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Conserved domains on  [gi|1005957665|ref|XP_015787237|]
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mediator of RNA polymerase II transcription subunit 23 [Tetranychus urticae]

Protein Classification

Med23 domain-containing protein( domain architecture ID 10569018)

Med23 domain-containing protein

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Med23 pfam11573
Mediator complex subunit 23; Med23 is one of the subunits of the Tail portion of the Mediator ...
 10-1309 0e+00

Mediator complex subunit 23; Med23 is one of the subunits of the Tail portion of the Mediator complex that regulates RNA polymerase II activity. Med23 is required for heat-shock-specific gene expression, and has been shown to mediate transcriptional activation of E1A in mice.


:

Pssm-ID: 463299  Cd Length: 1301  Bit Score: 1996.47  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665   10 TVSDVHNFIDSILRTEELEAIFTGYIVESSVNEECKIKNYEEQMTALIKSCdTPEKIELMLRDYLNGAGSIPNVNKVRLL 89
Cdd:pfam11573    1 EVNQVKSIINEILKVEIIEEAFSGFTSNLPDDEKEKTAILRKQFNNMMSKM-SEEEKESLVKELIKLVHHVAEKNRLDFL 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665   90 LSMLEHAINNHLLSAKSVCEAILNCEHLHINKQIFFCQSFELIHRVISQVDYKGVRDIIRFMIEKIHTIPIEANIAMLPQ 169
Cdd:pfam11573   80 FQLLEYAVQKGIISARLVCEGLIMSEKLVLCNRLFWQECFKLIRKIIPGVDYKGVREILKYCLEKARRLPYSLSPEKVPQ 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  170 LDVMRKVLDYALNRNSSLLPAYLAFDEIKKK---SDKWMHWKFADLFSAFVESFRPVAQMVSIINRSKLLPIV---GYSS 243
Cdd:pfam11573  160 LRALENVILYILDRNACLLPAYFIVNEIMKGypdAKMWPHWRLAELLSNFVESFRPIAQMVSIIGRSFMLPVVehsGYAD 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  244 TLNQSWQLNAATAAFDLKGLLPYNNELTRPQIGLLRYVLEQPYSREMIYFMLSLTNKAKSRCPILEEQLVALIVLAMEKS 323
Cdd:pfam11573  240 HLTSPWKLDPATLKFQLKGNLPYRPELLEPQTYLLRYVLEQPYSRDMVCSMLGLQKQHKQRCKALEEQLVELMICAMERS 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  324 ENEtnnqeDTDYSQTQCLWQILSGHLITFIILNHISFPQLVRSLHESLAARNSKKGRDHLMWMLLQYISGSIQKTPLTDF 403
Cdd:pfam11573  320 ETE-----PEDEPITHWLWLHLSSQLIYFVLFQFASFPNIVKSLHEKLAGRDLTRGRDHLMWVLLQFISGSIQKNPLSDF 394

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  404 LPFFKLHDLLYPEKDPLPVPDITKPICTHTFAISSIWIHLLKKAENEPQKMIRPIPNCLRLHVEFLHQTFMSSDLP-ASL 482
Cdd:pfam11573  395 LPILKLYDLLYPEKEPLPVPDYNKPLCTHQMAATCIWIHLLKKAQDENQKLQRPIPDTLKSHHEFLQHLVLNNDSPnLAM 474

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  483 TVDSKIPLICNAYSTNSDYYNRILTILCDTIKCNSRSGSTGGNTNGAIIPLSVSLLDSVTLHTKMSLISNIVAQINKSSS 562
Cdd:pfam11573  475 GSDYRIALLCNAYSTNTEYFSRPMPALVETILGNSKSRSPGCNAPGPTTPLSMEFLDSLTVHSKMSLIHSIVTHVIKFAQ 554

