Conserved Protein Domain Family
C8

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pfam08742: C8 (this model, PSSM-Id:312319 is obsolete and has been replaced by 462584)
C8 domain
This domain contains 8 conserved cysteine residues, but this family only contains 7 of them to overlaps with other domains. It is found in disease-related proteins including von Willebrand factor, Alpha tectorin, Zonadhesin and Mucin. It is often found on proteins containing pfam00094 and pfam01826.
Statistics
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PSSM-Id: 312319
Aligned: 928 rows
Threshold Bit Score: 26.1407
Created: 21-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9Y6R7         1877 FCGPLAPGtggPFTTCHAHVPPESFFKGCVLDVCM--GGGdRDILCKALASYVAACQaAGVVIe--D--WRAQVGC 1946 human
128_pfamImport    1 ECSVLKAa---TFAQCHPQVSPVRFFKSCLLDMCEc-PSG-KQCYCEALTAYAHECArHGVTQidpK--WREVTAC 69  
103_pfamImport    1 LCNRLKSq---IFDPCHKKVNPMMFFKACIQDMCEc-PT--QHCYCQSFMAYAHECKrLGIQLp--H--WRKATRC 66  
673_pfamImport    1 LCNRLRSs---IFESCHPKVNPAMYYKACLQDMCEc-PS--DHCYCESFMAYAHDCQrLGINLp--H--WRKSTRC 66  
26_pfamImport     1 NCNNIKQg---SFKLCHKAVEATPYFRSCMLDMCEclPS--DKCYCDSLNAYARECSrAGIQI---D--WKNSTNC 66  
86_pfamImport     1 RCKYLTKa--eFFGECESKLNYFKYYKTCKMDMCKcpSGR---CHCDSLLAYARECEkLGVQV---AagWRKESLC 68  
9_pfamImport      1 YCHPLSVSh--LFGECNERLNPQNYIAACRMDVCEc-PS--GSCHCDSFAAYAHECKrLGVILp--D--WRTATKC 67  
19_pfamImport     1 YCRPLRQSs--VFGKCDNRVSPDNYIESCRMDVCE--CPS-GNCHCDSFAAYAHECRrLGIKLp--D--WRTDTNC 67  
18_pfamImport     1 YCRPLRISe--VFGNCDSRLNPTNYIDSCRMDVCE--CPT-GSCHCDSFAAYAHECRrLGVQLp--D--WRTATNC 67  
811_pfamImport    1 FCKALRTAe--VFGNCNSLLNPDNYFESCKFDMCEc-PH--RQCYCDSMAAYAHECVrQGVQLp--D--WRTLTGC 67  
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