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Conserved domains on  [gi|1370467111|ref|XP_024305800|]
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golgin subfamily A member 8T isoform X1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GOLGA2L5 super family cl25923
Putative golgin subfamily A member 2-like protein 5; The function of the GOLGA2L5 protein ...
 213-497 2.99e-38

Putative golgin subfamily A member 2-like protein 5; The function of the GOLGA2L5 protein family remains unknown. This family of proteins is thought to be found in the Golgi apparatus of eukaryotes.


The actual alignment was detected with superfamily member pfam15070:

Pssm-ID: 464485 [Multi-domain]  Cd Length: 521  Bit Score: 148.29  E-value: 2.99e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 213 QLKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVP-- 290
Cdd:pfam15070   1 QLMESLKQLQTERDQYAENLKEEGAVWQQKMQQLSEQVRTLREEKERSVSQVQELETSLAELKNQAAVPPAEEEQPPAgp 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 291 SEVE------LQHLRKELERVAGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSL------------- 351
Cdd:pfam15070  81 SEEEqrlqeeAEQLQKELEALAGQLQAQVQDNEQLSRLNQEQEQRLLELERAAERWGEQAEDRKQILedmqsdratisra 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 352 --------QQLAKPQSVFEEPNNEN---KNALQLEQQVK--------ELQEKLGE------------------------- 387
Cdd:pfam15070 161 lsqnrelkEQLAELQNGFVKLTNENmelTSALQSEQHVKkelakklgQLQEELGElketlelksqeaqslqeqrdqylah 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 388 ------------------------------------------------------EHLEAASQQNQQLTAQLSLMALPGEG 413
Cdd:pfam15070 241 lqqyvaayqqlasekeelhkqyllqtqlmdrlqheevqgkvaaemarqelqetqERLEALTQQNQQLQAQLSLLANPGEG 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 414 HGGEHlDSEGEEAPQPMPSVPEDLESREAMSSFMDHL-----KEKADLSELVKKElcfihhwrDRRHQKTHHLLS----E 484
Cdd:pfam15070 321 DGLES-EEEEEEAPRPSLSIPEDFESREAMVAFFNSAlaqaeEERAELRRQLKEQ--------KRRCRRLAQQAApaqeE 391

                         410
                  ....*....|...
gi 1370467111 485 PGGCAKDAALGGG 497
Cdd:pfam15070 392 PEHEAHAPGTGGD 404
GM130_C pfam19046
GM130 C-terminal binding motif; This entry represents the C-terminal motif from the GM130 ...
 579-618 1.05e-14

GM130 C-terminal binding motif; This entry represents the C-terminal motif from the GM130 protein that is bound by the GRASP65 PDZ domain pfam04495.


:

Pssm-ID: 465957  Cd Length: 46  Bit Score: 68.18  E-value: 1.05e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1370467111 579 PLLDKPTAQPIV------QDHQEHPGLGSNCCVPFLCWAWLPRRRR 618
Cdd:pfam19046   1 SPPENPTAQQIMqllpeiQNPQEHPGLGSNPCIPFFYRADENDEVK 46
EnvC super family cl34844
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 73-277 2.14e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG4942:

Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.23  E-value: 2.14e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  73 LDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLryfEEKSKD 152
Cdd:COG4942    29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL---EAQKEE 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 153 LA--VRLQHSLQRKGELESVLSNVMATQKKKA----NQLSSRSKARTEwKLEQSMREETLLKVQLTQLKESFQQVQLERD 226
Cdd:COG4942   106 LAelLRALYRLGRQPPLALLLSPEDFLDAVRRlqylKYLAPARREQAE-ELRADLAELAALRAELEAERAELEALLAELE 184

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1370467111 227 EYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQ 277
Cdd:COG4942   185 EERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
 
Name Accession Description Interval E-value
GOLGA2L5 pfam15070
Putative golgin subfamily A member 2-like protein 5; The function of the GOLGA2L5 protein ...
 213-497 2.99e-38

Putative golgin subfamily A member 2-like protein 5; The function of the GOLGA2L5 protein family remains unknown. This family of proteins is thought to be found in the Golgi apparatus of eukaryotes.


