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Conserved domains on  [gi|198041728|ref|NP_001128246|]
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kinesin light chain 2 isoform 2 [Homo sapiens]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11419012)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

Gene Ontology:  GO:0005515
PubMed:  10517866|30708253

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
118-357 4.21e-28

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 112.79  E-value: 4.21e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 118 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrektl 197
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL--------DPDDAEALYNLGLAYLRLGRYEEALADYEQALEL----- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 198 gkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkfhPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIy 277
Cdd:COG0457   72 ---DPDDAEALNNLGLALQALGRYEEALEDYDKALELD--------PDDAEALYNLGLALLELGRYDEAIEAYERALEL- 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 278 atrlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEY 357
Cdd:COG0457  140 -------DPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLA 212
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
118-357 4.21e-28

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 112.79  E-value: 4.21e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 118 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrektl 197
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL--------DPDDAEALYNLGLAYLRLGRYEEALADYEQALEL----- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 198 gkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkfhPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIy 277
Cdd:COG0457   72 ---DPDDAEALNNLGLALQALGRYEEALEDYDKALELD--------PDDAEALYNLGLALLELGRYDEAIEAYERALEL- 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 278 atrlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEY 357
Cdd:COG0457  140 -------DPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLA 212
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 118-311 1.61e-19

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 92.67  E-value: 1.61e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 118 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTL 197
Cdd:NF040586 517 PRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLLSANNLARDLRELGRYAEALDLLEEALERYREVL 596

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 198 -GKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEI 276
Cdd:NF040586 597 gGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRRRFGPDHPDTLAAALSLANDLRALGDADEARELAREVLDR 676

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 198041728 277 YATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETL 311
Cdd:NF040586 677 YRRVLGEDHPFTLACRNNLAVLLRALGDPEEAREL 711
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 111-342 4.27e-18

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 88.05  E-value: 4.27e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 111 QHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD-VATMLNiLALVYRDQNKYKEAAHLLNDA 189
Cdd:NF040586 595 VLGGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRRRFGPDHPDtLAAALS-LANDLRALGDADEARELAREV 673

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 190 LAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHP---DVAKQLSN-LALLCQNQGKAEE 265
Cdd:NF040586 674 LDRYRRVLGEDHPFTLACRNNLAVLLRALGDPEEARELAEAALEGLRERLGPDHPytlAAAVNLANdLAALGDLDAALGE 753

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 198041728 266 VEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRahekeFGSVNGDNKPIWMHAEERE 342
Cdd:NF040586 754 EALERLRRLLGEDLRAGPDHPDTLACAANLALDLRATGRTEEAEELRADTLAR-----LRRVLGPDHPDTVAAREGR 825
TPR_12 pfam13424
Tetratricopeptide repeat;
161-237 5.79e-18

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 78.58  E-value: 5.79e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 198041728  161 DVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 237
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 134-407 1.58e-17

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 86.13  E-value: 1.58e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 134 QGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAI--REKTLGKDHPAVAATLNNL 211
Cdd:NF040586 405 RGDYESARDLAERALERWRERLGPDDRQTLRLRFHLANALRSLGRYEEARELDEDTLERqrRVLGLGEDHPHTLMTAGGL 484

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 212 AVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGkaeeveyYYRRALEI----YATR---LGPD 284
Cdd:NF040586 485 GADLRALGRFREALELDEETLERHRRVFGEDHPRTLRAANNLAVSLRLLG-------DYREALELdrevLRRRrrvLGPD 557

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 285 DPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEkefgSVNGDNKPIWMHAE-----------EREESKDKRRDSap 353
Cdd:NF040586 558 HPRTLLSANNLARDLRELGRYAEALDLLEEALERYRE----VLGGPDHPDTLRAAkslavalrragRLEEALELAEDT-- 631

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 198041728 354 YGEYGSWYKAckvDSPTVNTTLRSLGALYRRQGKLEAAHTL-EDCASRNRKQ-GLD 407
Cdd:NF040586 632 YERYRRRFGP---DHPDTLAAALSLANDLRALGDADEARELaREVLDRYRRVlGED 684
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 120-333 2.23e-16

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 82.66  E-value: 2.23e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 120 RLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD--HPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTL 197
Cdd:NF040586 433 TLRLRFHLANALRSLGRYEEARELDEDTLERQRRVLGLGedHPHTLMTAGGLGADLRALGRFREALELDEETLERHRRVF 512

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 198 GKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIY 277
Cdd:NF040586 513 GEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLLSANNLARDLRELGRYAEALDLLEEALERY 592

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 198041728 278 ATRL-GPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRahekeFGSVNGDNKP 333
Cdd:NF040586 593 REVLgGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYER-----YRRRFGPDHP 644
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 111-308 2.14e-15

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 79.58  E-value: 2.14e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 111 QHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKT-SGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDA 189
Cdd:NF040586 552 RVLGPDHPRTLLSANNLARDLRELGRYAEALDLLEEALERYREVlGGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDT 631

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 190 LAIREKTLGKDHP-AVAATLNnLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEY 268
Cdd:NF040586 632 YERYRRRFGPDHPdTLAAALS-LANDLRALGDADEARELAREVLDRYRRVLGEDHPFTLACRNNLAVLLRALGDPEEARE 710

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 198041728 269 YYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDA 308
Cdd:NF040586 711 LAEAALEGLRERLGPDHPYTLAAAVNLANDLAALGDLDAA 750
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 119-313 7.06e-11

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 62.35  E-value: 7.06e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728  119 ARLRTlhNLVIQYASQGRYEvavplckQALEDLEKTSGHDhPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrektlg 198
Cdd:TIGR02521  31 AKIRV--QLALGYLEQGDLE-------VAKENLDKALEHD-PDDYLAYLALALYYQQLGELEKAEDSFRRALTL------ 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728  199 kdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEirekvlGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIya 278
Cdd:TIGR02521  95 --NPNNGDVLNNYGTFLCQQGKYEQAMQQFEQAIE------DPLYPQPARSLENAGLCALKAGDFDKAEKYLTRALQI-- 164

