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Conserved domains on  [gi|167009131|sp|Q91X84|]
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RecName: Full=CREB-regulated transcription coactivator 3; AltName: Full=Transducer of regulated cAMP response element-binding protein 3; Short=TORC-3; Short=Transducer of CREB protein 3

Protein Classification

CREB-regulated transcription coactivator( domain architecture ID 10583816)

CREB-regulated transcription coactivator enhances the activity of CRE-depended transcription via a phosphorylation-independent interaction with the bZIP DNA binding/dimerization domain of CREB (cAMP Response Element-Binding)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TORC_M pfam12885
Transducer of regulated CREB activity middle domain; This family includes the region between ...
 159-321 5.03e-68

Transducer of regulated CREB activity middle domain; This family includes the region between the N and C terminus of TORC proteins. TORC (Transducer of regulated CREB activity) is a protein family of coactivators that enhances the activity of CRE-depended transcription via a phosphorylation-independent interaction with the bZIP DNA binding/dimerization domain of CREB (cAMP Response Element-Binding). Although the C- and N- terminal domains of these proteins have been well characterized, no functional role has been assigned to the central region, yet.


:

Pssm-ID: 463739  Cd Length: 154  Bit Score: 218.08  E-value: 5.03e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167009131  159 RTNSDSALHTSALSTKPQDPYGGGGQSAWPAPYmgfcdgendGHAEVAAFPGPLKEENLLNVPKPLPKHLWESKEIQSLS 238
Cdd:pfam12885   1 RTNSDSALHTSAMNPNPQDPFTGGSQELQPAPR---------GFGRVLLLTVPGTEENLLEVDKPLPKQLWDAKKVQSLS 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167009131  239 GRPRSCDVGGGNAFPHNGQNTGLSPFLGTLNTGGSLPDLTNLHYSAPLPASLDTSDHLFGSMSVGNSVGNLPAAMTHLGI 318
Cdd:pfam12885  72 SRPKSCEVPGINIFPSPDQNATLSLFPAALNTGGSLPDLTNLHFPSPLPTPLDPEDTAFPSLSGGNSTGNLAAAMTHLGI 151


                  ...
gi 167009131  319 RTS 321
Cdd:pfam12885 152 SSS 154
TORC_C pfam12886
Transducer of regulated CREB activity, C terminus; This family includes the C terminal region ...
 545-619 4.55e-31

Transducer of regulated CREB activity, C terminus; This family includes the C terminal region of TORC proteins. TORC (Transducer of regulated CREB activity) is a protein family of coactivators that enhances the activity of CRE-depended transcription via a phosphorylation-independent interaction with the bZIP DNA binding/dimerization domain of CREB (cAMP Response Element-Binding). The C terminus region is negatively charged, resembling the transcription activation domains. When this domain, from all three human TORC proteins, was expressed as fusion proteins with the DNA-binding domain of GAL4 (GAL4-BD), and tested for induction of a minimal promoter linked to GAL4-binding sites (UAS-GAL4), UAS-GAL4 was potently induced by GAL4-BD fusions containing the C-terminal portion of all three human TORCs.


:

Pssm-ID: 463740  Cd Length: 75  Bit Score: 115.57  E-value: 4.55e-31
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 167009131  545 PGTILTEDTNSNLFKGLSGGLSGMPEVSLDMDTPFPLEEELQIEPLSLDGLNMLSDSSMGLLDPSVEETFRADRL 619
Cdd:pfam12886   1 PNIILTGDSSPGFSKDLSSALAGVPEVSFDADDLFPLDDELGIEPLDLDGLQMLSDPDMVLPDPATEDTFRSDRL 75
TORC_N pfam12884
Transducer of regulated CREB activity, N terminus; This family includes the N terminal region ...
 11-64 1.86e-18

