Cdd:PRK03918 536 KLKGEIKSLkKELEKLEELK--KKLAELEKKLDELEEELAELLKEL----------EELGFESVEELEERLKEL------ 597
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 1720372421 451 heKKAHDNWLAA-------RTLERNLNDLRKENAHNRQKLTETEFKFELLEK 495
Cdd:PRK03918 598 --EPFYNEYLELkdaekelEREEKELKKLEEELDKAFEELAETEKRLEELRK 647
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
72-438 |
6.94e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 53.14 E-value: 6.94e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 72 GREKKLALELSALiEEKCKLLDKVSIVQKEYEGLESSLKEASFEKesteaqsLEATYENLEQSKskledeillleeklee 151
Cdd:PRK03918 345 KKLKELEKRLEEL-EERHELYEEAKAKKEELERLKKRLTGLTPEK-------LEKELEELEKAK---------------- 400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 152 erakhseqDELMADISK---RIQSLEDESKSLKSQVAEAKTTFRIF-----EINEE-------RLKGAIKDALNENSQLQ 216
Cdd:PRK03918 401 --------EEIEEEISKitaRIGELKKEIKELKKAIEELKKAKGKCpvcgrELTEEhrkelleEYTAELKRIEKELKEIE 472
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 217 ESQKQL---LQETEMMKEQVNDLDKQKVALEESRAQAE-------QALSEKESQIETLVTSLLKMKdwaavlGEADDGNL 286
Cdd:PRK03918 473 EKERKLrkeLRELEKVLKKESELIKLKELAEQLKELEEklkkynlEELEKKAEEYEKLKEKLIKLK------GEIKSLKK 546
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 287 DLDMKSGLEntaaldnqpkgalKKLiyaAKLNASLKALEGERNQVYTQLSE-----VDQVKEDLTE-------------H 348
Cdd:PRK03918 547 ELEKLEELK-------------KKL---AELEKKLDELEEELAELLKELEElgfesVEELEERLKElepfyneylelkdA 610
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 349 IKSLESKQASLQSEKTEFESESQKLQQKLKVITELYQENEmKLHRKLTVEE-----NYRLEKEEKLSKVDEKISHATEEL 423
Cdd:PRK03918 611 EKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELE-ELEKKYSEEEyeelrEEYLELSRELAGLRAELEELEKRR 689
|
410
....*....|....*
gi 1720372421 424 ETCRQRAKDLEEELE 438
Cdd:PRK03918 690 EEIKKTLEKLKEELE 704
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
230-445 |
7.30e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.00 E-value: 7.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 230 KEQVNDLDKQKVALEESRAQAEQALSEKESQIETLVTSLLkmkDWAAVLGEADDgnlDLDMKSGLENTAALDNQpkgaLK 309
Cdd:COG4913 609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERRE---ALQRLAEYSWD---EIDVASAEREIAELEAE----LE 678
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 310 KLIyaaKLNASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASLQSEktefesesqklQQKLKVITELYQENEM 389
Cdd:COG4913 679 RLD---ASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEE-----------LDELQDRLEAAEDLAR 744
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1720372421 390 KLHRKLTVEENYRLEKEEKLSKVDEKIshaTEELETCRQRAKDLEEELERTIHSYQ 445
Cdd:COG4913 745 LELRALLEERFAAALGDAVERELRENL---EERIDALRARLNRAEEELERAMRAFN 797
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
74-491 |
1.17e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 52.45 E-value: 1.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 74 EKKLALELSALIEEKCKLLDKVSIVQKEYEGL---ESSLKEASFEKESTEAQSLEATYENLEQSKSKLEDEILLLEEKLE 150
Cdd:PTZ00121 1340 EAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKkkeEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKK 1419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 151 EERAKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKTTFRIFEINEERLKGaikDALNENSQLQESQKQLLQETEMMK 230
Cdd:PTZ00121 1420 ADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKA---DEAKKKAEEAKKADEAKKKAEEAK 1496
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 231 EQVNDLDKQkvalEESRAQAEQALSEKEsqietlvtsllkmKDWAAVLGEADDGNLDLDMKSGLENTAALDNQPKGALKK 310
Cdd:PTZ00121 1497 KKADEAKKA----AEAKKKADEAKKAEE-------------AKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKK 1559
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 311 LIYAAKLNASLKAlEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASLQSEKTEFESESQKLQQKLKvitelYQENEMK 390
Cdd:PTZ00121 1560 AEEKKKAEEAKKA-EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELK-----KAEEEKK 1633
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 391 LHRKLTVEENYRLEKEEKLSKVDEKISHATEEL----ETCRQRAKDL--EEELERTIHSYQGQVISHEKKAHDNWLAART 464
Cdd:PTZ00121 1634 KVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEakkaEEDKKKAEEAkkAEEDEKKAAEALKKEAEEAKKAEELKKKEAE 1713
|
410 420
....*....|....*....|....*..
gi 1720372421 465 LERNLNDLRKENAHNRQKLTETEFKFE 491
Cdd:PTZ00121 1714 EKKKAEELKKAEEENKIKAEEAKKEAE 1740
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
72-453 |
2.60e-06 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 51.11 E-value: 2.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 72 GREKKLALELSALIEEKCKLLDKVSIVQKEYE----GLESSLKEASFEKESTEA--QSLEATYENLEQSKSKLEDEILLL 145
Cdd:COG5185 180 EIFGLTLGLLKGISELKKAEPSGTVNSIKESEtgnlGSESTLLEKAKEIINIEEalKGFQDPESELEDLAQTSDKLEKLV 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 146 EEKLEEERAKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKTTFRIFEINEE--------RLKGAIKDALNE-NSQLQ 216
Cdd:COG5185 260 EQNTDLRLEKLGENAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESleeqlaaaEAEQELEESKREtETGIQ 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 217 ESQKQLLQETEMMKEQVNDLDKQK--VALEESRAQAEQALSEKESQIETLVTSLL-KMKDWAAVLGEADDgNLDLDMKSG 293
Cdd:COG5185 340 NLTAEIEQGQESLTENLEAIKEEIenIVGEVELSKSSEELDSFKDTIESTKESLDeIPQNQRGYAQEILA-TLEDTLKAA 418
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 294 LENTAALDNQPKGALKKLIYAAKLnasLKALEGERNQVYTQLSevDQVKEDLTEHIKSLESkqaSLQSEKTEFESESQKL 373
Cdd:COG5185 419 DRQIEELQRQIEQATSSNEEVSKL---LNELISELNKVMREAD--EESQSRLEEAYDEINR---SVRSKKEDLNEELTQI 490
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 374 QQKLKVITELYQENEMKLHRKL--TVEENYRLEKEEKLSKVDEKISHATEElETCRQRAKDLEEELERTIhSYQGQVISH 451
Cdd:COG5185 491 ESRVSTLKATLEKLRAKLERQLegVRSKLDQVAESLKDFMRARGYAHILAL-ENLIPASELIQASNAKTD-GQAANLRTA 568
|
..
gi 1720372421 452 EK 453
Cdd:COG5185 569 VI 570
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
66-475 |
3.33e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 50.71 E-value: 3.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 66 RSRFYVGREKKLALELSALIEEKCKLLDKVSIVQKEYEGLESSLK--EASFEKESTEAQSLEATYENLEQSKSKLEDEIL 143
Cdd:COG1196 310 RRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEeaEAELAEAEEALLEAEAELAEAEEELEELAEELL 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 144 LLEEKLEEERAKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKTTFRIFEINEERLKGAIKDALNENSQLQESQKQLL 223
Cdd:COG1196 390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 224 QETEMMKEQVNDLDkQKVALEESRAQAEQALSEKESQIETLVTSLLKMKDW---------------------AAVLGEAD 282
Cdd:COG1196 470 EEAALLEAALAELL-EELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLrglagavavligveaayeaalEAALAAAL 548
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 283 DGNLDLDMKSGLENTAALDNQPKGALKKL--------------------IYAAKLNASLKALEGERNQVYTQLSEVDQ-- 340
Cdd:COG1196 549 QNIVVEDDEVAAAAIEYLKAAKAGRATFLpldkiraraalaaalargaiGAAVDLVASDLREADARYYVLGDTLLGRTlv 628
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 341 -----------VKEDLTEHIKSLESKQASLQSEKTEFESESQKLQQKLKVITELYQENEMKLHRKLTVEENYRL-EKEEK 408
Cdd:COG1196 629 aarleaalrraVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEeEEERE 708
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720372421 409 LSKVDEKISHATEELETCRQRAKDLEEELERTIHSYQGQVISHEKKAHDNWLAARTLERNLNDLRKE 475
Cdd:COG1196 709 LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
322-439 |
5.01e-06 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 50.24 E-value: 5.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 322 KALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASLQSEKTEFEsesQKLQQKLKVITELyqENEMKLHRKltvEENY 401
Cdd:COG2433 388 KELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELE---AELEEKDERIERL--ERELSEARS---EERR 459
|
90 100 110
....*....|....*....|....*....|....*...
