Conserved Protein Domain Family
Hepcidin
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pfam06446: Hepcidin (this model, PSSM-Id:310802 is obsolete and has been replaced by 461915)
Hepcidin
Hepcidin is a antibacterial and antifungal protein expressed in the liver and is also a signaling molecule in iron metabolism. The hepcidin protein is cysteine-rich and forms a distorted beta-sheet with an unusual disulphide bond found at the turn of the hairpin.
Links
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Statistics
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PSSM-Id: 310802
Aligned: 18 rows
Threshold Bit Score: 25.8167
Created: 20-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
P61516       43 QENQH-LTEAEHRQTdPLVL-----FRTKRQSHLSLCRFCCKCC-RNKGCGYCCKF 91  zebrafish
Q9EQ21       32 QTTELqPLHGEESRA-DIAIpm--qKRRKRDTNFPICIFCCKCC-NNSQCGICCKT 83  house mouse
Q99MH3       32 QTTALqPWHGAESKTdDSALlm--lKRRKRDTNFPICLFCCKCC-KNSSCGLCCIT 84  Norway rat
NP_001090729 31 TVTGNqIPETQMEESnALEPl----lRSKRQSHLSICVHCCNCC-KYKGCGKCCLT 81  western clawed frog
NP_001090730 31 KAPEHpISESEQGESdALGPl----FRTKR--HLNICVYCCKCCkKQKGCGMCCFT 80  western clawed frog
XP_002920925 32 QLAALqAQDAAGAEA-GLMPal--pRLRRRDTHFPICLFCCGCC-NKSKCGICCKT 83  giant panda
AAW82336     32 QLTDLrAQDTAGAEA-GLQPtlqlrRLRRRDTHFPICIFCCGCC-KTPKCGFCCKT 85  dog
NP_001103163 33 QLAELqPQDRAGARA-SWMPml--qRRRRRDTHFPICIFCCGCC-HRSKCGMCCKT 84  chimpanzee
CAG07920     37 VIDDDvAAAYEEISDdSWKTpy--tNRHKR--SPAGCRFCCGCCpRMRGCGVCCKF 88  spotted green pufferfish
XP_004085457 37 LTDDSpPAADQKIPVtSWKTly--dIRNKRDASAAGCRFCCGCC-GMSGCGVCCPF 89  Japanese medaka
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