Conserved Protein Domain Family
GAIN_A
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pfam18619: GAIN_A (this model, PSSM-Id:376045 is obsolete and has been replaced by 436625)
GPCR-Autoproteolysis-INducing (GAIN) subdomain A
GPR56 is a a cell-surface G protein-coupled receptor (GPCR) which belongs to the adhesion G protein-coupled receptor (aGPCR) family, a large family of chimeric proteins that have both adhesion and signaling functions and play critical roles in diverse neurobiological processes including brain development, synaptogenesis, and myelination. This entry represents GPCR-Autoproteolysis-INducing (GAIN) subdomain A, including PLL-GAIN linker (F161-D175) region.
Links
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Statistics
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PSSM-Id: 376045
Aligned: 14 rows
Threshold Bit Score: 85.9594
Created: 21-Apr-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q50DM6       173 SVDMCELKRDLQLLSQFLKHPQKASRRPSAAPARQQLQSLESKLTSVR 220 western lowland gorilla
XP_013221796 170 SWDMCDLKRDLGMLSRLLKQPLKSPRRPSLLPARQ-LQSLESKLAAVS 216 thirteen-lined ground squirrel
XP_023492825 170 SVDMCDLKRELQLLSQLLQHPQKMGRRPSLTPAHQRLQSLESKLASVR 217 horse
XP_020948992 175 SVDICELKRDLQLLSQLLKHPQKTSRRHQFIPASQRLQSLESKLTSVS 222 pig
EHB00663     173 SVDMCELKRDLQRLSQLLRKPRAGSRPP--LPASEQLQSLESKLSSVR 218 naked mole-rat
XP_010637182 173 SVDMCELKRDLQQLSQILRLPQKASRKSPATFASQQLQSLESKLSLVR 220 Damara mole-rat
XP_011358395 173 SVDMCELKRDLQLLSQLLKHPRKNSRKPSATAASHRLHSLESKLTSVR 220 large flying fox
XP_010594360 172 SVDICELKRDLELLSKLLKHPRKSSRRPSSTPARQHLQSLESKLTSMR 219 African savanna elephant
XP_017197735 173 SGDMCELKRDLQLLSQLLRHPQKAARRPSSSLAHRKLQSLESKLASVR 220 rabbit
XP_012396157 178 SVDMCDLKRELQSLSVLLSNPGKAGRKPASN--SKHLQNLESKLVGVH 223 Tasmanian devil
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