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Conserved domains on  [gi|5441947|gb|AAD43192|]
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verified by mouse ESTs AA617614 (NID:g2504819) and AA237696 (NID:g1861718), partial [Homo sapiens]

Protein Classification

protein kinase family protein( domain architecture ID 229378)

protein kinase family protein may catalyze the transfer of the gamma-phosphoryl group from ATP to substrates such as serine/threonine and/or tyrosine residues on proteins, or may be a pseudokinase

CATH:  1.10.510.10
PubMed:  16244704
SCOP:  4003661

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PKc_like super family cl21453
Protein Kinases, catalytic domain; The protein kinase superfamily is mainly composed of the ...
 1-118 5.39e-43

Protein Kinases, catalytic domain; The protein kinase superfamily is mainly composed of the catalytic domains of serine/threonine-specific and tyrosine-specific protein kinases. It also includes RIO kinases, which are atypical serine protein kinases, aminoglycoside phosphotransferases, and choline kinases. These proteins catalyze the transfer of the gamma-phosphoryl group from ATP to hydroxyl groups in specific substrates such as serine, threonine, or tyrosine residues of proteins.


The actual alignment was detected with superfamily member cd13971:

Pssm-ID: 473864 [Multi-domain]  Cd Length: 298  Bit Score: 145.44  E-value: 5.39e-43
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5441947    1 IFVDNFVHADLHPGNILVQGANGLSSSQeaqlqqadicdtlVVAVPSSLCPLRLVLLDAGIVAELQAPDLRNFRAVFMAV 80
Cdd:cd13971 193 LFVDNFVHGDLHPGNILVRFNDSNRPSL-------------LVSLDARGSPPRLVFLDAGLVTELSPQDRRNFIDLFKAV 259

                        90       100       110
                ....*....|....*....|....*....|....*....
gi 5441947   81 VMGQGQRVAELILHHARAS-ECRDVEGFKTEMAMLVTQA 118
Cdd:cd13971 260 ARGDGYKAAELMLERSRSSqTCPDPEGFKSEMEELVNDA 298
 
Name Accession Description Interval E-value
ADCK2-like cd13971
aarF domain containing kinase 2 and similar proteins; This subfamily is composed of ...
 1-118 5.39e-43

aarF domain containing kinase 2 and similar proteins; This subfamily is composed of uncharacterized ABC1 kinase-like proteins including the human protein called aarF domain containing kinase 2 (ADCK2). Eukaryotes contain at least three ABC1-like proteins; in humans, these are ADCK3 and the putative protein kinases named ADCK1 and ADCK2. Yeast Abc1p and its human homolog ADCK3 are atypical protein kinases required for the biosynthesis of Coenzyme Q (ubiquinone or Q), which is an essential lipid component in respiratory electron and proton transport. In algae and higher plants, ABC1 kinases have proliferated to more than 15 subfamilies, most of which are located in plastids or mitochondria. Plant subfamily 10 (ABC1K10) belong to the same group of ABC1 kinases as human ADCK2. ABC1 kinases are not related to the ATP-binding cassette (ABC) membrane transporter family.


Pssm-ID: 270873 [Multi-domain]  Cd Length: 298  Bit Score: 145.44  E-value: 5.39e-43
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5441947    1 IFVDNFVHADLHPGNILVQGANGLSSSQeaqlqqadicdtlVVAVPSSLCPLRLVLLDAGIVAELQAPDLRNFRAVFMAV 80
Cdd:cd13971 193 LFVDNFVHGDLHPGNILVRFNDSNRPSL-------------LVSLDARGSPPRLVFLDAGLVTELSPQDRRNFIDLFKAV 259

                        90       100       110
                ....*....|....*....|....*....|....*....
gi 5441947   81 VMGQGQRVAELILHHARAS-ECRDVEGFKTEMAMLVTQA 118
Cdd:cd13971 260 ARGDGYKAAELMLERSRSSqTCPDPEGFKSEMEELVNDA 298
AarF COG0661
Predicted protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family [Coenzyme ...
 1-183 4.07e-25

Predicted protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family [Coenzyme transport and metabolism, Signal transduction mechanisms]; Predicted protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440425 [Multi-domain]  Cd Length: 487  Bit Score: 101.05  E-value: 4.07e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5441947    1 IFVDNFVHADLHPGNILVQgANGlsssqeaqlqqadicdtlvvavpsslcplRLVLLDAGIVAELQAPDLRNFRAVFMAV 80
Cdd:COG0661 275 VFRDGFFHADPHPGNIFVL-PDG-----------------------------RLVLLDFGMVGRLDPETREGLAELLLAL 324