Transducer of regulated CREB activity, N terminus; This family includes the N terminal region of TORC proteins. TORC (Transducer of regulated CREB activity) is a protein family of coactivators that enhances the activity of CRE-depended transcription via a phosphorylation-independent interaction with the bZIP DNA binding/dimerization domain of CREB (cAMP Response Element-Binding). The proteins display a highly conserved predicted N-terminal coiled-coil domain and an invariant sequence matching a protein kinase A (PKA) phosphorylation consensus sequence (RKXS). The coiled-coil structure interacts with the bZIP domain of CREB. This interaction may occur via ionic bonds because it is disrupted under high-salt conditions. In addition to CREB-binding, the N-terminal region plays a role in the tetramer formation of TORCs, but the physiological function of the multimeric complex has not been clarified yet.


:

Pssm-ID: 463738  Cd Length: 63  Bit Score: 79.42  E-value: 1.86e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 167009131   11 NPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRV-----QFQKLQQLRLT----QYHGGSLP 64
Cdd:pfam12884   1 NPRKFSEKIALHKQKQAEETAAFERIMREVSATTRdptqsSNQKQQQLRLGllgpQYRGGSLP 63
PRK10263 super family cl35903
DNA translocase FtsK; Provisional
 387-533 3.89e-05

DNA translocase FtsK; Provisional


The actual alignment was detected with superfamily member PRK10263:

Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 47.00  E-value: 3.89e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167009131  387 QPPVSPLTLSPGPEAHQGFSRQLSATSPLNPYPASQMVTSEQSPLSFLPTDAQAQvsppppyptPQELPQPLLQQPH--- 463
Cdd:PRK10263  754 QPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQ---------QPVAPQPQYQQPQqpv 824

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 167009131  464 AQEPPTQQPQAAPS-LPQSDF--QLLTAQGsaltsffpDVRFDQQPMRPSPAFPQQVPlvQQSHREPQDSFHL 533
Cdd:PRK10263  825 APQPQYQQPQQPVApQPQDTLlhPLLMRNG--------DSRPLHKPTTPLPSLDLLTP--PPSEVEPVDTFAL 887
 
Name Accession Description Interval E-value
TORC_M pfam12885
Transducer of regulated CREB activity middle domain; This family includes the region between ...
 159-321 5.03e-68

Transducer of regulated CREB activity middle domain; This family includes the region between the N and C terminus of TORC proteins. TORC (Transducer of regulated CREB activity) is a protein family of coactivators that enhances the activity of CRE-depended transcription via a phosphorylation-independent interaction with the bZIP DNA binding/dimerization domain of CREB (cAMP Response Element-Binding). Although the C- and N- terminal domains of these proteins have been well characterized, no functional role has been assigned to the central region, yet.


Pssm-ID: 463739  Cd Length: 154  Bit Score: 218.08  E-value: 5.03e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167009131  159 RTNSDSALHTSALSTKPQDPYGGGGQSAWPAPYmgfcdgendGHAEVAAFPGPLKEENLLNVPKPLPKHLWESKEIQSLS 238
Cdd:pfam12885   1 RTNSDSALHTSAMNPNPQDPFTGGSQELQPAPR---------GFGRVLLLTVPGTEENLLEVDKPLPKQLWDAKKVQSLS 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167009131  239 GRPRSCDVGGGNAFPHNGQNTGLSPFLGTLNTGGSLPDLTNLHYSAPLPASLDTSDHLFGSMSVGNSVGNLPAAMTHLGI 318
Cdd:pfam12885  72 SRPKSCEVPGINIFPSPDQNATLSLFPAALNTGGSLPDLTNLHFPSPLPTPLDPEDTAFPSLSGGNSTGNLAAAMTHLGI 151


                  ...
gi 167009131  319 RTS 321
Cdd:pfam12885 152 SSS 154
TORC_C pfam12886
Transducer of regulated CREB activity, C terminus; This family includes the C terminal region ...
 545-619 4.55e-31

Transducer of regulated CREB activity, C terminus; This family includes the C terminal region of TORC proteins. TORC (Transducer of regulated CREB activity) is a protein family of coactivators that enhances the activity of CRE-depended transcription via a phosphorylation-independent interaction with the bZIP DNA binding/dimerization domain of CREB (cAMP Response Element-Binding). The C terminus region is negatively charged, resembling the transcription activation domains. When this domain, from all three human TORC proteins, was expressed as fusion proteins with the DNA-binding domain of GAL4 (GAL4-BD), and tested for induction of a minimal promoter linked to GAL4-binding sites (UAS-GAL4), UAS-GAL4 was potently induced by GAL4-BD fusions containing the C-terminal portion of all three human TORCs.


