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Conserved domains on  [gi|1397983621|pdb|6G18|M]
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Chain M, 40S ribosomal protein S12

Protein Classification

ribosomal L7Ae/L30e/S12e/Gadd45 family protein( domain architecture ID 10472466)

ribosomal L7Ae/L30e/S12e/Gadd45 family protein belongs to a family of K-turn-binding proteins that are important in ribosome structure, the site-specific modification of RNA, and spliceosome assembly

CATH:  3.30.1330.30
PubMed:  24149842

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ribosomal_L7Ae pfam01248
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from ...
 16-111 3.30e-30

Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118.


:

Pssm-ID: 426153 [Multi-domain]  Cd Length: 95  Bit Score: 104.21  E-value: 3.30e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6G18_M         16 TALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKId 95
Cdd:pfam01248   1 DAIYEVLKKALKTGKLVLGLKEVTKALERGEAKLVIIAEDCDPEEKVKLIPALCKEKNVPYVKVPSKKELGEACGKKRP- 79

                          90
                  ....*....|....*.
6G18_M         96 REGKPRKVVGCSCVVV 111
Cdd:pfam01248  80 VSALAIKDEGDSKILV 95
 
Name Accession Description Interval E-value
Ribosomal_L7Ae pfam01248
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from ...
 16-111 3.30e-30

Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118.


Pssm-ID: 426153 [Multi-domain]  Cd Length: 95  Bit Score: 104.21  E-value: 3.30e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6G18_M         16 TALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKId 95
Cdd:pfam01248   1 DAIYEVLKKALKTGKLVLGLKEVTKALERGEAKLVIIAEDCDPEEKVKLIPALCKEKNVPYVKVPSKKELGEACGKKRP- 79

                          90
                  ....*....|....*.
6G18_M         96 REGKPRKVVGCSCVVV 111
Cdd:pfam01248  80 VSALAIKDEGDSKILV 95
PTZ00222 PTZ00222
60S ribosomal protein L7a; Provisional
 34-120 1.42e-06

60S ribosomal protein L7a; Provisional


Pssm-ID: 140249  Cd Length: 263  Bit Score: 45.85  E-value: 1.42e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6G18_M        34 GIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGlckidregkpRKVVgcSCVVVKD 113
Cdd:PTZ00222 136 GLQEVTRAIEKKQARMVVIANNVDPVELVLWMPNLCRANKIPYAIVKDMARLGDAIG----------RKTA--TCVAITD 203


                 ....*..
6G18_M       114 YGKESQA 120
Cdd:PTZ00222 204 VNAEDEA 210
 
Name Accession Description Interval E-value
Ribosomal_L7Ae pfam01248
Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from ...
 16-111 3.30e-30

Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118.


Pssm-ID: 426153 [Multi-domain]  Cd Length: 95  Bit Score: 104.21  E-value: 3.30e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6G18_M         16 TALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKId 95
Cdd:pfam01248   1 DAIYEVLKKALKTGKLVLGLKEVTKALERGEAKLVIIAEDCDPEEKVKLIPALCKEKNVPYVKVPSKKELGEACGKKRP- 79

                          90
                  ....*....|....*.
6G18_M         96 REGKPRKVVGCSCVVV 111
Cdd:pfam01248  80 VSALAIKDEGDSKILV 95
PTZ00222 PTZ00222
60S ribosomal protein L7a; Provisional
 34-120 1.42e-06

60S ribosomal protein L7a; Provisional


Pssm-ID: 140249  Cd Length: 263  Bit Score: 45.85  E-value: 1.42e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
6G18_M        34 GIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGlckidregkpRKVVgcSCVVVKD 113
Cdd:PTZ00222 136 GLQEVTRAIEKKQARMVVIANNVDPVELVLWMPNLCRANKIPYAIVKDMARLGDAIG----------RKTA--TCVAITD 203


                 ....*..
6G18_M       114 YGKESQA 120
Cdd:PTZ00222 204 VNAEDEA 210
PRK13602 PRK13602
50S ribosomal protein L7ae-like protein;
34-95 9.39e-04

50S ribosomal protein L7ae-like protein;


Pssm-ID: 184174 [Multi-domain]  Cd Length: 82  Bit Score: 35.91  E-value: 9.39e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
6G18_M        34 GIREAAKALDKRQAHLCVLASNCDEPMYVKlVEALCAEHQINLIKVDDNKKLGEwvgLCKID 95
Cdd:PRK13602  15 GTKQTVKALKRGSVKEVVVAEDADPRLTEK-VEALANEKGVPVSKVDSMKKLGK---ACGIE 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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