Pssm-ID: 464485 [Multi-domain]  Cd Length: 521  Bit Score: 148.29  E-value: 2.99e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 213 QLKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVP-- 290
Cdd:pfam15070   1 QLMESLKQLQTERDQYAENLKEEGAVWQQKMQQLSEQVRTLREEKERSVSQVQELETSLAELKNQAAVPPAEEEQPPAgp 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 291 SEVE------LQHLRKELERVAGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSL------------- 351
Cdd:pfam15070  81 SEEEqrlqeeAEQLQKELEALAGQLQAQVQDNEQLSRLNQEQEQRLLELERAAERWGEQAEDRKQILedmqsdratisra 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 352 --------QQLAKPQSVFEEPNNEN---KNALQLEQQVK--------ELQEKLGE------------------------- 387
Cdd:pfam15070 161 lsqnrelkEQLAELQNGFVKLTNENmelTSALQSEQHVKkelakklgQLQEELGElketlelksqeaqslqeqrdqylah 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 388 ------------------------------------------------------EHLEAASQQNQQLTAQLSLMALPGEG 413
Cdd:pfam15070 241 lqqyvaayqqlasekeelhkqyllqtqlmdrlqheevqgkvaaemarqelqetqERLEALTQQNQQLQAQLSLLANPGEG 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 414 HGGEHlDSEGEEAPQPMPSVPEDLESREAMSSFMDHL-----KEKADLSELVKKElcfihhwrDRRHQKTHHLLS----E 484
Cdd:pfam15070 321 DGLES-EEEEEEAPRPSLSIPEDFESREAMVAFFNSAlaqaeEERAELRRQLKEQ--------KRRCRRLAQQAApaqeE 391

                         410
                  ....*....|...
gi 1370467111 485 PGGCAKDAALGGG 497
Cdd:pfam15070 392 PEHEAHAPGTGGD 404
GM130_C pfam19046
GM130 C-terminal binding motif; This entry represents the C-terminal motif from the GM130 ...
 579-618 1.05e-14

GM130 C-terminal binding motif; This entry represents the C-terminal motif from the GM130 protein that is bound by the GRASP65 PDZ domain pfam04495.


Pssm-ID: 465957  Cd Length: 46  Bit Score: 68.18  E-value: 1.05e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1370467111 579 PLLDKPTAQPIV------QDHQEHPGLGSNCCVPFLCWAWLPRRRR 618
Cdd:pfam19046   1 SPPENPTAQQIMqllpeiQNPQEHPGLGSNPCIPFFYRADENDEVK 46
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 67-403 1.34e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.57  E-value: 1.34e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  67 QERAVVLDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLRYF 146
Cdd:COG1196   228 ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 147 EEKSKDLAVRLQHSLQRKGELEsvlsnvmatqkkkaNQLSSRSKARTEWKLEQSMREETLLKVQLtQLKESFQQVQLERD 226
Cdd:COG1196   308 EERRRELEERLEELEEELAELE--------------EELEELEEELEELEEELEEAEEELEEAEA-ELAEAEEALLEAEA 372

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 227 EYSEHLKGERARWQQRMRKMSQEIcTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVA 306
Cdd:COG1196   373 ELAEAEEELEELAEELLEALRAAA-ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE 451

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 307 GELQAQVKKNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSLQQLAK-----PQSVFEEPNNENKN----ALQLEQQ 377
Cdd:COG1196   452 AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAdyegfLEGVKAALLLAGLRglagAVAVLIG 531

                         330       340
                  ....*....|....*....|....*.
gi 1370467111 378 VKELQEKLGEEHLEAASQQNQQLTAQ 403
Cdd:COG1196   532 VEAAYEAALEAALAAALQNIVVEDDE 557
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 67-361 5.92e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.30  E-value: 5.92e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111   67 QERAVVLDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLRYF 146
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  147 EEKSKDLAVRLQHSLQRKGELESVLsnvmaTQKKKANQLSSRSKARTEWKLEQSMREETLLKVQLTQLKESFQQV---QL 223
Cdd:TIGR02168  301 EQQKQILRERLANLERQLEELEAQL-----EELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELesrLE 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  224 ERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKL-----KNQMAEPLPPEPPAVPSEVELQHL 298
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELlkkleEAELKELQAELEELEEELEELQEE 455