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 198041728  279 trlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYK 313
Cdd:TIGR02521 165 ------DPQRPESLLELAELYYLRGQYKDARAYLE 193
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 205-237 1.73e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 38.97  E-value: 1.73e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 198041728   205 AATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 237
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 214-394 1.56e-03

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 41.44  E-value: 1.56e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 214 LYgKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEV---------------------EY---- 268
Cdd:NF040586 402 LY-LRGDYESARDLAERALERWRERLGPDDRQTLRLRFHLANALRSLGRYEEAreldedtlerqrrvlglgedhPHtlmt 480

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 269 ------------YYRRALEI-------YATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRahekeFGSVNG 329
Cdd:NF040586 481 agglgadlralgRFREALELdeetlerHRRVFGEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRR-----RRRVLG 555

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 198041728 330 DNKP----IWMH-------AEEREESKDKRRDSAPYGEygswYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTL 394
Cdd:NF040586 556 PDHPrtllSANNlardlreLGRYAEALDLLEEALERYR----EVLGGPDHPDTLRAAKSLAVALRRAGRLEEALEL 627
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 131-321 7.86e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 38.38  E-value: 7.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 131 YASQGRYEVAVPLCKQALEdlektsghDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIR-----EKTL-------G 198
Cdd:cd24142   10 LLDQGNFELALKFLQRALE--------LEPNNVEALELLGEILLELGDVEEAREVLLRAIELDpdggyEKYLylgqlsgG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 199 KDhpAVAATLNNLAVLYGKRGKYKEAEPLCKRALEirekvlgkfhpDVAKQLSNlAL----------LCQNQGKAEEVEY 268
Cdd:cd24142   82 EE--ALQYYEKGIEILEEELQALQAASAEAEEEAE-----------ELKRKLSS-ALcalaeiymtdLCDEPDAEQRCEE 147

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 198041728 269 YYRRALEIYatrlgPDDPNVAKTknnLASCYLKQGKYQDAetlyKEILTRAHE 321
Cdd:cd24142  148 LITKALELD-----PTNPEALQT---LASLRISQQRPDEA----KEALRRSLE 188
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
118-357 4.21e-28

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 112.79  E-value: 4.21e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 118 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrektl 197
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL--------DPDDAEALYNLGLAYLRLGRYEEALADYEQALEL----- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 198 gkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkfhPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIy 277
Cdd:COG0457   72 ---DPDDAEALNNLGLALQALGRYEEALEDYDKALELD--------PDDAEALYNLGLALLELGRYDEAIEAYERALEL- 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 278 atrlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGDNKPIWMHAEEREESKDKRRDSAPYGEY 357
Cdd:COG0457  140 -------DPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLA 212
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 116-319 1.42e-19

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 92.36  E-value: 1.42e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 116 EIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKtsGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrek 195
Cdd:COG3914   33 EAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAA--AAALLLLAALLELAALLLQALGRYEEALALYRRALAL--- 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 196 tlgkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkfHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALE 275
Cdd:COG3914  108 -----NPDNAEALFNLGNLLLALGRLEEALAALRRALAL--------NPDFAEAYLNLGEALRRLGRLEEAIAALRRALE 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 198041728 276 IyatrlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRA 319
Cdd:COG3914  175 L--------DPDNAEALNNLGNALQDLGRLEEAIAAYRRALELD 210
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 118-311 1.61e-19

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 92.67  E-value: 1.61e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 118 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTL 197
Cdd:NF040586 517 PRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLLSANNLARDLRELGRYAEALDLLEEALERYREVL 596

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 198 -GKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEI 276
Cdd:NF040586 597 gGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRRRFGPDHPDTLAAALSLANDLRALGDADEARELAREVLDR 676

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 198041728 277 YATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETL 311
Cdd:NF040586 677 YRRVLGEDHPFTLACRNNLAVLLRALGDPEEAREL 711
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 111-342 4.27e-18

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 88.05  E-value: 4.27e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 111 QHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD-VATMLNiLALVYRDQNKYKEAAHLLNDA 189
Cdd:NF040586 595 VLGGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRRRFGPDHPDtLAAALS-LANDLRALGDADEARELAREV 673

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 190 LAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHP---DVAKQLSN-LALLCQNQGKAEE 265
Cdd:NF040586 674 LDRYRRVLGEDHPFTLACRNNLAVLLRALGDPEEARELAEAALEGLRERLGPDHPytlAAAVNLANdLAALGDLDAALGE 753

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 198041728 266 VEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRahekeFGSVNGDNKPIWMHAEERE 342
Cdd:NF040586 754 EALERLRRLLGEDLRAGPDHPDTLACAANLALDLRATGRTEEAEELRADTLAR-----LRRVLGPDHPDTVAAREGR 825
TPR_12 pfam13424
Tetratricopeptide repeat;
161-237 5.79e-18

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 78.58  E-value: 5.79e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 198041728  161 DVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 237
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 134-407 1.58e-17

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 86.13  E-value: 1.58e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 134 QGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAI--REKTLGKDHPAVAATLNNL 211
Cdd:NF040586 405 RGDYESARDLAERALERWRERLGPDDRQTLRLRFHLANALRSLGRYEEARELDEDTLERqrRVLGLGEDHPHTLMTAGGL 484

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 212 AVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGkaeeveyYYRRALEI----YATR---LGPD 284
Cdd:NF040586 485 GADLRALGRFREALELDEETLERHRRVFGEDHPRTLRAANNLAVSLRLLG-------DYREALELdrevLRRRrrvLGPD 557

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 285 DPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEkefgSVNGDNKPIWMHAE-----------EREESKDKRRDSap 353
Cdd:NF040586 558 HPRTLLSANNLARDLRELGRYAEALDLLEEALERYRE----VLGGPDHPDTLRAAkslavalrragRLEEALELAEDT-- 631