gi 1720372421 402 RLEKEEKLSKVDEKISHATEELETCRQRAKDLEEELER 439
Cdd:COG2433 460 EIRKDREISRLDREIERLERELEEERERIEELKRKLER 497
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
73-501 |
9.65e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 49.16 E-value: 9.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 73 REKKLALELSALIEEKCKLLDKVSIVQKEYEGLESSLKEASFEKESTEAQ--SLEATYENLEQSKSKLEDEILLLEEKLE 150
Cdd:COG1196 310 RRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAElaEAEEALLEAEAELAEAEEELEELAEELL 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 151 EERAKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKTTFRIFEINEERLKGAIKDALNENSQLQESQKQLLQETEmmk 230
Cdd:COG1196 390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLA--- 466
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 231 eqvndldkQKVALEESRAQAEQALSEKESQIETLVTSLLKMK--------DWAAVLGEAD----DGNLDLDMKSGLENTA 298
Cdd:COG1196 467 --------ELLEEAALLEAALAELLEELAEAAARLLLLLEAEadyegfleGVKAALLLAGlrglAGAVAVLIGVEAAYEA 538
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 299 ALDNQPKGALKKLIY-----AAKLNASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASLQSEKTEFESESQKL 373
Cdd:COG1196 539 ALEAALAAALQNIVVeddevAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVL 618
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 374 QQKLKVITELYQENEMKLHRKLTVEENYRLEKEEK--LSKVDEKISHATEELETCRQRAKDLEEELERTIHSYQGQVISH 451
Cdd:COG1196 619 GDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGegGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEA 698
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 1720372421 452 EKKAHDNWLAARTLERNLNDLRKENAHNRQKLTETEFKFELLEKDPYALD 501
Cdd:COG1196 699 LLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELL 748
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
196-496 |
1.36e-05 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 48.47 E-value: 1.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 196 INEERLKGaikdaLNENSQLQESQKQLLQEtemmkeqvnDLDKQKVALEESRAQAEQALSEKESQIETLVTsllKMKDWA 275
Cdd:PHA02562 171 LNKDKIRE-----LNQQIQTLDMKIDHIQQ---------QIKTYNKNIEEQRKKNGENIARKQNKYDELVE---EAKTIK 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 276 AVLGEADDGNLDLDMKSGlentaaldnQPKGALKKL-IYAAKLNASLKALEGERNqVYTQLSEVDQVKEDLTEHIKSLES 354
Cdd:PHA02562 234 AEIEELTDELLNLVMDIE---------DPSAALNKLnTAAAKIKSKIEQFQKVIK-MYEKGGVCPTCTQQISEGPDRITK 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 355 KQASLQSEKTEFESESQKlQQKLKVITELYQENEMKLHrkltveenyrlEKEEKLSKVDEKIShateeleTCRQRAKDLE 434
Cdd:PHA02562 304 IKDKLKELQHSLEKLDTA-IDELEEIMDEFNEQSKKLL-----------ELKNKISTNKQSLI-------TLVDKAKKVK 364
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720372421 435 EELERTihsyQGQVISHEKkahdnwlAARTLERNLNDLRKENAHNRQKLTETEFKFELLeKD 496
Cdd:PHA02562 365 AAIEEL----QAEFVDNAE-------ELAKLQDELDKIVKTKSELVKEKYHRGIVTDLL-KD 414
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
163-386 |
2.82e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 47.70 E-value: 2.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 163 MADISKRIQSLEDESKSLKSQVAEAKTTFRIFEINeerlkgaikdalNENSQLQESQKQLLQETEMMKEQVNDLDKQKVA 242
Cdd:COG3206 170 REEARKALEFLEEQLPELRKELEEAEAALEEFRQK------------NGLVDLSEEAKLLLQQLSELESQLAEARAELAE 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 243 LEESRAQAEQALSEKESQIETLVTSllkmkdwaAVLGEADDGNLDLDMKSGLENTAALDNQPKgalkkliyaaklnasLK 322
Cdd:COG3206 238 AEARLAALRAQLGSGPDALPELLQS--------PVIQQLRAQLAELEAELAELSARYTPNHPD---------------VI 294
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720372421 323 ALEGERNQVYTQL-SEVDQVKEDLTEHIKSLESKQASLQSEKTEFESESQKLQQKLKVITELYQE 386
Cdd:COG3206 295 ALRAQIAALRAQLqQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLERE 359
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
168-485 |
2.86e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 47.66 E-value: 2.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 168 KRIQSLEDESKSLKSQVAEAKTTFRIFEINEERLKGAIKDALNENS---------------------------------- 213
Cdd:pfam02463 153 ERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQelklkeqakkaleyyqlkekleleeeyllyldyl 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 214 QLQESQKQLLQETEMMKEQVNDLDKQKVALEESRAQAEQALSEKESQIETLVTSLLKMKDWAAVLGEADDGNLDLDMKSG 293
Cdd:pfam02463 233 KLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDD 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 294 LENTAALDNQPKGALKKLIYAAKLNASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASLQSEKTEFESESQKL 373
Cdd:pfam02463 313 EEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKL 392
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 374 QQKLKVITELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETCRQRAKDLEEELERTIHSYQGQVISHEK 453
Cdd:pfam02463 393 KEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSED 472
|
330 340 350
....*....|....*....|....*....|..
gi 1720372421 454 KAHDNWLAARTLERNLNDLRKENAHNRQKLTE 485
Cdd:pfam02463 473 LLKETQLVKLQEQLELLLSRQKLEERSQKESK 504
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
157-528 |
2.94e-05 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 47.77 E-value: 2.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 157 SEQDELMADISKRIQSLEDESKslksqvaeAKTTFRIFEINEERLKGA-IKDALNENSQLQESQKQLLQETEMMKEQVND 235
Cdd:COG5022 806 LGSRKEYRSYLACIIKLQKTIK--------REKKLRETEEVEFSLKAEvLIQKFGRSLKAKKRFSLLKKETIYLQSAQRV 877
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 236 LDKQKVALE-----ESRAQAEQALSEKESQIETLV----TSLLK--------MKDWAAVLGEADDGNlDLDMKSGLENTA 298
Cdd:COG5022 878 ELAERQLQElkidvKSISSLKLVNLELESEIIELKkslsSDLIEnlefktelIARLKKLLNNIDLEE-GPSIEYVKLPEL 956
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 299 ALDNQPKGALKKLiyAAKLNASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASLqSEKTEFESESQKLQQKLK 378
Cdd:COG5022 957 NKLHEVESKLKET--SEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQEST-KQLKELPVEVAELQSASK 1033
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 379 VI----TELYQENEM-KLHRKLTVEENYrLEKEEKLSKVDEKISHATEELETCRQRAKDLEEELERTIHSYQGQVISHEK 453
Cdd:COG5022 1034 IIssesTELSILKPLqKLKGLLLLENNQ-LQARYKALKLRRENSLLDDKQLYQLESTENLLKTINVKDLEVTNRNLVKPA 1112
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720372421 454 KAHDNWLAARTlerNLNDLRKENAHNRQKLTETEFKFELLEKDPYALDVPNTAFGREHSPYGPSPLGRPPSETRA 528
Cdd:COG5022 1113 NVLQFIVAQMI---KLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRLYQ 1184
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
168-475 |
3.04e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 47.81 E-value: 3.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 168 KRIQSLEDESKSLKSQVAEAKTTFrifeinEERLKGAIKDALNENSQLQESQKqllqETEMMKEQVNDLDKQKVALEESR 247
Cdd:pfam15921 317 RQLSDLESTVSQLRSELREAKRMY------EDKIEELEKQLVLANSELTEART----ERDQFSQESGNLDDQLQKLLADL 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 248 AQAEQALSEKESQIETLvtsllkmkdWAAVLG----------EADDGNLDLDMKSGLenTAALDNQPKGALKKLIYAAK- 316
Cdd:pfam15921 387 HKREKELSLEKEQNKRL---------WDRDTGnsitidhlrrELDDRNMEVQRLEAL--LKAMKSECQGQMERQMAAIQg 455
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 317 LNASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASLQSEKTEFESESQKLQQKLKVITELYQENEMKLhrklt 396
Cdd:pfam15921 456 KNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKL----- 530
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 397 vEENYRLEKEEklskvdEKISHATEELETCRQRAKDLE---EELERTIHSYQGQVISHEKKAHDNWLAARTLERNLNDLR 473
Cdd:pfam15921 531 -QELQHLKNEG------DHLRNVQTECEALKLQMAEKDkviEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRR 603
|
..