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1370467111  299 RKELERVAGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSLQQLAKPQSVF 361
Cdd:TIGR02168  456 LERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGL 518
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 73-277 2.14e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.23  E-value: 2.14e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  73 LDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLryfEEKSKD 152
Cdd:COG4942    29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL---EAQKEE 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 153 LA--VRLQHSLQRKGELESVLSNVMATQKKKA----NQLSSRSKARTEwKLEQSMREETLLKVQLTQLKESFQQVQLERD 226
Cdd:COG4942   106 LAelLRALYRLGRQPPLALLLSPEDFLDAVRRlqylKYLAPARREQAE-ELRADLAELAALRAELEAERAELEALLAELE 184

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1370467111 227 EYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQ 277
Cdd:COG4942   185 EERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
PRK11281 PRK11281
mechanosensitive channel MscK;
203-403 1.02e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.21  E-value: 1.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  203 EETLLKVQLTQLKESFQQVQLERDEySEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRR------VEELERSLSKLKN 276
Cdd:PRK11281    57 EDKLVQQDLEQTLALLDKIDRQKEE-TEQLKQQLAQAPAKLRQAQAELEALKDDNDEETREtlstlsLRQLESRLAQTLD 135

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  277 QMAEPLPPEPPAVPSEVELQhlrKELERVAGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQ--------EERIQEQH 348
Cdd:PRK11281   136 QLQNAQNDLAEYNSQLVSLQ---TQPERAQAALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLlqaeqallNAQNDLQR 212

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370467111  349 KSLQQLAKPQSVFEEPNNE-NKNALQLEQQVKELQEKLGEEHLEAASQQNQQLTAQ 403
Cdd:PRK11281   213 KSLEGNTQLQDLLQKQRDYlTARIQRLEHQLQLLQEAINSKRLTLSEKTVQEAQSQ 268
 
Name Accession Description Interval E-value
GOLGA2L5 pfam15070
Putative golgin subfamily A member 2-like protein 5; The function of the GOLGA2L5 protein ...
 213-497 2.99e-38

Putative golgin subfamily A member 2-like protein 5; The function of the GOLGA2L5 protein family remains unknown. This family of proteins is thought to be found in the Golgi apparatus of eukaryotes.


Pssm-ID: 464485 [Multi-domain]  Cd Length: 521  Bit Score: 148.29  E-value: 2.99e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 213 QLKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVP-- 290
Cdd:pfam15070   1 QLMESLKQLQTERDQYAENLKEEGAVWQQKMQQLSEQVRTLREEKERSVSQVQELETSLAELKNQAAVPPAEEEQPPAgp 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 291 SEVE------LQHLRKELERVAGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSL------------- 351
Cdd:pfam15070  81 SEEEqrlqeeAEQLQKELEALAGQLQAQVQDNEQLSRLNQEQEQRLLELERAAERWGEQAEDRKQILedmqsdratisra 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 352 --------QQLAKPQSVFEEPNNEN---KNALQLEQQVK--------ELQEKLGE------------------------- 387
Cdd:pfam15070 161 lsqnrelkEQLAELQNGFVKLTNENmelTSALQSEQHVKkelakklgQLQEELGElketlelksqeaqslqeqrdqylah 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 388 ------------------------------------------------------EHLEAASQQNQQLTAQLSLMALPGEG 413
Cdd:pfam15070 241 lqqyvaayqqlasekeelhkqyllqtqlmdrlqheevqgkvaaemarqelqetqERLEALTQQNQQLQAQLSLLANPGEG 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 414 HGGEHlDSEGEEAPQPMPSVPEDLESREAMSSFMDHL-----KEKADLSELVKKElcfihhwrDRRHQKTHHLLS----E 484
Cdd:pfam15070 321 DGLES-EEEEEEAPRPSLSIPEDFESREAMVAFFNSAlaqaeEERAELRRQLKEQ--------KRRCRRLAQQAApaqeE 391