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5441947   81 VMGQGQRVAELILHHARASECRDVEGFKTEMAMLVTQARknTITLEKLHVSSLLSSVFKLLMTHKVKLESNFASIVFAIM 160
Cdd:COG0661 325 LNRDYDRVAEALLELGFVPPDTDVDELERALRAVLEPYF--GKPLKDISFGELLLELFELARRFPLRLPPELVLLQRTLL 402

                       170       180
                ....*....|....*....|...
gi 5441947  161 VLEGLGRSLDPKLDILEAARPFL 183
Cdd:COG0661 403 TLEGVGRQLDPDFDLWEVAKPFL 425
UbiB TIGR01982
2-polyprenylphenol 6-hydroxylase; This model represents the enzyme (UbiB) which catalyzes the ...
 1-183 4.60e-19

2-polyprenylphenol 6-hydroxylase; This model represents the enzyme (UbiB) which catalyzes the first hydroxylation step in the ubiquinone biosynthetic pathway in bacteria. It is believed that the reaction is 2-polyprenylphenol -> 6-hydroxy-2-polyprenylphenol. This model finds hits primarily in the proteobacteria. The gene is also known as AarF in certain species. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273909  Cd Length: 437  Bit Score: 83.50  E-value: 4.60e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5441947      1 IFVDNFVHADLHPGNILVQGANglsssqeaqlqqadicdtlvvavpsslcplRLVLLDAGIVAELQAPDLRNFRAVFMAV 80
Cdd:TIGR01982 273 VLRDGFFHADLHPGNIFVLKDG------------------------------KIIALDFGIVGRLSEEDRRYLAEILYGF 322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5441947     81 VMGQGQRVAELILHHARASECRDVEGFKTEMAMLVTQARknTITLEKLHVSSLLSSVFKLLMTHKVKLESNFASIVFAIM 160
Cdd:TIGR01982 323 LNRDYRRVAEVHFDAGYVPSDTDMAEFEQAIRAIGEPIF--GQPLKEISVGRLLAGLFKITRDFNMELQPQLLLLQKTLL 400

                         170       180
                  ....*....|....*....|...
gi 5441947    161 VLEGLGRSLDPKLDILEAARPFL 183
Cdd:TIGR01982 401 TVEGVGRQLDPDLNMWKVAEPFV 423
ABC1 pfam03109
ABC1 atypical kinase-like domain; This family includes ABC1 from yeast and AarF from E. coli. ...
 1-91 1.39e-08

ABC1 atypical kinase-like domain; This family includes ABC1 from yeast and AarF from E. coli. These proteins have a nuclear or mitochondrial subcellular location in eukaryotes. The exact molecular functions of these proteins is not clear, however yeast ABC1 suppresses a cytochrome b mRNA translation defect and is essential for the electron transfer in the bc 1 complex and E. coli AarF is required for ubiquinone production. It has been suggested that members of the ABC1 family are novel chaperonins. These proteins are unrelated to the ABC transporter proteins.


Pssm-ID: 427143 [Multi-domain]  Cd Length: 245  Bit Score: 52.62  E-value: 1.39e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5441947      1 IFVDNFVHADLHPGNILVQGANglsssqeaqlqqadicdtlvvavpsslcplRLVLLDAGIVAELQAPDLRNFRAVFMAV 80
Cdd:pfam03109 184 IFRDGFFHADPHPGNILVRKDG------------------------------RIVLLDFGLMGRLDEKFRRLYAELLLAL 233

                          90
                  ....*....|.
gi 5441947     81 VMGQGQRVAEL 91
Cdd:pfam03109 234 VNRDYKRVAEM 244
ubiB PRK04750
putative ubiquinone biosynthesis protein UbiB; Reviewed
 1-183 8.72e-05

putative ubiquinone biosynthesis protein UbiB; Reviewed


Pssm-ID: 235310 [Multi-domain]  Cd Length: 537  Bit Score: 42.20  E-value: 8.72e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5441947     1 IFVDNFVHADLHPGNILVQGANGLSSsqeaqlqqadicdtlvvavpsslcplRLVLLDAGIVAELQAPDLRNFRAVFMAV 80
Cdd:PRK04750 276 VFRDGFFHADMHPGNIFVSYDPPENP--------------------------RYIALDFGIVGSLNKEDKRYLAENFLAF 329