gi 1720372421 474 KE 475
Cdd:pfam15921 604 LE 605
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
166-270 |
3.13e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 47.47 E-value: 3.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 166 ISKRIQSLEDESKSLKSQV---AEAKTTFRIFEINEE--RLKGAIKDALNE-NSQLQESQKQLLQETEMMKEQVNDLDKQ 239
Cdd:PRK12704 29 AEAKIKEAEEEAKRILEEAkkeAEAIKKEALLEAKEEihKLRNEFEKELRErRNELQKLEKRLLQKEENLDRKLELLEKR 108
|
90 100 110
....*....|....*....|....*....|....
gi 1720372421 240 KVALEESR---AQAEQALSEKESQIETLVTSLLK 270
Cdd:PRK12704 109 EEELEKKEkelEQKQQELEKKEEELEELIEEQLQ 142
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
153-495 |
3.80e-05 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 47.48 E-value: 3.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 153 RAKHSEQDELMADISKRiqSLEDESKSLKSQVAEAKTtfRIFEI------NEERLKGAIKDALNENSQLQESQKQLLQET 226
Cdd:pfam01576 195 RLKKEEKGRQELEKAKR--KLEGESTDLQEQIAELQA--QIAELraqlakKEEELQAALARLEEETAQKNNALKKIRELE 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 227 EMMKEQVNDLDKQKVAleesRAQAEQALSEKESQIETLVTSLLKMKDWAAV---LGEADDGNLDLDMKSGLENTAALDNQ 303
Cdd:pfam01576 271 AQISELQEDLESERAA----RNKAEKQRRDLGEELEALKTELEDTLDTTAAqqeLRSKREQEVTELKKALEEETRSHEAQ 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 304 PKGALKKLIYA---------------AKLNASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASLQS------- 361
Cdd:pfam01576 347 LQEMRQKHTQAleelteqleqakrnkANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQArlseser 426
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 362 EKTEFESESQKLQQKLKVITELYQENEMKLHrkltveenyRLEKEekLSKVDEKIsHATEEL--ETCRQ------RAKDL 433
Cdd:pfam01576 427 QRAELAEKLSKLQSELESVSSLLNEAEGKNI---------KLSKD--VSSLESQL-QDTQELlqEETRQklnlstRLRQL 494
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720372421 434 EEE-----------------LERTIHSYQGQVISHEKKAHDNWLAARTLERNLNDLRKENAHNRQKLTETEFKFELLEK 495
Cdd:pfam01576 495 EDErnslqeqleeeeeakrnVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEK 573
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
91-439 |
4.33e-05 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 47.34 E-value: 4.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 91 LLDKVSIVQKEYEGLESSLKEA--SFEKESTEAQSLEATYENLEQSKSKLEDEILLLEEKLEEERAKHSEQDELMADISK 168
Cdd:PRK02224 312 VEARREELEDRDEELRDRLEECrvAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEE 391
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 169 RIQSLEDESKSLKSQVAEAKTTFRIFEINEERLKGAIK----------DALNENSQLQESQK-----QLLQETEMMkEQV 233
Cdd:PRK02224 392 EIEELRERFGDAPVDLGNAEDFLEELREERDELREREAeleatlrtarERVEEAEALLEAGKcpecgQPVEGSPHV-ETI 470
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 234 NDLDKQKVALEESRAQAEQALSEKESQIETLvTSLLKMKDWAAVLGEADDGNLDL--DMKSGLENTA-ALDNQPKGALKK 310
Cdd:PRK02224 471 EEDRERVEELEAELEDLEEEVEEVEERLERA-EDLVEAEDRIERLEERREDLEELiaERRETIEEKReRAEELRERAAEL 549
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 311 LIYAAKLNASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLEsKQASLQSEKTEFESESQKLQQKLKVITELYQENEMK 390
Cdd:PRK02224 550 EAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEIERLREKREALAELNDERRER 628
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 391 L----HRKLTVEENY---RLEK--------EEKLSKVDEKISHATE-----------------ELETCRQRAKDLEEELE 438
Cdd:PRK02224 629 LaekrERKRELEAEFdeaRIEEaredkeraEEYLEQVEEKLDELREerddlqaeigaveneleELEELRERREALENRVE 708
|
.
gi 1720372421 439 R 439
Cdd:PRK02224 709 A 709
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
168-496 |
7.11e-05 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 46.55 E-value: 7.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 168 KRIQSLEDESKSLKSQVAEAKTTFRIFEINEERLKGAIKDALNENSQLQESQKQLLQETEMMKEQVNDLDKQKVALEESr 247
Cdd:TIGR04523 54 KELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQ- 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 248 aqaeqaLSEKESQIETLVTSLLKMKDWAAVLGEADDgnlDLD-MKSGLENTaaldnqpKGALKKLIyaAKLNASLKALEG 326
Cdd:TIGR04523 133 ------KKENKKNIDKFLTEIKKKEKELEKLNNKYN---DLKkQKEELENE-------LNLLEKEK--LNIQKNIDKIKN 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 327 ERNQVYTQLSEVDQVKED---LTEHIKSLESKQASL-------QSEKTEFESESQKLQQKLKVITELYQENEMKLHRK-L 395
Cdd:TIGR04523 195 KLLKLELLLSNLKKKIQKnksLESQISELKKQNNQLkdniekkQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKqK 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 396 TVEENYRL--EKEEKLSKVDEKIShateELEtcRQRAKDLEEELERTIHSYQGQVISHEKKAHDNWLAARTLERNLNDLR 473
Cdd:TIGR04523 275 ELEQNNKKikELEKQLNQLKSEIS----DLN--NQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLK 348
|
330 340 350
....*....|....*....|....*....|
gi 1720372421 474 KE-------NAHNRQKLTETEFKFELLEKD 496
Cdd:TIGR04523 349 KEltnseseNSEKQRELEEKQNEIEKLKKE 378
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
76-435 |
8.42e-05 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 46.19 E-value: 8.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 76 KLALELSALIEEKCKLLDKVSIVQKEYEGLESSLKE--ASFEKESTEAQSLEATYENLEQSKSKLEDEILLLEEKLEEER 153
Cdd:PRK02224 262 DLRETIAETEREREELAEEVRDLRERLEELEEERDDllAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHN 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 154 AKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKTTFR-----IFEINEE--RLKGAIKDALNENSQLQESQKQLLQET 226
Cdd:PRK02224 342 EEAESLREDADDLEERAEELREEAAELESELEEAREAVEdrreeIEELEEEieELRERFGDAPVDLGNAEDFLEELREER 421
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 227 EMMKEQVNDLDKQKVALEESRAQAEQ---------------------ALSEKESQIETLVTSLLKMKDWAAvlgeaddgn 285
Cdd:PRK02224 422 DELREREAELEATLRTARERVEEAEAlleagkcpecgqpvegsphveTIEEDRERVEELEAELEDLEEEVE--------- 492
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 286 ldldmksglentaaldnqpkgALKKLIYAAKlnaSLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASLQSEKTE 365
Cdd:PRK02224 493 ---------------------EVEERLERAE---DLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAE 548
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720372421 366 FESESQklqQKLKVITELYQENEMKLHRKLTVEE-----NYRLEKEEKLSKVDEKISHATEELETCRQRAKDLEE 435
Cdd:PRK02224 549 LEAEAE---EKREAAAEAEEEAEEAREEVAELNSklaelKERIESLERIRTLLAAIADAEDEIERLREKREALAE 620
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
76-495 |
1.06e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 46.19 E-value: 1.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 76 KLALELSALIEEKCKLLDKVSIVQKEYEGLESSLKEASFEKEstEAQSLEATYENL-----EQSKSKLEDEILLLEEKLE 150
Cdd:TIGR00606 420 KERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIK--ELQQLEGSSDRIleldqELRKAERELSKAEKNSLTE 497
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 151 EERAKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKTTF-----------RIFEIN---EERLKGAIKDALNEnSQLQ 216
Cdd:TIGR00606 498 TLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEmltkdkmdkdeQIRKIKsrhSDELTSLLGYFPNK-KQLE 576
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 217 ESQKQLLQETEMMKEQVNDLDKQKVALEESRAQAEQALSEKESQIETLVTSLLKMKDWAAVlgEADDGNLDLDMKSGLEN 296
Cdd:TIGR00606 577 DWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDE--ESDLERLKEEIEKSSKQ 654
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 297 TAALdnqpkgALKKLIYAAKLNASLkalegERNQVYTQLSEVD-QVKEDLTEHIKSLESKQASLQSEKTEFESESQKLQQ 375
Cdd:TIGR00606 655 RAML------AGATAVYSQFITQLT-----DENQSCCPVCQRVfQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEK 723
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 376 KLKVITELY--QENEMKLHRKLTVEENYRLEK-EEKLSKVDEKISHATEELETC---RQRAKDLEEELErTIHSYQGQVI 449
Cdd:TIGR00606 724 RRDEMLGLApgRQSIIDLKEKEIPELRNKLQKvNRDIQRLKNDIEEQETLLGTImpeEESAKVCLTDVT-IMERFQMELK 802
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 1720372421 450 SHEKKAHD--NWLAARTLERNLNDLRKENAHNRQKLTETEFKFELLEK 495
Cdd:TIGR00606 803 DVERKIAQqaAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRK 850
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
75-264 |
1.08e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.21 E-value: 1.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 75 KKLALELSALIEEKCKLLDKVSIVQKEYEGLESSLKEASFEKESTEAQsLEATYENLEQSKskledeillleekleeera 154
Cdd:COG3883 19 QAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAE-IDKLQAEIAEAE------------------- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 155 khSEQDELMADISKRIQSL--EDESKSLKSQVAEAK--TTF--RIFEINeeRLKGAIKDALNEnsqLQESQKQLLQETEM 228
Cdd:COG3883 79 --AEIEERREELGERARALyrSGGSVSYLDVLLGSEsfSDFldRLSALS--KIADADADLLEE---LKADKAELEAKKAE 151
|
170 180 190
....*....|....*....|....*....|....*.
