4II1,2CQE,5Z58


Conserved Protein Domain Family
zf_CCCH_4
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pfam18345: zf_CCCH_4 (this model, PSSM-Id:408151 is obsolete and has been replaced by 465719)
Zinc finger domain
This is a zinc finger domain found in Zinc finger CCCH-type with G patch domain-containing proteins such as ZIP. Functional studies indicate that ZIP specifically targets EGFR and represses its transcription, and that the zinc finger and the coiled-coil domains are central to that process.
Links
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Statistics
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PSSM-Id: 408151
Aligned: 291 rows
Threshold Bit Score: 23.1411
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4II1_A         79 CPFFLEGKCRFKENCRFSH 97  
A0CN12         85 CKYHAQNYCKNGSNCQYMH 103  Paramecium tetraurelia
XP_019078256  234 CQYFSQGWCVNGPNCKFMH 252  wine grape
XP_018669106  338 CQYYASGVCVHGDNCNYMH 356  vase tunicate
XP_008179059    7 CLYYISGSCRFGNNCWNLH 25   pea aphid
KIW69296        4 CKYFLQGNCRFGANCRNEH 22   Phialophora americana
CCF55553       84 CKYYKLGICKFGEECVNSH 102  Kazachstania africana CBS 2517
XP_012851978  114 CNLWAQGSCKFGDNCKYMH 132  spotted monkey flower
KEQ62221     1057 CKYFKKGQCQKGDTCTYRH 1075 Aureobasidium melanogenum CBS 110374
XP_001263035  934 CRYWREGKCLKGDNCTFRH 952  Aspergillus fischeri NRRL 181
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