2CXH


Conserved Protein Domain Family
Brix

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smart00879: Brix 
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The Brix domain is found in a number of eukaryotic proteins.
Members include SSF proteins from yeast and humans, Arabidopsis thaliana Peter Pan-like protein and several hypothetical proteins.
Statistics
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PSSM-Id: 214879
Aligned: 150 rows
Threshold Bit Score: 55.4331
Created: 13-Jul-2011
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2CXH_A        37 LVTTSRRPSPRIRSFVKDLSATIPGAF---RFTRGHYSXEELAREAIIR--GADRIVVVGEr--rGNPGIIRVYAVegPE 109 Aeropyrum perni...
XP_001349334  51 MVIKKKGMNSEIKALSRDLVDLFNPYCavfYIRKLKNLQELNKKLKELS--YKYTVCFYIQnnklLYSITSNYTKL---- 124 Plasmodium falc...
XP_765007     36 LVIRRGSvnHEIKQLAQNLRLILSPNC---AVRLKEGSRQRLRDFTSVTdvLGLTHLIVLSq--gSESSYLKIANL--PS 108 Theileria parva...
XP_843876     24 IIIYRGEvGGSVRSLMHDWRAVFLPWS---SKKLR-GENRSLKDFLVIAssLSVSHLQLFTapsyG--TSLRIMRF--SN 95  Trypanosoma bru...
XP_001462818  28 IIIYRGDvGVHVRSLMHEWRNVFLPWS---SKKLH-GKNKSLKDFLAVAatFSASHLQLFTapsqG--TSLRIMRF--FN 99  Leishmania infa...
NP_001191384  30 FVFPRGHvGSNVQQLAMDMRRVMEPFT---ASKLKVRKKNVLKDFVAVAgpLGVTHFISFSkttsG--VNMRLARL--PK 102 Ciona intestinalis
NP_001191417  31 FVFQRGQiGKNVQQLIVDVRRAMEPFT---ARSLKVRKKNTLKDFVAVAgpLGVTHFMIFTktttN--VNFKFVRL--PK 103 western clawed ...
NP_001191389  32 FVFSRGAvGKTIRQLSLDLRRVMEPYT---ASALQVRKKNSLKDCVAVAgpLGVTHFLIFTktenN--IHLKLVRL--PG 104 platypus
NP_001191381  32 FVFARGPaGPGVRQLSLDVRRVMEPYT---ASSLQVRRRNSLKDCVAVAgpLGVSHFLIFSktekN--VTFRLIRL--PG 104 gray short-tail...
NP_001191368  32 fvfargragrgVRQLSLDLRRVMEPLT---ATRLQIRKKNTLKDCVAVAgpLGVTHFLILSktetN--IYFKLMRL--PG 104 dog
2CXH_A       110 RPdnIVSFIVKGVSLSRERRWglpslrGG-----E--VLVARPL--------DSG-------------------VAV--- 152 Aeropyrum perni...
XP_001349334 125 ----SLTFSVQSYTTSTLIKSly---lKNvy--cN--FNKLKPLlilknfnnTSN-------------------TEMsny 174 Plasmodium falc...
XP_765007    109 GP--TFTFQINKVSLISDISKhy---tNp----qSfdSSNYSPLlvlngfskSSFkgsdedetkdessrfdkamTRV--- 176 Theileria parva...
XP_843876     96 GP--TLTFRVLSFTLRDEIVAkq---rRPanlgnA--VWNVAPIvvlnnfthPDArlr-------------pevPLL--- 152 Trypanosoma bru...
XP_001462818 100 GP--TLSFRVLSFTLHKEIVAkq---rRPvavdrA--AWEVAPIvvlnnfthPDLahr-------------aevPLL--- 156 Leishmania infa...
NP_001191384 103 GP--TLHFKVLKYSLSKDVVSsv---kKPktsqgQ---YRTAPLlvlnefktKDSkttdin--------svnpqKLC--- 163 Ciona intestinalis
NP_001191417 104 GP--TLSFKVNQYSLMKDVVSsl---kKHrmheeQ---FTHPPLlvlnnfgnQGMh-----------------vKLM--- 155 western clawed ...
NP_001191389 105 GP--TLTFRVTEYALIKDVISal---rRHrmheqQ---FTHHPLlvlnnmglEGMq-----------------vKLM--- 156 platypus
NP_001191381 105 GP--TLTFGVTKYSLVRDVVSsl---rRHrmheqQ---FSHPPLlvlngfgpHGLh-----------------vKLT--- 156 gray short-tail...