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 198041728 354 YGEYGSWYKAckvDSPTVNTTLRSLGALYRRQGKLEAAHTL-EDCASRNRKQ-GLD 407
Cdd:NF040586 632 YERYRRRFGP---DHPDTLAAALSLANDLRALGDADEARELaREVLDRYRRVlGED 684
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 118-321 4.71e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 81.31  E-value: 4.71e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 118 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEdlektsghDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrektl 197
Cdd:COG2956   73 PDRAEALLELAQDYLKAGLLDRAEELLEKLLE--------LDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKL----- 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 198 gkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkfHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIy 277
Cdd:COG2956  140 ---GPENAHAYCELAELYLEQGDYDEAIEALEKALKL--------DPDCARALLLLAELYLEQGDYEEAIAALERALEQ- 207

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 198041728 278 atrlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHE 321
Cdd:COG2956  208 -------DPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS 244
TPR_12 pfam13424
Tetratricopeptide repeat;
204-277 7.90e-17

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 75.12  E-value: 7.90e-17
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 198041728  204 VAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIY 277
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALA 75
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 120-333 2.23e-16

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 82.66  E-value: 2.23e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 120 RLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHD--HPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTL 197
Cdd:NF040586 433 TLRLRFHLANALRSLGRYEEARELDEDTLERQRRVLGLGedHPHTLMTAGGLGADLRALGRFREALELDEETLERHRRVF 512

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 198 GKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIY 277
Cdd:NF040586 513 GEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLGPDHPRTLLSANNLARDLRELGRYAEALDLLEEALERY 592

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 198041728 278 ATRL-GPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRahekeFGSVNGDNKP 333
Cdd:NF040586 593 REVLgGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYER-----YRRRFGPDHP 644
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 131-321 9.65e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 77.46  E-value: 9.65e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 131 YASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTlgkdhpavAATLNN 210
Cdd:COG2956   52 YRRRGEYDRAIRIHQKLLER--------DPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDD--------AEALRL 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 211 LAVLYGKRGKYKEAEPLCKRALEIrekvlgkfHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIyatrlgpdDPNVAK 290
Cdd:COG2956  116 LAEIYEQEGDWEKAIEVLERLLKL--------GPENAHAYCELAELYLEQGDYDEAIEALEKALKL--------DPDCAR 179

                        170       180       190
                 ....*....|....*....|....*....|.
gi 198041728 291 TKNNLASCYLKQGKYQDAETLYKEILTRAHE 321
Cdd:COG2956  180 ALLLLAELYLEQGDYEEAIAALERALEQDPD 210
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 111-308 2.14e-15

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 79.58  E-value: 2.14e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 111 QHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKT-SGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDA 189
Cdd:NF040586 552 RVLGPDHPRTLLSANNLARDLRELGRYAEALDLLEEALERYREVlGGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDT 631

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 190 LAIREKTLGKDHP-AVAATLNnLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEY 268
Cdd:NF040586 632 YERYRRRFGPDHPdTLAAALS-LANDLRALGDADEARELAREVLDRYRRVLGEDHPFTLACRNNLAVLLRALGDPEEARE 710

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 198041728 269 YYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDA 308
Cdd:NF040586 711 LAEAALEGLRERLGPDHPYTLAAAVNLANDLAALGDLDAA 750
TPR_12 pfam13424
Tetratricopeptide repeat;
120-195 4.84e-15

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 70.11  E-value: 4.84e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 198041728  120 RLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREK 195
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 130-401 3.48e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 72.84  E-value: 3.48e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 130 QYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTlgkdhpavAATLN 209
Cdd:COG2956   17 NYLLNGQPDKAIDLLEEALEL--------DPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDR--------AEALL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 210 NLAVLYGKRGKYKEAEPLCKRALEIRekvlgkfhPDVAKQLSNLALLCQNQGKaeeveyyYRRALEiYATRLGPDDPNVA 289
Cdd:COG2956   81 ELAQDYLKAGLLDRAEELLEKLLELD--------PDDAEALRLLAEIYEQEGD-------WEKAIE-VLERLLKLGPENA 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 290 KTKNNLASCYLKQGKYQDAETLYKEILtrahekefgSVNGDNKPIWMHAEEREESKDKrrdsapYGEYGSWYKACKVDSP 369
Cdd:COG2956  145 HAYCELAELYLEQGDYDEAIEALEKAL---------KLDPDCARALLLLAELYLEQGD------YEEAIAALERALEQDP 209

                        250       260       270
                 ....*....|....*....|....*....|...
gi 198041728 370 TVNTTLRSLGALYRRQGKLEAA-HTLEDCASRN 401
Cdd:COG2956  210 DYLPALPRLAELYEKLGDPEEAlELLRKALELD 242
TPR_12 pfam13424
Tetratricopeptide repeat;
245-319 2.94e-13

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 65.10  E-value: 2.94e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 198041728  245 DVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRA 319
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALA 75
TPR_10 pfam13374
Tetratricopeptide repeat;
204-245 7.24e-13

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 62.90  E-value: 7.24e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 198041728  204 VAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPD 245
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHPD 42
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 119-278 1.04e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 65.60  E-value: 1.04e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 119 ARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrektlg 198
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALEL--------DPDNPEAFALLGEILLQLGDLDEAIVLLHEALEL------ 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 199 kdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKvlgkfHPDVakqLSNLALLCQNQGKAEEVEYYYRRALEIYA 278
Cdd:COG4783   68 --DPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPE-----HPEA---YLRLARAYRALGRPDEAIAALEKALELDP 137
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 130-321 2.84e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 69.25  E-value: 2.84e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 130 QYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEA-AHLLNDALAIREKTLGKDHPAVAATL 208
Cdd:COG3914    2 AAAALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAaAAALLALAAGEAAAAAAALLLLAALL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 209 NNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkfHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIyatrlgpdDPNV 288
Cdd:COG3914   82 ELAALLLQALGRYEEALALYRRALAL--------NPDNAEALFNLGNLLLALGRLEEALAALRRALAL--------NPDF 145

