1AUT,1KIG,5PA8


Conserved Protein Domain Family
FXa_inhibition

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pfam14670: FXa_inhibition 
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Coagulation Factor Xa inhibitory site
This short domain on coagulation enzyme factor Xa is found to be the target for a potent inhibitor of coagulation, TAK-442.
Statistics
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PSSM-Id: 464251
Aligned: 121 rows
Threshold Bit Score: 30.2886
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1AUT_L         57 CSLDNGG--CT--HYCL-EE-VGWRRCSCAPGYKLG--DDllQC 92   human
ESS28844       40 CSGNPCGgtAA--GTCI-NT-PSGYDCRCEPGYVLGveNDqvTC 79  
EEN59392      584 CQVNNGG--CQ--HTCV-GD-ARQHSCLCLPGHVLA--EDkhTC 619 
XP_002603386 1205 CQVDNGG--CQ--HTCV-GD-QSGYKCLCLPDYNLA--DDhrTC 1240
EDV26579      139 CRQSNGY--CQ--HLCV-DIsDEGHYCLCRKGYSLN--QDrrTC 175 
XP_004995058  247 CEDVPGR--CGenSLCV-YDgPDKFHCTCVEGYESAn-AEntDC 286 
XP_004990506  338 CMENEGI--CGdnATCEfAG-PGKYTCLCASGYEHD--SPtdKC 376  Salpingoeca rosetta
XP_004990506  382 CEQTPGP--CGdnSKCS-PTgPGTYTCLCEQGYESDd-SAqtNC 421  Salpingoeca rosetta
XP_002603386  474 CQVNNGG--CS--HTCV-GD-PNGHRCLCLSNFHLA--EDnhTC 509 
XP_002603387   46 CQENNGG--CQ--HTCV-GD-VSGHRCLCLPDYSLA--EDqhAC 81  
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