416589 5 KPNAVrtfrqvqhcsfricryQSTKsnkclTPLQEYDRLVKLGKLRD--------DTYQRGIISSLGDLYDslvKYVPPV 76 baker's yeast 16127761 1 MPT---------------------------SLRTAYRERLAQGEIRP--------DVAQAAAVEALSRLEA---DLDAAG 42 Caulobacter crescen... 15805785 1 ---MTrsvshpp--yadpfahPPET-----SPQELTAQLTPGARFQDvrfenyrpNPEFPSQAQARDQLAEfvrQAGQKA 70 Deinococcus radiodu... 15842208 10 SATMHgsaseacgsvdhlvdrHPTV-----SPVRLIAQLRPPPTFAEvsfatyrpDPVEPTQAAAVVACQDfcrQAVERR 84 Mycobacterium tuber... 15597549 1 MPDTSp--------------dLPAM-----SPLAVYRQAVEQRGFAP--------DEAQRRAAEALERCFQ------ALH 47 Pseudomonas aerugin... 15599735 3 FGSFSwr------------spMTGTkp--tTPVARYFHQEAQRRGYVl-------DAAQGNAILHLDRLAE--------R 53 Pseudomonas aerugin... 15892205 1 -------------------------------------MIKSSTSLIQ--------DSKQTALREELKQLAA---ALNKPK 32 Rickettsia conorii 15604083 1 -------------------------------------MIKCLNSFIL--------DSKQTALLTELKELAK---EVNKSK 32 Rickettsia prowazekii 15966810 3 NPDd--------------------------SILHKLEALVAAGERQR--------DPAQFAIARRLDSLTA---NLLASR 45 Sinorhizobium meliloti 19112051 9 APCFAfvdtigsigvcrvvrfTTFHn----TPIEVYNKKVNDGVWKR--------DPYQETAVKAINRLYTeleSYTQPP 76 fission yeast
416589 77 VKTPnavdqv---ggwlnGLKSVFSRgkpknigayvdvskiGNSIPRGVYLYGDVGCGKTMLMDLFYTTIPNHLt-KKRI 152 baker's yeast 16127761 43 EPGFs-----------------FFGRkp------------kSQ---RGVYLWGPVGRGKSMVMDLFFDSAPVAK--KRRI 88 Caulobacter crescen... 15805785 71 SGGG----------------FWPFKR---------------RAPEGRGFYLDGGFGVGKTHLLASAYHAAKGQS--GGSG 117 Deinococcus radiodu... 15842208 85 AGRK----------------KWFGKR---------------DVLPGVGLYLDGGFGVGKTHLLASAYYQLPG-T--GPDA 130 Mycobacterium tuber... 15597549 48 EAHR--------------------------------------HGAIQGVYLWGPVGRGKTWLMDHFYQCLRVPA---RRQ 86 Pseudomonas aerugin... 15599735 54 LRRG----------------PSLFRQ------------------APRSLYLWGPVGRGKSWLMDGFFRSADLQG--LRRT 97 Pseudomonas aerugin... 15892205 33 SLFK------------------FFNQ----------------NNLESGIYLYGPVGSGKTMLMNSFCEELTTPK---III 75 Rickettsia conorii 15604083 33 SLFK------------------LFNK----------------HHLKNGIYLYGPVGSGKTLLMNSFFDAISISK---TIL 75 Rickettsia prowazekii 15966810 46 PSRKt------------nALGWLFAArk------------kDQPPVKGLYIHGGVGRGKTMLMDMFFDAVPIQR--KRRA 99 Sinorhizobium meliloti 19112051 77 ITQDsmpaekgsilswisPLKKMFSRkksptl----tsslpVPGMPKGIYLYGDVGCGKTALMDLFYHNLPPNVtrSQRI 152 fission yeast
416589 153 HFHQFMQYVHKRSHEIVreqn---lkelGDAkgkeiDTVPFLAAEIANNSHVLCFDEFQVTDVADAMILRRLMTALLSDd 229 baker's yeast 16127761 89 HFHAFMAEVHADIDVWRkgdaatrkarfGQSkg--dDPVAPTADRIAGEARLLCFDELQVTDIADAMILGRLFEALFAR- 165 Caulobacter crescen... 15805785 118 G--DVAFMSFQDLMYLIg------------------ALGMPQAIETFRNYKLLLIDEFELDDPGNTHMANTFLGGLMPS- 176 Deinococcus radiodu... 15842208 131 PTCPKAFATFGELTQLAg------------------VFGFADCIDLLANYTALCIDEFELDDPGNTTLISRLLSALVER- 191 Mycobacterium tuber... 