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Conserved domains on  [gi|1212621738|ref|NP_001340026|]
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phosphoribosyl pyrophosphate synthase-associated protein 2 isoform 5 [Homo sapiens]

Protein Classification

phosphoribosyl pyrophosphate synthase-associated protein( domain architecture ID 11226557)

phosphoribosyl pyrophosphate synthase-associated protein seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Pribosyl_synth pfam14572
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes ...
 134-318 5.24e-111

Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes from class EC:2.7.6.1, phosphoribosyl-pyrophosphate transferase.


:

Pssm-ID: 434046  Cd Length: 184  Bit Score: 319.84  E-value: 5.24e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 134 DYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGEAQDAESDLVDGRHSPPMVRSvAAIHPSLEIPMLIPKEKPPITVVG 213
Cdd:pfam14572   1 DYRNAVIVARSPGSAKRATSFAERLRLGIAVIHGEQKEAESDEVDGRQSPPPYRS-RTVSRSLGLPEIIPKEKPPMTVVG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 214 DVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFVMATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKLQCPKIKT 293
Cdd:pfam14572  80 DVGGRIAIIVDDMIDDVDSFVAAAELLKERGAYKIYVMATHGLLSSDAPRLLEASPIDEVVVTNTIPHEIQKMQCHKIKT 159

                         170       180
                  ....*....|....*....|....*
gi 1212621738 294 VDISMILSEAIRRIHNGESMSYLFR 318
Cdd:pfam14572 160 IDISQLIAEAIRRIHNGESMSYLFR 184
Pribosyltran_N pfam13793
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ...
 1-93 6.52e-43

N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.


:

Pssm-ID: 433483 [Multi-domain]  Cd Length: 117  Bit Score: 143.71  E-value: 6.52e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738   1 MGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKM-RKRGS 79
Cdd:pfam13793  24 LGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRASAKRITAVIPYFGYARQDRKdKPREP 103

                          90
                  ....*....|....
gi 1212621738  80 IVSKLLASMMCKAG 93
Cdd:pfam13793 104 ITAKLVADLLEAAG 117
 
Name Accession Description Interval E-value
Pribosyl_synth pfam14572
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes ...
 134-318 5.24e-111

Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes from class EC:2.7.6.1, phosphoribosyl-pyrophosphate transferase.


Pssm-ID: 434046  Cd Length: 184  Bit Score: 319.84  E-value: 5.24e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 134 DYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGEAQDAESDLVDGRHSPPMVRSvAAIHPSLEIPMLIPKEKPPITVVG 213
Cdd:pfam14572   1 DYRNAVIVARSPGSAKRATSFAERLRLGIAVIHGEQKEAESDEVDGRQSPPPYRS-RTVSRSLGLPEIIPKEKPPMTVVG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 214 DVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFVMATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKLQCPKIKT 293
Cdd:pfam14572  80 DVGGRIAIIVDDMIDDVDSFVAAAELLKERGAYKIYVMATHGLLSSDAPRLLEASPIDEVVVTNTIPHEIQKMQCHKIKT 159

                         170       180
                  ....*....|....*....|....*
gi 1212621738 294 VDISMILSEAIRRIHNGESMSYLFR 318
Cdd:pfam14572 160 IDISQLIAEAIRRIHNGESMSYLFR 184
PrsA COG0462
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ...
 1-318 4.39e-96

Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis


Pssm-ID: 440230 [Multi-domain]  Cd Length: 311  Bit Score: 286.57  E-value: 4.39e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738   1 MGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQ-CKMRKRGS 79
Cdd:COG0462    27 LGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRASARRITAVIPYYGYARQdRKFRPREP 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  80 IVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEipDYRNAVIVakSP--ASAKRAQSFAER 157
Cdd:COG0462   107 ITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSK--DLEDLVVV--SPdvGGVKRARAFAKR 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 158 LRLGIAVIHGEaqdaesdlvdgRHSPpmvRSVAAIHPSLEIpmlipKEKPPItVVGDV---GGriaiivddiiddvdSFL 234
Cdd:COG0462   183 LGAPLAIIDKR-----------RPGA---NEVEVMNIIGDV-----EGKTCI-IVDDMidtGG--------------TLV 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 235 AAAETLKERGAYKIFVMATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKlQCPKIKTVDISMILSEAIRRIHNGESMS 314
Cdd:COG0462   229 EAAEALKEAGAKSVYAAATHGVLSGPAVERLENSPIDELVVTDTIPLPEEK-RCDKIKVLSVAPLLAEAIRRIHEGESVS 307


