2QLV,2OOX


Conserved Protein Domain Family
AMPKBI
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smart01010: AMPKBI 
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5'-AMP-activated protein kinase beta subunit, interation domain
This region is found in the beta subunit of the 5'-AMP-activated protein kinase complex, and its yeast homologues Sip1, Sip2 and Gal83, which are found in the SNF1 kinase complex. This region is sufficient for interaction of this subunit with the kinase complex, but is not solely responsible for the interaction, and the interaction partner is not known. The isoamylase N-terminal domain is sometimes found in proteins belonging to this family.
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Statistics
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PSSM-Id: 214973
Aligned: 33 rows
Threshold Bit Score: 85.8344
Created: 12-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2QLV_B       139 PRPPLEYTTDIPAVFtdpsvmeryyytldrqqsnTDTSWLTPPQLPPQL-ENVILNkyyaTQdQFNEN------------ 205 baker's yeast
NP_510298    180 LEKLHQFGQETPtr-------------------vDFNKAAAPPVLPPHL-LQVILN----KD-TPVQC------------ 222 nematode
XP_003104072 192 LEKLRSFTQEIPSMd-------------------MLRKAAGPPVIPPQL-MQVLLN-----KeTPESC------------ 234 Caenorhabditis ...
XP_002129192 167 TSPNESYTQDVPRSLl-------------------EDSSLHPPTLPPHLlNKVLLN----QDiDMSYE------------ 211 Ciona intestinalis
XP_640809    250 STPPGSYSRTIPe--------------------eEVQKIP-PPSLPPHL-RRALLNt------QPSTE------------ 289 Dictyostelium d...
Q9SCY5       198 QSPENSYSNLLl---------------------gAEDYSKEPPVVPPHL-QMTLLN----Lp-AANPD------------ 238 thale cress
CBH13243     181 TRANVIHVNKALLLTkedeevpddgsgwgqeeiiHKEDRKHPPIMPVHL-RYTPVN----TPlTAARCaldgfmr----- 250 Trypanosoma bru...
XP_001465729 198 KPANTIFLNDVLLTTkedddimdngegwgqepimFEESRKYPPIVPLHL-RYTPLN----TPpTLVRCsrdgrmavmdag 272 Leishmania infa...
NP_197615    196 PSPDHSYGQTLPA---------------------AEDYAKEPLAVPPQL-HLTLL---------GTTE------------ 232 thale cress
NP_565664     21 VSPVSSYNNvy---------------------ssTEDETRDPPAVPPHL-QHSLL---------GNQG------------ 57  thale cress

2QLV_B       206 -------NSGALPIPNHVVLNHLVTSSI--K--HNTLCVASIVRYKQKYVTQILYTPI 252 baker's yeast
NP_510298    223 -------DPNVLPEPDHVMLNHLYALSI--K--DGVMVLSATHRYRKKFVTTLLYKPI 269 nematode
XP_003104072 235 -------DPNVLPEPNHVMLNHMYALSI--K--DSVMVLSSTQRYRKKFVTTLLYKPV 281 Caenorhabditis remanei
XP_002129192 212 --------PSLLPEPPHVTLNHMYALSI--K--DGVMALSATHRYKKKFVTTLLYKPI 257 Ciona intestinalis
XP_640809    290 -------DPTLLPLPHHVMLNHLYSLPR--K--NKVSILGVTHRYKTKFVTTVLYKPn 336 Dictyostelium discoideum AX4
Q9SCY5       239 -------IPSPLPRPQHVILNHLYMQKG--KsgPSVVALGSTHRFLAKYVTVVLYKSL 287 thale cress
CBH13243     251 ttdedtvSPENLPIPLSVTVNHVYFQ-R--R--EDHCVTAMTTRFCNKYSTMVYYSKA 303 Trypanosoma brucei gambiense DAL972
XP_001465729 273 aehssrvPPEHLPLPLSVTINHVYFQ-R--R--EDHAVMGVTTRYCNKYTTVVYYSHL 325 Leishmania infantum JPCM5
NP_197615    233 -------ETAIATKPQHVVLNHVFIEQGwtP--QSIVALGLTHRFESKYITVVLYKPL 281 thale cress
NP_565664     58 -------SMELAYAPQNVVLNHLYIENRdaP--RSVVALGFSHRFRTKFVTVVIYKPV 106 thale cress
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