Conserved Protein Domain Family
DUF3719
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pfam12516: DUF3719 (this model, PSSM-Id:372160 is obsolete and has been replaced by 463617)
Protein of unknown function (DUF3719)
This domain family is found in eukaryotes, and is approximately 70 amino acids in length. There is a conserved HLR sequence motif. There are two completely conserved residues (W and H) that may be functionally important.
Links
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Statistics
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PSSM-Id: 372160
Aligned: 23 rows
Threshold Bit Score: 44.2781
Created: 1-May-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EGT53824      37 VFDGKELD--D---PELNQEAMLWRDKFPHIRVIGiscgeHKVTHPA------------AVSPVSPNTLKSAMNH 94  Caenorhabditis brenneri
Q6NSV7       117 LYEQQLSA--Ht--QGLQKECQQWAASFPHLRILG-----RQIITPSegygl--yprspSAVSASHEATLSQERE 180 house mouse
XP_012656876 114 LYEQKLSM--Ht--KILQEECQQWTASFPHLRILG-----RQIIAPSeddgf--yprspT-VSASYEAPLSQERD 176 small-eared galago
XP_002718468 115 LYERKLSV--Ht--KSLQEECQEWTASFPHLRILG-----RQIITPSedygl--yprcpSVLSASREATLPQERD 178 rabbit
EEN59063     120 LYEGRQKG--N---QQIYNECKEWVSMFPHLRICG-----AQLLEPQdqgf-----rhipSEGTARPSTGTVVTD 179 Florida lancelet
EDO26966      30 LFEGKGFN--Gs--SQLLLECQEWCTKFPHLRICG-----VQSVHPQdegtqyvplppdDPRVYNYRPQTSVLED 95  starlet sea anemone
XP_023351132 115 LYEQKSSI--Ht--KGLQEECQQWTSTFPHLRILG-----KQIVTSCegygl--yprspSVISASHETTLNQEKE 178 Tasmanian devil
XP_011482661 122 LYEGRGSGsgIl--PGLKEECQQWTMRFPHLRILG-----KQLLPPTdegfq--wyatpEGVTPADSPSTGKENS 187 Japanese medaka
XP_005005388   9 LYERKLSV--Ht--RSLHDECQQWTSSFPHLRILG-----RQIITPSegyel--yprspSAVSVSQEAVLSQERD 72  domestic guinea pig
XP_005474333 124 LYEGRGSG--GgilQGLQDECQQWATRFPHLRILG-----TQLLCPSdegfq--wyttsGKGSASSRPSAGKEsg 189 Nile tilapia
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