                  ....
gi 1212621738 315 YLFR 318
Cdd:COG0462   308 SLFD 311
PRK01259 PRK01259
ribose-phosphate diphosphokinase;
13-318 5.24e-87

ribose-phosphate diphosphokinase;


Pssm-ID: 234929 [Multi-domain]  Cd Length: 309  Bit Score: 263.52  E-value: 5.24e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  13 ETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQ-CKMRKRGSIVSKLLASMMCK 91
Cdd:PRK01259   36 EISVEINENVRGKDVFIIQSTCAPTNDNLMELLIMIDALKRASAGRITAVIPYFGYARQdRKARSRVPITAKLVANLLET 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  92 AGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEipDYRNAVIVakSP--ASAKRAQSFAERLRLGIAVIhgea 169
Cdd:PRK01259  116 AGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQK--NLENLVVV--SPdvGGVVRARALAKRLDADLAII---- 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 170 qdaesdlvDGRHSPPMVRSVaaihpsleipmlipkekppITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIF 249
Cdd:PRK01259  188 --------DKRRPRANVSEV-------------------MNIIGDVEGRDCILVDDMIDTAGTLCKAAEALKERGAKSVY 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1212621738 250 VMATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKLQCPKIKTVDISMILSEAIRRIHNGESMSYLFR 318
Cdd:PRK01259  241 AYATHPVLSGGAIERIENSVIDELVVTDSIPLSEEAKKCDKIRVLSVAPLLAEAIRRISNEESVSSLFD 309
ribP_PPkin TIGR01251
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ...
 1-318 1.57e-84

ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]


Pssm-ID: 273523 [Multi-domain]  Cd Length: 308  Bit Score: 257.21  E-value: 1.57e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738   1 MGKVQVYQEPNRETRVQIQESVRGKDVFII-QTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMRKRG- 78
Cdd:TIGR01251  24 LGDVEVKRFPDGELYVRINESVRGKDVFIIqQSTSAPVNDNLMELLIMIDALKRASAKSITAVIPYYGYARQDKKFKSRe 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  79 SIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDyrNAVIVAKSPASAKRAQSFAERL 158
Cdd:TIGR01251 104 PISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKKILD--NPVVVSPDAGGVERAKKVADAL 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 159 RLGIAVIHGEaqdaesdlvdgRHSPPMVRSVAAIhpsleipmlipkekppitvVGDVGGRIAIIVDDIIDDVDSFLAAAE 238
Cdd:TIGR01251 182 GCPLAIIDKR-----------RISATNEVEVMNL-------------------VGDVEGKDVVIVDDIIDTGGTIAKAAE 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 239 TLKERGAYKIFVMATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVqklQCPKIKTVDISMILSEAIRRIHNGESMSYLFR 318
Cdd:TIGR01251 232 ILKSAGAKRVIAAATHGVFSGPAIERIANAGVEEVIVTNTIPHEK---HKPKVSVISVAPLIAEAIRRIHNNESVSSLFD 308
Pribosyltran_N pfam13793
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ...
 1-93 6.52e-43

N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.


Pssm-ID: 433483 [Multi-domain]  Cd Length: 117  Bit Score: 143.71  E-value: 6.52e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738   1 MGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKM-RKRGS 79
Cdd:pfam13793  24 LGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRASAKRITAVIPYFGYARQDRKdKPREP 103

                          90
                  ....*....|....
gi 1212621738  80 IVSKLLASMMCKAG 93
Cdd:pfam13793 104 ITAKLVADLLEAAG 117
PLN02297 PLN02297
ribose-phosphate pyrophosphokinase
 20-154 8.99e-04

ribose-phosphate pyrophosphokinase


Pssm-ID: 177934 [Multi-domain]  Cd Length: 326  Bit Score: 40.44  E-value: 8.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  20 ESVRGKDVFIIQTVSKdvNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMRKRGSIVSKL-LASM-----MCKAG 93
Cdd:PLN02297   62 HGIRGQHVAFLASFSS--PAVIFEQLSVIYALPKLFVASFTLVLPFFPTGTSERVEREGDVATAFtLARIlsnipISRGG 139

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1212621738  94 LTHLITMDLHQKEIQGFFNipvDNLRAS-----PFLLQYIQeEIPDYRNAVIVAKSPASAKRAQSF 154
Cdd:PLN02297  140 PTSLVIFDIHALQERFYFG---DNVLPCfesgiPLLKKRLQ-QLPDSDNIVIAFPDDGAWKRFHKQ 201
 
Name Accession Description Interval E-value
Pribosyl_synth pfam14572
Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes ...
 134-318 5.24e-111

Phosphoribosyl synthetase-associated domain; This family includes several examples of enzymes from class EC:2.7.6.1, phosphoribosyl-pyrophosphate transferase.


