1OY5,4JWJ,4JWF


Conserved Protein Domain Family
tRNA_m1G_MT
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pfam01746: tRNA_m1G_MT (this model, PSSM-Id:280003 is obsolete and has been replaced by 396350)
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tRNA (Guanine-1)-methyltransferase
This is a family of tRNA (Guanine-1)-methyltransferases EC:2.1.1.31. In E.coli K12 this enzyme catalyzes the conversion of a guanosine residue to N1-methylguanine in position 37, next to the anticodon, in tRNA.
Links
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Statistics
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PSSM-Id: 280003
Aligned: 15 rows
Threshold Bit Score: 181.389
Created: 25-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1OY5_B  28 KQAIKKGKVEVYPIDLREFAPKGQ--VDDVPYGGLPGMVLKPEPIYEAYDYVven-----ygKPFVLITEPWGEKLNQKL 100 Aquifex aeolicus
P0A4P1  22 GKARARGQLGVHVHDLRDWTYDRHntVDDTPYGGGPGMVMKTEPWGDALDSVladgyetgcgEPALVVPTPSGRPFTQEL 101 Streptomyces coelicol...
O33017  22 GKAIESGLVDVQVHDLRRWTHDVHhsVDDVPYGGGPGMVMKAPVWGEALDEIcf-------dETLLVIPTPAGALFTQAT 94  Mycobacterium leprae TN
Q32CY1  23 GRAVKNGLLSIQSWSPRDFTHDRHrtVDDRPYGGGPGMLMMVQPLRDAIHAAkaa----ageGAKVIYLSPQGRKLDQAG 98  Shigella dysenteriae ...
P72828  23 GKALEKAIASVNLINPRDFTTDKHrrVDDEPYGGGVGMVIKPEPIFAAVESLpv------lsKREVILMTPQGQPMDQAL 96  Synechocystis sp. PCC...
O31741  23 QKAQEKDAVQFQVVNFREYSDNKHntVDDYPYGGGAGMVLKPQPVFDAVEDLtsk----aaaAPRIILVCPQGERFTQKK 98  Bacillus subtilis sub...
Q9VR56 105 DLMQERDIVKCVKQCLRIYTINRRspQPGNLHFTGIRRNGHIHESFKKNE------------GWENWHVQYY----FDRG 168 fruit fly
4JWJ_B  31 ELMNDKEIVSLSNQVTRAYSANRRanHFAEIKVAPFDKRLKQRFETTLKNTny--------eNWNHFKFLPDDKIMFGDE 102 Saccharomyces cerevis...
4JWF_A  41 DLXNDKEINSLCQQVTRCHSANRTalHPVELFATNFGGRLKTRQDFVLKGQQn---------NWKRYNPTTK--SYLEEF 109 Schizosaccharomyces p...
Q3UFY8 208 NYMKPSELQNTVSQLLESEGWNRRnvDPFHIYFCNLKIDSAYHRELVKRYRE----------KWDKLLLTAT-----EKS 272 house mouse

1OY5_B 101 VNELSKKERIMIICGRYEGVDERVKKIVd-----mEISLGDFILSGGEIVALAVIDAVSRVLPGVLsePQSIQEDSFqn- 174 Aquifex aeolicus
P0A4P1 102 AVHLSERPWLIFTPARYEGIDRRVVDEYatrmpvyEVSIGDYVLAGGEAAVLVVTEAVARLLPGVLgnAESHRDDSFapg 181 Streptomyces coelicol...
O33017  95 AQCWSTERHLVFACGRYEGIDQRVVDDAvrrmrveEVSIGDYVLPGGESAAVVMIEAVLRLVAGVLgnPASHRDDSHspd 174 Mycobacterium leprae TN
Q32CY1  99 VSELATNQKLILVCGRYEGIDERVIQTEid----eEWSIGDYVLSGGELPAMTLIDSVSRFIPGVLghEASATEDSFae- 173 Shigella dysenteriae ...
P72828  97 FRELTNYDQLVLICGHYEGVDERVCQLVt-----rEVSLGDFVLTCGEIPALTLINGVIRLLPGTVgkEASLIAESFst- 170 Synechocystis sp. PCC...
O31741  99 AEQLAKEEHLLFICGHYEGYDERIREHLvt----dEISIGDFVLTGGELPAMMIADSVVRLLPGVLgkEASHIEDSFst- 173 Bacillus subtilis sub...
Q9VR56 169 HTDIFEHSQLVYLTCESDRVLDKLQPGC-------TYVIGGLVDHNHFKGL----CHSRATSAGLT--TARLPLSEH--- 232 fruit fly
4JWJ_B 103 HI---SKDKIVYLTADTEEKLEKLEPGM-------RYIVGGIVDKNRYKEL----CLKKAQKMGIP--TRRLPIDEY--- 163 Saccharomyces cerevis...
4JWF_A 110 E---SQKEKLVYLSADSDNTITELDEDK-------IYIIGAIVDKNRYKNL----CQNKASEQGIK--TAKLPIDEY--- 170 Schizosaccharomyces p...
Q3UFY8 273 PVDLFPKDSIIYLTADSPNVMTTFKHDK-------IYIIGSFVDKNTQTGT----SLAKAKRLNIA--TECLPLDKY--- 336 house mouse

1OY5_B 175 ---rWLGYPVYTRPREYRgmKVPEELLSGHHklIELWklWHRIENTVKKRP 222 Aquifex aeolicus
P0A4P1 182 amanLLEGPVHTKPPQWRgrGIPDVLLSGHHgkIARWrrDEALRRTTANRP 232 Streptomyces coelicolor A3(2)
O33017 175 -lgrLLEGPSYTRPPTWRglDVPPVLLSGDHarIAAWrrEASLRRTRKRRP 224 Mycobacterium leprae TN
Q32CY1 174 ---gLLDCPHYTRPEVLEgmEVPPVLLSGNHaeIRRWrlKQSLGRTWLRRP 221 Shigella dysenteriae Sd197
P72828 171 ---dLLDYPHYTRPPVFRglAVPPVLLSGNHqaIAQWrlEQQEERTQQRRP 218 Synechocystis sp. PCC 6803 substr. Kazusa
O31741 174 ---gLLEHPHYTRPADYKglKVPETLLSGNHakIEEWrnKESIRRTYLRRP 221 Bacillus subtilis subsp. subtilis str. 168
Q9VR56 233 ----VDMKT--RAVLSTY--HVFELLTKVAA--GQDW--TTAILETIPMRK 271 fruit fly
4JWJ_B 164 ----INLEG--RRVLTTT--HVVQLMLKYFD--DHNW--KNAFESVLPPRK 202 Saccharomyces cerevisiae S288c
4JWF_A 171 ----IKITD--RKILTVN--QVFEILSLWLE--YRDW--EKAFXEVIPKRK 209 Schizosaccharomyces pombe 972h-
Q3UFY8 337 ----LQWEIG-NKNLTLD--QMIRILLCLKN--TGNW---EEALKFVPRRK 375 house mouse
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