                        170       180       190
                 ....*....|....*....|....*....|...
gi 198041728 289 AKTKNNLASCYLKQGKYQDAETLYKEILTRAHE 321
Cdd:COG3914  146 AEAYLNLGEALRRLGRLEEAIAALRRALELDPD 178
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 169-321 4.28e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 63.67  E-value: 4.28e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 169 LALVYRDQNKYKEAAHLLNDALairektlgKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkfHPDVAK 248
Cdd:COG4783   10 LAQALLLAGDYDEAEALLEKAL--------ELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALEL--------DPDEPE 73

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 198041728 249 QLSNLALLCQNQGKAEEVEYYYRRALEIYatrlgPDDPNVAktkNNLASCYLKQGKYQDAETLYKEILTRAHE 321
Cdd:COG4783   74 ARLNLGLALLKAGDYDEALALLEKALKLD-----PEHPEAY---LRLARAYRALGRPDEAIAALEKALELDPD 138
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 168-391 4.61e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 66.68  E-value: 4.61e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 168 ILALVYRDQNKYKEAAHLLNDALAIrektlgkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkfHPDVA 247
Cdd:COG2956   13 FKGLNYLLNGQPDKAIDLLEEALEL--------DPETVEAHLALGNLYRRRGEYDRAIRIHQKLLER--------DPDRA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 248 KQLSNLALLCQNQGKAEEVEYYYRRALEIyatrlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTrahekefgsV 327
Cdd:COG2956   77 EALLELAQDYLKAGLLDRAEELLEKLLEL--------DPDDAEALRLLAEIYEQEGDWEKAIEVLERLLK---------L 139

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 198041728 328 NGDNKPIWMH-AEEREESKDKrrDSApygeYGSWYKACKVDsPTVNTTLRSLGALYRRQGKLEAA 391
Cdd:COG2956  140 GPENAHAYCElAELYLEQGDY--DEA----IEALEKALKLD-PDCARALLLLAELYLEQGDYEEA 197
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
118-309 4.86e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 63.10  E-value: 4.86e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 118 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIRektl 197
Cdd:COG0457   73 PDDAEALNNLGLALQALGRYEEALEDYDKALEL--------DPDDAEALYNLGLALLELGRYDEAIEAYERALELD---- 140

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 198 gkdhPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREkvlgKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIY 277
Cdd:COG0457  141 ----PDDADALYNLGIALEKLGRYEEALELLEKLEAAAL----AALLAAALGEAALALAAAEVLLALLLALEQALRKKLA 212

                        170       180       190
                 ....*....|....*....|....*....|..
gi 198041728 278 ATRLGPDDPNVAKTKNNLASCYLKQGKYQDAE 309
Cdd:COG0457  213 ILTLAALAELLLLALALLLALRLAALALYQYR 244
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 157-319 6.95e-11

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 60.74  E-value: 6.95e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 157 HDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIre 236
Cdd:COG5010    6 GFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQL-- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 237 kvlgkfHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIyatrlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYKEIL 316
Cdd:COG5010   84 ------DPNNPELYYNLALLYSRSGDKDEAKEYYEKALAL--------SPDNPNAYSNLAALLLSLGQDDEAKAALQRAL 149


                 ...
gi 198041728 317 TRA 319
Cdd:COG5010  150 GTS 152
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 119-313 7.06e-11

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 62.35  E-value: 7.06e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728  119 ARLRTlhNLVIQYASQGRYEvavplckQALEDLEKTSGHDhPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrektlg 198
Cdd:TIGR02521  31 AKIRV--QLALGYLEQGDLE-------VAKENLDKALEHD-PDDYLAYLALALYYQQLGELEKAEDSFRRALTL------ 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728  199 kdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEirekvlGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIya 278
Cdd:TIGR02521  95 --NPNNGDVLNNYGTFLCQQGKYEQAMQQFEQAIE------DPLYPQPARSLENAGLCALKAGDFDKAEKYLTRALQI-- 164

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 198041728  279 trlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYK 313
Cdd:TIGR02521 165 ------DPQRPESLLELAELYYLRGQYKDARAYLE 193
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
172-281 7.39e-11

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 58.64  E-value: 7.39e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 172 VYRDQNKYKEAAHLLNDALAIrektlgkdHPAVAATLNNLAVLYGKRGKYKEAEPLcKRALEIrekvlgkfHPDVAKQLS 251
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALEL--------DPDNADALNNLGLLLLEQGRYDEAIAL-EKALKL--------DPNNAEALL 63

                         90       100       110
                 ....*....|....*....|....*....|
gi 198041728 252 NLALLCQNQGKAEEVEYYYRRALEIYATRL 281
Cdd:COG3063   64 NLAELLLELGDYDEALAYLERALELDPSAL 93
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
214-316 2.04e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 57.49  E-value: 2.04e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 214 LYGKRGKYKEAEPLCKRALEIrekvlgkfHPDVAKQLSNLALLCQNQGKAEEVEYYyRRALEIyatrlgpdDPNVAKTKN 293
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALEL--------DPDNADALNNLGLLLLEQGRYDEAIAL-EKALKL--------DPNNAEALL 63

                         90       100
                 ....*....|....*....|...
gi 198041728 294 NLASCYLKQGKYQDAETLYKEIL 316
Cdd:COG3063   64 NLAELLLELGDYDEALAYLERAL 86
TPR_10 pfam13374
Tetratricopeptide repeat;
162-202 2.55e-10

