1DP2,1E0C,1ORB,1URH


Conserved Protein Domain Family
TST_Repeat_1
?
cd01448: TST_Repeat_1 
Click on image for an interactive view with Cn3D
Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it is believed to be involved in protein interaction.
Links
?
Statistics
?
PSSM-Id: 238725
Aligned: 75 rows
Threshold Bit Score: 89.2156
Created: 22-Jun-2004
Updated: 2-Oct-2020
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
 
active site
Conserved site include 1 residue -Click on image for an interactive view with Cn3D
Feature 1:active site residue [active site]
Evidence:
  • Comment:Lacks Cys, the active site residue for sulfurtransferase activity
  • Comment:in rhodanase this domain is duplicated, but only the second repeat has the active site Cys.
Download Cn3D for Viewing 3D StructureScroll to Sequence Alignment Display
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                                                     
1DP2_A      9 LVSTKWLAESVragk-----vgpgLRVLDASwyspgt---------------------rearkEYLe-RHVPGASFFDIe 61  cow
NP_691453   4 LISVQRLMRRFsq---------nqIVIVDVRfdlqdp---------------------dagrkAYLk-EHIPGAIYMDLn 52  Oceanobacillus ihe...
B70455     20 LISPEELHKLIkee--------knLVIIDLRks----------------------------ikEYWk-EHIPGAQWVHFe 62  Aquifex aeolicus
T23071     42 IIDASYVETAAlnnakf-ntnhpeIIISDIKsp-----------------------------dLYTd-EHIPGAVHFDLd 90  nematode
CAB07429    6 IVTPQWLMQNVn-----------kVRLIDATyaptatrdykefktk--cygnfdlltknntvaAYTg-EHIPGAAHFGLd 71  nematode
P91247      6 IVEPKWVVQNFg-----------nIRILDASwtfkpkadvaeykak--yynkfgvgmnelknpEYLa-EHINGAAHFNFd 71  nematode
O17730      6 IIDVKSVNTLLkkgii----nkegVRIIDCSfavaprpdwkefeqegygdfknlmaepspsrnLYLa-GHIPEAVHVDLd 80  nematode
NP_506242  13 EMTPNHLLTLLitk--------rkICILEAAsgdea-----------------------ksrdAFSv-DHIESARLIFHs 60  nematode
Q08686      6 LISPKAFVKLVasek------vhrIVPVDATwylpsw--------------------kldnkvDFLtkPRIPNSIFFDId 59  baker's yeast
EAA50328   42 LVTPKEVHEAMqksppssisthprVICLNAAwflpndp------------------egrtgieSYRk-TRIPKSRFFDLd 102 Magnaporthe grisea...

Feature 1                                             #                                       
1DP2_A     62 ecrdka---spyevmLPSEAGFADYVGSLGISNDTHVVVYDGDdl-gSFYAPRVWWMFRVFGHrtVSVLNGGFRNWLKEG 137 cow
NP_691453  53 kdlsgkagkhggnhpLPDWELFANKLGQIGITNETIVVVYDQGn---DMFAPRFWWLMDYVGHdkVYILEGGLDQWKEEG 129 Oceanobacillus ihe...
B70455     63 afrfpk---ggtpafFLHTEIFVKKLEKLGIDKNTPVVLYDAEg---TFIPFYVAWGLDYINHkkVYVLHGGFNHWKDKD 136 Aquifex aeolicus
T23071     91 igsyss---eyikhdLYPPEHFQKYLRLLGVNNGDQLVIYSNGpasgMKFASRAYWTFKMYGFttVSLLNGGMDVWKAAG 167 nematode
CAB07429   72 sayfps---qyikfdLYPPEHFEKYLRLLGINNDEQVVIYSRGpaagMMFASRAYWTLKAYGLtnLSLLNGGLDAWKAAG 148 nematode
P91247     72 iayyps---ederftLYTPEEFSSYVKRLGVFNGDHLVIYGRGkdggMAAASRAYWTFRYYGYttVSVLNGGIEAFKLAQ 148 nematode
O17730     81 iatyps---ryqrfqQYRADLFEEYAQMVGLNNKEHFIFYGKGafggMLFASKVAWIFKSYGHenISLVDGGFDSWKRNG 157 nematode
NP_506242  61 nls--------hagvPVHPLQFQRFARSQGIDNDCHVIVYDRGq---MIWSSYTVWIFKLFGHqkVSLLSGGYLGWKTHQ 129 nematode
Q08686     60 aisdkk---spyphmFPTKKVFDDAMSNLGVQKDDILVVYDRVg---NFSSPRCAWTLGVMGHpkVYLLNNFNQYREFKY 133 baker's yeast
EAA50328  103 kvidrh---spyphmLPEPKSFASAMSELGVRREDTVVVYDTKel-gIFSAPRVAWTLRVFGHpkVHILNNFRAWCDEEL 178 Magnaporthe grisea...

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap