Conserved Protein Domain Family
SXM1

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COG5656: SXM1 
Importin, protein involved in nuclear import [Posttranslational modification, protein turnover, chaperones]
Statistics
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PSSM-Id: 227943
Aligned: 4 rows
Threshold Bit Score: 1267.47
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1171739     2 DITELLQCFACTLDHNAAVRTNAETHLKNASKVPGFLGACLDIIAADEVPENIKLSASLYFKNKITYGWSAgarqgsneL 81   baker's yeast
19074671    1 MREETRQIFLQTIDSDAGKRSIAEAMLMDLEKQPGFVMSLPHTCMKD-GDPIVKRVAAIYFKNAIIKQWRS--------- 70   Encephalitozoon c...
19075603    1 --MSLVEHFDATLSADPNTRTKAELSLKQLEKEPSFVLAVLQLLSSQEISLPTQQAAVIYLKNRVSRSWSS--------I 70   fission yeast
6320603     3 QEQAILSCIEQTMVADAKIIKEAEQQLFEFQKQPGFTSFLLNIVSDDNFALNVRLSSAIYLKNKIHRSWDT--------K 74   baker's yeast
1171739    82 LDSHVDPDEKPVVKDMLIKTMVSVSKTSPRCIR-VLKSALTVIISEDYPSKKWGnLLPNSLELLANEDITVTYVGLLCLA 160  baker's yeast
19074671   71 -N------EYSEARKYLVENILDLFLYGDEVTRtAYNAILVNIFNNEKLSDLDG-MFRKAAGFMRTSEANHVLTALNMYE 142  Encephalitozoon c...
19075603   71 DDAPSPLDIPEEQKALFRQNILPVLLQSPMSTRsHLMAILNIILSTDFP-EYWPgFSEYTSNLVHSTERCEVYAGLICFH 149  fission yeast
6320603    75 REDGIKADEKLSIKERLIETLVKNCENNHIRPIlTETINGILVGQEDWD------LAPIIKNLLSSGDASYIYPGLLLLF 148  baker's yeast
1171739   161 EIFRTYRWKNNDERQDLEELILNYFPALLNYGANVLFqdgkyMNNEQIGELVKLIIKIYKFVSYHDLPFTLQRSESFTPW 240  baker's yeast
19074671  143 RVFDAEKIKYNLEQVLGLMFDTAGKDILEKVYGFLES------GNYGMVKTGMIVLS--KSYCYYSIPDFLSAIGTFSYV 214  Encephalitozoon c...
19075603  150 ELAKVYRWRLDDRQRDIGPLVAALFPTILQLGQGLINl----EDND-SAEMLRLILKTFKSVIALELPPELLANDMILSW 224  fission yeast
6320603   149 QLCKAHRWDMVGSRDYIDSVIEELFPIVEGIASNIGS-----QTDYRSNEILYLILKSFKYACLNNLPQYFSQPERIMSW 223  baker's yeast
1171739   241 ACFFVSIIQQPLPQEVLSIsDIEVRSKNPWVKCKKWALANLYRLFQRYASTSLTRk---fQYDEFKQMYCEeFLTQFLQV 317  baker's yeast
19074671  215 FNLSLRILNLEGSNEDLLE--------S-----KKWAAYFMYKSCSKGIKKFYKK-----SELSEYITDMN-RFQMVYAT 275  Encephalitozoon c...
19075603  225 IQLLLAVVQKPLPESLMSL-EPEVRQSHVWHKCKKWAYYSLNRIFTRYGEPSSLVgdsanKYRAFAKNFITnVVPNILET 303  fission yeast
6320603   224 VQLHLYLCSKPLPVEVMEL-DPADRSLDKRVKVNKWGFGNLNRFLQRYNKITKAI-----TKEFIDYIFNT-IVPIILRE 296  baker's yeast
1171739   318 VFDQIEKWGTGQLWLSDECLYYILNFVEQCVVQKTTWKLVGPHYNVILQHVIFPLLKPTAETLEAFDNDPQEYINRNMDF 397  baker's yeast
19074671  276 FLKIIQERSQ-Q--TIDIELYAIDFFVLLTSDAD-FFRYMEPNLSYFISGYILPLYSLSDSEEDDFENDPDKYLREKYNF 351  Encephalitozoon c...
