2KLU


Conserved Protein Domain Family
Tcell_CD4_C
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pfam12104: Tcell_CD4_C (this model, PSSM-Id:288921 is obsolete and has been replaced by 403359)
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T cell CD4 receptor C terminal region
This domain is the C terminal domain of the CD4 T cell receptor. The C terminal domain is the cytoplasmic domain which relays the signal for T cell activation. This process involves co-receptor internalisation. This domain is involved in binding to the N terminal of Lck co-receptor in a Zn2+ clasp structure.
Links
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Statistics
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PSSM-Id: 288921
Aligned: 4 rows
Threshold Bit Score: 51.1591
Created: 1-May-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2KLU_A        38 RRQAERMSQIKRLLSEKKTSQSPHRFQK 65  human
ARU07050     455 RQRAKRMARARQYLLEKKTCQCQHRMNK 482 mallard
AAR13802     426 RRQAERMSQIKRLLSEKKTCQCPHRFQK 453 Cloning vector pMACSiBac
XP_015148650 460 RKRARRMAQAKQYLLEKKTCQCQRRMYK 487 chicken
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