Conserved Protein Domain Family
BCAS3
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pfam12490: BCAS3 (this model, PSSM-Id:289273 is obsolete and has been replaced by 463605)
Breast carcinoma amplified sequence 3
This domain family is found in eukaryotes, and is typically between 229 and 245 amino acids in length. The proteins in this family have been shown to be proto-oncogenes implicated in the development of breast cancer.
Links
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Statistics
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PSSM-Id: 289273
Aligned: 37 rows
Threshold Bit Score: 175.941
Created: 28-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q8GUL1       513 TAVALSVVSRIKYSSFGWLNTVSNATTAATGKVF------VPSGA-----VAAVFHKSVTHdLQ-LNsrT-N------AL 573  thale cress
XP_009402870 520 TPLTLSAVSRIRNGSNGLKGAVSGAAAAATGKVS------PLYGA-----IASAFHNCKGSgLQ-IDisSvR------TQ 581  wild Malaysian...
BAJ99624     553 PPVALSVVSRIRNGSNLLKGAVHGAAAFATGVSS------PISGA-----IASTFHNCKGGs--nSDgsFlC------MK 613  domesticated b...
XP_004244157 530 SPVTLSAVGRIRSGGNGWKNTLSGAAAAATGNVS------SLSGS-----IASAFQYYNKNhNQyTDpaFlK------LN 592  tomato
XP_010232446 518 PAVTLSVVSRIRNGSNLLKGAVHGAAAFATGVSS------PISGA-----IASTFHNCKGg-VPnSDgsLlC------MK 579  Brachypodium d...
BAD53258     401 PPVTLSVVSRIRNGGNLLKGAVHGAAAFATGVSS------PISGA-----IASTFHNCKGA-VKnSDgsSpC------MK 462  Japanese rice
XP_004970215 514 PPLTLSVVSRIRNGSNLFKGAVHGAAAFATGASS------PISGA-----IASTFHNCKDAdL---NsdSsR------TK 573  foxtail millet
ERM99845     450 SPITLSAVSRIRNGNNGWRATVNGAAAAATGRVNn-----ALSGA-----IASSFHDCNSGsYL-----DsR------IK 508  Amborella tric...
XP_006363524 475 PPVTLSAVGRIRSGGNGWRNTVTGAAAAATGRTI------SFSGS-----IASAFHHCNSTr-QcADsgLlK------AN 536  potato
XP_011670337 328 QTVTILPLEQIKLSTT--LGAVATSMAASTAKPGrgkaptQSSGAseysgLATCFALSRGHvQGaNQvpReKdstrvsPI 405  purple sea urchin

Q8GUL1       574 EHILVYTPSGHVVQHELLPSVCTeSpenglrvqktS--HVQVQEDDLRVKVEPIQWWDVCRRSDWLETEERlpksitekq 651  thale cress
XP_009402870 582 YYLLVFAPSGCIIQYVLRQWIGEnYgisvsgssnaS--YQSIQEADGRLDVEALQKWDVCHKRNRRDRSD---------- 649  wild Malaysian...
BAJ99624     614 YYLLVFSPSGSIIQYVLHHSAEPdSgidyp-sdaiS--YGSQRETDTRFVIEPLQKWDVCQKKNRRDTAE---------- 680  domesticated b...
XP_004244157 593 YHLLVFSSPGCVIQYSLRMCSGLdSlttttpvvatT--YESGVEVDTRLVVDAIQKWNICQKQNRKERg----------- 659  tomato
XP_010232446 580 YYLLVFSPSGSIIQYVLHHSDEQdSgidfp-sdaiS--YGSQRETETKFVIEALQKWDVCHKRNRRDTAE---------- 646  Brachypodium d...
BAD53258     463 YHLLVFSPSGSIIQYVLHRSAEQdPgidfp-ssaiP--YGSQRETDTRFIIEALQKWDVCHKRNRRDAAE---------- 529  Japanese rice
XP_004970215 574 YYLLVFSPSGSIIQYVLHLSTEQdSgfdfp-tgpiS--YGSERETDTKFVIEALQKWDVCHKRNRRDSAESf-------- 642  foxtail millet
ERM99845     509 HHLLVFSPCGFVIEYGLRLTPGEeRlktvsdasgpGniYESGQDQDMRLVIETLWKWNVSHRQNRAAEEE---------- 578  Amborella tric...
XP_006363524 537 HRLLVFSSPGCMTQYALRMCSELdSvatvp---amgstYE--ADLETKLVVEAIQKWNIFQKQNYKERDD---------- 601  potato
XP_011670337 406 PSLFIMSCHGFLVEYTLDPKAtl----------paS--VKKGDDSPLELVASMVAQWRLQRGFNSPECNLRip------- 466  purple sea urchin

