549739 64 PRIEKSNRFKVFPGLLLGICLSFFLNYLVHAfaseslvhcadsgdhatgshihsksHShSHSHSHADSHSNFSNDHDleN 143 baker's yeast 14600527 1 MYLMNPAITPILLGLVAGITVTFGALTYIVVg-------------------------R-RLGRRGQGVLNALAGGVL--A 52 Aeropyrum pernix 15839705 1 -------MFKRARAEIFDRNREVGISNVTTAa------------------------SL-VTFPVLAGILGGVVPSVR--T 46 Mycobacterium tuber... 18312037 1 ----MENLIPLLYGFLAGVTVLIGAVAMYKAr-------------------------E-KLKPGHLGVLQAIAGGIL--A 48 Pyrobaculum aerophilum 18313478 1 MIFIKEPLFFLFVYFLFFPLLRVGTRPYVY-----------------------------AIAGGAAAHMALMAGGNA--S 49 Pyrobaculum aerophilum 15607459 1 -MSLAVTMFKRARAEIFDRNREVGISNVTTAa------------------------SL-VTFPVLAGILGGVVPSVR--T 52 Mycobacterium tuber... 19115854 64 LLSSSKTLAELSKGELAKAREDLKSVLSFLKnnlpvdtessse--aftiekdnnscVWlNSVKSFVEKQFSYSSGTNg-I 140 fission yeast 15899777 1 -----MNYFPILLGLIAGGTVAIGAIIISKG----------------------------KFNKTTIGYLGAFTGGIL--S 45 Sulfolobus solfatar... 15790671 1 MSVSHSTSSARARTIRLGAASAIAFLALSAYv-----------------------sRTgDAPKLVGISWVAFTAMAGaaA 57 Halobacterium sp. N... 731788 34 HESKQSFLILKQESIFYSLVCFLQNHLFVLGpry-------------------naiVAiLIIQLMPCLFVLFVPGLRknD 94 baker's yeast
549739 144 APSEHGYATSSSSVSENDPLITKDSdr---pqMKKKMSlidlltrrksegeccdlnkctpllqseqpeyiaCVPPVIKSS 220 baker's yeast 14600527 53 YLALETG---HESAAYVEQFATRET-------LDSFLAg-------------------------------lMVTSIALLG 91 Aeropyrum pernix 15839705 47 PSAAMVSGVQHFAAGIVMAAVAGEV-------LPDLRSrg-----------------------------plWLIVVGFSA 90 Mycobacterium tuber... 18312037 49 YLALETR---HGAAEYVESLAKPET-------FPDFVTa-------------------------------sIITTAAFVI 87 Pyrobaculum aerophilum 18313478 50 SLPKSLAVAWPVNLIP-------------------------------------------------------LFLYAVIIT 74 Pyrobaculum aerophilum 15607459 53 PSAAMVSGVQHFAAGIVMAAVAGEV-------LPDLRSrg-----------------------------plWLIVVGFSA 96 Mycobacterium tuber... 19115854 141 LATFLTAIPPNIFILLVPKSFDTSMln---lfVAVSAGsllgdvflqllptvy----stnggdfpassvysILIGALVFF 213 fission yeast 15899777 46 YLALDTG---SEAEEIVTNFLAVKD-------YPDFTVa-------------------------------lILTSIGLIG 84 Sulfolobus solfatar... 15790671 58 LGGHTTADHPRGLVWGYGLASGAMIasaaaflLPQAIG---------------------------------YAAKPGGFG 104 Halobacterium sp. N... 731788 95 RASLTLSLLVSFSLGTLLGDILLHVip---esLSGVTDvtmv--------------------------ggaIFLGFISFL 145 baker's yeast
549739 221 QSERNVPhgcegsedngqsddKDHRGlvcvennigydlenlslyrknflssrhhhssespenygsnqlshsfSSPLGNDV 300 baker's yeast 14600527 92 TWLLLSY--------------VERGY----------------------------------------------S--T--LV 107 Aeropyrum pernix 15839705 91 GVAVLVA--------------LRRFD----------------------------------------------G--HGEHQ 108 Mycobacterium tuber... 18312037 88 TFLALAK--------------GER-L----------------------------------------------G--L--RA 102 Pyrobaculum aerophilum 18313478 75 SAAFLVF---------------LRAG-----------------------------------------------------T 86 Pyrobaculum aerophilum 15607459 97 GVAVLVA--------------LRRFD----------------------------------------------G--HGEHQ 114 Mycobacterium tuber... 19115854 214 LMDKGIRil-----------iHERPSslskpkkdgeet----------------------ssvnkpsasstqTDVKGVEG 260 fission yeast 15899777 85 TWLLLSL--------------LEK-------------------------------------------------------- 94 Sulfolobus solfatar... 15790671 105 VAAGILTg------------fGAHTIg------------------------------------------------HRLSH 124 Halobacterium sp. N... 731788 146 TLDKTMRilsgts--nddgsiHSHSHs--------------------------------------------hTPQQTAEK 179 baker's yeast
