Conserved Protein Domain Family
FDF
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pfam09532: FDF (this model, PSSM-Id:312888 is obsolete and has been replaced by 430668)
FDF domain
The FDF domain, so called because of the conserved FDF at its N termini, is an entirely alpha-helical domain with multiple exposed hydrophilic loops. It is found at the C-terminus of Scd6p-like SM domains. It is also found with other divergent Sm domains and in proteins such as Dcp3p and FLJ21128, where it is found N terminal to the YjeF-N domain, a novel Rossmann fold domain.
Links
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Statistics
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PSSM-Id: 312888
Aligned: 10 rows
Threshold Bit Score: 85.2031
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q9C658   460 KFTEDFDFTAMNEKFNKDEVWGHLGKSTTLDGde-------------------ddDSPTVDEAELPKIEAKPVYNKDDFF 520 thale cress
Q9FH77   426 EYTEEFDFEAMNEKFKKSELWGYLGRNNQRNQ-----------------------NDYGEETAIEPNAEGKPAYNKDDFF 482 thale cress
Q96F86   199 IPDTDFDFEGNLALFDKAAVFEEIDTYERRSGtrsrg--------------ipneRPTRYRHDENILESEPIVYRRIIVP 264 human
Q7RXT2   286 QEAGDFDFESGLAKFNKQDLFEQMRKDDLIDEadr------------------lvSHNRVPKHKPGTAGGKNLHHSENVL 347 Neurospora crassa
O94752    94 DCDEEFDFAANLEKFDKKQVFAEFREKDKKDPakl-----------------lvsHNKSPNRNYHHKQNVLGPSVKDEFV 156 Schizosaccharomyces...
Q9VTZ0   402 KFEGDFDFEQANNKFEELRSQLAKLKVAEDGApkpa---------------tnatAATATATNEQVGEKVEGVHTLNGET 466 fruit fly
Q7RX24   442 VPDSDFDFESSNAKFNKQEIVKEAIAGSPLGEepa------------------ieSAAPEAVADVSGVAQQAYNKSKSFF 503 Neurospora crassa
ELK00534 337 KFEKDFDFESANAQFNKEEIDREFHNKLKLKEdklekqekpvngedkgdsgvdtqNSEGNADEEDPLGPNCYYDKTKSFF 416 black flying fox
AJV38361 100 KQQEDFDFQRNLGMFNKKDVFAQLKQNDDILPenrlq--------------ghnrKQTQLQQNNYQNDELVIPDAKKDSW 165 Saccharomyces cerev...
KMK60888 411 VPDTDYDFESANAKFNKQDLVKEAIATGSPVTeagah-------------vengeVEAVDTAHHAPSTTASAYNKSASFF 477 Aspergillus fumigat...

Q9C658   521 DSLSSNTIDRESQNSRPR---------------------------------FSEQRKLDT-ETFGEF 553 thale cress
Q9FH77   483 DTISCNQLDRVARSGQQHn-------------------------------qFPEHMRQVP-EAFGNN 517 thale cress
Q96F86   265 HNVSKEFCTDSGLVVPSIsy-----------------------------elHKKLLSVA--EKHGLT 300 human
Q7RXT2   348 DMPSTILKPKLIVKETSNd-------------------------------fWNSEADDG--VINGAD 381 Neurospora crassa
O94752   157 DLPSAGSQINGIDAVLSSss-----------------------------ngHVTPGSKK--GSRETL 192 Schizosaccharomyces pombe 972h-
Q9VTZ0   467 DKKDDSGNETGAGEHEPEeddvavcydktksffdnisceaaqdrsknkkndWRQERKLNT-ETFGVS 532 fruit fly
Q7RX24   504 DNISSEAKDRAENNGQKPgg-----------------------------reWRGEEQRRNiETFGQG 541 Neurospora crassa
ELK00534 417 DNISCDDNRERRPT-------------------------------------WAEERRLNA-ETFGIP 445 black flying fox
AJV38361 166 NKISSRNEQSTHQSQPQQda-----------------------------qdDLVLEDDE--HEYDVD 201 Saccharomyces cerevisiae YJM689
KMK60888 478 DNISSEARDREERSGGRPgg-----------------------------reWRGEEEKRNiETFGQG 515 Aspergillus fumigatus Z5
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