Q8GUL1       652 yDLETVSNHLTS----HED---------ACLS-LdMNSHFSEdkylkscSekPPER-SHCYLSNFEVKVTSG-MLPVWQN 715  thale cress
XP_009402870 650 -NVDIYGDHGND----QSAkifq-kglrKGTSiYpAGSVVDMk-----gKlsGEET-HHAYLSEVELHVHEA-CTPLWAK 716  wild Malaysian...
BAJ99624     681 --SNLYNDFDSG----ENNkifq-kvvrKGTSiYpSNVAATEr-----lKlsTDEK-HNYYISESELQTHVA-QIPVWSR 746  domesticated b...
XP_004244157 660 gNMDIYGEFGDS----DNSkifp-ermkVENGlYsKISNTTTe-----eKrsSDER-HHMYISEVELEMHKR-QISLWAK 727  tomato
XP_010232446 647 --SYLYNDFDNG----LNSklfq-kvtrKGTSiYpSNCAATEr-----lKlsADEN-HNYYISESELQTHVV-QTPVWSK 712  Brachypodium d...
BAD53258     530 --SFVYSDFDIG----ENSklfq-kvakKGTSvYpSNGTAVEk-----qKl-GDEN-HNFYISESELQTHVV-PTPLWSR 594  Japanese rice
XP_004970215 643 ----aYNDFENG----ENNklfq-kvmkKGTSiYpFDSAAAEr-----pKlsADEN-RNFYISQSELQTHVV-QTPLWSR 706  foxtail millet
ERM99845     579 -NVDIYGESGDSykllPKGy-------kNSATvYpTNSGMPKr-----eRltSEEK-HHLYISNAELQMHHA-QTPIWVR 643  Amborella tric...
XP_006363524 602 -NADIYGEFGCS----DSSkvfp-egitKGNSlSsETRNTFTk-----eKirSEIG-HHIYISEAELQMHRP-HNQVWAK 668  potato
XP_011670337 467 gNSLVHLFSDDA----ERSitatqgslyQSLPrNeSCESLTSa-----hSsnQDTDfDEPWLSQVEMVTHAGpHRHLWMG 537  purple sea urchin

Q8GUL1       716 SKISFHVMDSP------------RDS-----SstGGEFEIEKVPAHELEI 748  thale cress
XP_009402870 717 SEVCFQVMIDE------------NIKehyssNi-HGEIEIEKITSCTIEt 753  wild Malaysian banana
BAJ99624     747 SGVHFQVIGSG------------TLEayatdNi-sGEIEIEKVQTHNVES 783  domesticated barley
XP_004244157 728 PEIYFQSFVAD------------EVKigdiyAf-GGETEIEEVPTHLVEA 764  tomato
XP_010232446 713 SGVHFQVIVGR------------TAEadnsdTv-sGETEIEKVWTRNIES 749  Brachypodium distachyon
BAD53258     595 SGMHFQVMGDG------------ALEadntgIi-sGELEIEKLQTRNIES 631  Japanese rice
XP_004970215 707 SGIHFQVMEGE------------TLEad-nlDitSGEVEVEKIQTHNIES 743  foxtail millet
ERM99845     644 PEMYFQVFLMD------------NVRmenlnDl-yEEIEIERVPTRTIEA 680  Amborella trichopoda
XP_006363524 669 PEVFFRSFVMD------------RIHldd---egGGEAEIEVIPTHIVEA 703  potato
XP_011670337 538 PQFVFKTVPQPssttilsssssaLLTegletNrsAMDMTIDDMDLRSLRI 587  purple sea urchin
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