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 55.59  E-value: 2.55e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 198041728  162 VATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKDHP 202
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHP 41
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 118-276 5.93e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 58.05  E-value: 5.93e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 118 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrektl 197
Cdd:COG5010    9 RLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQL----- 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 198041728 198 gkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkfHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEI 276
Cdd:COG5010   84 ---DPNNPELYYNLALLYSRSGDKDEAKEYYEKALAL--------SPDNPNAYSNLAALLLSLGQDDEAKAALQRALGT 151
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
131-239 6.89e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 55.95  E-value: 6.89e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 131 YASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLlNDALAIrektlgkdHPAVAATLNN 210
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALEL--------DPDNADALNNLGLLLLEQGRYDEAIAL-EKALKL--------DPNNAEALLN 64

                         90       100
                 ....*....|....*....|....*....
gi 198041728 211 LAVLYGKRGKYKEAEPLCKRALEIREKVL 239
Cdd:COG3063   65 LAELLLELGDYDEALAYLERALELDPSAL 93
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 203-319 1.05e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 56.74  E-value: 1.05e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 203 AVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkfHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYatrlg 282
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALEL--------DPDNPEAFALLGEILLQLGDLDEAIVLLHEALELD----- 68

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 198041728 283 PDDPNVAktkNNLASCYLKQGKYQDAETLYKEILTRA 319
Cdd:COG4783   69 PDEPEAR---LNLGLALLKAGDYDEALALLEKALKLD 102
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 199-319 2.79e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 55.40  E-value: 2.79e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 199 KDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkfhPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIya 278
Cdd:COG4235   11 AANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLD--------PDNADALLDLAEALLAAGDTEEAEELLERALAL-- 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 198041728 279 trlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRA 319
Cdd:COG4235   81 ------DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALL 115
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
126-313 3.39e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 57.23  E-value: 3.39e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 126 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIRektlgkdhPAVA 205
Cdd:COG4785   36 ALAIALADLALALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELD--------PDLA 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 206 ATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkfhPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEiyatrLGPDD 285
Cdd:COG4785  108 EAYNNRGLAYLLLGDYDAALEDFDRALELD--------PDYAYAYLNRGIALYYLGRYELAIADLEKALE-----LDPND 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 198041728 286 P-------------NVAKTKNNL----ASCYLKQGKYQDAETLYK 313
Cdd:COG4785  175 PeralwlylaerklDPEKALALLledwATAYLLQGDTEEARELFK 219
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
241-391 5.40e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 56.94  E-value: 5.40e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 241 KFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIyatrlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYKEILtrah 320
Cdd:COG0457    2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL--------DPDDAEALYNLGLAYLRLGRYEEALADYEQAL---- 69

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 198041728 321 ekefgSVNGDNKPIWMHAEEREESKDKRRDSAPYgeygsWYKACKVDsPTVNTTLRSLGALYRRQGKLEAA 391
Cdd:COG0457   70 -----ELDPDDAEALNNLGLALQALGRYEEALED-----YDKALELD-PDDAEALYNLGLALLELGRYDEA 129
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 165-391 6.22e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.47  E-value: 6.22e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 165 MLNILALVYRDQNKYKEAAHLLNDALAIREktlgkDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREkvLGKFHP 244
Cdd:COG3914    3 AAALLALAALAAAALLAAAAAAELALAAEL-----EAAALAAALGLALLLLAALAEAAAAALLALAAGEAAA--AAAALL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 245 DVAKQLSNLALLCQNQGKAEEVEYYYRRALEIyatrlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYKEILtrahekef 324
Cdd:COG3914   76 LLAALLELAALLLQALGRYEEALALYRRALAL--------NPDNAEALFNLGNLLLALGRLEEALAALRRAL-------- 139

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 198041728 325 gSVNGDNKPIW-------MHAEEREESKDkrrdsapygeygSWYKACKVDsPTVNTTLRSLGALYRRQGKLEAA 391
Cdd:COG3914  140 -ALNPDFAEAYlnlgealRRLGRLEEAIA------------ALRRALELD-PDNAEALNNLGNALQDLGRLEEA 199
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 158-317 1.31e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 57.79  E-value: 1.31e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728  158 DHPDVATMLNILALVYRDQNKYKEAAHLLNDALairektlgKDHPAVAATLNNLAVLYGKRgKYKEAEPLCKRALEIRek 237
Cdd:TIGR02917 765 THPNDAVLRTALAELYLAQKDYDKAIKHYQTVV--------KKAPDNAVVLNNLAWLYLEL-KDPRALEYAERALKLA-- 833

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728  238 vlgkfhPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIyatrlGPDDPNVaktKNNLASCYLKQGKYQDAETLYKEILT 317
Cdd:TIGR02917 834 ------PNIPAILDTLGWLLVEKGEADRALPLLRKAVNI-----APEAAAI---RYHLALALLATGRKAEARKELDKLLN 899
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 146-296 3.21e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 52.32  E-value: 3.21e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 146 QALEDLEKTSGHDHPDVATMLNiLALVYRDQNKYKEAAHLLNDALAIRektlgkdhPAVAATLNNLAVLYGKRGKYKEAE 225
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLL-LGRAYLRLGRYDEALAAYEKALRLD--------PDNADALLDLAEALLAAGDTEEAE 71

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 198041728 226 PLCKRALEIrekvlgkfHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEiyatrLGPDDPNVAKTKNNLA 296
Cdd:COG4235   72 ELLERALAL--------DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLA-----LLPADAPARLLEASIA 129
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
36-275 1.25e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 52.61  E-value: 1.25e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728  36 RALLAPLVAPEAGEAEPGSQERCILLRRSLEA--IELGLGEAQEEKGDVPKDtLDDLFPNEDEQSPAPSPgggdvsgqhg 113
Cdd:COG4785    1 LYALALALLLALALAAAAASKAAILLAALLFAavLALAIALADLALALAAAA-LAAAALAAERIDRALAL---------- 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 114 gyeiPARLRTLHNLVIQYASQGRYEVAVPLCKQALEdlektsghDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIR 193
Cdd:COG4785   70 ----PDLAQLYYERGVAYDSLGDYDLAIADFDQALE--------LDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELD 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 194 ektlgkdhPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREK----------VLGKFHPDVAKQL--SNLALLCQNQG 261
Cdd:COG4785  138 --------PDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNdperalwlylAERKLDPEKALALllEDWATAYLLQG 209