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  563 KDGTI-ISPALAETYSRLLIYIELETLGIKNFIQQVIPNAIRTQSWGTLNILFEMFIHRLHHIPAPYRVQFLNQLHYLAN 641
Cdd:pfam11573  555 SKSSVaLAPALVETYSRLLVYTEIESLGIKGFISQLLPTVFKSQAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAN 634

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  642 SPHSNQIQLHSCMESTALKLITGFTSEQVLliTQLNRYQNEPKI-RISHDSEELNKVLILTLARAIHVTGCDTLIE-WCK 719
Cdd:pfam11573  635 VPQTNQTQLHLCVESTALRLITGLGSSEVQ--PQLSRFLNEPKTfLVSQESEELNRALILTLARAIHITGTGTDSEsWCK 712

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  720 ELLSNIMNSTPLAWSSCTLKCFPPAITEYYQNFNTVTENKAQLKQSVEEEYRKWITMSNENDIIAHFSIQGTPPLFLCLL 799
Cdd:pfam11573  713 ELLETIMQNTPHGWPQHTLSCFPPWLLEFFKQNNVPKENKQQLKKNVEEEYRKWTSMTNENDIIAHFSVPGTPPLFLCLL 792

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  800 WKMILENDRINPIAYKILDRIGAKALSSHLRILVDYLVNEFTNLCGTQNVTKYIDKLNDLIWKSHVITLDRLLLCLTLRA 879
Cdd:pfam11573  793 WKMLLETDRITPIAYKVLERIGARALSAHLRKFCDYLVFEFTNSCGGQHVNKCADALNDMIWKYNIVTIDRLVLCLALRP 872

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  880 YEGNEAQVSLFIIQMLLLKTTDFSNRVADFVREMSPEHWKQSNWHEKHHALHRKYPEKFYFEGLADISgqNMQHSYLPTY 959
Cdd:pfam11573  873 QEGNEAQVCFFIIQLLLLKTTEFRNRVQDFVKENSPEHWKQPNWHEKHLAYHRKFPEKFAPEGVAEYD--SSSNPYLPTY 950

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  960 FSNICLRFIPVLDLIIHRYLELPPGSPSplIDSLLEKYGCLYKFHDRPLTYLYETLHYYEHKMRERPALRRKLVSIIIGA 1039
Cdd:pfam11573  951 FGNVCLRFLPVLDIVIHRALELPPVSKS--LETLLEHLGCLYKFHDRPVTYLYNTLHYYEHKLRDRPDLKRKLVSAIIGS 1028

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665 1040 FKDIKPANWAVTDAYLNYMKRPVED-LAWNPElDYYFKLISRVVDTFQGKSP--FPHVDWRFNEFANAGVHALHITCIEL 1116
Cdd:pfam11573 1029 LKDCRPPGWALTEAYEKYHQKSSDEqLIWLPE-DYYMKLIDRMVDTMDGKTPppFPAKDWRFNEFPNPGAHALYVTCVEL 1107

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665 1117 MALPVAANVVANNLIDLVVVGHKYIPRNTIEFWNNAIGVVLTALPEAYWSVINDRIISMMESPLLTYSPHP-EPFQMMNF 1195
Cdd:pfam11573 1108 MALPVSPETVANALIDVVQKGYHLIPRNQIHLWINAIGLILTALPESYWSVLHDRIVEVLSNPELTNWTYPcSPFELFNF 1187

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665 1196 SDSHKSMSEMQPSYLIALIHSFFHHASIGQITPIPQFLRERVKPIIKTEEQFLFIVHIVCPFLQRLYAERTRRAMEVTIE 1275
Cdd:pfam11573 1188 DNYHESLLENRASYILALAHAVWHHAGIGQLNPFPQFVKEKLLPHVKTEEQLLYLCHLVGPFLQRFRAERERGVLDITKL 1267

