2DHG


Conserved Protein Domain Family
RRM2_SECp43
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cd12612: RRM2_SECp43 
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RNA recognition motif 2 (RRM2) found in tRNA selenocysteine-associated protein 1 (SECp43)
This subgroup corresponds to the RRM2 of SECp43, an RNA-binding protein associated specifically with eukaryotic selenocysteine tRNA [tRNA(Sec)]. It may play an adaptor role in the mechanism of selenocysteine insertion. SECp43 is located primarily in the nucleus and contains two N-terminal RNA recognition motifs (RRMs), also termed RBDs (RNA binding domains) or RNPs (ribonucleoprotein domains), and a C-terminal polar/acidic region.
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Statistics
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PSSM-Id: 410024
Aligned: 11 rows
Threshold Bit Score: 156.379
Created: 14-Dec-2011
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2DHG_A         9 EYSLFVGDLTPDVDDGMLYEFFvkvYPSCRGGKVVLDqTGVSKGYGFVKFTDELEQKRALTECQGavGLGSKPVRLSVAI 88  human
Q4KM14        98 EFSVFVGDLTSEVDDYQLHQFFlkkFPSCKGAKVVTDpYGNSRGYGFVKFSDENEQKKALEEFQNasGLGGKPIRISIAV 177 zebrafish
XP_002734331  98 EFSLFVGELSPEVDDYALYNFFsrrYPSIKGAKVIMDnAGMSRGFGFVRFGSEEEQQRALNEMQNasGLGGRSLRVSIAT 177 Saccoglossus ko...
XP_002125303  94 SFSIFVGDLDATVTDDKLEDFFlkrYRSVKGAKIMYEeGGISRGYGFVRFSDEAEQKRALQEMQGirGLGAKPIRVSVAT 173 Ciona intestinalis
Q503H1        93 TFSLFVSDLTPDVDDGMLYEFFhyhFSSCCSGKIVLDaNGHSKCCGFVSFESEREQKRALVDLQGatGLGKKALRLSLAS 172 zebrafish
NP_001238944  54 DYSIFVGELTPEVDDFQLYDYFlkrYPSCLDCKIATDlLGYSRGYAYVRFGEQGDQMRALQDCQNapGLGGKRIRLSIGI 133 chicken
EDV23390     131 EFSIFVGDLTPDVTDLVLRNFFcerFPSCKGAKVVIDqGGNSRGYGFVRFGDENEHTRALNEMQGasGCGGRPIRVSLAT 210 Trichoplax adha...
EEN65663      94 EYSIFVGDLTPEIDDGSLQEFFgrrYSSCKAAKVVLDaAGNSRGYGFVRFTDENEQKRALTEMQGavGLGGKALRVSPAT 173 Florida lancelet
KFW79647       2 EYSLFVGDLTPDVDDGMLYEFFvkvYPSCRGGKVVLDqAGVSKGYGFVKFTDELEQKRALTECQGavGLGSKPVRLSVAI 81  golden-collared...
XP_007893016  96 EYSLFVGDLTPEVDDGMLYEFFvekYPSCRGGKVVLDnLGNSRGYGFVKFSDENEQKRALGECQSaiGIGGKAIRLSVAI 175 elephant shark
XP_006005451 101 NFSLFIGNLTPEVDDGMLYEFFakmYPSCTGGKVVLDqLGNSKGYGFLRFSDEEEQKRAMTECHGaiGLGGKAIHLSVAI 180 coelacanth

2DHG_A        89 PK 90  human
Q4KM14       178 NK 179 zebrafish
XP_002734331 178 PK 179 Saccoglossus kowalevskii
XP_002125303 174 PK 175 Ciona intestinalis
Q503H1       173 SR 174 zebrafish
NP_001238944 134 SK 135 chicken
EDV23390     211 PK 212 Trichoplax adhaerens
EEN65663     174 PR 175 Florida lancelet
KFW79647      82 PK 83  golden-collared manakin
XP_007893016 176 PK 177 elephant shark
XP_006005451 181 PK 182 coelacanth
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