P15066 1 METPFYGEEALSGLAAGASsvagatg--------apggggfAPPGRAFPGApp---tsSML------------KKdALTL 57 house mouse P27921 1 METPFYHDDVLSGLGSGFApts-----------------gsSGLLLPFPGG-------SMM------------KKdALGL 44 chicken P17535 1 METPFYGDEALSGLGGGASgsg----------------gsfASPGRLFPGApptaaagSMM------------KKdALTL 52 human P09450 5 MEQPFYHDDSYAAAGYGRS-----------------------PGSLSLHDY-------KLL------------KP-TLAL 41 house mouse XP_004910965 14 LEPPFYHEETLNLQEFAQMagysasgspgssgsggqqqgahREPGVRYQDH-------KLMganiiiqgsnlkKK-NMAT 85 western clawed ... XP_007259538 5 METTFY-DDSLSAAFSQHD-----------------------AAAFGY-NA-------KVL------------KH-SMTL 39 Mexican tetra XP_005795613 5 METTFY-DDSLNA-FSQND-----------------------NAGYGYGNP-------KAL------------KH-SMTL 39 southern platyfish XP_006635064 5 MEPTFY-DDSLNATFSQHE-----------------------TTGYGY-NP-------KAL------------KQ-NMTL 39 spotted gar NP_001185876 5 METTFY-DDALNASFLQTE-----------------------SGAYGYSNP-------KIL------------KQ-SMTL 40 rabbit XP_007480565 5 METTFY-DDALNAAFVQPE-----------------------SGGYGYSHA-------KVL------------KQ-SLTL 40 gray short-tail... XP_015726135 5 MEPTFY-EDALNASFAPPE-----------------------SGGYGYNNA-------KVL------------KQ-SMTL 40 Japanese quail XP_005458126 5 MEATFY-DEASN---SQHD----------------------GAAVYGF-NP-------KTL------------KQ-TMTL 37 Nile tilapia
P15066 58 SLAEQGAaGLK--------PGS-----------------------------------ATAPSalrpd-----gapdGLLA 89 house mouse P27921 45 ALPEQVAaALKa-------PGA-----------------------------------AAAAAaaagg-----eataGLLG 77 chicken P17535 53 SLSEQVAaALK--------PAA-----------------------------------APPPTplradgapsaappdGLLA 89 human P09450 42 NLADPYR-GLKgpgargpgPEG-----------------------------------SGAGSyf-------------sgQ 72 house mouse XP_004910965 86 VAPAVIQqGFP--------GEAlklmpgsgetavgnnpvpaageggagagavpsaaaGSTSN--------------SNSN 143 western clawed ... XP_007259538 40 NLTDPAG-TLK--------PHL-----------------------------------RAKAS--------------DLLT 61 Mexican tetra XP_005795613 40 NLSDPTC-SLK--------PHL-----------------------------------RAKAG--------------DLLT 61 southern platyfish XP_006635064 40 NLSDPTV-SLK--------PHL-----------------------------------RAKAN--------------DILT 61 spotted gar NP_001185876 41 NLADPVG-SLK--------PHL-----------------------------------RAKNS--------------DLLT 62 rabbit XP_007480565 41 NLADPVS-SLK--------PHL-----------------------------------RNKNP--------------DLLT 62 gray short-tail... XP_015726135 41 NLSDPAS-SLK--------PHL-----------------------------------RNKNA--------------DILT 62 Japanese quail XP_005458126 38 NLNDPK--NFK--------PHL-----------------------------------GAKAL--------------DILT 58 Nile tilapia
P15066 90 SPDLG-LL--------------KLASPELERLIIQ-SNG---------LVTTTPT-STQFLYPK----------V--AAS 131 house mouse P27921 78 SPEMG-ML--------------KLSSPELERLIIQ-SNG---------LVTTTPT-SGQFLYPK----------A--AAS 119 chicken P17535 90 SPDLG-LL--------------KLASPELERLIIQ-SNG---------LVTTTPT-SSQFLYPK----------V--AAS 131 human P09450 73 GSDTGaSL--------------KLASTELERLIVPnSNG---------VITTTPTpPGQYFYPRgggsgggtggG--VTE 127 house mouse XP_004910965 144 GADVP-LLpgtaaassaalsllKLSPPEIEHLLIQaANSgsapspassAQQPTIQ-IPPFLYRS----------QpvITQ 211 western clawed ... XP_007259538 62 SPDVG-LL--------------KLASPELERLIIQsSNG---------LITTTPT-PTQFLCPK----------N--VTD 104 Mexican tetra XP_005795613 62 SPDVG-LL--------------KLASPELERLIIQsSNG---------LITTTPT-PTQFLCPK----------N--VTD 104 southern platyfish XP_006635064 62 SPDVG-LL--------------KLASPELERLIIQsSNG---------LITTTPT-PTQFLCPK----------N--VTD 104 spotted gar NP_001185876 63 SPDVG-LL--------------KLASPELERLIIQsSNG---------HITTTPT-PTQFLCPK----------N--VTD 105 rabbit XP_007480565 63 SPDVG-LL--------------KLASPELERLIIQsSNG---------LITTTPT-PTQFLCPK----------N--VTD 105 gray short-tail... XP_015726135 63 SPDVG-LL--------------KLASPELERLIIQsSNG---------LITTTPT-PTQFLCPK----------N--VTD 105 Japanese quail XP_005458126 59 SPDVG-LL--------------KLASPELERLIIQsCNG---------L--TTPT-PTQFICPK----------N--ITD 99 Nile tilapia