19075603  304 YIQQTILWTQGQLWLSPRVLYFLGCFYEECVKPKSTWALLKPHLQLLIGSFVFPQLCMSEEDEELWELDPVEFIHKYIDI 383  fission yeast
6320603   297 FFKDIEAWGNNSLWLSDSSLYFLISFLEKCVTIDQLYPLIEPHLQIIFENVIFPCLCANEQSIELLEDDQEEYTRRYFDI 376  baker's yeast
1171739   398 WDVGYSPDLAALALLTTCVTKRGKTTLQPTLEFMVSTL-QSAVGDYNnimLDNALQIESCLRIFSSIIDrLITKDSPFAS 476  baker's yeast
19074671  352 FGNGLRSSLNTLFCEIISKVKQKEETFQGIISYLLSILgGSKETPSR----DNIRAAYGSFFLLASIKS---TLMKKARN 424  Encephalitozoon c...
19075603  384 YDDFNSADVAASRFLVKLASKRKKYTFMGILSFASDILnQYAASPPN---EKNPRQKEGALRMVAAVSNsILSKNSPVAG 460  fission yeast
6320603   377 NREGSTPDAASADFIFLIGSKRPEK-LNNILPFINDIFtRFDANSSD---INMAFKEEGALRTLSNLFS-FIDEPSVLEN 451  baker's yeast
1171739   477 EMEKFILTYVLPFFKSQYGFLQSRVCDICSKLgSMDFKDPVITSTIYEGVMNCLNNssNSLPVELTAALALQTFISDD-Q 555  baker's yeast
19074671  425 VLEYIVANHVIPALRGNSCILKSQACYFLSTI-EEDLPINGLALEALDNTHKLMKS--SHRALMVESTLAMSFFLFNE-A 500  Encephalitozoon c...
19075603  461 MMQDFLVAHVMPEFTSPVGYLRSRACEMINRFsEIDWSDKSQLLNAYQAVLNCLQD--NDLPVRIQAALALQPLMRHL-E 537  fission yeast
6320603   452 IFGHFIVPLLS---QDKYMFLVARSLETIALY-SEEFKDMNILSQLFELTYTNFLNs-NVLPVQIEAADAIKCLIVSNpQ 526  baker's yeast
1171739   556 FNMKLSEHVVPTMQKLLSLSNDFESDVISGVMQDFVEQFAEQLQPFGVELMNTLVQQFLKLAIDLHETSnldPDSFTNVD 635  baker's yeast
19074671  501 SSEKFRQLIPETVESILSLSNTYNLEPLTMLLDSIIGYYPEEISKYAPELVGSISR----ITLSHLMNE------SDVGE 570  Encephalitozoon c...
19075603  538 VHDVMTAHVPIIMQNLLFLANEVDIDALSSCMEEFVSSFSHELTPFASQLAKQLRNTFVKLMQETMDESttvDDFDSLVD 617  fission yeast
6320603   527 IHPAVSAHVPGMMEKLLKLSKIFEIDILSEVMEALVERFSDELSPFAKDLASNLVEQFLRIAQALVENP---SETYSASD 603  baker's yeast
1171739   636 sipdesDKQMAALGILSTTISILLSFENSPEILKNLEQSFYPAAEFILKNDIEDFYRECCEFVENSTFLLRDIT-PISWK 714  baker's yeast
19074671  571 ------DKQMVVSGFLRSIESLILSLDQRSLVLKYSYVNSYDVISFILKEEKSDFYQEALDILNGYVYMIKEIE-GSMWG 643  Encephalitozoon c...