                         1290      1300      1310
                   ....*....|....*....|....*....|....
gi 1005957665 1276 LYSFLEVIDKNCTELRFMDTITDLLYHMKYHITG 1309
Cdd:pfam11573 1268 LYELLEQVDKEGVELRYMDPICDLLYHIKYMFVG 1301
 
Name Accession Description Interval E-value
Med23 pfam11573
Mediator complex subunit 23; Med23 is one of the subunits of the Tail portion of the Mediator ...
 10-1309 0e+00

Mediator complex subunit 23; Med23 is one of the subunits of the Tail portion of the Mediator complex that regulates RNA polymerase II activity. Med23 is required for heat-shock-specific gene expression, and has been shown to mediate transcriptional activation of E1A in mice.


Pssm-ID: 463299  Cd Length: 1301  Bit Score: 1996.47  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665   10 TVSDVHNFIDSILRTEELEAIFTGYIVESSVNEECKIKNYEEQMTALIKSCdTPEKIELMLRDYLNGAGSIPNVNKVRLL 89
Cdd:pfam11573    1 EVNQVKSIINEILKVEIIEEAFSGFTSNLPDDEKEKTAILRKQFNNMMSKM-SEEEKESLVKELIKLVHHVAEKNRLDFL 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665   90 LSMLEHAINNHLLSAKSVCEAILNCEHLHINKQIFFCQSFELIHRVISQVDYKGVRDIIRFMIEKIHTIPIEANIAMLPQ 169
Cdd:pfam11573   80 FQLLEYAVQKGIISARLVCEGLIMSEKLVLCNRLFWQECFKLIRKIIPGVDYKGVREILKYCLEKARRLPYSLSPEKVPQ 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  170 LDVMRKVLDYALNRNSSLLPAYLAFDEIKKK---SDKWMHWKFADLFSAFVESFRPVAQMVSIINRSKLLPIV---GYSS 243
Cdd:pfam11573  160 LRALENVILYILDRNACLLPAYFIVNEIMKGypdAKMWPHWRLAELLSNFVESFRPIAQMVSIIGRSFMLPVVehsGYAD 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  244 TLNQSWQLNAATAAFDLKGLLPYNNELTRPQIGLLRYVLEQPYSREMIYFMLSLTNKAKSRCPILEEQLVALIVLAMEKS 323
Cdd:pfam11573  240 HLTSPWKLDPATLKFQLKGNLPYRPELLEPQTYLLRYVLEQPYSRDMVCSMLGLQKQHKQRCKALEEQLVELMICAMERS 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  324 ENEtnnqeDTDYSQTQCLWQILSGHLITFIILNHISFPQLVRSLHESLAARNSKKGRDHLMWMLLQYISGSIQKTPLTDF 403
Cdd:pfam11573  320 ETE-----PEDEPITHWLWLHLSSQLIYFVLFQFASFPNIVKSLHEKLAGRDLTRGRDHLMWVLLQFISGSIQKNPLSDF 394

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  404 LPFFKLHDLLYPEKDPLPVPDITKPICTHTFAISSIWIHLLKKAENEPQKMIRPIPNCLRLHVEFLHQTFMSSDLP-ASL 482
Cdd:pfam11573  395 LPILKLYDLLYPEKEPLPVPDYNKPLCTHQMAATCIWIHLLKKAQDENQKLQRPIPDTLKSHHEFLQHLVLNNDSPnLAM 474

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  483 TVDSKIPLICNAYSTNSDYYNRILTILCDTIKCNSRSGSTGGNTNGAIIPLSVSLLDSVTLHTKMSLISNIVAQINKSSS 562
Cdd:pfam11573  475 GSDYRIALLCNAYSTNTEYFSRPMPALVETILGNSKSRSPGCNAPGPTTPLSMEFLDSLTVHSKMSLIHSIVTHVIKFAQ 554

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  563 KDGTI-ISPALAETYSRLLIYIELETLGIKNFIQQVIPNAIRTQSWGTLNILFEMFIHRLHHIPAPYRVQFLNQLHYLAN 641
Cdd:pfam11573  555 SKSSVaLAPALVETYSRLLVYTEIESLGIKGFISQLLPTVFKSQAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAN 634

