3F1I


Conserved Protein Domain Family
Hrs_helical
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pfam12210: Hrs_helical (this model, PSSM-Id:289018 is obsolete and has been replaced by 463493)
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Hepatocyte growth factor-regulated tyrosine kinase substrate
This domain family is found in eukaryotes, and is approximately 100 amino acids in length. The family is found in association with pfam00790, pfam01363, pfam02809. This domain is the helical region of Hrs which forms the core complex of ESCRT with STAM.
Links
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Statistics
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PSSM-Id: 289018
Aligned: 22 rows
Threshold Bit Score: 119.305
Created: 21-Jul-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3F1I_H         4 QFLKALQNAVTTFVNRMKSNHMRGRSITNDSAVLSLFQSINGMHPQLLELLNQLDERRLYYEGLQDKLAQIRDARGALSA 83  human
GAA40636     209 EFLNALRASVEFFVNRMQSNSQRGRSIANDTTVQALFLTLHEMHPQLLQYKQAMEERRAYFEGLQDKITQLRDAREALDA 288 Clonorchis sine...
XP_012800864 343 EFLDALRGSIEFFVNRLQSNSQRGRNISSDTTVQTLFLTLNKMHPQLMDYKHYMEERRAYFEKMQDKLNQIREAREALDA 422 Schistosoma hae...
XP_003379497 409 DFVNSLNESISVFVNRIKSNQTRGRSVTADDTIQNNFIALTSMHSRLLKNMQDRIDRREYYENLQDKVNQIREAREALES 488 Trichinella spi...
XP_001636928 134 TLVNNFRSSVEMLMERMQDISGKGKHVAMDATVQSLFQTVSAMHPQLLRLVEQQEQETGKYEGIQERLGLVKEARATLEG 213 starlet sea ane...
XP_001897342 436 eFCRQLVEQVTVMDNRIRSNVARNRSVVNDTAIQSLFIRLTEMHAQVMARMNKLEDQRNHFESLQDSLAHIQEARQAIDA 515 Brugia malayi
CBY18102     421 kflkNLSASLDIFANRMRANQARGKPIASDATVQTLFQQVSNLQPTLLQNMAEAEERRTHWEQLNDKVTMIHEARNALNA 500 Oikopleura dioica
XP_004346143 442 EILETMKASLTLFEEKLQQAAMKGVPLNQDASVKSLFQTLSVMHPRLMKRIEENEELRREFTAVEQDLDKVQEAKKTLDE 521 Capsaspora owcz...
CDJ01802     423 EFLTALRKSLDVFSNRMRVCSQRGRQVATDSTLQTLFKTLHQMNLQLMQYSNDLEVRRTSLEKLQDQTAQIREAREALDD 502 Echinococcus mu...
KKA74120     196 qfcdqvkeQVTMMDSRIRSNVARGRSIINDSAILPLFEKLTNWHGEVLARMAKLDEDRAHLESLQDHLAHIGEARQAMDA 275 Pristionchus pa...

3F1I_H        84 LREEHREKLR-RAAEE 98  human
GAA40636     289 LRQEHAARRQ-LEEQE 303 Clonorchis sinensis
XP_012800864 423 LRHDHAVRKQ-IEEQE 437 Schistosoma haematobium
XP_003379497 489 LREEYRDKKK-VELAE 503 Trichinella spiralis
XP_001636928 214 AREAHREKLR-QQELE 228 starlet sea anemone
XP_001897342 516 LREDHERQKQaRIMEE 531 Brugia malayi
CBY18102     501 LRTEHKAEMR-RKAEE 515 Oikopleura dioica
XP_004346143 522 IRRQHQVKLK-QQQEE 536 Capsaspora owczarzaki ATCC 30864
CDJ01802     503 LRRDYaeqrrreeeea 518 Echinococcus multilocularis
KKA74120     276 LREEHGRRMR-EEEEE 290 Pristionchus pacificus
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