Conserved Protein Domain Family
NCOA_u2
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pfam16665: NCOA_u2 (this model, PSSM-Id:293270 is obsolete and has been replaced by 465223)
Unstructured region on nuclear receptor coactivator protein
NCOA_u2 is a region of natively unstructured but highly conserved sequence found on higher eukaryote nuclear receptor coactivator proteins. It lies between a PAS domain, pfam14598 and a steroid receptor coactivator domain, pfam08832. The function is not known.
Links
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Statistics
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PSSM-Id: 293270
Aligned: 23 rows
Threshold Bit Score: 70.9781
Created: 24-Jul-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
Download Cn3D
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
NP_001012900  462 HNLNLSSSPMNSPGITPPQ---FMSPRHRVSPGLVPRPRGPSNPFSPTMpTMHSPVGM---AN--S-----GGGGngggg 528  chicken
XP_005992087  457 YGLSMSSPPHGSPGLNSAQqnlMVSPRSR------GSPKMNASQFSPAA-GIHSPMGP---TS--S-----T-GS----- 513  coelacanth
XP_012395281  468 HSLSLNNSPMDSTGITLAQ---FMSPRRQVSSGLATRPRMPSNSFSPNIpSLSSPIGM---VGsaC-----GNPN----- 531  Tasmanian devil
XP_010720816  462 YGLNISSPPHGSPGLTSNQqnlMISTRNR------GSPKMNSHQFSPVT-GMHSPMGS---AS--N-----TSNS----- 519  turkey
XP_003225969  467 HAMNLSSSPMNSPGVTPPQ---FMSPRHRVSPGLVHRPRVPSNPFSPTMpTTHSPVGM---MG--GcgvasAVGN----- 533  green anole
XP_010590070  460 YGLNMNSPPHGSPGLGSNQqniMISPRNR------GSPKMASHQFSPVP-GVHSPMGS---SG--N-----T-GS----- 516  African savan...
XP_009182062  467 pSLNLNNSPMEGTGISLAQ---FMSPRRQVTSGLTTRPRMPNNSFPPNIsTLSSPVGMtssAC--N-----NNTN----- 531  olive baboon
ETE70487      396 YGLNISSPPHGSPNLNASQpniMISPRNR------GSPKVNSHQFSPIP-GVHSPMGP---VS--N-----SSSN----- 453  king cobra
XP_007669569  476 ygLNMSSPPHGSPGLSSSQpniMISPRNR------GSPKMAPHQFSPVA-GLHSPMGS---AP--N-----A-GG----- 532  platypus
CAJ81360      458 YGLNMNSPPHGSPGMNSNQpnlMVSPRNRA------SPKMASNQFSPVP-GMNSPMGS---SG--S-----AGGG----- 515  western clawe...

NP_001012900  529 gggsRSFPTAPINSLQGLSEGASTPVGYSTPPPVLRQLGSQsS-PGRLGMQPMKAE-SKDSKEIAS 592  chicken
XP_005992087  514 ----NTFCNSSLNALQAISEGVGTSLLSTLSSPGQKMENSP-N----MNLPQQSKIsSQDCKSPSG 570  coelacanth
XP_012395281  532 ----RTYSNIPATSLQGINEGPSNSIGFSATSPVLRQLSSQ-NsPSRMNMLPTKAE-SKDSKEITS 591  Tasmanian devil
XP_010720816  520 ----TF-SSSSLSALQAISEGVGTSLLSTLSSPGPKLDSSP-N----VSIAQQNKAnNQDSKSPSG 575  turkey
XP_003225969  534 ----RPYPGTPLNSMQGLREGPSPPVGYSTPSPVLRQLSNQ-NsPSRMSMPPMKTE-PKDSKEMGS 593  green anole
XP_010590070  517 ----HSFSSSSLSALQAISEGVGTSLLSTLSSPGPKLDNSP-N----MNITQPSKVnSQDSKSPLG 573  African savanna elephant
XP_009182062  532 ----RSYSNIPVTSLQGMNEGPNNSVGFSANSPVLRQMSSQ-NsPSRLNIQPAKAE-SKDNKEIAS 591  olive baboon
ETE70487      454 ----NF-SSSSLSALQAISEGVGTTLLSTLSSPGPKLDSSP-N----MNAPPQSKMgSQDSKSPPG 509  king cobra
XP_007669569  533 ----PSFSSSSLSALQAISEGVGTSLLSTLSSPGPKLDHSP-N----VPPAQPAKTgGQESKSPPG 589  platypus
CAJ81360      516 ----SF-SSSSLSALHAISEGVGSSLLSSLSSPGQKVENNT-N----MNMPQQGKIgNQDCKSPSG 571  western clawed frog
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