19075603  618 ------DKSIAAIGILNTLSTMILSLENTVDVLREIEAILLPMINFVLDNNIFDVYAELFEIIDGCTFASKEIS-PIMWG 690  fission yeast
6320603   604 q-----EQEIQASGLLQTMTTMVMSMNKVP-----LIESLAPVVKFVVLHAQISFITEAVDLLDALTISSHLLYnQIAPP 673  baker's yeast
1171739   715 ILELIGECNRKPDSmVsYYLSDFMLALNNILIYGRNELKKNEFYTKIIFEIYQKAVTAEDNSL-DDLRVVFDLSQELVLA 793  baker's yeast
19074671  644 LFQMVLNLPIDEIT---VYSTEVADLIDNFITYGKTSVMDAGILGSICSVISKLCLCNEENFLdEDFIGGCRIIESIILN 720  Encephalitozoon c...
19075603  691 VYEKLQKVLKESG--I-EFVEEATPALSNFITYGGKEFASRPDYIAVMVDIIMQVFNSEHLAV-NDRVSACKLTELLMLN 766  fission yeast
6320603   674 IWELLHDILDSFQTyAmDYFEAYSIFFETIVMTG---FPQDQTYVQPLLEILSAKLESEVD---YDIEHVMQILMYFALS 747  baker's yeast
1171739   794 LDDSLPQQ---YRErLLADVVGSILTQKNELKtnvVFSVTAFNVVISNMITEPLITLQYLKQQGCLEIFFQTWITDyIPN 870  baker's yeast
19074671  721 IGNELLSKdpsRLP-LFISVAISGEKMIDEDG---PAIVYALELIMNCFILRPKETIRILREQKYLQSFFEKLFSQ-KNK 795  Encephalitozoon c...
19075603  767 YRG-LLDQ---YVP-AFIEVAG-NLLLVTEKPtsqTYRVFLLEVIINALYYNPSMSLGVLEMHQWTLPFFALWFEN-IPS 839  fission yeast
6320603   748 MRD---------IP-LFSKAIK--VSTNDELG---LDSKCIVKLGLANLFAKPIETLQIMENEGFTINFFTNWFNE---K 809  baker's yeast
1171739   871 YKRCYDIKLSVLALLKIILKLesndYSVLNLENLVPQLGSIVTQLASRLPTALRQLAnqrKEFSSSGFEEDtkwdenfld 950  baker's yeast
19074671  796 FKRVHDKKICMLFIGTICRLQ-----DGALPELDVHGLGEVLVATVTSLPEAIRLRN---QMKDDEDAPPP--------- 858  Encephalitozoon c...
19075603  840 FTRVHDKKLSLVAILSVISLGa--qQVAVAIQDSWGNIMKVMITLLNTLPEALAARAeleKEYDGETFNLSgsgwndgid 917  fission yeast
6320603   810 FYSVFAIKLQVLVILTLLKMP----EVPNSVSPLLNNLTNKLVELTLSLPKAIRNRD----AVTEGKSLEG--------- 872  baker's yeast
1171739   951 vgdddenddegDLTEKYLEliknradsldFVDGYDAKETFDd---LEEDPLTGSILDTVDVYKVFKESIANLQHVDSNRY 1027 baker's yeast
19074671  859 -----------LVNTEDDQ----------CLDASDISCTDI----LEEDIYFETELDKFEPFGYISSILS--SPASGTYA 911  Encephalitozoon c...
19075603  918 w-eadddegvdDFAVEYGGpdlggeisadVVDDFDEFEHFQgnylLDEDPLFHTLLDQVDPFSLFQEFMVHLKDNSPVTL 996  fission yeast
6320603   873 -----------DLTPEEEE------------------EYFI----ECDDDMKETVLDQINVFQEVHTFFKNLQNEDAGKY 919  baker's yeast
1171739  1028 QGILRHLTPADQELFMGIMNA 1048 baker's yeast
19074671  912 EKIISTMTDEQKDSLSTVLNG 932  Encephalitozoon cuniculi
19075603  997 QDLVKNLEASEQQSLQRLVTE 1017 fission yeast
6320603   920 EKIINYLDESKRDSLQVILEF 940  baker's yeast
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