Pssm-ID: 434046  Cd Length: 184  Bit Score: 319.84  E-value: 5.24e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 134 DYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGEAQDAESDLVDGRHSPPMVRSvAAIHPSLEIPMLIPKEKPPITVVG 213
Cdd:pfam14572   1 DYRNAVIVARSPGSAKRATSFAERLRLGIAVIHGEQKEAESDEVDGRQSPPPYRS-RTVSRSLGLPEIIPKEKPPMTVVG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 214 DVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFVMATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKLQCPKIKT 293
Cdd:pfam14572  80 DVGGRIAIIVDDMIDDVDSFVAAAELLKERGAYKIYVMATHGLLSSDAPRLLEASPIDEVVVTNTIPHEIQKMQCHKIKT 159

                         170       180
                  ....*....|....*....|....*
gi 1212621738 294 VDISMILSEAIRRIHNGESMSYLFR 318
Cdd:pfam14572 160 IDISQLIAEAIRRIHNGESMSYLFR 184
PrsA COG0462
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; ...
 1-318 4.39e-96

Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism]; Phosphoribosylpyrophosphate synthetase is part of the Pathway/BioSystem: Histidine biosynthesis, Purine biosynthesis


Pssm-ID: 440230 [Multi-domain]  Cd Length: 311  Bit Score: 286.57  E-value: 4.39e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738   1 MGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQ-CKMRKRGS 79
Cdd:COG0462    27 LGKAEVRRFSDGEIYVRIEESVRGRDVFVIQSTSPPVNDNLMELLIMIDALKRASARRITAVIPYYGYARQdRKFRPREP 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  80 IVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEipDYRNAVIVakSP--ASAKRAQSFAER 157
Cdd:COG0462   107 ITAKLVADLLEAAGADRVLTVDLHAPQIQGFFDIPVDHLYAAPLLADYIKSK--DLEDLVVV--SPdvGGVKRARAFAKR 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 158 LRLGIAVIHGEaqdaesdlvdgRHSPpmvRSVAAIHPSLEIpmlipKEKPPItVVGDV---GGriaiivddiiddvdSFL 234
Cdd:COG0462   183 LGAPLAIIDKR-----------RPGA---NEVEVMNIIGDV-----EGKTCI-IVDDMidtGG--------------TLV 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 235 AAAETLKERGAYKIFVMATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKlQCPKIKTVDISMILSEAIRRIHNGESMS 314
Cdd:COG0462   229 EAAEALKEAGAKSVYAAATHGVLSGPAVERLENSPIDELVVTDTIPLPEEK-RCDKIKVLSVAPLLAEAIRRIHEGESVS 307


                  ....
gi 1212621738 315 YLFR 318
Cdd:COG0462   308 SLFD 311
PRK01259 PRK01259
ribose-phosphate diphosphokinase;
13-318 5.24e-87

ribose-phosphate diphosphokinase;


Pssm-ID: 234929 [Multi-domain]  Cd Length: 309  Bit Score: 263.52  E-value: 5.24e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  13 ETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQ-CKMRKRGSIVSKLLASMMCK 91
Cdd:PRK01259   36 EISVEINENVRGKDVFIIQSTCAPTNDNLMELLIMIDALKRASAGRITAVIPYFGYARQdRKARSRVPITAKLVANLLET 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  92 AGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEipDYRNAVIVakSP--ASAKRAQSFAERLRLGIAVIhgea 169
Cdd:PRK01259  116 AGADRVLTMDLHADQIQGFFDIPVDNLYGSPILLEDIKQK--NLENLVVV--SPdvGGVVRARALAKRLDADLAII---- 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 170 qdaesdlvDGRHSPPMVRSVaaihpsleipmlipkekppITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIF 249
Cdd:PRK01259  188 --------DKRRPRANVSEV-------------------MNIIGDVEGRDCILVDDMIDTAGTLCKAAEALKERGAKSVY 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1212621738 250 VMATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKLQCPKIKTVDISMILSEAIRRIHNGESMSYLFR 318
Cdd:PRK01259  241 AYATHPVLSGGAIERIENSVIDELVVTDSIPLSEEAKKCDKIRVLSVAPLLAEAIRRISNEESVSSLFD 309
ribP_PPkin TIGR01251
ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In ...
 1-318 1.57e-84

ribose-phosphate pyrophosphokinase; Alternate name: phosphoribosylpyrophosphate synthetase In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]