                         410
                  ....*....|...
gi 1370467111 485 PGGCAKDAALGGG 497
Cdd:pfam15070 392 PEHEAHAPGTGGD 404
GM130_C pfam19046
GM130 C-terminal binding motif; This entry represents the C-terminal motif from the GM130 ...
 579-618 1.05e-14

GM130 C-terminal binding motif; This entry represents the C-terminal motif from the GM130 protein that is bound by the GRASP65 PDZ domain pfam04495.


Pssm-ID: 465957  Cd Length: 46  Bit Score: 68.18  E-value: 1.05e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1370467111 579 PLLDKPTAQPIV------QDHQEHPGLGSNCCVPFLCWAWLPRRRR 618
Cdd:pfam19046   1 SPPENPTAQQIMqllpeiQNPQEHPGLGSNPCIPFFYRADENDEVK 46
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 67-403 1.34e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.57  E-value: 1.34e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  67 QERAVVLDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLRYF 146
Cdd:COG1196   228 ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 147 EEKSKDLAVRLQHSLQRKGELEsvlsnvmatqkkkaNQLSSRSKARTEWKLEQSMREETLLKVQLtQLKESFQQVQLERD 226
Cdd:COG1196   308 EERRRELEERLEELEEELAELE--------------EELEELEEELEELEEELEEAEEELEEAEA-ELAEAEEALLEAEA 372

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 227 EYSEHLKGERARWQQRMRKMSQEIcTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVA 306
Cdd:COG1196   373 ELAEAEEELEELAEELLEALRAAA-ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE 451

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 307 GELQAQVKKNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSLQQLAK-----PQSVFEEPNNENKN----ALQLEQQ 377
Cdd:COG1196   452 AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAdyegfLEGVKAALLLAGLRglagAVAVLIG 531

                         330       340
                  ....*....|....*....|....*.
gi 1370467111 378 VKELQEKLGEEHLEAASQQNQQLTAQ 403
Cdd:COG1196   532 VEAAYEAALEAALAAALQNIVVEDDE 557
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 67-361 5.92e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 59.30  E-value: 5.92e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111   67 QERAVVLDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLRYF 146
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  147 EEKSKDLAVRLQHSLQRKGELESVLsnvmaTQKKKANQLSSRSKARTEWKLEQSMREETLLKVQLTQLKESFQQV---QL 223
Cdd:TIGR02168  301 EQQKQILRERLANLERQLEELEAQL-----EELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELesrLE 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  224 ERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKL-----KNQMAEPLPPEPPAVPSEVELQHL 298
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELlkkleEAELKELQAELEELEEELEELQEE 455

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1370467111  299 RKELERVAGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSLQQLAKPQSVF 361
Cdd:TIGR02168  456 LERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGL 518
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 84-442 6.44e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.83  E-value: 6.44e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111   84 KNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQR 163
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE 755

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  164 KGELEsvlsnvmatqKKKANQLSSRSKARTEWKLeqsmreetlLKVQLTQLKESFQQVQLERDEYSEHLKGERARWQQrm 243
Cdd:TIGR02168  756 LTELE----------AEIEELEERLEEAEEELAE---------AEAEIEELEAQIEQLKEELKALREALDELRAELTL-- 814

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  244 rkmsqeictLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKKNQrislln 323
Cdd:TIGR02168  815 ---------LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALL------ 879

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  324 qrqeeriqeqeERLRKQEERIQEQHKSLQQLAkpqsvfEEPNNENKNALQLEQQVKELQEKLG--EEHLEAASQQNQQLT 401
Cdd:TIGR02168  880 -----------NERASLEEALALLRSELEELS------EELRELESKRSELRRELEELREKLAqlELRLEGLEVRIDNLQ 942

