pfam07830: PP2C_C (this model, PSSM-Id:369544 is obsolete and has been replaced by 429684)
Protein serine/threonine phosphatase 2C, C-terminal domain
Protein phosphatase 2C (PP2C) is involved in regulating cellular responses to stress in various eukaryotes. It consists of two domains: an N-terminal catalytic domain and a C-terminal domain characteristic of mammalian PP2Cs. This domain consists of three antiparallel alpha helices, one of which packs against two corresponding alpha-helices of the N-terminal domain. The C-terminal domain does not seem to play a role in catalysis, but it may provide protein substrate specificity due to the cleft that is created between it and the catalytic domain.
Jiyao W et al.(2023). "The conserved domain database in 2023.",