Pssm-ID: 273523 [Multi-domain]  Cd Length: 308  Bit Score: 257.21  E-value: 1.57e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738   1 MGKVQVYQEPNRETRVQIQESVRGKDVFII-QTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMRKRG- 78
Cdd:TIGR01251  24 LGDVEVKRFPDGELYVRINESVRGKDVFIIqQSTSAPVNDNLMELLIMIDALKRASAKSITAVIPYYGYARQDKKFKSRe 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  79 SIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDyrNAVIVAKSPASAKRAQSFAERL 158
Cdd:TIGR01251 104 PISAKLVANLLETAGADRVLTVDLHSPQIQGFFDVPVDNLYASPVLAEYLKKKILD--NPVVVSPDAGGVERAKKVADAL 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 159 RLGIAVIHGEaqdaesdlvdgRHSPPMVRSVAAIhpsleipmlipkekppitvVGDVGGRIAIIVDDIIDDVDSFLAAAE 238
Cdd:TIGR01251 182 GCPLAIIDKR-----------RISATNEVEVMNL-------------------VGDVEGKDVVIVDDIIDTGGTIAKAAE 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 239 TLKERGAYKIFVMATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVqklQCPKIKTVDISMILSEAIRRIHNGESMSYLFR 318
Cdd:TIGR01251 232 ILKSAGAKRVIAAATHGVFSGPAIERIANAGVEEVIVTNTIPHEK---HKPKVSVISVAPLIAEAIRRIHNNESVSSLFD 308
PLN02369 PLN02369
ribose-phosphate pyrophosphokinase
 1-318 8.51e-65

ribose-phosphate pyrophosphokinase


Pssm-ID: 215209 [Multi-domain]  Cd Length: 302  Bit Score: 206.47  E-value: 8.51e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738   1 MGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQ-CKMRKRGS 79
Cdd:PLN02369   15 LGKITIKRFADGEIYVQLQESVRGCDVFLVQPTCPPANENLMELLIMIDACRRASAKRITAVIPYFGYARAdRKTQGRES 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  80 IVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDYRNAVIVAKSPASAKRAQSFAERLr 159
Cdd:PLN02369   95 IAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYGQPVILDYLASKTISSPDLVVVSPDVGGVARARAFAKKL- 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 160 lgiavihgeaQDAESDLVDGRHSPpmvrsvaaiHPSLEipmlipkekpPITVVGDVGGRIAIIVDDIIDDVDSFLAAAET 239
Cdd:PLN02369  174 ----------SDAPLAIVDKRRQG---------HNVAE----------VMNLIGDVKGKVAIMVDDMIDTAGTITKGAAL 224

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1212621738 240 LKERGAYKIFVMATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKlQCPKIKTVDISMILSEAIRRIHNGESMSYLFR 318
Cdd:PLN02369  225 LHQEGAREVYACATHAVFSPPAIERLSSGLFQEVIVTNTIPVSEKN-YFPQLTVLSVANLLGETIWRVHDDCSVSSIFD 302
PRK04923 PRK04923
ribose-phosphate diphosphokinase;
1-317 3.09e-64

ribose-phosphate diphosphokinase;


Pssm-ID: 179893 [Multi-domain]  Cd Length: 319  Bit Score: 205.55  E-value: 3.09e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738   1 MGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQ-CKMRK-RG 78
Cdd:PRK04923   30 MGKALVTRFSDGEVQVEIEESVRRQEVFVIQPTCAPSAENLMELLVLIDALKRASAASVTAVIPYFGYSRQdRRMRSsRV 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  79 SIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIpDYRNAVIVAKSPASAKRAQSFAERL 158
Cdd:PRK04923  110 PITAKVAAKMISAMGADRVLTVDLHADQIQGFFDVPVDNVYASPLLLADIWRAY-GTDNLIVVSPDVGGVVRARAVAKRL 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 159 rlgiavihgeaQDAESDLVDGRHSPPMVRSVaaihpsleipmlipkekppITVVGDVGGRIAIIVDDIIDDVDSFLAAAE 238
Cdd:PRK04923  189 -----------DDADLAIIDKRRPRANVATV-------------------MNIIGDVQGKTCVLVDDLVDTAGTLCAAAA 238

