4LNB,4LNB,4LNB


Conserved Protein Domain Family
PPTA
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pfam01239: PPTA (this model, PSSM-Id:307411 is obsolete and has been replaced by 460128)
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Protein prenyltransferase alpha subunit repeat
Both farnesyltransferase (FT) and geranylgeranyltransferase 1 (GGT1) recognize a CaaX motif on their substrates where 'a' stands for preferably aliphatic residues, whereas GGT2 recognizes a completely different motif. Important substrates for FT include, amongst others, many members of the Ras superfamily. GGT1 substrates include some of the other small GTPases and GGT2 substrates include the Rab family.
Links
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Statistics
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PSSM-Id: 307411
Aligned: 844 rows
Threshold Bit Score: 24.65
Created: 13-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4LNB_A         244 ELQYSQSRILEAPENRSPWSYARGVLQA 271 Aspergillus fumigatus Af293
89_pfamImport    1 ELLRTEKFMRKHISDYSCYHYRQVLLGR 28 
762_pfamImport   1 ELNYTTQLLTKDFSNGSAWHYRSTLLAK 28 
4_pfamImport     1 ELHFTCLTLEENFSNYSAWHYRSGLIG- 27 
607_pfamImport   1 ELDYTTSVLKDNFSNFSAFHYRTTLIPR 28 
147_pfamImport   1 DLKFITDSINNNFSNYSAWHHRSVIFSS 28 
411_pfamImport   1 ELKFVTENINKNISNYSAWHQRTVLIPR 28 
177_pfamImport   1 EFEYTTKKIHEDLSNFSAWHNRSQIIAR 28 
269_pfamImport   1 EFSYTTRIIHRDLSNFSAWHNRSQLISR 28 
179_pfamImport   1 EFAYTERMISAGLSNFSAWHHRSRVIPR 28
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