Conserved Protein Domain Family
PE_PPE_C
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pfam12484: PE_PPE_C (this model, PSSM-Id:289267 is obsolete and has been replaced by 372141)
Polymorphic PE/PPE proteins C terminal
This domain family is found in bacteria, and is approximately 90 amino acids in length. The family is found in association with pfam00823. There is a conserved SVP sequence motif. There is a single completely conserved residue W that may be functionally important. The proteins in this family are PE/PPE proteins implicated in immunostimulation and virulence.
Links
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Statistics
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PSSM-Id: 289267
Aligned: 89 rows
Threshold Bit Score: 27.6606
Created: 28-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q73ZT6       292 AAGMGR-AQLVGSLSVPQGWaNAA-TINP--GQAAV----------PATGVTGLTDAAPAA-----GGPGGVAGPVGGtg 352 Mycobacterium a...
P9WHZ3       300 TADLGN-ASVVGRLSVPASWsTAApATAA--GAALDg---------TGWAV-PEEDGPIAVm---pPAPGMVVAANSVga 363 Mycobacterium t...
P9WI31       309 gASLGE-ATLVGRLSVPAAWsTAApATTA--GATALe--------gSGWTVAAEEAGPVTG-----MMPGMASAAKGTga 372 Mycobacterium t...
Q741T4       610 SAAVGE-ASAVGGLSVPASWsAAApATSLasSAAPLe--------gSGWTV-ASEAEPVTAm---pGMPGAAAAAKGAga 676 Mycobacterium a...
WP_013827938 191 SAGAGQpAARTTGAPLPPAWaGEPaPASA--TPATL----------SGTSTAAAAPRASTAav-paGLPASSSEQGSRgr 257 Mycobacterium s...
EUA86025      97 GAALGE-ATLVGKLAVPTSWsNALpETAA--TTGALg--------gSGWTV-PEEAAPVSGv---aGVPGMAAAAKGAga 161 Mycobacterium u...
WP_015355291 250 EAGLGQ-AAGVGKLSVPVGWsSAApALTS--GTTALd--------gSGWAV-PEESGPIAAm---pGGPGMAVAGKGGgf 314 Mycobacterium
WP_013827943 339 SAGVGQ-ATLVGELSAPPAWaAAApAGTA--ATGDAl---------QASSWSAAPEEIESMaampgGMPLGADRSGFGlg 406 Mycobacterium s...
WP_013831156 319 SAGVGR-ATLVGSLSAPPSWgTAVpAAAP--SAGTA----------SGWTVAPDSRSVTAMpp--pMLPNGGGRSGSFgl 383 Mycobacterium s...
AEF35597     305 LAHMGGdAAPVGQLSVPPAWaDATpVGAA--TKEPVwlsdaeladtSEGGAVADMPGASPAv---gMGPMAAMMAGGAag 379 Mycobacterium s...

Q73ZT6       353 rrlrraipkygfrpvvmpRP 372 Mycobacterium avium subsp. paratuberculosis
P9WHZ3       364 dsgpry----gvkpivmpKh 379 Mycobacterium tuberculosis H37Rv
P9WI31       373 yagpry----gfkptvmpKQ 388 Mycobacterium tuberculosis H37Rv
Q741T4       677 ygsgpry---gfkpivmpKQ 693 Mycobacterium avium subsp. paratuberculosis
WP_013827938 258 lrygi-------kpkvmpRP 270 Mycobacterium sp. JDM601
EUA86025     162 yagpry----gfkpivmpKQ 177 Mycobacterium ulcerans str. Harvey
WP_015355291 315 agpryg-----fkptvmpKQ 329 Mycobacterium
WP_013827943 407 tpryg------fkptvmaRP 420 Mycobacterium sp. JDM601
WP_013831156 384 gtpryg-----tkltvmpRP 398 Mycobacterium sp. JDM601
AEF35597     380 rqtvagalrvapsrfkmpRP 399 Mycobacterium sp. JDM601
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