NP_001191368 105 GP--TLTFRINKYTLVRDVVSsl---rRHrmheqQ---FAHPPLlvlnsfgpHGMh-----------------vKLM--- 156 dog
2CXH_A       153 ----EFADAFVIAFHaRLkppeaaGYVEAVIESLDAR--TVAVTF----------------------------------- 191 Aeropyrum perni...
XP_001349334 175 liitQNILKNLYPSV-NLnedfmnKPRRVLLYCYNDNdqTIYFRQyatn------------------------------- 222 Plasmodium falc...
XP_765007    177 ----TETLNKMIAPV-DLsttkiqnCKRVVLFHKQKd-gTIVLRHysinlvdcntqaqvkdlltrktmknlisetsdfed 250 Theileria parva...
XP_843876    153 ----ETTFKGMFPTV-NIqlvkntDIQRVCLFHYDHVehVVEVRHyyinakavgvsktvkkllerrcptklgqlesid-- 225 Trypanosoma bru...
XP_001462818 157 ----MATFKALFPSL-NVqtiqssEIQRICLFHYDHVehVVEVRHyyvnartvgvtktvkkllenrrptklgtlesid-- 229 Leishmania infa...
NP_001191384 164 ----ATMLQNMFPSI-NIhkvnlnHVQRCVLFNNVEDn-rIEFRHyniavkpigmsrrmkkivtqrnipnlgkladisdy 237 Ciona intestinalis
NP_001191417 156 ----ATMFQNMFPSI-NVhkvnlnTIRRCILINYDDEtqQLDFRHyslkvvpvgmskgmkkllqekfpnmsrwedisell 230 western clawed ...
NP_001191389 157 ----ASMFQNMFPSI-NVhkvslnTIKRCLLISYNPEtqLLDFRHyslkvvpvgasrglkkllqekfpnmrrlqdisell 231 platypus
NP_001191381 157 ----ASVFQNMFPSI-NVhkvnlnCVKRCLLLSYDPDsqELQFRHyslkvvpvgasrgmkkllqekfpnmsrledvsell 231 gray short-tail...
NP_001191368 157 ----ATMFQNLFPSI-NVhkvnlnTIKRCLLINYNPDsqELDFRHysikvvpvgasrgmkkllqekfpnmsrlqdisell 231 dog
2CXH_A       192 ---------------------------------------------------------R---------------------- 192 Aeropyrum perni...
XP_001349334 223 -----------------------------------------------------lkkiSfkkilkeaynedmsgyndvfny 249 Plasmodium falc...
XP_765007    251 itnmlssdstlsknsnfdsdtdeiveldnilsqniiaknkygvdlepsetsdtrnkiG---------------------- 308 Theileria parva...
XP_843876    226 -------------------------evleredvwsdtdgegeevplavpfrkhreqcR---------------------- 258 Trypanosoma bru...
XP_001462818 230 -------------------------evldredawsdtdgegeevplvqpfrqhreqcR---------------------- 262 Leishmania infa...
NP_001191384 238 ltn-----------------hgdgsasesepelddqtnevelpqkmvgagnmkshqsA---------------------- 278 Ciona intestinalis
NP_001191417 231 v--------------------kganlseseaeqdgdhnitelpqacagrgnmkaqqsA---------------------- 268 western clawed ...
NP_001191389 232 v--------------------tganlsdseaeqdgdhnvmelpqvysgrgnmkaqqsA---------------------- 269 platypus
NP_001191381 232 a--------------------tgaglseseaepdgehnvtelpqayagrgnmkaeqsA---------------------- 269 gray short-tail...
NP_001191368 232 a--------------------tgaglseseaepdgehnitelpqavagrgnmraqqsA---------------------- 269 dog
2CXH_A       193 ---------------YGGAPVGPXLRL 204 Aeropyrum pernix K1
XP_001349334 250 lsskldgkhfntdtiSQMLEIGPRVSY 276 Plasmodium falciparum 3D7
XP_765007    309 ---------------IRLVEIGPRVQL 320 Theileria parva strain Muguga
XP_843876    259 ---------------IKLQEIGPRLTL 270 Trypanosoma brucei TREU927
XP_001462818 263 ---------------VKLQEIGPRMTL 274 Leishmania infantum JPCM5
NP_001191384 279 ---------------IRLTELGPRLML 290 Ciona intestinalis
NP_001191417 269 ---------------VRLTEIGPRMTL 280 western clawed frog
NP_001191389 270 ---------------VRLTEIGPRMTL 281 platypus
NP_001191381 270 ---------------VRLTEIGPRMTL 281 gray short-tailed opossum
NP_001191368 270 ---------------VRLTEIGPRMTL 281 dog
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