Conserved Protein Domain Family
DUF4596
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pfam15363: DUF4596 (this model, PSSM-Id:373786 is obsolete and has been replaced by 464673)
Domain of unknown function (DUF4596)
This domain family is found in eukaryotes, and is approximately 50 amino acids in length. There is a conserved ELET sequence motif. There are two completely conserved residues (S and E) that may be functionally important.
Links
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Statistics
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PSSM-Id: 373786
Aligned: 12 rows
Threshold Bit Score: 51.7454
Created: 25-Apr-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_001507357 1321 DTfSSRRELMSPPDDPSTSLP-VTNFSSED-SySPQGEWTILELETQH 1366 platypus
EHB02585     1357 DTlNRWSELSSPLDNSSTSIT-MSSFSSED-C-SPQGEWTILELETQH 1401 naked mole-rat
EGW07960     1128 DSwNRWSELSSPLDGSWTSDT--TAGVPSE-GcSPLGEWTILELETQH 1172 Chinese hamster
D4A0X3       1193 DTwNRWSELSSPLDDLTASAT-TVSVSSTD-C-SPQGEWTILELETQH 1237 Norway rat
XP_015146171 1735 DTfSRWTELMSPLDDSSASIT-VASFSSED-CsSPQGEWTILELETHH 1780 chicken
XP_015817814 1472 ETfKRWAELISPMEDSSTSIT-VTSFSPED-AaSPQGEWTIVELETHH 1517 turquoise killifish
XP_006013649 1765 DTiSKWTELMSPLEDSTNSIT-VASFSPED-TtSTEGEWTIVELETHH 1810 coelacanth
XP_002933841 1581 ETsSRWGDIASPYDD-STSIT-VTSFSPDD-CsSPHGEWTILELETHH 1625 tropical clawed frog
EGW03402      224 aelGRWAELLSPLDESRASITsVTSFSPDD-VaSPQGDWTVVEVETFH 270  Chinese hamster
XP_015204437 1138 lesSRWPELLSPLDPPGASITaVTSYSPED-HgCSQGDWTVVELETHH 1184 spotted gar
XP_022539132 2027 lesSLWPHILPQLSPTSATITaVSSYSPTSqGsVPQGDWTVVELETHH 2074 Mexican tetra
XP_689188    1459 ES-SMWPNLLPPLTPPSATVTsVSSFSPEApGsSAQGEWTVVELETHH 1505 zebrafish
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