15597549 87 HFHHFMQWVHQRQFELT-----------GTA-----DPLRALARELARDVRVLCFDELFVSDIGDAILLGSLLRIMFEE- 149 Pseudomonas aerugin... 15599735 98 HFHAFFRRLHDGMFRRQ-----------GRP-----DALGGALDELLGDCRLLCFDEFHVHDIGDAMLITRLFRELFGR- 160 Pseudomonas aerugin... 15892205 76 HYQNFMQEIHKSMHKLQt---------aNQK-----DIIPKIAKNYTKQTKVLCIDEFEIKDITDAMIIGRLFNELIKQ- 140 Rickettsia conorii 15604083 76 HYQNFIHEMHKSMHRLQt---------eKQK-----DIITKIAKNYAKQTKVLCIDEFEIKDITDAMIISRLFNELIKQ- 140 Rickettsia prowazekii 15966810 100 HFHEFMADVHERIYRHRqkl------knGETkq--aDPIPPVASDLFGEARLLCFDEFTVTDIADAMILARLFGELFAK- 170 Sinorhizobium meliloti 19112051 153 HFHAFMMQVHRTSHDLQdr--------yGFEi----DFIDHIASGIAKETTVLCFDELQVTDVADALLLRRLFEALMKY- 219 fission yeast
416589 230 yGVVLFATSNRHPDELYINGVQRQSFIPCIELIKHRTKVIFLNSPTDYRKIPRPVSS--VYYFPSDTsikyaskecktRR 307 baker's yeast 16127761 166 -GVTLVATSNRPPEDLYKDGLNRQLFLPFIDMLKSALDVVAVRGPVDFRLDRLRAAR--TWLAPNDK-----------AS 231 Caulobacter crescen... 15805785 177 -GVSVVATSNTEPGALGAGRFNAEDFQRQIQGIADRFGPHRIDGP-DYRQRGTEPA------------------------ 230 Deinococcus radiodu... 15842208 192 -GVSVAATSNTLPEQLGEGRFAAQDFLREINTLASIFTTVRIEGP-DYRHRDLPPAP----------------------- 246 Mycobacterium tuber... 15597549 150 -GVVLVATSNQPPEQLYADGFNRERFLPAIEAIQRHMAVVAVDGGQDHRLHPGRAEQr-YWVVEAGQ-----------AS 216 Pseudomonas aerugin... 15599735 161 -KITLVCTSNYAPRQLLPNPLYHERFLPAIRLIETRMEVLEVAGARDYRTISPRQEIasGYASGGYCw---------pAS 230 Pseudomonas aerugin... 15892205 141 -NIFIFITSNTSPNNLYKDGLQRESFLPFIKIINNTFYVKYLDNQHDYRFDKALRVKeaRIIYPLTL-----------EN 208 Rickettsia conorii 15604083 141 -NIFIFITSNTSPNNLYKDGLQRESFLPFIKTINNTFYIKYLDNHHDYRFDKALGVKssRIIYPLTL-----------EN 208 Rickettsia prowazekii 15966810 171 -GCVLVATSNVEPDNLYRDGLNRGLFLPFIDLLKANAEIISLDTETDYRLGKTDGAP--VWLSPLGP-----------ET 236 Sinorhizobium meliloti 19112051 220 -GVVIFITSNRAPSDLYKNGIQRESFIPCIKLLEHRLQVICLDSPNDYRRLKSKTED--TYLYPANSp----------EV 286 fission yeast
416589 308 ETHIKEWYNYFAQasHTDDSTDshtvhktfydyPLTIWGREFKVPkCTPPRVAQFTFKQLCGEPLAAGDYLTLAKNFEAF 387 baker's yeast 16127761 232 QAAFDGLWTDMLD--GAPETGA-----------TLEVLGRKMRLP-RAAGGLVRSSFASLCQQALGPQDYLAIAERFHTL 297 Caulobacter crescen... 15805785 231 --------QPLSE--A--EFAA-----------WLARQ------N-PQTTALMTHAELNRALLSVHPSRFARVLEQVSGV 280 Deinococcus radiodu... 15842208 247 --------APLSD--E--EVAA-----------RAAR---------VEGATLDDFDALCAHLATMHPSRYLTLIEGVTAV 294 Mycobacterium tuber... 15597549 217 G--FAELFARLSA--GEAASTQ-----------PIELGHRPLAVH-RHSESVLWCSYAQLCEAPLSALDFIGLCDRYRAI 280 Pseudomonas aerugin... 15599735 231 CACLDELGLSAPE---PSQRVT------------LQSGARTLQAR-AVCGDLVWFAFADLCEAPTAVMDYLALGERFSTW 294 Pseudomonas aerugin... 15892205 209 QNKLEKIITDISD---NNLAPQ-----------NIQVLGREISFQ-KVHKRILVTDYNELFTRGLSYIDYVNICQNFNVI 273 Rickettsia conorii 15604083 209 KNKLKKIIMKISD---NNLVAQ-----------NIQVLCRSISFQ-KVYKQILVTDYNELFIRELSYIDYVNICQNFNII 273 Rickettsia prowazekii 15966810 237 EAAMDRAWYRETS--GAPAASA-----------EIGRKGRTIRVP-AAAGRAARFTFADLCAQPLGAADYLAIVAQYSTI 302 Sinorhizobium meliloti 19112051 287 KKALENWFLCYADe-KDPAHQD-----------EVEVFGRKIIVP-KASGNVAWFTFEQLCGEPKSAADYLSLASRYHVF 353 fission yeast