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  642 SPHSNQIQLHSCMESTALKLITGFTSEQVLliTQLNRYQNEPKI-RISHDSEELNKVLILTLARAIHVTGCDTLIE-WCK 719
Cdd:pfam11573  635 VPQTNQTQLHLCVESTALRLITGLGSSEVQ--PQLSRFLNEPKTfLVSQESEELNRALILTLARAIHITGTGTDSEsWCK 712

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  720 ELLSNIMNSTPLAWSSCTLKCFPPAITEYYQNFNTVTENKAQLKQSVEEEYRKWITMSNENDIIAHFSIQGTPPLFLCLL 799
Cdd:pfam11573  713 ELLETIMQNTPHGWPQHTLSCFPPWLLEFFKQNNVPKENKQQLKKNVEEEYRKWTSMTNENDIIAHFSVPGTPPLFLCLL 792

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  800 WKMILENDRINPIAYKILDRIGAKALSSHLRILVDYLVNEFTNLCGTQNVTKYIDKLNDLIWKSHVITLDRLLLCLTLRA 879
Cdd:pfam11573  793 WKMLLETDRITPIAYKVLERIGARALSAHLRKFCDYLVFEFTNSCGGQHVNKCADALNDMIWKYNIVTIDRLVLCLALRP 872

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  880 YEGNEAQVSLFIIQMLLLKTTDFSNRVADFVREMSPEHWKQSNWHEKHHALHRKYPEKFYFEGLADISgqNMQHSYLPTY 959
Cdd:pfam11573  873 QEGNEAQVCFFIIQLLLLKTTEFRNRVQDFVKENSPEHWKQPNWHEKHLAYHRKFPEKFAPEGVAEYD--SSSNPYLPTY 950

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  960 FSNICLRFIPVLDLIIHRYLELPPGSPSplIDSLLEKYGCLYKFHDRPLTYLYETLHYYEHKMRERPALRRKLVSIIIGA 1039
Cdd:pfam11573  951 FGNVCLRFLPVLDIVIHRALELPPVSKS--LETLLEHLGCLYKFHDRPVTYLYNTLHYYEHKLRDRPDLKRKLVSAIIGS 1028

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665 1040 FKDIKPANWAVTDAYLNYMKRPVED-LAWNPElDYYFKLISRVVDTFQGKSP--FPHVDWRFNEFANAGVHALHITCIEL 1116
Cdd:pfam11573 1029 LKDCRPPGWALTEAYEKYHQKSSDEqLIWLPE-DYYMKLIDRMVDTMDGKTPppFPAKDWRFNEFPNPGAHALYVTCVEL 1107

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665 1117 MALPVAANVVANNLIDLVVVGHKYIPRNTIEFWNNAIGVVLTALPEAYWSVINDRIISMMESPLLTYSPHP-EPFQMMNF 1195
Cdd:pfam11573 1108 MALPVSPETVANALIDVVQKGYHLIPRNQIHLWINAIGLILTALPESYWSVLHDRIVEVLSNPELTNWTYPcSPFELFNF 1187

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665 1196 SDSHKSMSEMQPSYLIALIHSFFHHASIGQITPIPQFLRERVKPIIKTEEQFLFIVHIVCPFLQRLYAERTRRAMEVTIE 1275
Cdd:pfam11573 1188 DNYHESLLENRASYILALAHAVWHHAGIGQLNPFPQFVKEKLLPHVKTEEQLLYLCHLVGPFLQRFRAERERGVLDITKL 1267

                         1290      1300      1310
                   ....*....|....*....|....*....|....
gi 1005957665 1276 LYSFLEVIDKNCTELRFMDTITDLLYHMKYHITG 1309
Cdd:pfam11573 1268 LYELLEQVDKEGVELRYMDPICDLLYHIKYMFVG 1301
 
Name Accession Description Interval E-value
Med23 pfam11573
Mediator complex subunit 23; Med23 is one of the subunits of the Tail portion of the Mediator ...
 10-1309 0e+00

Mediator complex subunit 23; Med23 is one of the subunits of the Tail portion of the Mediator complex that regulates RNA polymerase II activity. Med23 is required for heat-shock-specific gene expression, and has been shown to mediate transcriptional activation of E1A in mice.