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5441947    81 VMGQGQRVAELilhHARA----SECRdVEGFktEMAM-----------------------LVTQARKNTITLEKlhvssl 133
Cdd:PRK04750 330 FNRDYRRVAEL---HVESgwvpPDTR-VEEL--EFAIravcepifdkplaeisfghvllrLFNTARRFNVEIQP------ 397

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 5441947   134 lssvfKLLMTHKVKLEsnfasivfaimvLEGLGRSLDPKLDILEAARPFL 183
Cdd:PRK04750 398 -----QLVLLQKTLLN------------VEGLGRQLDPQLDLWKTAKPFL 430
 
Name Accession Description Interval E-value
ADCK2-like cd13971
aarF domain containing kinase 2 and similar proteins; This subfamily is composed of ...
 1-118 5.39e-43

aarF domain containing kinase 2 and similar proteins; This subfamily is composed of uncharacterized ABC1 kinase-like proteins including the human protein called aarF domain containing kinase 2 (ADCK2). Eukaryotes contain at least three ABC1-like proteins; in humans, these are ADCK3 and the putative protein kinases named ADCK1 and ADCK2. Yeast Abc1p and its human homolog ADCK3 are atypical protein kinases required for the biosynthesis of Coenzyme Q (ubiquinone or Q), which is an essential lipid component in respiratory electron and proton transport. In algae and higher plants, ABC1 kinases have proliferated to more than 15 subfamilies, most of which are located in plastids or mitochondria. Plant subfamily 10 (ABC1K10) belong to the same group of ABC1 kinases as human ADCK2. ABC1 kinases are not related to the ATP-binding cassette (ABC) membrane transporter family.


Pssm-ID: 270873 [Multi-domain]  Cd Length: 298  Bit Score: 145.44  E-value: 5.39e-43
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5441947    1 IFVDNFVHADLHPGNILVQGANGLSSSQeaqlqqadicdtlVVAVPSSLCPLRLVLLDAGIVAELQAPDLRNFRAVFMAV 80
Cdd:cd13971 193 LFVDNFVHGDLHPGNILVRFNDSNRPSL-------------LVSLDARGSPPRLVFLDAGLVTELSPQDRRNFIDLFKAV 259

                        90       100       110
                ....*....|....*....|....*....|....*....
gi 5441947   81 VMGQGQRVAELILHHARAS-ECRDVEGFKTEMAMLVTQA 118
Cdd:cd13971 260 ARGDGYKAAELMLERSRSSqTCPDPEGFKSEMEELVNDA 298
AarF COG0661
Predicted protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family [Coenzyme ...
 1-183 4.07e-25

Predicted protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family [Coenzyme transport and metabolism, Signal transduction mechanisms]; Predicted protein kinase regulating ubiquinone biosynthesis, AarF/ABC1/UbiB family is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440425 [Multi-domain]  Cd Length: 487  Bit Score: 101.05  E-value: 4.07e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5441947    1 IFVDNFVHADLHPGNILVQgANGlsssqeaqlqqadicdtlvvavpsslcplRLVLLDAGIVAELQAPDLRNFRAVFMAV 80
Cdd:COG0661 275 VFRDGFFHADPHPGNIFVL-PDG-----------------------------RLVLLDFGMVGRLDPETREGLAELLLAL 324

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5441947   81 VMGQGQRVAELILHHARASECRDVEGFKTEMAMLVTQARknTITLEKLHVSSLLSSVFKLLMTHKVKLESNFASIVFAIM 160
Cdd:COG0661 325 LNRDYDRVAEALLELGFVPPDTDVDELERALRAVLEPYF--GKPLKDISFGELLLELFELARRFPLRLPPELVLLQRTLL 402

                       170       180
                ....*....|....*....|...
gi 5441947  161 VLEGLGRSLDPKLDILEAARPFL 183
Cdd:COG0661 403 TLEGVGRQLDPDFDLWEVAKPFL 425
UbiB TIGR01982
2-polyprenylphenol 6-hydroxylase; This model represents the enzyme (UbiB) which catalyzes the ...
 1-183 4.60e-19