                        250
                 ....*....|....
gi 198041728 262 KAEEVEYYYRRALE 275
Cdd:COG4785  210 DTEEARELFKLALA 223
TPR_10 pfam13374
Tetratricopeptide repeat;
121-161 7.02e-07

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 45.96  E-value: 7.02e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 198041728  121 LRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPD 161
Cdd:pfam13374   2 ASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHPD 42
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
169-351 8.69e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 49.91  E-value: 8.69e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 169 LALVYRDQNKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRekvlgkfhPDVAK 248
Cdd:COG4785   37 LAIALADLALALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELD--------PDLAE 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 249 QLSNLALLCQNQGKAEEVEYYYRRALEIyatrlgpdDPNVAKTKNNLASCYLKQGKYQDAEtlykEILTRAHEKefgSVN 328
Cdd:COG4785  109 AYNNRGLAYLLLGDYDAALEDFDRALEL--------DPDYAYAYLNRGIALYYLGRYELAI----ADLEKALEL---DPN 173

                        170       180
                 ....*....|....*....|...
gi 198041728 329 GDNKPIWMHAEEREESKDKRRDS 351
Cdd:COG4785  174 DPERALWLYLAERKLDPEKALAL 196
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 131-321 1.21e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 51.62  E-value: 1.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728  131 YASQGRYEVAVPLCKQALEdLEKTSGhdhpdvATMLniLALVYRDQNKYKEAAHLLNDALairektlgKDHPAVAATLNN 210
Cdd:TIGR02917 713 YLRQKDYPAAIQAYRKALK-RAPSSQ------NAIK--LHRALLASGNTAEAVKTLEAWL--------KTHPNDAVLRTA 775

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728  211 LAVLYGKRGKYKEAEPLCKRALEIrekvlgkfHPDVAKQLSNLALLCQnQGKAEEVEYYYRRALEiyatrLGPDDPNVAK 290
Cdd:TIGR02917 776 LAELYLAQKDYDKAIKHYQTVVKK--------APDNAVVLNNLAWLYL-ELKDPRALEYAERALK-----LAPNIPAILD 841

                         170       180       190
                  ....*....|....*....|....*....|.
gi 198041728  291 TknnLASCYLKQGKYQDAETLYKEILTRAHE 321
Cdd:TIGR02917 842 T---LGWLLVEKGEADRALPLLRKAVNIAPE 869
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 118-234 1.89e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.49  E-value: 1.89e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 118 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEdlektsghDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAirektL 197
Cdd:COG4783   35 PDNPEAFALLGEILLQLGDLDEAIVLLHEALE--------LDPDEPEARLNLGLALLKAGDYDEALALLEKALK-----L 101

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 198041728 198 GKDHPAVaatLNNLAVLYGKRGKYKEAEPLCKRALEI 234
Cdd:COG4783  102 DPEHPEA---YLRLARAYRALGRPDEAIAALEKALEL 135
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 118-235 3.14e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.96  E-value: 3.14e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 118 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDlektsghdHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrektl 197
Cdd:COG2956  175 PDCARALLLLAELYLEQGDYEEAIAALERALEQ--------DPDYLPALPRLAELYEKLGDPEEALELLRKALEL----- 241

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 198041728 198 gkdHPAVAAtLNNLAVLYGKRGKYKEAEPLCKRALEIR 235
Cdd:COG2956  242 ---DPSDDL-LLALADLLERKEGLEAALALLERQLRRH 275
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 118-234 3.46e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.54  E-value: 3.46e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 118 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEdLEktsghdhPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrektl 197
Cdd:COG4235   14 PNDAEGWLLLGRAYLRLGRYDEALAAYEKALR-LD-------PDNADALLDLAEALLAAGDTEEAEELLERALAL----- 80

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 198041728 198 gkdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEI 234
Cdd:COG4235   81 ---DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLAL 114
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 217-318 4.08e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 45.75  E-value: 4.08e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 217 KRGKYKEAEPLCKRALeirekvlgKFHPD---VAKQLSNLALLCQNQGKAEEVEYYYRRALEIYatrlgPDDPNVAKTKN 293
Cdd:COG1729    5 KAGDYDEAIAAFKAFL--------KRYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRY-----PDSPKAPDALL 71

                         90       100
                 ....*....|....*....|....*
gi 198041728 294 NLASCYLKQGKYQDAETLYKEILTR 318
Cdd:COG1729   72 KLGLSYLELGDYDKARATLEELIKK 96
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 145-319 4.69e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 49.70  E-value: 4.69e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728  145 KQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLgkdhPAVAAtlnnLAVLYGKRGKYKEA 224
Cdd:TIGR02917 107 QQVLDELPGKTLLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSL----YAKLG----LAQLALAENRFDEA 178

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728  225 EPLCKRALEIrekvlgkfHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIyatrlgpdDPNVAKTKNNLASCYLKQGK 304
Cdd:TIGR02917 179 RALIDEVLTA--------DPGNVDALLLKGDLLLSLGNIELALAAYRKAIAL--------RPNNIAVLLALATILIEAGE 242

                         170
                  ....*....|....*
gi 198041728  305 YQDAETLYKEILTRA 319
Cdd:TIGR02917 243 FEEAEKHADALLKKA 257
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 118-279 1.55e-05