Pssm-ID: 463740  Cd Length: 75  Bit Score: 115.57  E-value: 4.55e-31
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 167009131  545 PGTILTEDTNSNLFKGLSGGLSGMPEVSLDMDTPFPLEEELQIEPLSLDGLNMLSDSSMGLLDPSVEETFRADRL 619
Cdd:pfam12886   1 PNIILTGDSSPGFSKDLSSALAGVPEVSFDADDLFPLDDELGIEPLDLDGLQMLSDPDMVLPDPATEDTFRSDRL 75
TORC_N pfam12884
Transducer of regulated CREB activity, N terminus; This family includes the N terminal region ...
 11-64 1.86e-18

Transducer of regulated CREB activity, N terminus; This family includes the N terminal region of TORC proteins. TORC (Transducer of regulated CREB activity) is a protein family of coactivators that enhances the activity of CRE-depended transcription via a phosphorylation-independent interaction with the bZIP DNA binding/dimerization domain of CREB (cAMP Response Element-Binding). The proteins display a highly conserved predicted N-terminal coiled-coil domain and an invariant sequence matching a protein kinase A (PKA) phosphorylation consensus sequence (RKXS). The coiled-coil structure interacts with the bZIP domain of CREB. This interaction may occur via ionic bonds because it is disrupted under high-salt conditions. In addition to CREB-binding, the N-terminal region plays a role in the tetramer formation of TORCs, but the physiological function of the multimeric complex has not been clarified yet.


Pssm-ID: 463738  Cd Length: 63  Bit Score: 79.42  E-value: 1.86e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 167009131   11 NPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRV-----QFQKLQQLRLT----QYHGGSLP 64
Cdd:pfam12884   1 NPRKFSEKIALHKQKQAEETAAFERIMREVSATTRdptqsSNQKQQQLRLGllgpQYRGGSLP 63
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 387-533 3.89e-05

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 47.00  E-value: 3.89e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167009131  387 QPPVSPLTLSPGPEAHQGFSRQLSATSPLNPYPASQMVTSEQSPLSFLPTDAQAQvsppppyptPQELPQPLLQQPH--- 463
Cdd:PRK10263  754 QPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQ---------QPVAPQPQYQQPQqpv 824

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 167009131  464 AQEPPTQQPQAAPS-LPQSDF--QLLTAQGsaltsffpDVRFDQQPMRPSPAFPQQVPlvQQSHREPQDSFHL 533
Cdd:PRK10263  825 APQPQYQQPQQPVApQPQDTLlhPLLMRNG--------DSRPLHKPTTPLPSLDLLTP--PPSEVEPVDTFAL 887
 
Name Accession Description Interval E-value
TORC_M pfam12885
Transducer of regulated CREB activity middle domain; This family includes the region between ...
 159-321 5.03e-68

Transducer of regulated CREB activity middle domain; This family includes the region between the N and C terminus of TORC proteins. TORC (Transducer of regulated CREB activity) is a protein family of coactivators that enhances the activity of CRE-depended transcription via a phosphorylation-independent interaction with the bZIP DNA binding/dimerization domain of CREB (cAMP Response Element-Binding). Although the C- and N- terminal domains of these proteins have been well characterized, no functional role has been assigned to the central region, yet.