2-polyprenylphenol 6-hydroxylase; This model represents the enzyme (UbiB) which catalyzes the first hydroxylation step in the ubiquinone biosynthetic pathway in bacteria. It is believed that the reaction is 2-polyprenylphenol -> 6-hydroxy-2-polyprenylphenol. This model finds hits primarily in the proteobacteria. The gene is also known as AarF in certain species. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273909  Cd Length: 437  Bit Score: 83.50  E-value: 4.60e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5441947      1 IFVDNFVHADLHPGNILVQGANglsssqeaqlqqadicdtlvvavpsslcplRLVLLDAGIVAELQAPDLRNFRAVFMAV 80
Cdd:TIGR01982 273 VLRDGFFHADLHPGNIFVLKDG------------------------------KIIALDFGIVGRLSEEDRRYLAEILYGF 322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5441947     81 VMGQGQRVAELILHHARASECRDVEGFKTEMAMLVTQARknTITLEKLHVSSLLSSVFKLLMTHKVKLESNFASIVFAIM 160
Cdd:TIGR01982 323 LNRDYRRVAEVHFDAGYVPSDTDMAEFEQAIRAIGEPIF--GQPLKEISVGRLLAGLFKITRDFNMELQPQLLLLQKTLL 400

                         170       180
                  ....*....|....*....|...
gi 5441947    161 VLEGLGRSLDPKLDILEAARPFL 183
Cdd:TIGR01982 401 TVEGVGRQLDPDLNMWKVAEPFV 423
ABC1_ADCK3-like cd05121
Activator of bc1 complex (ABC1) kinases (also called aarF domain containing kinase 3) and ...
 1-92 2.17e-11

Activator of bc1 complex (ABC1) kinases (also called aarF domain containing kinase 3) and similar proteins; This family is composed of the atypical yeast protein kinase Abc1p, its human homolog ADCK3 (also called CABC1), and similar proteins. Abc1p (also called Coq8p) is required for the biosynthesis of Coenzyme Q (ubiquinone or Q), which is an essential lipid component in respiratory electron and proton transport. It is necessary for the formation of a multi-subunit Q-biosynthetic complex and may also function in the regulation of Q synthesis. Human ADCK3 is able to rescue defects in Q synthesis and the phosphorylation state of Coq proteins in yeast Abc1 (or Coq8) mutants. Mutations in ADCK3 cause progressive cerebellar ataxia and atrophy due to Q10 deficiency. Eukaryotes contain at least two more ABC1/ADCK3-like proteins: in humans, these are the putative atypical protein kinases named ADCK1 and ADCK2. In algae and higher plants, ABC1 kinases have proliferated to more than 15 subfamilies, most of which are located in plastids or mitochondria. Eight of these plant ABC1 kinase subfamilies (ABC1K1-8) are specific for photosynthetic organisms. ABC1 kinases are not related to the ATP-binding cassette (ABC) membrane transporter family.


Pssm-ID: 270691 [Multi-domain]  Cd Length: 247  Bit Score: 60.59  E-value: 2.17e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5441947    1 IFVDNFVHADLHPGNILVQgANGlsssqeaqlqqadicdtlvvavpsslcplRLVLLDAGIVAELQAPDLRNFRAVFMAV 80
Cdd:cd05121 186 IFEDGFFHADPHPGNILVL-PDG-----------------------------RIALLDFGMVGRLDPETREALADLLLAL 235

                        90
                ....*....|..
gi 5441947   81 VMGQGQRVAELI 92
Cdd:cd05121 236 VNGDAEGLAEAL 247
ABC1 pfam03109
ABC1 atypical kinase-like domain; This family includes ABC1 from yeast and AarF from E. coli. ...
 1-91 1.39e-08

ABC1 atypical kinase-like domain; This family includes ABC1 from yeast and AarF from E. coli. These proteins have a nuclear or mitochondrial subcellular location in eukaryotes. The exact molecular functions of these proteins is not clear, however yeast ABC1 suppresses a cytochrome b mRNA translation defect and is essential for the electron transfer in the bc 1 complex and E. coli AarF is required for ubiquinone production. It has been suggested that members of the ABC1 family are novel chaperonins. These proteins are unrelated to the ABC transporter proteins.


