pfam08694: UFC1 (this model, PSSM-Id:370069 is obsolete and has been replaced by 400850)
Ubiquitin-fold modifier-conjugating enzyme 1
Ubiquitin-like (UBL) post-translational modifiers are covalently linked to most, if not all, target protein(s) through an enzymatic cascade analogous to ubiquitylation, consisting of E1 (activating), E2 (conjugating), and E3 (ligating) enzymes. Ubiquitin-fold modifier 1 (Ufm1) a ubiquitin-like protein is activated by a novel E1-like enzyme, Uba5, by forming a high-energy thioester bond. Activated Ufm1 is then transferred to its cognate E2-like enzyme, Ufc1, in a similar thioester linkage. This family represents the E2-like enzyme.
Jiyao W et al.(2023). "The conserved domain database in 2023.",