416589 388 IVTDIPYLSIY-----------------------------VRDEVRRFITFLDAVYDSGGKLATTGAADFSSLFVEPEQi 438 baker's yeast 16127761 298 FLEDVPCLTPA-----------------------------RRDAARRFNTLVDALYEADVKLVALAEAEPEQLYPEGEG- 347 Caulobacter crescen... 15805785 281 AVTNLEPMP-------------------------------EQGEALRFVHFVDKVYDLGLSAAFTG-VPLNALFDDIYR- 327 Deinococcus radiodu... 15842208 295 FLTGVHGID-------------------------------DQNVALRLVALVDRLYDAGIPVVASG-AKLDTIFSEEML- 341 Mycobacterium tuber... 15597549 281 LMDDLPCLSASqregriargtedgaqlveagdrelpqlsvHDDGVRRFIALVDECYDRKVPLYLEARVPLEALYTEGYL- 359 Pseudomonas aerugin... 15599735 295 VLEGVPPMARC-----------------------------SVAAQQRFINLVDVLYDNDRRFFLSAEKALPDLVEGSDL- 344 Pseudomonas aerugin... 15892205 274 IVGNVHTIDSN-----------------------------DTNTAVRFINFIDNAYFYKILLFMSLEDNPNKIYQGSAR- 323 Rickettsia conorii 15604083 274 IVENINTIDAN-----------------------------DTDTVVRFINFIDNAYFYKILLFMSLVDNPNKIYQGLAR- 323 Rickettsia prowazekii 15966810 303 FLDHVPHLGPH-----------------------------LRNETKRFIILVDALYDQGARLFASAAAEPQHLLTARKGt 353 Sinorhizobium meliloti 19112051 354 IVSDIPKLSIE-----------------------------SKDLIHRFITFIDALYDTHGKLILSSEVPVQEIYPTAPSe 404 fission yeast
416589 439 lndfelrpttkepdsvdtgmvdemvekhgfskeiakksqmfaldeeRFAFARALSRLSQMSSTDWVT-KPTY 509 baker's yeast 16127761 348 ----------------------------------------------AFEFERTVSRLQEMRSADYVGrVRD- 372 Caulobacter crescentus CB15 15805785 328 ----------------------------------------------NGGYAKKYSRALSRLSEMLR---EAR 350 Deinococcus radiodurans 15842208 342 ----------------------------------------------AGGYRKKYLRATSRLLALTAGvIQAR 367 Mycobacterium tuberculosis ... 15597549 360 ----------------------------------------------AFAFRRTLSRLREMQLARFGS--DSA 383 Pseudomonas aeruginosa PA01 15599735 345 ----------------------------------------------PADMQRTASRLAQLRQLRC------- 363 Pseudomonas aeruginosa PA01 15892205 324 ----------------------------------------------AAEFKRTISRLNEMNSESYLLnNDFK 349 Rickettsia conorii 15604083 324 ----------------------------------------------AKEFQRAISRLHEMNSEAYLLnNDLK 349 Rickettsia prowazekii 15966810 354 ---------------------------------------------eGFEFDRTVSRLIEMQSQEYAAaHPQN 380 Sinorhizobium meliloti 19112051 405 vlsstadpaakgk-------------------ieshyhgafggieeVFTFTRCLSRLSEMKKQSWIH-SP-- 454 fission yeast
Jiyao W et al.(2023). "The conserved domain database in 2023.",