gi 1720372421 229 MKEQVNDLDKQKVALEESRAQAEQALSEKESQIETL 264
Cdd:COG3883 152 LEAKLAELEALKAELEAAKAELEAQQAEQEALLAQL 187
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
80-497 |
1.25e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 45.60 E-value: 1.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 80 ELSALIEEKCKLLDKVSIVQKEYEGLESSLKEASFEKESTEAQSLEATYENLEQSKSkleDEILLLEEKLEEERAKHSEQ 159
Cdd:pfam12128 355 ELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLA---VAEDDLQALESELREQLEAG 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 160 DELMADISKRIQSLEDESKSLKSQVAEAKTTFRIFEINEERLKGAIKDALNENSQLQESQKQLLQETEMMKEQVNDLDKQ 239
Cdd:pfam12128 432 KLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQA 511
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 240 KVALEESRAQAEQALSEKESQIETLVTSLLK-MKDWAAVLGEADDGNL----DLDmksglenTAALDNQPKGALKklIYA 314
Cdd:pfam12128 512 SRRLEERQSALDELELQLFPQAGTLLHFLRKeAPDWEQSIGKVISPELlhrtDLD-------PEVWDGSVGGELN--LYG 582
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 315 AKLNasLKALEGERNQVYTQL--SEVDQVKEDLtehiKSLESKQASLQSEKTEFESESQKLQQKLKVITELYQENEMKLH 392
Cdd:pfam12128 583 VKLD--LKRIDVPEWAASEEElrERLDKAEEAL----QSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLR 656
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 393 RKLTVEENYRLEKEEKLSkvdEKISHATEELETCRQRAKDLEEELERTIHSYQGQVISHEKKAHDNWLAARTLERNLNDL 472
Cdd:pfam12128 657 RLFDEKQSEKDKKNKALA---ERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLAL 733
|
410 420 430
....*....|....*....|....*....|..
gi 1720372421 473 -------RKENAHNRQKLTETEFKFELLEKDP 497
Cdd:pfam12128 734 lkaaiaaRRSGAKAELKALETWYKRDLASLGV 765
|
|
| RNase_Y_N |
pfam12072 |
RNase Y N-terminal region; |
168-265 |
1.27e-04 |
|
RNase Y N-terminal region;
Pssm-ID: 463456 [Multi-domain] Cd Length: 201 Bit Score: 43.72 E-value: 1.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 168 KRIQSLEDESKSLKS---QVAEAKTTFRIFEINEE--RLKGAIKDALNE-NSQLQESQKQLLQETEMMKEQVNDLDKQKV 241
Cdd:pfam12072 27 AKIGSAEELAKRIIEeakKEAETKKKEALLEAKEEihKLRAEAERELKErRNELQRQERRLLQKEETLDRKDESLEKKEE 106
|
90 100
....*....|....*....|....*..
gi 1720372421 242 AL---EESRAQAEQALSEKESQIETLV 265
Cdd:pfam12072 107 SLekkEKELEAQQQQLEEKEEELEELI 133
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
160-447 |
1.32e-04 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 45.66 E-value: 1.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 160 DELMADIS------KRIQSLEDESKSLKSQVAEAKTTFRIFEINEERLKGAIKDALNENSQLQESQKQLLQETEMMKEQV 233
Cdd:PRK01156 176 DMLRAEISnidyleEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYE 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 234 NDLDKQkvaleESRAQAEQALSEKESQIETLVTSLLKMKDWAA---VLGEADDGNLDLDMKSGLENTAALDNQPKGALKK 310
Cdd:PRK01156 256 SEIKTA-----ESDLSMELEKNNYYKELEERHMKIINDPVYKNrnyINDYFKYKNDIENKKQILSNIDAEINKYHAIIKK 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 311 LiyaaklnaslKALEGERNQVYTQLSEvdqvKEDLTEHIKSLESKQASLQSEKTEFESESQKLQQKLKVITELYQENEMK 390
Cdd:PRK01156 331 L----------SVLQKDYNDYIKKKSR----YDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEI 396
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 391 LHRKLTVEENYRLEKEEKLSKVDE---KISHATEELETCRQRakdlEEELERTIHSYQGQ 447
Cdd:PRK01156 397 LKIQEIDPDAIKKELNEINVKLQDissKVSSLNQRIRALREN----LDELSRNMEMLNGQ 452
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
74-439 |
1.77e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 45.31 E-value: 1.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 74 EKKLALELSALIEEKCKLLDKVSIVQKEYEGLESSLKEAsfEKESTEAQSLEATYENLEQSKSKLEDEILLLEEKLEEER 153
Cdd:COG1196 357 EAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA--AELAAQLEELEEAEEALLERLERLEEELEELEEALAELE 434
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 154 AKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKTTFRIFEINEERLKGAIKDALNENSQLQESQKQLLQETEMMKEQV 233
Cdd:COG1196 435 EEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAAL 514
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 234 NDLDKQKV----------------ALEESRAQAEQALSEKESQIETLVTSLLKMK------------------------- 272
Cdd:COG1196 515 LLAGLRGLagavavligveaayeaALEAALAAALQNIVVEDDEVAAAAIEYLKAAkagratflpldkiraraalaaalar 594
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 273 ---DWAAVLGEADDGNLDLDMKSGLENTAALDNQPKGALKKLIYAAKLNASLKALEGERNQVY-----------TQLSEV 338
Cdd:COG1196 595 gaiGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSaggsltggsrrELLAAL 674
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 339 DQVKEDLTEHIKSLESKQASLQSEKTEFESESQKLQQKLKVITELYQENEMKLHRKLTVEENYR---LEKEEKLSKVDEK 415
Cdd:COG1196 675 LEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLeelLEEEELLEEEALE 754
|
410 420
....*....|....*....|....
gi 1720372421 416 ISHATEELETCRQRAKDLEEELER 439
Cdd:COG1196 755 ELPEPPDLEELERELERLEREIEA 778
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
321-501 |
2.32e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.76 E-value: 2.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 321 LKALEGERNQVYTQLSEVDQvkedLTEHIKSLESKQASLQSEKTEFESESQKLQQKLKVItELYQENEmKLHRKLTvEEN 400
Cdd:COG4717 73 LKELEEELKEAEEKEEEYAE----LQEELEELEEELEELEAELEELREELEKLEKLLQLL-PLYQELE-ALEAELA-ELP 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 401 YRLEK-EEKLskvdEKISHATEELETCRQRAKDLEEELERTIHSYQgqvISHEKKAHDNWLAARTLERNLNDLRKENAHN 479
Cdd:COG4717 146 ERLEElEERL----EELRELEEELEELEAELAELQEELEELLEQLS---LATEEELQDLAEELEELQQRLAELEEELEEA 218
|
170 180
....*....|....*....|..