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|.
gi 1370467111  402 AQLSlmalpgeghggEHLDSEGEEAPQPMPSVPEDLESREA 442
Cdd:TIGR02168  943 ERLS-----------EEYSLTLEEAEALENKIEDDEEEARR 972
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 73-277 2.14e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.23  E-value: 2.14e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  73 LDSRSVEISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLryfEEKSKD 152
Cdd:COG4942    29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL---EAQKEE 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 153 LA--VRLQHSLQRKGELESVLSNVMATQKKKA----NQLSSRSKARTEwKLEQSMREETLLKVQLTQLKESFQQVQLERD 226
Cdd:COG4942   106 LAelLRALYRLGRQPPLALLLSPEDFLDAVRRlqylKYLAPARREQAE-ELRADLAELAALRAELEAERAELEALLAELE 184

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1370467111 227 EYSEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQ 277
Cdd:COG4942   185 EERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 118-406 4.59e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.02  E-value: 4.59e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 118 LEVQIQTLNIQKE------ELNTDLYHMKRSLRYFEEKskDLAVRLQHSLQRKGELESVLSNVMATQKKKANQLSSRSKA 191
Cdd:COG1196   198 LERQLEPLERQAEkaeryrELKEELKELEAELLLLKLR--ELEAELEELEAELEELEAELEELEAELAELEAELEELRLE 275

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 192 RTE--WKLEQSMREETLLKVQLTQLKESFQQVQLERDEYS---EHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEE 266
Cdd:COG1196   276 LEEleLELEEAQAEEYELLAELARLEQDIARLEERRRELEerlEELEEELAELEEELEELEEELEELEEELEEAEEELEE 355

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 267 LERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKKNQRisllnqrQEERIQEQEERLRKQEERIQE 346
Cdd:COG1196   356 AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE-------AEEALLERLERLEEELEELEE 428

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 347 QHKSLQQLAKPQSVFEEpnNENKNALQLEQQVKELQEKLGEEHLEAASQQNQQLTAQLSL 406
Cdd:COG1196   429 ALAELEEEEEEEEEALE--EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 87-404 8.52e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 52.37  E-value: 8.52e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111   87 IKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEElnTDLYHMKRSlryfEEKSKDLAVRLQHSLQRKGE 166
Cdd:TIGR02168  167 ISKYKERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEK--AERYKELKA----ELRELELALLVLRLEELREE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  167 LESVLSNVMATQKKKaNQLSSRSKARTEwKLEQSMREETLLKVQLTQLKESFQQVQLERDEysehLKGERARWQQRMRKM 246
Cdd:TIGR02168  241 LEELQEELKEAEEEL-EELTAELQELEE-KLEELRLEVSELEEEIEELQKELYALANEISR----LEQQKQILRERLANL 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  247 SQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKKNQRISLLNQRQ 326
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQ 394

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370467111  327 EERIQEQEERLRKQEERIQEQHKSLQQLAKPQSVFEEPNNENKNALQLEQQVKELQEKlgEEHLEAASQQNQQLTAQL 404
Cdd:TIGR02168  395 IASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEEL--QEELERLEEALEELREEL 470
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 85-278 8.29e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 8.29e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  85 NTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRK 164
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 165 GELESVLSNVMATQKKKANQ------LSSRSKARTEWKLE----------QSMREETLLKVQLTQLKESFQQVQLERDEY 228
Cdd:COG4942   100 EAQKEELAELLRALYRLGRQpplallLSPEDFLDAVRRLQylkylaparrEQAEELRADLAELAALRAELEAERAELEAL 179

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1370467111 229 SEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQM 278
Cdd:COG4942   180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALI 229
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 144-462 1.65e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.14  E-value: 1.65e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  144 RYFEEKSKDLAVRLQhSLQRkgELESVLSNVmATQKKKANQLSSRSKARTEwKLEQSMREETLLKVQLTQLKEsfQQVQL 223
Cdd:TIGR02169  670 RSEPAELQRLRERLE-GLKR--ELSSLQSEL-RRIENRLDELSQELSDASR-KIGEIEKEIEQLEQEEEKLKE--RLEEL 742