Pssm-ID: 427143 [Multi-domain]  Cd Length: 245  Bit Score: 52.62  E-value: 1.39e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5441947      1 IFVDNFVHADLHPGNILVQGANglsssqeaqlqqadicdtlvvavpsslcplRLVLLDAGIVAELQAPDLRNFRAVFMAV 80
Cdd:pfam03109 184 IFRDGFFHADPHPGNILVRKDG------------------------------RIVLLDFGLMGRLDEKFRRLYAELLLAL 233

                          90
                  ....*....|.
gi 5441947     81 VMGQGQRVAEL 91
Cdd:pfam03109 234 VNRDYKRVAEM 244
UbiB cd13972
Ubiquinone biosynthetic protein UbiB; UbiB is the prokaryotic homolog of yeast Abc1p and human ...
 2-91 1.51e-05

Ubiquinone biosynthetic protein UbiB; UbiB is the prokaryotic homolog of yeast Abc1p and human ADCK3 (aarF domain containing kinase 3). It is required for the biosynthesis of Coenzyme Q (ubiquinone or Q), which is an essential lipid component in respiratory electron and proton transport. It is required in the first monooxygenase step in Q biosynthesis. Mutant strains with disrupted ubiB genes lack Q and accumulate octaprenylphenol, a Q biosynthetic intermediate.


Pssm-ID: 270874 [Multi-domain]  Cd Length: 247  Bit Score: 44.11  E-value: 1.51e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5441947    2 FVDNFVHADLHPGNILVQgANGlsssqeaqlqqadicdtlvvavpsslcplRLVLLDAGIVAELQAPDlRNFRA-VFMAV 80
Cdd:cd13972 187 FRDGFFHADMHPGNIFVD-PNG-----------------------------RIIAVDFGIMGRLDKKD-RRYLAeILYGF 235

                        90
                ....*....|.
gi 5441947   81 VMGQGQRVAEL 91
Cdd:cd13972 236 LTRDYRRVAEL 246
ubiB PRK04750
putative ubiquinone biosynthesis protein UbiB; Reviewed
 1-183 8.72e-05

putative ubiquinone biosynthesis protein UbiB; Reviewed


Pssm-ID: 235310 [Multi-domain]  Cd Length: 537  Bit Score: 42.20  E-value: 8.72e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5441947     1 IFVDNFVHADLHPGNILVQGANGLSSsqeaqlqqadicdtlvvavpsslcplRLVLLDAGIVAELQAPDLRNFRAVFMAV 80
Cdd:PRK04750 276 VFRDGFFHADMHPGNIFVSYDPPENP--------------------------RYIALDFGIVGSLNKEDKRYLAENFLAF 329

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5441947    81 VMGQGQRVAELilhHARA----SECRdVEGFktEMAM-----------------------LVTQARKNTITLEKlhvssl 133
Cdd:PRK04750 330 FNRDYRRVAEL---HVESgwvpPDTR-VEEL--EFAIravcepifdkplaeisfghvllrLFNTARRFNVEIQP------ 397

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 5441947   134 lssvfKLLMTHKVKLEsnfasivfaimvLEGLGRSLDPKLDILEAARPFL 183
Cdd:PRK04750 398 -----QLVLLQKTLLN------------VEGLGRQLDPQLDLWKTAKPFL 430
ADCK1-like cd13969
aarF domain containing kinase 1 and similar proteins; This subfamily is composed of ...
 1-90 9.62e-05

aarF domain containing kinase 1 and similar proteins; This subfamily is composed of uncharacterized ABC1 kinase-like proteins including the human protein called aarF domain containing kinase 1 (ADCK1). Eukaryotes contain at least three ABC1-like proteins: in humans, these are ADCK3 and the putative protein kinases named ADCK1 and ADCK2. Yeast Abc1p and its human homolog ADCK3 are atypical protein kinases required for the biosynthesis of Coenzyme Q (ubiquinone or Q), which is an essential lipid component in respiratory electron and proton transport. In algae and higher plants, ABC1 kinases have proliferated to more than 15 subfamilies, most of which are located in plastids or mitochondria. Plant subfamilies 14 and 15 (ABC1K14-15) belong to the same group of ABC1 kinases as human ADCK1. ABC1 kinases are not related to the ATP-binding cassette (ABC) membrane transporter family.


Pssm-ID: 270871 [Multi-domain]  Cd Length: 253  Bit Score: 41.70  E-value: 9.62e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 5441947    1 IFVDNFVHADLHPGNILVQgANGLSSSQEaqlqqadicdtlvvavpsslcplrLVLLDAGIVAELqAPDLR-NFRAVFMA 79
Cdd:cd13969 183 IFVHGFVHCDPHPGNLLVR-KNPGPGKPQ------------------------IVLLDHGLYREL-DEEFRlNYCRLWKA 236

                        90
                ....*....|.
gi 5441947   80 VVMGQGQRVAE 90
Cdd:cd13969 237 LILGDEKKIKK 247
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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