Conserved Protein Domain Family
GATA-N
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pfam05349: GATA-N (this model, PSSM-Id:283099 is obsolete and has been replaced by 461628)
GATA-type transcription activator, N-terminal
GATA transcription factors mediate cell differentiation in a diverse range of tissues. Mutation are often associated with certain congenital human disorders. The six classical vertebrate GATA proteins, GATA-1 to GATA-6, are highly homologous and have two tandem zinc fingers. The classical GATA transcription factors function transcription activators. In lower metazoans GATA proteins carry a single canonical zinc finger. This family represents the N-terminal domain of the family of GATA transcription activators.
Links
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Statistics
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PSSM-Id: 283099
Aligned: 33 rows
Threshold Bit Score: 102.134
Created: 26-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q61169       147 MYQTLAALSSQGPA-AYDGAPGGFVH--SaaaaaaaaaA--A-S-SPVYVPTTRV-GSMLSGLPYLQGAGsGPSNHaGGA 218 house mouse
CCP19132       1 MYQSLAMAANHGPP-SY-EGAGSFMH--T---------A--AgS-SPVYVPTTRV-NPIIPNLPYLQSTGaSQQVSpVs- 62  Menado coelacanth
XP_006633923 115 MYQTLAIAASQGPA-GYDSSAGSYMH--S---------T--A-P-SPVYVPTTRV-GPMIPSIPYLQGSGsSQPGHaVs- 176 spotted gar
NP_001016949   1 MYQSIAMAANHGPP-AY-EGAGGYMH--S---------AtaA-T-SPVYVPTTRV-SSMIPSLPYLQTSGsSQQGSpVs- 63  western clawed ...
XP_008120695   1 MYQSLAMAANHGPP-SYEGASG-FMH--Sa--------A--A-A-SPVYIPTTRV-TSMISSLPYLQGSAsSQQGSpVs- 62  green anole
XP_005044496   1 MYQSLAMAANPGPP-AY-EGAGGFMH--S---------A--A-AaSPVYVPTTRV-TSMLPSLPYLQSSAsSQQGSpVs- 62  collared flycat...
XP_006642996   1 MYQGIAMTTNHGAP-SY---ESRFMH--S---------A--AaT-SPVFVPTTRA-TPMIPALPYLQPHAaSQQNSpVc- 60  spotted gar
XP_003971721   1 MYQGI-MTSNHGPP-SY---EAGFLHntS---------A--A-T-SPVYVPTTRVvTPMIPALPYLQTPGaSQQSSpVs- 61  torafugu
NP_001266556   1 MYQGI-MTSNHGPS-SY---EAGFLHnaS---------T--G-T-SPVYVPTTRVvTPMIPALPYLQTPGaSQQSSpASS 62  Nile tilapia
XP_007238766   1 MYQGLTISATHHAAhSYEASFLPSVG--S---------T--A-R-SPVYVPSPRV-PAVLPALPYLQAHGa-PHHGaSSS 63  Mexican tetra