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  224 ERDeysehlkgerarwqqrMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEV--ELQHLRKE 301
Cdd:TIGR02169  743 EED----------------LSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIqaELSKLEEE 806

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  302 LERVAGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQEERI----QEQHKSLQQLAKPQSVFEEPNNE---------- 367
Cdd:TIGR02169  807 VSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIksieKEIENLNGKKEELEEELEELEAAlrdlesrlgd 886

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  368 -NKNALQLEQQVKELQEKLGE--EHLEAASQQNQQLTAQLSlmALPGEGHGGEHLDSEGEEAPQPMPSVPEDLESREAMS 444
Cdd:TIGR02169  887 lKKERDELEAQLRELERKIEEleAQIEKKRKRLSELKAKLE--ALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVE 964

                          330       340       350
                   ....*....|....*....|....*....|
gi 1370467111  445 SFMDHL------------KEKADLSELVKK 462
Cdd:TIGR02169  965 EEIRALepvnmlaiqeyeEVLKRLDELKEK 994
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
100-411 2.41e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 2.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 100 QLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLRyfeekSKDLAVRLQHSLQRKGELESVLSNVMAtqk 179
Cdd:COG4717    75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE-----KLEKLLQLLPLYQELEALEAELAELPE--- 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 180 kKANQLSSRSKARTEWKLEQSMREETLLKVQlTQLKESFQQVQLERDEYSEHLKGERARWQQRMRKMSQEICTLKKEKQQ 259
Cdd:COG4717   147 -RLEELEERLEELRELEEELEELEAELAELQ-EELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEE 224

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 260 DMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEV-----ELQHLRKELERVAGELQAQVKKNQRISLLNQRQEERIQEQE 334
Cdd:COG4717   225 LEEELEQLENELEAAALEERLKEARLLLLIAAALlallgLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEA 304

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370467111 335 ERLRKQEERIQEQHKSLQQLAKPQSVfeEPNNENKNALQLEQQVKELQEKLGE-EHLEAASQQNQQLTAQLSLMALPG 411
Cdd:COG4717   305 EELQALPALEELEEEELEELLAALGL--PPDLSPEELLELLDRIEELQELLREaEELEEELQLEELEQEIAALLAEAG 380
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 79-404 3.58e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.47  E-value: 3.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  79 EISQLKNTIKSLKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTD-----LYHMKRSLRYFEEKSKDL 153
Cdd:TIGR04523 247 EISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQkeqdwNKELKSELKNQEKKLEEI 326

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 154 AVRLQHSLQRKGELESVLSNVmatQKKKANQLSSRSKARTEwkLEQSMREETLLKVQLTQLKESFQQVQLERDEysehLK 233
Cdd:TIGR04523 327 QNQISQNNKIISQLNEQISQL---KKELTNSESENSEKQRE--LEEKQNEIEKLKKENQSYKQEIKNLESQIND----LE 397

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 234 GERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQV 313
Cdd:TIGR04523 398 SKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSI 477

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 314 KKNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSLQQlaKPQSVFEEPNNENKNALQLEQQVKELQEKLGE------ 387
Cdd:TIGR04523 478 NKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTK--KISSLKEKIEKLESEKKEKESKISDLEDELNKddfelk 555

                         330
                  ....*....|....*...
gi 1370467111 388 -EHLEAASQQNQQLTAQL 404
Cdd:TIGR04523 556 kENLEKEIDEKNKEIEEL 573
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 90-455 5.61e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.17  E-value: 5.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  90 LKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKEELNTDLYHMKRSLRYFEEKSKDLAVRLQHSLQRKGELES 169
Cdd:pfam05483 217 LKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTK 296

