3TON


Conserved Protein Domain Family
NtCtMGAM_N
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pfam16863: NtCtMGAM_N (this model, PSSM-Id:374852 is obsolete and has been replaced by 465286)
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N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase
NtCtMGAM_N is a beta-barrel-like structure just N-terminal to the catalytic domain of maltase-glucoamylase in eukaryotes. It contributes to the architecture of the substrate-binding site, by donating a loop that comes into close contact with two regions in the catalytic domain thereby creating the site. This family is frequently found at the N-terminus of Glycosyl hydrolase 31, pfam01055.to which it contributes as above.
Links
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Statistics
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PSSM-Id: 374852
Aligned: 361 rows
Threshold Bit Score: 63.2906
Created: 23-May-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3TON_A          63 G-ATADISLKSSvYAN---AFPsT--PVNPLRLDVTYHKNEMLQFKIYDPNKNRYEVPVPLN----Ip----SMPSSTPE 128  human
EFV57874       110 GqATLTYDGE-----E---FYG-P--AVEPLAVNLSVVDDNIFRITIYDPNEKRFQIPDSLLrlpaGri--gK------- 169  Trichinella ...
65_pfamImport    1 G-FYQIIDKSKTaFE----PYG-T--EFDQLNVTVVRVSKFKLRIRIAPTIEKRFEVPWEHEave----------dvpDY 62  
EKC41762       146 G-PTKIYDRPV----------------YKEVDVSVDEYGDNALRIFFRPVNSSAFEIPDEALkinrPs---------pAT 199  Pacific oyster
EKC41761       142 G-PEEVYGMKV----------------HPEVDVTVEDYGDNALRIYFRPSNTQPFEIPEEALkinrPa---------pAT 195  Pacific oyster
XP_024659087   975 G-MTLDITRNRK-YRSsgrPQS-R--DIDTLRVEINYHTGEMLQFKIFDPNTKRYEVP---V----Gls-lpATPETDEN 1041 zebra mbuna
XP_018667949   159 G-LSQRIGKSKTaAS----PYG-E--EFDELLVTYTRVSNNKLRITIAPTSVKRFEIPWTHEsas----------ntpVQ 220  vase tunicate
XP_023817356   983 G-IRVDINRNTRyRSS---GRP-DspDIDSLRVEINYHTGDMLQFKIWDPSTERFEVPvp-----lTvpstpESD---ED 1049 Japanese medaka
XP_014351141   977 G-KRVQLTRNTAyPDR---YGS-HspSFDKLVLDIMYHNDYMLEFKIYVPNVPRYEVPvp-----lNipnnpAND---GS 1043 coelacanth
XP_016847510  1869 G-LTADLHRNTEfPNP---YGS-RspAVDLLRLEVTYHYNDMLQFKIYDPNNKRYEVPvp-----lFtpnnpEST---DA 1935 green anole

3TON_A         129 gqlYDVL-----IKKN--P-FGIEIRRKSTGTIIWDSQll-gFTFSDMFIRIST 173  human
EFV57874       170 ---LETDccrmeLCKN--P-FGVRLVRKSTGKTLFDSCntqdFYFADQFLQIST 217  Trichinella spiralis
65_pfamImport   63 atqYNVK-----YTTNdnGiFGIIVTRKSTGSVIFDTTvg-rLMFADQFLQLST 110 
EKC41762       200 nkkYKVE-----FVRE--PtFGIKVTRKSSNTVIFDSSlp-gLTFSDQFLQIST 245  Pacific oyster
EKC41761       196 nklYRVE-----VVKT--PtFGIKVIRNSTGSVVFDSSlp-gLTFSDQFLQIST 241  Pacific oyster
XP_024659087  1042 krlYKVV-----IVNE--P-FGIQVIRKSTGTVIWDSSvp-gFTFSDMFIQVST 1086 zebra mbuna
XP_018667949   221 dtlYDVQ-----FTSTn-GlFGIQVTRKSTNAILFDTTvg-rMMFSDQFLQIST 267  vase tunicate
XP_023817356  1050 krlYRVS-----VTES--P-FGIQVVRKSTGTTVWDSSmp-gFIFSNMFIQIST 1094 Japanese medaka
XP_014351141  1044 erlYEVK-----IMDK--P-FGIQIIRKSTGTIIWDSQlp-gFTFSDQFIQMST 1088 coelacanth
XP_016847510  1936 drlYQVE-----IVNN--P-FGIQIKRKSTGSVIWNSQvp-gFTFSDMFIQIAT 1980 green anole
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