Conserved Protein Domain Family
HMMR_C
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pfam15908: HMMR_C 
Hyaluronan mediated motility receptor C-terminal
HMMR_C is the C-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Links
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Statistics
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PSSM-Id: 464934
Aligned: 6 rows
Threshold Bit Score: 145.827
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_010717202 567 KKKSEVEKSRK-TIHEDmtSSLKEEIKTWRNLYEELHNKTKPFQQQLDAFEAEKNALLNEQGAAQEELNKLSEAYAKLLG 645
XP_007474038 565 NKQLVMEETRK-TREKN--MEFTEDVKKWRLLYEELYNKTKPFEQQLDAFEAEKRALLNEHGATQEELNKLSESYAKLLG 641
O75330       552 RKQLEDEEGRK-AEKENttAELTEEINKWRLLYEELYNKTKPFQLQLDAFEVEKQALLNEHGAAQEQLNKIRDSYAKLLG 630 human
2_pfamImport   1 QKLLEAEKQRKeAVDENtvIKLRAEAQKWQSLYEELSNKVKPFQEQLDAFEAEKNCLLNENGAAQEELNKLSDAYAKLLG 80 
NP_955874    754 HRQLAE------ARLQStsD---SETEHWRNLYEELYAKVKPFQEQLDRFAAERSALLNEKGATQAELNKLADAYANLMG 824
NP_001011731 681 TLQWEMEEQRQ--DLQRqvDQAQE--KRWEKVR--IY-HLFP-QEQLDAFAAERNALLSENGANQEELNKLSDAYARLLG 752 torafugu

XP_010717202 646 HQNQKQKIKHVMKLKEDNTHLQQDISKLRALLAKEKQTNKDLQEQLYTIQGIRRFDPSKAFQH--DSKENIPPKTPFKEG 723
XP_007474038 642 HQNQKQKIKHVMKLKEENNQLKLEVSKLRSQLAKEKQVGKKLQEQINEAKGFKRFDPSKAFQH--ESKENFSPKVPLKEG 719
O75330       631 HQNLKQKIKHVVKLKDENSQLKSEVSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHH--ESKENFALKTPLKEG 708 human
2_pfamImport  81 HQNQRQKIKHVVKLKEENSQLRQEVTKLRNQLAKEKQVQKKFEDQMKLAQGVRRFDT---FKH--DSKENDVPSTPLREG 155
NP_955874    825 HQNQRQKIKHMVKLKEENLELKQEVSKLRSQVGKQKQELDRLKSS----ETTRRFDPSKAFKH--ELKENQKPSSALTQG 898
NP_001011731 753 HQNQKQKIKHVMKLKDENTSLKQELSKLRSQVSRLKSDQEQLKSMLPGA-PRRRFDPSKAFQHnkENREN-EKNEPLREG 830 torafugu
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