P15066 132 EEQEFAEGFVKALEDLHKQSQl-GAATAATSGAPAPP----------APADL-----------AATP--------GATET 181 house mouse P27921 120 EEQEFAEGFVKALEDLHKQNQl-GGGGGPNGGAAAAGgggg--ggggGGGEL-----------PAPG--------LAPEP 177 chicken P17535 132 EEQEFAEGFVKALEDLHKQNQl-GAGAAAAAAAAAAGgpsgtatgsaPPGEL-----------APAA--------AAPEA 191 human P09450 128 EQEGFADGFVKALDDLHKMNH-----VTPPNVSLGASggp-----qaGPGGV-----------YAGP----------EPP 176 house mouse XP_004910965 212 EQEGFADGFVKALADLHKQNQl--LGAPISPTALAA-----------GSPSY-----------PVARtl-----lPAGEV 262 western clawed ... XP_007259538 105 EQEGFAEGFVRALAELHHQHM---PGTSAPPQTSTTVnss----maaAPAAA-----------AYSSa------pPRADP 160 Mexican tetra XP_005795613 105 EQEGFAEGFVRALAELHHQHM---PATTNASAPQASVnt------alPPVSS-----------VAGAtvynntpaMRSDS 164 southern platyfish XP_006635064 105 EQEGFAEGFVRALAELHHQNMpgVPSVTSAPQSNINNa--------mAPVSS-----------MAGNavf--nssMRSDP 163 spotted gar NP_001185876 106 EQEGFAEGFVRALAELHSQNT--LPSVT--SAAQPVSgag-----mvAPAVAsvagggggsggFSAG--------LHSEP 168 rabbit XP_007480565 106 EQEGFAEGFVRALAELHSQNT--LPGVPSAAAAQPGNasva--agmvAPPVA-----------AAGGfg-----gLHSEP 165 gray short-tail... XP_015726135 106 EQEGFAEGFVRALAELHNQNT--LPSVT--SAAQPVSgg-------mAPVSS-----------MAGGgsf--ntsLHSEP 161 Japanese quail XP_005458126 100 EQEGFAEGFVRALAELHYQQQ--IPAAQPDPQTGSANgm------tsGSAAP-----------ESGGisy--sctVRTEP 158 Nile tilapia
P15066 182 PVYANLSSFAGgagpp--------------ggaatVAFAAEPVPFPpppgalgp-------pppphppRLAALK---DEP 237 house mouse P27921 178 PVYANLSTYPA------------------------VSYAAEPGPFAapppr-------------lpppPPPPLK---DEP 217 chicken P17535 192 PVYANLSSYAGgagga--------------ggaatVAFAAEPVPFPpppppg-----------algppRLAALK---DEP 243 human P09450 177 PVYTNLSSYSPasapsggsgta--vgtgssyptatISYLPHAPPFAgghpaql-----------glsrgaSAFK---EEP 240 house mouse XP_004910965 263 PVYTNLSSFNPanaqlsppi-------pqapqptpYSGNPSPGAVQlqfp---------------glgRLHAGRgplDEP 320 western clawed ... XP_007259538 161 PVYADLSTFNPaisssaapgf------pavsytttapQPLAPPPQQqqapqp----------lpvqhpRLQALK---EEP 221 Mexican tetra XP_005795613 165 PVYEDLNTFNPaistvsap--------syttsapaVSFPAPPPQLPiygqps-----------paqlpRLTALK---EEP 222 southern platyfish XP_006635064 164 PVYADLSTFNPtmstaaap--------sysnantnMSYP--PPPHQhpmnsq----------lpvqhpRLQALK---EEP 220 spotted gar NP_001185876 169 PVYANLSNFNPsalssggg--------apsygaagLAFPAQPQ-QQqpppppqpphh-lpqqipvqhpRLQALK---EEP 235 rabbit XP_007480565 166 PVYANLSNFNPssalgsapayngaaggagaggggsLGFPQQPAAPQqqaqptnpqpplgpqlpgvqhpRLQALK---EEP 242 gray short-tail... XP_015726135 162 PVYANLSNFNPnalnsap-----------nynangMGYA-----PQhhinpq----------mpvqhpRLQALK---EEP 212 Japanese quail XP_005458126 159 PEYTNLSSFTRavtgstpap------agerqppppTSYPAAPQPSHnhmdhql--------pvaaqhpRLHALK---EEP 221 Nile tilapia
P15066 238 QTVPDVPSFGDSPP 251 house mouse P27921 218 QIVPEVPSFGESPP 231 chicken P17535 244 QTVPDVPSFGESPP 257 human P09450 241 QTVPEARSRDATPP 254 house mouse XP_004910965 321 QTVPDVSQAGAAPs 334 western clawed frog XP_007259538 222 QTVPEMP--GETPP 233 Mexican tetra XP_005795613 223 QTVPEMP--GETPP 234 southern platyfish XP_006635064 221 QTVPEMP--GETPP 232 spotted gar NP_001185876 236 QTVPEMP--GETPP 247 rabbit XP_007480565 243 QTVPEMP--GETPP 254 gray short-tailed opossum XP_015726135 213 QTVPEMP--GETPP 224 Japanese quail XP_005458126 222 QTVPEMS--GETPP 233 Nile tilapia
Jiyao W et al.(2023). "The conserved domain database in 2023.",