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1212621738 239 TLKERGAYKIFVMATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKLQCPKIKTVDISMILSEAIRRIHNGESMSYLF 317
Cdd:PRK04923  239 ALKQRGALKVVAYITHPVLSGPAVDNINNSQLDELVVTDTIPLSEAARACAKIRQLSVAELLAETIRRIAFGESVSSLY 317
PRK02269 PRK02269
ribose-phosphate diphosphokinase;
1-317 1.34e-63

ribose-phosphate diphosphokinase;


Pssm-ID: 167353 [Multi-domain]  Cd Length: 320  Bit Score: 203.87  E-value: 1.34e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738   1 MGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQ-CKMRKRGS 79
Cdd:PRK02269   29 LGKSSVRQFSDGEIQVNIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAESINVVMPYYGYARQdRKARSREP 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  80 IVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDYRNAVIVAKSPASAKRAQSFAERLR 159
Cdd:PRK02269  109 ITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRRGLVGDDVVVVSPDHGGVTRARKLAQFLK 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 160 LGIAVIhgeaqdaesdlvDGRHSppmvrsvaaihpslEIPMLIPKekpPITVVGDVGGRIAIIVDDIIDDVDSFLAAAET 239
Cdd:PRK02269  189 TPIAII------------DKRRS--------------VDKMNTSE---VMNIIGNVKGKKCILIDDMIDTAGTICHAADA 239

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1212621738 240 LKERGAYKIFVMATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKLqCPKIKTVDISMILSEAIRRIHNGESMSYLF 317
Cdd:PRK02269  240 LAEAGATEVYASCTHPVLSGPALDNIQKSAIEKLVVLDTIYLPEERL-IDKIEQISIADLLGEAIIRIHEKRPLSPLF 316
PRK03092 PRK03092
ribose-phosphate diphosphokinase;
11-317 8.69e-61

ribose-phosphate diphosphokinase;


Pssm-ID: 179535 [Multi-domain]  Cd Length: 304  Bit Score: 196.32  E-value: 8.69e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  11 NRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQ-CKMRKRGSIVSKLLASMM 89
Cdd:PRK03092   23 NGEIYVRFEESVRGCDAFVLQSHTAPINKWLMEQLIMIDALKRASAKRITVVLPFYPYARQdKKHRGREPISARLVADLF 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  90 CKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDyRNAVIVAKSPASAKRAQSFAERLrlgiavihGEA 169
Cdd:PRK03092  103 KTAGADRIMTVDLHTAQIQGFFDGPVDHLFAMPLLADYVRDKYDL-DNVTVVSPDAGRVRVAEQWADRL--------GGA 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 170 qdaesdlvdgrhspPMvrsvAAIHPSLEIpmLIPKEKPPITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIF 249
Cdd:PRK03092  174 --------------PL----AFIHKTRDP--TVPNQVVANRVVGDVEGRTCVLVDDMIDTGGTIAGAVRALKEAGAKDVI 233

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1212621738 250 VMATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKlQCPKIKTVDISMILSEAIRRIHNGESMSYLF 317
Cdd:PRK03092  234 IAATHGVLSGPAAERLKNCGAREVVVTDTLPIPEEK-RFDKLTVLSIAPLLARAIREVFEDGSVTSLF 300
PRK02812 PRK02812
ribose-phosphate pyrophosphokinase; Provisional
 13-318 2.64e-58

ribose-phosphate pyrophosphokinase; Provisional


Pssm-ID: 235072 [Multi-domain]  Cd Length: 330  Bit Score: 190.72  E-value: 2.64e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  13 ETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSK-QCKMRKRGSIVSKLLASMMCK 91
Cdd:PRK02812   57 ELYVQIQESIRGCDVYLIQPTCAPVNDHLMELLIMVDACRRASARQITAVIPYYGYARaDRKTAGRESITAKLVANLITK 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  92 AGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEipDYRNAVIVAKSPASAKRAQSFAERLRlgiavihgeaqD 171
Cdd:PRK02812  137 AGADRVLAMDLHSAQIQGYFDIPCDHVYGSPVLLDYLASK--NLEDIVVVSPDVGGVARARAFAKKLN-----------D 203