Pssm-ID: 463299  Cd Length: 1301  Bit Score: 1996.47  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665   10 TVSDVHNFIDSILRTEELEAIFTGYIVESSVNEECKIKNYEEQMTALIKSCdTPEKIELMLRDYLNGAGSIPNVNKVRLL 89
Cdd:pfam11573    1 EVNQVKSIINEILKVEIIEEAFSGFTSNLPDDEKEKTAILRKQFNNMMSKM-SEEEKESLVKELIKLVHHVAEKNRLDFL 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665   90 LSMLEHAINNHLLSAKSVCEAILNCEHLHINKQIFFCQSFELIHRVISQVDYKGVRDIIRFMIEKIHTIPIEANIAMLPQ 169
Cdd:pfam11573   80 FQLLEYAVQKGIISARLVCEGLIMSEKLVLCNRLFWQECFKLIRKIIPGVDYKGVREILKYCLEKARRLPYSLSPEKVPQ 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  170 LDVMRKVLDYALNRNSSLLPAYLAFDEIKKK---SDKWMHWKFADLFSAFVESFRPVAQMVSIINRSKLLPIV---GYSS 243
Cdd:pfam11573  160 LRALENVILYILDRNACLLPAYFIVNEIMKGypdAKMWPHWRLAELLSNFVESFRPIAQMVSIIGRSFMLPVVehsGYAD 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  244 TLNQSWQLNAATAAFDLKGLLPYNNELTRPQIGLLRYVLEQPYSREMIYFMLSLTNKAKSRCPILEEQLVALIVLAMEKS 323
Cdd:pfam11573  240 HLTSPWKLDPATLKFQLKGNLPYRPELLEPQTYLLRYVLEQPYSRDMVCSMLGLQKQHKQRCKALEEQLVELMICAMERS 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  324 ENEtnnqeDTDYSQTQCLWQILSGHLITFIILNHISFPQLVRSLHESLAARNSKKGRDHLMWMLLQYISGSIQKTPLTDF 403
Cdd:pfam11573  320 ETE-----PEDEPITHWLWLHLSSQLIYFVLFQFASFPNIVKSLHEKLAGRDLTRGRDHLMWVLLQFISGSIQKNPLSDF 394

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  404 LPFFKLHDLLYPEKDPLPVPDITKPICTHTFAISSIWIHLLKKAENEPQKMIRPIPNCLRLHVEFLHQTFMSSDLP-ASL 482
Cdd:pfam11573  395 LPILKLYDLLYPEKEPLPVPDYNKPLCTHQMAATCIWIHLLKKAQDENQKLQRPIPDTLKSHHEFLQHLVLNNDSPnLAM 474

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  483 TVDSKIPLICNAYSTNSDYYNRILTILCDTIKCNSRSGSTGGNTNGAIIPLSVSLLDSVTLHTKMSLISNIVAQINKSSS 562
Cdd:pfam11573  475 GSDYRIALLCNAYSTNTEYFSRPMPALVETILGNSKSRSPGCNAPGPTTPLSMEFLDSLTVHSKMSLIHSIVTHVIKFAQ 554

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  563 KDGTI-ISPALAETYSRLLIYIELETLGIKNFIQQVIPNAIRTQSWGTLNILFEMFIHRLHHIPAPYRVQFLNQLHYLAN 641
Cdd:pfam11573  555 SKSSVaLAPALVETYSRLLVYTEIESLGIKGFISQLLPTVFKSQAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAN 634