gi 1720372421 480 RQKLTETEFKFELLEKDPYALD 501
Cdd:COG4717 219 QEELEELEEELEQLENELEAAA 240
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
73-451 |
2.46e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.76 E-value: 2.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 73 REKKLALELSALIEEKCKLLDKVSIVQKEYEGLESSLKEasFEKESTEAQSLEATYENLEQS-KSKLEDEILLLEEKLEE 151
Cdd:COG4717 119 EKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEE--LRELEEELEELEAELAELQEElEELLEQLSLATEEELQD 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 152 ERAKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKTTFRIFEINEERLKG--------------AIKDALNENSQ--- 214
Cdd:COG4717 197 LAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEArlllliaaallallGLGGSLLSLILtia 276
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 215 -------------LQESQKQLLQETEMMKEQVNDLDKQKVALEESRAQAEQALSEKESQIETLVTSLLKMKDWAAVLGEA 281
Cdd:COG4717 277 gvlflvlgllallFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREA 356
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 282 DDGNLDLDMKSGLENTAALDNQPK-GALKKLIYAAKLNASLKALEGERNQVYTQLSE---------VDQVKEDLTEHIKS 351
Cdd:COG4717 357 EELEEELQLEELEQEIAALLAEAGvEDEEELRAALEQAEEYQELKEELEELEEQLEEllgeleellEALDEEELEEELEE 436
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 352 LESKQASLQSEKTEFESESQKLQQKLKvitelyqenemklhrkltveenyRLEKEEKLSKVDEKISHATEELETCRQR-- 429
Cdd:COG4717 437 LEEELEELEEELEELREELAELEAELE-----------------------QLEEDGELAELLQELEELKAELRELAEEwa 493
|
410 420
....*....|....*....|....*..
gi 1720372421 430 -----AKDLEEELERTIHSYQGQVISH 451
Cdd:COG4717 494 alklaLELLEEAREEYREERLPPVLER 520
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
105-273 |
3.12e-04 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 43.65 E-value: 3.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 105 LESSLKEASFEKESTEAQsLEATYENLEQSKSKLEDEILLLEEKLEEERAKHSEQDELMADIsKRIQSLEDESKSLKSQV 184
Cdd:pfam15905 168 LEAKMKEVMAKQEGMEGK-LQVTQKNLEHSKGKVAQLEEKLVSTEKEKIEEKSETEKLLEYI-TELSCVSEQVEKYKLDI 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 185 AEAKttfrifEINEERlkgaikdalneNSQLQESQKQLLQETEMMKEQVNDLDKQKVALEESRaqaEQALSEKESQIETL 264
Cdd:pfam15905 246 AQLE------ELLKEK-----------NDEIESLKQSLEEKEQELSKQIKDLNEKCKLLESEK---EELLREYEEKEQTL 305
|
....*....
gi 1720372421 265 VTSLLKMKD 273
Cdd:pfam15905 306 NAELEELKE 314
|
|
| PRK14473 |
PRK14473 |
F0F1 ATP synthase subunit B; Provisional |
167-266 |
3.29e-04 |
|
F0F1 ATP synthase subunit B; Provisional
Pssm-ID: 172948 [Multi-domain] Cd Length: 164 Bit Score: 42.22 E-value: 3.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 167 SKRIQSLEDESKSLKSQVAEAKTTFrifeinEERLKGAIKDALNENSQLQESQKQllQETEMMKEQVNDLDKQKvalEES 246
Cdd:PRK14473 41 TRRIEESLRDAEKVREQLANAKRDY------EAELAKARQEAAKIVAQAQERARA--QEAEIIAQARREAEKIK---EEA 109
|
90 100
....*....|....*....|....
gi 1720372421 247 RAQAEQ----ALSEKESQIETLVT 266
Cdd:PRK14473 110 RAQAEQerqrMLSELKSQIADLVT 133
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
160-444 |
3.97e-04 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 44.27 E-value: 3.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 160 DELMADISKRiQSLEDESKSLKSQVAEAKTTFRIFE---------INEERLKGAIKDALNENSQL----QESQKQLLQET 226
Cdd:TIGR01612 1486 NELKEHIDKS-KGCKDEADKNAKAIEKNKELFEQYKkdvtellnkYSALAIKNKFAKTKKDSEIIikeiKDAHKKFILEA 1564
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 227 EMMKEQVNDLDKQKVALEESRA---QAEQALSEKESQIETLVTSLLKMKDwaavlgeaddgnldldmksglentaaldnq 303
Cdd:TIGR01612 1565 EKSEQKIKEIKKEKFRIEDDAAkndKSNKAAIDIQLSLENFENKFLKISD------------------------------ 1614
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 304 pkgaLKKliyaaKLNASLKALEGERNQVY--------TQLSEVDQVKEDLTEHIKSLESKQASLQSEKTEFEsesqKLQQ 375
Cdd:TIGR01612 1615 ----IKK-----KINDCLKETESIEKKISsfsidsqdTELKENGDNLNSLQEFLESLKDQKKNIEDKKKELD----ELDS 1681
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720372421 376 KLKVItelyqENEMKLHRKltveeNYRLEKEEklsKVDEKISHATEELETCRQRakdLEEELERTIHSY 444
Cdd:TIGR01612 1682 EIEKI-----EIDVDQHKK-----NYEIGIIE---KIKEIAIANKEEIESIKEL---IEPTIENLISSF 1734
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
315-462 |
3.98e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 42.60 E-value: 3.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 315 AKLNASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASLQSEKTEFES---------ESQKLQQKLKvitelYQ 385
Cdd:COG1579 27 KELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEqlgnvrnnkEYEALQKEIE-----SL 101
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720372421 386 ENEMKLHRKLTVEENYRLE-KEEKLSKVDEKISHATEELETCRQRAKDLEEELERTIHSYQGQVISHEKKAHDNWLAA 462
Cdd:COG1579 102 KRRISDLEDEILELMERIEeLEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPELLAL 179
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
153-489 |
4.60e-04 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 43.66 E-value: 4.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 153 RAKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKTTFrifEINEERLKGAIKDALNENSQLQESQKQLLQETEMMKEQ 232
Cdd:pfam10174 351 RLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDML---DVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSL 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 233 VNDLDKQKVALeesrAQAEQALSEKESQIETLVTSllKMKDWAAVLGEADDGNLDL-DMKSGL--------ENTAALDNQ 303
Cdd:pfam10174 428 QTDSSNTDTAL----TTLEEALSEKERIIERLKEQ--REREDRERLEELESLKKENkDLKEKVsalqpeltEKESSLIDL 501
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 304 PKGALKKLIYAAKLNASLKALEGE-----------RNQVYT--QLSEVDQVKEDLTEHIKSLESKQASLQSEKTEFESES 370
Cdd:pfam10174 502 KEHASSLASSGLKKDSKLKSLEIAveqkkeecsklENQLKKahNAEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEV 581
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 371 QKLQQKLKvitelyqenEMklhrkltveENYRLEKEEKLSKVDEKISHATEELETCRQRAKDLEEELERTihsyQGQVIS 450
Cdd:pfam10174 582 ERLLGILR---------EV---------ENEKNDKDKKIAELESLTLRQMKEQNKKVANIKHGQQEMKKK----GAQLLE 639
|
330 340 350
....*....|....*....|....*....|....*....