Pssm-ID: 463739  Cd Length: 154  Bit Score: 218.08  E-value: 5.03e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167009131  159 RTNSDSALHTSALSTKPQDPYGGGGQSAWPAPYmgfcdgendGHAEVAAFPGPLKEENLLNVPKPLPKHLWESKEIQSLS 238
Cdd:pfam12885   1 RTNSDSALHTSAMNPNPQDPFTGGSQELQPAPR---------GFGRVLLLTVPGTEENLLEVDKPLPKQLWDAKKVQSLS 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167009131  239 GRPRSCDVGGGNAFPHNGQNTGLSPFLGTLNTGGSLPDLTNLHYSAPLPASLDTSDHLFGSMSVGNSVGNLPAAMTHLGI 318
Cdd:pfam12885  72 SRPKSCEVPGINIFPSPDQNATLSLFPAALNTGGSLPDLTNLHFPSPLPTPLDPEDTAFPSLSGGNSTGNLAAAMTHLGI 151


                  ...
gi 167009131  319 RTS 321
Cdd:pfam12885 152 SSS 154
TORC_C pfam12886
Transducer of regulated CREB activity, C terminus; This family includes the C terminal region ...
 545-619 4.55e-31

Transducer of regulated CREB activity, C terminus; This family includes the C terminal region of TORC proteins. TORC (Transducer of regulated CREB activity) is a protein family of coactivators that enhances the activity of CRE-depended transcription via a phosphorylation-independent interaction with the bZIP DNA binding/dimerization domain of CREB (cAMP Response Element-Binding). The C terminus region is negatively charged, resembling the transcription activation domains. When this domain, from all three human TORC proteins, was expressed as fusion proteins with the DNA-binding domain of GAL4 (GAL4-BD), and tested for induction of a minimal promoter linked to GAL4-binding sites (UAS-GAL4), UAS-GAL4 was potently induced by GAL4-BD fusions containing the C-terminal portion of all three human TORCs.


Pssm-ID: 463740  Cd Length: 75  Bit Score: 115.57  E-value: 4.55e-31
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 167009131  545 PGTILTEDTNSNLFKGLSGGLSGMPEVSLDMDTPFPLEEELQIEPLSLDGLNMLSDSSMGLLDPSVEETFRADRL 619
Cdd:pfam12886   1 PNIILTGDSSPGFSKDLSSALAGVPEVSFDADDLFPLDDELGIEPLDLDGLQMLSDPDMVLPDPATEDTFRSDRL 75
TORC_N pfam12884
Transducer of regulated CREB activity, N terminus; This family includes the N terminal region ...
 11-64 1.86e-18

Transducer of regulated CREB activity, N terminus; This family includes the N terminal region of TORC proteins. TORC (Transducer of regulated CREB activity) is a protein family of coactivators that enhances the activity of CRE-depended transcription via a phosphorylation-independent interaction with the bZIP DNA binding/dimerization domain of CREB (cAMP Response Element-Binding). The proteins display a highly conserved predicted N-terminal coiled-coil domain and an invariant sequence matching a protein kinase A (PKA) phosphorylation consensus sequence (RKXS). The coiled-coil structure interacts with the bZIP domain of CREB. This interaction may occur via ionic bonds because it is disrupted under high-salt conditions. In addition to CREB-binding, the N-terminal region plays a role in the tetramer formation of TORCs, but the physiological function of the multimeric complex has not been clarified yet.


Pssm-ID: 463738  Cd Length: 63  Bit Score: 79.42  E-value: 1.86e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 167009131   11 NPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRV-----QFQKLQQLRLT----QYHGGSLP 64
Cdd:pfam12884   1 NPRKFSEKIALHKQKQAEETAAFERIMREVSATTRdptqsSNQKQQQLRLGllgpQYRGGSLP 63
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 387-533 3.89e-05

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 47.00  E-value: 3.89e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167009131  387 QPPVSPLTLSPGPEAHQGFSRQLSATSPLNPYPASQMVTSEQSPLSFLPTDAQAQvsppppyptPQELPQPLLQQPH--- 463
Cdd:PRK10263  754 QPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQ---------QPVAPQPQYQQPQqpv 824