549739 301 TENPAaladtqyhpengslyphhhhletpfsklLSIGMQTCLVLALHKFPEGFIIFYTNRSDSSksLGFSIFLSLTIHNF 380 baker's yeast 14600527 108 RAPPG----------------------------LMVSLTVASALGLHNLGEGLAIAASLIEGKVs-LAILFAVGFAIHNY 158 Aeropyrum pernix 15839705 109 DGDDV----------------------------GELPVGFLTVVAVDLFIDGLLVATGATVSSR--TAIIITIALTVEVL 158 Mycobacterium tuber... 18312037 103 GMSPT----------------------------YATAFVIALALGVHNVGEGFAIAASLLAGALa-SAVLFTMGFAIHNA 153 Pyrobaculum aerophilum 18313478 87 KVSP--------------------------------GDALALGLGLYNYSYGLMIASAVYSLPRy-SELAEPLLLSGLIT 133 Pyrobaculum aerophilum 15607459 115 DGDDV----------------------------GELPVGFLTVVAVDLFIDGLLVATGATVSSR--TAIIITIALTVEVL 164 Mycobacterium tuber... 19115854 261 LRKRNvkddqnskghepdlirhvveevseeyndKTVVYLNLLCDSFHNFMDGLAITSAFFTNTS--IGISTTFAVLLHEI 338 fission yeast 15899777 95 -NPSG----------------------------EGLPVVVASALGFHNIGEGFAIAAALLSGSVa-AAWAFTIGFAVHNA 144 Sulfolobus solfatar... 15790671 125 LDLP--------------------------------LDRTTAELSAHSLAAGSIIGVVYTAMPG--LGPLLGLAIVSHKG 170 Halobacterium sp. N... 731788 180 KAGFN-----------------------------MSAYLNVISGIAHHITDGIALATSFYSSTQ--VGIMTSIAVTFHEI 228 baker's yeast
549739 381 VEGFAMTLPFYTVFe-SKWVAILITAVLGGGSQPLGALIGYFIFKGSTpr-----dhEPNMDFLLSVTAGFLLVIGLQMF 454 baker's yeast 14600527 159 TEGFPIAAPLAGEKk-RTGLRTIIGLSLLAGLPVVPGAM-VYYLGSNLp--------GLAIATLYTVAAASIVYAMLHIN 228 Aeropyrum pernix 15839705 159 FLGLAVALRLAGSG--MPRIRAAATTSALSLVIAVGGVSGAVALGRAG---------NTVLTLVLAFAAAALLWLVVEEL 227 Mycobacterium tuber... 18312037 154 TEGFAIVGPLLGDRnaRPSLTYITALSMLAGLPVIPGVA-VYYAGFNN---------ALFIAVLNTVANASIVYALLHVN 223 Pyrobaculum aerophilum 18313478 134 FAGVEVFVLRAVASstKSALKTWPVPAITFPAGWLSYWVLPPLSTDIYp--------RLILATAQAGSAALIVYAMFRNN 205 Pyrobaculum aerophilum 15607459 165 FLGLAVALRLAGSG--MPRIRAAATTSALSLVIAVGGVSGAVALGRAG---------NTVLTLVLAFAAGALLWLVVEEL 233 Mycobacterium tuber... 19115854 339 PAEIGDLAILLRNG--YTKSQVLVLQMITMVTGLLGAIVATYIYTASSssspygsflLQLEDKLLPFTAGGFLYIAYLGV 416 fission yeast 15899777 145 TEGFAISSPAVMSKr-VMGLKVLIPLSLLAGLPTTLGAS-IYYLGISN---------EIFLAFLNVVASASLVFVMIRIN 213 Sulfolobus solfatar... 15790671 171 PAGYAAARRLARTD--RSPAMLLLPAAGVGIAALAVTVVSFPTAPVFRavvf-gfaaGIFLHVAMDFLPHCETGSDVHDA 247 Halobacterium sp. N... 731788 229 PHELGDFAILLSSG--FTFPQAIRAQAVTAFGAVVGTSIGCWMNEIGNnshkatsssANASELMLPFTAGGLIYIATTSV 306 baker's yeast
549739 455 QTGIGFSDghhhhqGEGDEEMKQSHSSGTTCLKWCCTGVLL 495 baker's yeast 14600527 229 LSALSRLG------GLSSPSFWSSLFLGIALAYVTESIILI 263 Aeropyrum pernix 15839705 228 LVEAHETP--------ERPWMAVMFFAGFLILYGLGVME-- 258 Mycobacterium tuberculosis CDC1551 18312037 224 LNALSKLG------GLTSYKFWASLTAGVAIAFSTESILLF 258 Pyrobaculum aerophilum 18313478 206 LVAASLMG------GLSSYKFWASLFGGVMLYAVPEVLIHL 240 Pyrobaculum aerophilum 15607459 234 LVEAHETP--------ERPWMAVMFFAGFLILYGLGVME-- 264 Mycobacterium tuberculosis H37Rv 19115854 417 FPELLEIN------LSKGKLGNMIYTALYMMFIVGGFSFLY 451 fission yeast 15899777 214 INAASLLG------GFKAR-FWTWLFIGIATTYGLEVLLDI 247 Sulfolobus solfataricus 15790671 248 VTRSAHDHdha-llDRLRLHAVASTGLGAAVVAAAWVLLQ- 286 Halobacterium sp. NRC-1 731788 307 VPQILHSSa-----PDSKLREFKKWALQLVFIFVGFAVMAL 342 baker's yeast
Jiyao W et al.(2023). "The conserved domain database in 2023.",