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  642 SPHSNQIQLHSCMESTALKLITGFTSEQVLliTQLNRYQNEPKI-RISHDSEELNKVLILTLARAIHVTGCDTLIE-WCK 719
Cdd:pfam11573  635 VPQTNQTQLHLCVESTALRLITGLGSSEVQ--PQLSRFLNEPKTfLVSQESEELNRALILTLARAIHITGTGTDSEsWCK 712

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  720 ELLSNIMNSTPLAWSSCTLKCFPPAITEYYQNFNTVTENKAQLKQSVEEEYRKWITMSNENDIIAHFSIQGTPPLFLCLL 799
Cdd:pfam11573  713 ELLETIMQNTPHGWPQHTLSCFPPWLLEFFKQNNVPKENKQQLKKNVEEEYRKWTSMTNENDIIAHFSVPGTPPLFLCLL 792

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  800 WKMILENDRINPIAYKILDRIGAKALSSHLRILVDYLVNEFTNLCGTQNVTKYIDKLNDLIWKSHVITLDRLLLCLTLRA 879
Cdd:pfam11573  793 WKMLLETDRITPIAYKVLERIGARALSAHLRKFCDYLVFEFTNSCGGQHVNKCADALNDMIWKYNIVTIDRLVLCLALRP 872

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  880 YEGNEAQVSLFIIQMLLLKTTDFSNRVADFVREMSPEHWKQSNWHEKHHALHRKYPEKFYFEGLADISgqNMQHSYLPTY 959
Cdd:pfam11573  873 QEGNEAQVCFFIIQLLLLKTTEFRNRVQDFVKENSPEHWKQPNWHEKHLAYHRKFPEKFAPEGVAEYD--SSSNPYLPTY 950

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665  960 FSNICLRFIPVLDLIIHRYLELPPGSPSplIDSLLEKYGCLYKFHDRPLTYLYETLHYYEHKMRERPALRRKLVSIIIGA 1039
Cdd:pfam11573  951 FGNVCLRFLPVLDIVIHRALELPPVSKS--LETLLEHLGCLYKFHDRPVTYLYNTLHYYEHKLRDRPDLKRKLVSAIIGS 1028

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665 1040 FKDIKPANWAVTDAYLNYMKRPVED-LAWNPElDYYFKLISRVVDTFQGKSP--FPHVDWRFNEFANAGVHALHITCIEL 1116
Cdd:pfam11573 1029 LKDCRPPGWALTEAYEKYHQKSSDEqLIWLPE-DYYMKLIDRMVDTMDGKTPppFPAKDWRFNEFPNPGAHALYVTCVEL 1107

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665 1117 MALPVAANVVANNLIDLVVVGHKYIPRNTIEFWNNAIGVVLTALPEAYWSVINDRIISMMESPLLTYSPHP-EPFQMMNF 1195
Cdd:pfam11573 1108 MALPVSPETVANALIDVVQKGYHLIPRNQIHLWINAIGLILTALPESYWSVLHDRIVEVLSNPELTNWTYPcSPFELFNF 1187

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1005957665 1196 SDSHKSMSEMQPSYLIALIHSFFHHASIGQITPIPQFLRERVKPIIKTEEQFLFIVHIVCPFLQRLYAERTRRAMEVTIE 1275
Cdd:pfam11573 1188 DNYHESLLENRASYILALAHAVWHHAGIGQLNPFPQFVKEKLLPHVKTEEQLLYLCHLVGPFLQRFRAERERGVLDITKL 1267

                         1290      1300      1310
                   ....*....|....*....|....*....|....
gi 1005957665 1276 LYSFLEVIDKNCTELRFMDTITDLLYHMKYHITG 1309
Cdd:pfam11573 1268 LYELLEQVDKEGVELRYMDPICDLLYHIKYMFVG 1301
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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