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 167009131  464 AQEPPTQQPQAAPS-LPQSDF--QLLTAQGsaltsffpDVRFDQQPMRPSPAFPQQVPlvQQSHREPQDSFHL 533
Cdd:PRK10263  825 APQPQYQQPQQPVApQPQDTLlhPLLMRNG--------DSRPLHKPTTPLPSLDLLTP--PPSEVEPVDTFAL 887
PHA03378 PHA03378
EBNA-3B; Provisional
 310-543 5.26e-04

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 43.13  E-value: 5.26e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167009131 310 PAAMTHLGIRTSSglqssrSNPSIQATLSKMALSSSLKCHPQPSVANASA-LHPSLRLFSLSNPSLSTTNLS---GPSRR 385
Cdd:PHA03378 640 PITFNVLVFPTPH------QPPQVEITPYKPTWTQIGHIPYQPSPTGANTmLPIQWAPGTMQPPPRAPTPMRppaAPPGR 713

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167009131 386 RQPPVSPLTLSPGPEAHQGFSRQLSATSPLNPYPASQMVTSEQSPLSFLPTDAQAQVSPPPPYPTPQELPQPLLQQPHAQ 465
Cdd:PHA03378 714 AQRPAAATGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGAPTPQPPPQAPPAPQQRPRGA 793

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 167009131 466 EPPTQQPQAAPSLPQ-SDFQLLTAQGSALTSFFPDVRFDQQPMRPSPAFPqqvplvqqSHREPQDSFHLRPNPYSSCGS 543
Cdd:PHA03378 794 PTPQPPPQAGPTSMQlMPRAAPGQQGPTKQILRQLLTGGVKRGRPSLKKP--------AALERQAAAGPTPSPGSGTSD 864
PHA03247 PHA03247
large tegument protein UL36; Provisional
 332-540 3.00e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.08  E-value: 3.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167009131  332 SIQATLSKMALSSSLKCHPQPSVANASALHPSLRLFSLSNPSLSTTNLSgPSRRRQPPVSPLTL----SPG-PEAHQGFS 406
Cdd:PHA03247 2790 SLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTA-PPPPPGPPPPSLPLggsvAPGgDVRRRPPS 2868

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167009131  407 RQLSATSPLNPYPASQMVTSEQSPLsflPTDAQAQVSPPPPYPTPQELPQPLLQQPHAQEPPtqQPQAAPSLP-QSDFQL 485
Cdd:PHA03247 2869 RSPAAKPAAPARPPVRRLARPAVSR---STESFALPPDQPERPPQPQAPPPPQPQPQPPPPP--QPQPPPPPPpRPQPPL 2943

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 167009131  486 LTAQGSALTSffpdvrfDQQPMRPSPAF----PQQVPLVQQSHREPQDSfhlRPNPYSS 540
Cdd:PHA03247 2944 APTTDPAGAG-------EPSGAVPQPWLgalvPGRVAVPRFRVPQPAPS---REAPASS 2992
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 351-528 7.72e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 39.68  E-value: 7.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167009131  351 QPSVANASALHPSLRLFSLSNPSLSTTNLSGPSRRRQPPVSPLTLSPGPE--------AHQGFSRQLSATSPLNPY--PA 420
Cdd:PRK10263  318 EPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQtgepviapAPEGYPQQSQYAQPAVQYnePL 397

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167009131  421 SQMVTSEQSPLSFLPTD--AQAQVSPPPPYPTPQELPQPLLQQPHAQEPPTQQPQAAPSLPQSDFQLLTAQgsaltsffp 498
Cdd:PRK10263  398 QQPVQPQQPYYAPAAEQpaQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTY--------- 468

                         170       180       190
                  ....*....|....*....|....*....|
gi 167009131  499 dvrfdQQPMRPSPAFPQQVPLVQQSHREPQ 528
Cdd:PRK10263  469 -----QQPAAQEPLYQQPQPVEQQPVVEPE 493
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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