2YYO


Conserved Protein Domain Family
SPRYD3
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cd12908: SPRYD3 
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SPRY domain-containing protein 3
This family contains SPRY domain-containing protein 3 (SPRYD3). In humans, it is highly expressed in most tissues, including brain, kidney, heart, intestine, skeletal muscle, and testis. It also has cross-species conservation, suggesting that it is likely to carry out important cellular processes.
Links
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Statistics
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PSSM-Id: 293965
Aligned: 18 rows
Threshold Bit Score: 239.507
Created: 29-Jun-2012
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2YYO_A         5 SSGFKh---ILVDGDt--LSYHGns---gEVGCYVASRPLtkDSNYFEVSIVDSGvrgTIAVGLVPQYYslDHQPGWLPD 76  human
EEN49312      54 RERYEr---VQLDGDm--LSYHPde--awRVGVFVSSQPItpDRNYFEVDIIDSGllsTIAIGLVPLNYrlDHQPGWGVD 126 Florida lancelet
AAI51932      29 QERYKr---MLKNGDt--LSYQGns---dEVGCYVAPRPLskGNCYFEVTIMDTGvrgTIAVGLVPQYYklDYQPGWLPQ 100 zebrafish
XP_003643504  28 QERAKh---VLVDGDt--LSYHGds---gEVGCYVAPRPLtrDNNYFEVSIVDSGvrgAIAVGLVPQHYslEHPPGWLPG 99  chicken
AAI29522      29 QERTKh---IAVDGDt--LSYHGns---gEVGCYVAPRPLskDNHYFEVSIVDRGvrgTIAVGLVPQYYslDHQPGWLPD 100 African clawed ...
XP_003385534  10 KGRHVcgrnAEVDGDi--FKYKGpa--anLVGVVKIAEPMspMFNYFEYEIIDKGqdtAIGIGLGEYKYplDRMPGWNRS 85  Amphimedon quee...
XP_002130328   8 KFRSAr---IDVTNDv--LSYDGgq--sqKVGCFLMSLPLneEMEYFELEILSTGvsgRITIGLAPYDYplDCQPGWKYG 80  Ciona intestinalis
XP_003385534 195 WLRSNg---IRYVDDgltLEYDGdglnrqDVGIAQALFPLssMNHYFELEILDSGqngWIAIGLGKSTYslTKHPGWCEG 271 Amphimedon quee...
XP_003385752 195 WLRSNg---VKFVDDglsLEYAGeggnvqDVGSAQANFQIspTNHYFELEIVDAGsigAVAIGLAKTTYplNRHPGWNPG 271 Amphimedon quee...
EKC35020     219 WSRLYd---VKLNGTm--LEYSGrgksihDVGLAQARYALdtSNHYFEIEIVDPGencYIAIGIARRNYpkNRHPGWNKG 293 Pacific oyster

2YYO_A        77 SVAYHADDGKLYngrAKGRQFGSKCnsGDRIGCGIEPvsfd--------------------------------------- 117 human
EEN49312     127 SVGYHADDGKLYkanGQGRAFGPKGfvGDRLGCGVKFeeegth------------------------------------- 169 Florida lancelet
AAI51932     101 SIAYHADDGKLYngnPVGQQFGPKCnrGDRIGCGIYAdsfd--------------------------------------- 141 zebrafish
XP_003643504 100 SVAYHADDGKLYsgrAKGRQFGTKCssGDRIGCGIERvsfe--------------------------------------- 140 chicken
AAI29522     101 SVAYHADDGKLYsgrTKGRQFGTKCssGDKIGCGIEPssfh--------------------------------------- 141 African clawed ...
XP_003385534  86 AIGYHADDGRLFhesGYGEAFGPLCtqGDRMGCGIHFdpdl--------------------------------------- 126 Amphimedon quee...
XP_002130328  81 SVAYHADDGRLFkctGAGTPFGPRCkvGDRMGCGVRAveqddgfnhd--------------------------------- 127 Ciona intestinalis
XP_003385534 272 SVGYHADNGHLYkekGQGDPFGPLCsaGDIMGCGVRFnegiitttfseidsdreeeeeeeepidsnfmfemgedddyyde 351 Amphimedon quee...
XP_003385752 272 AVGYHADDGKLFkekGMGSVFGPSCttGDTMGCGVRFtpssdyeeymeendsssetslpeevqyadqylsdnsdddyd-- 349 Amphimedon quee...
EKC35020     294 SVAYHADDGKIFvgsGVGEQFGPRChkGDIMGCGILFpndydseadsdqspddpdvsnreld------------------ 355 Pacific oyster

2YYO_A       118 -----------------------------------------------vqtAQIFFTKNGKRVGSTIxpxs--pdgLFPAV 148 human
EEN49312     170 --------------------------------------------grpastVSVFFTHNGKELGTVQvplp--pegLFPAV 203 Florida lancelet
AAI51932     142 -----------------------------------------------aglVTVFFTKNGKEVGSVVvpva--pdgLFPAI 172 zebrafish
XP_003643504 141 -----------------------------------------------vqtAQVFFTKNGKRVGCSAmpls--pegLFPAV 171 chicken
AAI29522     142 -----------------------------------------------vqtAQIFFTKNGKRVGSTVmpls--pdgLFPAV 172 African clawed ...
XP_003385534 127 ----------------------------------------------dsgyVYVFFTKNGSQIKEPVkmkr-plygFYPLV 159 Amphimedon quee...
XP_002130328 128 -----------------------------------------llmalpitsVEVYFTRNGEEVGTTTmllsengggLHPAV 166 Ciona intestinalis
XP_003385534 352 fdidpsflggfeagfrrrilprlnpgykkqlsgaaksgrdkdggvsekrtCTVYFTRNGELVGETEctip--nggFYPLV 429 Amphimedon quee...
XP_003385752 350 ---------dyfgfgglggglggrgfglrmpmqvpseskekkkdkdkertITVYFTKNGEEVGETEcvvp--sggFYPIV 418 Amphimedon quee...
EKC35020     356 -------------------------eypsdsdsedenmwwrqgndeqgtkVQVFFTRNGKIVGTKQvsip--kggFFPTV 408 Pacific oyster

2YYO_A       149 GXHSlGEEVRLHLN 162 human
EEN49312     204 GMHSeGEVVRLLLE 217 Florida lancelet
AAI51932     173 GMHSlGEEVRLDLQ 186 zebrafish
XP_003643504 172 GLHSlGEEVRLHLR 185 chicken
AAI29522     173 GMHSlGEEVRLHLN 186 African clawed frog
XP_003385534 160 GLHSvGEKVRYLGH 173 Amphimedon queenslandica
XP_002130328 167 GMHSgGESVKLCVL 180 Ciona intestinalis
XP_003385534 430 AMLSeGERIRVNFC 443 Amphimedon queenslandica
XP_003385752 419 AMLSrGEKIKVNLS 432 Amphimedon queenslandica
EKC35020     409 GMLSsCEKVRVDLH 422 Pacific oyster
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