2M4N,4KVG,1WGR,1RAX


Conserved Protein Domain Family
RA
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pfam00788: RA (this model, PSSM-Id:279168 is obsolete and has been replaced by 425871)
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Ras association (RalGDS/AF-6) domain
RasGTP effectors (in cases of AF6, canoe and RalGDS); putative RasGTP effectors in other cases. Recent evidence (not yet in MEDLINE) shows that some RA domains do NOT bind RasGTP. Predicted structure similar to that determined, and that of the RasGTP-binding domain of Raf kinase.
Links
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Statistics
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PSSM-Id: 279168
Aligned: 42 rows
Threshold Bit Score: 61.5677
Created: 13-Jun-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2M4N_A    3 FGGSLKVYGGEIVPTRpYVSILAEINENADRILGAALEKYGL------EHSKDDFILVevsndddrksmSDLREIDGRPI 76   Caenorhabditis elegans
Q02833    6 AAMELKVWVDGIQ----RVVCGVSEQTTCQEVVIALAQAIGQ---------TGRFVL------------VQRLREKERQL 60   human
Q8K4S1 2115 ESFFVQVHDVSPEQP--RTVIKAPRVSTAQDVIQQTLCKAKYsysilnNPNPCDYVLLeevlkdaankkSSTPKSSQRIL 2192 house mouse
Q8R5G7 1113 GDLIMEVYIEQQLPDN-CVTLKVSPTLTAEELTNQVLEMRGA------ASGTDLWVTFe----------ILEHGELERPL 1175 house mouse
Q96P48 1172 GDFICTVYLEEKKAET-EQHIKVPASMTAEELTLEILDRRNVg-----IREKDYWTCFe----------VNEREEAERPL 1235 human
Q03160   99 RLCVVKVYSEDGA----CRSVEVAAGATARHVCEMLVQRAHA-------LSDESWGLVe----------SHPYLALERGL 157  house mouse
O88900  104 KKQVIKVYSEDET----SRALEVPSDVTARDVCQLLILKNHY-------VDDNSWTLFe----------HLSHTGVERTV 162  Norway rat
4KVG_B    2 KKLVVKVHMDDSS----TKSLMVDERQLARDVLDNLFEKTHC-------DCNVDWCLYe----------IYPELQIERVF 60   house mouse
Q8K4V4  271 SDVELRVALPDGA----TVTVRVKKNSTTDQVYQAIAAKVGMd-----STTVNYFALF-----------EVINHSFVRKL 330  Norway rat
Q9W486  277 SPVDIKVMLPDHE----VSTVSVKKSSNAQVVWEILVQRANLt-----AYTQQYFYLF-----------EIVEYNFERKL 336  fruit fly

2M4N_A   77 PPTECPLFEMTARSGNGenGFDSFLAIKRKP 107  Caenorhabditis elegans
Q02833   61 LPQECPVGAQATCGQFA--SDVQFVLRRTGP 89   human
Q8K4S1 2193 LDQECVFQAQSKWKG-----AGKFILKLKEQ 2218 house mouse
Q8R5G7 1176 HPKEKVLEQALQWCQLPepCSASLLLRKVSM 1206 house mouse
Q96P48 1236 HFAEKVLPILHGLGT-----DSHLVVKKHQA 1261 human
Q03160  158 EDHEFVVEVQEAWPVGG---DSRFIFRKNFA 185  house mouse
O88900  163 EDHELLTEVLSHWVMEE---DNKLYLRKNYA 190  Norway rat
4KVG_B   61 EDHENVVEVLSDWTRDT--ENKVLFLEKEER 89   house mouse
Q8K4V4  331 APNEFPHKLYVQNYTSAv-PGTCLTIRKWLF 360  Norway rat
Q9W486  337 QPHEIPHQLYVQNYSTA--SSTCLCVRRWLF 365  fruit fly
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