gi 1720372421 451 HEKKAHDNwLAARTLERNLNDLRKENAHNRQKLTETEFK 489
Cdd:pfam10174 640 EARRREDN-LADNSQQLQLEELMGALEKTRQELDATKAR 677
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
164-457 |
5.17e-04 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 43.56 E-value: 5.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 164 ADISKRIQSLEDESKSLKSQvaeaKTTFRIFEINEERLKGAIKDALNENSQLQESQK------QLLQET----------- 226
Cdd:pfam05483 99 AELKQKENKLQENRKIIEAQ----RKAIQELQFENEKVSLKLEEEIQENKDLIKENNatrhlcNLLKETcarsaektkky 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 227 EMMKEQV--------NDLDKQKVALEESRAQAEQA-------------------------LSEKESQIETLVTSLL---- 269
Cdd:pfam05483 175 EYEREETrqvymdlnNNIEKMILAFEELRVQAENArlemhfklkedhekiqhleeeykkeINDKEKQVSLLLIQITeken 254
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 270 KMKDWAAVLGEADDGNLDLDMKSGL--ENTAALdNQPKGALKKLIYAAKLN-----ASLKALEgERNQVYTQlsEVDQVK 342
Cdd:pfam05483 255 KMKDLTFLLEESRDKANQLEEKTKLqdENLKEL-IEKKDHLTKELEDIKMSlqrsmSTQKALE-EDLQIATK--TICQLT 330
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 343 EDLTEHIKSLESKQASLQSEKTEFESESQKLQQKLKVITELYQENEMKLhRKLTVEENYRLEKEEKLSKVDEKISHATEE 422
Cdd:pfam05483 331 EEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQL-KIITMELQKKSSELEEMTKFKNNKEVELEE 409
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 1720372421 423 LETC----------RQRAKDLEEELERTIHSYQGQVISHEKKAHD 457
Cdd:pfam05483 410 LKKIlaedeklldeKKQFEKIAEELKGKEQELIFLLQAREKEIHD 454
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
170-388 |
6.08e-04 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 43.36 E-value: 6.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 170 IQSLEDESKSLKSQVAEAKTTFRIFEiNEERLKGAIKDALNENSQLQesqKQLLQETEMMKEQVNDLDKQKVALEESRAQ 249
Cdd:PRK11281 41 VQAQLDALNKQKLLEAEDKLVQQDLE-QTLALLDKIDRQKEETEQLK---QQLAQAPAKLRQAQAELEALKDDNDEETRE 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 250 AEQALS--EKESQIETLVTSLlkmKDWAAVLGEAddgNLDL------------DMKSGLENTAALDNQPKG--ALKKLIY 313
Cdd:PRK11281 117 TLSTLSlrQLESRLAQTLDQL---QNAQNDLAEY---NSQLvslqtqperaqaALYANSQRLQQIRNLLKGgkVGGKALR 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 314 A---AKLNASLKALEGE----RN--QVYTQLSEVDQVKEDL-TEHIKSLESKQASLQ----------SEKTEFESESQKL 373
Cdd:PRK11281 191 PsqrVLLQAEQALLNAQndlqRKslEGNTQLQDLLQKQRDYlTARIQRLEHQLQLLQeainskrltlSEKTVQEAQSQDE 270
|
250
....*....|....*
gi 1720372421 374 QQKLKVITELYQENE 388
Cdd:PRK11281 271 AARIQANPLVAQELE 285
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
106-485 |
6.61e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 43.24 E-value: 6.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 106 ESSLKEASFEKESTEAQSLEATYENLEQSKSKLEDEILLLEEKLEEERAKHSEQDELMADISKRIQSLEDESKSLKSQVA 185
Cdd:pfam01576 6 EMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRLE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 186 EAKTTFRIFEINEERLKGAIKDaLNENSQLQESQKQLLQ---------------ETEMMKEQVNDLDKQKVALEESRAQA 250
Cdd:pfam01576 86 EEEERSQQLQNEKKKMQQHIQD-LEEQLDEEEAARQKLQlekvtteakikkleeDILLLEDQNSKLSKERKLLEERISEF 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 251 EQALSEKESQIETLvtSLLKMKDWAavlgeaddgnldldMKSGLENTAALDNQPKGALKKLiyaaklnasLKALEGERNQ 330
Cdd:pfam01576 165 TSNLAEEEEKAKSL--SKLKNKHEA--------------MISDLEERLKKEEKGRQELEKA---------KRKLEGESTD 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 331 VYTQLSEVDQVKEDLTehiKSLESKQASLQSEKTEFESESQKLQQKLKVITELyQENEMKLHRKLTVEENYRlEKEEKLS 410
Cdd:pfam01576 220 LQEQIAELQAQIAELR---AQLAKKEEELQAALARLEEETAQKNNALKKIREL-EAQISELQEDLESERAAR-NKAEKQR 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 411 KvdekisHATEELETCRqraKDLEEELERT-----IHSYQGQVISHEKKAHDNwlAARTLERNLNDLRKENAHNRQKLTE 485
Cdd:pfam01576 295 R------DLGEELEALK---TELEDTLDTTaaqqeLRSKREQEVTELKKALEE--ETRSHEAQLQEMRQKHTQALEELTE 363
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
91-402 |
7.17e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 43.50 E-value: 7.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 91 LLDKVSIVQKEYEGLESSlkEASFEKESTEAQS--LEATYENLEQSKSKLEDEILLLEEKLEEERAKHSEQDELMADISK 168
Cdd:TIGR00606 787 CLTDVTIMERFQMELKDV--ERKIAQQAAKLQGsdLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKS 864
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 169 RIQSLEDESKSL-----KSQVAEAKTTFRIFEINEerLKGAIKDALNENSQLQESQKQLLQETE---------------- 227
Cdd:TIGR00606 865 KTNELKSEKLQIgtnlqRRQQFEEQLVELSTEVQS--LIREIKDAKEQDSPLETFLEKDQQEKEelissketsnkkaqdk 942
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 228 --MMKEQVNDLDKQKVALEESRAQA-EQALSEKESQIETLVTSLLKMKDWAAVLGEaDDGNLDLDMKSglentaalDNQP 304
Cdd:TIGR00606 943 vnDIKEKVKNIHGYMKDIENKIQDGkDDYLKQKETELNTVNAQLEECEKHQEKINE-DMRLMRQDIDT--------QKIQ 1013
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 305 KGALKKLIYAAKLNASLKALEGERNQVYTQLSEvDQVKEDLTEHIKsLESKQASLQSEKTEFESESQKLQQKLKVITELY 384
Cdd:TIGR00606 1014 ERWLQDNLTLRKRENELKEVEEELKQHLKEMGQ-MQVLQMKQEHQK-LEENIDLIKRNHVLALGRQKGYEKEIKHFKKEL 1091
|
330
....*....|....*...
gi 1720372421 385 QENEMKlhrklTVEENYR 402
Cdd:TIGR00606 1092 REPQFR-----DAEEKYR 1104
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
161-356 |
7.34e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 43.37 E-value: 7.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 161 ELMADISKRIQSLEdESKSLKSQVAEAKTTFRIFEINEERL---KGAIKDALNEN--SQLQESQKQLLQETEMMKEQVND 235
Cdd:COG4913 242 EALEDAREQIELLE-PIRELAERYAAARERLAELEYLRAALrlwFAQRRLELLEAelEELRAELARLEAELERLEARLDA 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 236 LDKQKVALEESRAQA--------EQALSEKESQIETLVTSLLKMKDWAAVLGEAddgnLDLDMKSGLENTAALDNQpkga 307
Cdd:COG4913 321 LREELDELEAQIRGNggdrleqlEREIERLERELEERERRRARLEALLAALGLP----LPASAEEFAALRAEAAAL---- 392
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1720372421 308 lkkliyAAKLNASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQ 356
Cdd:COG4913 393 ------LEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRK 435
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
163-494 |
7.34e-04 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 42.90 E-value: 7.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 163 MADISKRIQSLEDESKSLKsqVAEAKTtfrifEIN--EERLKGA---IKDALNENSQLQESQKQLLQETEMMKEQVNDLD 237
Cdd:PRK04778 81 LPDIEEQLFEAEELNDKFR--FRKAKH-----EINeiESLLDLIeedIEQILEELQELLESEEKNREEVEQLKDLYRELR 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 238 KQkvaLEESRAQAEQALSEKESQIETLVTSLLKMKDwaavlgEADDGN--------LDLDMKsglenTAALDNQ----PK 305
Cdd:PRK04778 154 KS---LLANRFSFGPALDELEKQLENLEEEFSQFVE------LTESGDyveareilDQLEEE-----LAALEQImeeiPE 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 306 GaLKKLiyAAKLNASLKALEgernQVYTQLSE---------VDQVKEDLTEHIKSLESKQASLqsEKTEFESESQKLQQK 376
Cdd:PRK04778 220 L-LKEL--QTELPDQLQELK----AGYRELVEegyhldhldIEKEIQDLKEQIDENLALLEEL--DLDEAEEKNEEIQER 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 377 lkvITELYQ--ENEMKLHRKLtveenyrlekEEKLSKVDEKISHATEEletcrqrAKDLEEELERTIHSYQgqvISHEKK 454
Cdd:PRK04778 291 ---IDQLYDilEREVKARKYV----------EKNSDTLPDFLEHAKEQ-------NKELKEEIDRVKQSYT---LNESEL 347
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 1720372421 455 AHdnwlaARTLERNLNDLRKENAHNRQKLTETEFKFELLE 494
Cdd:PRK04778 348 ES-----VRQLEKQLESLEKQYDEITERIAEQEIAYSELQ 382
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
158-496 |
8.73e-04 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 42.89 E-value: 8.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 158 EQDELMADISKRIQSLEDESkslkSQVAEAKTTFrifeinEERL--KGAIKDALNEnsQLQESQKQLLQETEMMKEQVND 235
Cdd:pfam10174 412 DKDKQLAGLKERVKSLQTDS----SNTDTALTTL------EEALseKERIIERLKE--QREREDRERLEELESLKKENKD 479
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 236 LDKQKVALEESRAQAEQALSEKESQIETLVTSLLKmKDwaavlgeADDGNLDLDMKSGLENTAALDNQPKGALKKLIYA- 314
Cdd:pfam10174 480 LKEKVSALQPELTEKESSLIDLKEHASSLASSGLK-KD-------SKLKSLEIAVEQKKEECSKLENQLKKAHNAEEAVr 551
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 315 --AKLNASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASLQSEKTEFESES--QKLQQKLKVITELYQENEMK 390
Cdd:pfam10174 552 tnPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELESLTlrQMKEQNKKVANIKHGQQEMK 631
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 391 LHRKLTVEENYRLEKEEKLSKVDEKISHATEELETCRQRAKDLEEELERTihsyqgQVISHEKKAHdnwlaartlernLN 470
Cdd:pfam10174 632 KKGAQLLEEARRREDNLADNSQQLQLEELMGALEKTRQELDATKARLSST------QQSLAEKDGH------------LT 693
|
330 340 350
....*....|....*....|....*....|..
