Conserved Protein Domain Family
Drf_FH1
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pfam06346: Drf_FH1 (this model, PSSM-Id:368851 is obsolete and has been replaced by 461881)
Formin Homology Region 1
This region is found in some of the Diaphanous related formins (Drfs). It consists of low complexity repeats of around 12 residues.
Links
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Statistics
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PSSM-Id: 368851
Aligned: 8 rows
Threshold Bit Score: 40.5878
Created: 4-May-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EHA99368      571 PPPLPGvgsnlp---tcplpgNVCIPTPSSMPAGTGIPPPPPLPRSTSI----PSPPPLPGITYIPPPPPLPG------- 636  naked mole-rat
4_pfamImport    1 SPPLPG---------------GFGIPPPPPLPGGFGIPPPPPLPGGSGI----PPPPPLPGGSGIPPPPPLPG------- 54  
6_pfamImport    1 -------------------------PPPPPLPG-VGIPPPPPLPG-MGI----PPPPPLPG-VGIPPPPPLPG------- 41  
NP_001245364  574 APPLPGdss---------ggpGPVVPTSPPLLEGGSPVPAPLLPGGEAIppppPPPPPLPGAPCIPPPPPLPG------- 637  pig
NP_001292910  556 PPPLPGgvvpps----pplppGTCIPPPPPLPGGACIPPPPQLPGSAAI----PPPPPLPGVASIPPPPPLPG------- 620  house mouse
XP_004744819  619 PPPLPG---------------HAYIPPPPPLPGSVGSSVPPLLPGEAGI----PPPPPLPGGASIPPPPPLPG------- 672  domestic ferret
XP_005558107  573 APPLPGdsgtiirpppapgdstTPPPPPPPPPPPPPPPPPPPLIGSVCI----SSTPSLPGGTAIPPPPPLPE------- 641  crab-eating m...
XP_002807780  900 pPPLPG----------------VGIPPPPPLPG-TGIPPPPPLPG-VGI----PSPPPLPG-TGIPPPPPLPGvgipspp 956  white-tufted-...

EHA99368      637 ---STSIPPPPPLS------------GSTSIPPPPPLPGGAGI---PPPPPLPGGVGIpPPPPPLLGGPG-IPPPLPFPG 697  naked mole-rat
4_pfamImport   55 ---GSGIPPPPPLP------------GGSGIPPPPPFPGGPGI---PPPPPFPGGFGI-PPPPPFPGGPG-IPPPPPFPG 114 
6_pfamImport   42 -----GIPPPPPLP------------G-AGIPPPPPLPG-AGI---PPPPPLPG-AGI-PPPPPLPGAG--IPPPPPLPG 95  
NP_001245364  638 ---APCIPPPPPLP------------GVPDVPPPPPLPGVPGVpgvPPPPPLPGVPGVpPPPPPLPGGPGmLPPPPPLPG 702  pig
NP_001292910  621 ---ATAIPPPPPLP------------GATAIPPPPPLPGGTGIp--PPPPPLPGSVGV-PPPPPLPGGPGlppppppfPG 682  house mouse
XP_004744819  673 ---GASIPPPPPLPgatvispppplaGSTGIPPPPPLPGSAGIp--PPPPPLPGGAGMpPPPPPLPGGPG-IPPPPPIPG 746  domestic ferret
XP_005558107  642 ---GASIPPPPPLP------------GDVGIPPPPPLPGDAGIp--PPPPPLPGGAGMpPPPPPLPGGPG-IPPPPPFPG 703  crab-eating m...
XP_002807780  957 plpGTGIPPPPPLP------------G-TGIPPPPPLPG-VGI---PPPPPLPG-AGI-PPPPPLPGAV--IPPPPPLPG 1015 white-tufted-...

EHA99368      698 gpGIPPPPA---GMGM-----PPPPPF-GfGVPAAPVLP 727  naked mole-rat
4_pfamImport  115 gpGVPPPPPa-fGGGV-----PPPPGL-G-GWGAPPPLP 145 
6_pfamImport   96 a-GVPPPPPl-pGMGIppapaPPPPPL-GtGIPPPPLLP 131 
NP_001245364  703 --GLPPPPPfpgGPGI-----PPPLPV-GfGVPAAPVLP 733  pig
NP_001292910  683 apGIPPPPP---GMGV-----PPPPPF-GfGVPAAPVLP 712  house mouse
XP_004744819  747 gpGIPPPPP---GMGM-----PPPPPF-GfGVPAAPVLP 776  domestic ferret
XP_005558107  704 gpGIPPPPP---GMGM-----PPPPPF-GfGASAAPVLP 733  crab-eating macaque
XP_002807780 1016 v-GIPPPPPl-pGMGI-----PPPPPLpGvGIPPPPPLP 1047 white-tufted-ear marmoset
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