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 172 AESDLVDGRHSPPMVRSVaaihpsleipmlipkekppITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFVM 251
Cdd:PRK02812  204 APLAIIDKRRQAHNVAEV-------------------LNVIGDVKGKTAILVDDMIDTGGTICEGARLLRKEGAKQVYAC 264

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1212621738 252 ATHGLLSSDAPRRIEESAIDEVVVTNTIPHEvQKLQCPKIKTVDISMILSEAIRRIHNGESMSYLFR 318
Cdd:PRK02812  265 ATHAVFSPPAIERLSSGLFEEVIVTNTIPVP-EERRFPQLKVLSVANMLGEAIWRIHEESSVSSMFR 330
PRK02458 PRK02458
ribose-phosphate pyrophosphokinase; Provisional
 1-318 1.38e-57

ribose-phosphate pyrophosphokinase; Provisional


Pssm-ID: 235039 [Multi-domain]  Cd Length: 323  Bit Score: 188.41  E-value: 1.38e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738   1 MGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMRK-RGS 79
Cdd:PRK02458   33 LGKLSSRQFSDGEIMINIEESVRGDDIYIIQSTSFPVNDHLWELLIMIDACKRASANTVNVVLPYFGYARQDRIAKpREP 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  80 IVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDYRNAVIVAKSPASAKRAQSFAERLR 159
Cdd:PRK02458  113 ITAKLVANMLVKAGVDRVLTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCKKGLSGSDVVVVSPKNSGIKRARSLAEYLD 192

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 160 LGIAVIHGEAQDAESDlvDGrhsppmvrsvaaihpsleipmlipkekppiTVVGDVGGRIAIIVDDIIDDVDSFLAAAET 239
Cdd:PRK02458  193 APIAIIDYAQDDSERE--EG------------------------------YIIGDVAGKKAILIDDILNTGKTFAEAAKI 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 240 LKERGAYKIFVMATHGLLSSDAPRRIEESAIDEVVVTNTIpheVQKLQCPK-IKTVDISMILSEAIRRIHNGESMSYLFR 318
Cdd:PRK02458  241 VEREGATEIYAVASHGLFAGGAAEVLENAPIKEILVTDSV---ATKERVPKnVTYLSASELIADAIIRIHERKPLSPLFA 317
PTZ00145 PTZ00145
phosphoribosylpyrophosphate synthetase; Provisional
 1-317 5.23e-57

phosphoribosylpyrophosphate synthetase; Provisional


Pssm-ID: 240290 [Multi-domain]  Cd Length: 439  Bit Score: 190.47  E-value: 5.23e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738   1 MGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQ-CKMRKRGS 79
Cdd:PTZ00145  143 LGRVHLKRFADGEVSMQFLESIRGKDVYIIQPTCPPVNENLIELLLMISTCRRASAKKITAVIPYYGYARQdRKLSSRVP 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  80 IVSKLLASMMCKAGLTHLITMDLHQKEIQGFF--NIPVDNLRASPFLLQYIQEEipDYRNAVIVAKSPASAKRAQSFAER 157
Cdd:PTZ00145  223 ISAADVARMIEAMGVDRVVAIDLHSGQIQGFFgpRVPVDNLEAQLIGLDYFTKK--DLYKPVIVSPDAGGVYRARKFQDG 300

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 158 LrlgiavIHGEAQDAesdlvdgrhsppmvrsvaaihpslEIPMLI-----PKEKPPITVVGDVGGRIAIIVDDIIDDVDS 232
Cdd:PTZ00145  301 L------NHRGISDC------------------------GIAMLIkqrtkPNEIEKMDLVGNVYDSDVIIVDDMIDTSGT 350

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 233 FLAAAETLKERGAYKIFVMATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKLQCPKIKTVDISMILSEAIRRIHNGES 312
Cdd:PTZ00145  351 LCEAAKQLKKHGARRVFAFATHGLFSGPAIERIEASPLEEVVVTDTVKSNKNIDSCKKITKLSVSVLVADAIRRIHQKES 430


