1VPM,1Y7U


Conserved Protein Domain Family
BFIT_BACH
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cd03442: BFIT_BACH 
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Brown fat-inducible thioesterase (BFIT). Brain acyl-CoA hydrolase (BACH). These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis, and brown adipose tissues. The archeal and eukaryotic members of this family have two tandem copies of the conserved hot dog fold, while most bacterial members have only one copy.
Links
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Statistics
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PSSM-Id: 239526
Aligned: 205 rows
Threshold Bit Score: 69.1349
Created: 7-Mar-2002
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1VPM_C       17 YPVERSRTIQTRLVLPPDTNHLGTIFGGKVLAYIDEIAALTAXKHANs-AVVTASIDSVDFKSSATVGdALELEGFVTHT 95  Bacillus halodur...
Q8WXI4      213 VPAEKTRVESVELVLPPHANHQGNTFGGQIMAWMENVATIAASRLCRa-HPTLKAIEMFHFRGPSQVGdRLVLKAIVNNA 291 human
AAH74196    200 ILTDSTRVESIELVLPPHANHQGNTFGGQIMAWMETVANISASRLCRt-HATLKSVDMFKFRGPSTVGdRLLFRAIVNNT 278 African clawed frog
XP_426664   386 VPAEKTRVESVELVLPPHANHQGNTFGGQIMAWMENVATIAASRLCHa-HPTLRAIEMFHFRGPSQVGdRLVLKAIVNNA 464 chicken
AAX79331    216 VPIASTRTSAHRIFLLYHLNNNRTIFGGELMRWMERHAVHCGRMFTGnrHISTVAMHNVEFHHPVFGTdWVTLEADIIYV 295 Trypanosoma brucei
AAH95856    196 VPTERTRVESVELVLPPHANHQVNTFGGQIMAWMENVATIAASRLCNa-HPTLRAIDMFHFRGPSQVGdRLILKAIVNNT 274 zebrafish
XP_758294   532 IKVAKTMARTLHLVFPEHTNSVGVLFGGQLMDWMEEAALLSVRHVGRgrRWGTVSLDGLEFEQAVAVGeSMTFTAVVVRT 611 Ustilago maydis 521
ABA88613    197 LLASKLTADAWERMYPEQENVPQKIFGGYLIRRAYELASICSEQVAPn-RPIPAAVNRINFFHPVRMGdKLHYTARVVYT 275 Pelobacter carbi...
ZP_00551232 196 LLSGKLVADSWERMYPAKENVPTTIFGGYLMRRAYELSSICAELVAPn-RPVIVAVNRVNFFHPVRLGdKLHYTCRVVYT 274 Desulfuromonas a...
ZP_00676624 207 IRAGQLVLESTCRAYPEQENVPKTIFGGYLIRKAYELAALAAEMVAPn-RAVPCQVNRINFNQPVLLGdQLKFTARVVYT 285 Pelobacter propi...

1VPM_C       96 GRTSXEVYVRVHSNNll------------------------tgERTLTTESFLTXVAv-dESGKPKPVP 139 Bacillus halodurans C-125
Q8WXI4      292 FKHSMEVGVCVEAYRqea-----------------------etHRRHINSAFMTFVVl-dADDQPQLLP 336 human
AAH74196    279 FQKSVEVGVRVEAFNceew---------------------tgaNGRHINSAFLIYQAl-nSKGEYRMFP 325 African clawed frog
XP_426664   465 FKNSMEVGVCTEAYEqemsvsrrhinsafxtfxvlxrragparCPWHINSAFMTFVVl-dEEGRPRTLP 532 chicken
AAX79331    296 HNTTMEVDVKLVVERd--------------------------gHVVTTNRASFVLINl-nEIGQKTIIP 337 Trypanosoma brucei
AAH95856    275 FKNSMEVGVCAEAYIge-------------------------ePLRHINSAFMTFEVl-dDKGRPRPLP 317 zebrafish
XP_758294   612 FVQSCEVFVLAEAESrn-------------------------gTKRITNDALFTLAFpldESEILSPVK 655 Ustilago maydis 521
ABA88613    276 NGSLICVEANIERISrd------------------------rtTKAMSNSCLFTFVNv-dEELQRQPVP 319 Pelobacter carbinolicus DSM...
ZP_00551232 275 GKTSISVEANIRRISrd------------------------rtSEALSNSCLFTFVNv-dDHLNPLPVP 318 Desulfuromonas acetoxidans ...
ZP_00676624 286 GRTTVTVQSDIERFNrn------------------------agDKSLSNSCLFTFRNv-dSDMQPQPVP 329 Pelobacter propionicus DSM ...
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