5Y31,5Y31,5Y31,5Y31,5Y31,5Y31


Conserved Protein Domain Family
EPTP
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pfam03736: EPTP (this model, PSSM-Id:367630 is obsolete and has been replaced by 461033)
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EPTP domain
Mutations in the LGI/Epitempin gene can result in a special form of epilepsy, autosomal dominant lateral temporal epilepsy. The Epitempin protein contains a large repeat in its C terminal section. The architecture and structural features of this repeat make it a likely member 7-bladed beta-propeller fold.
Links
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Statistics
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PSSM-Id: 367630
Aligned: 230 rows
Threshold Bit Score: 35.0836
Created: 19-Jun-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
5Y31_B       400 FTNQTDIPNMeDVYAVKHFSVKGDVYICLTRFIGDSKVMKW 440 human
Q28CE3       285 FRHYDSIKGV-SVVSCLPMVIGDQLFVVVAQLFGGSAVYRL 324 tropical clawed frog
XP_024852015 245 lRDYDRIPAP-SAVHCKPMVVDSQLYVVVAQLFGGSYIYHW 284 cattle
XP_005995299 214 FRKFENLSAQ-SAIYCKPLVVDDQLFVVVGQLFGGSHIYRW 253 coelacanth
XP_015197428 326 FRKFYNITSR-SAVYCKPVVIENTLYMVVAQLFGGSHIFKW 365 spotted gar
CAG12556     263 FRGFRNITSR-SAVYCKPALVDGGLHMIVAQLFGGSHIYRW 302 spotted green pufferfish
XP_002608998 243 FKVYNNITAP-SVVACTPVQMETDLFILAAQLYGGTRVFQF 282 Florida lancelet
XP_010793541 260 FRTYDNITGQ-SIVGCKSVVIQDQVFVIVAQLFGGSHIYKF 299 black rockcod
XP_022541676 255 FRPFDNITGR-SIIGCRSVLIGDHAFVIVAQLFAGTHIYKY 294 Mexican tetra
NP_001034731 266 FRPFDDITGR-SAVGCRSVLINEQAFVIVLQLFDGSLVYKY 305 zebrafish
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