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 170 VLSNVmatqkkkanQLSSRSKARTEWKLEQSMREETLLKVQLTQLKESfqqvqlerdeYSEHLKGERARWQQRMRKMSQE 249
Cdd:pfam05483 297 ELEDI---------KMSLQRSMSTQKALEEDLQIATKTICQLTEEKEA----------QMEELNKAKAAHSFVVTEFEAT 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 250 ICTLKKEKQQDMRRVEELERSLS----KLKNQMAEPLPPEPPAVPSEVELQhlrkELERVAGELQAQVKKNQRISLLNQR 325
Cdd:pfam05483 358 TCSLEELLRTEQQRLEKNEDQLKiitmELQKKSSELEEMTKFKNNKEVELE----ELKKILAEDEKLLDEKKQFEKIAEE 433

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 326 QEERIQEQEERLRKQEERIQEQHKSLQQLAKPQSVFEEPNNENKNALQLEQqvkeLQEKLGEEHLEAASQQNQQLTAQLS 405
Cdd:pfam05483 434 LKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEK----LKNIELTAHCDKLLLENKELTQEAS 509

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1370467111 406 LMALPGEGHGGEHLDSEGEEapQPMPSVPEDLES-----REAMSSFMDHLKEKAD 455
Cdd:pfam05483 510 DMTLELKKHQEDIINCKKQE--ERMLKQIENLEEkemnlRDELESVREEFIQKGD 562
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
179-409 8.82e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 8.82e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 179 KKKANQLSSRSKARTEWKLEQSMREETLLKvQLTQLKESFQQVQLERDEYS---EHLKGERARWQQRMRKMSQEIctlkk 255
Cdd:COG4717    52 EKEADELFKPQGRKPELNLKELKELEEELK-EAEEKEEEYAELQEELEELEeelEELEAELEELREELEKLEKLL----- 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 256 EKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVkknQRISLLNQRQEERIQEQEE 335
Cdd:COG4717   126 QLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELL---EQLSLATEEELQDLAEELE 202

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370467111 336 RLRKQEERIQEQHKSLQQLAKpqsvfeepnnenknalQLEQQVKELQEKLGEEHLEAASQQNQQLTAQLSLMAL 409
Cdd:COG4717   203 ELQQRLAELEEELEEAQEELE----------------ELEEELEQLENELEAAALEERLKEARLLLLIAAALLA 260
PRK11281 PRK11281
mechanosensitive channel MscK;
203-403 1.02e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.21  E-value: 1.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  203 EETLLKVQLTQLKESFQQVQLERDEySEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRR------VEELERSLSKLKN 276
Cdd:PRK11281    57 EDKLVQQDLEQTLALLDKIDRQKEE-TEQLKQQLAQAPAKLRQAQAELEALKDDNDEETREtlstlsLRQLESRLAQTLD 135

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  277 QMAEPLPPEPPAVPSEVELQhlrKELERVAGELQAQVKKNQRISLLNQRQEERIQEQEERLRKQ--------EERIQEQH 348
Cdd:PRK11281   136 QLQNAQNDLAEYNSQLVSLQ---TQPERAQAALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLlqaeqallNAQNDLQR 212

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370467111  349 KSLQQLAKPQSVFEEPNNE-NKNALQLEQQVKELQEKLGEEHLEAASQQNQQLTAQ 403
Cdd:PRK11281   213 KSLEGNTQLQDLLQKQRDYlTARIQRLEHQLQLLQEAINSKRLTLSEKTVQEAQSQ 268
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
156-391 1.85e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.59  E-value: 1.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 156 RLQHSLQRKGELESVLSNVMATQKKKANQLSSRSKARTEWKLEQSMREETLLKvqLTQLKESFQQVQLERDEYSEHLKGE 235
Cdd:PRK03918  180 RLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKE--LEELKEEIEELEKELESLEGSKRKL 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 236 RARWQQRMRKMsqeictlkKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKK 315
Cdd:PRK03918  258 EEKIRELEERI--------EELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEER 329

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370467111 316 NQRISllnqrqeeriqeqeerlrKQEERIQEQHKSLQQLAKPQSVFEEPNNENKNALQLEQQVKELQEKLGEEHLE 391
Cdd:PRK03918  330 IKELE------------------EKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPE 387
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 161-403 3.06e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 40.49  E-value: 3.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 161 LQRKGELESVLSNVMATQKKKANQLSSRSKARTEWKLEQSMREETLLKVQLTQLKESFQQVQLERDEYSEHLKGERARWQ 240
Cdd:pfam17380 312 VERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEEIAMEISRMRELERLQMERQQKN 391