gi 1720372421 471 DLRKEnahNRQKLTET-EFKFELL-----EKD 496
Cdd:pfam10174 694 NLRAE---RRKQLEEIlEMKQEALlaaisEKD 722
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
308-454 |
9.42e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.45 E-value: 9.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 308 LKKLIYAAKLNASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASLQSEKTEFESESQKLQQKLKVITEL---- 383
Cdd:COG1579 6 LRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQlgnv 85
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720372421 384 -----YQ--ENEM-KLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETCRQRAKDLEEELERTIHSYQGQVISHEKK 454
Cdd:COG1579 86 rnnkeYEalQKEIeSLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAE 164
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
327-418 |
9.52e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.46 E-value: 9.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 327 ERNQVYTQLSE-VDQVKEDLTEHIKSLESKQASLQSEKTEFESESQKLQQKLKVITELYQENEMKLHR--KLTVEEnyrl 403
Cdd:PRK12704 79 ERRNELQKLEKrLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERisGLTAEE---- 154
|
90
....*....|....*
gi 1720372421 404 EKEEKLSKVDEKISH 418
Cdd:PRK12704 155 AKEILLEKVEEEARH 169
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
80-495 |
1.18e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 42.75 E-value: 1.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 80 ELSALIEEKCKLLDKVSIVQKEYEGLESSLKEASFEKESTEAQsLEATYENLEQSKSKledeillleekleeeraKHSEQ 159
Cdd:TIGR02169 407 ELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALE-IKKQEWKLEQLAAD-----------------LSKYE 468
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 160 DELMaDISKRIQSLEDESKSLKSQVAEAKTTFRIFEI-------NEERLKGAIKDALNENSQLQESQKQLLQETEMMKEq 232
Cdd:TIGR02169 469 QELY-DLKEEYDRVEKELSKLQRELAEAEAQARASEErvrggraVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAG- 546
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 233 vNDLDKQKVALEESRAQAEQALSEKESQIETLVtSLLKMKDWAAVLGE-ADDGNLDLDMksgleNTAALDNQPKGALKKL 311
Cdd:TIGR02169 547 -NRLNNVVVEDDAVAKEAIELLKRRKAGRATFL-PLNKMRDERRDLSIlSEDGVIGFAV-----DLVEFDPKYEPAFKYV 619
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 312 ---------IYAAK---LNASLKALEGE---------------RNQVYTQLSEVDQVKEdLTEHIKSLESKQASLQSEKT 364
Cdd:TIGR02169 620 fgdtlvvedIEAARrlmGKYRMVTLEGElfeksgamtggsrapRGGILFSRSEPAELQR-LRERLEGLKRELSSLQSELR 698
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 365 EFESESQKLQQKLKVITELYQENEMKLHRKLTVEENYRlekeEKLSKVDEKISHATEELETCRQRAKDLE---EELERTI 441
Cdd:TIGR02169 699 RIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLK----ERLEELEEDLSSLEQEIENVKSELKELEariEELEEDL 774
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720372421 442 HSYQGQVisHEKKAHDNWLAARTLERNLNDLRKENAHNR-------QKLTETEFKFELLEK 495
Cdd:TIGR02169 775 HKLEEAL--NDLEARLSHSRIPEIQAELSKLEEEVSRIEarlreieQKLNRLTLEKEYLEK 833
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
59-485 |
1.27e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 42.34 E-value: 1.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 59 WRGFRSIRSRF-YVGREKKLALELSALIEEKCKLLDKVSIVQKEYEGLESSLKEASFEKESTEAQSLEATYENLEQSKSK 137
Cdd:TIGR00606 556 SRHSDELTSLLgYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQ 635
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 138 ledeILLLEEKLEEERAKHSEQDELM-----ADISKRIQSLEDESKS---LKSQVAEAKTtfrifEINE--ERLKGAIKD 207
Cdd:TIGR00606 636 ----DEESDLERLKEEIEKSSKQRAMlagatAVYSQFITQLTDENQSccpVCQRVFQTEA-----ELQEfiSDLQSKLRL 706
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 208 ALNENSQLQESQKQLLQETEMM----KEQVNDLDKQKVALEESR----------AQAEQALSEKESQIETLVTSLLKMKD 273
Cdd:TIGR00606 707 APDKLKSTESELKKKEKRRDEMlglaPGRQSIIDLKEKEIPELRnklqkvnrdiQRLKNDIEEQETLLGTIMPEEESAKV 786
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 274 WAAVLGEADdgNLDLDMKSGLENTAALDNQPKGALKKLIYaAKLNASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLE 353
Cdd:TIGR00606 787 CLTDVTIME--RFQMELKDVERKIAQQAAKLQGSDLDRTV-QQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLK 863
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 354 SKQASLQSEKTEFESESQKLQQ-------KLKVITELYQENEMKLHRKLTVEENyrleKEEKLSKVDEKISHATEELETC 426
Cdd:TIGR00606 864 SKTNELKSEKLQIGTNLQRRQQfeeqlveLSTEVQSLIREIKDAKEQDSPLETF----LEKDQQEKEELISSKETSNKKA 939
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 427 RQRAKDLEEELERtIHSYQGQVISHEKKAHDNWLAARTLERN-LNDLRKENAHNRQKLTE 485
Cdd:TIGR00606 940 QDKVNDIKEKVKN-IHGYMKDIENKIQDGKDDYLKQKETELNtVNAQLEECEKHQEKINE 998
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
317-487 |
2.11e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 41.85 E-value: 2.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 317 LNASLKALEGERNQV--YTQLSEVDQVKE---------DLTEHIKSLESKQASLQSEKTEFESESQKLQQKLKVITELYQ 385
Cdd:COG1196 198 LERQLEPLERQAEKAerYRELKEELKELEaellllklrELEAELEELEAELEELEAELEELEAELAELEAELEELRLELE 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 386 ENEMKLHRKLtvEENYRLEKEekLSKVDEKISHATEEletcRQRAKDLEEELERTIHSYQGQVISHEKKAHDNWLAARTL 465
Cdd:COG1196 278 ELELELEEAQ--AEEYELLAE--LARLEQDIARLEER----RRELEERLEELEEELAELEEELEELEEELEELEEELEEA 349
|
170 180
....*....|....*....|..
gi 1720372421 466 ERNLNDLRKENAHNRQKLTETE 487
Cdd:COG1196 350 EEELEEAEAELAEAEEALLEAE 371
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
316-439 |
2.14e-03 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 41.16 E-value: 2.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 316 KLNASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASLQSEKTEFESESQKLQQKLKV-ITELYQENEMKLhRK 394
Cdd:smart00787 148 GLDENLEGLKEDYKLLMKELELLNSIKPKLRDRKDALEEELRQLKQLEDELEDCDPTELDRAKEkLKKLLQEIMIKV-KK 226
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1720372421 395 LTveenyrlEKEEKLSKVDEKISHATEELETCRQRAKDLEEELER 439
Cdd:smart00787 227 LE-------ELEEELQELESKIEDLTNKKSELNTEIAEAEKKLEQ 264
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
73-487 |
2.61e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 41.49 E-value: 2.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 73 REKKLALELSALIEEKCKLLDKVSIVQKEYEGLESSLKEASFE--KESTEAQSLEATYENLEQSKSKLEDEILLLEEKLE 150
Cdd:TIGR00618 373 QQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRtsAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQ 452
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 151 EERAKHSEQDELMADISKRIQSL---------EDESKSLKSQVA-EAKTTFRIFEINEERLKGAIKDALNENS------Q 214
Cdd:TIGR00618 453 CEKLEKIHLQESAQSLKEREQQLqtkeqihlqETRKKAVVLARLlELQEEPCPLCGSCIHPNPARQDIDNPGPltrrmqR 532
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 215 LQESQKQLLQETEMMKEQVNDLDKQKVALEESRAQAEQALSEKESQIETLVTSLLKMKDWAAVLGEADDGNLDLDMKSGL 294
Cdd:TIGR00618 533 GEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLAC 612
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 295 ENTAALDN-QPKGALKKLI-----YAAKLNASLKALEGErnqvytqlsEVDQVKEDLTEHIKSLESKQASLQSEKTEFES 368
Cdd:TIGR00618 613 EQHALLRKlQPEQDLQDVRlhlqqCSQELALKLTALHAL---------QLTLTQERVREHALSIRVLPKELLASRQLALQ 683
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 369 ESQKLQQKLKVITELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETCRQRAKDLEEELERTIhsyQGQV 448
Cdd:TIGR00618 684 KMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVL---KART 760
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 1720372421 449 ISHEKKAHDNWLAART------LERNLNDLRKENAHNRQKLTETE 487
Cdd:TIGR00618 761 EAHFNNNEEVTAALQTgaelshLAAEIQFFNRLREEDTHLLKTLE 805
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
72-423 |
2.80e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 40.66 E-value: 2.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 72 GREKKLALELSALIEEKCKLLDKVSIVQKEYEGLESSLKEASFEKESTEAQsLEATYENLEQSKskledeillleEKLEE 151
Cdd:COG4372 17 GLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEE-LEQARSELEQLE-----------EELEE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 152 ERAKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKTTFRIFEINEERLKGAIKDALNENSQLQESQKQLLQETEMMKE 231
Cdd:COG4372 85 LNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQE 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 232 QVNDLDKQKVALEESRAQAEQALSEKESQIETLVTSLLKMKDWAAVLGEADDGNLDLDMK-------SGLENTAALDNQP 304
Cdd:COG4372 165 ELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKdsleaklGLALSALLDALEL 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 305 KGALKKLIYAAKLNASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQASLQSEKTEFESESQKLQQ-------KL 377
Cdd:COG4372 245 EEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDallaallEL 324
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 1720372421 378 KVITELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEEL 423
Cdd:COG4372 325 AKKLELALAILLAELADLLQLLLVGLLDNDVLELLSKGAEAGVADG 370
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
314-487 |
2.84e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 41.46 E-value: 2.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 314 AAKLNASLKALEGE-----RNQVYTQLSEVDQVKEDLTEHIKSLESKQASLQSEKTEFESESQKLQQKLKVITELYQENE 388
Cdd:COG1196 215 YRELKEELKELEAEllllkLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 389 MKLHRkLTVEENYRLEKEEKLSKVDEKISHATEELETCRQRAKDLEEELERTIHSYQGQVISHEKKAHDNWLAARTLERN 468
Cdd:COG1196 295 AELAR-LEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373
|
170
....*....|....*....