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 47.31  E-value: 1.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728  118 PARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKtsgHDHPDVATM-LNILALVYRDQNKYKEAAHLLNDALAIREKT 196
Cdd:pfam17874  37 LARGLATFVLGEAYLCLGDLDAALQAMREAEALARR---ADSPHVTLWaLLQQGEILRAQGRLHQALETYQQALQLARDH 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728  197 LGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvLGKFHPDVAKQ-LSNLALLCQNQGKAEEVEYYYRRALE 275
Cdd:pfam17874 114 GLQHLPLHGFLLVGLADLLYEWNDLEEAEQHAQQGIQL----GRQWEPDAAVDaYVLLARIALAQGELEEALTLLRRAEL 189


                  ....
gi 198041728  276 IYAT 279
Cdd:pfam17874 190 LARQ 193
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 126-322 2.09e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.39  E-value: 2.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728  126 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDhPDVATMLNILALVYRDQNKykeaahlLNDALAIREKtLGKDHPAVA 205
Cdd:TIGR02917 395 ENAAARTQLGISKLSQGDPSEAIADLETAAQLD-PELGRADLLLILSYLRSGQ-------FDKALAAAKK-LEKKQPDNA 465

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728  206 ATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvlgkfHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIyatrlgpdD 285
Cdd:TIGR02917 466 SLHNLLGAIYLGKGDLAKAREAFEKALSI--------EPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTI--------D 529

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 198041728  286 PNVAKTKNNLASCYLKQGKYQDAetlyKEILTRAHEK 322
Cdd:TIGR02917 530 PKNLRAILALAGLYLRTGNEEEA----VAWLEKAAEL 562
TPR_1 pfam00515
Tetratricopeptide repeat;
205-237 3.55e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 40.87  E-value: 3.55e-05
                          10        20        30
                  ....*....|....*....|....*....|...
gi 198041728  205 AATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 237
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
TPR_12 pfam13424
Tetratricopeptide repeat;
288-404 4.13e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.99  E-value: 4.13e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728  288 VAKTKNNLASCYLKQGKYQDAETLYKEILTRAhEKEFGSvngdnkpiwmhaeereeskdkrrdsapygeygswykackvD 367
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIA-RRLLGP----------------------------------------D 40

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 198041728  368 SPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRNRKQ 404
Cdd:pfam13424  41 HPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR_10 pfam13374
Tetratricopeptide repeat;
246-287 1.18e-04

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 39.41  E-value: 1.18e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 198041728  246 VAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPN 287
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALAIRERVLGPDHPD 42
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 169-234 1.23e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 40.40  E-value: 1.23e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 198041728  169 LALVYRDQNKYKEAAHLLNDALAirektLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEI 234
Cdd:pfam13432   3 LARAALRAGDYDDAAAALEAALA-----RFPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRA 63
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 205-237 1.73e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 38.97  E-value: 1.73e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 198041728   205 AATLNNLAVLYGKRGKYKEAEPLCKRALEIREK 237
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR_7 pfam13176
Tetratricopeptide repeat;
207-241 1.90e-04

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 38.68  E-value: 1.90e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 198041728  207 TLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGK 241
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYDR 35
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 243-321 1.94e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 41.53  E-value: 1.94e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 198041728 243 HPDVAKQLSNLALLCQNQGKAEEVEYYYRRALeiyatRLGPDDPNVaktKNNLASCYLKQGKYQDAETLYKEILTRAHE 321
Cdd:COG4235   13 NPNDAEGWLLLGRAYLRLGRYDEALAAYEKAL-----RLDPDNADA---LLDLAEALLAAGDTEEAEELLERALALDPD 83
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 173-297 2.13e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 40.75  E-value: 2.13e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 173 YRDQNKYKEAAHLLNDALAirektLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKvlgkfHPDVAKQLSN 252
Cdd:COG1729    3 LLKAGDYDEAIAAFKAFLK-----RYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPD-----SPKAPDALLK 72

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 198041728 253 LALLCQNQGKAEEVEYYYRRALEIYatrlgPDDPNVAKTKNNLAS 297
Cdd:COG1729   73 LGLSYLELGDYDKARATLEELIKKY-----PDSEAAKEARARLAR 112
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 130-323 3.43e-04

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 43.07  E-value: 3.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728  130 QYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAirektLGKDHPAVAATLN 209
Cdd:pfam17874  89 ILRAQGRLHQALETYQQALQLARDHGLQHLPLHGFLLVGLADLLYEWNDLEEAEQHAQQGIQ-----LGRQWEPDAAVDA 163

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728  210 NLAVLYGK--RGKYKEAEPLCKRALEIREKvlGKFHPD----VAKQLSNLALLCQNQGKAeeveyyyRRALEIYATRLGP 283
Cdd:pfam17874 164 YVLLARIAlaQGELEEALTLLRRAELLARQ--SFFHVDwlanAERVRVRLWLARGDLRAA-------VRWLRAAEPPSDA 234

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 198041728  284 DDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKE 323
Cdd:pfam17874 235 DNHFLERELRNLARVLLALGRFDDALSLLERLQNLAEQLG 274
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 145-319 4.00e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.15  E-value: 4.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728  145 KQALEDLEKTSGHDhPDVATMLNILALVYRDQNKYKEAAHLLNDALAIrektlgkdHPAVAATLNNLAVLYGKRGKYKEA 224
Cdd:TIGR02917 618 NKAVSSFKKLLALQ-PDSALALLLLADAYAVMKNYAKAITSLKRALEL--------KPDNTEAQIGLAQLLLAAKRTESA 688

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728  225 EPLCKRALEIREKvlgkfHPDVAKQLSNLALLcqnQGKAEEVEYYYRRALEIYAT-----RLG----------------- 282
Cdd:TIGR02917 689 KKIAKSLQKQHPK-----AALGFELEGDLYLR---QKDYPAAIQAYRKALKRAPSsqnaiKLHrallasgntaeavktle 760

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 198041728  283 ---PDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRA 319
Cdd:TIGR02917 761 awlKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKA 800
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
118-197 4.02e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.77  E-value: 4.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 118 PARLRTLHNLVIQYASQGRYEVAVPLcKQALEdlektsghDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTL 197
Cdd:COG3063   23 PDNADALNNLGLLLLEQGRYDEAIAL-EKALK--------LDPNNAEALLNLAELLLELGDYDEALAYLERALELDPSAL 93
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 160-279 1.45e-03

