1EX4


Conserved Protein Domain Family
IN_DBD_C
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pfam00552: IN_DBD_C (this model, PSSM-Id:278951 is obsolete and has been replaced by 425747)
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Integrase DNA binding domain
Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain. The central domain is the catalytic domain pfam00665. This domain is the carboxyl terminal domain that is a non-specific DNA binding domain.
Links
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Statistics
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PSSM-Id: 278951
Aligned: 9 rows
Threshold Bit Score: 69.3323
Created: 6-Jul-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1EX4_A    172 QNFRVYYRDSRNSLWKGPAKLLWKGEGAVVI---QDNSDIKVVPRRKAKII 219  Human immunodeficiency virus 1
P14078   1393 HWYYFKLPGLNSRQWKGPQEALQEAAGAALIp--VSASSAQWIPWRLLKRA 1441 Human T-cell lymphotrophic virus type 1 (Carib...
Q0R5R2   1371 KWYYYKIPGLTNSRWSGPVQSLKEAAGAALIp--VGGSYL-WIPWRLLKRG 1418 HTLV-3 strain 2026ND
P11283   1651 PKPMVMWKDLLAGSWKGPDVLITAGRGYACVf-pQDAETPIWVPDRFIRPF 1700 Mouse mammary tumor virus (STRAIN C3H)
P18096   1391 KNFQVYYREGRDQLWKGPGELLWKGEGAVIV---KVGTDIKVVPRRKAKII 1438 Human immunodeficiency virus type 2 (ISOLATE BEN)
EGW11815   64 PHGMVKWKDILSGLWCGPDPVLTWARGSVCVf-pQDQQDPVWVPERLIRKI 113  Chinese hamster
ABV71114  714 KKPLVRWKDPLTNLWYGPDPVLIWGRGHVCVf-pQDAEAPRWIPERLVRAA 763  sheep
CAA34658  325 PNEMVKWKNVLDNKWYGPDPILIRSRGAVCVf-pQNEDNPFWIPERLTRKI 374  house mouse
EGV97962   14 TFAQVKWKDHCTGLQKGPDPVLIWGRGHVCLffsQEENEVQWLPECLVRCV 64   Chinese hamster
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