gi 1720372421 469 LNDLRKENAHNRQKLTETE 487
Cdd:COG1196 374 LAEAEEELEELAEELLEAL 392
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
110-439 |
4.28e-03 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 40.87 E-value: 4.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 110 KEASFEKESTEAQSLEATYE--------------NLEQSKSKLEDEILLLEEKLEEERAKHSEQDELMADISKRIQSLED 175
Cdd:pfam15921 456 KNESLEKVSSLTAQLESTKEmlrkvveeltakkmTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQH 535
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 176 -------------ESKSLKSQVAEAKTTFRIFEINEE----------RLKGAIkdaLNENSQLQES---QKQLLQETEMM 229
Cdd:pfam15921 536 lknegdhlrnvqtECEALKLQMAEKDKVIEILRQQIEnmtqlvgqhgRTAGAM---QVEKAQLEKEindRRLELQEFKIL 612
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 230 KEQ-----------VNDLDKQKVALEESRAQAEQALSEKESQIETLVTSLLKMKDWAAVLGEaDDGNLDLDMKSGLENTA 298
Cdd:pfam15921 613 KDKkdakirelearVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSE-DYEVLKRNFRNKSEEME 691
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 299 ALDNQPKGALKKLIYA-AKLNASLKALEGE-----------RNQVYTQLSEVDQvkedLTEHIKSLESKQASLQSEKTEF 366
Cdd:pfam15921 692 TTTNKLKMQLKSAQSElEQTRNTLKSMEGSdghamkvamgmQKQITAKRGQIDA----LQSKIQFLEEAMTNANKEKHFL 767
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720372421 367 ESESQKLQQKLKVITElyQENEMKLHRKLTVEENYRLekEEKLSKVDEKISHATEELETCRQRAKDLEEELER 439
Cdd:pfam15921 768 KEEKNKLSQELSTVAT--EKNKMAGELEVLRSQERRL--KEKVANMEVALDKASLQFAECQDIIQRQEQESVR 836
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
343-454 |
7.49e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 39.76 E-value: 7.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 343 EDLTEHIksLESKQASLQSEKTEFESESQKLQQKLKviTELYQENEMKLhRKLTVEENYRLEKEEKLSKVDEKISHATEE 422
Cdd:PRK12704 37 EEEAKRI--LEEAKKEAEAIKKEALLEAKEEIHKLR--NEFEKELRERR-NELQKLEKRLLQKEENLDRKLELLEKREEE 111
|
90 100 110
....*....|....*....|....*....|..
gi 1720372421 423 LETCRQRAKDLEEELERTIHSYQGQVISHEKK 454
Cdd:PRK12704 112 LEKKEKELEQKQQELEKKEEELEELIEEQLQE 143
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
157-399 |
7.76e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 39.61 E-value: 7.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 157 SEQDELMADiskRIQSLEDESKSLKSQVAEAKTTFRIFEINEERLKGAIKDALNEN----SQLQESQKQLLQETEMMKEQ 232
Cdd:PHA02562 166 SEMDKLNKD---KIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKqnkyDELVEEAKTIKAEIEELTDE 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 233 VNDLDKQKVALEESRAQAEQALSEKESQIETLvTSLLKM--------------KDWAAVLGEADDGNLDLDMKSGLENTA 298
Cdd:PHA02562 243 LLNLVMDIEDPSAALNKLNTAAAKIKSKIEQF-QKVIKMyekggvcptctqqiSEGPDRITKIKDKLKELQHSLEKLDTA 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 299 ALDNQpkgalKKLIYAAKLNASLKALEGERNQVYTQLS-EVDQvkedltehIKSLESKQASLQSEKTEFESESQKLQQKL 377
Cdd:PHA02562 322 IDELE-----EIMDEFNEQSKKLLELKNKISTNKQSLItLVDK--------AKKVKAAIEELQAEFVDNAEELAKLQDEL 388
|
250 260
....*....|....*....|..
gi 1720372421 378 KVITELYQENEMKLHRKLTVEE 399
Cdd:PHA02562 389 DKIVKTKSELVKEKYHRGIVTD 410
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
201-447 |
8.78e-03 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 39.02 E-value: 8.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 201 LKGAIKDALNENSQLQESQKQ---LLQETEMMKEQVNDLDKQKVALEesrAQAEQALSEKESQIETlVTSLLKmkdwaaV 277
Cdd:pfam15905 61 LKKKSQKNLKESKDQKELEKEiraLVQERGEQDKRLQALEEELEKVE---AKLNAAVREKTSLSAS-VASLEK------Q 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 278 LGEADDGNLDLDMKSGLENTAALDNQPKGALKKLiyAAKLNASLKALEGERNQVYTQLSEVDQVKEDLTEHIKSLESKQA 357
Cdd:pfam15905 131 LLELTRVNELLKAKFSEDGTQKKMSSLSMELMKL--RNKLEAKMKEVMAKQEGMEGKLQVTQKNLEHSKGKVAQLEEKLV 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 358 SLQSEKTEFESESQKLqqkLKVITELYQENE--MKLHRKLTVEENYRLEKEEKL----SKVDEKISHATEELETCRQRAK 431
Cdd:pfam15905 209 STEKEKIEEKSETEKL---LEYITELSCVSEqvEKYKLDIAQLEELLKEKNDEIeslkQSLEEKEQELSKQIKDLNEKCK 285
|
250
....*....|....*.
gi 1720372421 432 DLEEELERTIHSYQGQ 447
Cdd:pfam15905 286 LLESEKEELLREYEEK 301
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
336-439 |
9.00e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 39.53 E-value: 9.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 336 SEVDQVKEDLTE----HIkslESKQASLQSEKT-EFESESQKLQQKLKVITELYQENEMKLHRKLTVEENyRLEK----- 405
Cdd:PRK05771 16 SYKDEVLEALHElgvvHI---EDLKEELSNERLrKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVK-SLEElikdv 91
|
90 100 110
....*....|....*....|....*....|....
gi 1720372421 406 EEKLSKVDEKISHATEELETCRQRAKDLEEELER 439
Cdd:PRK05771 92 EEELEKIEKEIKELEEEISELENEIKELEQEIER 125
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
315-455 |
9.27e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 39.12 E-value: 9.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720372421 315 AKLNASLKALEGERNQVYTQL----SEVDQVKEDLTEHIKSLESKQASLQSEKTEFESESQKLQQKLKVITELYQENEMK 390
Cdd:COG4372 48 EQLREELEQAREELEQLEEELeqarSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDL 127
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720372421 391 lhrkltveENYRLEKEEKLSKVDEKISHATEELETCRQRAKDLEEELERTIHSYQGQVISHEKKA 455
Cdd:COG4372 128 --------EQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQA 184
|
|
| |