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 41.51  E-value: 1.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728  160 PDVATMLNILALVYRDQNKYKEAAHLLNDALAIREKTLGKdHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIrekvl 239
Cdd:TIGR00990 464 PEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELEKETKPM-YMNVLPLINKALALFQWKQDFIEAENLCEKALII----- 537

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 198041728  240 gkfHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYAT 279
Cdd:TIGR00990 538 ---DPECDIAVATMAQLLLQQGDVDEALKLFERAAELART 574
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 214-394 1.56e-03

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 41.44  E-value: 1.56e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 214 LYgKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEV---------------------EY---- 268
Cdd:NF040586 402 LY-LRGDYESARDLAERALERWRERLGPDDRQTLRLRFHLANALRSLGRYEEAreldedtlerqrrvlglgedhPHtlmt 480

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 269 ------------YYRRALEI-------YATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRahekeFGSVNG 329
Cdd:NF040586 481 agglgadlralgRFREALELdeetlerHRRVFGEDHPRTLRAANNLAVSLRLLGDYREALELDREVLRR-----RRRVLG 555

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 198041728 330 DNKP----IWMH-------AEEREESKDKRRDSAPYGEygswYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTL 394
Cdd:NF040586 556 PDHPrtllSANNlardlreLGRYAEALDLLEEALERYR----EVLGGPDHPDTLRAAKSLAVALRRAGRLEEALEL 627
TPR_10 pfam13374
Tetratricopeptide repeat;
288-325 1.59e-03

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 36.33  E-value: 1.59e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 198041728  288 VAKTKNNLASCYLKQGKYQDAETLYKEILTRaHEKEFG 325
Cdd:pfam13374   1 TASSLNNLANALRAQGRYDEAEELLEEALAI-RERVLG 37
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 289-321 2.97e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.50  E-value: 2.97e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 198041728   289 AKTKNNLASCYLKQGKYQDAETLYKEILTRAHE 321
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR_1 pfam00515
Tetratricopeptide repeat;
289-321 3.90e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.09  E-value: 3.90e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 198041728  289 AKTKNNLASCYLKQGKYQDAETLYKEILTRAHE 321
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 131-192 5.51e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 35.77  E-value: 5.51e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 198041728  131 YASQGRYEVAVPLCKQALEdlektSGHDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAI 192
Cdd:pfam13432   7 ALRAGDYDDAAAALEAALA-----RFPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRA 63
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 129-224 6.08e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 36.89  E-value: 6.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 129 IQYASQGRYEVAVPLCKQALEDLEktsghDHPDVATMLNILALVYRDQNKYKEAAHLLNDALairekTLGKDHPAVAATL 208
Cdd:COG1729    1 KALLKAGDYDEAIAAFKAFLKRYP-----NSPLAPDALYWLGEAYYALGDYDEAAEAFEKLL-----KRYPDSPKAPDAL 70

                         90
                 ....*....|....*.
gi 198041728 209 NNLAVLYGKRGKYKEA 224
Cdd:COG1729   71 LKLGLSYLELGDYDKA 86
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
165-316 6.91e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 38.36  E-value: 6.91e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 165 MLNILALVYRDQNKYKEAAHLLNDALAIREKtlgkdhpavaATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHP 244
Cdd:COG4785    1 LYALALALLLALALAAAAASKAAILLAALLF----------AAVLALAIALADLALALAAAALAAAALAAERIDRALALP 70

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 198041728 245 DVAKQLSNLALLCQNQGKAEEVEYYYRRALEIyatrlgpdDPNVAKTKNNLASCYLKQGKYQDAETLYKEIL 316
Cdd:COG4785   71 DLAQLYYERGVAYDSLGDYDLAIADFDQALEL--------DPDLAEAYNNRGLAYLLLGDYDAALEDFDRAL 134
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 131-321 7.86e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 38.38  E-value: 7.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 131 YASQGRYEVAVPLCKQALEdlektsghDHPDVATMLNILALVYRDQNKYKEAAHLLNDALAIR-----EKTL-------G 198
Cdd:cd24142   10 LLDQGNFELALKFLQRALE--------LEPNNVEALELLGEILLELGDVEEAREVLLRAIELDpdggyEKYLylgqlsgG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 199 KDhpAVAATLNNLAVLYGKRGKYKEAEPLCKRALEirekvlgkfhpDVAKQLSNlAL----------LCQNQGKAEEVEY 268
Cdd:cd24142   82 EE--ALQYYEKGIEILEEELQALQAASAEAEEEAE-----------ELKRKLSS-ALcalaeiymtdLCDEPDAEQRCEE 147

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 198041728 269 YYRRALEIYatrlgPDDPNVAKTknnLASCYLKQGKYQDAetlyKEILTRAHE 321
Cdd:cd24142  148 LITKALELD-----PTNPEALQT---LASLRISQQRPDEA----KEALRRSLE 188
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
169-320 8.63e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 37.94  E-value: 8.63e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 198041728 169 LALVYRDQNKYKEAAHLLNDALAirektlgKDHPAVAATLNNLAVLYGKRGKYKEAeplckraLEIREKVLGKfHPDVAK 248
Cdd:COG4700   95 LADALLELGRYDEAIELYEEALT-------GIFADDPHILLGLAQALFELGRYAEA-------LETLEKLIAK-NPDFKS 159

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 198041728 249 QLSNL--ALLCQNQGKAEEVEYYYRRALEIYATrlgpddpnvAKTKNNLASCYLKQGKYQDAETLYKEILTRAH 320
Cdd:COG4700  160 SDAHLlyARALEALGDLEAAEAELEALARRYSG---------PEARYRYAKFLARQGRTAEAKELLEEILDEAK 224
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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