                  ....*
gi 1212621738 313 MSYLF 317
Cdd:PTZ00145  431 LNDLF 435
PRK00553 PRK00553
ribose-phosphate pyrophosphokinase; Provisional
 1-317 6.90e-52

ribose-phosphate pyrophosphokinase; Provisional


Pssm-ID: 179062 [Multi-domain]  Cd Length: 332  Bit Score: 173.95  E-value: 6.90e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738   1 MGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQ-CKMRKRGS 79
Cdd:PRK00553   33 PGEIVIQKFADGETYIRFDESVRNKDVVIFQSTCSPVNDSLMELLIAIDALKRGSAKSITAILPYYGYARQdRKTAGREP 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  80 IVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIpDYRNAVIVAKSPASAKRAQSFAERLR 159
Cdd:PRK00553  113 ITSKLVADLLTKAGVTRVTLTDIHSDQTQGFFDIPVDILRTYHVFLSRVLELL-GKKDLVVVSPDYGGVKRARLIAESLE 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 160 LGIAVIhgeaqdaesdlvDGRHSPPMVRSvaaihpsleipmlipkekpPITVVGDVGGRIAIIVDDIIDDVDSFLAAAET 239
Cdd:PRK00553  192 LPLAII------------DKRRPKHNVAE-------------------SINVLGEVKNKNCLIVDDMIDTGGTVIAAAKL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 240 LKERGAYKIFVMATHGLLSSDAPRRIEES----AIDEVVVTNTIPHEVQKlQCPKIKTVDISMILSEAIRRIHNGESMSY 315
Cdd:PRK00553  241 LKKQKAKKVCVMATHGLFNKNAIQLFDEAfkkkLIDKLFVSNSIPQTKFE-KKPQFKVVDLAHLYEEVLLCYANGGSISA 319


                  ..
gi 1212621738 316 LF 317
Cdd:PRK00553  320 IY 321
Pribosyltran_N pfam13793
N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found ...
 1-93 6.52e-43

N-terminal domain of ribose phosphate pyrophosphokinase; This family is frequently found N-terminal to the Pribosyltran, pfam00156.


Pssm-ID: 433483 [Multi-domain]  Cd Length: 117  Bit Score: 143.71  E-value: 6.52e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738   1 MGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKM-RKRGS 79
Cdd:pfam13793  24 LGKATVSRFSDGEIYVRIEESVRGKDVFIIQSTCPPVNDNLMELLIMIDALKRASAKRITAVIPYFGYARQDRKdKPREP 103

                          90
                  ....*....|....
gi 1212621738  80 IVSKLLASMMCKAG 93
Cdd:pfam13793 104 ITAKLVADLLEAAG 117
PRK00934 PRK00934
ribose-phosphate pyrophosphokinase; Provisional
 10-286 6.71e-34

ribose-phosphate pyrophosphokinase; Provisional


Pssm-ID: 234868 [Multi-domain]  Cd Length: 285  Bit Score: 125.80  E-value: 6.71e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  10 PNRETRVQIQESVRGKDVFIIQTVSKDvNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMRKRG-SIVSKLLASM 88
Cdd:PRK00934   32 PDGELYVRILGEIDGEDVVIISTTYPQ-DENLVELLLLIDALRDEGAKSITLVIPYLGYARQDKRFKPGePISARAIAKI 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  89 McKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEeipDYRNAVIVAKSPASAKRAQSFAERLrlGIAVIHGE 168
Cdd:PRK00934  111 I-SAYYDRIITINIHEPSILEFFPIPFINLDAAPLIAEYIGD---KLDDPLVLAPDKGALELAKEAAEIL--GCEYDYLE 184

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 169 AQdaesdlvdgRHSPPMVRsvaaIHPSlEIpmlipkekppitvvgDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKI 248
Cdd:PRK00934  185 KT---------RISPTEVE----IAPK-NL---------------DVKGKDVLIVDDIISTGGTMATAIKILKEQGAKKV 235