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 241 QRMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPAVPSEVElqhlrKELERVAGELQAQVKKNQRIs 320
Cdd:pfam17380 392 ERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERA-----REMERVRLEEQERQQQVERL- 465

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 321 llnqrqeerIQEQEERLRKQEERIQEQHKSLQQLAKPQSVFEEPNNENKNALQLEQQVKELQEKLGEEHLEAASQQNQQL 400
Cdd:pfam17380 466 ---------RQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRR 536


                  ...
gi 1370467111 401 TAQ 403
Cdd:pfam17380 537 EAE 539
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 232-405 6.01e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 39.36  E-value: 6.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 232 LKGERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPA----VPSEVELQHLRKELERVAG 307
Cdd:COG4942    25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALeaelAELEKEIAELRAELEAQKE 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 308 ELQAQVKKNQRIS-------LLNQRQEERIQEQEERL-------RKQEERIQEQHKSLQQLAKPQsvfeepnneNKNALQ 373
Cdd:COG4942   105 ELAELLRALYRLGrqpplalLLSPEDFLDAVRRLQYLkylaparREQAEELRADLAELAALRAEL---------EAERAE 175

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1370467111 374 LEQQVKELQEKLGEehLEAASQQNQQLTAQLS 405
Cdd:COG4942   176 LEALLAELEEERAA--LEALKAERQKLLARLE 205
PTZ00121 PTZ00121
MAEBL; Provisional
 147-368 6.39e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 39.74  E-value: 6.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  147 EEKSKDLAVRLQHSLQR--KGELESVLSNVMATQKKKANQL----SSRSKARTEWKLEQSMREETLLKVQLTQLKESFQQ 220
Cdd:PTZ00121  1572 AEEDKNMALRKAEEAKKaeEARIEEVMKLYEEEKKMKAEEAkkaeEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEE 1651

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  221 V------------QLERDEYSEHLKGERARWQQRMRKMSQEictLKKEKQQDMRRVEELERSLSKLKNQMAEPLPPEPPA 288
Cdd:PTZ00121  1652 LkkaeeenkikaaEEAKKAEEDKKKAEEAKKAEEDEKKAAE---ALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEEN 1728

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111  289 VPSEVELQHLRKELERVAGELQ---------AQVKKNQRISLLNQRQEERIQEQEERLRKQEERIQEQHKSLQQLAKPQS 359
Cdd:PTZ00121  1729 KIKAEEAKKEAEEDKKKAEEAKkdeeekkkiAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFA 1808


                   ....*....
gi 1370467111  360 VFEEPNNEN 368
Cdd:PTZ00121  1809 NIIEGGKEG 1817
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 148-406 8.97e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 38.59  E-value: 8.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 148 EKSKDLAVRLQHSLQRKGELESVLSNVMATQKKKANQLSSRSK--ARTEWKLEQSMREETLLKVQLTQLKESFQQVQLER 225
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERriAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 226 DEYSEHLKgERARWQQRMRKMSQEICTLKKEKQQDMRRVEELERSLSK-LKNQMAeplppeppavpsevELQHLRKELER 304
Cdd:COG4942   100 EAQKEELA-ELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPaRREQAE--------------ELRADLAELAA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370467111 305 VAGELQAQVKKNQRIsllnqrqeerIQEQEERLRKQEERIQEQHKSLQQLAKPQSVFEEPNNE-NKNALQLEQQVKELQE 383
Cdd:COG4942   165 LRAELEAERAELEAL----------LAELEEERAALEALKAERQKLLARLEKELAELAAELAElQQEAEELEALIARLEA 234

                         250       260
                  ....*....|....*....|...
gi 1370467111 384 KLGEEHLEAASQQNQQLTAQLSL 406
Cdd:COG4942   235 EAAAAAERTPAAGFAALKGKLPW 257
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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