Q61169       219 gaHPGW-SQ---------ASADS-PPYGGggaagggaagpggagsATAH-A---SARFPYSPSPPMANG--AARDp-GG- 279 house mouse
CCP19132      63 -sHSAW-AQ---------PGAES-AAYNH----------------GSSH-Pp-vSPRFAFSTSPPITAS--SSRE--AV- 107 Menado coelacanth
XP_006633923 177 -sHSVW-PQ---------PAPES-PSYSA----------------SSPH-A---SNRYHYSPSPPMNNG--ASRD--SG- 219 spotted gar
NP_001016949  64 -gHNMW-AQ---------AGAEP-SAYNP----------------GTSH-Pp-vSPRFTFSSSPPISAA--SNRE--VP- 108 western clawed ...
XP_008120695  63 -sHSIWtPQ---------PGAES-VAYNP----------------GSSH-Ps-vSPRFSFATSSPIAAT--TSREv-AA- 109 green anole
XP_005044496  63 -sHSIW-TQ---------PAAES-AAYNP----------------GSSH-Pp-vSPRFSFSTSTPIPAT--SSREaaAA- 109 collared flycat...
XP_006642996  61 -sHSGW-AQ---------STEEPvPSYTT----------------GGSH-QstmSPRFTFSTSPPISAAvaAVRDn-AT- 110 spotted gar
XP_003971721  62 -sHSAW-AQ---------PGSDS-VSSYS----------------HSPv-----SPRFAFSTSPPLSSGvaAAREtaAS- 107 torafugu
NP_001266556  63 hsAW---AQ---------PGADSvPSYN--------------------H-Sp-vSPRFTFSTSPPLSSGvaTARE--TAv 106 Nile tilapia
XP_007238766  64 saHSAW-AQdpgssssspPSSYS-AGGSG----------------NTAHaPp-vSPRFVFSANSPLCSG----------- 113 Mexican tetra

Q61169       280 -YvaaggtgagsvsgggGSLAAM--GGRehQYSSlsaARPLNGTYhhhhhhhPtYSP-YMAAPLTPAWPAGPFETPVLHS 355 house mouse
CCP19132     108 -Y---------------SSPLAIsgNGRe-QYN-----RSLSGSYp-----nP-YPT-YMSPDIGTAWTAAPFDSSMLHN 158 Menado coelacanth
XP_006633923 220 -Y---------------SNTLNV--NGRe-QYSTl--TRSLSGSYp-----sP-YSP-YVGPQLSAAWPSGPFENTMLHT 271 spotted gar
NP_001016949 109 -Y---------------SSPLAIsaNGRe-QYG-----RALGATYs-----sP-YPA-YMSPDMGATWTASPFDSSMLHN 159 western clawed ...
XP_008120695 110 -Y---------------SSSLSItaNSRe-QY-----ARNFGGSYs-----sH-YPAtYMSPELGSTWTASHFENPMLHN 161 green anole
XP_005044496 110 -Y---------------SSSLNLsaNGRe-QYG-----RGFGSSYs-----sP-YPA-YMSPEMATSWTSSPFDSPMLHN 160 collared flycat...
XP_006642996 111 -Y---------------PSPLNIsaNGRe-QYGT----RGLGGSYh-----sP-YPA-YVSPSMGGGWTTSPFDSSVLHS 162 spotted gar
XP_003971721 108 -Y---------------TNALNIsaNGRe-HYGP----RSLGGSYh-----sP-YTP-YMSPNVGGTWPASPFDSPVLHG 159 torafugu
NP_001266556 107 sY---------------TSPLNIsaNGRd-HYSA----RGLSGSYh-----sP-YSA-YMSPNVGGTWPASPFDSPVLHG 159 Nile tilapia
XP_007238766 114 -M---------------TGTLDTpaGG------Ar--GLGMGPSYhp----sP-YPA-YVSPGMGGTWAASHFDSSVLHG 163 Mexican tetra

Q61169       356 LQGRaGAPLPVpRGPST 372 house mouse
CCP19132     159 LQNR-GAPGPA-RHPNL 173 Menado coelacanth
XP_006633923 272 LQTR-GAPLPI-RGPGG 286 spotted gar
NP_001016949 160 LQNR-AGPAAS-RHPNI 174 western clawed frog
XP_008120695 162 LPNR-GSPGAA-RHGNL 176 green anole
XP_005044496 161 LQSR-GTPAAA-RHANI 175 collared flycatcher
XP_006642996 163 LQPG-GAPGTA-RHPSI 177 spotted gar
XP_003971721 160 LQSG-TATGAA-RHPNI 174 torafugu
NP_001266556 160 LQAG-APPGTA-RHPNI 174 Nile tilapia
XP_007238766 164 LQSG-DQNPVA-RHPDL 178 Mexican tetra
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