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1212621738 249 FVMATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKL 286
Cdd:PRK00934  236 YVACVHPVLVGDAILKLYNAGVDEIIVTDTLESEVSKI 273
PRK06827 PRK06827
phosphoribosylpyrophosphate synthetase; Provisional
 11-319 2.59e-27

phosphoribosylpyrophosphate synthetase; Provisional


Pssm-ID: 180714 [Multi-domain]  Cd Length: 382  Bit Score: 110.04  E-value: 2.59e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  11 NRETRVQIQESVRGKDVFIIQTVS--------------KDVNTTIMELLIMVYACKTScAKSIIGVIPYFPYSKQCKMRK 76
Cdd:PRK06827   64 NGEAKGEILESVRGKDIYILQDVGnysvtynmfgeknhMSPDDHFQDLKRTIDAIRGK-ARRITVIMPFLYESRQHKRKG 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  77 RGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNI-PVDNLRASPFLLQYIQEEIPDYR----NAVIVAKSPASAKRA 151
Cdd:PRK06827  143 RESLDCALALQELEELGVDNIITFDAHDPRIENAIPLmGFENLYPSYQIIKALLKNEKDLEidkdHLMVISPDTGAMDRA 222

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 152 QSFAERLRLGIAVIHGEaQDaESDLVDGRHsppmvrsvaaihpsleipmlipkekpPITVV----GDVGGRIAIIVDDII 227
Cdd:PRK06827  223 KYYASVLGVDLGLFYKR-RD-YSRVVNGRN--------------------------PIVAHeflgRDVEGKDVLIVDDMI 274

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 228 DDVDSFLAAAETLKERGAYKIFVMATHGLLsSDAPRRI----EESAIDEVVVTNTIPHEVQKLQCPKIKTVDISMILSEA 303
Cdd:PRK06827  275 ASGGSMIDAAKELKSRGAKKIIVAATFGFF-TNGLEKFdkayEEGYFDRIIGTNLVYHPEELLSKPWYIEVDMSKLIARI 353

                         330
                  ....*....|....*.
gi 1212621738 304 IRRIHNGESMSYLFRN 319
Cdd:PRK06827  354 IDALNHDVSLSKLLDP 369
PRK07199 PRK07199
ribose-phosphate diphosphokinase;
1-306 1.77e-14

ribose-phosphate diphosphokinase;


Pssm-ID: 235960 [Multi-domain]  Cd Length: 301  Bit Score: 72.66  E-value: 1.77e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738   1 MGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDvNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMRKRGSI 80
Cdd:PRK07199   26 VGRIELHRFPDGESYVRLDSPVAGRTVVLVCSLDRP-DEKLLPLLFAAEAARELGARRVGLVAPYLAYMRQDIAFHPGEA 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  81 VS-----KLLAsmmckAGLTHLITMD--LHQ-KEIQGFFNIPVDNLRASPFLLQYIQEEIPDyrnAVIVAKSPASAKRAQ 152
Cdd:PRK07199  105 ISqrhfaRLLS-----GSFDRLVTVDphLHRyPSLSEVYPIPAVVLSAAPAIAAWIRAHVPR---PLLIGPDEESEQWVA 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738 153 SFAERLRLGIAVIHGEaqdaesdlvdgRHSPpmvRSVAaihpsLEIPMLIPKEKPPITVVGDV--GGRiaiivddiiddv 230
Cdd:PRK07199  177 AVAERAGAPHAVLRKT-----------RHGD---RDVE-----ISLPDAAPWAGRTPVLVDDIvsTGR------------ 225

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1212621738 231 dSFLAAAETLKERGAYKIFVMATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQklqcpkikTVDISMILSEAIRR 306
Cdd:PRK07199  226 -TLIEAARQLRAAGAASPDCVVVHALFAGDAYSALAAAGIARVVSTDTVPHPSN--------AISLAPLLAEALRR 292
PLN02297 PLN02297
ribose-phosphate pyrophosphokinase
 20-154 8.99e-04

ribose-phosphate pyrophosphokinase


Pssm-ID: 177934 [Multi-domain]  Cd Length: 326  Bit Score: 40.44  E-value: 8.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1212621738  20 ESVRGKDVFIIQTVSKdvNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMRKRGSIVSKL-LASM-----MCKAG 93
Cdd:PLN02297   62 HGIRGQHVAFLASFSS--PAVIFEQLSVIYALPKLFVASFTLVLPFFPTGTSERVEREGDVATAFtLARIlsnipISRGG 139

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1212621738  94 LTHLITMDLHQKEIQGFFNipvDNLRAS-----PFLLQYIQeEIPDYRNAVIVAKSPASAKRAQSF 154
Cdd:PLN02297  140 PTSLVIFDIHALQERFYFG---DNVLPCfesgiPLLKKRLQ-QLPDSDNIVIAFPDDGAWKRFHKQ 201
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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